Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	184	12	6.00	15	21	58.33	NA	NA	NA
NBEAL1	0	genome.wustl.edu	36	2	203753406	203753406	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	2	203753406	203753406	T	C	SNP	NBEAL1	NM_001099273.1	human	genbank	54_36p	+1	validated	missense	c.2564	p.M855T	1.000	HMMPfam_Beach,superfamily_BEACH domain	HMMPfam_Beach,superfamily_BEACH domain,HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40,superfamily_PH domain-like	-	no_errors	81	4	4.71	46	26	36.11	NA	NA	NA
IDH1	0	genome.wustl.edu	36	2	208821357	208821357	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	2	208821357	208821357	C	T	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.395	p.R132H	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	70	2	2.70	33	14	29.17	NA	NA	NA
KIT	0	genome.wustl.edu	36	4	55294078	55294078	+	Missense_Mutation	SNP	A	A	T	rs121913507		TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	4	55294078	55294078	A	T	SNP	KIT	NM_000222.2	human	genbank	54_36p	+1	reviewed	missense	c.2447	p.D816V	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,HMMSmart_IGc2,HMMSmart_IG,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	74	4	5.00	23	29	55.77	NA	NA	NA
ADAMTS12	0	genome.wustl.edu	36	5	33673537	33673537	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	5	33673537	33673537	C	T	SNP	ADAMTS12	NM_030955.2	human	genbank	54_36p	-1	reviewed	missense	c.1790	p.R597H	0.082	HMMSmart_SM00209	"HMMPfam_TSP_1,HMMSmart_SM00209,superfamily_TSP-1 type 1 repeat,HMMPfam_Reprolysin,HMMPfam_Pep_M12B_propep,HMMPfam_ADAM_spacer1,superfamily_Metalloproteases (""zincins"") catalytic domain"	-	no_errors	122	10	7.52	98	43	30.50	NA	NA	NA
SPACA1	0	genome.wustl.edu	36	6	88820400	88820400	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	6	88820400	88820400	G	A	SNP	SPACA1	NM_030960.2	human	genbank	54_36p	+1	reviewed	missense	c.226	p.V76I	0.426	NULL	NULL	-	no_errors	94	4	4.08	57	20	25.97	NA	NA	NA
C10orf120	0	genome.wustl.edu	36	10	124447259	124447259	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	10	124447259	124447259	C	G	SNP	C10orf120	NM_001010912.1	human	genbank	54_36p	-1	predicted	missense	c.988	p.A330P	0.000	NULL	NULL	-	no_errors	171	10	5.41	68	41	37.61	NA	NA	NA
DTX4	0	genome.wustl.edu	36	11	58705933	58705933	+	Silent	SNP	G	G	A			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	11	58705933	58705933	G	A	SNP	DTX4	NM_015177.1	human	genbank	54_36p	+1	validated	silent	c.357	p.K119	1.000	HMMPfam_WWE,HMMSmart_SM00678	HMMSmart_SM00184,HMMPfam_WWE,HMMSmart_SM00678,HMMPfam_zf-C3HC4,superfamily_RING/U-box	-	no_errors	178	11	5.79	25	20	44.44	NA	NA	NA
CARD18	0	genome.wustl.edu	36	11	104515003	104515003	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	11	104515003	104515003	C	T	SNP	CARD18	NM_021571.2	human	genbank	54_36p	-1	validated	missense	c.20	p.R7H	0.000	HMMPfam_CARD,HMMSmart_CARD,superfamily_DEATH_like	HMMPfam_CARD,HMMSmart_CARD,superfamily_DEATH_like	-	no_errors	170	22	11.34	76	65	45.77	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27490640	27490640	+	Missense_Mutation	SNP	A	A	T	rs121913487		TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	13	27490640	27490640	A	T	SNP	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	missense	c.2505	p.D835E	0.991	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	119	6	4.55	40	10	20.00	NA	NA	NA
SDR42E1	0	genome.wustl.edu	36	16	80590579	80590579	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	16	80590579	80590579	C	T	SNP	SDR42E1	NM_145168.2	human	genbank	54_36p	-1	validated	missense	c.820	p.G274S	1.000	HMMPfam_3Beta_HSD,superfamily_NAD(P)-bd	HMMPfam_3Beta_HSD,superfamily_NAD(P)-bd	-	no_errors	101	9	8.04	32	23	41.82	NA	NA	NA
NPM1	0	genome.wustl.edu	36	5	170770152	170770153	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	5	170770152	170770153	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.863_864	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
POLA2	0	genome.wustl.edu	36	11	64786408	64786412	+	Frame_Shift_Del	DEL	AATTG	AATTG	-			TCGA-AB-2945-03A-01W-0733-08	TCGA-AB-2945-11A-01W-0732-08	AATTG	AATTG	AATTG	-	AATTG	AATTG	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	45e961ad-9a6a-49ed-9e69-d80020ab93f3	c19658a4-1073-42aa-aa50-ab3140760804	11	64786408	64786412	AATTG	-	DEL	POLA2	NM_002689.2	human	genbank	54_36p	+1	provisional	frame_shift_del	c.69_73	p.I24fs	0.000:0.000:0.000:0.004:0.836	HMMPfam_Pol_alpha_B_N	HMMPfam_DNA_pol_E_B,HMMPfam_Pol_alpha_B_N	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA