Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
SLC45A2	0	genome.wustl.edu	36	5	34020284	34020284	+	Silent	SNP	C	C	T			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	5	34020284	34020284	C	T	SNP	SLC45A2	NM_016180.2	human	genbank	54_36p	-1	reviewed	silent	c.162	p.A54	0.858	superfamily_MFS general substrate transporter	superfamily_MFS general substrate transporter	-	no_errors	139	11	7.28	39	34	45.95	NA	NA	NA
PPAP2A	0	genome.wustl.edu	36	5	54757513	54757513	+	Missense_Mutation	SNP	A	A	C			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	5	54757513	54757513	A	C	SNP	PPAP2A	NM_176895.2	human	genbank	54_36p	-1	reviewed	missense	c.664	p.Y222D	1.000	HMMPfam_PAP2,HMMSmart_SM00014,superfamily_Acid phosphatase/Vanadium-dependent haloperoxidase	HMMPfam_PAP2,HMMSmart_SM00014,superfamily_Acid phosphatase/Vanadium-dependent haloperoxidase	-	no_errors	260	9	3.33	61	68	51.91	2	6	75.00
DMRT3	0	genome.wustl.edu	36	9	980602	980602	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	9	980602	980602	C	G	SNP	DMRT3	NM_021240.2	human	genbank	54_36p	+1	validated	missense	c.1016	p.T339R	0.998	NULL	HMMPfam_DM,HMMSmart_DM,PatternScan_DM_1,superfamily_DM_DNA_bd,HMMPfam_DMA	-	no_errors	130	8	5.80	21	10	32.26	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27490642	27490642	+	Missense_Mutation	SNP	C	C	A	rs121913488		TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	13	27490642	27490642	C	A	SNP	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	missense	c.2503	p.D835Y	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	96	15	13.51	34	22	38.60	311	249	44.46
DIO2	0	genome.wustl.edu	36	14	79739147	79739147	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	14	79739147	79739147	C	T	SNP	DIO2	NM_001007023.4	human	genbank	54_36p	-1	reviewed	missense	c.568	p.A190T	1.000	HMMPfam_T4_deiodinase	HMMPfam_T4_deiodinase	-	pseudogene	113	13	10.24	30	32	50.79	1	0	0.00
BCMO1	0	genome.wustl.edu	36	16	79850793	79850793	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	16	79850793	79850793	T	G	SNP	BCMO1	NM_017429.2	human	genbank	54_36p	+1	reviewed	missense	c.205	p.Y69D	0.938	HMMPfam_RPE65	HMMPfam_RPE65	-	no_errors	191	23	10.75	30	28	47.46	NA	NA	NA
SNORD3A	0	genome.wustl.edu	36	17	19032024	19032024	+	RNA	SNP	C	C	T			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	17	19032024	19032024	C	T	SNP	SNORD3A	ENST00000365494	human	ensembl	54_36p	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	379	21	5.25	76	14	15.38	50	7	12.28
KRT27	0	genome.wustl.edu	36	17	36192063	36192063	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	17	36192063	36192063	G	A	SNP	KRT27	NM_181537.3	human	genbank	54_36p	-1	validated	missense	c.209	p.A70V	0.000	NULL	HMMPfam_Filament	-	no_errors	148	9	5.70	35	35	50.00	NA	NA	NA
PHLPP1	0	genome.wustl.edu	36	18	58648409	58648409	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	18	58648409	58648409	G	C	SNP	PHLPP	NM_194449.1	human	genbank	54_36p	+1	validated	missense	c.202	p.G68R	1.000	HMMPfam_PH	HMMPfam_LRR_1,HMMPfam_PH,HMMSmart_SM00332,superfamily_Protein serine/threonine phosphatase 2C catalytic domain,HMMSmart_SM00369,HMMPfam_PP2C,HMMSmart_SM00364,superfamily_L domain-like	-	no_errors	331	24	6.76	75	45	36.59	16	20	55.56
MUC16	0	genome.wustl.edu	36	19	8945715	8945715	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	19	8945715	8945715	C	T	SNP	MUC16	NM_024690.2	human	genbank	54_36p	-1	validated	missense	c.7100	p.S2367N	0.000	NULL	HMMPfam_SEA,HMMSmart_SM00200,PatternScan_ATPASE_ALPHA_BETA,superfamily_SEA domain	-	no_errors	530	42	7.34	144	96	40.00	NA	NA	NA
NPM1	0	genome.wustl.edu	36	5	170770151	170770152	+	Frame_Shift_Ins	INS	-	-	TGTA			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	-	-	-	TGTA	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	5	170770151	170770152	-	TGTA	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.862_863	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
VWCE	0	genome.wustl.edu	36	11	60802458	60802458	+	Frame_Shift_Del	DEL	G	G	-			TCGA-AB-2924-03A-01W-0745-08	TCGA-AB-2924-11A-01W-0745-08	G	G	G	-	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	16d51cf8-f922-4c2b-ac3f-744064cb04f4	207d9855-296b-4155-9e3a-6011d6102505	11	60802458	60802458	G	-	DEL	VWCE	NM_152718.2	human	genbank	54_36p	-1	validated	frame_shift_del	c.1391	p.V465fs	1.000	HMMPfam_VWC,HMMSmart_SM00214,HMMSmart_SM00215	PatternScan_ASX_HYDROXYL,HMMPfam_VWC,HMMSmart_SM00214,PatternScan_VWFC_1,HMMSmart_SM00179,HMMSmart_SM00181,HMMSmart_SM00215,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,HMMPfam_EGF_2,PatternScan_EGF_CA,PatternScan_C_TYPE_LECTIN_1,superfamily_EGF/Laminin	-	no_errors	251	0	0.00	75	0	0.00	1	0	0.00