Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
NRAS	0	genome.wustl.edu	36	1	115058051	115058051	+	Missense_Mutation	SNP	T	T	A	rs121913255		TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	1	115058051	115058051	T	A	SNP	NRAS	NM_002524.3	human	genbank	54_36p	-1	reviewed	missense	c.183	p.Q61H	1.000	HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	474	3	0.63	336	99	22.60	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25316775	25316775	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	2	25316775	25316775	G	A	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2222	p.A741V	1.000	HMMPfam_DNA_methylase,superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	212	1	0.47	143	132	47.83	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25322533	25322533	+	Nonsense_Mutation	SNP	C	C	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	2	25322533	25322533	C	A	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	nonsense	c.1429	p.E477*	1.000	NULL	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	179	1	0.56	156	104	40.00	NA	NA	NA
DDX60	0	genome.wustl.edu	36	4	169378394	169378394	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	4	169378394	169378394	T	C	SNP	DDX60	NM_017631.5	human	genbank	54_36p	-1	validated	missense	c.5026	p.I1676V	0.362	NULL	HMMPfam_Helicase_C,HMMSmart_SM00490,HMMPfam_DEAD,HMMSmart_SM00487,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	466	8	1.68	113	85	42.93	NA	NA	NA
NIPBL	0	genome.wustl.edu	36	5	37099862	37099862	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	5	37099862	37099862	A	G	SNP	NIPBL	NM_015384.4	human	genbank	54_36p	+1	reviewed	missense	c.8074	p.I2692V	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	312	7	2.19	197	149	43.06	NA	NA	NA
EXOC2	0	genome.wustl.edu	36	6	537581	537581	+	Silent	SNP	C	C	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	6	537581	537581	C	G	SNP	EXOC2	NM_018303.4	human	genbank	54_36p	-1	reviewed	silent	c.1080	p.L360	1.000	NULL	HMMPfam_TIG,superfamily_Ig_E-set	-	no_errors	348	2	0.57	180	127	41.37	NA	NA	NA
FBXL18	0	genome.wustl.edu	36	7	5506935	5506935	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	7	5506935	5506935	G	A	SNP	FBXL18	ENST00000297035	human	ensembl	54_36p	-1	known	missense	c.166	p.R56C	0.174	NULL	NULL	-	no_errors	130	2	1.52	100	73	42.20	NA	NA	NA
LOC100133915	0	genome.wustl.edu	36	8	1591559	1591559	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	8	1591559	1591559	C	G	SNP	LOC100133915	XM_001715423.1	human	genbank	54_36p	-1	model	missense	c.1367	p.C456S	0.000	NULL	NULL	-	no_start_codon:pseudogene:no_stop_codon	309	4	1.28	196	173	46.51	NA	NA	NA
COMMD5	0	genome.wustl.edu	36	8	146047513	146047513	+	Silent	SNP	C	C	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	8	146047513	146047513	C	G	SNP	COMMD5	NM_001081003.1	human	genbank	54_36p	-1	validated	silent	c.15	p.G5	0.745	NULL	HMMPfam_HCaRG	-	no_errors	169	6	3.43	103	72	41.14	NA	NA	NA
PTCH1	0	genome.wustl.edu	36	9	97269319	97269319	+	Silent	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	9	97269319	97269319	G	A	SNP	PTCH1	NM_000264.3	human	genbank	54_36p	-1	reviewed	silent	c.2460	p.Y820	0.971	HMMPfam_Patched	HMMPfam_Patched,superfamily_SSF82866	-	no_errors	445	5	1.11	171	83	32.68	NA	NA	NA
LOC387820	0	genome.wustl.edu	36	11	127316318	127316318	+	RNA	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	11	127316318	127316318	G	A	SNP	LOC387820	XR_017453.2	human	genbank	54_36p	-1	model	rna	NULL	NULL	0.997	-	-	-	pseudogene	286	4	1.38	140	50	26.32	NA	NA	NA
PLCZ1	0	genome.wustl.edu	36	12	18757102	18757102	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	12	18757102	18757102	G	A	SNP	PLCZ1	NM_033123.2	human	genbank	54_36p	-1	provisional	missense	c.655	p.L219F	0.998	HMMPfam_PI-PLC-X,HMMSmart_SM00148,superfamily_PLC-like phosphodiesterases	HMMPfam_C2,HMMSmart_SM00239,HMMPfam_PI-PLC-X,HMMSmart_SM00148,HMMPfam_PI-PLC-Y,HMMSmart_SM00149,superfamily_C2 domain (Calcium/lipid-binding domain CaLB),HMMPfam_efhand_like,superfamily_PLC-like phosphodiesterases,superfamily_EF-hand	-	no_errors	744	9	1.20	296	256	46.38	NA	NA	NA
EIF4B	0	genome.wustl.edu	36	12	51699990	51699990	+	Silent	SNP	C	C	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	12	51699990	51699990	C	G	SNP	EIF4B	NM_001417.4	human	genbank	54_36p	+1	validated	silent	c.390	p.P130	1.000	HMMPfam_RRM_1,HMMSmart_RRM,superfamily_SSF54928	HMMPfam_RRM_1,HMMSmart_RRM,superfamily_SSF54928	-	no_errors	337	6	1.75	127	86	40.38	NA	NA	NA
KSR2	0	genome.wustl.edu	36	12	116406649	116406649	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	12	116406649	116406649	G	A	SNP	KSR2	NM_173598.4	human	genbank	54_36p	-1	validated	missense	c.2042	p.T681M	1.000	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase	HMMSmart_SM00219,HMMPfam_C1_1,HMMSmart_SM00109,PatternScan_ZF_DAG_PE_1,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase,superfamily_Cysteine-rich domain	-	no_errors	462	10	2.12	240	190	44.08	NA	NA	NA
MTUS2	0	genome.wustl.edu	36	13	28753919	28753919	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	13	28753919	28753919	G	A	SNP	KIAA0774	NM_001033602.2	human	genbank	54_36p	+1	validated	missense	c.2753	p.R918Q	0.496	NULL	NULL	-	no_errors	259	2	0.77	247	185	42.82	NA	NA	NA
BPTF	0	genome.wustl.edu	36	17	63338445	63338445	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	17	63338445	63338445	T	G	SNP	BPTF	NM_182641.6	human	genbank	54_36p	+1	reviewed	missense	c.3983	p.V1328G	0.020	NULL	HMMPfam_Bromodomain,HMMSmart_BROMO,superfamily_Bromodomain,HMMSmart_PHD,HMMPfam_DDT,superfamily_FYVE_PHD_ZnF,HMMPfam_FYDLN_acid,PatternScan_EGF_2,PatternScan_BROMODOMAIN_1,HMMSmart_DDT,PatternScan_ZF_PHD_1,HMMPfam_PHD	-	no_errors	407	5	1.21	236	145	38.06	NA	NA	NA
PRODH2	0	genome.wustl.edu	36	19	40995491	40995491	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	19	40995491	40995491	C	T	SNP	PRODH2	NM_021232.1	human	genbank	54_36p	-1	reviewed	nonsense	c.285	p.W95*	0.998	NULL	HMMPfam_Pro_dh,superfamily_SSF51730	-	no_errors	537	8	1.47	181	148	44.98	NA	NA	NA
U2AF1	0	genome.wustl.edu	36	21	43397525	43397525	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	21	43397525	43397525	G	A	SNP	U2AF1	NM_001025203.1	human	genbank	54_36p	-1	reviewed	missense	c.101	p.S34F	1.000	HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1	HMMPfam_RRM_1,HMMSmart_RRM,HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1,superfamily_SSF54928	-	no_errors	252	10	3.82	77	62	44.60	NA	NA	NA
BCOR	0	genome.wustl.edu	36	X	39817028	39817029	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	-	-	-	G	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	X	39817028	39817029	-	G	INS	BCOR	NM_017745.1	human	genbank	54_36p	-1	reviewed	frame_shift_ins	c.2515_2514	p.K838fs	0.579:0.203	NULL	HMMPfam_Ank,HMMSmart_ANK,superfamily_ANK	-	no_errors	89	2	2.20	42	69	62.16	NA	NA	NA
CCNG2	0	genome.wustl.edu	36	4	78306068	78306068	+	Frame_Shift_Del	DEL	C	C	-			TCGA-AB-2968-03A-01D-0739-09	TCGA-AB-2968-11A-01D-0739-09	C	C	C	-	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	85d9ba67-6bb0-440d-8d9f-1c9582697ba6	2f3495f2-e136-437c-8c9a-a2e01db92a3e	4	78306068	78306068	C	-	DEL	CCNG2	NM_004354.2	human	genbank	54_36p	+1	reviewed	frame_shift_del	c.1002	p.F334fs	0.971	NULL	HMMSmart_SM00385,HMMPfam_Cyclin_N,superfamily_Cyclin-like	-	no_errors	551	10	1.78	254	184	40.44	NA	NA	NA