Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
GNB1	0	genome.wustl.edu	36	1	1737088	1737088	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	1	1737088	1737088	T	G	SNP	GNB1	NM_002074.2	human	genbank	54_36p	-1	reviewed	missense	c.170	p.K57T	1.000	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40	HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	318	0	0.00	130	134	49.81	227	192	45.71
BLZF1	0	genome.wustl.edu	36	1	167612485	167612485	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	1	167612485	167612485	G	A	SNP	BLZF1	NM_003666.2	human	genbank	54_36p	+1	validated	missense	c.112	p.G38R	0.951	NULL	HMMPfam_DASH_Hsk3	-	no_errors	119	0	0.00	102	118	52.21	10	12	54.55
ADCY3	0	genome.wustl.edu	36	2	24904318	24904318	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	2	24904318	24904318	G	A	SNP	ADCY3	NM_004036.3	human	genbank	54_36p	-1	reviewed	missense	c.2389	p.P797S	0.956	NULL	HMMPfam_Guanylate_cyc,HMMSmart_CYCc,superfamily_A/G_cyclase,PatternScan_GUANYLATE_CYCLASE_1	-	no_errors	153	3	1.91	97	88	47.57	19	14	42.42
ALMS1	0	genome.wustl.edu	36	2	73600435	73600435	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	2	73600435	73600435	C	T	SNP	ALMS1	NM_015120.4	human	genbank	54_36p	+1	reviewed	missense	c.9562	p.L3188F	0.000	NULL	NULL	-	no_errors	137	0	0.00	108	77	40.96	10	14	58.33
TTN	0	genome.wustl.edu	36	2	179150442	179150442	+	Silent	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	2	179150442	179150442	G	A	SNP	TTN	ENST00000375038	human	ensembl	54_36p	-1	known	silent	c.56809	p.L18937	0.869	HMMSmart_SM00409,superfamily_Concanavalin A-like lectins/glucanases,superfamily_WD40 repeat-like,HMMPfam_I-set,superfamily_Immunoglobulin,superfamily_vWA-like,superfamily_Positive stranded ssRNA viruses	HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_IG_MHC,HMMSmart_SM00406,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,HMMPfam_PPAK,PatternScan_PROTEIN_KINASE_TYR,superfamily_Fibronectin type III,superfamily_Concanavalin A-like lectins/glucanases,superfamily_Protein kinase-like (PK-like),superfamily_WD40 repeat-like,HMMPfam_I-set,HMMPfam_ig,HMMPfam_Titin_Z,HMMPfam_Pkinase,PatternScan_FGGY_KINASES_1,PatternScan_PEROXIDASE_1,superfamily_Immunoglobulin,superfamily_vWA-like,superfamily_Positive stranded ssRNA viruses	-	no_errors	158	0	0.00	95	52	35.37	1	0	0.00
RELN	0	genome.wustl.edu	36	7	102938684	102938684	+	Silent	SNP	A	A	G			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	7	102938684	102938684	A	G	SNP	RELN	NM_005045.3	human	genbank	54_36p	-1	reviewed	silent	c.8124	p.N2708	1.000	superfamily_Sialidase	HMMPfam_Reeler,HMMSmart_EGF,superfamily_Sialidase,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_2,superfamily_SSF57196	-	no_errors	117	0	0.00	110	65	36.31	NA	NA	NA
DNAI1	0	genome.wustl.edu	36	9	34496776	34496776	+	Silent	SNP	C	C	T			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	9	34496776	34496776	C	T	SNP	DNAI1	NM_012144.2	human	genbank	54_36p	+1	reviewed	silent	c.1215	p.D405	0.604	HMMSmart_WD40,superfamily_WD40_like	HMMSmart_WD40,superfamily_WD40_like,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	149	0	0.00	92	73	43.71	NA	NA	NA
TNC	0	genome.wustl.edu	36	9	116838243	116838243	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	9	116838243	116838243	T	C	SNP	TNC	NM_002160.2	human	genbank	54_36p	-1	validated	missense	c.5611	p.K1871E	0.977	HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like	HMMPfam_Fibrinogen_C,HMMSmart_FBG,superfamily_Fibrinogen_a/b/g_C,HMMPfam_fn3,HMMSmart_FN3,HMMPfam_EGF,HMMSmart_EGF,superfamily_FN_III-like,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_2	-	no_errors	475	7	1.45	293	262	47.12	NA	NA	NA
CDON	0	genome.wustl.edu	36	11	125376911	125376911	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	11	125376911	125376911	C	T	SNP	CDON	NM_016952.4	human	genbank	54_36p	-1	validated	missense	c.2071	p.V691M	0.118	NULL	HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,HMMPfam_I-set,HMMPfam_ig,superfamily_Immunoglobulin	-	no_errors	552	6	1.07	354	217	37.80	NA	NA	NA
MTUS2	0	genome.wustl.edu	36	13	28498513	28498513	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	13	28498513	28498513	G	A	SNP	KIAA0774	NM_001033602.2	human	genbank	54_36p	+1	validated	missense	c.1708	p.V570M	0.000	NULL	NULL	-	no_errors	294	2	0.68	204	129	38.39	NA	NA	NA
IDH2	0	genome.wustl.edu	36	15	88432938	88432938	+	Missense_Mutation	SNP	C	C	T	rs121913502		TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	15	88432938	88432938	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.419	p.R140Q	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	114	3	2.56	93	70	42.68	111	102	47.89
MIR142	0	genome.wustl.edu	36	17	53763621	53763621	+	RNA	SNP	C	C	G			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	17	53763621	53763621	C	G	SNP	MIRN142	ENST00000384835	human	ensembl	54_36p	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	257	0	0.00	114	39	25.16	78	21	21.21
TCEB3B	0	genome.wustl.edu	36	18	42815075	42815075	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	18	42815075	42815075	C	T	SNP	TCEB3B	NM_016427.2	human	genbank	54_36p	-1	reviewed	missense	c.559	p.A187T	0.000	NULL	HMMSmart_TFS2N,HMMPfam_Elongin_A,HMMPfam_TFIIS	-	no_errors	6	0	0.00	4	8	61.54	NA	NA	NA
LOC728115	0	genome.wustl.edu	36	18	55835205	55835205	+	RNA	SNP	C	C	T			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	18	55835205	55835205	C	T	SNP	LOC728115	XR_038858.1	human	genbank	54_36p	-1	model	rna	NULL	NULL	0.881	-	-	-	pseudogene	207	2	0.96	101	75	42.37	42	0	0.00
FPR1	0	genome.wustl.edu	36	19	56941085	56941085	+	Silent	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	19	56941085	56941085	G	A	SNP	FPR1	NM_002029.3	human	genbank	54_36p	-1	validated	silent	c.975	p.T325	0.875	superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	573	0	0.00	275	178	39.04	44	45	50.56
KIR3DX1	0	genome.wustl.edu	36	19	59738875	59738875	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	19	59738875	59738875	G	A	SNP	KIR3DX1	ENST00000221567	human	ensembl	54_36p	+1	known	missense	c.608	p.R203H	0.000	HMMSmart_SM00409,superfamily_Immunoglobulin	HMMSmart_SM00409,HMMPfam_ig,superfamily_Immunoglobulin	-	no_errors	154	1	0.64	141	120	45.45	1	2	66.67
RUNX1	0	genome.wustl.edu	36	21	35153653	35153653	+	Nonsense_Mutation	SNP	G	G	A			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	21	35153653	35153653	G	A	SNP	RUNX1	NM_001754.2	human	genbank	54_36p	-1	reviewed	nonsense	c.601	p.R201*	1.000	superfamily_p53-like transcription factors,HMMPfam_Runt	superfamily_p53-like transcription factors,HMMPfam_Runt,HMMPfam_RunxI	-	no_errors	190	1	0.52	117	77	39.69	141	152	51.88
RUNX1	0	genome.wustl.edu	36	21	35174809	35174810	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AB-2805-03B-01W-0728-08	TCGA-AB-2805-11B-01W-0728-08	-	-	-	G	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	722c3b06-dbea-4adc-8a7e-49f430211f6e	48eef5ef-c9dc-4c63-b2cd-1cec1dac4098	21	35174809	35174810	-	G	INS	RUNX1	NM_001754.2	human	genbank	54_36p	-1	reviewed	frame_shift_ins	c.423_422	p.A142fs	0.921:1.000	superfamily_p53-like transcription factors,HMMPfam_Runt	superfamily_p53-like transcription factors,HMMPfam_Runt,HMMPfam_RunxI	-	no_errors	91	0	0.00	64	34	34.69	49	25	33.78