Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	112	8	6.67	26	21	44.68	45	60	57.14
LOC129293	0	genome.wustl.edu	36	2	84951165	84951165	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	2	84951165	84951165	G	T	SNP	LOC129293	NM_001080824.1	human	genbank	54_36p	-1	predicted	missense	c.364	p.R122S	0.997	NULL	NULL	-	no_errors	65	2	2.99	23	22	48.89	NA	NA	NA
IDH1	0	genome.wustl.edu	36	2	208821357	208821357	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	2	208821357	208821357	C	T	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.395	p.R132H	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	86	6	6.52	32	25	43.86	37	23	38.33
SLC4A3	0	genome.wustl.edu	36	2	220213566	220213566	+	Splice_Site	SNP	G	G	A			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	2	220213566	220213566	G	A	SNP	SLC4A3	NM_201574.3	human	genbank	54_36p	+1	validated	splice_site	c.3528+1	e20+1	1.000	-	-	-	no_errors	110	1	0.89	52	9	14.75	0	0	0.00
SPHKAP	0	genome.wustl.edu	36	2	228705007	228705007	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	2	228705007	228705007	G	A	SNP	SPHKAP	NM_030623.1	human	genbank	54_36p	-1	validated	missense	c.71	p.P24L	0.000	NULL	HMMPfam_AKAP_110	-	no_errors	85	1	1.16	54	32	37.21	NA	NA	NA
LRCH3	0	genome.wustl.edu	36	3	199040920	199040920	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	3	199040920	199040920	G	A	SNP	LRCH3	NM_032773.2	human	genbank	54_36p	+1	provisional	missense	c.866	p.R289K	1.000	superfamily_SSF52058	HMMPfam_LRR_1,superfamily_Calponin-homology,superfamily_SSF52058	-	no_errors	109	2	1.79	65	58	46.77	14	18	56.25
ST8SIA4	0	genome.wustl.edu	36	5	100250084	100250084	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	5	100250084	100250084	T	C	SNP	ST8SIA4	NM_005668.4	human	genbank	54_36p	-1	reviewed	missense	c.365	p.H122R	0.997	HMMPfam_Glyco_transf_29	HMMPfam_Glyco_transf_29	-	no_errors	56	2	3.33	33	27	45.00	30	25	45.45
NMUR2	0	genome.wustl.edu	36	5	151764747	151764747	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	5	151764747	151764747	G	A	SNP	NMUR2	NM_020167.4	human	genbank	54_36p	-1	reviewed	missense	c.121	p.R41C	0.866	superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	88	3	3.26	57	24	29.27	NA	NA	NA
VLDLR	0	genome.wustl.edu	36	9	2642945	2642945	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	9	2642945	2642945	C	G	SNP	VLDLR	NM_003383.1	human	genbank	54_36p	+1	validated	missense	c.2582	p.P861R	1.000	NULL	HMMPfam_Ldl_recept_b,HMMSmart_SM00135,PatternScan_ASX_HYDROXYL,HMMSmart_SM00179,HMMPfam_Ldl_recept_a,HMMSmart_SM00192,PatternScan_LDLRA_1,superfamily_LDL receptor-like module,HMMPfam_EGF,HMMSmart_SM00181,PatternScan_EGF_2,HMMPfam_EGF_CA,PatternScan_EGF_CA,superfamily_EGF/Laminin,superfamily_YWTD domain	-	no_errors	76	1	1.30	53	53	50.00	1	0	0.00
CHD4	0	genome.wustl.edu	36	12	6571844	6571844	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	12	6571844	6571844	C	T	SNP	CHD4	NM_001273.2	human	genbank	54_36p	-1	reviewed	missense	c.2924	p.R975H	1.000	HMMPfam_SNF2_N	HMMPfam_SNF2_N,HMMPfam_Chromo,HMMSmart_SM00298,PatternScan_CHROMO_1,HMMPfam_Helicase_C,HMMSmart_SM00490,HMMSmart_SM00249,PatternScan_DEAH_ATP_HELICASE,HMMPfam_DUF1086,HMMPfam_DUF1087,superfamily_FYVE/PHD zinc finger,HMMPfam_CHDCT2,HMMPfam_CHDNT,HMMSmart_SM00487,superfamily_Chromo domain-like,PatternScan_ZF_PHD_1,HMMPfam_PHD,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	198	8	3.86	146	54	26.87	175	67	27.69
ORAI1	0	genome.wustl.edu	36	12	120563336	120563336	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	12	120563336	120563336	A	G	SNP	ORAI1	NM_032790.3	human	genbank	54_36p	+1	reviewed	missense	c.316	p.M106V	0.997	HMMPfam_DUF1650	HMMPfam_DUF1650	-	no_errors	129	3	2.24	52	22	29.73	107	64	37.43
NRXN3	0	genome.wustl.edu	36	14	78245493	78245493	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	14	78245493	78245493	A	G	SNP	NRXN3	NM_004796.1	human	genbank	54_36p	+1	reviewed	missense	c.283	p.M95V	0.998	HMMSmart_LamG,superfamily_ConA_like_lec_gl	PatternScan_ASX_HYDROXYL,HMMSmart_LamG,HMMSmart_4.1m,HMMPfam_EGF,HMMSmart_EGF,superfamily_ConA_like_lec_gl,HMMPfam_Laminin_G_2	-	no_errors	115	2	1.71	50	26	33.77	NA	NA	NA
LOC646090	0	genome.wustl.edu	36	15	18727164	18727164	+	RNA	SNP	G	G	C			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	15	18727164	18727164	G	C	SNP	LOC646090	XR_017120.2	human	genbank	54_36p	-1	model	rna	NULL	NULL	0.961	-	-	-	pseudogene	276	7	2.44	53	26	32.91	NA	NA	NA
CCL11	0	genome.wustl.edu	36	17	29638754	29638754	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	17	29638754	29638754	C	T	SNP	CCL11	NM_002986.2	human	genbank	54_36p	+1	reviewed	missense	c.226	p.P76S	0.992	HMMPfam_IL8,HMMSmart_SM00199,superfamily_Interleukin 8-like chemokines	PatternScan_SMALL_CYTOKINES_CC,HMMPfam_IL8,HMMSmart_SM00199,superfamily_Interleukin 8-like chemokines	-	no_errors	53	1	1.82	49	36	42.35	NA	NA	NA
SUZ12	0	genome.wustl.edu	36	17	27334134	27334135	+	Frame_Shift_Del	DEL	CT	CT	-			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	CT	CT	CT	-	CT	CT	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	17	27334134	27334135	CT	-	DEL	SUZ12	NM_015355.2	human	genbank	54_36p	+1	reviewed	frame_shift_del	c.921_922	p.L308fs	0.998:0.998	NULL	PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,HMMPfam_VEFS-Box	-	no_errors	0	2	4.08	0	11	40.74	0	0	0.00
NCOA3	0	genome.wustl.edu	36	20	45697745	45697745	+	Frame_Shift_Del	DEL	A	A	-			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	A	A	A	-	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	20	45697745	45697745	A	-	DEL	NCOA3	NM_181659.2	human	genbank	54_36p	+1	reviewed	frame_shift_del	c.1385	p.N462fs	0.984	NULL	HMMSmart_SM00091,HMMPfam_HLH,HMMSmart_SM00353,superfamily_Nuclear receptor coactivator interlocking domain,HMMPfam_DUF1518,superfamily_HLH helix-loop-helix DNA-binding domain,HMMPfam_PAS,HMMPfam_Nuc_rec_co-act,HMMPfam_SRC-1,superfamily_PYP-like sensor domain (PAS domain)	-	no_errors	141	0	0.00	92	0	0.00	28	0	0.00
RUNX1	0	genome.wustl.edu	36	21	35093494	35093495	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-AB-2949-03A-01W-0733-08	TCGA-AB-2949-11A-01W-0732-08	AG	AG	AG	-	AG	AG	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	93918a62-e102-4cf1-a403-81845f830c3e	ed5227d3-b5bf-4356-a6c2-3af0065be735	21	35093494	35093495	AG	-	DEL	RUNX1	NM_001754.2	human	genbank	54_36p	-1	reviewed	frame_shift_del	c.941_940	p.S314fs	1.000:1.000	NULL	superfamily_p53-like transcription factors,HMMPfam_Runt,HMMPfam_RunxI	-	no_errors	0	0	0.00	0	0	0.00	0	0	0.00