Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
RBMS1	0	genome.wustl.edu	36	2	160842078	160842078	+	Silent	SNP	C	C	T			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	2	160842078	160842078	C	T	SNP	RBMS1	NM_016836.4	human	genbank	54_36p	-1	reviewed	silent	c.1125	p.T375	0.019	NULL	HMMPfam_RRM_1,HMMSmart_SM00360,superfamily_RNA-binding domain RBD	-	no_errors	120	10	7.63	60	60	50.00	8	9	52.94
LOC100131482	0	genome.wustl.edu	36	2	180387594	180387594	+	Silent	SNP	T	T	C			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	2	180387594	180387594	T	C	SNP	LOC100131482	XM_001722616.1	human	genbank	54_36p	+1	model	silent	c.372	p.N124	1.000	HMMPfam_DIM1,superfamily_Thioredoxin-like	HMMPfam_DIM1,superfamily_Thioredoxin-like	-	no_errors	232	5	2.10	172	133	43.61	NA	NA	NA
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	2	208821358	208821358	G	A	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132C	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	114	5	4.20	63	59	48.36	81	70	46.36
HECW1	0	genome.wustl.edu	36	7	43558414	43558414	+	Silent	SNP	G	G	A			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	7	43558414	43558414	G	A	SNP	HECW1	NM_015052.3	human	genbank	54_36p	+1	validated	silent	c.4464	p.A1488	0.315	HMMPfam_HECT,HMMSmart_HECTc,superfamily_HECT	HMMPfam_C2,HMMSmart_C2,HMMPfam_HECT,HMMSmart_HECTc,superfamily_HECT,HMMPfam_WW,HMMSmart_WW,PatternScan_WW_DOMAIN_1,superfamily_WW_Rsp5_WWP,superfamily_C2_CaLB	-	no_errors	297	18	5.61	177	142	44.10	NA	NA	NA
OR52E8	0	genome.wustl.edu	36	11	5835331	5835331	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	11	5835331	5835331	T	C	SNP	OR52E8	NM_001005168.1	human	genbank	54_36p	-1	provisional	missense	c.178	p.S60G	0.746	HMMPfam_7tm_1,superfamily_SSF81321	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_SSF81321	-	no_errors	166	8	4.60	121	86	41.55	NA	NA	NA
AGBL2	0	genome.wustl.edu	36	11	47668631	47668631	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	11	47668631	47668631	C	A	SNP	AGBL2	NM_024783.2	human	genbank	54_36p	-1	validated	missense	c.1204	p.D402Y	0.729	superfamily_Zn-dependent exopeptidases	HMMPfam_Peptidase_M14,superfamily_Zn-dependent exopeptidases	-	no_errors	545	18	3.18	197	165	45.08	3	0	0.00
LYRM5	0	genome.wustl.edu	36	12	25248491	25248491	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	12	25248491	25248491	C	T	SNP	LYRM5	NM_001001660.2	human	genbank	54_36p	+1	validated	missense	c.251	p.S84L	0.130	NULL	HMMPfam_Complex1_LYR	-	no_errors	255	8	3.02	179	94	34.06	22	18	45.00
RYR3	0	genome.wustl.edu	36	15	31910538	31910538	+	Missense_Mutation	SNP	T	T	A			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	15	31910538	31910538	T	A	SNP	RYR3	NM_001036.3	human	genbank	54_36p	+1	validated	missense	c.11417	p.L3806Q	0.980	HMMPfam_RIH_assoc	HMMPfam_RYDR_ITPR,HMMPfam_RyR,HMMPfam_MIR,superfamily_MIR domain (Pfam 02815),HMMPfam_SPRY,HMMPfam_Ion_trans,HMMPfam_RR_TM4-6,HMMPfam_RIH_assoc,HMMPfam_Ins145_P3_rec,HMMSmart_SM00472,HMMPfam_efhand,HMMSmart_SM00449,superfamily_EF-hand	-	no_errors	162	19	10.38	110	107	48.64	NA	NA	NA
C16orf57	0	genome.wustl.edu	36	16	56608774	56608774	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2901-03A-01W-0733-08	TCGA-AB-2901-11A-01W-0732-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	bac6a6d2-8c40-43cd-ab4c-16d3f8a06eb6	22f3f166-41a7-4058-a315-d72e1d7becd6	16	56608774	56608774	C	G	SNP	C16orf57	NM_024598.2	human	genbank	54_36p	+1	validated	missense	c.539	p.A180G	0.769	HMMPfam_HVSL	HMMPfam_HVSL	-	no_errors	434	18	3.90	116	90	43.69	31	24	43.64