Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	965	71	6.83	592	301	33.63	16	7	30.43
PDGFRA	0	genome.wustl.edu	36	4	54851324	54851324	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	4	54851324	54851324	G	C	SNP	PDGFRA	NM_006206.4	human	genbank	54_36p	+1	reviewed	missense	c.2968	p.G990R	0.999	NULL	HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,PatternScan_RECEPTOR_TYR_KIN_III,HMMSmart_SM00220,HMMSmart_SM00408,HMMSmart_SM00409,PatternScan_PROTEIN_KINASE_TYR,superfamily_Protein kinase-like (PK-like),HMMPfam_I-set,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_Immunoglobulin	-	no_errors	1526	93	5.74	924	426	31.44	NA	NA	NA
ENC1	0	genome.wustl.edu	36	5	73966654	73966654	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	5	73966654	73966654	C	G	SNP	ENC1	NM_003633.2	human	genbank	54_36p	-1	validated	missense	c.1413	p.R471S	1.000	HMMPfam_Kelch_1,HMMSmart_SM00612,superfamily_Galactose oxidase central domain	HMMSmart_SM00225,HMMPfam_Kelch_1,HMMSmart_SM00612,superfamily_Galactose oxidase central domain,superfamily_POZ domain,HMMPfam_BACK,HMMPfam_BTB	-	no_errors	945	65	6.43	506	247	32.76	4	5	55.56
PTPRE	0	genome.wustl.edu	36	10	129744414	129744414	+	Missense_Mutation	SNP	T	T	A			TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	10	129744414	129744414	T	A	SNP	PTPRE	NM_006504.4	human	genbank	54_36p	+1	reviewed	missense	c.458	p.L153Q	0.997	HMMSmart_SM00194,superfamily_(Phosphotyrosine protein) phosphatases II	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	1466	107	6.80	1104	553	33.29	105	114	52.05
KRAS	0	genome.wustl.edu	36	12	25289548	25289548	+	Missense_Mutation	SNP	C	C	T	rs112445441		TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	12	25289548	25289548	C	T	SNP	KRAS	NM_033360.3	human	genbank	54_36p	-1	reviewed	missense	c.38	p.G13D	1.000	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	962	54	5.29	1012	459	31.14	9	10	52.63
KRTAP10-8	0	genome.wustl.edu	36	21	44856866	44856866	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	21	44856866	44856866	G	A	SNP	KRTAP10-8	NM_198695.1	human	genbank	54_36p	+1	provisional	missense	c.421	p.A141T	0.041	NULL	HMMPfam_Keratin_B2	-	no_errors	1919	119	5.82	1206	578	31.97	NA	NA	NA
NPM1	0	genome.wustl.edu	36	5	170770152	170770153	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2987-03A-01D-0739-09	TCGA-AB-2987-11A-01D-0739-09	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	372359dc-f250-4f75-a817-01c92fe03688	e0cc389e-0e7c-4e40-885e-4b3427f1cc36	5	170770152	170770153	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.863_864	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA