Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU MT-CO2 0 genome.wustl.edu 36 MT 7782 7782 + Missense_Mutation SNP A A G TCGA-AB-2903-03A-01W-0761-09 TCGA-AB-2903-11A-01W-0732-08 A A A G A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq dfa1b9d8-2350-47c4-8e24-999a0fdc367a 5948c190-d1f4-46e3-8797-fde42703d879 MT 7782 7782 A G SNP MT-CO2 ENST00000361739 human ensembl 54_36p +1 known missense c.196 p.T66A NULL HMMPfam_COX2_TM,superfamily_Cytochrome^^_^^c^^_^^oxidase^^_^^subunit^^_^^II-like^^_^^transmembrane^^_^^region PatternScan_COX2,HMMPfam_COX2,superfamily_Cupredoxins,HMMPfam_COX2_TM,superfamily_Cytochrome^^_^^c^^_^^oxidase^^_^^subunit^^_^^II-like^^_^^transmembrane^^_^^region - no_errors 1525 118 7.09 1244 417 24.94 NA NA NA AP1S3 0 genome.wustl.edu 36 2 224348892 224348892 + Silent SNP G G A TCGA-AB-2903-03A-01W-0761-09 TCGA-AB-2903-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq dfa1b9d8-2350-47c4-8e24-999a0fdc367a 5948c190-d1f4-46e3-8797-fde42703d879 2 224348892 224348892 G A SNP AP1S3 NM_001039569.1 human genbank 54_36p -1 validated silent c.261 p.Y87 1.000 HMMPfam_Clat_adaptor_s,superfamily_SNARE-like HMMPfam_Clat_adaptor_s,PatternScan_CLAT_ADAPTOR_S,superfamily_SNARE-like - no_errors 389 39 9.07 330 113 25.17 6 2 25.00 NPM1 0 genome.wustl.edu 36 5 170770148 170770149 + Frame_Shift_Ins INS - - TCTG TCGA-AB-2903-03A-01W-0761-09 TCGA-AB-2903-11A-01W-0732-08 - - - TCTG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq dfa1b9d8-2350-47c4-8e24-999a0fdc367a 5948c190-d1f4-46e3-8797-fde42703d879 5 170770148 170770149 - TCTG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.859_860 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA