Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
ENSG00000210184	0	genome.wustl.edu	36	MT	12256	12256	+	RNA	SNP	T	T	G			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	MT	12256	12256	T	G	SNP	ENSG00000210184	ENST00000387449	human	ensembl	54_36p	+1	novel	rna	NULL	NULL	NULL	-	-	-	no_errors	2884	26	0.89	1398	1350	48.56	NA	NA	NA
MAP7D2	0	genome.wustl.edu	36	X	19943346	19943346	+	Silent	SNP	C	C	T			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	X	19943346	19943346	C	T	SNP	MAP7D2	NM_152780.2	human	genbank	54_36p	-1	provisional	silent	c.1542	p.K514	0.996	HMMPfam_MAP7	HMMPfam_MAP7	-	no_errors	130	0	0.00	141	117	45.35	NA	NA	NA
RBBP4	0	genome.wustl.edu	36	1	32910659	32910659	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	1	32910659	32910659	G	A	SNP	RBBP4	NM_005610.1	human	genbank	54_36p	+1	reviewed	missense	c.988	p.E330K	1.000	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40	HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	153	0	0.00	110	20	15.38	68	20	22.73
MYBPHL	0	genome.wustl.edu	36	1	109640989	109640989	+	Silent	SNP	G	G	A			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	1	109640989	109640989	G	A	SNP	MYBPHL	NM_001010985.2	human	genbank	54_36p	-1	validated	silent	c.669	p.N223	0.996	HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III	HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,HMMPfam_I-set,superfamily_Immunoglobulin	-	no_errors	120	0	0.00	82	85	49.42	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25321690	25321690	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	2	25321690	25321690	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.1490	p.C497Y	1.000	NULL	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	23	0	0.00	17	26	60.47	15	49	76.56
RIF1	0	genome.wustl.edu	36	2	152027712	152027712	+	Missense_Mutation	SNP	T	T	A			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	2	152027712	152027712	T	A	SNP	RIF1	NM_018151.3	human	genbank	54_36p	+1	validated	missense	c.3432	p.H1144Q	0.057	superfamily_ARM repeat	superfamily_ARM repeat,PatternScan_ABC_TRANSPORTER_1	-	no_errors	60	1	1.64	69	79	52.67	33	35	51.47
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	2	208821358	208821358	G	A	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132C	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	43	0	0.00	64	49	42.98	34	38	52.78
UBP1	0	genome.wustl.edu	36	3	33425280	33425280	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	3	33425280	33425280	G	T	SNP	UBP1	NM_014517.1	human	genbank	54_36p	-1	validated	missense	c.833	p.P278H	1.000	NULL	HMMPfam_CP2,superfamily_SAM/Pointed domain	-	no_errors	218	2	0.90	169	155	47.40	36	23	38.98
GRIK2	0	genome.wustl.edu	36	6	102622973	102622973	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	6	102622973	102622973	G	A	SNP	GRIK2	NM_021956.3	human	genbank	54_36p	+1	reviewed	missense	c.2621	p.R874Q	1.000	NULL	HMMPfam_Lig_chan,HMMSmart_SM00079,HMMPfam_ANF_receptor,HMMPfam_Lig_chan-Glu_bd,superfamily_Periplasmic binding protein-like I,superfamily_Periplasmic binding protein-like II	-	no_errors	165	2	1.20	191	37	16.23	NA	NA	NA
MPDZ	0	genome.wustl.edu	36	9	13214490	13214490	+	Silent	SNP	C	C	T			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	9	13214490	13214490	C	T	SNP	MPDZ	NM_003829.3	human	genbank	54_36p	-1	validated	silent	c.276	p.S92	0.705	NULL	HMMPfam_PDZ,HMMSmart_SM00228,superfamily_PDZ domain-like,HMMPfam_L27_2,superfamily_L27 domain	-	no_errors	127	1	0.78	130	88	40.37	1	0	0.00
WT1	0	genome.wustl.edu	36	11	32370133	32370133	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	11	32370133	32370133	G	A	SNP	WT1	NM_024426.3	human	genbank	54_36p	-1	reviewed	missense	c.1393	p.H465Y	1.000	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_WT1,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	86	0	0.00	119	41	25.47	62	12	16.22
FAM48A	0	genome.wustl.edu	36	13	36489471	36489471	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	13	36489471	36489471	G	C	SNP	FAM48A	NM_001014286.2	human	genbank	54_36p	-1	validated	missense	c.1903	p.L635V	1.000	NULL	NULL	-	no_errors	115	1	0.86	102	98	48.76	46	48	51.06
IGLV3-27	0	genome.wustl.edu	36	22	21341172	21341172	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	22	21341172	21341172	C	T	SNP	IGLV3-27	ENST00000390304	human	ensembl	54_36p	+1	known	nonsense	c.235	p.R79*	0.399	HMMSmart_SM00406,HMMSmart_SM00409,HMMPfam_V-set,superfamily_Immunoglobulin	HMMSmart_SM00406,HMMSmart_SM00409,HMMPfam_V-set,superfamily_Immunoglobulin	-	no_stop_codon:bad_bp_length_for_coding_region	25	1	3.85	27	34	55.74	20	0	0.00
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2919-03A-01W-0745-08	TCGA-AB-2919-11A-01W-0745-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	296585d2-3c3a-42ae-a565-250ca150353b	8e5dd512-6e0d-4dfd-8e74-d66bff89b042	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA