Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
BRWD3	0	genome.wustl.edu	36	X	79875620	79875620	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	X	79875620	79875620	T	C	SNP	BRWD3	NM_153252.3	human	genbank	54_36p	-1	validated	missense	c.1118	p.N373S	1.000	HMMSmart_SM00320,superfamily_YVTN repeat-like/Quinoprotein amine dehydrogenase,HMMPfam_WD40	HMMPfam_Bromodomain,HMMSmart_SM00297,superfamily_Bromodomain,HMMSmart_SM00320,superfamily_YVTN repeat-like/Quinoprotein amine dehydrogenase,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	151	15	8.98	47	37	44.05	0	31	96.88
NRAS	0	genome.wustl.edu	36	1	115060270	115060270	+	Missense_Mutation	SNP	C	C	T	rs121913237		TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	1	115060270	115060270	C	T	SNP	NRAS	NM_002524.3	human	genbank	54_36p	-1	reviewed	missense	c.35	p.G12D	1.000	HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	123	10	7.41	54	41	42.71	29	21	42.00
TMEM18	0	genome.wustl.edu	36	2	667320	667320	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	2	667320	667320	G	C	SNP	TMEM18	NM_152834.2	human	genbank	54_36p	-1	validated	missense	c.26	p.S9C	0.002	NULL	NULL	-	no_errors	44	4	8.16	23	20	46.51	12	11	47.83
DNMT3A	0	genome.wustl.edu	36	2	25317033	25317033	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	2	25317033	25317033	G	A	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2153	p.P718L	1.000	HMMPfam_DNA_methylase,superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	28	5	15.15	1	14	93.33	1	132	98.51
PRKD3	0	genome.wustl.edu	36	2	37333846	37333846	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	2	37333846	37333846	T	C	SNP	PRKD3	NM_005813.3	human	genbank	54_36p	-1	reviewed	missense	c.2651	p.D884G	1.000	NULL	HMMSmart_SM00219,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_C1_1,HMMSmart_SM00109,PatternScan_ZF_DAG_PE_1,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase,superfamily_PH domain-like,superfamily_Cysteine-rich domain	-	no_errors	122	10	7.46	76	78	50.65	42	45	51.72
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	2	208821358	208821358	G	A	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132C	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	56	10	14.49	22	20	47.62	35	54	60.67
TMEM108	0	genome.wustl.edu	36	3	134597446	134597446	+	Missense_Mutation	SNP	A	A	T			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	3	134597446	134597446	A	T	SNP	TMEM108	NM_023943.1	human	genbank	54_36p	+1	validated	missense	c.1654	p.T552S	1.000	NULL	PatternScan_TONB_DEPENDENT_REC_1	-	no_errors	48	3	5.88	19	17	47.22	NA	NA	NA
LAMA2	0	genome.wustl.edu	36	6	129746059	129746059	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	6	129746059	129746059	C	T	SNP	LAMA2	NM_000426.3	human	genbank	54_36p	+1	reviewed	missense	c.5059	p.R1687W	1.000	superfamily_ConA_like_lec_gl,HMMPfam_Laminin_I	HMMPfam_Laminin_B,HMMSmart_LamG,HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,PatternScan_EGF_LAM_1,HMMPfam_Laminin_N,HMMSmart_LamNT,superfamily_Gal_bind_like,superfamily_ConA_like_lec_gl,HMMPfam_Laminin_I,HMMPfam_Laminin_II,HMMPfam_Laminin_G_1,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,HMMSmart_LamB,superfamily_SSF56399,superfamily_SSF57196	-	no_errors	55	3	5.17	30	21	40.38	NA	NA	NA
EZH2	0	genome.wustl.edu	36	7	148137376	148137376	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	7	148137376	148137376	C	T	SNP	EZH2	NM_004456.3	human	genbank	54_36p	-1	reviewed	missense	c.2069	p.R690H	1.000	HMMPfam_SET,HMMSmart_SET,superfamily_SSF82199	HMMSmart_SANT,HMMPfam_SET,HMMSmart_SET,superfamily_SSF82199	-	no_errors	84	10	10.64	3	42	93.33	1	28	96.55
DYNC2H1	0	genome.wustl.edu	36	11	102544755	102544755	+	Silent	SNP	T	T	C			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	11	102544755	102544755	T	C	SNP	DYNC2H1	NM_001080463.1	human	genbank	54_36p	+1	provisional	silent	c.4824	p.D1608	0.999	NULL	HMMSmart_SM00382,HMMPfam_Dynein_heavy,HMMPfam_AAA_5,HMMPfam_DHC_N1,HMMPfam_DHC_N2,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	60	7	10.45	41	34	45.33	0	1	100.00
ACAT1	0	genome.wustl.edu	36	11	107514954	107514954	+	Silent	SNP	T	T	G			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	11	107514954	107514954	T	G	SNP	ACAT1	NM_000019.3	human	genbank	54_36p	+1	reviewed	silent	c.555	p.T185	0.739	HMMPfam_Thiolase_N,superfamily_Thiolase-like	HMMPfam_Thiolase_N,HMMPfam_Thiolase_C,PatternScan_THIOLASE_1,PatternScan_THIOLASE_3,PatternScan_THIOLASE_2,superfamily_Thiolase-like	-	no_errors	98	7	6.60	53	51	49.04	62	42	40.38
FGD6	0	genome.wustl.edu	36	12	94128011	94128011	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	12	94128011	94128011	C	T	SNP	FGD6	NM_018351.3	human	genbank	54_36p	-1	validated	missense	c.1180	p.A394T	0.000	NULL	HMMPfam_RhoGEF,HMMSmart_SM00325,superfamily_DBL homology domain (DH-domain),HMMPfam_FYVE,HMMSmart_SM00064,HMMPfam_PH,HMMSmart_SM00233,superfamily_FYVE/PHD zinc finger,PatternScan_C_TYPE_LECTIN_1,superfamily_PH domain-like	-	no_errors	94	15	13.64	85	63	42.57	4	4	50.00
BDKRB2	0	genome.wustl.edu	36	14	95776976	95776976	+	Silent	SNP	G	G	A			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	14	95776976	95776976	G	A	SNP	BDKRB2	NM_000623.3	human	genbank	54_36p	+1	reviewed	silent	c.558	p.L186	0.046	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	21	1	4.55	14	25	62.50	NA	NA	NA
CES1P1	0	genome.wustl.edu	36	16	54358799	54358799	+	RNA	SNP	G	G	A			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	16	54358799	54358799	G	A	SNP	CES4	NR_003276.2	human	genbank	54_36p	+1	validated	rna	NULL	NULL	0.000	-	-	-	pseudogene	98	9	8.33	76	62	44.93	NA	NA	NA
ABCC3	0	genome.wustl.edu	36	17	46115973	46115973	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	17	46115973	46115973	C	T	SNP	ABCC3	NM_003786.1	human	genbank	54_36p	+1	reviewed	missense	c.3811	p.P1271S	1.000	superfamily_Multidrug resistance ABC transporter MsbA N-terminal domain	HMMPfam_ABC_membrane,HMMPfam_ABC_tran,HMMSmart_SM00382,superfamily_Multidrug resistance ABC transporter MsbA N-terminal domain,PatternScan_ABC_TRANSPORTER_1,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	95	9	8.65	17	22	56.41	NA	NA	NA
CYP4F2	0	genome.wustl.edu	36	19	15861324	15861324	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2887-03A-01W-0732-08	TCGA-AB-2887-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	63b061fa-a51b-4160-8cf6-cb6d17bd5c5a	191233e7-e123-4253-922e-983ab11690b8	19	15861324	15861324	C	T	SNP	CYP4F2	NM_001082.3	human	genbank	54_36p	-1	reviewed	missense	c.827	p.R276H	0.027	HMMPfam_p450,superfamily_Cytochrome_P450	HMMPfam_p450,superfamily_Cytochrome_P450,PatternScan_CYTOCHROME_P450	-	no_errors	71	9	11.25	40	49	55.06	1	0	0.00