Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU LOC100130211 0 genome.wustl.edu 36 X 85302265 85302265 + Missense_Mutation SNP C C T TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 X 85302265 85302265 C T SNP LOC100130211 XM_001717632.1 human genbank 54_36p -1 model missense c.736 p.G246S 1.000 HMMPfam_GTP_EFTU_D3,superfamily_EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain HMMPfam_GTP_EFTU,HMMPfam_GTP_EFTU_D3,HMMPfam_GTP_EFTU_D2,superfamily_Translation proteins,superfamily_EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain,superfamily_P-loop containing nucleoside triphosphate hydrolases - pseudogene 306 10 3.16 105 709 87.10 NA NA NA RAB25 0 genome.wustl.edu 36 1 154302405 154302405 + Missense_Mutation SNP C C A TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 1 154302405 154302405 C A SNP RAB25 NM_020387.2 human genbank 54_36p +1 provisional missense c.123 p.S41R 0.993 HMMSmart_RAB,HMMPfam_Ras,superfamily_SSF52540 HMMSmart_RAB,HMMPfam_Ras,superfamily_SSF52540 - no_errors 718 13 1.78 245 179 42.22 NA NA NA MAGI1 0 genome.wustl.edu 36 3 65391533 65391533 + Missense_Mutation SNP C C T TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 3 65391533 65391533 C T SNP MAGI1 NM_001033057.1 human genbank 54_36p -1 reviewed missense c.1427 p.R476Q 1.000 HMMPfam_PDZ,superfamily_PDZ domain-like HMMPfam_WW,HMMSmart_SM00456,PatternScan_WW_DOMAIN_1,superfamily_WW domain,HMMPfam_PDZ,HMMSmart_SM00228,superfamily_PDZ domain-like,HMMPfam_Guanylate_kin,HMMSmart_SM00072,PatternScan_GUANYLATE_KINASE_1,superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors 743 12 1.59 1076 843 43.88 NA NA NA PDK4 0 genome.wustl.edu 36 7 95055034 95055034 + Missense_Mutation SNP G G A TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 7 95055034 95055034 G A SNP PDK4 NM_002612.3 human genbank 54_36p -1 reviewed missense c.811 p.P271S 0.859 HMMPfam_HATPase_c,HMMSmart_SM00387,superfamily_ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HMMPfam_HATPase_c,HMMSmart_SM00387,superfamily_ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase,HMMPfam_BCDHK_Adom3,superfamily_alpha-ketoacid dehydrogenase kinase N-terminal domain - no_errors 384 15 3.76 571 425 42.63 NA NA NA CBL 0 genome.wustl.edu 36 11 118654090 118654090 + Missense_Mutation SNP A A G TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 A A A G A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 11 118654090 118654090 A G SNP CBL NM_005188.2 human genbank 54_36p +1 reviewed missense c.1100 p.Q367R 1.000 superfamily_SSF57850 HMMPfam_UBA,HMMSmart_RING,HMMPfam_Cbl_N,superfamily_Adaptor_Cbl_N,HMMPfam_Cbl_N2,HMMPfam_Cbl_N3,HMMSmart_UBA,PatternScan_ZF_RING_1,HMMPfam_zf-C3HC4,superfamily_SSF47473,superfamily_SSF55550,superfamily_SSF57850 - no_errors 138 2 1.43 86 208 70.75 NA NA NA GABRG3 0 genome.wustl.edu 36 15 25446355 25446355 + Silent SNP G G A TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 15 25446355 25446355 G A SNP GABRG3 ENST00000333743 human ensembl 54_36p +1 known silent c.1047 p.T349 0.011 HMMPfam_Neur_chan_memb,superfamily_Neu_channel_TM HMMPfam_Neur_chan_memb,superfamily_Neu_channel_TM,HMMPfam_Neur_chan_LBD,superfamily_Neur_chan_LBD,PatternScan_NEUROTR_ION_CHANNEL - no_errors 892 29 3.14 989 833 45.69 NA NA NA DLX3 0 genome.wustl.edu 36 17 45423898 45423898 + Missense_Mutation SNP G G T TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 17 45423898 45423898 G T SNP DLX3 NM_005220.2 human genbank 54_36p -1 reviewed missense c.846 p.N282K 1.000 NULL HMMPfam_Homeobox,HMMSmart_SM00389,superfamily_Homeodomain-like,PatternScan_HOMEOBOX_1 - no_errors 585 12 2.01 206 146 41.36 NA NA NA SUPT5H 0 genome.wustl.edu 36 19 44641493 44641493 + Missense_Mutation SNP G G C TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 G G G C G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 19 44641493 44641493 G C SNP SUPT5H NM_003169.2 human genbank 54_36p +1 validated missense c.398 p.R133P 1.000 NULL HMMPfam_Supt5,HMMPfam_KOW,HMMSmart_SM00739,HMMSmart_SM00738,superfamily_Translation proteins SH3-like domain - no_errors 1241 45 3.50 783 521 39.83 NA NA NA HNRNPUL1 0 genome.wustl.edu 36 19 46478923 46478923 + Missense_Mutation SNP C C T TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 19 46478923 46478923 C T SNP HNRNPUL1 NM_007040.3 human genbank 54_36p +1 reviewed missense c.902 p.S301F 1.000 HMMPfam_SPRY,HMMSmart_SM00449 HMMPfam_SAP,HMMSmart_SM00513,HMMPfam_SPRY,HMMSmart_SM00449,superfamily_P-loop containing nucleoside triphosphate hydrolases,superfamily_SAP domain - no_errors 516 6 1.15 537 430 44.42 NA NA NA TRPC4AP 0 genome.wustl.edu 36 20 33144232 33144232 + Missense_Mutation SNP G G A TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 20 33144232 33144232 G A SNP TRPC4AP NM_015638.2 human genbank 54_36p -1 validated missense c.14 p.P5L 0.997 NULL NULL - no_errors 129 1 0.76 77 63 43.75 NA NA NA GPBP1 0 genome.wustl.edu 36 5 56578691 56578692 + Frame_Shift_Ins INS - - A TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 - - - A - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 5 56578691 56578692 - A INS GPBP1 NM_022913.1 human genbank 54_36p +1 validated frame_shift_ins c.696_697 p.V233fs 1.000:1.000 NULL NULL - no_errors 168 0 0.00 239 124 34.16 NA NA NA NPM1 0 genome.wustl.edu 36 5 170770152 170770153 + Frame_Shift_Ins INS - - TCAG TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 - - - TCAG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 5 170770152 170770153 - TCAG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.863_864 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA WT1 0 genome.wustl.edu 36 11 32374422 32374423 + Frame_Shift_Del DEL AT AT - TCGA-AB-2989-03A-01D-0739-09 TCGA-AB-2989-11A-01D-0739-09 AT AT AT - AT AT Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq b385b03f-4ee1-4be9-9291-9b5fdfd66384 baa70711-9504-4ebc-8e86-a870629d4161 11 32374422 32374423 AT - DEL WT1 NM_024426.3 human genbank 54_36p -1 reviewed frame_shift_del c.1206_1205 p.Y402fs 1.000:1.000 HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers HMMPfam_WT1,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers - no_errors 0 6 1.60 0 170 35.20 NA NA NA