Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
WHAMMP3	0	broad.mit.edu	37	15	23205098	23205098	+	RNA	SNP	G	G	A	rs146035894	by1000genomes	TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr15:23205098G>A	ENST00000400153.2	-	0	756					NR_003521.1																						CTGGAAGAACGTGGTTGCCAC	0.373000													3	33					0	0	1	0	0
BTN2A3P	0	broad.mit.edu	37	6	26422353	26422353	+	RNA	SNP	C	C	T	rs141013110		TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr6:26422353C>T	ENST00000466808.2	+	0	7																		p.P3S(2)									GCTCATGGAACCAGCTGCTGC	0.622000													6	125					0	0	1	0	0
PCSK9	255738	broad.mit.edu	37	1	55523717	55523717	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr1:55523717G>A	ENST00000302118.5	+	8	1479	c.1189G>A	c.(1189-1191)Gcc>Acc	p.A397T	PCSK9_ENST00000490692.1_3'UTR|PCSK9_ENST00000543384.1_Missense_Mutation_p.A197T	NM_174936.3	NP_777596.2	Q8NBP7	PCSK9_HUMAN	proprotein convertase subtilisin/kexin type 9	397	Peptidase S8.				cellular response to insulin stimulus|cellular response to starvation|cholesterol homeostasis|cholesterol metabolic process|kidney development|liver development|low-density lipoprotein particle receptor catabolic process|lysosomal transport|negative regulation of catalytic activity|negative regulation of low-density lipoprotein particle clearance|negative regulation of receptor recycling|neuron differentiation|positive regulation of neuron apoptosis|positive regulation of receptor internalization|protein autoprocessing|regulation of receptor activity	extracellular space|late endosome|lysosome|perinuclear region of cytoplasm	apolipoprotein receptor binding|identical protein binding|low-density lipoprotein particle receptor binding|serine-type endopeptidase activity|very-low-density lipoprotein particle receptor binding			NS(2)|breast(2)|central_nervous_system(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(1)|liver(2)|lung(4)|ovary(3)|prostate(3)|skin(1)|urinary_tract(1)	32						AGGCATTGCAGCCATGATGCT	0.602000													4	104					0	0	1	0	0
GLI2	2736	broad.mit.edu	37	2	121685032	121685032	+	Translation_Start_Site	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr2:121685032G>A	ENST00000314490.11	+	0	274				GLI2_ENST00000361492.4_Missense_Mutation_p.G82S|GLI2_ENST00000452319.1_Missense_Mutation_p.G82S|GLI2_ENST00000435313.2_3'UTR			P10070	GLI2_HUMAN	GLI family zinc finger 2						axon guidance|branching morphogenesis of a tube|cell proliferation|cerebellar cortex morphogenesis|developmental growth|embryonic digestive tract development|epidermal cell differentiation|floor plate formation|heart development|hindgut morphogenesis|kidney development|lung development|negative regulation of transcription from RNA polymerase II promoter|odontogenesis of dentine-containing tooth|osteoblast development|osteoblast differentiation|pituitary gland development|positive regulation of DNA replication|positive regulation of T cell differentiation in thymus|positive regulation of transcription from RNA polymerase II promoter|proximal/distal pattern formation|skeletal system development|smoothened signaling pathway involved in ventral spinal cord interneuron specification|spinal cord ventral commissure morphogenesis	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(1)|breast(3)|central_nervous_system(4)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(7)|lung(24)|ovary(8)|pancreas(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	64	Renal(3;0.0496)	Prostate(154;0.0623)				TTCTGTCCACGGTGTGCACGG	0.622000													35	212					0	0	1	0	0
HSPA13	6782	broad.mit.edu	37	21	15750617	15750617	+	Silent	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr21:15750617T>C	ENST00000285667.3	-	3	550	c.483A>G	c.(481-483)gcA>gcG	p.A161A	HSPA13_ENST00000544452.1_Intron	NM_006948.4	NP_008879.3	P48723	HSP13_HUMAN	heat shock protein 70kDa family, member 13	161						endoplasmic reticulum|microsome	ATP binding			NS(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(5)|skin(1)|upper_aerodigestive_tract(1)	13						TTCCAAGATATGCCTCTGCCA	0.408000													83	113					0	0	1	0	0
C7	730	broad.mit.edu	37	5	40959677	40959677	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr5:40959677C>T	ENST00000313164.9	+	12	1975	c.1616C>T	c.(1615-1617)aCg>aTg	p.T539M		NM_000587.2	NP_000578.2	P10643	CO7_HUMAN	complement component 7	539	TSP type-1 2.				complement activation, alternative pathway|complement activation, classical pathway|cytolysis	extracellular region|membrane attack complex		p.T539M(1)					Ovarian(839;0.0112)				GTTGGAGAAACGACAGAAAGC	0.542000													11	29					0	0	1	0	0
TGOLN2	10618	broad.mit.edu	37	2	85554633	85554633	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr2:85554633C>T	ENST00000377386.3	-	2	684	c.222G>A	c.(220-222)gcG>gcA	p.A74A	TGOLN2_ENST00000409232.3_Silent_p.A74A|TGOLN2_ENST00000409015.1_Silent_p.A74A|TGOLN2_ENST00000398263.2_Silent_p.A74A|TGOLN2_ENST00000282120.2_Intron|TGOLN2_ENST00000444342.2_Silent_p.A74A			O43493	TGON2_HUMAN	trans-golgi network protein 2	74	14 X 14 AA tandem repeats.			A -> P (in Ref. 4; BAD96783).		integral to membrane|nucleus|plasma membrane|trans-Golgi network|transport vesicle	protein binding										CTGGGGTCTGCGCCTCCGCAC	0.607000													7	715					0	0	1	0	0
TRANK1	9881	broad.mit.edu	37	3	36896948	36896948	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr3:36896948G>A	ENST00000429976.2	-	12	4380	c.4133C>T	c.(4132-4134)tCg>tTg	p.S1378L	TRANK1_ENST00000428977.2_Missense_Mutation_p.S828L|TRANK1_ENST00000301807.6_Missense_Mutation_p.S828L			O15050	TRNK1_HUMAN	tetratricopeptide repeat and ankyrin repeat containing 1	1378					DNA repair		ATP binding|ATP-dependent DNA helicase activity|DNA binding			NS(2)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|lung(20)|ovary(1)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	73						CCTGAGCTTCGACAGCCTCCG	0.488000													115	196					0	0	1	0	0
MUC17	140453	broad.mit.edu	37	7	100676201	100676201	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr7:100676201C>T	ENST00000306151.4	+	3	1568	c.1504C>T	c.(1504-1506)Cca>Tca	p.P502S		NM_001040105.1	NP_001035194.1	Q685J3	MUC17_HUMAN	mucin 17, cell surface associated	502	59 X approximate tandem repeats.|Ser-rich.					extracellular region|integral to membrane|plasma membrane	extracellular matrix constituent, lubricant activity			NS(3)|breast(14)|central_nervous_system(2)|cervix(2)|endometrium(27)|haematopoietic_and_lymphoid_tissue(2)|kidney(18)|large_intestine(28)|lung(179)|ovary(19)|pancreas(1)|prostate(13)|skin(26)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(4)	343	Lung NSC(181;0.136)|all_lung(186;0.182)					TAACAGCATGCCAACCTCAAC	0.493000													6	948					0	0	1	0	0
ITGBL1	9358	broad.mit.edu	37	13	102227854	102227854	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr13:102227854C>T	ENST00000376180.3	+	4	762	c.543C>T	c.(541-543)gaC>gaT	p.D181D	ITGBL1_ENST00000376162.3_Silent_p.D88D|ITGBL1_ENST00000545560.2_Silent_p.D40D	NM_001271756.1|NM_004791.1	NP_001258685.1|NP_004782.1	O95965	ITGBL_HUMAN	integrin, beta-like 1 (with EGF-like repeat domains)	181	Cysteine-rich tandem repeats.				cell-matrix adhesion|integrin-mediated signaling pathway	extracellular region|integrin complex	binding|receptor activity			breast(1)|large_intestine(6)|lung(16)|ovary(1)|prostate(4)|skin(3)	31	all_neural(89;0.0438)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)					GTGAGTGTGACGATAGAGAAT	0.348000													11	364					0	0	1	0	0
TRANK1	9881	broad.mit.edu	37	3	36899337	36899337	+	Missense_Mutation	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr3:36899337T>C	ENST00000429976.2	-	12	1991	c.1744A>G	c.(1744-1746)Aaa>Gaa	p.K582E	TRANK1_ENST00000428977.2_Missense_Mutation_p.K32E|TRANK1_ENST00000301807.6_Missense_Mutation_p.K32E			O15050	TRNK1_HUMAN	tetratricopeptide repeat and ankyrin repeat containing 1	582					DNA repair		ATP binding|ATP-dependent DNA helicase activity|DNA binding			NS(2)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|lung(20)|ovary(1)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	73						TTGCCCTCTTTGTTCTTCAGA	0.512000													5	273					0	0	1	0	0
TVP23C	201158	broad.mit.edu	37	17	15441469	15441469	+	Splice_Site	SNP	C	C	T	rs139351610	by1000genomes	TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr17:15441469C>T	ENST00000584811.1	-	7	1815		c.e7-2		TVP23C_ENST00000225576.3_Intron|TVP23C-CDRT4_ENST00000522212.2_Intron|TVP23C_ENST00000428082.2_Splice_Site|TVP23C_ENST00000438826.3_Splice_Site|TVP23C_ENST00000519970.1_Intron					trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)																		TCCAGTGTTCCGCAAAAGACA	0.393000													4	136					0	0	1	0	0
ST8SIA4	7903	broad.mit.edu	37	5	100222198	100222198	+	Silent	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr5:100222198G>A	ENST00000231461.5	-	3	662	c.352C>T	c.(352-354)Cta>Tta	p.L118L	ST8SIA4_ENST00000507360.2_5'UTR|ST8SIA4_ENST00000451528.2_Silent_p.L118L	NM_005668.4	NP_005659.1	Q92187	SIA8D_HUMAN	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	118					axon guidance|N-glycan processing	integral to Golgi membrane	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity			NS(1)|central_nervous_system(1)|endometrium(3)|large_intestine(11)|lung(7)|stomach(1)|upper_aerodigestive_tract(1)	25		all_cancers(142;1.5e-07)|all_epithelial(76;1.43e-10)|Prostate(80;0.000644)|Lung NSC(167;0.0059)|all_lung(232;0.00914)|Ovarian(225;0.024)|Colorectal(57;0.09)|Breast(839;0.203)		COAD - Colon adenocarcinoma(37;0.00402)		GAAATGTTTAGTGTCCGGCGC	0.438000													61	206					0	0	1	0	0
TRIM55	84675	broad.mit.edu	37	8	67039513	67039513	+	Missense_Mutation	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr8:67039513T>C	ENST00000315962.4	+	1	383	c.10T>C	c.(10-12)Tct>Cct	p.S4P	TRIM55_ENST00000353317.5_Missense_Mutation_p.S4P|TRIM55_ENST00000350034.4_Missense_Mutation_p.S4P|TRIM55_ENST00000276573.7_Missense_Mutation_p.S4P	NM_184085.1	NP_908973.1	Q9BYV6	TRI55_HUMAN	tripartite motif containing 55	4						cytoplasm|microtubule|nucleus	signal transducer activity|zinc ion binding			breast(1)|central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(10)|lung(13)|ovary(1)|prostate(2)|skin(6)|upper_aerodigestive_tract(2)	39		Lung NSC(129;0.138)|all_lung(136;0.221)	Epithelial(68;0.0136)|all cancers(69;0.0582)|BRCA - Breast invasive adenocarcinoma(89;0.0628)|OV - Ovarian serous cystadenocarcinoma(28;0.0904)			GATGAGCGCATCTCTGAATTA	0.483000													32	131					0	0	1	0	0
EPHA5	2044	broad.mit.edu	37	4	66213865	66213865	+	Silent	SNP	A	A	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr4:66213865A>G	ENST00000273854.3	-	15	3165	c.2565T>C	c.(2563-2565)ttT>ttC	p.F855F	EPHA5_ENST00000354839.4_Silent_p.F833F|EPHA5_ENST00000511294.1_Silent_p.F856F|EPHA5_ENST00000432638.2_Silent_p.F692F	NM_004439.5	NP_004430.4	P54756	EPHA5_HUMAN	EPH receptor A5	855	Protein kinase.				cAMP-mediated signaling|neuron development	dendrite|external side of plasma membrane|integral to plasma membrane|neuronal cell body|perinuclear region of cytoplasm|rough endoplasmic reticulum	ATP binding|transmembrane-ephrin receptor activity			autonomic_ganglia(1)|breast(2)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(25)|liver(1)|lung(76)|ovary(3)|pancreas(1)|prostate(1)|skin(3)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	142						TGGCAGAAGTAAACTTTCGGA	0.388000										TSP Lung(17;0.13)			4	204					0	0	1	0	0
TSSC2	0	broad.mit.edu	37	11	3424149	3424149	+	RNA	SNP	C	C	T	rs112841660		TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr11:3424149C>T	ENST00000529482.1	+	0	808																											TCATAGAGGACGAAGACTTCT	0.562000													3	48					0	0	1	0	0
DSC1	1823	broad.mit.edu	37	18	28710645	28710645	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr18:28710645C>T	ENST00000257198.5	-	16	2778	c.2517G>A	c.(2515-2517)gaG>gaA	p.E839E	DSC1_ENST00000257197.3_3'UTR|RP11-408H20.2_ENST00000581836.1_RNA	NM_024421.2	NP_077739.1	Q08554	DSC1_HUMAN	desmocollin 1	839					homophilic cell adhesion	desmosome|gap junction|integral to membrane|membrane fraction	calcium ion binding			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(8)|lung(20)|ovary(3)|skin(10)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	53			OV - Ovarian serous cystadenocarcinoma(10;0.00778)			AATGTTTATGCTCCTCATCTT	0.388000													4	158					0	0	1	0	0
NR3C1	2908	broad.mit.edu	37	5	142780104	142780104	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr5:142780104C>T	ENST00000343796.2	-	2	1294	c.301G>A	c.(301-303)Gac>Aac	p.D101N	NR3C1_ENST00000394466.2_Missense_Mutation_p.D101N|NR3C1_ENST00000416954.2_Intron|NR3C1_ENST00000394464.2_Missense_Mutation_p.D101N|NR3C1_ENST00000424646.2_Missense_Mutation_p.D101N|NR3C1_ENST00000231509.3_Missense_Mutation_p.D101N|NR3C1_ENST00000415690.2_Missense_Mutation_p.D101N|NR3C1_ENST00000503201.1_Missense_Mutation_p.D101N|NR3C1_ENST00000504572.1_Missense_Mutation_p.D101N	NM_001018074.1|NM_001018075.1|NM_001018077.1	NP_001018084.1|NP_001018085.1|NP_001018087.1	P04150	GCR_HUMAN	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	101	Modulating.				chromatin modification|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|response to protein stimulus|transcription from RNA polymerase II promoter	mitochondrial matrix|nucleoplasm	glucocorticoid receptor activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|steroid binding|zinc ion binding			breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(10)|lung(7)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)	35		Acute lymphoblastic leukemia(2;3.2e-05)|all_hematologic(2;0.000361)	KIRC - Kidney renal clear cell carcinoma(527;0.00111)|Kidney(363;0.00176)		Amcinonide(DB00288)|Betamethasone(DB00443)|Budesonide(DB01222)|Dexamethasone(DB01234)|Flumethasone Pivalate(DB00663)|Flunisolide(DB00180)|Fluticasone Propionate(DB00588)|Hydrocortamate(DB00769)|Hydrocortisone(DB00741)|Loteprednol Etabonate(DB00873)|Methylprednisolone(DB00959)|Mifepristone(DB00834)|Mometasone(DB00764)|Prednisone(DB00635)	AATCCCAGGTCATTTCCCATC	0.483000													17	288					0	0	1	0	0
HMHA1	23526	broad.mit.edu	37	19	1080922	1080922	+	Silent	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr19:1080922G>A	ENST00000313093.2	+	17	2280	c.2049G>A	c.(2047-2049)ccG>ccA	p.P683P	HMHA1_ENST00000536472.1_Silent_p.P551P|HMHA1_ENST00000539243.2_Silent_p.P699P|HMHA1_ENST00000590577.1_Silent_p.P318P|HMHA1_ENST00000543365.1_Silent_p.P566P|HMHA1_ENST00000590214.1_Silent_p.P710P|HMHA1_ENST00000586866.1_Silent_p.P687P	NM_012292.3	NP_036424.2	Q92619	HMHA1_HUMAN	histocompatibility (minor) HA-1	683					regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity|metal ion binding			NS(1)|central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|lung(7)|ovary(1)|prostate(2)	16		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CCGAGCTGCCGGTGGCCGTGC	0.701000													15	25					0	0	1	0	0
AC024560.3	0	broad.mit.edu	37	3	197348668	197348668	+	RNA	SNP	C	C	G	rs79940815	by1000genomes	TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr3:197348668C>G	ENST00000418868.1	-	0	591					NR_003266.2																						ACTTGAGGCTCTGTCCACCAA	0.488000													4	250					0	0	1	0	0
GLUD1	2746	broad.mit.edu	37	10	88836407	88836407	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr10:88836407C>T	ENST00000277865.4	-	2	548	c.452G>A	c.(451-453)cGt>cAt	p.R151H	GLUD1_ENST00000537649.1_5'UTR|GLUD1_ENST00000544149.1_Missense_Mutation_p.R18H	NM_005271.3	NP_005262.1	P00367	DHE3_HUMAN	glutamate dehydrogenase 1	151					glutamate biosynthetic process|glutamate catabolic process|positive regulation of insulin secretion	mitochondrial matrix	ADP binding|ATP binding|glutamate dehydrogenase|glutamate dehydrogenase activity|GTP binding|identical protein binding|leucine binding|NAD+ binding			endometrium(3)|kidney(2)|large_intestine(4)|liver(1)|lung(11)|prostate(1)	22					L-Glutamic Acid(DB00142)|NADH(DB00157)	AGTGCTGTAACGGATACCTGG	0.403000													70	124					0	0	1	0	0
INSR	0	broad.mit.edu	37	19	7267448	7267448	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr19:7267448G>A	ENST00000341500.5	-	2	599	c.560C>T	c.(559-561)cCg>cTg	p.P187L	INSR_ENST00000302850.5_Missense_Mutation_p.P187L	NM_001079817.1	NP_001073285.1	P06213	INSR_HUMAN	insulin receptor	187	Cys-rich.				activation of MAPK activity|activation of protein kinase B activity|carbohydrate metabolic process|fibroblast growth factor receptor signaling pathway|G-protein coupled receptor protein signaling pathway|glucose homeostasis|heart morphogenesis|peptidyl-tyrosine phosphorylation|positive regulation of cell migration|positive regulation of cell proliferation|positive regulation of developmental growth|positive regulation of DNA replication|positive regulation of glucose import|positive regulation of glycogen biosynthetic process|positive regulation of glycolysis|positive regulation of MAPKKK cascade|positive regulation of mitosis|positive regulation of nitric oxide biosynthetic process|positive regulation of protein kinase B signaling cascade|positive regulation of protein phosphorylation|positive regulation of respiratory burst|protein autophosphorylation|protein heterotetramerization|regulation of embryonic development|regulation of transcription, DNA-dependent|transformation of host cell by virus	caveola|endosome membrane|insulin receptor complex|microsome	ATP binding|GTP binding|insulin binding|insulin receptor activity|insulin receptor substrate binding|insulin-like growth factor I binding|insulin-like growth factor II binding|insulin-like growth factor receptor binding|metal ion binding|phosphatidylinositol 3-kinase binding|PTB domain binding|receptor signaling protein tyrosine kinase activity|SH2 domain binding	p.P187L(4)		breast(1)|central_nervous_system(4)|endometrium(6)|kidney(2)|large_intestine(13)|lung(25)|ovary(4)|prostate(4)|skin(3)|stomach(2)|urinary_tract(2)	66					Insulin Glargine recombinant(DB00047)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)	CGCGGTACCCGGACAGATGTC	0.537000													4	150					0	0	1	0	0
DDX60	55601	broad.mit.edu	37	4	169183842	169183842	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr4:169183842G>A	ENST00000393743.3	-	23	3427	c.3136C>T	c.(3136-3138)Cgg>Tgg	p.R1046W	DDX60_ENST00000505393.1_5'UTR	NM_017631.5	NP_060101.3	Q8IY21	DDX60_HUMAN	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	1046							ATP binding|ATP-dependent helicase activity|RNA binding			breast(1)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(15)|liver(1)|lung(21)|ovary(1)|pancreas(2)|prostate(1)|skin(4)|urinary_tract(4)	63		Prostate(90;0.00876)|Renal(120;0.0183)|all_neural(102;0.0837)|Melanoma(52;0.132)		GBM - Glioblastoma multiforme(119;0.0485)		ACCTGGGCCCGAGGCCAACTT	0.378000													74	140					0	0	1	0	0
HIVEP1	3096	broad.mit.edu	37	6	12124098	12124098	+	Missense_Mutation	SNP	C	C	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr6:12124098C>A	ENST00000379388.2	+	4	4402	c.4070C>A	c.(4069-4071)cCt>cAt	p.P1357H		NM_002114.2	NP_002105.2	P15822	ZEP1_HUMAN	human immunodeficiency virus type I enhancer binding protein 1	1357					transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|protein binding|zinc ion binding			NS(1)|breast(5)|central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(11)|liver(1)|lung(31)|ovary(4)|prostate(1)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(3)	90	Breast(50;0.0639)|Ovarian(93;0.0816)	all_hematologic(90;0.117)				CTGAATGTTCCTGGATGTCAC	0.428000													4	133					0.00909568	0.00921536	1	1	0
LRRC16A	55604	broad.mit.edu	37	6	25605088	25605088	+	Missense_Mutation	SNP	A	A	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr6:25605088A>G	ENST00000329474.6	+	34	3969	c.3601A>G	c.(3601-3603)Agc>Ggc	p.S1201G		NM_001173977.1|NM_017640.5	NP_001167448.1|NP_060110.4	Q5VZK9	LR16A_HUMAN	leucine rich repeat containing 16A	1201					actin filament organization|blood coagulation|cell migration|lamellipodium assembly|ruffle organization|urate metabolic process	cytosol|lamellipodium|nucleus				breast(4)|central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(10)|lung(19)|ovary(2)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	50						CCCAGCTTTGAGCGGCGTAGA	0.493000													6	14					0	0	1	0	0
SLC6A7	6534	broad.mit.edu	37	5	149583555	149583555	+	Missense_Mutation	SNP	T	T	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr5:149583555T>G	ENST00000230671.2	+	10	1657	c.1286T>G	c.(1285-1287)cTc>cGc	p.L429R	SLC6A7_ENST00000524041.1_Missense_Mutation_p.L429R	NM_014228.3	NP_055043.2	Q99884	SC6A7_HUMAN	solute carrier family 6 (neurotransmitter transporter), member 7	429						integral to plasma membrane|membrane fraction	neurotransmitter:sodium symporter activity|proline:sodium symporter activity			NS(1)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(2)|liver(1)|lung(4)|skin(1)|stomach(1)	16		all_hematologic(541;0.224)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)		L-Proline(DB00172)	TTCTCAGGGCTCATCTGCGTG	0.582000													3	58					0	0	1	0	0
SNHG14	0	broad.mit.edu	37	15	25333948	25333948	+	RNA	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr15:25333948C>T	ENST00000546682.1	+	0	586				SNHG14_ENST00000549804.2_RNA|SNHG14_ENST00000553108.1_RNA	NR_003361.1																						AAATACTGTGCGTGGATCGAT	0.458000													76	313					0	0	1	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr2:209113112C>T	ENST00000415913.1	-	4	776	c.395G>A	c.(394-396)cGt>cAt	p.R132H	IDH1_ENST00000345146.2_Missense_Mutation_p.R132H|IDH1_ENST00000446179.1_Missense_Mutation_p.R132H			O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132			R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).|R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2774)|p.R132L(59)|p.R132V(1)|p.G131_R132>VL(1)		NS(1)|autonomic_ganglia(2)|biliary_tract(24)|bone(237)|central_nervous_system(3764)|endometrium(3)|haematopoietic_and_lymphoid_tissue(794)|kidney(2)|large_intestine(7)|lung(7)|prostate(6)|skin(5)|soft_tissue(12)|thyroid(22)|urinary_tract(1)	4887				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma								75	99					0	0	1	0	0
CAT	847	broad.mit.edu	37	11	34475370	34475370	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr11:34475370G>A	ENST00000241052.4	+	6	697	c.608G>A	c.(607-609)cGg>cAg	p.R203Q		NM_001752.3	NP_001743.1	P04040	CATA_HUMAN	catalase	203					hydrogen peroxide catabolic process|negative regulation of apoptosis|positive regulation of cell division|protein tetramerization|purine base metabolic process|purine nucleotide catabolic process|UV protection	peroxisomal matrix|peroxisomal membrane	catalase activity|heme binding|NADP binding|protein homodimerization activity			breast(1)|cervix(2)|endometrium(3)|kidney(2)|large_intestine(6)|lung(5)|ovary(2)|pancreas(1)|stomach(1)|urinary_tract(3)	26		Lung NSC(402;2.76e-08)|Acute lymphoblastic leukemia(5;0.00143)|all_hematologic(20;0.0116)|Melanoma(852;0.027)		BRCA - Breast invasive adenocarcinoma(625;0.000995)	Fomepizole(DB01213)	TTCAGTGATCGGGGGATTCCA	0.343000													76	145					0	0	1	0	0
CHRD	8646	broad.mit.edu	37	3	184104344	184104344	+	Missense_Mutation	SNP	T	T	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr3:184104344T>G	ENST00000204604.1	+	16	2243	c.1997T>G	c.(1996-1998)gTg>gGg	p.V666G	CHRD_ENST00000348986.3_Missense_Mutation_p.V626G|CHRD_ENST00000545352.1_Intron|EIF2B5_ENST00000444495.1_Intron|CHRD_ENST00000450923.1_Missense_Mutation_p.V666G	NM_003741.2	NP_003732.2	Q9H2X0	CHRD_HUMAN	chordin	666					BMP signaling pathway involved in spinal cord dorsal/ventral patterning|floor plate development|negative regulation of BMP signaling pathway|negative regulation of cell migration|positive regulation of cell adhesion|skeletal system development	extracellular space	cytokine binding			NS(1)|biliary_tract(1)|breast(2)|endometrium(2)|kidney(3)|large_intestine(5)|lung(23)|ovary(2)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	48	all_cancers(143;6.33e-11)|Ovarian(172;0.0339)		Epithelial(37;4.96e-33)|OV - Ovarian serous cystadenocarcinoma(80;2.72e-22)			GCCGAGGGGGTGCGGGCGCTG	0.726000													8	13					0	0	1	0	0
IRS1	3667	broad.mit.edu	37	2	227662549	227662549	+	Silent	SNP	T	T	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr2:227662549T>G	ENST00000305123.4	-	1	1926	c.906A>C	c.(904-906)cgA>cgC	p.R302R		NM_005544.2	NP_005535.1	P35568	IRS1_HUMAN	insulin receptor substrate 1	302	Ser-rich.				fibroblast growth factor receptor signaling pathway|glucose homeostasis|insulin receptor signaling pathway|negative regulation of insulin receptor signaling pathway|negative regulation of insulin secretion|nerve growth factor receptor signaling pathway|phosphatidylinositol 3-kinase cascade|phosphatidylinositol-mediated signaling|positive regulation of fatty acid beta-oxidation|positive regulation of glucose import|positive regulation of glycogen biosynthetic process|positive regulation of insulin receptor signaling pathway|positive regulation of phosphatidylinositol 3-kinase activity	caveola|cytosol|insulin receptor complex|microsome|nucleus	insulin receptor binding|insulin-like growth factor receptor binding|phosphatidylinositol 3-kinase binding|protein kinase C binding|SH2 domain binding|transmembrane receptor protein tyrosine kinase adaptor activity			autonomic_ganglia(1)|breast(2)|central_nervous_system(4)|endometrium(5)|kidney(4)|large_intestine(10)|lung(33)|ovary(6)|pancreas(1)|prostate(1)|urinary_tract(2)	69		Renal(207;0.023)|all_lung(227;0.0994)|all_hematologic(139;0.118)|Esophageal squamous(248;0.23)		Epithelial(121;3.03e-11)|all cancers(144;2.42e-08)|Lung(261;0.00712)|LUSC - Lung squamous cell carcinoma(224;0.0137)		CAGTGCGTGATCGGCGGGTCA	0.682000											OREG0015248	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	29	135					0	0	1	0	0
KCNK2	3776	broad.mit.edu	37	1	215408391	215408391	+	Missense_Mutation	SNP	T	T	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr1:215408391T>G	ENST00000444842.2	+	7	1334	c.1184T>G	c.(1183-1185)gTc>gGc	p.V395G	KCNK2_ENST00000391895.2_Missense_Mutation_p.V391G|KCNK2_ENST00000391894.2_Missense_Mutation_p.V380G	NM_001017425.2|NM_014217.3	NP_001017425.2|NP_055032.1	O95069	KCNK2_HUMAN	potassium channel, subfamily K, member 2	395	Essential for chloroform and halothane sensitivity (By similarity).|Required for basal channel activity (By similarity).						outward rectifier potassium channel activity			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(9)|lung(15)|upper_aerodigestive_tract(1)	30				OV - Ovarian serous cystadenocarcinoma(81;0.0399)|all cancers(67;0.0556)|GBM - Glioblastoma multiforme(131;0.068)	Dofetilide(DB00204)	GAGAGGGATGTCTTGCCTCCC	0.512000													27	155					0	0	1	0	0
TRIO	7204	broad.mit.edu	37	5	14485191	14485191	+	Missense_Mutation	SNP	G	G	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr5:14485191G>C	ENST00000344204.4	+	47	6695	c.6671G>C	c.(6670-6672)tGc>tCc	p.C2224S	TRIO_ENST00000537187.1_Missense_Mutation_p.C2224S	NM_007118.2	NP_009049.2	O75962	TRIO_HUMAN	trio Rho guanine nucleotide exchange factor	2224	PH 2.				apoptosis|axon guidance|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|transmembrane receptor protein tyrosine phosphatase signaling pathway	cytosol	ATP binding|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity			NS(2)|breast(6)|central_nervous_system(4)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(21)|lung(34)|ovary(4)|prostate(2)|skin(11)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(4)	118	Lung NSC(4;0.000742)					AGTTGCCTTTGCCTGGAGGAA	0.408000													5	228					0	0	1	0	0
CABS1	85438	broad.mit.edu	37	4	71201164	71201164	+	Silent	SNP	C	C	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr4:71201164C>G	ENST00000273936.4	+	1	467	c.408C>G	c.(406-408)tcC>tcG	p.S136S		NM_033122.3	NP_149113.3	Q96KC9	CABS1_HUMAN	calcium-binding protein, spermatid-specific 1	136						flagellum	calcium ion binding			NS(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(12)|ovary(4)|pancreas(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	33						TAGATTTTTCCACTGACATAG	0.383000													22	103					0	0	1	0	0
MCCC1	56922	broad.mit.edu	37	3	182804549	182804549	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr3:182804549C>T	ENST00000265594.4	-	4	447	c.301G>A	c.(301-303)Gct>Act	p.A101T	MCCC1_ENST00000492597.1_5'UTR|MCCC1_ENST00000539926.1_Intron	NM_020166.3	NP_064551.3	Q96RQ3	MCCA_HUMAN	methylcrotonoyl-CoA carboxylase 1 (alpha)	101	Biotin carboxylation.				biotin metabolic process|leucine catabolic process	mitochondrial inner membrane|mitochondrial matrix	ATP binding|biotin binding|biotin carboxylase activity|metal ion binding|methylcrotonoyl-CoA carboxylase activity			central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(9)|liver(1)|lung(17)|ovary(1)|pancreas(2)|prostate(1)|skin(2)	40	all_cancers(143;1.84e-14)|Ovarian(172;0.0355)		all cancers(12;1.8e-44)|Epithelial(37;3.23e-38)|LUSC - Lung squamous cell carcinoma(7;5.04e-25)|Lung(8;5.03e-23)|OV - Ovarian serous cystadenocarcinoma(80;5.07e-21)		Biotin(DB00121)	TGGGAGGGAGCGGGGCCGATG	0.453000													26	33					0	0	1	0	0
ZFP28	140612	broad.mit.edu	37	19	57066157	57066157	+	Missense_Mutation	SNP	C	C	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr19:57066157C>A	ENST00000301318.3	+	8	2074	c.2003C>A	c.(2002-2004)aCa>aAa	p.T668K	AC007228.11_ENST00000596587.1_RNA	NM_020828.1	NP_065879.1	Q8NHY6	ZFP28_HUMAN	ZFP28 zinc finger protein	668					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(2)|kidney(1)|large_intestine(14)|lung(6)|ovary(1)|prostate(3)|skin(4)|stomach(2)|upper_aerodigestive_tract(1)	35		Colorectal(82;0.000256)|Ovarian(87;0.243)		GBM - Glioblastoma multiforme(193;0.0302)		AAAACCCATACAGGAGAGAAA	0.463000													48	22					8.72198e-27	9.07558e-27	1	1	0
TMEM72	643236	broad.mit.edu	37	10	45430279	45430279	+	Silent	SNP	C	C	G			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr10:45430279C>G	ENST00000544540.1	+	4	655	c.171C>G	c.(169-171)ctC>ctG	p.L57L	TMEM72-AS1_ENST00000450287.2_RNA			A0PK05	TMM72_HUMAN	transmembrane protein 72	175						integral to membrane				breast(2)|kidney(1)|large_intestine(2)|lung(10)	15						ATGGGGCCCTCAAGGAGGGGC	0.602000													148	222					0	0	1	0	0
OSBPL10	114884	broad.mit.edu	37	3	31774883	31774883	+	Missense_Mutation	SNP	C	C	T	rs143778028		TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr3:31774883C>T	ENST00000396556.2	-	6	1083	c.961G>A	c.(961-963)Ggg>Agg	p.G321R	OSBPL10_ENST00000467647.1_5'UTR|OSBPL10_ENST00000438237.2_Missense_Mutation_p.G257R	NM_017784.4	NP_060254.2	Q9BXB5	OSB10_HUMAN	oxysterol binding protein-like 10	321					lipid transport		lipid binding	p.G321W(2)		breast(1)|endometrium(1)|kidney(1)|large_intestine(7)|lung(15)|prostate(2)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	34				STAD - Stomach adenocarcinoma(1;0.00406)		GACTTGGACCCGTGCCATCCC	0.413000													6	365					0	0	1	0	0
PTPRJ	5795	broad.mit.edu	37	11	48146663	48146663	+	Silent	SNP	C	C	A	rs142177730		TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr11:48146663C>A	ENST00000418331.2	+	6	1370	c.1018C>A	c.(1018-1020)Cga>Aga	p.R340R	PTPRJ_ENST00000440289.2_Silent_p.R340R	NM_002843.3	NP_002834.3	Q12913	PTPRJ_HUMAN	protein tyrosine phosphatase, receptor type, J	340	Fibronectin type-III 3.				contact inhibition|negative regulation of cell growth|negative regulation of cell migration|negative regulation of cell proliferation|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of MAP kinase activity|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of protein kinase B signaling cascade|negative regulation of T cell receptor signaling pathway|negative regulation of vascular permeability|platelet-derived growth factor receptor signaling pathway|positive chemotaxis|positive regulation of focal adhesion assembly|positive regulation of protein kinase B signaling cascade|positive regulation of survival gene product expression	cell surface|cell-cell junction|immunological synapse|integral to plasma membrane|ruffle membrane	beta-catenin binding|delta-catenin binding|gamma-catenin binding|mitogen-activated protein kinase binding|platelet-derived growth factor receptor binding|protein tyrosine phosphatase activity			breast(3)|endometrium(7)|kidney(7)|large_intestine(5)|lung(15)|ovary(1)|prostate(2)|skin(6)|stomach(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	52						GCCTGGCACCCGATACAATGC	0.562000													51	172					5.57489e-27	5.88037e-27	1	1	0
KCNB2	9312	broad.mit.edu	37	8	73480200	73480200	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr8:73480200C>T	ENST00000523207.1	+	2	819	c.231C>T	c.(229-231)tgC>tgT	p.C77C		NM_004770.2	NP_004761.2	Q92953	KCNB2_HUMAN	potassium voltage-gated channel, Shab-related subfamily, member 2	77					regulation of smooth muscle contraction	voltage-gated potassium channel complex	delayed rectifier potassium channel activity|protein binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(20)|liver(2)|lung(31)|ovary(2)|pancreas(3)|prostate(2)|skin(8)|upper_aerodigestive_tract(4)|urinary_tract(1)	85	Breast(64;0.137)		Epithelial(68;0.105)			TGGAAGTGTGCGACGACTATA	0.522000													4	163					0	0	1	0	0
CIC	23152	broad.mit.edu	37	19	42799051	42799051	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr19:42799051G>A	ENST00000572681.2	+	21	7321	c.7253G>A	c.(7252-7254)cGt>cAt	p.R2418H	CIC_ENST00000160740.3_Missense_Mutation_p.R1510H|CIC_ENST00000575354.2_Missense_Mutation_p.R1512H			Q96RK0	CIC_HUMAN	capicua transcriptional repressor	1512					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|protein binding			autonomic_ganglia(1)|breast(5)|central_nervous_system(32)|endometrium(10)|kidney(2)|large_intestine(7)|lung(9)|ovary(7)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	82		Prostate(69;0.00682)				TTGAAGATCCGTGAGGTGCGC	0.627000			"""Mis, F, S"""		oligodendroglioma								4	85					0	0	1	0	0
ZNF737	100129842	broad.mit.edu	37	19	20728053	20728053	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr19:20728053C>T	ENST00000427401.4	-	4	1050	c.956G>A	c.(955-957)gGc>gAc	p.G319D		NM_001159293.1	NP_001152765.1	C9JHM3	C9JHM3_HUMAN	zinc finger protein 737	319					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding			breast(2)|kidney(1)|lung(7)|ovary(1)|stomach(1)|urinary_tract(1)	13						AAAGGCTTTGCCACATTCTTC	0.418000													4	129					0	0	1	0	0
ASUN	55726	broad.mit.edu	37	12	27087520	27087520	+	Missense_Mutation	SNP	G	G	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr12:27087520G>T	ENST00000261191.7	-	3	805	c.269C>A	c.(268-270)tCt>tAt	p.S90Y	ASUN_ENST00000539625.1_Intron	NM_018164.2	NP_060634.2	Q9NVM9	M89BB_HUMAN	asunder spermatogenesis regulator	90					cell division|mitosis|regulation of mitotic cell cycle		protein binding										TTGAGTCCAAGAATTTAAAAC	0.313000													56	187					5.10508e-28	5.4596e-28	1	1	0
MOGAT3	346606	broad.mit.edu	37	7	100839216	100839216	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr7:100839216C>T	ENST00000379423.3	-	6	894	c.834G>A	c.(832-834)gcG>gcA	p.A278A	MOGAT3_ENST00000440203.2_3'UTR|MOGAT3_ENST00000223114.4_3'UTR			Q86VF5	MOGT3_HUMAN	monoacylglycerol O-acyltransferase 3	0					glycerol metabolic process|lipid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	2-acylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity			breast(1)|central_nervous_system(1)|endometrium(4)|large_intestine(3)|lung(10)|ovary(3)	22	Lung NSC(181;0.168)|all_lung(186;0.215)					AGCGAAAGGCCGCGGCCAGGC	0.627000													56	90					0	0	1	0	0
ATP6V1H	51606	broad.mit.edu	37	8	54723771	54723771	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr8:54723771G>A	ENST00000359530.2	-	7	795	c.532C>T	c.(532-534)Cgt>Tgt	p.R178C	ATP6V1H_ENST00000396774.2_Missense_Mutation_p.R178C|ATP6V1H_ENST00000355221.3_Intron|ATP6V1H_ENST00000520188.1_Missense_Mutation_p.R138C	NM_015941.3	NP_057025.2	Q9UI12	VATH_HUMAN	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	178					ATP hydrolysis coupled proton transport|cellular iron ion homeostasis|endocytosis|insulin receptor signaling pathway|interspecies interaction between organisms|regulation of defense response to virus by virus|transferrin transport|vacuolar acidification|viral reproduction	cytosol|plasma membrane|vacuolar proton-transporting V-type ATPase, V1 domain	enzyme regulator activity|protein binding|proton-transporting ATPase activity, rotational mechanism			endometrium(3)|large_intestine(5)|lung(8)|ovary(1)|urinary_tract(1)	18		all_epithelial(80;0.0487)|Lung NSC(129;0.109)|all_lung(136;0.181)	OV - Ovarian serous cystadenocarcinoma(7;2.79e-06)|Epithelial(17;0.000629)|all cancers(17;0.00359)			CCGCTACCACGCAGTTTCTAT	0.343000													4	164					0	0	1	0	0
SNX29	92017	broad.mit.edu	37	16	12662399	12662399	+	Silent	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr16:12662399G>A	ENST00000566228.1	+	21	2424	c.2355G>A	c.(2353-2355)cgG>cgA	p.R785R	CTD-3037G24.3_ENST00000564505.1_RNA|SNX29_ENST00000306030.3_Silent_p.R400R	NM_032167.3	NP_115543.3	Q8TEQ0	SNX29_HUMAN	sorting nexin 29	400					cell communication		phosphatidylinositol binding			endometrium(1)|large_intestine(1)|lung(3)|ovary(1)|prostate(1)	7						TGAACAGCCGGCCCAAAGCAG	0.622000													4	87					0	0	1	0	0
IGSF6	10261	broad.mit.edu	37	16	21658503	21658503	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr16:21658503C>T	ENST00000268389.4	-	2	439	c.378G>A	c.(376-378)ccG>ccA	p.P126P	METTL9_ENST00000358154.3_Intron|METTL9_ENST00000396014.4_Intron	NM_005849.3	NP_005840.2	O95976	IGSF6_HUMAN	immunoglobulin superfamily, member 6	126	Ig-like C2-type.				cell surface receptor linked signaling pathway|immune response	integral to plasma membrane	transmembrane receptor activity			endometrium(1)|large_intestine(1)|lung(4)|urinary_tract(1)	7				GBM - Glioblastoma multiforme(48;0.066)		CTCTCGCTTCCGGCACACTGG	0.488000													5	243					0	0	1	0	0
CADPS2	93664	broad.mit.edu	37	7	122261562	122261562	+	Silent	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr7:122261562G>A	ENST00000334010.7	-	5	1498	c.1077C>T	c.(1075-1077)tcC>tcT	p.S359S	CADPS2_ENST00000313070.7_Silent_p.S359S|CADPS2_ENST00000449022.2_Silent_p.S359S|CADPS2_ENST00000412584.2_Silent_p.S359S	NM_001167940.1	NP_001161412.1	Q86UW7	CAPS2_HUMAN	Ca++-dependent secretion activator 2	359					exocytosis|protein transport	cell junction|cytoplasmic vesicle membrane|synapse	lipid binding|metal ion binding			breast(1)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(7)|lung(26)|ovary(2)	43						GTACCACGTCGGACTTTGACA	0.393000													5	232					0	0	1	0	0
KBTBD6	89890	broad.mit.edu	37	13	41705440	41705440	+	Missense_Mutation	SNP	G	G	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr13:41705440G>T	ENST00000379485.1	-	1	1442	c.1208C>A	c.(1207-1209)aCa>aAa	p.T403K	KBTBD6_ENST00000499385.2_Missense_Mutation_p.T337K	NM_152903.4	NP_690867.3	Q86V97	KBTB6_HUMAN	kelch repeat and BTB (POZ) domain containing 6	403							protein binding	p.T403K(7)		NS(1)|breast(1)|endometrium(8)|kidney(4)|large_intestine(9)|lung(9)|ovary(1)|prostate(2)|skin(4)|urinary_tract(4)	43		Lung NSC(96;4.52e-06)|Breast(139;0.00123)|Prostate(109;0.0181)|Lung SC(185;0.0262)|Hepatocellular(98;0.114)		all cancers(112;4.08e-09)|Epithelial(112;4.74e-06)|OV - Ovarian serous cystadenocarcinoma(117;0.000131)|GBM - Glioblastoma multiforme(144;0.000876)|BRCA - Breast invasive adenocarcinoma(63;0.0673)		CCAGAGGTCTGTCCTGGGCTG	0.507000													5	252					0.000602214	0.000618273	1	1	0
CYP11A1	1583	broad.mit.edu	37	15	74637578	74637578	+	Silent	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr15:74637578C>T	ENST00000268053.6	-	3	586	c.432G>A	c.(430-432)tcG>tcA	p.S144S	CYP11A1_ENST00000541301.1_Intron|CYP11A1_ENST00000358632.4_5'UTR|CYP11A1_ENST00000419019.2_5'UTR	NM_000781.2	NP_000772.2	P05108	CP11A_HUMAN	cytochrome P450, family 11, subfamily A, polypeptide 1	144					C21-steroid hormone biosynthetic process|cholesterol metabolic process|vitamin D metabolic process|xenobiotic metabolic process	mitochondrial matrix	cholesterol monooxygenase (side-chain-cleaving) activity|electron carrier activity|heme binding			breast(1)|endometrium(2)|kidney(1)|large_intestine(7)|lung(3)|ovary(2)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	20					Aminoglutethimide(DB00357)|Cholecalciferol(DB00169)|Cimetidine(DB00501)|Clotrimazole(DB00257)|Digitoxin(DB01396)|Digoxin(DB00390)|Medroxyprogesterone(DB00603)|Ouabain(DB01092)|Progesterone(DB00396)|Testosterone(DB00624)|Trilostane(DB01108)	TCCAGGCTGCCGACTTCCTGA	0.582000													25	43					0	0	1	0	0
SULF1	23213	broad.mit.edu	37	8	70541854	70541854	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr8:70541854C>T	ENST00000260128.4	+	19	2941	c.2224C>T	c.(2224-2226)Cct>Tct	p.P742S	SULF1_ENST00000458141.2_Missense_Mutation_p.P742S|SULF1_ENST00000402687.4_Missense_Mutation_p.P742S|SULF1_ENST00000521946.1_3'UTR|SULF1_ENST00000419716.3_Missense_Mutation_p.P742S	NM_015170.2	NP_055985.2	Q8IWU6	SULF1_HUMAN	sulfatase 1	742					apoptosis|bone development|heparan sulfate proteoglycan metabolic process|kidney development|negative regulation of fibroblast growth factor receptor signaling pathway	cell surface|endoplasmic reticulum|extracellular space|Golgi stack	arylsulfatase activity|calcium ion binding			breast(2)|central_nervous_system(3)|endometrium(5)|kidney(3)|large_intestine(10)|lung(15)|ovary(3)|pancreas(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	52	Breast(64;0.0654)		Epithelial(68;0.0124)|OV - Ovarian serous cystadenocarcinoma(28;0.0265)|all cancers(69;0.0534)			GTGCAGCCTGCCTGGCCTCAC	0.537000													5	247					0	0	1	0	0
COG4	25839	broad.mit.edu	37	16	70546310	70546310	+	Silent	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr16:70546310T>C	ENST00000323786.5	-	5	591	c.570A>G	c.(568-570)aaA>aaG	p.K190K	COG4_ENST00000564653.1_Intron|COG4_ENST00000393612.4_Silent_p.K186K	NM_001195139.1|NM_015386.2	NP_001182068.1|NP_056201.2	Q9H9E3	COG4_HUMAN	component of oligomeric golgi complex 4	186					Golgi organization|Golgi vesicle prefusion complex stabilization|protein transport|retrograde vesicle-mediated transport, Golgi to ER	Golgi membrane|Golgi transport complex	protein binding			breast(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(8)|lung(12)|pancreas(1)|prostate(2)	33		Ovarian(137;0.0694)				CCTGCAGCAATTTCAGGTTGG	0.478000													18	36					0	0	1	0	0
EPX	8288	broad.mit.edu	37	17	56270829	56270829	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr17:56270829G>A	ENST00000225371.5	+	3	378	c.268G>A	c.(268-270)Gca>Aca	p.A90T		NM_000502.4	NP_000493.1	P11678	PERE_HUMAN	eosinophil peroxidase	90					hydrogen peroxide catabolic process		heme binding|peroxidase activity|protein binding			breast(2)|endometrium(9)|kidney(1)|large_intestine(9)|liver(2)|lung(20)|ovary(2)|prostate(2)|upper_aerodigestive_tract(1)	48						TGTTCGGGCCGCAGATTATAT	0.572000													56	137					0	0	1	0	0
CACUL1	143384	broad.mit.edu	37	10	120450872	120450872	+	Silent	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr10:120450872T>C	ENST00000369151.3	-	7	1413	c.930A>G	c.(928-930)ccA>ccG	p.P310P	CACUL1_ENST00000544392.1_5'UTR	NM_153810.4	NP_722517.3			CDK2-associated, cullin domain 1																		GGAGAATGTTTGGAATAAATT	0.363000													114	198					0	0	1	0	0
MPG	4350	broad.mit.edu	37	16	135641	135641	+	Silent	SNP	G	G	A	rs140510538		TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr16:135641G>A	ENST00000219431.4	+	5	993	c.762G>A	c.(760-762)ccG>ccA	p.P254P	MPG_ENST00000397817.1_Silent_p.P237P	NM_002434.3	NP_002425.2	P29372	3MG_HUMAN	N-methylpurine-DNA glycosylase	254					depurination|DNA dealkylation involved in DNA repair	nucleoplasm	alkylbase DNA N-glycosylase activity|damaged DNA binding|identical protein binding			endometrium(4)|kidney(1)|ovary(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	9		all_cancers(16;9.01e-08)|all_epithelial(16;7.64e-07)|Hepatocellular(780;0.000325)|Lung NSC(18;0.0104)|all_lung(18;0.0239)				CCAGTGAGCCGGCTGTAGTGG	0.667000								Base excision repair (BER), DNA glycosylases					10	29					0	0	1	0	0
KCNK2	3776	broad.mit.edu	37	1	215408420	215408420	+	Missense_Mutation	SNP	A	A	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr1:215408420A>T	ENST00000444842.2	+	7	1363	c.1213A>T	c.(1213-1215)Atc>Ttc	p.I405F	KCNK2_ENST00000391895.2_Missense_Mutation_p.I401F|KCNK2_ENST00000391894.2_Missense_Mutation_p.I390F	NM_001017425.2|NM_014217.3	NP_001017425.2|NP_055032.1	O95069	KCNK2_HUMAN	potassium channel, subfamily K, member 2	405	Essential for chloroform and halothane sensitivity (By similarity).|Required for basal channel activity (By similarity).						outward rectifier potassium channel activity			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(9)|lung(15)|upper_aerodigestive_tract(1)	30				OV - Ovarian serous cystadenocarcinoma(81;0.0399)|all cancers(67;0.0556)|GBM - Glioblastoma multiforme(131;0.068)	Dofetilide(DB00204)	GACTGAGAGTATCTATCTGAA	0.473000													32	184					0	0	1	0	0
FOXR2	139628	broad.mit.edu	37	X	55651077	55651077	+	Silent	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chrX:55651077T>C	ENST00000339140.3	+	1	1245	c.933T>C	c.(931-933)ctT>ctC	p.L311L		NM_198451.3	NP_940853.1	Q6PJQ5	FOXR2_HUMAN	forkhead box R2	311					embryo development|organ development|pattern specification process|regulation of sequence-specific DNA binding transcription factor activity|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			biliary_tract(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(1)|liver(1)|lung(8)|prostate(1)|skin(1)|urinary_tract(1)	19						TCTTTGATCTTTGAAATGCCA	0.478000													9	37					0	0	1	0	0
GSG1L	146395	broad.mit.edu	37	16	27856321	27856321	+	Silent	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr16:27856321G>A	ENST00000380898.2	-	4	696	c.147C>T	c.(145-147)ctC>ctT	p.L49L	GSG1L_ENST00000395724.3_Silent_p.L153L|GSG1L_ENST00000569166.1_Silent_p.L49L|GSG1L_ENST00000447459.2_Silent_p.L204L|GSG1L_ENST00000380897.3_Silent_p.L49L			Q6UXU4	GSG1L_HUMAN	GSG1-like	204						integral to membrane				endometrium(2)|large_intestine(2)|lung(8)|ovary(1)|prostate(4)	17						CCTCAGGACCGAGGCTCACGG	0.602000													13	35					0	0	1	0	0
IL27RA	9466	broad.mit.edu	37	19	14157003	14157003	+	Nonsense_Mutation	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr19:14157003G>A	ENST00000263379.2	+	7	931	c.806G>A	c.(805-807)tGg>tAg	p.W269*		NM_004843.3	NP_004834.1	Q6UWB1	I27RA_HUMAN	interleukin 27 receptor, alpha	269					cell surface receptor linked signaling pathway|immune response	integral to plasma membrane	transmembrane receptor activity			breast(3)|endometrium(3)|kidney(2)|large_intestine(8)|lung(7)|ovary(1)|skin(1)|urinary_tract(1)	26						TACAAAGTCTGGTTCTGGGTT	0.552000													132	232					0	0	1	0	0
PRKDC	5591	broad.mit.edu	37	8	48715931	48715931	+	Silent	SNP	G	G	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr8:48715931G>A	ENST00000314191.2	-	71	9911	c.9855C>T	c.(9853-9855)tgC>tgT	p.C3285C	PRKDC_ENST00000338368.3_Silent_p.C3285C|PRKDC_ENST00000523565.1_5'UTR	NM_006904.6	NP_008835.5	P78527	PRKDC_HUMAN	protein kinase, DNA-activated, catalytic polypeptide	3286	FAT.				cellular response to insulin stimulus|double-strand break repair via nonhomologous end joining|peptidyl-serine phosphorylation|positive regulation of transcription from RNA polymerase II promoter	DNA-dependent protein kinase-DNA ligase 4 complex|transcription factor complex	ATP binding|DNA binding|DNA-dependent protein kinase activity|transcription factor binding			NS(1)|autonomic_ganglia(1)|breast(2)|central_nervous_system(9)|cervix(3)|endometrium(15)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(30)|lung(56)|ovary(6)|pancreas(1)|prostate(8)|skin(7)	147		all_cancers(86;0.0336)|all_epithelial(80;0.00111)|Lung NSC(129;0.00363)|all_lung(136;0.00391)				ACCGGCTCCGGCAGTGGCTCA	0.512000								Non-homologous end-joining					5	249					0	0	1	0	0
SYNE1	23345	broad.mit.edu	37	6	152772223	152772223	+	Missense_Mutation	SNP	T	T	A			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr6:152772223T>A	ENST00000367255.5	-	26	3746	c.3145A>T	c.(3145-3147)Atg>Ttg	p.M1049L	SYNE1_ENST00000448038.1_Missense_Mutation_p.M1056L|SYNE1_ENST00000341594.5_Missense_Mutation_p.M1115L|SYNE1_ENST00000413186.2_Missense_Mutation_p.M1049L|SYNE1_ENST00000423061.1_Missense_Mutation_p.M1056L|SYNE1_ENST00000367253.4_Missense_Mutation_p.M1049L|SYNE1_ENST00000367248.3_Missense_Mutation_p.M1039L|SYNE1_ENST00000265368.4_Missense_Mutation_p.M1049L	NM_182961.3	NP_892006.3	Q8NF91	SYNE1_HUMAN	spectrin repeat containing, nuclear envelope 1	1049					cell death|cytoskeletal anchoring at nuclear membrane|Golgi organization|muscle cell differentiation|nuclear matrix anchoring at nuclear membrane	cytoskeleton|Golgi apparatus|integral to membrane|nuclear outer membrane|postsynaptic membrane|sarcomere|SUN-KASH complex	actin binding|lamin binding			NS(3)|biliary_tract(1)|breast(17)|central_nervous_system(21)|cervix(3)|endometrium(27)|haematopoietic_and_lymphoid_tissue(4)|kidney(16)|large_intestine(138)|liver(1)|lung(190)|ovary(11)|pancreas(5)|prostate(12)|skin(20)|stomach(3)|upper_aerodigestive_tract(33)|urinary_tract(19)	524		Ovarian(120;0.0955)	BRCA - Breast invasive adenocarcinoma(37;0.243)	OV - Ovarian serous cystadenocarcinoma(155;2.24e-10)		TCCTGGGGCATCAGCTTGGTC	0.453000										HNSCC(10;0.0054)			74	181					0	0	1	0	0
AGAP1	116987	broad.mit.edu	37	2	236708060	236708060	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr2:236708060C>T	ENST00000409538.1	+	8	2142	c.1646C>T	c.(1645-1647)tCg>tTg	p.S549L	AGAP1_ENST00000428334.2_Missense_Mutation_p.S123L|AGAP1_ENST00000336665.5_Missense_Mutation_p.S284L|AGAP1_ENST00000304032.7_Missense_Mutation_p.S284L|AGAP1_ENST00000409457.1_Missense_Mutation_p.S284L			Q9UPQ3	AGAP1_HUMAN	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	284	PH.				protein transport|regulation of ARF GTPase activity|small GTPase mediated signal transduction	cytoplasm	ARF GTPase activator activity|GTP binding|zinc ion binding			breast(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(12)|lung(11)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	41						TCCGTTCCATCGACTCCCAGC	0.517000													4	162					0	0	1	0	0
MUC7	4589	broad.mit.edu	37	4	71346978	71346978	+	Missense_Mutation	SNP	T	T	C			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr4:71346978T>C	ENST00000413702.1	+	4	805	c.517T>C	c.(517-519)Tct>Cct	p.S173P	MUC7_ENST00000514512.1_3'UTR|MUC7_ENST00000456088.1_Missense_Mutation_p.S173P|MUC7_ENST00000304887.5_Missense_Mutation_p.S173P	NM_001145006.1	NP_001138478.1	Q8TAX7	MUC7_HUMAN	mucin 7, secreted	173	Thr-rich.					extracellular region	protein binding	p.S173P(3)		central_nervous_system(1)|endometrium(3)|kidney(5)|large_intestine(2)|lung(23)|ovary(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	42			Lung(101;0.211)			ACCCACACCTTCTGCAACTAC	0.522000													5	217					0	0	1	0	0
RP11-44F14.1	0	broad.mit.edu	37	16	53404691	53404691	+	RNA	SNP	C	C	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr16:53404691C>T	ENST00000565421.1	-	0	350																											AAATAAGCCTCCATTTCAGAG	0.358000													14	36					0	0	1	0	0
ZNF292	23036	broad.mit.edu	37	6	87966803	87966806	+	Frame_Shift_Del	DEL	GTTT	GTTT	-			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr6:87966803_87966806delGTTT	ENST00000369577.3	+	8	3499_3502	c.3456_3459delGTTT	c.(3454-3459)aafs	p.KF1152fs	ZNF292_ENST00000339907.4_Frame_Shift_Del_p.KF1147fs	NM_015021.1	NP_055836.1	O60281	ZN292_HUMAN	zinc finger protein 292	1152					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(16)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(27)|lung(21)|ovary(4)|prostate(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	89		all_cancers(76;3.82e-09)|Prostate(29;1.34e-10)|Acute lymphoblastic leukemia(125;2.17e-10)|all_hematologic(105;1.08e-06)|all_epithelial(107;5.31e-05)		BRCA - Breast invasive adenocarcinoma(108;0.0199)		ATAATGGAAAGTTTGTTTATTTTT	0.402													30	88	---	---	---	---					
RP11-165I9.6	0	broad.mit.edu	37	13	25780715	25780715	+	RNA	DEL	T	T	-			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr13:25780715delT	ENST00000435725.2	-	0	195																											ttaataaaaattttaaaaaaa	0.378													3	5	---	---	---	---					
ARGLU1	55082	broad.mit.edu	37	13	107219953	107219955	+	In_Frame_Del	DEL	CTC	CTC	-			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr13:107219953_107219955delCTC	ENST00000400198.3	-	1	557_559	c.313_315delGAG	c.(313-315)del	p.E105del		NM_018011.3	NP_060481.3	Q9NWB6	ARGL1_HUMAN	arginine and glutamate rich 1	105	Glu-rich.									large_intestine(1)|lung(5)|pancreas(1)	7	Lung NSC(43;0.015)|all_neural(89;0.0741)|Lung SC(71;0.14)|Medulloblastoma(90;0.169)					CCGCTTTCTTCTCCTCCTCCTCT	0.714													51	125	---	---	---	---					
UBR7	55148	broad.mit.edu	37	14	93693343	93693345	+	In_Frame_Del	DEL	AGA	AGA	-			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr14:93693343_93693345delAGA	ENST00000013070.6	+	11	1476_1478	c.1240_1242delAGA	c.(1240-1242)del	p.R416del	UBR7_ENST00000416753.1_In_Frame_Del_p.R340del	NM_175748.3	NP_786924.2	Q8N806	UBR7_HUMAN	ubiquitin protein ligase E3 component n-recognin 7 (putative)	416							ubiquitin-protein ligase activity|zinc ion binding			breast(2)|endometrium(2)|large_intestine(2)|lung(12)|urinary_tract(1)	19						GTCAAAAAAGAGAAGAAGAGTGG	0.374													38	82	---	---	---	---					
UBE2Q2P3	0	broad.mit.edu	37	15	83040943	83040944	+	RNA	INS	-	-	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr15:83040943_83040944insT	ENST00000558477.1	+	0	233					NR_004847.2																						GAACAAAAATCTTTTTTTTTTT	0.312													4	3	---	---	---	---					
LL22NC03-86D4.1	0	broad.mit.edu	37	22	34492089	34492090	+	RNA	INS	-	-	T			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr22:34492089_34492090insT	ENST00000412218.1	+	0	114																											ctgccttgctgtttTTTTTTGT	0.366													3	3	---	---	---	---					
TCF20	6942	broad.mit.edu	37	22	42605990	42605992	+	In_Frame_Del	DEL	CTG	CTG	-			TCGA-S9-A6WD-01A-12D-A33T-08	TCGA-S9-A6WD-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d203973d-84e1-49c8-ab52-9f8b466dd5ed	7c75a779-b0bd-4575-ab5d-a9d3c801f219	g.chr22:42605990_42605992delCTG	ENST00000359486.3	-	1	5456_5458	c.5320_5322delCAG	c.(5320-5322)del	p.Q1774del	TCF20_ENST00000335626.4_In_Frame_Del_p.Q1774del|TCF20_ENST00000404876.1_In_Frame_Del_p.Q75del	NM_005650.1	NP_005641.1	Q9UGU0	TCF20_HUMAN	transcription factor 20 (AR1)	1774					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|transcription coactivator activity|zinc ion binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(7)|large_intestine(13)|lung(22)|ovary(5)|prostate(1)|skin(2)|soft_tissue(1)|upper_aerodigestive_tract(2)|urinary_tract(5)	66						TCTGCTCCTTCTGCTGCTGCTGC	0.601													7	254	---	---	---	---