Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All FURIN 0 genome.wustl.edu 37 15 91424578 91424579 + Frame_Shift_Ins INS - - C TCGA-A8-A08C-01A-11W-A019-09 TCGA-A8-A08C-10A-01W-A021-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 54c486e6-9a10-4fcc-877d-f587f772cfd6 1e1356c6-9919-47fc-9d6b-ad2ac256249c 15 91424578 91424579 - C INS FURIN ENST00000268171 human ensembl 69_37n +1 known frame_shift_ins c.1855_1856 p.Q621fs 0.589:0.586 superfamily_Growth_fac_rcpt pfam_Peptidase_S8/S53,pfam_PrprotnconvertsP,superfamily_Peptidase_S8/S53,superfamily_Galactose-bd-like,superfamily_Prot_inh_propept,superfamily_Growth_fac_rcpt,smart_Furin_repeat,prints_Peptidase_S8_subtilisin-rel - no_errors FURIN HGNC ENSG00000140564 11 0 0.00 13 3 18.75 - - - GNAS 0 genome.wustl.edu 37 20 57429300 57429301 + Frame_Shift_Ins INS - - C TCGA-A8-A08C-01A-11W-A019-09 TCGA-A8-A08C-10A-01W-A021-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 54c486e6-9a10-4fcc-877d-f587f772cfd6 1e1356c6-9919-47fc-9d6b-ad2ac256249c 20 57429300 57429301 - C INS GNAS ENST00000371100 human ensembl 69_37n +1 putative frame_shift_ins c.980_981 p.I330fs 1.000:1.000 NULL pfam_Gprotein_alpha_su,pfam_Small_GTPase_ARF/SAR,superfamily_GproteinA_insert,smart_Gprotein_alpha_su,prints_Gprotein_alpha_S,prints_Gprotein_alpha_su - no_errors GNAS HGNC ENSG00000087460 10 0 0.00 4 2 33.33 - - - THEM5 0 genome.wustl.edu 37 1 151819737 151819738 + Frame_Shift_Del DEL GG GG - TCGA-A8-A08C-01A-11W-A019-09 TCGA-A8-A08C-10A-01W-A021-09 GG GG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 54c486e6-9a10-4fcc-877d-f587f772cfd6 1e1356c6-9919-47fc-9d6b-ad2ac256249c 1 151819737 151819738 GG - DEL THEM5 ENST00000453881 human ensembl 69_37n -1 known frame_shift_del c.642_641 p.P214fs 0.878:0.888 NULL pfam_Thioestr_supf - no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region THEM5 HGNC ENSG00000196407 11 0 0.00 4 2 33.33 - - -