Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All AGBL1 0 genome.wustl.edu 37 15 86768172 86768172 + Missense_Mutation SNP G G T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 15 86768172 86768172 G T SNP AGBL1 ENST00000441037 human ensembl 69_37n +1 known missense c.378 p.L126F 1.000 superfamily_ARM-type_fold pfam_Peptidase_M14,superfamily_ARM-type_fold - no_errors AGBL1 HGNC ENSG00000166748 103 0 0.00 100 36 26.47 - - - ANKRD17 0 genome.wustl.edu 37 4 73942663 73942663 + Missense_Mutation SNP A A C TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 4 73942663 73942663 A C SNP ANKRD17 ENST00000558247 human ensembl 69_37n -1 known missense c.7397 p.L2466R 1.000 NULL pfam_Ankyrin_rpt,pfam_KH_dom_type_1,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_KH_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_KH_dom_type_1,prints_Ankyrin_rpt - no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region ANKRD17 HGNC ENSG00000132466 55 0 0.00 40 11 21.57 - - - APOBR 0 genome.wustl.edu 37 16 28507424 28507424 + Silent SNP C C T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 16 28507424 28507424 C T SNP APOBR ENST00000564831 human ensembl 69_37n +1 known silent c.1062 p.A354 0.000 NULL NULL - no_errors APOBR HGNC ENSG00000184730 16 0 0.00 30 11 26.83 - - - ARFGEF2 0 genome.wustl.edu 37 20 47607613 47607613 + Missense_Mutation SNP T T C TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 20 47607613 47607613 T C SNP ARFGEF2 ENST00000371917 human ensembl 69_37n +1 known missense c.2851 p.F951L 1.000 superfamily_ARM-type_fold pfam_Sec7,pfam_DUF1981_SEC7_assoc,superfamily_Sec7,superfamily_ARM-type_fold,smart_Sec7,pfscan_Sec7 - no_errors ARFGEF2 HGNC ENSG00000124198 100 0 0.00 52 32 38.10 - - - AVL9 0 genome.wustl.edu 37 7 32598971 32598971 + Missense_Mutation SNP T T G TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 7 32598971 32598971 T G SNP AVL9 ENST00000404479 human ensembl 69_37n +1 known missense c.1110 p.I370M 1.000 pfam_Secretory_pathway_prot_Avl9 pfam_Secretory_pathway_prot_Avl9,pfam_DUF2347 - no_errors AVL9 HGNC ENSG00000105778 13 0 0.00 9 6 40.00 - - - CNTD1 0 genome.wustl.edu 37 17 40956304 40956305 + Frame_Shift_Del DEL AA AA - TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 AA AA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 17 40956304 40956305 AA - DEL CNTD1 ENST00000588408 human ensembl 69_37n +1 known frame_shift_del c.307_308 p.K103fs 0.061:0.074 superfamily_Cyclin-like pfam_Cyclin_N,superfamily_Cyclin-like - no_errors CNTD1 HGNC ENSG00000176563 64 0 0.00 28 21 41.18 - - - FMN2 0 genome.wustl.edu 37 1 240370352 240370352 + Missense_Mutation SNP C C T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 1 240370352 240370352 C T SNP FMN2 ENST00000319653 human ensembl 69_37n +1 known missense c.2240 p.S747F 0.999 NULL pfam_FH2_actin-bd,pfam_Formin_homology_1,superfamily_FH2_actin-bd,smart_Actin-bd_FH2/DRF_autoreg,pfscan_DEP_dom - no_errors FMN2 HGNC ENSG00000155816 36 0 0.00 20 17 45.95 - - - NEUROD6 0 genome.wustl.edu 37 7 31378167 31378167 + Missense_Mutation SNP G G A TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 7 31378167 31378167 G A SNP NEUROD6 ENST00000297142 human ensembl 69_37n -1 known missense c.716 p.A239V 0.992 pfam_Neurogenic_DUF,pirsf_TF_bHLH_NeuroD pfam_Neurogenic_DUF,pfam_HLH_DNA-bd,superfamily_HLH_DNA-bd,smart_HLH_DNA-bd,pirsf_TF_bHLH_NeuroD,pfscan_HLH_DNA-bd - no_errors NEUROD6 HGNC ENSG00000164600 31 0 0.00 26 23 46.94 - - - NME8 0 genome.wustl.edu 37 7 37896882 37896882 + Missense_Mutation SNP G G C TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 7 37896882 37896882 G C SNP NME8 ENST00000199447 human ensembl 69_37n +1 known missense c.205 p.A69P 1.000 pfam_Thioredoxin_domain,superfamily_Thioredoxin-like_fold pfam_Nucleoside_diP_kinase,pfam_Thioredoxin_domain,superfamily_Nucleoside_diP_kinase,superfamily_Thioredoxin-like_fold,smart_Nucleoside_diP_kinase - no_errors NME8 HGNC ENSG00000086288 119 0 0.00 103 21 16.80 - - - PGPEP1 0 genome.wustl.edu 37 19 18474258 18474258 + Silent SNP C C T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 19 18474258 18474258 C T SNP PGPEP1 ENST00000269919 human ensembl 69_37n +1 known silent c.495 p.A165 0.964 pfam_Peptidase_C15,superfamily_Peptidase_C15-like,pirsf_Peptidase_C15 pfam_Peptidase_C15,superfamily_Peptidase_C15-like,pirsf_Peptidase_C15,prints_Peptidase_C15 - no_errors PGPEP1 HGNC ENSG00000130517 57 0 0.00 36 20 35.71 - - - PHLDB3 0 genome.wustl.edu 37 19 44005930 44005930 + Missense_Mutation SNP G G T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 19 44005930 44005930 G T SNP PHLDB3 ENST00000292140 human ensembl 69_37n -1 known missense c.490 p.Q164K 0.972 NULL pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology - no_errors PHLDB3 HGNC ENSG00000176531 12 0 0.00 12 4 25.00 - - - PIK3CA 0 genome.wustl.edu 37 3 178952085 178952085 + Missense_Mutation SNP A A G TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 3 178952085 178952085 A G SNP PIK3CA ENST00000263967 human ensembl 69_37n +1 known missense c.3140 p.H1047R 1.000 superfamily_Kinase-like_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom - no_errors PIK3CA HGNC ENSG00000121879 55 0 0.00 26 26 50.00 - - - PLEKHB2 0 genome.wustl.edu 37 2 131883435 131883435 + Missense_Mutation SNP G G A TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 2 131883435 131883435 G A SNP PLEKHB2 ENST00000303908 human ensembl 69_37n +1 known missense c.147 p.M49I 1.000 pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology - no_errors PLEKHB2 HGNC ENSG00000115762 45 0 0.00 36 16 30.77 - - - SERPINB6 0 genome.wustl.edu 37 6 2955880 2955880 + Missense_Mutation SNP C C T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 6 2955880 2955880 C T SNP SERPINB6 ENST00000335686 human ensembl 69_37n -1 known missense c.190 p.G64S 0.452 pfam_Sepin_dom,superfamily_Sepin_dom,smart_Sepin_dom pfam_Sepin_dom,superfamily_Sepin_dom,smart_Sepin_dom - no_errors SERPINB6 HGNC ENSG00000124570 38 0 0.00 37 14 27.45 - - - SIT1 0 genome.wustl.edu 37 9 35649944 35649944 + Silent SNP G G A TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 9 35649944 35649944 G A SNP SIT1 ENST00000259608 human ensembl 69_37n -1 known silent c.492 p.P164 0.000 NULL NULL - no_errors SIT1 HGNC ENSG00000137078 30 0 0.00 12 9 42.86 - - - SOX3 0 genome.wustl.edu 37 X 139586876 139586876 + Missense_Mutation SNP G G T TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 X 139586876 139586876 G T SNP SOX3 ENST00000370536 human ensembl 69_37n -1 known missense c.350 p.A117E 0.021 NULL pfam_HMG_superfamily,pfam_TF_SOX,superfamily_HMG_superfamily,smart_HMG_superfamily,pfscan_HMG_superfamily - no_errors SOX3 HGNC ENSG00000134595 8 0 0.00 8 5 38.46 - - - SYNE1 0 genome.wustl.edu 37 6 152751745 152751745 + Nonsense_Mutation SNP G G A TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 6 152751745 152751745 G A SNP SYNE1 ENST00000265368 human ensembl 69_37n -1 known nonsense c.4561 p.R1521* 1.000 superfamily_Calpain_domain_III,superfamily_ABC_transptrTM_dom_typ1,smart_Spectrin/alpha-actinin pfam_Spectrin_repeat,pfam_CH-domain,pfam_KASH,superfamily_CH-domain,superfamily_Calpain_domain_III,superfamily_ABC_transptrTM_dom_typ1,smart_CH-domain,smart_Spectrin/alpha-actinin,pfscan_CH-domain,pfscan_KASH - no_errors SYNE1 HGNC ENSG00000131018 98 0 0.00 15 28 65.12 - - - TBCC 0 genome.wustl.edu 37 6 42712938 42712938 + Missense_Mutation SNP A A G TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 6 42712938 42712938 A G SNP TBCC ENST00000244625 human ensembl 69_37n -1 known missense c.874 p.Y292H 1.000 pfam_Tubulin-bd_cofactor_C pfam_Tubulin-bd_cofactor_C,smart_CARP_motif - no_errors TBCC HGNC ENSG00000124659 94 0 0.00 72 27 27.27 - - - TNKS1BP1 0 genome.wustl.edu 37 11 57077320 57077320 + Silent SNP G G A TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 11 57077320 57077320 G A SNP TNKS1BP1 ENST00000358252 human ensembl 69_37n -1 known silent c.2865 p.S955 0.000 NULL NULL - no_errors TNKS1BP1 HGNC ENSG00000149115 63 0 0.00 34 25 41.67 - - - ZNF281 0 genome.wustl.edu 37 1 200378731 200378732 + In_Frame_Ins INS - - GCC TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 1 200378731 200378732 - GCC INS ZNF281 ENST00000294740 human ensembl 69_37n -1 known in_frame_ins c.103_102 p.34in_frame_insG 0.985:0.997 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 - no_errors ZNF281 HGNC ENSG00000162702 10 0 0.00 4 2 33.33 - - - ZNF846 0 genome.wustl.edu 37 19 9868344 9868345 + Frame_Shift_Del DEL CG CG - TCGA-E2-A1IL-01A-11D-A14G-09 TCGA-E2-A1IL-10A-01D-A14G-09 CG CG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 1540ae03-7bb4-418b-afbc-44bf3ad60a31 6a5f0824-3724-42a3-af37-ca7215491e63 19 9868344 9868345 CG - DEL ZNF846 ENST00000397902 human ensembl 69_37n -1 known frame_shift_del c.1409_1408 p.R470fs 0.077:0.001 pfam_Znf_C2H2,smart_Znf_BED_prd,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,smart_Znf_BED_prd,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box - no_errors ZNF846 HGNC ENSG00000196605 72 0 0.00 45 13 22.03 - - -