Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
TTN	0	genome.wustl.edu	36	2	179184790	179184790	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	2	179184790	179184790	C	T	SNP	TTN	ENST00000375038	human	ensembl	54_36p	-1	known	missense	c.38437	p.E12813K	1.000	HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,superfamily_Concanavalin A-like lectins/glucanases,superfamily_WD40 repeat-like,superfamily_vWA-like,superfamily_Positive stranded ssRNA viruses	HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_IG_MHC,HMMSmart_SM00406,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,HMMPfam_PPAK,PatternScan_PROTEIN_KINASE_TYR,superfamily_Fibronectin type III,superfamily_Concanavalin A-like lectins/glucanases,superfamily_Protein kinase-like (PK-like),superfamily_WD40 repeat-like,HMMPfam_I-set,HMMPfam_ig,HMMPfam_Titin_Z,HMMPfam_Pkinase,PatternScan_FGGY_KINASES_1,PatternScan_PEROXIDASE_1,superfamily_Immunoglobulin,superfamily_vWA-like,superfamily_Positive stranded ssRNA viruses	-	no_errors	10721	2174	15.75	8955	7039	43.5733333333333	49	52	51.49
LOC339970	0	genome.wustl.edu	36	4	68587383	68587383	+	RNA	SNP	G	G	A			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	4	68587383	68587383	G	A	SNP	LOC339970	XR_038239.1	human	genbank	54_36p	+1	model	rna	NULL	NULL	0.001	-	-	-	pseudogene	11376	1773	13.1466666666667	9969	9083	46.5666666666667	0	1	100.00
CDHR2	0	genome.wustl.edu	36	5	175948939	175948939	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	5	175948939	175948939	C	T	SNP	PCDH24	NM_017675.3	human	genbank	54_36p	+1	reviewed	missense	c.3011	p.P1004L	0.982	HMMPfam_Cadherin,HMMSmart_CA,superfamily_Cadherin	HMMPfam_Cadherin,HMMSmart_CA,PatternScan_CADHERIN_1,superfamily_Cadherin	-	no_errors	8521	794	8.65666666666667	5120	5094	47.8133333333333	NA	NA	NA
CALHM3	0	genome.wustl.edu	36	10	105228735	105228735	+	Silent	SNP	C	C	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	10	105228735	105228735	C	T	SNP	CALHM3	ENST00000369783	human	ensembl	54_36p	-1	known	silent	c.45	p.S15	0.104	NULL	NULL	-	no_errors	11285	3078	20.5166666666667	9204	7466	44.19	NA	NA	NA
SMC3	0	genome.wustl.edu	36	10	112346166	112346166	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	10	112346166	112346166	G	T	SNP	SMC3	NM_005445.3	human	genbank	54_36p	+1	reviewed	missense	c.1984	p.G662C	1.000	HMMPfam_SMC_N,superfamily_Smc hinge domain,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_SMC_N,HMMPfam_SMC_hinge,superfamily_Smc hinge domain,PatternScan_ABC_TRANSPORTER_1,superfamily_P-loop containing nucleoside triphosphate hydrolases,superfamily_BAG domain	-	no_errors	8761	2734	21.7966666666667	9082	7834	50.2833333333333	38	44	53.66
GPR123	0	genome.wustl.edu	36	10	134734535	134734535	+	Missense_Mutation	SNP	C	C	T	rs181856403		TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	10	134734535	134734535	C	T	SNP	GPR123	ENST00000368577	human	ensembl	54_36p	+1	known	missense	c.113	p.T38I	0.000	NULL	HMMPfam_7tm_2,PatternScan_G_PROTEIN_RECEP_F2_2	-	no_errors	8148	2276	20.1333333333333	6337	7481	49.96	NA	NA	NA
RPLP0P2	0	genome.wustl.edu	36	11	61152920	61152920	+	RNA	SNP	C	C	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	11	61152920	61152920	C	T	SNP	RPLP0P2	NR_002775.2	human	genbank	54_36p	+1	inferred	rna	NULL	NULL	0.000	-	-	-	pseudogene	15911	1847	11.01	10880	7475	39.0366666666667	NA	NA	NA
SLC15A1	0	genome.wustl.edu	36	13	98176393	98176393	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	13	98176393	98176393	C	T	SNP	SLC15A1	NM_005073.3	human	genbank	54_36p	-1	validated	nonsense	c.230	p.W77*	1.000	superfamily_MFS general substrate transporter,PatternScan_PTR2_1	HMMPfam_PTR2,superfamily_MFS general substrate transporter,PatternScan_PTR2_1,PatternScan_PTR2_2	-	no_errors	9390	1998	15.6766666666667	8439	9910	51.5	NA	NA	NA
GPR183	0	genome.wustl.edu	36	13	98745388	98745388	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	13	98745388	98745388	G	A	SNP	GPR183	NM_004951.4	human	genbank	54_36p	-1	reviewed	missense	c.1013	p.A338V	1.000	superfamily_SSF81321	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_SSF81321	-	no_errors	7168	1857	20.4166666666667	4671	3872	47.1566666666667	27	45	62.50
CDH24	0	genome.wustl.edu	36	14	22588266	22588266	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	14	22588266	22588266	G	T	SNP	CDH24	NM_022478.3	human	genbank	54_36p	-1	validated	nonsense	c.1770	p.Y590*	0.998	HMMPfam_Cadherin,superfamily_Cadherin-like	HMMPfam_Cadherin_C,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like	-	no_errors	4577	1166	15.62	4405	5022	46.8733333333333	3	2	40.00
PDXDC1	0	genome.wustl.edu	36	16	15030292	15030292	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	16	15030292	15030292	G	A	SNP	PDXDC1	NM_015027.2	human	genbank	54_36p	+1	validated	missense	c.1261	p.E421K	0.936	superfamily_PLP-dependent transferases	HMMPfam_Pyridoxal_deC,superfamily_PLP-dependent transferases	-	no_errors	8684	778	8.48	12623	4597	28.0866666666667	44	16	26.23
LOC728896	0	genome.wustl.edu	36	17	43068885	43068885	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	17	43068885	43068885	G	T	SNP	LOC728896	XM_001719193.1	human	genbank	54_36p	-1	model	missense	c.138	p.F46L	0.078	NULL	NULL	-	no_errors	10094	1803	15.19	9861	7311	45.1966666666667	2	0	0.00
PTPRT	0	genome.wustl.edu	36	20	40164254	40164254	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	20	40164254	40164254	G	A	SNP	PTPRT	NM_133170.5	human	genbank	54_36p	-1	reviewed	missense	c.3695	p.P1232L	1.000	HMMPfam_Y_phosphatase,HMMSmart_SM00194,superfamily_(Phosphotyrosine protein) phosphatases II	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_MAM,HMMSmart_SM00137,PatternScan_MAM_1,HMMSmart_SM00404,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,PatternScan_TYR_PHOSPHATASE_1,superfamily_Immunoglobulin,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	7222	1981	20.2533333333333	6478	5396	45.2433333333333	NA	NA	NA
DSCAM	0	genome.wustl.edu	36	21	40336315	40336315	+	Silent	SNP	A	A	G			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	21	40336315	40336315	A	G	SNP	DSCAM	NM_001389.3	human	genbank	54_36p	-1	validated	silent	c.5539	p.L1847	1.000	NULL	HMMSmart_SM00406,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,HMMPfam_I-set,HMMPfam_ig,superfamily_Immunoglobulin	-	no_errors	8549	1538	14.9733333333333	7622	7923	50.64	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25317018	25317018	+	Frame_Shift_Del	DEL	A	A	-			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	A	A	A	-	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	2	25317018	25317018	A	-	DEL	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	frame_shift_del	c.2168	p.L723fs	0.999	HMMPfam_DNA_methylase,superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	1146	187	13.80	400	360	45.28	25	0	0.00
NPM1	0	genome.wustl.edu	36	5	170770152	170770153	+	Frame_Shift_Ins	INS	-	-	CATG			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	-	-	-	CATG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	5	170770152	170770153	-	CATG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.863_864	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506273	27506274	+	In_Frame_Ins	INS	-	-	GAAATCAACGTAGAAGTACTCATTATCTGA			TCGA-AB-2993-03A-01D-0739-09	TCGA-AB-2993-11A-01D-0739-09	-	-	-	GAAATCAACGTAGAAGTACTCATTATCTGA	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e956c79-d82b-4d89-9d05-7133e0caf740	c537a524-b89a-4738-8bbe-b00f335d4a75	13	27506273	27506274	-	GAAATCAACGTAGAAGTACTCATTATCTGA	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1783_1782	p.594in_frame_insSDNEYFYVDF	1.000:1.000	superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA