Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU STAG2 0 genome.wustl.edu 36 X 123019509 123019509 + Splice_Site SNP G G A TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 X 123019509 123019509 G A SNP STAG2 NM_001042749.1 human genbank 54_36p +1 validated splice_site c.1416+1 e13+1 1.000 - - - no_errors 33 0 0.00 34 16 30.77 1 0 0.00 ELF4 0 genome.wustl.edu 36 X 129032705 129032705 + Missense_Mutation SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 X 129032705 129032705 C T SNP ELF4 NM_001421.1 human genbank 54_36p -1 validated missense c.800 p.R267Q 1.000 HMMPfam_Ets,HMMSmart_ETS,PatternScan_ETS_DOMAIN_2,superfamily_SSF46785 HMMPfam_Ets,HMMSmart_ETS,PatternScan_ETS_DOMAIN_1,PatternScan_ETS_DOMAIN_2,superfamily_SSF46785 - no_errors 43 0 0.00 113 62 35.23 28 93 76.86 THRAP3 0 genome.wustl.edu 36 1 36539747 36539747 + Nonsense_Mutation SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 1 36539747 36539747 C T SNP THRAP3 NM_005119.3 human genbank 54_36p +1 validated nonsense c.2509 p.R837* 0.969 NULL NULL - no_errors 135 0 0.00 128 26 16.46 35 3 7.89 NEB 0 genome.wustl.edu 36 2 152127439 152127439 + Missense_Mutation SNP G G T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 2 152127439 152127439 G T SNP NEB NM_004543.3 human genbank 54_36p -1 reviewed missense c.13720 p.Q4574K 1.000 HMMSmart_SM00227 HMMPfam_Nebulin,HMMSmart_SM00227,HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain - no_errors 129 0 0.00 208 73 25.52 NA NA NA RAP1GDS1 0 genome.wustl.edu 36 4 99483396 99483396 + Missense_Mutation SNP G G A TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 4 99483396 99483396 G A SNP RAP1GDS1 NM_001100426.1 human genbank 54_36p +1 validated missense c.199 p.A67T 1.000 superfamily_ARM repeat HMMPfam_Arm,HMMSmart_SM00185,superfamily_ARM repeat - no_errors 83 0 0.00 134 35 20.59 33 19 36.54 PCDHB12 0 genome.wustl.edu 36 5 140569962 140569962 + Silent SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 5 140569962 140569962 C T SNP PCDHB12 NM_018932.3 human genbank 54_36p +1 reviewed silent c.1299 p.T433 0.000 HMMPfam_Cadherin,HMMSmart_CA,superfamily_Cadherin HMMPfam_Cadherin,HMMSmart_CA,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin - no_errors 30 0 0.00 60 18 22.50 NA NA NA COL12A1 0 genome.wustl.edu 36 6 75917709 75917709 + Missense_Mutation SNP C C A TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 6 75917709 75917709 C A SNP COL12A1 NM_004370.5 human genbank 54_36p -1 reviewed missense c.4015 p.D1339Y 1.000 HMMPfam_VWA,HMMSmart_SM00327,superfamily_vWA-like HMMPfam_VWA,HMMSmart_SM00327,HMMSmart_SM00210,HMMPfam_fn3,HMMSmart_SM00060,HMMPfam_Collagen,superfamily_Fibronectin type III,superfamily_Concanavalin A-like lectins/glucanases,superfamily_vWA-like - no_errors 129 1 0.77 109 23 17.29 NA NA NA TMEM55A 0 genome.wustl.edu 36 8 92077155 92077155 + Missense_Mutation SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 8 92077155 92077155 C T SNP TMEM55A NM_018710.2 human genbank 54_36p -1 validated missense c.700 p.G234R 1.000 HMMPfam_Tmemb_55A HMMPfam_Tmemb_55A - no_errors 49 1 2.00 134 37 21.64 4 7 63.64 PTPN11 0 genome.wustl.edu 36 12 111411292 111411292 + Missense_Mutation SNP A A T rs121918470 TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 A A A T A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 12 111411292 111411292 A T SNP PTPN11 NM_002834.3 human genbank 54_36p +1 reviewed missense c.1529 p.Q510L 1.000 HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_SH2,HMMSmart_SM00252,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II,superfamily_SH2 domain - no_errors 116 0 0.00 335 112 24.78 35 15 30.00 ATG14 0 genome.wustl.edu 36 14 54922339 54922339 + Missense_Mutation SNP G G A TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 14 54922339 54922339 G A SNP KIAA0831 NM_014924.3 human genbank 54_36p -1 predicted missense c.638 p.T213M 0.819 HMMPfam_DUF2355 HMMPfam_DUF2355 - no_errors 117 0 0.00 199 58 22.39 15 15 50.00 HEATR4 0 genome.wustl.edu 36 14 73059207 73059207 + Missense_Mutation SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 14 73059207 73059207 C T SNP HEATR4 NM_203309.1 human genbank 54_36p -1 provisional missense c.262 p.A88T 0.001 NULL HMMPfam_HEAT,superfamily_ARM-type_fold - no_errors 135 0 0.00 239 61 20.20 2 1 33.33 VPS13C 0 genome.wustl.edu 36 15 59969852 59969852 + Missense_Mutation SNP T T C TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 15 59969852 59969852 T C SNP VPS13C NM_020821.1 human genbank 54_36p -1 validated missense c.9145 p.I3049V 1.000 NULL HMMPfam_DUF1162 - no_errors 114 0 0.00 121 36 22.78 58 21 26.58 LRFN3 0 genome.wustl.edu 36 19 41127523 41127523 + Missense_Mutation SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 19 41127523 41127523 C T SNP LRFN3 NM_024509.1 human genbank 54_36p +1 provisional missense c.1649 p.S550L 0.979 NULL HMMSmart_LRRNT,HMMSmart_LRRCT,HMMPfam_LRR_1,HMMSmart_LRR_TYP,HMMSmart_IGc2,HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like,HMMPfam_I-set,superfamily_SSF48726,superfamily_SSF52058 - no_errors 27 0 0.00 72 15 17.24 5 0 0.00 KCNJ6 0 genome.wustl.edu 36 21 38008662 38008662 + Missense_Mutation SNP C C T TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 21 38008662 38008662 C T SNP KCNJ6 NM_002240.2 human genbank 54_36p -1 reviewed missense c.668 p.R223Q 1.000 HMMPfam_IRK,superfamily_Ig_E-set HMMPfam_IRK,superfamily_Ig_E-set,superfamily_SSF81324 - no_errors 42 0 0.00 72 27 27.00 NA NA NA NPM1 0 genome.wustl.edu 36 5 170770148 170770149 + Frame_Shift_Ins INS - - TCTG TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 - - - TCTG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 5 170770148 170770149 - TCTG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.859_860 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA FLT3 0 genome.wustl.edu 36 13 27506262 27506263 + In_Frame_Ins INS - - TCATATTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGTCACCTGTACCATC TCGA-AB-2871-03A-01W-0732-08 TCGA-AB-2871-11A-01W-0732-08 - - - TCATATTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGTCACCTGTACCATC - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 3e8efa46-6045-4be1-b41b-e7b98f165d24 6c7c2063-37fc-45fc-8401-6169345b8c05 13 27506262 27506263 - TCATATTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGTCACCTGTACCATC INS FLT3 NM_004119.2 human genbank 54_36p -1 reviewed in_frame_ins c.1794_1793 p.599in_frame_insMVQVTGSSDNEYFYVDFREYE 0.789:0.821 superfamily_Kinase_like HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726 - no_errors NA NA NA NA NA NA NA NA NA