Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
WLS	0	genome.wustl.edu	36	1	68432309	68432309	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	1	68432309	68432309	G	C	SNP	GPR177	NM_001002292.1	human	genbank	54_36p	-1	validated	missense	c.290	p.P97R	0.975	NULL	HMMPfam_DUF1171	-	no_errors	274	5	1.79	198	88	30.66	NA	NA	NA
TTN	0	genome.wustl.edu	36	2	179355792	179355792	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	2	179355792	179355792	T	C	SNP	TTN	NM_133379.3	human	genbank	54_36p	-1	reviewed	missense	c.3086	p.Y1029C	1.000	HMMPfam_I-set,superfamily_SSF48726	PatternScan_THIOL_PROTEASE_HIS,PatternScan_IG_MHC,HMMSmart_IGc2,HMMSmart_IG,HMMPfam_I-set,HMMPfam_ig,HMMPfam_Titin_Z,superfamily_SSF48726	-	no_errors	225	2	0.88	183	71	27.95	NA	NA	NA
FRZB	0	genome.wustl.edu	36	2	183439321	183439321	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	2	183439321	183439321	T	C	SNP	FRZB	NM_001463.2	human	genbank	54_36p	-1	validated	missense	c.205	p.I69V	1.000	superfamily_Frizzled cysteine-rich domain,HMMPfam_Fz,HMMSmart_SM00063	superfamily_Frizzled cysteine-rich domain,superfamily_TIMP-like,HMMPfam_NTR,HMMSmart_SM00643,HMMPfam_Fz,HMMSmart_SM00063	-	no_errors	744	7	0.93	205	92	30.87	NA	NA	NA
ALS2CR11	0	genome.wustl.edu	36	2	202109171	202109171	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	2	202109171	202109171	C	T	SNP	ALS2CR11	NM_152525.4	human	genbank	54_36p	-1	validated	missense	c.1324	p.V442M	0.000	NULL	NULL	-	no_errors	277	4	1.42	266	149	35.65	NA	NA	NA
RBM46	0	genome.wustl.edu	36	4	155968543	155968543	+	Silent	SNP	C	C	T			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	4	155968543	155968543	C	T	SNP	RBM46	NM_144979.3	human	genbank	54_36p	+1	validated	silent	c.1476	p.S492	1.000	NULL	HMMPfam_RRM_1,HMMSmart_RRM,superfamily_SSF54928	-	no_errors	341	1	0.29	167	89	34.50	NA	NA	NA
PCDHB1	0	genome.wustl.edu	36	5	140413003	140413003	+	Silent	SNP	C	C	A			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	5	140413003	140413003	C	A	SNP	PCDHB1	NM_013340.2	human	genbank	54_36p	+1	reviewed	silent	c.1764	p.T588	1.000	HMMPfam_Cadherin,superfamily_Cadherin	HMMPfam_Cadherin,HMMSmart_CA,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin	-	no_errors	240	2	0.82	136	66	32.67	NA	NA	NA
RCAN2	0	genome.wustl.edu	36	6	46298840	46298840	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	6	46298840	46298840	G	C	SNP	RCAN2	NM_005822.2	human	genbank	54_36p	-1	validated	missense	c.591	p.N197K	1.000	NULL	HMMPfam_Calcipressin	-	no_errors	258	2	0.77	218	63	22.26	NA	NA	NA
CLVS2	0	genome.wustl.edu	36	6	123426552	123426552	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	6	123426552	123426552	C	T	SNP	RLBP1L2	NM_001010852.2	human	genbank	54_36p	+1	provisional	missense	c.931	p.R311C	1.000	NULL	HMMPfam_CRAL_TRIO,HMMSmart_SM00516,superfamily_CRAL/TRIO domain,PatternScan_SUGAR_TRANSPORT_1,HMMPfam_CRAL_TRIO_N,superfamily_CRAL/TRIO N-terminal domain	-	no_errors	327	3	0.91	471	143	23.18	NA	NA	NA
FKTN	0	genome.wustl.edu	36	9	107403451	107403451	+	Splice_Site	SNP	G	G	T			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	9	107403451	107403451	G	T	SNP	FKTN	NM_001079802.1	human	genbank	54_36p	+1	reviewed	splice_site	c.369+1	e3+1	1.000	-	-	-	no_errors	162	1	0.61	314	102	24.52	NA	NA	NA
GDF10	0	genome.wustl.edu	36	10	48049363	48049363	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	10	48049363	48049363	G	A	SNP	GDF10	NM_004962.2	human	genbank	54_36p	-1	reviewed	missense	c.529	p.L177F	0.005	NULL	HMMPfam_TGF_beta,HMMSmart_SM00204,PatternScan_TGF_BETA_1,superfamily_Cystine-knot cytokines	-	no_errors	85	1	1.16	30	24	44.44	NA	NA	NA
IDH2	0	genome.wustl.edu	36	15	88432938	88432938	+	Missense_Mutation	SNP	C	C	T	rs121913502		TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	15	88432938	88432938	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.419	p.R140Q	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	50	1	1.92	49	22	30.99	NA	NA	NA
ZNF236	0	genome.wustl.edu	36	18	72709732	72709732	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	18	72709732	72709732	C	G	SNP	ZNF236	NM_007345.3	human	genbank	54_36p	+1	validated	missense	c.461	p.A154G	0.953	HMMPfam_zf-C2H2,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	308	2	0.65	154	71	31.14	NA	NA	NA
ZNF324B	0	genome.wustl.edu	36	19	63659414	63659414	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	19	63659414	63659414	G	A	SNP	ZNF324B	NM_207395.2	human	genbank	54_36p	+1	validated	missense	c.1291	p.G431S	0.719	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	207	6	2.82	54	21	28.00	NA	NA	NA
ASXL1	0	genome.wustl.edu	36	20	30488419	30488419	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	20	30488419	30488419	C	T	SNP	ASXL1	NM_015338.4	human	genbank	54_36p	+1	reviewed	nonsense	c.4243	p.R1415*	1.000	NULL	NULL	-	no_errors	86	0	0.00	35	19	35.19	NA	NA	NA
RUNX1	0	genome.wustl.edu	36	21	35153747	35153747	+	Splice_Site	SNP	T	T	G			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	21	35153747	35153747	T	G	SNP	RUNX1	NM_001754.2	human	genbank	54_36p	-1	reviewed	splice_site	c.509-2	e5-2	1.000	-	-	-	no_errors	128	0	0.00	90	72	44.44	NA	NA	NA
UQCR10	0	genome.wustl.edu	36	22	28493401	28493401	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2907-03A-01D-0739-09	TCGA-AB-2907-11A-01D-0739-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0f0881a0-c9bc-4636-a99f-36551df20deb	a29c2d2b-1e78-443f-aac3-def013f368ca	22	28493401	28493401	C	A	SNP	UCRC	NM_013387.1	human	genbank	54_36p	+1	validated	missense	c.14	p.T5K	0.003	superfamily_Ubiquinol_cytC_Reductase_QCR9	HMMPfam_UCR_UQCRX_QCR9,superfamily_Ubiquinol_cytC_Reductase_QCR9	-	no_errors	141	1	0.70	75	40	34.78	NA	NA	NA