Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	isArtifactMode	oxoGCut
CASZ1	54897	broad.mit.edu	37	1	10720212	10720212	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:10720212G>A	uc001aro.2	-	6	1207	c.887C>T	c.(886-888)TCG>TTG	p.S296L	CASZ1_uc001arp.1_Missense_Mutation_p.S296L|CASZ1_uc009vmx.2_Missense_Mutation_p.S320L|CASZ1_uc001arq.1_Missense_Mutation_p.S155L	NM_001079843	NP_001073312	Q86V15	CASZ1_HUMAN	castor homolog 1, zinc finger isoform a	296					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|zinc ion binding			skin(1)	1	Ovarian(185;0.203)|all_lung(157;0.204)	Lung NSC(185;4.96e-06)|all_lung(284;1.22e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00212)|Hepatocellular(190;0.00913)|Ovarian(437;0.0229)|Myeloproliferative disorder(586;0.0255)	STAD - Stomach adenocarcinoma(5;0.0224)	UCEC - Uterine corpus endometrioid carcinoma (279;0.0265)|Colorectal(212;3.54e-08)|COAD - Colon adenocarcinoma(227;9.56e-06)|BRCA - Breast invasive adenocarcinoma(304;0.000219)|Kidney(185;0.00142)|KIRC - Kidney renal clear cell carcinoma(229;0.00381)|READ - Rectum adenocarcinoma(331;0.0419)|STAD - Stomach adenocarcinoma(132;0.0623)		ACTGCTGTGCGACGGCAGGGG	0.657		NA											85	68					0	0	0	0
PRDM2	7799	broad.mit.edu	37	1	14075948	14075948	+	Silent	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:14075948C>A	uc001avi.2	+	6	1333	c.477C>A	c.(475-477)GCC>GCA	p.A159A	PRDM2_uc001avg.2_Silent_p.A159A|PRDM2_uc001avh.2_Silent_p.A159A|PRDM2_uc001avj.2_RNA|PRDM2_uc009vod.1_5'UTR|PRDM2_uc001avk.2_5'UTR|PRDM2_uc009voe.2_RNA|PRDM2_uc009vof.2_RNA	NM_012231	NP_036363	Q13029	PRDM2_HUMAN	retinoblastoma protein-binding zinc finger	159				A->V: Reduced histone methyltransferase activity.		Golgi apparatus|nucleus	DNA binding|histone-lysine N-methyltransferase activity|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(1)	1	Ovarian(185;0.249)	all_lung(284;2.56e-05)|Lung NSC(185;4.94e-05)|Renal(390;0.000147)|Breast(348;0.000162)|Colorectal(325;0.00058)|Ovarian(437;0.00965)|Hepatocellular(190;0.0245)|Myeloproliferative disorder(586;0.0255)	GBM - Glioblastoma multiforme(2;0.00182)	UCEC - Uterine corpus endometrioid carcinoma (279;0.00224)|Colorectal(212;3.23e-08)|BRCA - Breast invasive adenocarcinoma(304;2.16e-05)|COAD - Colon adenocarcinoma(227;2.53e-05)|Kidney(185;0.000762)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(313;0.00446)|READ - Rectum adenocarcinoma(331;0.0276)|Lung(427;0.145)		GAGCCAGCGCCCGGAGCAAGC	0.453		NA											8	13					2.18e-05	2.38e-05	1	0
RNF19B	127544	broad.mit.edu	37	1	33402524	33402524	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:33402524G>A	uc010oho.1	-	9	2082	c.2082C>T	c.(2080-2082)GCC>GCT	p.A694A	RNF19B_uc001bwm.3_3'UTR|RNF19B_uc010ohp.1_Silent_p.A693A	NM_153341	NP_699172	Q6ZMZ0	RN19B_HUMAN	ring finger protein 19B isoform a	694						integral to membrane	ligase activity|protein binding|zinc ion binding				0		Myeloproliferative disorder(586;0.0393)|all_neural(195;0.186)				TCGAGGGGCAGGCTGCAGTAT	0.587		NA											41	117					0	0	0	0
GBP3	2635	broad.mit.edu	37	1	89481070	89481070	+	Missense_Mutation	SNP	G	G	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:89481070G>C	uc001dmt.2	-	3	423	c.218C>G	c.(217-219)TCT>TGT	p.S73C	GBP3_uc010oss.1_Translation_Start_Site|GBP3_uc001dmu.2_Translation_Start_Site|GBP3_uc001dmv.2_RNA	NM_018284	NP_060754	Q9H0R5	GBP3_HUMAN	guanylate binding protein 3	73						integral to membrane	GTP binding|GTPase activity			ovary(1)|pancreas(1)	2		Lung NSC(277;0.123)		all cancers(265;0.0103)|Epithelial(280;0.0293)		TTTGGTGTGAGATTTCACTGT	0.483		NA											33	98					0	0	0	0
BTBD8	284697	broad.mit.edu	37	1	92604948	92604948	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:92604948A>G	uc001doo.2	+	6	1061	c.794A>G	c.(793-795)TAT>TGT	p.Y265C	BTBD8_uc010otc.1_RNA	NM_183242	NP_899065	Q5XKL5	BTBD8_HUMAN	BTB (POZ) domain containing 8	265	BTB 2.					nucleus				ovary(1)	1		all_lung(203;0.0484)|Lung NSC(277;0.126)|Glioma(108;0.222)		all cancers(265;0.0153)|Epithelial(280;0.0982)		CATTTTATATATGGAGGAACT	0.294		NA											22	97					0	0	0	0
FNDC7	163479	broad.mit.edu	37	1	109270438	109270438	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:109270438T>C	uc001dvx.2	+	7	1120	c.1120T>C	c.(1120-1122)TGT>CGT	p.C374R	FNDC7_uc010ova.1_Missense_Mutation_p.C141R	NM_001144937	NP_001138409	Q5VTL7	FNDC7_HUMAN	fibronectin type III domain containing 7	375						extracellular region				ovary(1)|skin(1)	2		all_lung(203;0.00439)|Lung NSC(277;0.00683)|all_epithelial(167;0.00728)		Colorectal(144;0.0314)|Lung(183;0.0924)|COAD - Colon adenocarcinoma(174;0.119)|Epithelial(280;0.173)|all cancers(265;0.244)		AGCTCCCTGTTGTCCTAGTGA	0.547		NA											44	131					0	0	0	0
PDE4DIP	9659	broad.mit.edu	37	1	144923767	144923767	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:144923767T>C	uc001elw.3	-	6	982	c.691A>G	c.(691-693)ATA>GTA	p.I231V	NBPF10_uc009wir.2_Intron|NBPF9_uc010oye.1_Intron|NBPF9_uc010oyf.1_Intron|NBPF9_uc010oyg.1_Intron|PDE4DIP_uc001elk.1_Intron|PDE4DIP_uc001ell.1_Intron|PDE4DIP_uc001elm.3_Intron|PDE4DIP_uc001eln.3_Intron|PDE4DIP_uc001elo.2_Intron|PDE4DIP_uc001elx.3_Missense_Mutation_p.I297V|PDE4DIP_uc001emc.1_Missense_Mutation_p.I231V|PDE4DIP_uc001emd.1_Missense_Mutation_p.I231V|PDE4DIP_uc001emb.1_Missense_Mutation_p.I394V|PDE4DIP_uc001eme.1_5'Flank|PDE4DIP_uc001emf.1_Missense_Mutation_p.I18V	NM_014644	NP_055459	Q5VU43	MYOME_HUMAN	phosphodiesterase 4D interacting protein isoform	231					cellular protein complex assembly	centrosome|Golgi apparatus|myofibril|nucleus	enzyme binding			ovary(4)|haematopoietic_and_lymphoid_tissue(1)	5				Colorectal(2;0.0829)|COAD - Colon adenocarcinoma(2;0.126)		TGCTGAGTTATAGTGGTCTCA	0.448		NA	T	PDGFRB	MPD								32	221					0	0	0	0
UBE2Q1	55585	broad.mit.edu	37	1	154524644	154524644	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:154524644G>A	uc001fff.1	-	8	982	c.891C>T	c.(889-891)AGC>AGT	p.S297S		NM_017582	NP_060052	Q7Z7E8	UB2Q1_HUMAN	ubiquitin-conjugating enzyme E2Q	297							ATP binding|protein binding|ubiquitin-protein ligase activity				0	all_lung(78;1.72e-29)|Lung NSC(65;2.96e-27)|Hepatocellular(266;0.0877)|all_hematologic(923;0.088)		LUSC - Lung squamous cell carcinoma(543;0.185)			TGTGCAAAGCGCTGTCCTGGT	0.493		NA											18	98					0	0	0	0
PLA2G4A	5321	broad.mit.edu	37	1	186946794	186946794	+	Missense_Mutation	SNP	T	T	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:186946794T>A	uc001gsc.2	+	16	2039	c.1834T>A	c.(1834-1836)TTT>ATT	p.F612I	PLA2G4A_uc010pos.1_Missense_Mutation_p.F552I	NM_024420	NP_077734	P47712	PA24A_HUMAN	cytosolic phospholipase A2, group IVA	612	PLA2c.				phospholipid catabolic process|platelet activating factor biosynthetic process|platelet activation	cytosol|endoplasmic reticulum membrane	calcium ion binding|calcium-dependent phospholipid binding|lysophospholipase activity			lung(2)|breast(1)	3					Flunisolide(DB00180)|Fluocinolone Acetonide(DB00591)|Fluocinonide(DB01047)|Fluorometholone(DB00324)|Flurandrenolide(DB00846)|Fluticasone Propionate(DB00588)|Medrysone(DB00253)|Quinacrine(DB01103)	TCCTTATGTGTTTGATCGGGA	0.418		NA											23	77					0	0	0	0
ASPM	259266	broad.mit.edu	37	1	197091601	197091601	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:197091601G>A	uc001gtu.2	-	14	3772	c.3515C>T	c.(3514-3516)ACG>ATG	p.T1172M	ASPM_uc001gtv.2_Missense_Mutation_p.T1172M|ASPM_uc001gtw.3_Intron	NM_018136	NP_060606	Q8IZT6	ASPM_HUMAN	asp (abnormal spindle)-like, microcephaly	1172	CH 2.				mitosis	cytoplasm|nucleus	calmodulin binding			ovary(4)|central_nervous_system(2)	6						ACCAGTTTGCGTACATTCCAC	0.413		NA											9	38					0	0	0	0
GREM2	64388	broad.mit.edu	37	1	240656691	240656691	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:240656691C>T	uc001hys.2	-	2	365	c.85G>A	c.(85-87)GCC>ACC	p.A29T		NM_022469	NP_071914	Q9H772	GREM2_HUMAN	gremlin 2 precursor	29					BMP signaling pathway	extracellular space	cytokine activity				0		all_cancers(173;0.0196)	OV - Ovarian serous cystadenocarcinoma(106;0.0123)			GAGGGGATGGCGCCCGCCGGC	0.622		NA											10	17					0	0	0	0
HNRNPU	3192	broad.mit.edu	37	1	245021401	245021401	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:245021401A>G	uc001iaz.1	-	7	1624	c.1406T>C	c.(1405-1407)ATA>ACA	p.I469T	HNRNPU_uc001iaw.1_RNA|HNRNPU_uc001iax.1_RNA|HNRNPU_uc001iay.1_Missense_Mutation_p.I193T|HNRNPU_uc001iba.1_Missense_Mutation_p.I450T|HNRNPU_uc001ibb.1_Missense_Mutation_p.I157T	NM_031844	NP_114032	Q00839	HNRPU_HUMAN	heterogeneous nuclear ribonucleoprotein U	469					CRD-mediated mRNA stabilization	catalytic step 2 spliceosome|cell surface|CRD-mediated mRNA stability complex|heterogeneous nuclear ribonucleoprotein complex|nucleoplasm	ATP binding|DNA binding|protein binding|RNA binding				0	all_cancers(71;6.97e-06)|all_epithelial(71;0.000104)|all_neural(11;0.0269)|Breast(184;0.0545)|Glioma(6;0.0724)|Ovarian(71;0.0761)|all_lung(81;0.0989)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.00868)			CTCTTCAGGTATTGGAAAATA	0.438		NA											13	49					0	0	0	0
PTEN	5728	broad.mit.edu	37	10	89692794	89692794	+	Missense_Mutation	SNP	A	A	G	rs121909238		TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr10:89692794A>G	uc001kfb.2	+	6	1309	c.278A>G	c.(277-279)CAT>CGT	p.H93R		NM_000314	NP_000305	P60484	PTEN_HUMAN	phosphatase and tensin homolog	93	Phosphatase tensin-type.		H -> R (in MCEPHAS).|H -> Y (in CD).	H->A: 75% reduction in phosphatase activity towards PtdIns(3,4,5)P3. Modest reduction in phosphatase activity towards PtdIns(3,4)P2.	activation of mitotic anaphase-promoting complex activity|apoptosis|canonical Wnt receptor signaling pathway|cell proliferation|central nervous system development|induction of apoptosis|inositol phosphate dephosphorylation|negative regulation of cell migration|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|negative regulation of focal adhesion assembly|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of protein kinase B signaling cascade|negative regulation of protein phosphorylation|nerve growth factor receptor signaling pathway|phosphatidylinositol dephosphorylation|phosphatidylinositol-mediated signaling|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of sequence-specific DNA binding transcription factor activity|protein stabilization|regulation of neuron projection development|T cell receptor signaling pathway	cytosol|internal side of plasma membrane|PML body	anaphase-promoting complex binding|enzyme binding|inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity|lipid binding|magnesium ion binding|PDZ domain binding|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity|phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity|phosphatidylinositol-3-phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity	p.R55fs*1(4)|p.H93Y(3)|p.H93Q(3)|p.?(2)|p.Y27fs*1(2)|p.Y27_N212>Y(2)|p.H93fs*5(1)|p.H93D(1)|p.H93R(1)|p.Q87_P96del(1)|p.N82_P95del(1)|p.F90_P95>L(1)|p.F56fs*2(1)		endometrium(831)|central_nervous_system(657)|skin(121)|haematopoietic_and_lymphoid_tissue(101)|large_intestine(99)|prostate(97)|breast(73)|lung(65)|ovary(58)|thyroid(29)|stomach(29)|upper_aerodigestive_tract(25)|cervix(24)|liver(20)|vulva(17)|kidney(15)|NS(14)|soft_tissue(13)|urinary_tract(12)|eye(8)|pancreas(6)|salivary_gland(5)|bone(5)|biliary_tract(4)|autonomic_ganglia(2)|meninges(2)|testis(1)|oesophagus(1)	2334		all_cancers(4;3.61e-31)|all_epithelial(4;3.96e-23)|Prostate(4;8.12e-23)|Breast(4;0.000111)|Melanoma(5;0.00146)|all_hematologic(4;0.00227)|Colorectal(252;0.00494)|all_neural(4;0.00513)|Acute lymphoblastic leukemia(4;0.0116)|Glioma(4;0.0274)|all_lung(38;0.132)	KIRC - Kidney renal clear cell carcinoma(1;0.214)	UCEC - Uterine corpus endometrioid carcinoma (6;0.000228)|all cancers(1;4.16e-84)|GBM - Glioblastoma multiforme(1;7.77e-49)|Epithelial(1;7.67e-41)|OV - Ovarian serous cystadenocarcinoma(1;6.22e-15)|BRCA - Breast invasive adenocarcinoma(1;1.1e-06)|Lung(2;3.18e-06)|Colorectal(12;4.88e-06)|LUSC - Lung squamous cell carcinoma(2;4.97e-06)|COAD - Colon adenocarcinoma(12;1.13e-05)|Kidney(1;0.000288)|KIRC - Kidney renal clear cell carcinoma(1;0.00037)|STAD - Stomach adenocarcinoma(243;0.218)		TTTGAAGACCATAACCCACCA	0.338		31	D|Mis|N|F|S		glioma| prostate|endometrial	harmartoma|glioma| prostate|endometrial			Proteus_syndrome|Cowden_syndrome|Juvenile_Polyposis|Hereditary_Mixed_Polyposis_Syndrome_type_1|Bannayan-Riley-Ruvalcaba_syndrome	HNSCC(9;0.0022)|TCGA GBM(2;<1E-08)|TSP Lung(26;0.18)			21	63					0	0	0	0
TLL2	7093	broad.mit.edu	37	10	98155039	98155039	+	Missense_Mutation	SNP	G	G	A	rs140011074		TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr10:98155039G>A	uc001kml.1	-	13	1857	c.1631C>T	c.(1630-1632)CCG>CTG	p.P544L	TLL2_uc009xvf.1_Missense_Mutation_p.P522L	NM_012465	NP_036597	Q9Y6L7	TLL2_HUMAN	tolloid-like 2 precursor	544	CUB 2.				cell differentiation|multicellular organismal development|proteolysis	extracellular region	calcium ion binding|metalloendopeptidase activity|zinc ion binding			ovary(1)|pancreas(1)|skin(1)	3		Colorectal(252;0.0846)		Epithelial(162;1.51e-07)|all cancers(201;7.59e-06)		CACATCCTCCGGCTTCTCATA	0.507		NA											4	87					0	0	0	0
TH	7054	broad.mit.edu	37	11	2190937	2190937	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:2190937G>A	uc001lvq.2	-	3	367	c.348C>T	c.(346-348)CTC>CTT	p.L116L	TH_uc001lvp.2_Silent_p.L112L|TH_uc001lvr.2_Silent_p.L85L|TH_uc010qxj.1_Silent_p.L89L|TH_uc001lvs.2_Silent_p.L85L|TH_uc001lvt.2_Silent_p.L89L|TH_uc009ydh.1_5'Flank	NM_199292	NP_954986	P07101	TY3H_HUMAN	tyrosine hydroxylase isoform a	116					dopamine biosynthetic process from tyrosine|embryonic camera-type eye morphogenesis|epinephrine biosynthetic process|eye photoreceptor cell development|heart morphogenesis|hormone biosynthetic process|learning|locomotory behavior|memory|neurotransmitter biosynthetic process|neurotransmitter secretion|norepinephrine biosynthetic process|pigmentation|regulation of heart contraction|response to ethanol|response to hypoxia|synaptic transmission, dopaminergic|visual perception	cytosol|internal side of plasma membrane|melanosome membrane|nucleus|perikaryon|smooth endoplasmic reticulum	protein binding|tyrosine 3-monooxygenase activity				0		all_epithelial(84;1.46e-23)|Lung NSC(207;4.44e-11)|all_lung(207;1.11e-09)|Ovarian(85;1.78e-06)|Breast(177;1.78e-05)|Medulloblastoma(188;0.0208)|all_neural(188;0.0416)	Colorectal(5;0.00245)|COAD - Colon adenocarcinoma(6;0.0239)	BRCA - Breast invasive adenocarcinoma(625;8.45e-09)|Lung(200;0.000152)|LUSC - Lung squamous cell carcinoma(625;0.00154)	L-Phenylalanine(DB00120)|L-Tyrosine(DB00135)|Metyrosine(DB00765)|Tetrahydrobiopterin(DB00360)	TCGGGGAGAAGAGCAGGTTTA	0.672		NA											30	71					0	0	0	0
OR52B2	255725	broad.mit.edu	37	11	6191145	6191145	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:6191145G>A	uc010qzy.1	-	1	412	c.412C>T	c.(412-414)CTA>TTA	p.L138L		NM_001004052	NP_001004052	Q96RD2	O52B2_HUMAN	olfactory receptor, family 52, subfamily B,	138	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0		Medulloblastoma(188;0.00776)|all_neural(188;0.0652)|Breast(177;0.114)		Epithelial(150;3.69e-08)|BRCA - Breast invasive adenocarcinoma(625;0.135)		GGCCATGTTAGCACTGTTGTA	0.512		NA											9	49					0	0	0	0
ABCC8	6833	broad.mit.edu	37	11	17428479	17428479	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:17428479C>T	uc001mnc.2	-	25	3244	c.3118G>A	c.(3118-3120)GCC>ACC	p.A1040T		NM_000352	NP_000343	Q09428	ABCC8_HUMAN	ATP-binding cassette, sub-family C, member 8	1040	ABC transmembrane type-1 2.|Extracellular (By similarity).				carbohydrate metabolic process|energy reserve metabolic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances|potassium ion transmembrane transporter activity|sulfonylurea receptor activity			ovary(1)	1				READ - Rectum adenocarcinoma(2;0.0325)|Colorectal(2;0.1)	Adenosine triphosphate(DB00171)|Glibenclamide(DB01016)|Gliclazide(DB01120)|Mitiglinide(DB01252)|Nateglinide(DB00731)|Repaglinide(DB00912)	AGGGTCAGGGCGCTGTCGGTC	0.652		NA											6	87					0	0	0	0
SLC5A12	159963	broad.mit.edu	37	11	26734241	26734241	+	Nonsense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:26734241G>A	uc001mra.2	-	2	665	c.352C>T	c.(352-354)CGA>TGA	p.R118*	SLC5A12_uc001mrb.2_RNA|SLC5A12_uc001mrc.3_Nonsense_Mutation_p.R118*	NM_178498	NP_848593	Q1EHB4	SC5AC_HUMAN	solute carrier family 5 (sodium/glucose	118	Cytoplasmic (Potential).				sodium ion transport	apical plasma membrane|integral to membrane	symporter activity			ovary(1)|skin(1)	2						TTGTTGAATCGTAGTTGTAAG	0.418		NA											60	189					0	0	0	0
TTC17	55761	broad.mit.edu	37	11	43418289	43418289	+	Missense_Mutation	SNP	G	G	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:43418289G>T	uc001mxi.2	+	6	708	c.694G>T	c.(694-696)GCT>TCT	p.A232S	TTC17_uc001mxh.2_Missense_Mutation_p.A232S|TTC17_uc010rfj.1_Missense_Mutation_p.A175S|TTC17_uc001mxj.2_Missense_Mutation_p.A2S	NM_018259	NP_060729	Q96AE7	TTC17_HUMAN	tetratricopeptide repeat domain 17	232							binding			ovary(5)	5						GTATAACATGGCTTCATTTTA	0.388		NA											15	66					0.000308642	0.000330281	1	0
FAT3	120114	broad.mit.edu	37	11	92613978	92613978	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:92613978G>A	uc001pdj.3	+	22	12226	c.12209G>A	c.(12208-12210)CGG>CAG	p.R4070Q	FAT3_uc001pdi.3_Missense_Mutation_p.R510Q	NM_001008781	NP_001008781	Q8TDW7	FAT3_HUMAN	FAT tumor suppressor homolog 3	4070	EGF-like 3.|Extracellular (Potential).				homophilic cell adhesion|multicellular organismal development	integral to membrane|plasma membrane	calcium ion binding			ovary(4)|pancreas(1)	5		Acute lymphoblastic leukemia(157;3.01e-05)|all_hematologic(158;0.00858)				AACCCCTGCCGGAATGGAGGA	0.478		NA								TCGA Ovarian(4;0.039)			6	179					0	0	0	0
OR8D2	283160	broad.mit.edu	37	11	124189328	124189328	+	Missense_Mutation	SNP	T	T	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr11:124189328T>A	uc010sah.1	-	1	766	c.766A>T	c.(766-768)ACA>TCA	p.T256S		NM_001002918	NP_001002918	Q9GZM6	OR8D2_HUMAN	olfactory receptor, family 8, subfamily D,	256	Helical; Name=6; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|central_nervous_system(1)|pancreas(1)	3		Breast(109;0.0115)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.22)		BRCA - Breast invasive adenocarcinoma(274;1.49e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0525)		TACATGAATGTTATAGACCCA	0.438		NA											37	81					0	0	0	0
AVPR1A	552	broad.mit.edu	37	12	63544069	63544069	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr12:63544069G>A	uc001sro.1	-	1	2522	c.548C>T	c.(547-549)ACG>ATG	p.T183M		NM_000706	NP_000697	P37288	V1AR_HUMAN	arginine vasopressin receptor 1A	183	Helical; Name=4; (Potential).				activation of phospholipase C activity|elevation of cytosolic calcium ion concentration|generation of precursor metabolites and energy	endosome|integral to plasma membrane	protein kinase C binding|vasopressin receptor activity				0			BRCA - Breast invasive adenocarcinoma(9;0.193)	GBM - Glioblastoma multiforme(28;0.0569)	Conivaptan(DB00872)|Desmopressin(DB00035)|Felypressin(DB00093)|Terlipressin(DB02638)|Vasopressin(DB00067)	GTACTGCGGCGTGCTCAGCAC	0.642		NA											29	50					0	0	0	0
KDM2B	84678	broad.mit.edu	37	12	122018774	122018774	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr12:122018774G>A	uc001uat.2	-	1	147	c.43C>T	c.(43-45)CCA>TCA	p.P15S	KDM2B_uc001uas.2_5'Flank|KDM2B_uc001uau.2_5'UTR|KDM2B_uc001uav.3_Missense_Mutation_p.P15S	NM_032590	NP_115979	Q8NHM5	KDM2B_HUMAN	F-box and leucine-rich repeat protein 10 isoform	15					embryonic camera-type eye morphogenesis|fourth ventricle development|histone H2A monoubiquitination|initiation of neural tube closure|lateral ventricle development|midbrain development|midbrain-hindbrain boundary morphogenesis|negative regulation of neural precursor cell proliferation|negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter|spermatogenesis|third ventricle development|transcription, DNA-dependent	nucleolus	DNA binding|histone demethylase activity (H3-K36 specific)|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|protein binding|rRNA binding|zinc ion binding			ovary(1)|skin(1)	2						CTTTTTCGTGGGGGGTGATCC	0.483		NA											32	135					0	0	0	0
TPP2	7174	broad.mit.edu	37	13	103295686	103295686	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr13:103295686T>C	uc001vpi.3	+	17	2238	c.2135T>C	c.(2134-2136)CTT>CCT	p.L712P		NM_003291	NP_003282	P29144	TPP2_HUMAN	tripeptidyl peptidase II	712					proteolysis	cytoplasm|nucleus	aminopeptidase activity|serine-type endopeptidase activity|tripeptidyl-peptidase activity			upper_aerodigestive_tract(1)|ovary(1)	2	all_neural(89;0.0438)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)					TTTTGTTCTCTTCCAGAGAAA	0.373		NA											12	32					0	0	0	0
LRFN5	145581	broad.mit.edu	37	14	42360816	42360816	+	Silent	SNP	A	A	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr14:42360816A>T	uc001wvm.2	+	4	2947	c.1749A>T	c.(1747-1749)GTA>GTT	p.V583V	LRFN5_uc010ana.2_Intron	NM_152447	NP_689660	Q96NI6	LRFN5_HUMAN	leucine rich repeat and fibronectin type III	583	Cytoplasmic (Potential).					integral to membrane				ovary(5)|pancreas(2)|central_nervous_system(1)	8			LUAD - Lung adenocarcinoma(50;0.0223)|Lung(238;0.0728)	GBM - Glioblastoma multiforme(112;0.00847)		GCTGTAGTGTAACGCTGCCCC	0.453		NA								HNSCC(30;0.082)			22	48					0	0	0	0
PCNX	22990	broad.mit.edu	37	14	71500712	71500712	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr14:71500712G>A	uc001xmo.2	+	18	4179	c.3733G>A	c.(3733-3735)GAA>AAA	p.E1245K	PCNX_uc010are.1_Missense_Mutation_p.E1134K|PCNX_uc010arf.1_Missense_Mutation_p.E105K	NM_014982	NP_055797	Q96RV3	PCX1_HUMAN	pecanex-like 1	1245						integral to membrane				ovary(1)	1			KIRC - Kidney renal clear cell carcinoma(12;0.206)	all cancers(60;0.00835)|BRCA - Breast invasive adenocarcinoma(234;0.00951)|OV - Ovarian serous cystadenocarcinoma(108;0.0417)		CCCTCTATCTGAAGTAAAAGA	0.308		NA											35	87					0	0	0	0
C15orf42	90381	broad.mit.edu	37	15	90168261	90168261	+	Nonsense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr15:90168261C>T	uc002boe.2	+	20	4720	c.4720C>T	c.(4720-4722)CGA>TGA	p.R1574*	C15orf42_uc010upv.1_RNA	NM_152259	NP_689472	Q7Z2Z1	TICRR_HUMAN	leucine-rich repeat kinase 1	1574					cell cycle|DNA repair|DNA replication|formation of translation preinitiation complex|G2/M transition checkpoint|mitotic cell cycle DNA replication checkpoint|regulation of DNA-dependent DNA replication initiation|response to ionizing radiation	nucleus	chromatin binding|protein binding			ovary(4)|central_nervous_system(2)|skin(1)	7	Lung NSC(78;0.0237)|all_lung(78;0.0478)		BRCA - Breast invasive adenocarcinoma(143;0.128)			TCCCAAACTTCGAATTAAGAA	0.537		NA											32	98					0	0	0	0
RBBP6	5930	broad.mit.edu	37	16	24551988	24551988	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr16:24551988A>G	uc002dmh.2	+	1	1081	c.41A>G	c.(40-42)TAT>TGT	p.Y14C	RBBP6_uc010vcb.1_Intron|RBBP6_uc002dmg.2_Missense_Mutation_p.Y14C|RBBP6_uc002dmi.2_Missense_Mutation_p.Y14C|RBBP6_uc010bxr.2_Missense_Mutation_p.Y14C	NM_006910	NP_008841	Q7Z6E9	RBBP6_HUMAN	retinoblastoma-binding protein 6 isoform 1	14	DWNN.				protein ubiquitination involved in ubiquitin-dependent protein catabolic process	chromosome|nucleolus|ubiquitin ligase complex	nucleic acid binding|protein binding|ubiquitin-protein ligase activity|zinc ion binding			ovary(3)|pancreas(1)	4				GBM - Glioblastoma multiforme(48;0.0518)		AAACTCAACTATGATACCGTC	0.473		NA											20	72					0	0	0	0
CCDC40	55036	broad.mit.edu	37	17	78063685	78063685	+	Splice_Site	SNP	T	T	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr17:78063685T>G	uc010dht.2	+	17	2859	c.2832_splice	c.e17+2	p.K944_splice	CCDC40_uc002jxm.3_Splice_Site_p.K727_splice|CCDC40_uc002jxn.3_Splice_Site_p.K340_splice	NM_017950	NP_060420	Q4G0X9	CCD40_HUMAN	coiled-coil domain containing 40						axonemal dynein complex assembly|ciliary cell motility|cilium movement involved in determination of left/right asymmetry|flagellar cell motility	cilium|cytoplasm				ovary(3)	3	all_neural(118;0.167)		OV - Ovarian serous cystadenocarcinoma(97;0.0292)|BRCA - Breast invasive adenocarcinoma(99;0.149)			AGGATGAAGGTGAGGGGAGGA	0.627		NA											10	32					0	0	0	0
PIP5K1C	23396	broad.mit.edu	37	19	3648623	3648623	+	Missense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr19:3648623C>A	uc002lyj.1	-	9	1268	c.1211G>T	c.(1210-1212)AGG>ATG	p.R404M	PIP5K1C_uc010xhq.1_Missense_Mutation_p.R404M|PIP5K1C_uc010xhr.1_Missense_Mutation_p.R404M	NM_012398	NP_036530	O60331	PI51C_HUMAN	phosphatidylinositol-4-phosphate 5-kinase, type	404	PIPK.				axon guidance	cytosol|plasma membrane	1-phosphatidylinositol-4-phosphate 5-kinase activity|ATP binding			stomach(2)|skin(2)	4		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.95e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0026)|STAD - Stomach adenocarcinoma(1328;0.183)		GGGCACCCACCTGTAGGACTG	0.706		NA											15	57					5.39e-06	5.97e-06	1	0
CCDC94	55702	broad.mit.edu	37	19	4267629	4267629	+	Silent	SNP	G	G	A	rs144896215	byFrequency	TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr19:4267629G>A	uc002lzv.3	+	7	750	c.717G>A	c.(715-717)AAG>AAA	p.K239K		NM_018074	NP_060544	Q9BW85	CCD94_HUMAN	coiled-coil domain containing 94	239											0				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0348)|STAD - Stomach adenocarcinoma(1328;0.183)		AGGCCCCAAAGCCCAAGAGGA	0.687		NA									OREG0025164	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	14	37					0	0	0	0
ZNRF4	148066	broad.mit.edu	37	19	5455922	5455922	+	Silent	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr19:5455922C>T	uc002mca.3	+	1	497	c.420C>T	c.(418-420)AAC>AAT	p.N140N		NM_181710	NP_859061	Q8WWF5	ZNRF4_HUMAN	zinc and ring finger 4 precursor	140	Extracellular (Potential).|PA.					integral to membrane	zinc ion binding			large_intestine(2)	2				UCEC - Uterine corpus endometrioid carcinoma (162;0.0002)		AGCCAGCCAACGCGTGCCATC	0.672		NA											22	67					0	0	0	0
MUC16	94025	broad.mit.edu	37	19	8966769	8966769	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr19:8966769A>G	uc002mkp.2	-	81	43388	c.43184T>C	c.(43183-43185)TTC>TCC	p.F14395S	MUC16_uc010dwi.2_RNA|MUC16_uc010dwj.2_Missense_Mutation_p.F1195S|MUC16_uc010xki.1_RNA	NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	mucin 16	Error:AA_residue_mismatch_between_GAF_and_UniProt_prot_seqs_after_alignment					cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			lung(30)|ovary(15)|breast(8)|large_intestine(1)|skin(1)|prostate(1)|pancreas(1)	57						CAGTGGCGAGAAGTTACACAG	0.527		NA											2	7					0	0	0	0
PRR12	57479	broad.mit.edu	37	19	50099696	50099696	+	Missense_Mutation	SNP	A	A	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr19:50099696A>T	uc002poo.3	+	4	2104	c.2104A>T	c.(2104-2106)AGT>TGT	p.S702C		NM_020719	NP_065770	Q9ULL5	PRR12_HUMAN	proline rich 12	Error:AA_residue_mismatch_between_GAF_and_UniProt_prot_seqs_after_alignment							DNA binding			central_nervous_system(1)|pancreas(1)	2		all_lung(116;2.45e-07)|Lung NSC(112;1.24e-06)|Ovarian(192;0.0728)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00319)|GBM - Glioblastoma multiforme(134;0.0132)		CCACCTGCAGAGTGTCATCCG	0.657		NA											14	20					0	0	0	0
ZNF543	125919	broad.mit.edu	37	19	57839395	57839395	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr19:57839395G>A	uc002qoi.1	+	4	910	c.565G>A	c.(565-567)GAT>AAT	p.D189N		NM_213598	NP_998763	Q08ER8	ZN543_HUMAN	zinc finger protein 543	189					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(1)|pancreas(1)	2		Colorectal(82;0.000256)|all_neural(62;0.0577)|Ovarian(87;0.221)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0257)		ACCAGTTACAGATGCCTTGAT	0.403		NA											29	81					0	0	0	0
BRE	9577	broad.mit.edu	37	2	28210901	28210901	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:28210901G>A	uc002rlr.2	+	5	565	c.247G>A	c.(247-249)GAT>AAT	p.D83N	BRE_uc002rlp.1_Missense_Mutation_p.D83N|BRE_uc002rlq.2_Missense_Mutation_p.D83N|BRE_uc002rls.2_Missense_Mutation_p.D83N|BRE_uc002rlt.2_Missense_Mutation_p.D83N|BRE_uc002rlu.2_Missense_Mutation_p.D83N|BRE_uc002rlv.2_5'UTR	NM_199194	NP_954664	Q9NXR7	BRE_HUMAN	brain and reproductive organ-expressed (TNFRSF1A	83	UEV-like 1.				apoptosis|chromatin modification|double-strand break repair|G2/M transition DNA damage checkpoint|positive regulation of anti-apoptosis|positive regulation of DNA repair|response to ionizing radiation|signal transduction	BRCA1-A complex|BRISC complex|cytoplasm|nuclear ubiquitin ligase complex	peroxisome targeting sequence binding|polyubiquitin binding|tumor necrosis factor receptor binding			lung(1)|kidney(1)|skin(1)	3	Acute lymphoblastic leukemia(172;0.155)					ACTGCCTCCCGATTTTATCTT	0.398		NA											94	326					0	0	0	0
RAB1A	5861	broad.mit.edu	37	2	65318142	65318142	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:65318142A>G	uc002sdm.2	-	4	649	c.263T>C	c.(262-264)ATA>ACA	p.I88T	RAB1A_uc002sdn.2_Intron|RAB1A_uc010yqe.1_Intron|RAB1A_uc002sdo.2_Intron	NM_004161	NP_004152	P62820	RAB1A_HUMAN	RAB1A, member RAS oncogene family isoform 1	88					protein transport|small GTPase mediated signal transduction|vesicle-mediated transport	endoplasmic reticulum|Golgi apparatus	GTP binding|GTPase activity				0						ATACACAACTATGATGCCATG	0.398		NA											4	26					0	0	0	0
ZNF638	27332	broad.mit.edu	37	2	71633384	71633384	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:71633384A>G	uc002shx.2	+	19	3446	c.3127A>G	c.(3127-3129)AGA>GGA	p.R1043G	ZNF638_uc010yqw.1_Missense_Mutation_p.R622G|ZNF638_uc002shy.2_Missense_Mutation_p.R1043G|ZNF638_uc002shz.2_Missense_Mutation_p.R1043G|ZNF638_uc002sia.2_Missense_Mutation_p.R1043G|ZNF638_uc002sib.1_Missense_Mutation_p.R1043G|ZNF638_uc010fed.2_RNA|ZNF638_uc002sic.2_Missense_Mutation_p.R140G	NM_014497	NP_055312	Q14966	ZN638_HUMAN	zinc finger protein 638	1043					RNA splicing	cytoplasm|nuclear speck	double-stranded DNA binding|nucleotide binding|RNA binding|zinc ion binding			pancreas(2)|ovary(1)|skin(1)	4						CATAAGTAATAGAAACAAGGT	0.343		NA											14	40					0	0	0	0
REG3A	5068	broad.mit.edu	37	2	79385538	79385538	+	Missense_Mutation	SNP	C	C	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:79385538C>G	uc002sod.1	-	3	502	c.247G>C	c.(247-249)GCT>CCT	p.A83P	REG3A_uc002soe.1_Missense_Mutation_p.A83P|REG3A_uc002sof.1_Missense_Mutation_p.A83P	NM_138938	NP_620355	Q06141	REG3A_HUMAN	pancreatitis-associated protein precursor	83	C-type lectin.				acute-phase response|cell proliferation|heterophilic cell-cell adhesion|multicellular organismal development	cytoplasm|extracellular space|soluble fraction	sugar binding			skin(1)	1						GATCCCTCAGCCCCACTGAGC	0.572		NA											12	67					0	0	0	0
FAHD2A	51011	broad.mit.edu	37	2	96072879	96072879	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:96072879G>A	uc002sur.2	+	3	615	c.436G>A	c.(436-438)GAG>AAG	p.E146K	FAHD2A_uc002sus.2_Missense_Mutation_p.E146K	NM_016044	NP_057128	Q96GK7	FAH2A_HUMAN	fumarylacetoacetate hydrolase domain containing	146							hydrolase activity|metal ion binding			ovary(1)	1						GCCCTATGATGAGGTGGTCCT	0.562		NA											18	88					0	0	0	0
CSRNP3	80034	broad.mit.edu	37	2	166533063	166533063	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:166533063G>A	uc002udf.2	+	6	1026	c.650G>A	c.(649-651)CGA>CAA	p.R217Q	CSRNP3_uc002udg.2_Missense_Mutation_p.R217Q	NM_024969	NP_079245	Q8WYN3	CSRN3_HUMAN	cysteine-serine-rich nuclear protein 3	217	Cys-rich.				apoptosis|positive regulation of apoptosis|positive regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity			ovary(3)|large_intestine(1)|skin(1)	5						TGTGACTGCCGAGTGTTCTGT	0.542		NA											21	50					0	0	0	0
COL4A4	1286	broad.mit.edu	37	2	227912248	227912248	+	Missense_Mutation	SNP	C	C	T	rs77277077	by1000genomes	TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr2:227912248C>T	uc010zlt.1	-	35	3886	c.3232G>A	c.(3232-3234)GCC>ACC	p.A1078T		NM_000092	NP_000083	P53420	CO4A4_HUMAN	alpha 4 type IV collagen precursor	1078	Triple-helical region.				axon guidance|glomerular basement membrane development	basal lamina|collagen type IV	extracellular matrix structural constituent|protein binding			ovary(5)|central_nervous_system(3)|pancreas(1)|breast(1)|skin(1)	11		Renal(207;0.00844)|all_lung(227;0.0187)|Lung NSC(271;0.0879)|all_hematologic(139;0.21)|Esophageal squamous(248;0.242)		Epithelial(121;6.7e-11)|all cancers(144;5.39e-08)|Lung(261;0.0132)|LUSC - Lung squamous cell carcinoma(224;0.0181)		AAGTGACTGGCAGGGTCACCT	0.398		NA											12	21					0	0	0	0
ANGPT4	51378	broad.mit.edu	37	20	896725	896725	+	Missense_Mutation	SNP	A	A	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr20:896725A>C	uc002wei.2	-	1	236	c.133T>G	c.(133-135)TAC>GAC	p.Y45D	ANGPT4_uc010zpn.1_Missense_Mutation_p.Y39D	NM_015985	NP_057069	Q9Y264	ANGP4_HUMAN	angiopoietin 4 precursor	45					anti-apoptosis|blood coagulation|cellular response to hypoxia|leukocyte migration|negative regulation of angiogenesis|negative regulation of blood vessel endothelial cell migration|positive regulation of angiogenesis|positive regulation of blood vessel endothelial cell migration|positive regulation of peptidyl-tyrosine phosphorylation|signal transduction	extracellular space	receptor tyrosine kinase binding|transmembrane receptor protein tyrosine kinase activator activity			ovary(2)	2						AAGAAGGTGTAGCTACAGTGG	0.607		NA											19	65					0	0	0	0
C20orf186	149954	broad.mit.edu	37	20	31671216	31671216	+	Silent	SNP	C	C	A	rs145261889	byFrequency	TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr20:31671216C>A	uc010zue.1	+	3	228	c.213C>A	c.(211-213)CCC>CCA	p.P71P		NM_182519	NP_872325	P59827	LPLC4_HUMAN	antimicrobial peptide RY2G5 precursor	71						cytoplasm|extracellular region	lipid binding				0						TCCGAGGACCCCCCCCAGTAT	0.488		NA											39	113					7.05e-23	8.63e-23	1	0
KIAA1755	85449	broad.mit.edu	37	20	36841569	36841569	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr20:36841569G>A	uc002xhy.1	-	14	3750	c.3478C>T	c.(3478-3480)CGG>TGG	p.R1160W	KIAA1755_uc002xhv.1_Missense_Mutation_p.R224W|KIAA1755_uc002xhw.1_Missense_Mutation_p.R215W|KIAA1755_uc002xhx.1_Missense_Mutation_p.R438W	NM_001029864	NP_001025035	Q5JYT7	K1755_HUMAN	hypothetical protein LOC85449	1160										ovary(4)|pancreas(1)	5		Myeloproliferative disorder(115;0.00874)				GGCTGCTGCCGGAAGAAGGTG	0.647		NA											17	74					0	0	0	0
PPP1R16B	26051	broad.mit.edu	37	20	37464808	37464808	+	Missense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr20:37464808C>A	uc002xje.2	+	2	429	c.240C>A	c.(238-240)GAC>GAA	p.D80E	PPP1R16B_uc010ggc.2_Missense_Mutation_p.D80E	NM_015568	NP_056383	Q96T49	PP16B_HUMAN	protein phosphatase 1 regulatory inhibitor	80					regulation of filopodium assembly|signal transduction	nucleus|plasma membrane	protein phosphatase binding			upper_aerodigestive_tract(1)|kidney(1)|skin(1)	3		Myeloproliferative disorder(115;0.00878)				TGAGGAACGACGCCGAGGAAG	0.652		NA											12	41					6.72e-11	7.83e-11	1	0
YWHAB	7529	broad.mit.edu	37	20	43530339	43530339	+	Silent	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr20:43530339C>T	uc002xmt.2	+	3	447	c.165C>T	c.(163-165)GGC>GGT	p.G55G	YWHAB_uc002xmu.2_Silent_p.G55G	NM_003404	NP_003395	P31946	1433B_HUMAN	tyrosine 3-monooxygenase/tryptophan	55					activation of MAPKK activity|activation of pro-apoptotic gene products|axon guidance|cytoplasmic sequestering of protein|epidermal growth factor receptor signaling pathway|induction of apoptosis by intracellular signals|insulin receptor signaling pathway|mRNA metabolic process|negative regulation of protein dephosphorylation|nerve growth factor receptor signaling pathway|Ras protein signal transduction	centrosome|cytosol|melanosome|perinuclear region of cytoplasm	histone deacetylase binding|phosphoserine binding|protein domain specific binding			kidney(2)|ovary(1)|breast(1)	4		Myeloproliferative disorder(115;0.0122)				ATGTGGTAGGCGCCCGCCGCT	0.512		NA											23	41					0	0	0	0
DIP2A	23181	broad.mit.edu	37	21	47977603	47977603	+	Missense_Mutation	SNP	C	C	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr21:47977603C>G	uc002zjo.2	+	31	3918	c.3735C>G	c.(3733-3735)TTC>TTG	p.F1245L	DIP2A_uc011afz.1_Missense_Mutation_p.F1241L|DIP2A_uc002zjr.2_Missense_Mutation_p.F212L	NM_015151	NP_055966	Q14689	DIP2A_HUMAN	disco-interacting protein 2A isoform a	1245					multicellular organismal development	nucleus	catalytic activity|transcription factor binding			ovary(2)	2	Breast(49;0.0933)			Epithelial(3;3.12e-06)|OV - Ovarian serous cystadenocarcinoma(3;5.68e-06)|all cancers(3;4.08e-05)|Colorectal(79;0.0129)|COAD - Colon adenocarcinoma(84;0.0824)		GCGTCACCTTCTGCTCCTACT	0.637		NA											8	18					0	0	0	0
SFI1	9814	broad.mit.edu	37	22	32009447	32009447	+	Silent	SNP	G	G	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr22:32009447G>T	uc003ale.2	+	26	3066	c.2673G>T	c.(2671-2673)ACG>ACT	p.T891T	SFI1_uc003alf.2_Silent_p.T860T|SFI1_uc003alg.2_Silent_p.T809T|SFI1_uc011alp.1_Silent_p.T797T|SFI1_uc011alq.1_Silent_p.T836T|SFI1_uc003alh.2_RNA|SFI1_uc010gwi.2_RNA|SFI1_uc003ali.2_5'Flank|SFI1_uc003alj.2_5'Flank	NM_001007467	NP_001007468	A8K8P3	SFI1_HUMAN	spindle assembly associated Sfi1 homolog isoform	891					G2/M transition of mitotic cell cycle	centriole|cytosol				central_nervous_system(1)	1						AGGGTGCCACGCGGCTCCTGC	0.682		NA											7	23					2.01e-06	2.24e-06	1	0
DHX30	22907	broad.mit.edu	37	3	47889378	47889378	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr3:47889378A>G	uc003cru.2	+	14	2644	c.2218A>G	c.(2218-2220)ATC>GTC	p.I740V	DHX30_uc003crt.2_Missense_Mutation_p.I701V|MIR1226_hsa-mir-1226|MI0006313_5'Flank	NM_138615	NP_619520	Q7L2E3	DHX30_HUMAN	DEAH (Asp-Glu-Ala-His) box polypeptide 30	740	Helicase C-terminal.					mitochondrial nucleoid	ATP binding|ATP-dependent helicase activity|protein binding|RNA binding			ovary(2)|skin(2)	4				BRCA - Breast invasive adenocarcinoma(193;0.000696)|KIRC - Kidney renal clear cell carcinoma(197;0.00609)|Kidney(197;0.007)		TTCCATCACAATCAATGACAT	0.547		NA											23	39					0	0	0	0
ROBO1	6091	broad.mit.edu	37	3	78987994	78987994	+	Missense_Mutation	SNP	T	T	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr3:78987994T>G	uc003dqe.2	-	4	464	c.256A>C	c.(256-258)ACT>CCT	p.T86P	ROBO1_uc003dqb.2_Missense_Mutation_p.T47P|ROBO1_uc003dqc.2_Missense_Mutation_p.T47P|ROBO1_uc003dqd.2_Missense_Mutation_p.T47P	NM_002941	NP_002932	Q9Y6N7	ROBO1_HUMAN	roundabout 1 isoform a	86	Extracellular (Potential).|Ig-like C2-type 1.				activation of caspase activity|axon midline choice point recognition|cell migration involved in sprouting angiogenesis|chemorepulsion involved in postnatal olfactory bulb interneuron migration|homophilic cell adhesion|negative regulation of chemokine-mediated signaling pathway|negative regulation of mammary gland epithelial cell proliferation|negative regulation of negative chemotaxis|positive regulation of axonogenesis|Roundabout signaling pathway	cell surface|cytoplasm|integral to plasma membrane	axon guidance receptor activity|identical protein binding|LRR domain binding			large_intestine(2)	2		Lung SC(41;0.0257)|Lung NSC(201;0.0439)		LUSC - Lung squamous cell carcinoma(21;0.008)|Epithelial(33;0.00999)|Lung(72;0.0177)|BRCA - Breast invasive adenocarcinoma(55;0.0274)		CAGTTCAAAGTTGCAGGTTCT	0.507		NA											21	55					0	0	0	0
ZPLD1	131368	broad.mit.edu	37	3	102171893	102171893	+	Nonsense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr3:102171893C>A	uc003dvs.1	+	10	1119	c.237C>A	c.(235-237)TGC>TGA	p.C79*	ZPLD1_uc003dvt.1_Nonsense_Mutation_p.C95*|ZPLD1_uc011bhg.1_Nonsense_Mutation_p.C79*	NM_175056	NP_778226	Q8TCW7	ZPLD1_HUMAN	zona pellucida-like domain containing 1	79	ZP.|Extracellular (Potential).					integral to membrane				ovary(2)|skin(2)|central_nervous_system(1)	5						ACTCCCACTGCAGAGGGTTCA	0.453		NA											74	36					4.09e-32	5.03e-32	1	0
WDR5B	54554	broad.mit.edu	37	3	122133906	122133906	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr3:122133906C>T	uc003efa.1	-	1	977	c.470G>A	c.(469-471)GGA>GAA	p.G157E		NM_019069	NP_061942	Q86VZ2	WDR5B_HUMAN	WD repeat domain 5B	157	WD 3.									ovary(3)	3				GBM - Glioblastoma multiforme(114;0.0704)		GAGACACTTTCCTGTTTTCAC	0.403		NA											22	81					0	0	0	0
AHSG	197	broad.mit.edu	37	3	186338468	186338468	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr3:186338468G>A	uc003fqk.3	+	7	934	c.853G>A	c.(853-855)GCA>ACA	p.A285T	AHSG_uc003fql.3_Missense_Mutation_p.A286T|AHSG_uc003fqm.3_Missense_Mutation_p.A284T|AHSG_uc010hyp.2_Missense_Mutation_p.A248T	NM_001622	NP_001613	P02765	FETUA_HUMAN	alpha-2-HS-glycoprotein	285					acute-phase response|negative regulation of bone mineralization|negative regulation of insulin receptor signaling pathway|pinocytosis|positive regulation of phagocytosis|regulation of inflammatory response|skeletal system development	extracellular space	cysteine-type endopeptidase inhibitor activity|protein binding				0	all_cancers(143;3.64e-12)|Ovarian(172;0.0339)		OV - Ovarian serous cystadenocarcinoma(80;3.27e-20)	GBM - Glioblastoma multiforme(93;0.0463)		TCCACTTGGCGCACCTGGACT	0.642		NA											126	83					0	0	0	0
WHSC1	7468	broad.mit.edu	37	4	1902895	1902895	+	Missense_Mutation	SNP	A	A	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:1902895A>T	uc003gdz.3	+	2	690	c.514A>T	c.(514-516)AGC>TGC	p.S172C	WHSC1_uc003geb.3_Missense_Mutation_p.S172C|WHSC1_uc003gec.3_Missense_Mutation_p.S172C|WHSC1_uc003ged.3_Missense_Mutation_p.S172C|WHSC1_uc003gee.3_RNA|WHSC1_uc003gef.3_RNA|WHSC1_uc003gdx.2_Missense_Mutation_p.S172C|WHSC1_uc003gdy.1_Missense_Mutation_p.S172C|WHSC1_uc010icd.1_Missense_Mutation_p.S172C|WHSC1_uc003gea.1_Missense_Mutation_p.S172C|WHSC1_uc010ice.1_Missense_Mutation_p.S172C|WHSC1_uc003geg.1_Missense_Mutation_p.S172C|WHSC1_uc003geh.1_Missense_Mutation_p.S172C	NM_001042424	NP_001035889	O96028	NSD2_HUMAN	Wolf-Hirschhorn syndrome candidate 1 protein	172					anatomical structure morphogenesis|regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|cytoplasm|nuclear membrane|nucleolus	DNA binding|histone-lysine N-methyltransferase activity|zinc ion binding			ovary(3)|lung(3)|skin(2)|pancreas(1)	9		all_epithelial(65;1.34e-05)	OV - Ovarian serous cystadenocarcinoma(23;0.00606)	STAD - Stomach adenocarcinoma(129;0.232)		CAGGAAGAGGAGCATAAAATA	0.438		NA	T	IGH@	MM								12	22					0	0	0	0
SCARB2	950	broad.mit.edu	37	4	77091132	77091132	+	Missense_Mutation	SNP	G	G	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:77091132G>T	uc003hju.1	-	8	1340	c.1001C>A	c.(1000-1002)CCC>CAC	p.P334H	SCARB2_uc011cbu.1_Missense_Mutation_p.P191H	NM_005506	NP_005497	Q14108	SCRB2_HUMAN	scavenger receptor class B, member 2	334	Lumenal (Potential).				cell adhesion|protein targeting to lysosome	integral to plasma membrane|lysosomal lumen|lysosomal membrane|membrane fraction	enzyme binding|receptor activity				0			Lung(101;0.196)			CATAATGATGGGTGCACCTGC	0.413		NA											5	107					4.1e-09	4.66e-09	1	0
SEC31A	22872	broad.mit.edu	37	4	83748771	83748771	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:83748771G>A	uc003hnf.2	-	24	3206	c.3042C>T	c.(3040-3042)TTC>TTT	p.F1014F	SEC31A_uc003hnd.2_Silent_p.F183F|SEC31A_uc003hne.2_Silent_p.F763F|SEC31A_uc011ccl.1_Silent_p.F960F|SEC31A_uc003hnl.2_Silent_p.F861F|SEC31A_uc003hng.2_Silent_p.F999F|SEC31A_uc003hnh.2_Silent_p.F1014F|SEC31A_uc003hni.2_Silent_p.F900F|SEC31A_uc003hnj.2_Silent_p.F975F|SEC31A_uc011ccm.1_Silent_p.F994F|SEC31A_uc011ccn.1_Silent_p.F999F|SEC31A_uc003hnk.2_Silent_p.F975F|SEC31A_uc003hnm.2_Silent_p.F1014F	NM_001077207	NP_001070675	O94979	SC31A_HUMAN	SEC31 homolog A isoform 1	1014	Interaction with PDCD6.|Pro-rich.				COPII vesicle coating|post-translational protein modification|protein N-linked glycosylation via asparagine|protein transport|response to calcium ion	COPII vesicle coat|cytosol|endoplasmic reticulum membrane|perinuclear region of cytoplasm	calcium-dependent protein binding		SEC31A/JAK2(4)|SEC31A/ALK(3)	haematopoietic_and_lymphoid_tissue(4)|soft_tissue(3)|breast(1)	8		Hepatocellular(203;0.114)				CAGGAGGCATGAAGTTTTCAG	0.433		NA											7	181					0	0	0	0
ADH6	130	broad.mit.edu	37	4	100131636	100131636	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:100131636G>A	uc003hup.3	-	4	380	c.286C>T	c.(286-288)CTG>TTG	p.L96L	uc003hum.1_Intron|ADH6_uc003huo.2_Silent_p.L96L|ADH6_uc011cef.1_5'UTR|ADH6_uc010ile.2_Silent_p.L96L	NM_000672	NP_000663	P28332	ADH6_HUMAN	class V alcohol dehydrogenase isoform 2	96					ethanol oxidation|response to ethanol|xenobiotic metabolic process	cytosol	alcohol dehydrogenase (NAD) activity|electron carrier activity|zinc ion binding			ovary(1)|kidney(1)|skin(1)	3				OV - Ovarian serous cystadenocarcinoma(123;3.58e-08)	Abacavir(DB01048)|NADH(DB00157)	CACTGTGGCAGAAAGAGTGTG	0.303		NA											28	80					0	0	0	0
LRBA	987	broad.mit.edu	37	4	151773953	151773953	+	Missense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:151773953C>A	uc010ipj.2	-	23	3383	c.2909G>T	c.(2908-2910)GGA>GTA	p.G970V	LRBA_uc003ilu.3_Missense_Mutation_p.G970V	NM_006726	NP_006717	P50851	LRBA_HUMAN	LPS-responsive vesicle trafficking, beach and	970						endoplasmic reticulum|Golgi apparatus|integral to membrane|lysosome|plasma membrane	protein binding			ovary(3)|breast(3)|skin(1)	7	all_hematologic(180;0.151)					TTGCTGGGATCCTACTGAAAC	0.403		NA											12	41					7.04e-09	7.94e-09	1	0
RAPGEF2	9693	broad.mit.edu	37	4	160266481	160266481	+	Missense_Mutation	SNP	T	T	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:160266481T>G	uc003iqg.3	+	18	3329	c.3019T>G	c.(3019-3021)TTG>GTG	p.L1007V		NM_014247	NP_055062	Q9Y4G8	RPGF2_HUMAN	Rap guanine nucleotide exchange factor 2	1007					cAMP-mediated signaling|MAPKKK cascade|small GTPase mediated signal transduction	integral to plasma membrane|intracellular	calcium ion binding|diacylglycerol binding|Rap GTPase activator activity|Rap guanyl-nucleotide exchange factor activity|signal transducer activity			lung(2)|upper_aerodigestive_tract(1)|skin(1)	4	all_hematologic(180;0.24)			COAD - Colon adenocarcinoma(41;0.0817)		AACCAACACATGTGAGTTTTT	0.463		NA											11	56					0	0	0	0
GLRA3	8001	broad.mit.edu	37	4	175598318	175598318	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr4:175598318C>T	uc003ity.1	-	7	1341	c.838G>A	c.(838-840)GAT>AAT	p.D280N	GLRA3_uc003itz.1_Missense_Mutation_p.D280N	NM_006529	NP_006520	O75311	GLRA3_HUMAN	glycine receptor, alpha 3 isoform a	280					synaptic transmission	cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	extracellular-glycine-gated chloride channel activity|glycine binding|receptor activity|transmitter-gated ion channel activity			ovary(3)	3		Prostate(90;0.00601)|Breast(14;0.0091)|Melanoma(52;0.00959)|Renal(120;0.0183)|all_neural(102;0.0891)|all_hematologic(60;0.107)		all cancers(43;4.99e-18)|Epithelial(43;1.18e-16)|OV - Ovarian serous cystadenocarcinoma(60;5.88e-09)|STAD - Stomach adenocarcinoma(60;0.00442)|GBM - Glioblastoma multiforme(59;0.0102)|LUSC - Lung squamous cell carcinoma(193;0.0421)	Glycine(DB00145)	GGTGCTGCATCCATGTTGATC	0.473		NA											20	38					0	0	0	0
NIPBL	25836	broad.mit.edu	37	5	37008756	37008756	+	Nonsense_Mutation	SNP	T	T	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr5:37008756T>G	uc003jkl.3	+	20	4851	c.4352T>G	c.(4351-4353)TTA>TGA	p.L1451*	NIPBL_uc003jkk.3_Nonsense_Mutation_p.L1451*	NM_133433	NP_597677	Q6KC79	NIPBL_HUMAN	delangin isoform A	1451					brain development|cellular protein localization|cellular response to X-ray|cognition|developmental growth|ear morphogenesis|embryonic arm morphogenesis|embryonic digestive tract morphogenesis|external genitalia morphogenesis|eye morphogenesis|face morphogenesis|gall bladder development|maintenance of mitotic sister chromatid cohesion|metanephros development|negative regulation of transcription from RNA polymerase II promoter|outflow tract morphogenesis|positive regulation of histone deacetylation|regulation of developmental growth|regulation of embryonic development|regulation of hair cycle|response to DNA damage stimulus|sensory perception of sound|uterus morphogenesis	SMC loading complex	chromo shadow domain binding|histone deacetylase binding|protein C-terminus binding|protein N-terminus binding			ovary(4)|lung(2)|large_intestine(1)|breast(1)|kidney(1)	9	all_lung(31;0.000447)|Hepatocellular(1;0.108)		Epithelial(62;0.072)|COAD - Colon adenocarcinoma(61;0.14)|all cancers(62;0.191)|Colorectal(62;0.202)			CATAGGCAGTTAATTTTGGAA	0.279		NA											24	116					0	0	0	0
HEATR7B2	133558	broad.mit.edu	37	5	41008749	41008749	+	Silent	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr5:41008749C>T	uc003jmj.3	-	33	4057	c.3567G>A	c.(3565-3567)GTG>GTA	p.V1189V	HEATR7B2_uc003jmi.3_Silent_p.V744V	NM_173489	NP_775760	Q7Z745	HTRB2_HUMAN	HEAT repeat family member 7B2	1189	HEAT 13.						binding			ovary(6)|central_nervous_system(2)	8						CCTGCTGCATCACATGCCGCC	0.567		NA											34	51					0	0	0	0
YTHDC2	64848	broad.mit.edu	37	5	112868639	112868639	+	Nonsense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr5:112868639C>T	uc003kqn.2	+	5	922	c.739C>T	c.(739-741)CAA>TAA	p.Q247*	YTHDC2_uc010jce.1_Nonsense_Mutation_p.Q247*|YTHDC2_uc010jcf.1_5'UTR	NM_022828	NP_073739	Q9H6S0	YTDC2_HUMAN	YTH domain containing 2	247	Helicase ATP-binding.						ATP binding|ATP-dependent helicase activity|nucleic acid binding			skin(2)|central_nervous_system(1)	3		all_cancers(142;7.69e-05)|all_epithelial(76;6.42e-07)|Colorectal(10;0.00278)|Prostate(80;0.00955)|Ovarian(225;0.0444)|Lung NSC(810;0.143)|all_lung(232;0.163)|Breast(839;0.244)		OV - Ovarian serous cystadenocarcinoma(64;7.2e-08)|Epithelial(69;8.83e-08)|all cancers(49;6.9e-06)|COAD - Colon adenocarcinoma(37;0.0458)|Colorectal(14;0.0594)		ATTTTGTACTCAACCAAGACG	0.378		NA											4	74					0	0	0	0
CEP120	153241	broad.mit.edu	37	5	122729184	122729184	+	Missense_Mutation	SNP	G	G	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr5:122729184G>T	uc003ktk.2	-	7	702	c.620C>A	c.(619-621)CCA>CAA	p.P207Q	CEP120_uc011cwq.1_Missense_Mutation_p.P16Q|CEP120_uc010jcz.1_Missense_Mutation_p.P181Q	NM_153223	NP_694955	Q8N960	CE120_HUMAN	coiled-coil domain containing 100	207						centrosome				ovary(1)	1						CATGGTACATGGAATTAACTA	0.303		NA											20	31					3.67e-16	4.4e-16	1	0
DUSP22	56940	broad.mit.edu	37	6	348127	348127	+	Silent	SNP	G	G	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr6:348127G>A	uc003msx.2	+	6	727	c.288G>A	c.(286-288)GTG>GTA	p.V96V	DUSP22_uc011dhn.1_Silent_p.V96V|DUSP22_uc003msy.1_Silent_p.V53V	NM_020185	NP_064570	Q9NRW4	DUS22_HUMAN	dual specificity phosphatase 22	96	Tyrosine-protein phosphatase.				apoptosis|cell proliferation|inactivation of MAPK activity|multicellular organismal development|positive regulation of JNK cascade|regulation of cell proliferation|transforming growth factor beta receptor signaling pathway	cytoplasm|nucleus	protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			ovary(1)|kidney(1)|central_nervous_system(1)	3	all_hematologic(77;0.228)	Breast(5;0.0249)|all_hematologic(90;0.0489)		OV - Ovarian serous cystadenocarcinoma(45;0.0277)|BRCA - Breast invasive adenocarcinoma(62;0.0669)		CCAGGAGCGTGACACTGGTGA	0.612		NA											50	280					0	0	0	0
PPIL1	51645	broad.mit.edu	37	6	36824426	36824426	+	Silent	SNP	T	T	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr6:36824426T>C	uc003omu.2	-	3	468	c.216A>G	c.(214-216)CGA>CGG	p.R72R		NM_016059	NP_057143	Q9Y3C6	PPIL1_HUMAN	peptidylprolyl isomerase-like 1	72	PPIase cyclophilin-type.				protein folding	catalytic step 2 spliceosome	peptidyl-prolyl cis-trans isomerase activity			ovary(1)	1						ATGCACCACCTCGACCTGCCC	0.458		NA											12	45					0	0	0	0
LRFN2	57497	broad.mit.edu	37	6	40360344	40360344	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr6:40360344C>T	uc003oph.1	-	3	2173	c.1708G>A	c.(1708-1710)GCG>ACG	p.A570T		NM_020737	NP_065788	Q9ULH4	LRFN2_HUMAN	leucine rich repeat and fibronectin type III	570	Cytoplasmic (Potential).					cell junction|integral to membrane|postsynaptic membrane				ovary(2)|skin(1)	3	Ovarian(28;0.0418)|Colorectal(47;0.196)					CTCACGGCCGCTGCCATCTTG	0.677		NA											7	41					0	0	0	0
CUL9	23113	broad.mit.edu	37	6	43189000	43189000	+	Silent	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr6:43189000C>T	uc003ouk.2	+	34	6768	c.6693C>T	c.(6691-6693)CTC>CTT	p.L2231L	CUL9_uc003oul.2_Silent_p.L2203L|CUL9_uc010jyk.2_Silent_p.L1383L|CUL9_uc003oun.2_Silent_p.L26L	NM_015089	NP_055904	Q8IWT3	CUL9_HUMAN	p53-associated parkin-like cytoplasmic protein	2231					ubiquitin-dependent protein catabolic process	cullin-RING ubiquitin ligase complex|cytoplasm	ATP binding|ubiquitin protein ligase binding|zinc ion binding			ovary(5)|lung(3)|skin(2)|breast(1)|central_nervous_system(1)	12						TGGCCAAGCTCATCTCCAAGC	0.612		NA											12	39					0	0	0	0
BEND6	221336	broad.mit.edu	37	6	56857219	56857219	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr6:56857219C>T	uc010kab.2	+	3	750	c.164C>T	c.(163-165)TCC>TTC	p.S55F	BEND6_uc003pdg.2_RNA	NM_152731	NP_689944	Q5SZJ8	BEND6_HUMAN	BEN domain containing 6	55											0						GGTGAAAGCTCCAGTGAGGAT	0.403		NA											55	209					0	0	0	0
FNDC1	84624	broad.mit.edu	37	6	159653481	159653481	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr6:159653481A>G	uc010kjv.2	+	11	2137	c.1937A>G	c.(1936-1938)GAC>GGC	p.D646G	FNDC1_uc010kjw.1_Missense_Mutation_p.D531G	NM_032532	NP_115921	Q4ZHG4	FNDC1_HUMAN	fibronectin type III domain containing 1	646						extracellular region				large_intestine(4)|ovary(3)|central_nervous_system(1)	8		Breast(66;0.000781)|Ovarian(120;0.0308)|Prostate(117;0.195)		OV - Ovarian serous cystadenocarcinoma(65;2.6e-16)|BRCA - Breast invasive adenocarcinoma(81;1.06e-05)		GACTTGGTGGACTCAGACGAA	0.697		NA											9	50					0	0	0	0
PRPS1L1	221823	broad.mit.edu	37	7	18067095	18067095	+	Missense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr7:18067095C>A	uc003stz.2	-	1	392	c.311G>T	c.(310-312)CGG>CTG	p.R104L		NM_175886	NP_787082	P21108	PRPS3_HUMAN	phosphoribosyl pyrophosphate synthetase 1-like	104					nucleoside metabolic process|ribonucleoside monophosphate biosynthetic process		ATP binding|kinase activity|magnesium ion binding|protein homodimerization activity|ribose phosphate diphosphokinase activity			ovary(1)	1	Lung NSC(10;0.0385)|all_lung(11;0.0736)					GATTGGGGACCGGCTCTTATC	0.468		NA											36	110					6.91e-12	8.18e-12	1	0
LAMB4	22798	broad.mit.edu	37	7	107732207	107732207	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr7:107732207T>C	uc010ljo.1	-	14	1649	c.1565A>G	c.(1564-1566)AAT>AGT	p.N522S	LAMB4_uc003vey.2_Missense_Mutation_p.N522S	NM_007356	NP_031382	A4D0S4	LAMB4_HUMAN	laminin, beta 4 precursor	522	Laminin EGF-like 5; truncated.				cell adhesion	basement membrane				ovary(4)|breast(2)|large_intestine(1)|skin(1)	8						ACACTGCCCATTCTTGGGTGA	0.502		NA											18	69					0	0	0	0
CPA5	93979	broad.mit.edu	37	7	130002807	130002807	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr7:130002807C>T	uc010lmd.1	+	10	1339	c.719C>T	c.(718-720)CCT>CTT	p.P240L	CPA5_uc003vps.2_Missense_Mutation_p.P240L|CPA5_uc003vpt.2_Missense_Mutation_p.P240L|CPA5_uc010lme.1_Missense_Mutation_p.P240L|CPA5_uc003vpu.1_Missense_Mutation_p.P240L	NM_001127441	NP_001120913	Q8WXQ8	CBPA5_HUMAN	carboxypeptidase A5 isoform 1	240					proteolysis	extracellular region	metallocarboxypeptidase activity|zinc ion binding			ovary(2)	2	Melanoma(18;0.0435)					GTCACAAACCCTGATGGGTTT	0.502		NA											3	41					0	0	0	0
PXDNL	137902	broad.mit.edu	37	8	52336282	52336282	+	Missense_Mutation	SNP	G	G	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr8:52336282G>T	uc003xqu.3	-	14	1749	c.1648C>A	c.(1648-1650)CAG>AAG	p.Q550K		NM_144651	NP_653252	A1KZ92	PXDNL_HUMAN	peroxidasin homolog-like precursor	550	Ig-like C2-type 4.				hydrogen peroxide catabolic process	extracellular space	heme binding|peroxidase activity			ovary(1)|pancreas(1)	2		all_cancers(86;0.107)|Lung NSC(129;0.00641)|all_epithelial(80;0.00716)|all_lung(136;0.015)				TCAGTAATCTGCACACCTTCC	0.403		NA											12	43					7.04e-09	7.94e-09	1	0
ST18	9705	broad.mit.edu	37	8	53044649	53044649	+	Missense_Mutation	SNP	C	C	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr8:53044649C>G	uc003xqz.2	-	17	2691	c.2535G>C	c.(2533-2535)AAG>AAC	p.K845N	ST18_uc011ldq.1_Missense_Mutation_p.K492N|ST18_uc011ldr.1_Missense_Mutation_p.K810N|ST18_uc011lds.1_Missense_Mutation_p.K750N|ST18_uc003xra.2_Missense_Mutation_p.K845N	NM_014682	NP_055497	O60284	ST18_HUMAN	suppression of tumorigenicity 18	845						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(4)|skin(1)	5		Lung NSC(129;0.131)|all_epithelial(80;0.217)|all_lung(136;0.229)				CCTTCTGTCTCTTGGCAGCCA	0.522		NA											14	60					0	0	0	0
DCAF4L2	138009	broad.mit.edu	37	8	88886149	88886149	+	Missense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr8:88886149C>A	uc003ydz.2	-	1	148	c.51G>T	c.(49-51)AAG>AAT	p.K17N		NM_152418	NP_689631	Q8NA75	DC4L2_HUMAN	WD repeat domain 21C	17										ovary(1)	1						CTCTGACTGTCTTTTTCTGCT	0.537		NA											18	52					3.6e-14	4.28e-14	1	0
UBR5	51366	broad.mit.edu	37	8	103354705	103354705	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr8:103354705T>C	uc003ykr.1	-	9	1127	c.1094A>G	c.(1093-1095)GAT>GGT	p.D365G	UBR5_uc003yks.1_Missense_Mutation_p.D365G	NM_015902	NP_056986	O95071	UBR5_HUMAN	ubiquitin protein ligase E3 component n-recognin	365					cell proliferation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of catenin import into nucleus|positive regulation of protein import into nucleus, translocation|progesterone receptor signaling pathway|protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|response to DNA damage stimulus	nucleus|soluble fraction	protein binding|RNA binding|ubiquitin-ubiquitin ligase activity|zinc ion binding			lung(16)|ovary(4)|large_intestine(3)|breast(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|kidney(1)	28	all_cancers(14;8e-07)|all_epithelial(15;2.18e-08)|Lung NSC(17;2.55e-05)|all_lung(17;8.85e-05)		OV - Ovarian serous cystadenocarcinoma(57;0.000442)			AAATACCTTATCAGGCCACCA	0.408		NA											81	88					0	0	0	0
GPR172A	79581	broad.mit.edu	37	8	145583549	145583549	+	Silent	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr8:145583549C>T	uc003zcc.1	+	3	554	c.397C>T	c.(397-399)CTG>TTG	p.L133L	FBXL6_uc003zbz.2_5'Flank|FBXL6_uc003zca.2_5'Flank|FBXL6_uc003zcb.2_5'Flank|FBXL6_uc010mfx.2_5'Flank|GPR172A_uc003zcd.1_Silent_p.L133L|GPR172A_uc003zce.1_Silent_p.L133L|GPR172A_uc010mfy.1_Silent_p.L133L|GPR172A_uc003zcf.1_Silent_p.L133L|GPR172A_uc011llc.1_Silent_p.L45L	NM_024531	NP_078807	Q9HAB3	RFT3_HUMAN	G protein-coupled receptor 172A precursor	133						integral to plasma membrane	receptor activity|riboflavin transporter activity				0	all_cancers(97;6.64e-12)|all_epithelial(106;2.89e-10)|Lung NSC(106;5.7e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		OV - Ovarian serous cystadenocarcinoma(54;4.43e-40)|Epithelial(56;1.48e-39)|all cancers(56;1.49e-34)|BRCA - Breast invasive adenocarcinoma(115;0.0441)|Colorectal(110;0.055)			TGTCACTTTCCTGCCCTTCTT	0.602		NA											65	281					0	0	0	0
GLIS3	169792	broad.mit.edu	37	9	4117907	4117907	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr9:4117907A>G	uc003zhw.1	-	3	1300	c.1106T>C	c.(1105-1107)GTC>GCC	p.V369A	GLIS3_uc003zhx.1_Missense_Mutation_p.V524A|GLIS3_uc003zic.1_Missense_Mutation_p.V524A|GLIS3_uc003zie.1_Missense_Mutation_p.V524A|GLIS3_uc010mhh.1_Missense_Mutation_p.V399A|GLIS3_uc003zid.1_Missense_Mutation_p.V302A|GLIS3_uc010mhi.1_Missense_Mutation_p.V331A|GLIS3_uc003zif.1_Missense_Mutation_p.V302A|GLIS3_uc003zig.1_Missense_Mutation_p.V368A|GLIS3_uc003zih.1_Missense_Mutation_p.V302A|GLIS3_uc003zhy.1_Missense_Mutation_p.V302A|GLIS3_uc003zhz.1_Missense_Mutation_p.V302A|GLIS3_uc003zib.1_Missense_Mutation_p.V368A|GLIS3_uc010mhg.1_Missense_Mutation_p.V302A	NM_152629	NP_689842	Q8NEA6	GLIS3_HUMAN	GLIS family zinc finger 3 isoform b	369	C2H2-type 1.				negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter		DNA binding|zinc ion binding			ovary(1)	1		Acute lymphoblastic leukemia(2;0.00464)|Breast(48;0.148)		Lung(2;0.00163)|GBM - Glioblastoma multiforme(50;0.00301)|LUSC - Lung squamous cell carcinoma(2;0.0148)		GTCGATGTGGACCTTCTCGAT	0.612		NA											11	73					0	0	0	0
PLIN2	123	broad.mit.edu	37	9	19126190	19126190	+	Missense_Mutation	SNP	C	C	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr9:19126190C>A	uc003zno.2	-	3	327	c.148G>T	c.(148-150)GCA>TCA	p.A50S	PLIN2_uc011lna.1_Missense_Mutation_p.A22S|PLIN2_uc011lnb.1_Missense_Mutation_p.A50S	NM_001122	NP_001113	Q99541	PLIN2_HUMAN	adipose differentiation-related protein	50					cellular lipid metabolic process	endoplasmic reticulum|extracellular region|lipid particle				ovary(2)	2						CCGTTCTCTGCCATCTCACAC	0.517		NA											39	82					1.59e-14	1.9e-14	1	0
SOX3	6658	broad.mit.edu	37	X	139586674	139586674	+	Silent	SNP	C	C	T			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chrX:139586674C>T	uc004fbd.1	-	1	552	c.552G>A	c.(550-552)GAG>GAA	p.E184E		NM_005634	NP_005625	P41225	SOX3_HUMAN	SRY (sex determining region Y)-box 3	184	HMG box.				face development|hypothalamus development|negative regulation of neuron differentiation|pituitary gland development|regulation of transcription, DNA-dependent|sensory organ development|sex determination|transcription, DNA-dependent	nucleus	DNA binding			pancreas(1)	1	Acute lymphoblastic leukemia(192;7.65e-05)					ATGGTCGCTTCTCGGCGTCGG	0.612		NA											4	50					0	0	0	0
CASZ1	54897	broad.mit.edu	37	1	10715709	10715710	+	Frame_Shift_Ins	INS	-	-	A			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr1:10715709_10715710insA	uc001aro.2	-	9	1981_1982	c.1661_1662insT	c.(1660-1662)ATGfs	p.M554fs	CASZ1_uc001arp.1_Frame_Shift_Ins_p.M554fs|CASZ1_uc009vmx.2_Frame_Shift_Ins_p.M578fs	NM_001079843	NP_001073312	Q86V15	CASZ1_HUMAN	castor homolog 1, zinc finger isoform a	554	C2H2-type 1.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|zinc ion binding			skin(1)	1	Ovarian(185;0.203)|all_lung(157;0.204)	Lung NSC(185;4.96e-06)|all_lung(284;1.22e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00212)|Hepatocellular(190;0.00913)|Ovarian(437;0.0229)|Myeloproliferative disorder(586;0.0255)	STAD - Stomach adenocarcinoma(5;0.0224)	UCEC - Uterine corpus endometrioid carcinoma (279;0.0265)|Colorectal(212;3.54e-08)|COAD - Colon adenocarcinoma(227;9.56e-06)|BRCA - Breast invasive adenocarcinoma(304;0.000219)|Kidney(185;0.00142)|KIRC - Kidney renal clear cell carcinoma(229;0.00381)|READ - Rectum adenocarcinoma(331;0.0419)|STAD - Stomach adenocarcinoma(132;0.0623)		GAGGCACCTGCATGCAGTGATA	0.678		NA											18	11	---	---	---	---	NA	NA	NA	NA
POTEG	404785	broad.mit.edu	37	14	19553545	19553545	+	Frame_Shift_Del	DEL	G	G	-			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr14:19553545delG	uc001vuz.1	+	1	181	c.129delG	c.(127-129)GTGfs	p.V43fs	POTEG_uc001vva.1_RNA|POTEG_uc010ahc.1_RNA	NM_001005356	NP_001005356	Q6S5H5	POTEG_HUMAN	POTE ankyrin domain family, member G	43										ovary(1)	1						AGAGCAACGTGGGCACTTCTG	0.602		NA											48	619	---	---	---	---	NA	NA	NA	NA
RGS9	8787	broad.mit.edu	37	17	63223491	63223491	+	Frame_Shift_Del	DEL	A	A	-			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr17:63223491delA	uc002jfe.2	+	19	2101	c.1991delA	c.(1990-1992)GAAfs	p.E664fs	RGS9_uc002jfd.2_Frame_Shift_Del_p.E661fs|RGS9_uc002jff.2_RNA|RGS9_uc002jfg.2_Frame_Shift_Del_p.E435fs	NM_003835	NP_003826	O75916	RGS9_HUMAN	regulator of G-protein signaling 9 isoform 1	664					intracellular signal transduction|negative regulation of signal transduction|regulation of G-protein coupled receptor protein signaling pathway|visual perception	cytoplasm|heterotrimeric G-protein complex	GTPase activator activity|signal transducer activity			ovary(2)|skin(2)	4						CGGGCCACAGAAAAGGAGGTC	0.582		NA											13	36	---	---	---	---	NA	NA	NA	NA
TRIM59	286827	broad.mit.edu	37	3	160156068	160156069	+	Frame_Shift_Del	DEL	TG	TG	-			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr3:160156068_160156069delTG	uc003fdm.2	-	3	1098_1099	c.903_904delCA	c.(901-906)CTCATTfs	p.L301fs	IFT80_uc003fda.2_RNA	NM_173084	NP_775107	Q8IWR1	TRI59_HUMAN	tripartite motif-containing 59	301_302						integral to membrane|intracellular	zinc ion binding				0			Lung(72;0.00334)|LUSC - Lung squamous cell carcinoma(72;0.00523)			ATTTTGGGAATGAGAACGTTCT	0.342		NA											27	110	---	---	---	---	NA	NA	NA	NA
PLEC	5339	broad.mit.edu	37	8	145008578	145008579	+	Frame_Shift_Ins	INS	-	-	G			TCGA-CR-7369-01A-11D-2129-08	TCGA-CR-7369-10A-01D-2129-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	f16a5c08-c9f8-442e-ba13-45681cacda40	1455ebfe-ee2b-43e5-a4bb-993118f35835	g.chr8:145008578_145008579insG	uc003zaf.1	-	11	1657_1658	c.1487_1488insC	c.(1486-1488)CCTfs	p.P496fs	PLEC_uc003zab.1_Frame_Shift_Ins_p.P359fs|PLEC_uc003zac.1_Frame_Shift_Ins_p.P363fs|PLEC_uc003zad.2_Frame_Shift_Ins_p.P359fs|PLEC_uc003zae.1_Frame_Shift_Ins_p.P327fs|PLEC_uc003zag.1_Frame_Shift_Ins_p.P337fs|PLEC_uc003zah.2_Frame_Shift_Ins_p.P345fs|PLEC_uc003zaj.2_Frame_Shift_Ins_p.P386fs	NM_201380	NP_958782	Q15149	PLEC_HUMAN	plectin isoform 1	496	Globular 1.				cellular component disassembly involved in apoptosis|hemidesmosome assembly	cytosol|focal adhesion|hemidesmosome|intermediate filament cytoskeleton|sarcolemma	actin binding|structural constituent of muscle|structural constituent of muscle			large_intestine(2)|ovary(2)|pancreas(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|skin(1)	9						GGTGGTAGCCAGGGGGCACCTT	0.673		NA											35	73	---	---	---	---	NA	NA	NA	NA