Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	ACHILLES_Top_Genes	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PRAMEF1	65121	broad.mit.edu	37	1	12855993	12855993	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:12855993G>A	uc001auj.1	+	4	1376	c.1273G>A	c.(1273-1275)GTC>ATC	p.V425I		NM_023013	NP_075389	O95521	PRAM1_HUMAN	PRAME family member 1	425											0	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.00143)|all_lung(284;0.00181)|Colorectal(325;0.00215)|Breast(348;0.0042)|Myeloproliferative disorder(586;0.0393)|Hepatocellular(190;0.0623)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00812)|Colorectal(212;4.88e-06)|Kidney(185;4.89e-05)|KIRC - Kidney renal clear cell carcinoma(229;0.000194)|COAD - Colon adenocarcinoma(227;0.000241)|BRCA - Breast invasive adenocarcinoma(304;0.000293)|STAD - Stomach adenocarcinoma(313;0.0072)|READ - Rectum adenocarcinoma(331;0.0649)		CTTGGTTCGTGTCAATTGGGA	0.577			NA											27	198					0	0	0.01441	0	0
SPEN	23013	broad.mit.edu	37	1	16258564	16258564	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:16258564G>A	uc001axk.1	+	11	6033	c.5829G>A	c.(5827-5829)GCG>GCA	p.A1943A	SPEN_uc010obp.1_Silent_p.A1902A	NM_015001	NP_055816	Q96T58	MINT_HUMAN	spen homolog, transcriptional regulator	1943	Potential.				interspecies interaction between organisms|negative regulation of transcription, DNA-dependent|Notch signaling pathway	nucleus	nucleotide binding|protein binding|RNA binding			ovary(6)|breast(3)|lung(2)|skin(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)	15		Colorectal(325;0.000258)|Breast(348;0.000278)|Lung NSC(340;0.000419)|Renal(390;0.000518)|all_lung(284;0.000567)|Ovarian(437;0.0129)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0185)|Colorectal(212;5.96e-07)|COAD - Colon adenocarcinoma(227;3.11e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000115)|Kidney(64;0.000212)|KIRC - Kidney renal clear cell carcinoma(64;0.003)|STAD - Stomach adenocarcinoma(313;0.013)|READ - Rectum adenocarcinoma(331;0.0681)		AGGCTGCAGCGGTTCCCACCA	0.587			NA											10	57					0	0	0.001855	0	0
CPT2	1376	broad.mit.edu	37	1	53668099	53668099	+	Missense_Mutation	SNP	C	C	T	rs74315294	byFrequency	TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:53668099C>T	uc001cvb.3	+	3	853	c.338C>T	c.(337-339)TCG>TTG	p.S113L		NM_000098	NP_000089	P23786	CPT2_HUMAN	carnitine O-palmitoyltransferase precursor	113	Mitochondrial matrix (By similarity).		S -> L (in CPT2D; muscular form. Frequent mutation, may be a polymorphism as it found in some 'normal' cDNA seqeuences).		carnitine shuttle|fatty acid beta-oxidation|regulation of fatty acid oxidation	mitochondrial inner membrane	carnitine O-palmitoyltransferase activity				0					L-Carnitine(DB00583)|Perhexiline(DB01074)	AGCTACATTTCGGGTAGGTAG	0.418			NA											5	63					0	0	0.001168	0	0
LEPROT	54741	broad.mit.edu	37	1	65895546	65895546	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:65895546G>T	uc001dcf.2	+	3	183	c.94G>T	c.(94-96)GTT>TTT	p.V32F	LEPR_uc001dcg.2_Intron|LEPR_uc001dch.2_Intron|LEPR_uc001dci.2_Intron|LEPR_uc009waq.2_Intron|LEPROT_uc009wap.2_Missense_Mutation_p.V41F	NM_017526	NP_059996	O15243	OBRG_HUMAN	leptin receptor gene-related protein	32	Helical; (Potential).					endosome membrane|Golgi membrane|integral to plasma membrane					0				OV - Ovarian serous cystadenocarcinoma(397;0.00722)|KIRC - Kidney renal clear cell carcinoma(1967;0.094)		AACTGACAGCGTTTACTGGCC	0.398			NA											28	131					9.04072e-19	1.39985e-18	0.003271	1	0
C1orf161	126868	broad.mit.edu	37	1	116675911	116675911	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:116675911C>A	uc001egc.1	+	7	1279	c.1014C>A	c.(1012-1014)GCC>GCA	p.A338A		NM_152367	NP_689580	Q8N8X9	MB213_HUMAN	hypothetical protein LOC126868	338				T -> A (in Ref. 1; BAC04682 and 3; AAI28150).							0	Lung SC(450;0.184)	all_cancers(81;0.00142)|all_lung(203;0.000139)|all_epithelial(167;0.000401)|Lung NSC(69;0.000705)		Lung(183;0.0171)|Colorectal(144;0.0686)|LUSC - Lung squamous cell carcinoma(189;0.0903)|all cancers(265;0.108)|COAD - Colon adenocarcinoma(174;0.111)|Epithelial(280;0.12)		TTCAGTGCACCAACCCGACTG	0.582			NA											6	130					8.12818e-05	9.21621e-05	0.001984	1	0
PKLR	5313	broad.mit.edu	37	1	155264336	155264336	+	Missense_Mutation	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:155264336A>G	uc001fkb.3	-	6	941	c.902T>C	c.(901-903)CTG>CCG	p.L301P	RAG1AP1_uc010pey.1_Intron|PKLR_uc001fka.3_Missense_Mutation_p.L270P	NM_000298	NP_000289	P30613	KPYR_HUMAN	pyruvate kinase, liver and RBC isoform 1	301					endocrine pancreas development|energy reserve metabolic process|glycolysis|positive regulation of cellular metabolic process	cytosol	ATP binding|magnesium ion binding|potassium ion binding|pyruvate kinase activity			skin(4)|ovary(1)	5	all_lung(78;6.99e-23)|Hepatocellular(266;0.0877)|all_hematologic(923;0.145)		Epithelial(20;3.18e-10)|all cancers(21;7.9e-10)|BRCA - Breast invasive adenocarcinoma(34;0.00116)|LUSC - Lung squamous cell carcinoma(543;0.127)		Pyruvic acid(DB00119)	TTCCGGACCCAGAGCAGCCCT	0.612			NA											7	37					0	0	0.00308	0	0
CD244	51744	broad.mit.edu	37	1	160802351	160802351	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:160802351C>T	uc009wtq.2	-	8	1168	c.990G>A	c.(988-990)AAG>AAA	p.K330K	CD244_uc001fxa.2_Silent_p.K325K|CD244_uc009wtp.2_RNA|CD244_uc009wtr.2_Silent_p.K233K	NM_016382	NP_057466	Q9BZW8	CD244_HUMAN	CD244 natural killer cell receptor 2B4	330	Cytoplasmic (Potential).				blood coagulation|leukocyte migration	integral to membrane|plasma membrane	protein binding|receptor activity			ovary(1)	1	all_cancers(52;2.72e-17)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.00737)			TGTGGTTCCTCTTCCTGGATC	0.433			NA											11	70					0	0	0.008291	0	0
CR2	1380	broad.mit.edu	37	1	207642509	207642509	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:207642509G>A	uc001hfw.2	+	5	843	c.749G>A	c.(748-750)GGC>GAC	p.G250D	CR2_uc001hfv.2_Missense_Mutation_p.G250D|CR2_uc009xch.2_Missense_Mutation_p.G250D|CR2_uc009xci.1_5'Flank	NM_001877	NP_001868	P20023	CR2_HUMAN	complement component (3d/Epstein Barr virus)	250	Sushi 4.|Extracellular (Potential).				complement activation, classical pathway|innate immune response	integral to membrane|plasma membrane	complement receptor activity|protein homodimerization activity			upper_aerodigestive_tract(3)|skin(3)|urinary_tract(1)|ovary(1)	8						CGACTGCAAGGCCCACCTTCT	0.473			NA											34	173					0	0	0.011902	0	0
SLC30A10	55532	broad.mit.edu	37	1	220088985	220088985	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:220088985G>T	uc001hlw.2	-	4	1475	c.1264C>A	c.(1264-1266)CTG>ATG	p.L422M	SLC30A10_uc001hlu.1_Intron|SLC30A10_uc001hlv.2_Missense_Mutation_p.L177M|SLC30A10_uc001hlx.2_Missense_Mutation_p.L197M	NM_018713	NP_061183	Q6XR72	ZNT10_HUMAN	solute carrier family 30 (zinc transporter),	422	Cytoplasmic (Potential).				zinc ion transport	integral to membrane|plasma membrane	cation transmembrane transporter activity				0				GBM - Glioblastoma multiforme(131;0.051)|all cancers(67;0.209)		ACGTGAGCCAGAGGCAGTGCC	0.567	Colon(76;360 1614 43677 51136)		NA											13	53					1.49906e-05	1.755e-05	0.00245	1	0
AIDA	64853	broad.mit.edu	37	1	222860943	222860943	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:222860943G>A	uc001hnn.2	-	5	552	c.347C>T	c.(346-348)CCA>CTA	p.P116L	AIDA_uc001hno.2_RNA|AIDA_uc010pus.1_Missense_Mutation_p.P92L	NM_022831	NP_073742	Q96BJ3	AIDA_HUMAN	axin interactor, dorsalization associated	116					dorsal/ventral pattern formation|negative regulation of JNK cascade|negative regulation of JUN kinase activity|regulation of protein homodimerization activity						0						TTACCTTAATGGGACAGGCTG	0.269			NA											9	70					0	0	0.008291	0	0
AHCTF1	25909	broad.mit.edu	37	1	247014516	247014516	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr1:247014516C>A	uc001ibu.1	-	32	4799	c.4792G>T	c.(4792-4794)GGT>TGT	p.G1598C	AHCTF1_uc001ibv.1_Missense_Mutation_p.G1607C|AHCTF1_uc009xgs.1_Missense_Mutation_p.G459C|AHCTF1_uc001ibw.1_RNA	NM_015446	NP_056261	Q8WYP5	ELYS_HUMAN	transcription factor ELYS	1598	Mediates transcriptional activity (By similarity).|Necessary for nuclear localization (By similarity).				cytokinesis|mitotic prometaphase|mRNA transport|nuclear pore complex assembly|protein transport|transmembrane transport	condensed chromosome kinetochore|cytosol|nuclear matrix|nuclear membrane|nuclear pore|nucleoplasm	DNA binding			ovary(5)|skin(2)	7	all_cancers(71;3.05e-05)|all_epithelial(71;6.72e-06)|Ovarian(71;0.0173)|Breast(184;0.0318)|all_lung(81;0.0458)|Lung NSC(105;0.0518)	all_cancers(173;0.0266)	OV - Ovarian serous cystadenocarcinoma(106;0.00271)			CCTTCTTCACCTTCCAATATC	0.413	Colon(145;197 1800 4745 15099 26333)		NA											15	43					6.94344e-10	9.614e-10	0.006122	1	0
SPAG6	9576	broad.mit.edu	37	10	22675764	22675764	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr10:22675764G>T	uc001iri.2	+	5	696	c.554G>T	c.(553-555)AGG>ATG	p.R185M	SPAG6_uc001irj.2_Missense_Mutation_p.R185M|SPAG6_uc010qct.1_Missense_Mutation_p.R155M|SPAG6_uc009xkh.2_Missense_Mutation_p.R163M	NM_012443	NP_036575	O75602	SPAG6_HUMAN	sperm associated antigen 6 isoform 1	185	ARM 4.			R -> G (in Ref. 7; AAH30585).	cell projection organization|spermatid development	axoneme|cilium|cytoplasm|flagellum|microtubule	binding			breast(1)	1						GCTTTGAAAAGGATTGCTGCT	0.473			NA											19	79					1.50039e-11	2.18239e-11	0.012319	1	0
ARMC3	219681	broad.mit.edu	37	10	23235079	23235079	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr10:23235079C>A	uc001irm.3	+	3	138	c.55C>A	c.(55-57)CCA>ACA	p.P19T	ARMC3_uc010qcv.1_Missense_Mutation_p.P19T|ARMC3_uc010qcw.1_Intron	NM_173081	NP_775104	Q5W041	ARMC3_HUMAN	armadillo repeat containing 3	19	ARM 1.						binding				0						TCAGTTTGACCCATTAATGAT	0.308			NA											5	39					3.59834e-05	4.14528e-05	0.001168	1	0
GRID1	2894	broad.mit.edu	37	10	87628808	87628808	+	Missense_Mutation	SNP	G	G	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr10:87628808G>C	uc001kdl.1	-	6	1011	c.910C>G	c.(910-912)CTG>GTG	p.L304V	GRID1_uc009xsu.1_RNA	NM_017551	NP_060021	Q9ULK0	GRID1_HUMAN	glutamate receptor, ionotropic, delta 1	304	Extracellular (Potential).					cell junction|integral to membrane|outer membrane-bounded periplasmic space|postsynaptic membrane	extracellular-glutamate-gated ion channel activity|ionotropic glutamate receptor activity			ovary(5)|upper_aerodigestive_tract(2)|large_intestine(2)|central_nervous_system(1)	10					L-Glutamic Acid(DB00142)	TCGCAGAGCAGGGAGGAGATG	0.577			NA								Multiple Myeloma(13;0.14)			16	75					0	0	0.00499	0	0
C10orf96	374355	broad.mit.edu	37	10	118137968	118137968	+	Silent	SNP	T	T	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr10:118137968T>C	uc001lck.2	+	8	938	c.687T>C	c.(685-687)GAT>GAC	p.D229D		NM_198515	NP_940917	P0C7W6	CJ096_HUMAN	hypothetical protein LOC374355	229	Potential.									ovary(2)	2		Lung NSC(174;0.204)|all_lung(145;0.248)		all cancers(201;0.014)		ATAAGGAAGATGACATGGAAA	0.274			NA											8	51					0	0	0.006214	0	0
C10orf90	118611	broad.mit.edu	37	10	128153375	128153375	+	Missense_Mutation	SNP	C	C	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr10:128153375C>G	uc001ljq.2	-	4	1545	c.1424G>C	c.(1423-1425)AGC>ACC	p.S475T	C10orf90_uc001ljp.2_Intron|C10orf90_uc010qum.1_Missense_Mutation_p.S572T|C10orf90_uc009yao.2_3'UTR|C10orf90_uc001ljo.2_5'Flank	NM_001004298	NP_001004298	Q96M02	CJ090_HUMAN	hypothetical protein LOC118611	475										ovary(1)|skin(1)	2		all_epithelial(44;4.51e-05)|all_lung(145;0.0068)|Lung NSC(174;0.0105)|Colorectal(57;0.0848)|all_neural(114;0.0936)|Breast(234;0.203)		COAD - Colon adenocarcinoma(40;0.0442)|Colorectal(40;0.0479)		TTTCAGGAAGCTTTGATGTCG	0.473			NA											6	39					0	0	0.001168	0	0
CDHR5	53841	broad.mit.edu	37	11	619514	619514	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr11:619514G>A	uc001lqj.2	-	11	1358	c.1253C>T	c.(1252-1254)ACC>ATC	p.T418I	CDHR5_uc001lqk.2_Missense_Mutation_p.T418I|CDHR5_uc009ycc.2_Missense_Mutation_p.T252I|CDHR5_uc009ycd.2_Missense_Mutation_p.T418I|CDHR5_uc001lql.2_Missense_Mutation_p.T418I|CDHR5_uc001lqm.2_Missense_Mutation_p.T252I|CDHR5_uc009yce.1_Missense_Mutation_p.T387I	NM_021924	NP_068743	Q9HBB8	CDHR5_HUMAN	mucin and cadherin-like isoform 1	418	Cadherin 4.|Extracellular (Potential).				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0						TGTGGTGGTGGTCAGCACAAC	0.597			NA											25	144					0	0	0.004289	0	0
LDHA	3939	broad.mit.edu	37	11	18418443	18418443	+	Silent	SNP	C	C	A	rs11553865		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr11:18418443C>A	uc001mok.3	+	2	326	c.54C>A	c.(52-54)ACC>ACA	p.T18T	LDHA_uc010rdc.1_Silent_p.T18T|LDHA_uc009yhn.2_Silent_p.T18T|LDHA_uc009yho.2_5'UTR|LDHA_uc001mol.3_Silent_p.T18T|LDHA_uc010rdd.1_Silent_p.T47T	NM_005566	NP_005557	P00338	LDHA_HUMAN	lactate dehydrogenase A isoform 1	18					glycolysis|pyruvate metabolic process	cytosol	L-lactate dehydrogenase activity|protein binding			central_nervous_system(3)	3					NADH(DB00157)	AAGAACAGACCCCCCAGAATA	0.418			NA											11	79					2.27111e-07	2.92e-07	0.013537	1	0
PCNXL3	399909	broad.mit.edu	37	11	65393401	65393401	+	Silent	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr11:65393401A>G	uc001oey.2	+	20	3255	c.3255A>G	c.(3253-3255)GCA>GCG	p.A1085A	PCNXL3_uc009yqn.2_Silent_p.A45A|PCNXL3_uc001oez.2_5'Flank	NM_032223	NP_115599	Q9H6A9	PCX3_HUMAN	pecanex-like 3	1085	Helical; (Potential).					integral to membrane					0						TGTTGTACGCACTGGCTGGGG	0.632			NA									OREG0021084	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	11	50					0	0	0.00245	0	0
UBTFL1	642623	broad.mit.edu	37	11	89819380	89819380	+	Missense_Mutation	SNP	A	A	G	rs75726606		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr11:89819380A>G	uc010rub.1	+	1	263	c.263A>G	c.(262-264)AAC>AGC	p.N88S		NM_001143975	NP_001137447	P0CB47	UBFL1_HUMAN	upstream binding transcription factor, RNA	88					multicellular organismal development	cytoplasm|nucleus	DNA binding				0						AAAAAGATGAACAAAAGCCAA	0.413			NA											3	19					0	0	0.001168	0	0
SIDT2	51092	broad.mit.edu	37	11	117063023	117063023	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr11:117063023C>T	uc001pqh.1	+	20	1967	c.1926C>T	c.(1924-1926)ATC>ATT	p.I642I	SIDT2_uc010rxe.1_Silent_p.I642I|SIDT2_uc001pqg.2_Silent_p.I663I|SIDT2_uc001pqi.1_Silent_p.I639I|SIDT2_uc001pqj.1_5'Flank	NM_001040455	NP_001035545	Q8NBJ9	SIDT2_HUMAN	SID1 transmembrane family, member 2 precursor	642	Helical; (Potential).					integral to membrane|lysosomal membrane					0	all_hematologic(175;0.0487)	Breast(348;0.00908)|Medulloblastoma(222;0.0425)|all_hematologic(192;0.196)|all_neural(223;0.234)		BRCA - Breast invasive adenocarcinoma(274;1.69e-05)|Epithelial(105;0.000219)|all cancers(92;0.00144)		TCATTCACATCATCGCCACCC	0.637			NA											7	99					0	0	0.004482	0	0
OR8D4	338662	broad.mit.edu	37	11	123777516	123777516	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr11:123777516C>A	uc010saa.1	+	1	378	c.378C>A	c.(376-378)ATC>ATA	p.I126I		NM_001005197	NP_001005197	Q8NGM9	OR8D4_HUMAN	olfactory receptor, family 8, subfamily D,	126	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(1)	1		Breast(109;0.00867)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.22)		BRCA - Breast invasive adenocarcinoma(274;4.93e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0409)		ACGTGGCCATCTGCAGCCCAC	0.502			NA											16	69					3.41278e-10	4.81805e-10	0.00499	1	0
KRAS	3845	broad.mit.edu	37	12	25398284	25398284	+	Missense_Mutation	SNP	C	C	G	rs121913529		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr12:25398284C>G	uc001rgp.1	-	2	216	c.35G>C	c.(34-36)GGT>GCT	p.G12A	KRAS_uc001rgq.1_Missense_Mutation_p.G12A|KRAS_uc001rgr.2_RNA	NM_033360	NP_203524	P01116	RASK_HUMAN	c-K-ras2 protein isoform a precursor	12	GTP.		G -> D (in pancreatic carcinoma, GASC and lung carcinoma; somatic mutation).|G -> R (in lung cancer and bladder cancer; somatic mutation).|G -> S (in lung carcinoma and GASC; somatic mutation).|G -> A (in a colorectal cancer sample; somatic mutation).|G -> C (in lung carcinoma; somatic mutation).|G -> V (in lung carcinoma, pancreatic carcinoma, colon cancer and GASC; somatic mutation).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	plasma membrane	GTP binding|GTPase activity|protein binding	p.G12D(7175)|p.G12V(4780)|p.G12C(2482)|p.G12A(1180)|p.G12S(1119)|p.G12R(691)|p.G12?(50)|p.G12F(34)|p.G12N(6)|p.G12G(6)|p.G12L(5)|p.G12I(4)|p.G12_G13insG(4)|p.G12E(3)|p.G12W(3)|p.A11_G12insGA(2)|p.G12Y(2)|p.G12fs*3(1)		large_intestine(12391)|pancreas(3285)|lung(2847)|biliary_tract(521)|ovary(443)|endometrium(339)|haematopoietic_and_lymphoid_tissue(318)|stomach(203)|thyroid(149)|prostate(85)|soft_tissue(77)|small_intestine(62)|upper_aerodigestive_tract(59)|cervix(49)|urinary_tract(48)|skin(38)|liver(31)|breast(28)|testis(17)|oesophagus(15)|central_nervous_system(9)|peritoneum(6)|salivary_gland(6)|kidney(5)|gastrointestinal_tract_(site_indeterminate)(5)|thymus(5)|eye(4)|autonomic_ganglia(2)|bone(2)|genital_tract(1)|penis(1)|adrenal_gland(1)	21052	all_cancers(2;1e-35)|all_epithelial(2;1.97e-38)|all_lung(3;2.1e-23)|Lung NSC(3;1.16e-22)|Acute lymphoblastic leukemia(6;0.00231)|all_hematologic(7;0.00259)|Melanoma(3;0.0301)|Colorectal(261;0.11)|Ovarian(17;0.12)		OV - Ovarian serous cystadenocarcinoma(3;1.23e-21)|Epithelial(3;1.31e-20)|all cancers(3;5.45e-18)|STAD - Stomach adenocarcinoma(2;2.68e-05)			GCCTACGCCACCAGCTCCAAC	0.348	Pancreas(8;6 143 191 305 2070 2426 4376 10944 11745 26467 38091 50869)	G12D(HPAC_PANCREAS)|G12V(SW403_LARGE_INTESTINE)|G12D(HPAFII_PANCREAS)|G12D(PANC0403_PANCREAS)|G12D(KOPN8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(KMS28BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12V(NCIH441_LUNG)|G12D(SU8686_PANCREAS)|G12D(SUIT2_PANCREAS)|G12D(PK1_PANCREAS)|G12V(KP3_PANCREAS)|G12D(PANC0813_PANCREAS)|G12A(SW1116_LARGE_INTESTINE)|G12D(LS180_LARGE_INTESTINE)|G12V(NCIH727_LUNG)|G12V(PATU8988S_PANCREAS)|G12V(CAPAN2_PANCREAS)|G12D(KP4_PANCREAS)|G12D(LS513_LARGE_INTESTINE)|G12D(SNUC2A_LARGE_INTESTINE)|G12V(SW480_LARGE_INTESTINE)|G12V(COLO668_LUNG)|G12D(COLO678_LARGE_INTESTINE)|G12V(RERFLCAD2_LUNG)|G12D(PANC0203_PANCREAS)|G12V(CFPAC1_PANCREAS)|G12V(SW900_LUNG)|G12V(LCLC97TM1_LUNG)|G12V(SW620_LARGE_INTESTINE)|G12A(MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12V(SH10TC_STOMACH)|G12V(A498_KIDNEY)|G12D(PK59_PANCREAS)|G12D(HEC1A_ENDOMETRIUM)|G12D(PANC0504_PANCREAS)|G12V(SNGM_ENDOMETRIUM)|G12A(RERFLCAD1_LUNG)|G12A(KPNSI9S_AUTONOMIC_GANGLIA)|G12D(ASPC1_PANCREAS)|G12A(RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12V(RCM1_LARGE_INTESTINE)|G12V(CORL23_LUNG)|G12D(SW1990_PANCREAS)|G12D(HEYA8_OVARY)|G12A(NCIH1573_LUNG)|G12A(NCIH2009_LUNG)|G12V(HUPT4_PANCREAS)|G12D(KARPAS620_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12D(HEC50B_ENDOMETRIUM)|G12V(YAPC_PANCREAS)|G12V(NCIH2444_LUNG)|G12V(HCC56_LARGE_INTESTINE)|G12D(MCAS_OVARY)|G12V(DANG_PANCREAS)|G12V(SHP77_LUNG)|G12D(AGS_STOMACH)|G12D(SKLU1_LUNG)|G12V(QGP1_PANCREAS)|G12D(L33_PANCREAS)|G12V(PANC0327_PANCREAS)|G12D(PANC1_PANCREAS)|G12V(RKN_OVARY)|G12V(PATU8902_PANCREAS)	119	Mis		pancreatic|colorectal|lung|thyroid|AML|others				Cardiofaciocutaneous_syndrome|Noonan_syndrome	TSP Lung(1;<1E-08)|Multiple Myeloma(2;<1E-6)			9	19					0	0	0.010729	0	0
ALG10	84920	broad.mit.edu	37	12	34179154	34179154	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr12:34179154G>T	uc001rlm.2	+	3	1045	c.726G>T	c.(724-726)ATG>ATT	p.M242I		NM_032834	NP_116223	Q5BKT4	AG10A_HUMAN	asparagine-linked glycosylation 10 homolog	242	Cytoplasmic (Potential).				dolichol-linked oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine	endoplasmic reticulum membrane|integral to membrane	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity			skin(1)	1	Lung NSC(5;3.82e-05)|Acute lymphoblastic leukemia(23;0.0142)|all_hematologic(23;0.0429)	Lung NSC(34;0.204)|all_lung(34;0.235)				CTTATTCCATGTCCTTTAAAA	0.368			NA											25	139					7.38237e-10	1.01244e-09	0.00632	1	0
KDM2B	84678	broad.mit.edu	37	12	121947779	121947779	+	Missense_Mutation	SNP	T	T	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr12:121947779T>A	uc001uat.2	-	11	1342	c.1238A>T	c.(1237-1239)GAG>GTG	p.E413V	KDM2B_uc001uar.2_Missense_Mutation_p.E4V|KDM2B_uc001uas.2_Missense_Mutation_p.E382V|KDM2B_uc001uau.2_Missense_Mutation_p.E296V|KDM2B_uc001uav.3_Missense_Mutation_p.E323V	NM_032590	NP_115979	Q8NHM5	KDM2B_HUMAN	F-box and leucine-rich repeat protein 10 isoform	413	Glu-rich.				embryonic camera-type eye morphogenesis|fourth ventricle development|histone H2A monoubiquitination|initiation of neural tube closure|lateral ventricle development|midbrain development|midbrain-hindbrain boundary morphogenesis|negative regulation of neural precursor cell proliferation|negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter|spermatogenesis|third ventricle development|transcription, DNA-dependent	nucleolus	DNA binding|histone demethylase activity (H3-K36 specific)|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|protein binding|rRNA binding|zinc ion binding			ovary(1)|skin(1)	2						ATCACAGGCCTCCTCCTCCAT	0.542			NA											10	40					0	0	0.010729	0	0
IFT88	8100	broad.mit.edu	37	13	21166516	21166516	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr13:21166516C>T	uc001unh.2	+	9	794	c.398C>T	c.(397-399)TCC>TTC	p.S133F	IFT88_uc001uni.2_Missense_Mutation_p.S124F|IFT88_uc001unj.2_Missense_Mutation_p.S123F|IFT88_uc010tcq.1_Missense_Mutation_p.S104F	NM_175605	NP_783195	Q13099	IFT88_HUMAN	intraflagellar transport 88 homolog isoform 1	133					cilium morphogenesis	centriole|intraflagellar transport particle B|microtubule basal body|microtubule-based flagellum	protein binding			ovary(1)	1		all_cancers(29;5.79e-25)|all_epithelial(30;2.57e-20)|all_lung(29;3.13e-16)|Lung SC(185;0.0262)|Ovarian(182;0.0825)|Hepatocellular(188;0.244)		all cancers(112;0.000667)|Epithelial(112;0.00119)|OV - Ovarian serous cystadenocarcinoma(117;0.0141)|Lung(94;0.0183)|LUSC - Lung squamous cell carcinoma(192;0.0528)		GGCCCTGCTTCCCCTTTGGAA	0.358			NA											3	45					0	0	0.009096	0	0
TEP1	7011	broad.mit.edu	37	14	20876303	20876303	+	Missense_Mutation	SNP	G	G	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr14:20876303G>C	uc001vxe.2	-	2	336	c.296C>G	c.(295-297)TCT>TGT	p.S99C	TEP1_uc010tlf.1_RNA|TEP1_uc010tlg.1_Missense_Mutation_p.S99C	NM_007110	NP_009041	Q99973	TEP1_HUMAN	telomerase-associated protein 1	99	TEP1 N-terminal 4.				telomere maintenance via recombination	chromosome, telomeric region|cytoplasm|nuclear matrix|soluble fraction|telomerase holoenzyme complex	ATP binding|RNA binding			ovary(5)	5	all_cancers(95;0.00123)	all_lung(585;0.235)	Epithelial(56;7.42e-08)|all cancers(55;6.46e-07)	GBM - Glioblastoma multiforme(265;0.028)|READ - Rectum adenocarcinoma(17;0.233)		TGGGTGGGCAGAAACATGTCC	0.552			NA											5	122					0	0	0.000602	0	0
PLEKHG3	26030	broad.mit.edu	37	14	65208308	65208308	+	Silent	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr14:65208308A>G	uc001xho.1	+	16	2342	c.2073A>G	c.(2071-2073)CCA>CCG	p.P691P	PLEKHG3_uc001xhn.1_Silent_p.P635P|PLEKHG3_uc001xhp.2_Silent_p.P812P|PLEKHG3_uc010aqh.1_Silent_p.P233P|PLEKHG3_uc001xhq.1_Silent_p.P196P	NM_015549	NP_056364	A1L390	PKHG3_HUMAN	pleckstrin homology domain containing, family G,	691					regulation of Rho protein signal transduction	intracellular	Rho guanyl-nucleotide exchange factor activity			skin(1)	1				all cancers(60;0.00802)|OV - Ovarian serous cystadenocarcinoma(108;0.0109)|BRCA - Breast invasive adenocarcinoma(234;0.0485)		CCCCAAGCCCAGGCTGCCCAG	0.577			NA											3	58					0	0	0.000602	0	0
ADAM21P1	145241	broad.mit.edu	37	14	70713834	70713834	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr14:70713834G>A	uc010ttg.1	-	1	685	c.34C>T	c.(34-36)CGC>TGC	p.R12C		NR_003951				SubName: Full=ADAM21-like protein;												0						AACTGTTGGCGTGCTACTTCC	0.453			NA											6	60					0	0	0.001168	0	0
CDCA4	55038	broad.mit.edu	37	14	105477868	105477868	+	Silent	SNP	G	G	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr14:105477868G>C	uc001yqa.2	-	2	495	c.399C>G	c.(397-399)ACC>ACG	p.T133T	CDCA4_uc001yqb.2_Silent_p.T133T	NM_145701	NP_663747	Q9BXL8	CDCA4_HUMAN	cell division cycle associated 4	133						nucleus				ovary(1)	1		all_cancers(154;0.0798)|Melanoma(154;0.155)|all_epithelial(191;0.183)	OV - Ovarian serous cystadenocarcinoma(23;0.00778)|all cancers(16;0.00936)|Epithelial(46;0.0227)	Epithelial(152;0.142)		CCTGTGCTGAGGTGACTGGGC	0.592			NA											3	53					0	0	0.009096	0	0
TPSD1	23430	broad.mit.edu	37	16	1306674	1306674	+	Silent	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:1306674G>T	uc002clb.1	+	2	249	c.240G>T	c.(238-240)GCG>GCT	p.A80A	TPSD1_uc010brm.1_Silent_p.A18A	NM_012217	NP_036349	Q9BZJ3	TRYD_HUMAN	tryptase delta 1 precursor	80	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity				0		Hepatocellular(780;0.00369)				TAACCGCGGCGCACTGCGTGG	0.701			NA											7	55					7.48243e-07	9.3693e-07	0.006214	1	0
FAM86A	196483	broad.mit.edu	37	16	5140288	5140288	+	Missense_Mutation	SNP	C	C	T	rs144582297	byFrequency	TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:5140288C>T	uc002cyo.2	-	6	588	c.539G>A	c.(538-540)CGC>CAC	p.R180H	FAM86A_uc002cyp.2_Missense_Mutation_p.R146H	NM_201400	NP_958802	Q96G04	FA86A_HUMAN	hypothetical protein LOC196483 isoform 1	180											0						TGCCCGGGGGCGGCACATCTT	0.607			NA											12	51					0	0	0.013537	0	0
TAOK2	9344	broad.mit.edu	37	16	29994190	29994190	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:29994190G>T	uc002dva.1	+	11	1750	c.967G>T	c.(967-969)GGC>TGC	p.G323C	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|TAOK2_uc002dvb.1_Missense_Mutation_p.G323C|TAOK2_uc002dvc.1_Missense_Mutation_p.G323C|TAOK2_uc010bzm.1_Missense_Mutation_p.G323C|TAOK2_uc002dvd.1_Missense_Mutation_p.G150C	NM_016151	NP_057235	Q9UL54	TAOK2_HUMAN	TAO kinase 2 isoform 2	323					actin cytoskeleton organization|activation of MAPKK activity|apoptosis|cell migration|focal adhesion assembly|positive regulation of JNK cascade|protein targeting to membrane|regulation of cell growth|regulation of cell shape|response to stress	cytoplasmic vesicle membrane|cytoskeleton|dendrite|integral to membrane|nucleolus	ATP binding|protein serine/threonine kinase activity			ovary(1)	1						GGCACCCAACGGCCCTGGTGC	0.602			NA											15	69					8.34094e-07	1.03543e-06	0.008871	1	0
SLC6A10P	386757	broad.mit.edu	37	16	32890622	32890622	+	Missense_Mutation	SNP	T	T	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:32890622T>G	uc002edh.1	-	5	440	c.264A>C	c.(262-264)AAA>AAC	p.K88N	SLC6A10P_uc002edi.1_RNA					RecName: Full=Transporter;												0						CGTTGGTGTTTTTGTAGACCA	0.512			NA											3	32					0	0	0.000602	0	0
ZNF423	23090	broad.mit.edu	37	16	49669967	49669967	+	Silent	SNP	C	C	A	rs145829157		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:49669967C>A	uc002efs.2	-	5	3394	c.3096G>T	c.(3094-3096)ACG>ACT	p.T1032T	ZNF423_uc010vgn.1_Silent_p.T915T	NM_015069	NP_055884	Q2M1K9	ZN423_HUMAN	zinc finger protein 423	1032	C2H2-type 24.				cell differentiation|negative regulation of transcription, DNA-dependent|nervous system development|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	zinc ion binding			ovary(1)|lung(1)|kidney(1)|pancreas(1)	4		all_cancers(37;0.0155)				TGAGCTCAAGCGTGGAAGTGA	0.597			NA											4	35					4.096e-09	5.56438e-09	0.001168	1	0
TMEM208	29100	broad.mit.edu	37	16	67262440	67262440	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:67262440C>T	uc002esi.2	+	4	311	c.205C>T	c.(205-207)CAC>TAC	p.H69Y	LRRC29_uc002ese.2_5'Flank|LRRC29_uc002esf.2_5'Flank|LRRC29_uc002esg.2_5'Flank|LRRC29_uc010vjg.1_5'Flank|TMEM208_uc002esj.2_RNA	NM_014187	NP_054906	Q9BTX3	TM208_HUMAN	HSPC171 protein	69						integral to membrane					0		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.00067)|Epithelial(162;0.00442)|all cancers(182;0.0417)		GGCCAGCTACCACTCTATGAG	0.577			NA											6	15					0	0	0.001984	0	0
MYH8	4626	broad.mit.edu	37	17	10295215	10295215	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr17:10295215C>A	uc002gmm.2	-	39	5743	c.5648G>T	c.(5647-5649)AGA>ATA	p.R1883I	uc002gml.1_Intron	NM_002472	NP_002463	P13535	MYH8_HUMAN	myosin, heavy chain 8, skeletal muscle,	1883	Potential.				muscle filament sliding	cytosol|muscle myosin complex|myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|motor activity|structural constituent of muscle			skin(6)|ovary(3)|breast(2)	11						CTCAGCTTGTCTCTTGTATGA	0.378			NA							Trismus-Pseudocamptodactyly_Syndrome_with_Cardiac_Myxoma_and_Freckling				43	136					1.54886e-18	2.37272e-18	0.01441	1	0
MYOCD	93649	broad.mit.edu	37	17	12620700	12620700	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr17:12620700G>T	uc002gnn.2	+	4	514	c.215G>T	c.(214-216)TGC>TTC	p.C72F	MYOCD_uc002gno.2_Missense_Mutation_p.C72F|MYOCD_uc002gnp.1_5'Flank	NM_153604	NP_705832	Q8IZQ8	MYCD_HUMAN	myocardin isoform 2	72	RPEL 2.				cardiac muscle cell differentiation|negative regulation of cell proliferation|negative regulation of cyclin-dependent protein kinase activity|positive regulation of smooth muscle cell differentiation|positive regulation of smooth muscle contraction|positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|regulation of histone acetylation|smooth muscle cell differentiation	nucleus	nucleic acid binding|RNA polymerase II transcription factor binding transcription factor activity|transcription factor binding			central_nervous_system(2)|skin(2)|ovary(1)	5				UCEC - Uterine corpus endometrioid carcinoma (92;0.0969)		AGAAACAGGTGCAACAGTGCC	0.428			NA											6	29					3.09899e-07	3.94915e-07	0.004482	1	0
RNF213	57674	broad.mit.edu	37	17	78319618	78319618	+	Missense_Mutation	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr17:78319618A>G	uc002jyh.1	+	4	1925	c.1702A>G	c.(1702-1704)ATA>GTA	p.I568V		NM_020914	NP_065965	Q9HCF4	ALO17_HUMAN	ring finger protein 213	Error:Variant_position_missing_in_Q9HCF4_after_alignment								p.I568L(1)		ovary(8)|lung(6)|breast(3)|large_intestine(2)|central_nervous_system(1)|pancreas(1)	21	all_neural(118;0.0538)		BRCA - Breast invasive adenocarcinoma(99;0.0252)|OV - Ovarian serous cystadenocarcinoma(97;0.057)			AACGGAAGCTATAAGCTGTAT	0.488			NA											16	84					0	0	0.007413	0	0
SMAD4	4089	broad.mit.edu	37	18	48593406	48593406	+	Missense_Mutation	SNP	G	G	T	rs121912580		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr18:48593406G>T	uc010xdp.1	+	10	1695	c.1157G>T	c.(1156-1158)GGT>GTT	p.G386V	SMAD4_uc002lfb.3_Missense_Mutation_p.G231V	NM_005359	NP_005350	Q13485	SMAD4_HUMAN	mothers against decapentaplegic homolog 4	386	MH2.				BMP signaling pathway|negative regulation of cell growth|negative regulation of protein catabolic process|negative regulation of transcription, DNA-dependent|palate development|positive regulation of epithelial to mesenchymal transition|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of SMAD protein import into nucleus|positive regulation of transforming growth factor beta receptor signaling pathway|regulation of transforming growth factor-beta2 production|response to hypoxia|response to transforming growth factor beta stimulus|SMAD protein complex assembly|SMAD protein signal transduction|transforming growth factor beta receptor signaling pathway	activin responsive factor complex|centrosome|cytosol	I-SMAD binding|protein homodimerization activity|R-SMAD binding|transcription regulatory region DNA binding|transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	p.0?(35)|p.G386R(5)|p.?(2)|p.G386C(1)		pancreas(170)|large_intestine(108)|thyroid(19)|lung(11)|small_intestine(9)|upper_aerodigestive_tract(8)|biliary_tract(8)|ovary(7)|breast(6)|stomach(5)|oesophagus(3)|testis(2)|central_nervous_system(2)|haematopoietic_and_lymphoid_tissue(2)|gastrointestinal_tract_(site_indeterminate)(2)|liver(2)|kidney(1)|urinary_tract(1)|vulva(1)|skin(1)|NS(1)	369		all_cancers(7;0.203)|Colorectal(6;0.003)|all_epithelial(6;0.00336)		Colorectal(16;0.0032)|COAD - Colon adenocarcinoma(17;0.0708)|READ - Rectum adenocarcinoma(32;0.155)		ATAGGCAAAGGTGTGCAGTTG	0.368			NA							Juvenile_Polyposis|Hereditary_Hemorrhagic_Telangiectasia				18	68					1.55469e-16	2.33204e-16	0.00333	1	0
TIMM44	10469	broad.mit.edu	37	19	8002966	8002966	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:8002966G>A	uc002miz.2	-	3	260	c.258C>T	c.(256-258)GAC>GAT	p.D86D	TIMM44_uc002mja.2_Translation_Start_Site|TIMM44_uc010dvx.1_RNA	NM_006351	NP_006342	O43615	TIM44_HUMAN	translocase of inner mitochondrial membrane 44	86					protein targeting to mitochondrion	mitochondrial inner membrane presequence translocase complex|mitochondrial matrix	ATP binding|P-P-bond-hydrolysis-driven protein transmembrane transporter activity			ovary(1)	1						TTCTGGCCTCGTCACGGAATT	0.373			NA											7	174					0	0	0.00308	0	0
CYP2A6	1548	broad.mit.edu	37	19	41349784	41349784	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:41349784G>T	uc002opl.3	-	9	1423	c.1402C>A	c.(1402-1404)CCT>ACT	p.P468T		NM_000762	NP_000753	P11509	CP2A6_HUMAN	cytochrome P450, family 2, subfamily A,	468					coumarin catabolic process|exogenous drug catabolic process|steroid metabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|microsome	aromatase activity|coumarin 7-hydroxylase activity|electron carrier activity|enzyme binding|heme binding			ovary(2)	2			LUSC - Lung squamous cell carcinoma(20;0.000219)|Lung(22;0.000959)		Chlorzoxazone(DB00356)|Diethylstilbestrol(DB00255)|Estradiol(DB00783)|Ethinyl Estradiol(DB00977)|Formoterol(DB00983)|Halothane(DB01159)|Letrozole(DB01006)|Methoxsalen(DB00553)|Metyrapone(DB01011)|Nicotine(DB00184)|Pilocarpine(DB01085)|Tolbutamide(DB01124)|Tranylcypromine(DB00752)	ATGTCCTTAGGTGACTGGGAG	0.572			NA											8	88					2.68362e-12	3.98393e-12	0.013537	1	0
TEX101	83639	broad.mit.edu	37	19	43920682	43920682	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:43920682G>T	uc010xwo.1	+	4	561	c.366G>T	c.(364-366)CAG>CAT	p.Q122H	TEX101_uc002owk.2_Missense_Mutation_p.Q140H	NM_001130011	NP_001123483	Q9BY14	TX101_HUMAN	testis expressed 101 isoform 2	122						anchored to membrane|plasma membrane				ovary(1)	1		Prostate(69;0.0199)				GCCTGTCTCAGTTTTGGGAGT	0.483			NA											39	181					2.54354e-34	4.06966e-34	0.009718	1	0
SYMPK	8189	broad.mit.edu	37	19	46319250	46319250	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:46319250C>A	uc002pdn.2	-	26	3791	c.3546G>T	c.(3544-3546)CCG>CCT	p.P1182P	RSPH6A_uc002pdm.2_5'Flank	NM_004819	NP_004810	Q92797	SYMPK_HUMAN	symplekin	1182					cell adhesion|mRNA processing	cytoplasm|cytoskeleton|nucleoplasm|tight junction	protein binding			ovary(1)	1		all_neural(266;0.0299)|Ovarian(192;0.0308)		OV - Ovarian serous cystadenocarcinoma(262;0.00509)|GBM - Glioblastoma multiforme(486;0.0593)		CAGACGGGGGCGGGCCTGGCC	0.587			NA											4	15					2.0095e-06	2.43166e-06	0.001984	1	0
CRX	1406	broad.mit.edu	37	19	48342874	48342874	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:48342874C>A	uc002phq.3	+	4	754	c.550C>A	c.(550-552)CCG>ACG	p.P184T		NM_000554	NP_000545	O43186	CRX_HUMAN	cone-rod homeobox protein	184					organ morphogenesis|response to stimulus|visual perception		leucine zipper domain binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(1)|central_nervous_system(1)	2		all_cancers(25;2.76e-09)|all_epithelial(76;7.01e-07)|all_lung(116;2.48e-06)|Lung NSC(112;5.15e-06)|Ovarian(192;0.0139)|all_neural(266;0.0146)|Breast(70;0.133)		OV - Ovarian serous cystadenocarcinoma(262;0.000266)|all cancers(93;0.000788)|Epithelial(262;0.0226)|GBM - Glioblastoma multiforme(486;0.0521)		GGCCTCAGGGCCGTCTCTGAC	0.672	Pancreas(57;461 1196 22201 40716 47188)		NA											6	34					1.06961e-07	1.40022e-07	0.00308	1	0
ZNF578	147660	broad.mit.edu	37	19	53014565	53014565	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:53014565G>A	uc002pzp.3	+	6	1175	c.931G>A	c.(931-933)GGT>AGT	p.G311S		NM_001099694	NP_001093164	Q96N58	ZN578_HUMAN	zinc finger protein 578	86					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0				GBM - Glioblastoma multiforme(134;0.00819)|OV - Ovarian serous cystadenocarcinoma(262;0.01)		ATGTCACACTGGTGAGAAACC	0.418			NA											3	96					0	0	0.004672	0	0
ZNF761	388561	broad.mit.edu	37	19	53958910	53958910	+	Silent	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:53958910A>G	uc010eqp.2	+	7	1607	c.1149A>G	c.(1147-1149)AAA>AAG	p.K383K	ZNF761_uc010ydy.1_Silent_p.K329K|ZNF761_uc002qbt.1_Silent_p.K329K	NM_001008401	NP_001008401	Q86XN6	ZN761_HUMAN	zinc finger protein 761	383	C2H2-type 7.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1				GBM - Glioblastoma multiforme(134;0.00786)		AACCCTACAAATGTAATGAGT	0.413			NA											5	273					0	0	0.001984	0	0
VN1R1	57191	broad.mit.edu	37	19	57967782	57967782	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr19:57967782C>T	uc002qos.1	-	1	73	c.73G>A	c.(73-75)GAT>AAT	p.D25N	ZNF547_uc002qpm.3_Intron	NM_020633	NP_065684	Q9GZP7	VN1R1_HUMAN	vomeronasal 1 receptor 1	25	Extracellular (Potential).				response to pheromone	integral to membrane|plasma membrane	pheromone receptor activity			ovary(1)	1		Colorectal(82;5.46e-05)|all_neural(62;0.0218)|Ovarian(87;0.0694)|Renal(1328;0.157)|Breast(46;0.222)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0254)|Lung(386;0.171)		TCTGAAGAATCAGTAGAATAA	0.343			NA											4	38					0	0	0.000602	0	0
APOB	338	broad.mit.edu	37	2	21234526	21234526	+	Silent	SNP	G	G	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:21234526G>C	uc002red.2	-	26	5342	c.5214C>G	c.(5212-5214)CTC>CTG	p.L1738L		NM_000384	NP_000375	P04114	APOB_HUMAN	apolipoprotein B precursor	1738					cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			ovary(11)|skin(9)|central_nervous_system(3)|large_intestine(2)|upper_aerodigestive_tract(1)|pancreas(1)	27	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)	TGTCATTTGAGAGCTTAAGTC	0.418			NA											6	243					0	0	0.001984	0	0
IFT172	26160	broad.mit.edu	37	2	27704107	27704107	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:27704107C>A	uc002rku.2	-	8	642	c.591G>T	c.(589-591)CCG>CCT	p.P197P	IFT172_uc002rkw.2_Silent_p.P197P|IFT172_uc010yls.1_Silent_p.P176P|IFT172_uc010ezc.2_Silent_p.P197P|IFT172_uc002rkv.2_Silent_p.P197P	NM_015662	NP_056477	Q9UG01	IF172_HUMAN	selective LIM binding factor homolog	197	WD 5.				cilium assembly	cilium	binding			large_intestine(1)|ovary(1)	2	Acute lymphoblastic leukemia(172;0.155)					AGGGTGGACACGGGTGGTTAA	0.483			NA											5	27					1.06961e-07	1.40022e-07	0.00308	1	0
SRBD1	55133	broad.mit.edu	37	2	45774718	45774718	+	Missense_Mutation	SNP	T	T	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:45774718T>A	uc002rus.2	-	13	1785	c.1709A>T	c.(1708-1710)CAT>CTT	p.H570L	SRBD1_uc010yoc.1_Missense_Mutation_p.H89L	NM_018079	NP_060549	Q8N5C6	SRBD1_HUMAN	S1 RNA binding domain 1	570					nucleobase, nucleoside, nucleotide and nucleic acid metabolic process		hydrolase activity, acting on ester bonds|RNA binding			central_nervous_system(1)	1		all_hematologic(82;0.166)|Acute lymphoblastic leukemia(82;0.17)	LUSC - Lung squamous cell carcinoma(58;0.0917)|Lung(47;0.154)			TTGTCCACAATGCAAGTAAAC	0.323			NA											7	36					0	0	0.010729	0	0
SRBD1	55133	broad.mit.edu	37	2	45774723	45774723	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:45774723G>A	uc002rus.2	-	13	1780	c.1704C>T	c.(1702-1704)TAC>TAT	p.Y568Y	SRBD1_uc010yoc.1_Silent_p.Y87Y	NM_018079	NP_060549	Q8N5C6	SRBD1_HUMAN	S1 RNA binding domain 1	568					nucleobase, nucleoside, nucleotide and nucleic acid metabolic process		hydrolase activity, acting on ester bonds|RNA binding			central_nervous_system(1)	1		all_hematologic(82;0.166)|Acute lymphoblastic leukemia(82;0.17)	LUSC - Lung squamous cell carcinoma(58;0.0917)|Lung(47;0.154)			CACAATGCAAGTAAACCACAT	0.313			NA											7	33					0	0	0.010729	0	0
ANTXR1	84168	broad.mit.edu	37	2	69330019	69330019	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:69330019G>A	uc002sfg.2	+	10	1105	c.749G>A	c.(748-750)CGC>CAC	p.R250H	ANTXR1_uc002sfe.2_Missense_Mutation_p.R250H|ANTXR1_uc002sff.2_Missense_Mutation_p.R250H|ANTXR1_uc002sfd.2_Missense_Mutation_p.R250H|hsa-mir-3126|MI0014143_5'Flank	NM_032208	NP_115584	Q9H6X2	ANTR1_HUMAN	anthrax toxin receptor 1 isoform 1 precursor	250	Extracellular (Potential).				actin cytoskeleton reorganization|substrate adhesion-dependent cell spreading	filopodium membrane|integral to membrane|lamellipodium membrane	actin filament binding|collagen binding|metal ion binding|protein binding|transmembrane receptor activity			ovary(2)|skin(2)	4						CGACATGCCCGCAACGTGGAC	0.478			NA							Familial_Infantile_Hemangioma				6	239					0	0	0.001984	0	0
MRPL53	116540	broad.mit.edu	37	2	74699360	74699360	+	Silent	SNP	A	A	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:74699360A>T	uc002sln.2	-	3	365	c.225T>A	c.(223-225)ATT>ATA	p.I75I	CCDC142_uc002slo.2_RNA	NM_053050	NP_444278	Q96EL3	RM53_HUMAN	mitochondrial ribosomal protein L53 precursor	75						mitochondrion|ribosome					0						CGCCGCGCATAATCAGGCGAT	0.682			NA											5	24					0	0	0.000602	0	0
MRPS5	64969	broad.mit.edu	37	2	95766248	95766248	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:95766248G>A	uc002sub.2	-	10	1120	c.902C>T	c.(901-903)ACG>ATG	p.T301M	MRPS5_uc002suc.2_RNA	NM_031902	NP_114108	P82675	RT05_HUMAN	mitochondrial ribosomal protein S5	301					translation	mitochondrion|ribosome	protein binding|RNA binding|structural constituent of ribosome			ovary(2)|central_nervous_system(1)	3						CTTGATATGCGTCCTTTTAAA	0.328			NA											3	46					0	0	0.004672	0	0
SCN1A	6323	broad.mit.edu	37	2	166900521	166900521	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:166900521C>T	uc010zcz.1	-	11	1719	c.1701G>A	c.(1699-1701)AGG>AGA	p.R567R	SCN1A_uc002udo.3_Silent_p.R436R|SCN1A_uc010fpk.2_Silent_p.R436R	NM_006920	NP_008851	P35498	SCN1A_HUMAN	sodium channel, voltage-gated, type I, alpha	567						voltage-gated sodium channel complex	voltage-gated sodium channel activity			ovary(6)|skin(6)|large_intestine(1)	13					Lamotrigine(DB00555)|Levetiracetam(DB01202)|Phenacemide(DB01121)|Phenytoin(DB00252)|Topiramate(DB00273)|Zonisamide(DB00909)	TGCTATTTCGCCTTGGTGAAA	0.418			NA											12	48					0	0	0.004007	0	0
HAT1	8520	broad.mit.edu	37	2	172809485	172809485	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:172809485C>T	uc002uhi.2	+	4	351	c.275C>T	c.(274-276)GCA>GTA	p.A92V	HAT1_uc010fqi.2_Intron|HAT1_uc002uhj.2_Missense_Mutation_p.A7V	NM_003642	NP_003633	O14929	HAT1_HUMAN	histone acetyltransferase 1	92					chromatin silencing at telomere|DNA packaging	cytoplasm|nuclear matrix|nucleoplasm	histone acetyltransferase activity|protein binding			large_intestine(1)|ovary(1)	2			OV - Ovarian serous cystadenocarcinoma(117;0.216)			GTTGAATATGCATCTAAAGTT	0.303			NA											4	79					0	0	0.000602	0	0
NFE2L2	4780	broad.mit.edu	37	2	178098809	178098809	+	Missense_Mutation	SNP	T	T	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:178098809T>A	uc002ulh.3	-	2	791	c.236A>T	c.(235-237)GAG>GTG	p.E79V	NFE2L2_uc002ulg.3_Missense_Mutation_p.E63V|NFE2L2_uc010zfa.1_Missense_Mutation_p.E63V|NFE2L2_uc002uli.3_Missense_Mutation_p.E63V|NFE2L2_uc010fra.2_Missense_Mutation_p.E63V|NFE2L2_uc010frb.2_Missense_Mutation_p.E63V	NM_006164	NP_006155	Q16236	NF2L2_HUMAN	nuclear factor erythroid 2-like 2 isoform 1	79					transcription from RNA polymerase II promoter	centrosome|cytosol|nucleus|plasma membrane	protein dimerization activity|protein domain specific binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)	1			Epithelial(96;0.00442)|OV - Ovarian serous cystadenocarcinoma(117;0.00739)|all cancers(119;0.0195)|LUSC - Lung squamous cell carcinoma(2;0.036)|Lung(16;0.0935)			TTCACCTGTCTCTTCATCTAG	0.438			NA	Mis		NSCLC|HNSCC					HNSCC(56;0.16)			11	50					0	0	0.00245	0	0
TTN	7273	broad.mit.edu	37	2	179456035	179456035	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:179456035C>T	uc010zfg.1	-	253	52937	c.52713G>A	c.(52711-52713)AAG>AAA	p.K17571K	uc002umo.2_RNA|uc002ump.1_Intron|TTN_uc010zfh.1_Silent_p.K11266K|TTN_uc010zfi.1_Silent_p.K11199K|TTN_uc010zfj.1_Silent_p.K11074K	NM_133378	NP_596869	Q8WZ42	TITIN_HUMAN	titin isoform N2-A	18498							ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			ovary(58)|stomach(19)|large_intestine(17)|lung(16)|skin(16)|breast(10)|pancreas(7)|kidney(4)|central_nervous_system(3)|urinary_tract(2)|upper_aerodigestive_tract(1)	153			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			TTAAGCAGTTCTTAATGGTAA	0.433			NA											13	402					0	0	0.001855	0	0
FN1	2335	broad.mit.edu	37	2	216296671	216296671	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:216296671C>A	uc002vfa.2	-	4	698	c.432G>T	c.(430-432)GGG>GGT	p.G144G	FN1_uc002vfb.2_Silent_p.G144G|FN1_uc002vfc.2_Silent_p.G144G|FN1_uc002vfd.2_Silent_p.G144G|FN1_uc002vfe.2_Silent_p.G144G|FN1_uc002vff.2_Silent_p.G144G|FN1_uc002vfg.2_Silent_p.G144G|FN1_uc002vfh.2_Silent_p.G144G|FN1_uc002vfi.2_Silent_p.G144G|FN1_uc002vfj.2_Silent_p.G144G|FN1_uc002vfl.2_Silent_p.G144G	NM_212482	NP_997647	P02751	FINC_HUMAN	fibronectin 1 isoform 1 preproprotein	144	Fibrin- and heparin-binding 1.|Fibronectin type-I 3.				acute-phase response|angiogenesis|leukocyte migration|peptide cross-linking|platelet activation|platelet degranulation|regulation of cell shape|substrate adhesion-dependent cell spreading	ER-Golgi intermediate compartment|fibrinogen complex|platelet alpha granule lumen|proteinaceous extracellular matrix	collagen binding|extracellular matrix structural constituent|heparin binding			central_nervous_system(7)|large_intestine(2)|breast(2)|ovary(1)|pancreas(1)	13		Renal(323;0.127)		Epithelial(149;9.59e-07)|all cancers(144;0.000174)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00948)	Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	AGGACTGACCCCCTTCATGGC	0.448			NA											19	86					1.50039e-11	2.18239e-11	0.012319	1	0
SPHKAP	80309	broad.mit.edu	37	2	228856017	228856017	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr2:228856017G>A	uc002vpq.2	-	10	4794	c.4747C>T	c.(4747-4749)CTT>TTT	p.L1583F	SPHKAP_uc002vpp.2_Missense_Mutation_p.L1554F|SPHKAP_uc010zlx.1_Intron	NM_001142644	NP_001136116	Q2M3C7	SPKAP_HUMAN	sphingosine kinase type 1-interacting protein	1583						cytoplasm	protein binding			skin(5)|ovary(4)|lung(1)	10		Renal(207;0.025)|all_hematologic(139;0.15)|all_lung(227;0.204)|Acute lymphoblastic leukemia(138;0.205)|Esophageal squamous(248;0.23)		Epithelial(121;8.17e-11)|all cancers(144;7.92e-08)|Lung(261;0.0168)|LUSC - Lung squamous cell carcinoma(224;0.0232)		TGTCCTTTAAGAATCTTCTTT	0.413			NA											8	84					0	0	0.004482	0	0
ADAM33	80332	broad.mit.edu	37	20	3651739	3651739	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr20:3651739G>A	uc002wit.2	-	19	2241	c.2154C>T	c.(2152-2154)GCC>GCT	p.A718A	ADAM33_uc002wiq.1_5'Flank|ADAM33_uc002wir.1_Silent_p.A718A|ADAM33_uc002wis.2_Silent_p.A214A|ADAM33_uc002wiu.2_Silent_p.A692A|uc002wiv.1_5'Flank|ADAM33_uc002wiw.1_RNA	NM_025220	NP_079496	Q9BZ11	ADA33_HUMAN	ADAM metallopeptidase domain 33 isoform alpha	718	Helical; (Potential).				proteolysis	integral to membrane	metalloendopeptidase activity|zinc ion binding			large_intestine(2)|ovary(1)|skin(1)	4						AGGCCAGGCCGGCCCCTGGGA	0.677			NA											3	7					0	0	0.004672	0	0
C20orf26	26074	broad.mit.edu	37	20	20172016	20172016	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr20:20172016G>A	uc002wru.2	+	15	1619	c.1543G>A	c.(1543-1545)GAA>AAA	p.E515K	C20orf26_uc010zse.1_Missense_Mutation_p.E495K	NM_015585	NP_056400	Q8NHU2	CT026_HUMAN	hypothetical protein LOC26074	515										ovary(3)|pancreas(1)	4				READ - Rectum adenocarcinoma(2;0.171)		ATTTGTAGCTGAAGTTGCAGA	0.343			NA											14	78					0	0	0.008871	0	0
C20orf132	140699	broad.mit.edu	37	20	35769666	35769666	+	Missense_Mutation	SNP	T	T	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr20:35769666T>C	uc010zvu.1	-	14	1508	c.1417A>G	c.(1417-1419)ACA>GCA	p.T473A	C20orf132_uc002xgk.2_Intron|C20orf132_uc002xgm.2_Missense_Mutation_p.T473A|C20orf132_uc002xgn.2_Missense_Mutation_p.T438A	NM_152503	NP_689716	Q9H579	CT132_HUMAN	hypothetical protein LOC140699 isoform 1	348											0		Myeloproliferative disorder(115;0.00878)				GTATCAAATGTAGTCATTATA	0.378			NA											4	5					0	0	0.000602	0	0
CDH4	1002	broad.mit.edu	37	20	60504878	60504878	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr20:60504878C>T	uc002ybn.1	+	13	2231	c.2217C>T	c.(2215-2217)CTC>CTT	p.L739L	CDH4_uc002ybp.1_Silent_p.L665L	NM_001794	NP_001785	P55283	CADH4_HUMAN	cadherin 4, type 1 preproprotein	739	Helical; (Potential).				adherens junction organization|cell junction assembly		calcium ion binding			lung(3)|ovary(2)|skin(1)	6			BRCA - Breast invasive adenocarcinoma(19;2.36e-08)			TGGCCATCCTCATCTGCATCC	0.622			NA											18	62					0	0	0.012319	0	0
MRAP	56246	broad.mit.edu	37	21	33684278	33684278	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr21:33684278G>A	uc002ypj.2	+	5	677	c.490G>A	c.(490-492)GGA>AGA	p.G164R	MRAP_uc002ypk.2_Intron|URB1_uc002ypn.2_3'UTR|MRAP_uc011ado.1_Missense_Mutation_p.G105R|MRAP_uc002ypl.2_Missense_Mutation_p.G164R	NM_178817	NP_848932	Q8TCY5	MRAP_HUMAN	melanocortin 2 receptor accessory protein	164	Extracellular (Potential).				positive regulation of cAMP biosynthetic process|protein localization at cell surface	endoplasmic reticulum|integral to membrane|perinuclear region of cytoplasm|plasma membrane	corticotropin hormone receptor binding|type 1 melanocortin receptor binding|type 3 melanocortin receptor binding|type 4 melanocortin receptor binding|type 5 melanocortin receptor binding				0						GCCTCCCCCTGGAGACAGGAC	0.582			NA											15	59					0	0	0.007413	0	0
SCN10A	6336	broad.mit.edu	37	3	38763897	38763897	+	Missense_Mutation	SNP	A	A	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:38763897A>T	uc003ciq.2	-	19	3359	c.3359T>A	c.(3358-3360)ATT>AAT	p.I1120N		NM_006514	NP_006505	Q9Y5Y9	SCNAA_HUMAN	sodium channel, voltage-gated, type X, alpha	1120					sensory perception	voltage-gated sodium channel complex				ovary(5)|skin(3)|large_intestine(1)|kidney(1)	10				KIRC - Kidney renal clear cell carcinoma(284;0.0769)|Kidney(284;0.0945)	Benzocaine(DB01086)|Bupivacaine(DB00297)|Chloroprocaine(DB01161)|Cocaine(DB00907)|Dibucaine(DB00527)|Dyclonine(DB00645)|Hexylcaine(DB00473)|Levobupivacaine(DB01002)|Lidocaine(DB00281)|Mepivacaine(DB00961)|Oxybuprocaine(DB00892)|Procaine(DB00721)|Proparacaine(DB00807)|Ropivacaine(DB00296)	ACAGTGGCGAATGCATCCTGT	0.562			NA											29	177					0	0	0.00623	0	0
LTF	4057	broad.mit.edu	37	3	46486797	46486797	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:46486797G>T	uc003cpq.2	-	12	1526	c.1488C>A	c.(1486-1488)TTC>TTA	p.F496L	LTF_uc003fzr.2_Missense_Mutation_p.F452L|LTF_uc010hjh.2_Missense_Mutation_p.F494L|LTF_uc003cpr.2_Missense_Mutation_p.F483L	NM_002343	NP_002334	P02788	TRFL_HUMAN	lactotransferrin precursor	496	Transferrin-like 2.				cellular iron ion homeostasis|defense response to bacterium|humoral immune response|iron ion transport	extracellular region|stored secretory granule	ferric iron binding|heparin binding|protein binding|serine-type endopeptidase activity			central_nervous_system(2)|ovary(1)|lung(1)	4				all cancers(1;7.55e-14)|GBM - Glioblastoma multiforme(1;2.1e-09)|Epithelial(1;9.25e-07)|Colorectal(1;3.81e-05)|BRCA - Breast invasive adenocarcinoma(193;0.00129)|COAD - Colon adenocarcinoma(1;0.00308)|KIRC - Kidney renal clear cell carcinoma(197;0.0205)|Kidney(197;0.0242)|OV - Ovarian serous cystadenocarcinoma(275;0.089)	Pefloxacin(DB00487)	CCGTCTGGTTGAAGAGCAGGC	0.567			NA											6	96					0.000157383	0.000177056	0.00308	1	0
SETD2	29072	broad.mit.edu	37	3	47103738	47103738	+	Nonsense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:47103738G>A	uc003cqs.2	-	14	6261	c.6208C>T	c.(6208-6210)CAA>TAA	p.Q2070*	SETD2_uc003cqv.2_Nonsense_Mutation_p.Q2137*|SETD2_uc003cqt.1_RNA	NM_014159	NP_054878	Q9BYW2	SETD2_HUMAN	SET domain containing 2	2070					regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone-lysine N-methyltransferase activity|oxidoreductase activity|transition metal ion binding			kidney(24)|ovary(5)|skin(1)|central_nervous_system(1)|breast(1)	32		Acute lymphoblastic leukemia(5;0.0169)		BRCA - Breast invasive adenocarcinoma(193;0.000302)|KIRC - Kidney renal clear cell carcinoma(197;0.00732)|Kidney(197;0.00844)		TCTTTATTTTGAGTTTGCTTG	0.493			NA	N|F|S|Mis		clear cell renal carcinoma								29	168					0	0	0.010818	0	0
SETD2	29072	broad.mit.edu	37	3	47158197	47158197	+	Missense_Mutation	SNP	C	C	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:47158197C>G	uc003cqs.2	-	4	4555	c.4502G>C	c.(4501-4503)TGT>TCT	p.C1501S	SETD2_uc003cqv.2_Missense_Mutation_p.C1490S	NM_014159	NP_054878	Q9BYW2	SETD2_HUMAN	SET domain containing 2	1501	AWS.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone-lysine N-methyltransferase activity|oxidoreductase activity|transition metal ion binding			kidney(24)|ovary(5)|skin(1)|central_nervous_system(1)|breast(1)	32		Acute lymphoblastic leukemia(5;0.0169)		BRCA - Breast invasive adenocarcinoma(193;0.000302)|KIRC - Kidney renal clear cell carcinoma(197;0.00732)|Kidney(197;0.00844)		AAGAGGTGTACACTCACACTG	0.318			NA	N|F|S|Mis		clear cell renal carcinoma								16	71					0	0	0.00499	0	0
MAP4	4134	broad.mit.edu	37	3	47958225	47958225	+	Silent	SNP	T	T	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:47958225T>C	uc003csb.2	-	7	1618	c.1092A>G	c.(1090-1092)TTA>TTG	p.L364L	MAP4_uc003csc.3_Silent_p.L364L|MAP4_uc011bbf.1_Silent_p.L341L|MAP4_uc003csf.3_Silent_p.L381L	NM_002375	NP_002366	P27816	MAP4_HUMAN	microtubule-associated protein 4 isoform 1	364	26 residues 1.|17 X 14 AA tandem repeats.				negative regulation of microtubule depolymerization	cytoplasm|microtubule|microtubule associated complex	protein binding|structural molecule activity			ovary(2)|pancreas(1)	3				BRCA - Breast invasive adenocarcinoma(193;0.000721)|KIRC - Kidney renal clear cell carcinoma(197;0.00641)|Kidney(197;0.00736)		TGGAAGGGGCTAAGTCCATTT	0.478			NA											3	155					0	0	0.004672	0	0
HYAL3	8372	broad.mit.edu	37	3	50332964	50332964	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:50332964G>T	uc003czd.1	-	2	343	c.70C>A	c.(70-72)CCA>ACA	p.P24T	HYAL3_uc003czc.1_Missense_Mutation_p.P24T|HYAL3_uc003cze.1_Intron|HYAL3_uc003czf.1_Intron|HYAL3_uc003czg.1_Missense_Mutation_p.P24T	NM_003549	NP_003540	O43820	HYAL3_HUMAN	hyaluronoglucosaminidase 3 precursor	24					carbohydrate metabolic process	extracellular region|lysosome	hyalurononglucosaminidase activity			ovary(1)	1				BRCA - Breast invasive adenocarcinoma(193;0.000272)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00607)		GGGACCTGTGGTAGGGGCTGG	0.627			NA											9	40					0.000274275	0.000306168	0.004482	1	0
TEX264	51368	broad.mit.edu	37	3	51718507	51718507	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:51718507G>T	uc010hls.2	+	4	506	c.337G>T	c.(337-339)GAC>TAC	p.D113Y	TEX264_uc003dbk.3_Missense_Mutation_p.D113Y|TEX264_uc010hlt.2_5'UTR|TEX264_uc003dbl.3_Missense_Mutation_p.D113Y|TEX264_uc003dbm.3_Missense_Mutation_p.D152Y	NM_001129884	NP_001123356	Q9Y6I9	TX264_HUMAN	testis expressed 264 precursor	113						extracellular region					0				BRCA - Breast invasive adenocarcinoma(193;8.53e-05)|Kidney(197;0.000594)|KIRC - Kidney renal clear cell carcinoma(197;0.000759)		TGAGCTCATCGACCTCTACCA	0.582			NA											11	47					7.03913e-09	9.47322e-09	0.013537	1	0
CACNA2D3	55799	broad.mit.edu	37	3	54919551	54919551	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr3:54919551G>A	uc003dhf.2	+	23	2042	c.1994G>A	c.(1993-1995)CGC>CAC	p.R665H	CACNA2D3_uc011beu.1_RNA|CACNA2D3_uc003dhg.1_Missense_Mutation_p.R571H|CACNA2D3_uc003dhh.1_RNA|CACNA2D3_uc010hmv.1_Missense_Mutation_p.R399H|uc003dhk.1_Intron	NM_018398	NP_060868	Q8IZS8	CA2D3_HUMAN	calcium channel, voltage-dependent, alpha	665	Extracellular (Potential).					integral to membrane	calcium channel activity|metal ion binding|voltage-gated ion channel activity			large_intestine(3)|ovary(1)|breast(1)|central_nervous_system(1)|skin(1)	7				KIRC - Kidney renal clear cell carcinoma(284;0.00287)|Kidney(284;0.00327)		CCTGAGCACCGCCATCTGTCT	0.473			NA											7	25					0	0	0.008291	0	0
ZNF595	152687	broad.mit.edu	37	4	86669	86669	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:86669G>A	uc003fzv.1	+	6	1431	c.1275G>A	c.(1273-1275)ACG>ACA	p.T425T	ZNF595_uc003fzu.1_Intron|ZNF718_uc003fzt.3_Intron|ZNF595_uc011bus.1_Silent_p.T193T|ZNF595_uc011but.1_Silent_p.T193T	NM_182524	NP_872330	Q7Z3I0	Q7Z3I0_HUMAN	zinc finger protein 595	425					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding				0		all_cancers(4;0.0738)|all_epithelial(65;0.139)		Lung(54;0.0654)|Epithelial(2;0.0921)|all cancers(2;0.146)|LUSC - Lung squamous cell carcinoma(95;0.173)		AACCCTACACGTGCGAAGAAT	0.393			NA											3	39					0	0	0.004672	0	0
ZNF595	152687	broad.mit.edu	37	4	86672	86672	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:86672C>T	uc003fzv.1	+	6	1434	c.1278C>T	c.(1276-1278)TGC>TGT	p.C426C	ZNF595_uc003fzu.1_Intron|ZNF718_uc003fzt.3_Intron|ZNF595_uc011bus.1_Silent_p.C194C|ZNF595_uc011but.1_Silent_p.C194C	NM_182524	NP_872330	Q7Z3I0	Q7Z3I0_HUMAN	zinc finger protein 595	426					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding				0		all_cancers(4;0.0738)|all_epithelial(65;0.139)		Lung(54;0.0654)|Epithelial(2;0.0921)|all cancers(2;0.146)|LUSC - Lung squamous cell carcinoma(95;0.173)		CCTACACGTGCGAAGAATGTG	0.388			NA											3	42					0	0	0.004672	0	0
ZBTB49	166793	broad.mit.edu	37	4	4322915	4322915	+	Missense_Mutation	SNP	G	G	T	rs145779018		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:4322915G>T	uc003ghu.2	+	8	2345	c.2170G>T	c.(2170-2172)GGT>TGT	p.G724C	uc003ghw.2_5'Flank|ZBTB49_uc003ghv.2_Missense_Mutation_p.G207C|ZBTB49_uc010icy.2_RNA|ZBTB49_uc010icz.2_Missense_Mutation_p.G302C	NM_145291	NP_660334	Q6ZSB9	ZBT49_HUMAN	zinc finger protein 509	724					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)|skin(1)	2						CAACCACGGCGGTGACCCCCT	0.587			NA											6	35					0.00116845	0.00126508	0.001168	1	0
MOBKL1A	92597	broad.mit.edu	37	4	71824700	71824700	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:71824700C>T	uc003hfw.2	+	2	314	c.124C>T	c.(124-126)CGG>TGG	p.R42W	MOBKL1A_uc003hfv.1_Missense_Mutation_p.R42W|MOBKL1A_uc011cba.1_Missense_Mutation_p.R47W	NM_173468	NP_775739	Q7L9L4	MOL1A_HUMAN	MOB1, Mps One Binder kinase activator-like 1A	42					hippo signaling cascade|protein autophosphorylation	cytoplasm|nucleus	kinase activator activity|kinase binding|metal ion binding				0		all_hematologic(202;0.21)	Lung(101;0.235)			TGGCAACCTTCGGATGGCTGT	0.433			NA											10	28					0	0	0.013537	0	0
MFAP3L	9848	broad.mit.edu	37	4	170913125	170913125	+	Missense_Mutation	SNP	T	T	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:170913125T>A	uc003isp.3	-	3	812	c.634A>T	c.(634-636)ACC>TCC	p.T212S	MFAP3L_uc003isn.3_Missense_Mutation_p.T109S	NM_021647	NP_067679	O75121	MFA3L_HUMAN	microfibrillar-associated protein 3-like isoform	212	Cytoplasmic (Potential).					integral to membrane|plasma membrane				ovary(1)	1		Prostate(90;0.00601)|Renal(120;0.0183)|all_neural(102;0.122)|Melanoma(52;0.17)		GBM - Glioblastoma multiforme(119;0.0201)|LUSC - Lung squamous cell carcinoma(193;0.116)		TTGGCGGAGGTGATGATGGGG	0.532			NA											11	55					0	0	0.010729	0	0
VEGFC	7424	broad.mit.edu	37	4	177648996	177648996	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:177648996C>A	uc003ius.1	-	3	918	c.488G>T	c.(487-489)GGG>GTG	p.G163V		NM_005429	NP_005420	P49767	VEGFC_HUMAN	vascular endothelial growth factor C	163					angiogenesis|induction of positive chemotaxis|platelet activation|platelet degranulation|positive regulation of cell division|positive regulation of mast cell chemotaxis|substrate-dependent cell migration|vascular endothelial growth factor receptor signaling pathway	membrane|platelet alpha granule lumen	chemoattractant activity|growth factor activity			lung(5)	5		Breast(14;0.000223)|Renal(120;0.00988)|Prostate(90;0.00996)|Melanoma(52;0.0101)|all_hematologic(60;0.107)|all_neural(102;0.164)		all cancers(43;1.59e-18)|Epithelial(43;3.68e-16)|OV - Ovarian serous cystadenocarcinoma(60;8.52e-09)|GBM - Glioblastoma multiforme(59;0.000546)|STAD - Stomach adenocarcinoma(60;0.00308)|Colorectal(24;0.025)|COAD - Colon adenocarcinoma(29;0.0359)|LUSC - Lung squamous cell carcinoma(193;0.0397)		GCAGCAACCCCCACATCTGTA	0.547			NA											20	109					1.87028e-06	2.28238e-06	0.012319	1	0
SPEF2	79925	broad.mit.edu	37	5	35793372	35793372	+	Missense_Mutation	SNP	G	G	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:35793372G>C	uc003jjo.2	+	32	4777	c.4666G>C	c.(4666-4668)GAG>CAG	p.E1556Q	SPEF2_uc003jjp.1_Missense_Mutation_p.E1042Q|SPEF2_uc003jjr.2_Missense_Mutation_p.E611Q	NM_024867	NP_079143	Q9C093	SPEF2_HUMAN	KPL2 protein isoform 1	1556					nucleobase, nucleoside, nucleotide and nucleic acid metabolic process		ATP binding|nucleobase, nucleoside, nucleotide kinase activity|protein dimerization activity			skin(2)|ovary(1)|central_nervous_system(1)	4	all_lung(31;7.56e-05)		Lung(74;0.111)|COAD - Colon adenocarcinoma(61;0.14)|Colorectal(62;0.202)			GGAGCTCCTTGAGACCCTTCA	0.483			NA											13	77					0	0	0.003163	0	0
PRRC1	133619	broad.mit.edu	37	5	126874745	126874745	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:126874745G>A	uc003kuk.2	+	7	1115	c.935G>A	c.(934-936)CGG>CAG	p.R312Q	PRRC1_uc003kuj.3_Missense_Mutation_p.R312Q	NM_130809	NP_570721	Q96M27	PRRC1_HUMAN	proline-rich coiled-coil 1	312						Golgi apparatus					0		Prostate(80;0.165)	KIRC - Kidney renal clear cell carcinoma(527;0.0268)|Kidney(363;0.0488)	OV - Ovarian serous cystadenocarcinoma(64;0.0851)|Epithelial(69;0.113)		GCTCAGGAACGGATAGATAGC	0.373			NA											6	83					0	0	0.001984	0	0
AFF4	27125	broad.mit.edu	37	5	132232334	132232334	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:132232334G>A	uc003kyd.2	-	11	2396	c.1988C>T	c.(1987-1989)TCA>TTA	p.S663L	AFF4_uc011cxk.1_Missense_Mutation_p.S341L|AFF4_uc003kye.1_Missense_Mutation_p.S663L	NM_014423	NP_055238	Q9UHB7	AFF4_HUMAN	ALL1 fused gene from 5q31	663					transcription from RNA polymerase II promoter	mitochondrion|nucleolus	protein binding|sequence-specific DNA binding transcription factor activity			ovary(2)|kidney(2)|skin(1)	5		all_cancers(142;0.145)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)			AGGAGTTTGTGAGGAAGGAGG	0.428	Ovarian(126;889 1733 2942 10745 11605)		NA											17	66					0	0	0.010504	0	0
PCDHB3	56132	broad.mit.edu	37	5	140480999	140480999	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:140480999C>T	uc003lio.2	+	1	766	c.766C>T	c.(766-768)CCC>TCC	p.P256S	uc003lin.2_Intron	NM_018937	NP_061760	Q9Y5E6	PCDB3_HUMAN	protocadherin beta 3 precursor	256	Extracellular (Potential).|Cadherin 3.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to plasma membrane	calcium ion binding			ovary(1)|pancreas(1)	2			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			AGAGAATACCCCCGTTAACTC	0.428			NA											9	99					0	0	0.010729	0	0
PCDHB16	57717	broad.mit.edu	37	5	140563505	140563505	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:140563505C>A	uc003liv.2	+	1	2526	c.1371C>A	c.(1369-1371)ACC>ACA	p.T457T	PCDHB16_uc010jfw.1_Silent_p.T129T	NM_020957	NP_066008	Q9NRJ7	PCDBG_HUMAN	protocadherin beta 16 precursor	457	Extracellular (Potential).|Cadherin 5.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding			ovary(1)|pancreas(1)	2			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			CCTCCTACACCCTGTTCGTCC	0.567			NA											27	157					6.97489e-18	1.05725e-17	0.004878	1	0
PCDHB13	56123	broad.mit.edu	37	5	140594640	140594640	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:140594640C>A	uc003lja.1	+	1	1132	c.945C>A	c.(943-945)TCC>TCA	p.S315S		NM_018933	NP_061756	Q9Y5F0	PCDBD_HUMAN	protocadherin beta 13 precursor	315	Cadherin 3.|Extracellular (Potential).				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding			skin(2)|ovary(1)	3			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			AACTTCAGTCCTATGAAGTCA	0.388			NA											9	100					2.61681e-11	3.76821e-11	0.00245	1	0
FAT2	2196	broad.mit.edu	37	5	150920132	150920132	+	Nonsense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:150920132G>T	uc003lue.3	-	10	9048	c.9035C>A	c.(9034-9036)TCA>TAA	p.S3012*	GM2A_uc011dcs.1_Intron	NM_001447	NP_001438	Q9NYQ8	FAT2_HUMAN	FAT tumor suppressor 2 precursor	3012	Extracellular (Potential).|Cadherin 27.				epithelial cell migration|homophilic cell adhesion	cell-cell adherens junction|integral to membrane|nucleus	calcium ion binding			ovary(4)|upper_aerodigestive_tract(1)|skin(1)	6		Medulloblastoma(196;0.0912)|all_hematologic(541;0.104)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			TCTCACCTGTGAACACTGTGG	0.383			NA											4	26					0.00909568	0.00956042	0.009096	1	0
IL12B	3593	broad.mit.edu	37	5	158743806	158743806	+	Missense_Mutation	SNP	C	C	A	rs150030340		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:158743806C>A	uc003lxr.1	-	7	916	c.874G>T	c.(874-876)GAC>TAC	p.D292Y		NM_002187	NP_002178	P29460	IL12B_HUMAN	interleukin 12B precursor	292	Fibronectin type-III.				cell cycle arrest|cell migration|defense response to Gram-negative bacterium|interferon-gamma biosynthetic process|natural killer cell activation|negative regulation of interleukin-10 production|negative regulation of interleukin-17 production|negative regulation of smooth muscle cell proliferation|positive regulation of activated T cell proliferation|positive regulation of activation of JAK2 kinase activity|positive regulation of cell adhesion|positive regulation of defense response to virus by host|positive regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of interferon-gamma biosynthetic process|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-17 production|positive regulation of memory T cell differentiation|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|positive regulation of natural killer cell proliferation|positive regulation of NF-kappaB import into nucleus|positive regulation of NK T cell activation|positive regulation of NK T cell proliferation|positive regulation of osteoclast differentiation|positive regulation of smooth muscle cell apoptosis|positive regulation of T cell mediated cytotoxicity|positive regulation of T-helper 1 type immune response|positive regulation of T-helper 17 cell lineage commitment|positive regulation of T-helper 17 type immune response|positive regulation of tumor necrosis factor production|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|regulation of tyrosine phosphorylation of Stat1 protein|response to UV-B|sexual reproduction|T-helper 1 type immune response|T-helper cell differentiation	interleukin-12 complex|interleukin-23 complex|membrane	cytokine activity|cytokine receptor activity|interleukin-12 receptor binding|protein heterodimerization activity				0	Renal(175;0.00196)	Medulloblastoma(196;0.0354)|all_neural(177;0.138)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			GAGGTCTTGTCCGTGAAGACT	0.512			NA									OREG0016989	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	12	65					2.23348e-06	2.68018e-06	0.004007	1	0
HIST1H2BG	8339	broad.mit.edu	37	6	26216578	26216578	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr6:26216578G>A	uc003ngz.2	-	1	295	c.294C>T	c.(292-294)GCC>GCT	p.A98A	HIST1H2AE_uc003nha.1_5'Flank	NM_003518	NP_003509	P62807	H2B1C_HUMAN	histone cluster 1, H2bg	98					defense response to bacterium|nucleosome assembly	nucleosome|nucleus	DNA binding|protein binding			ovary(1)	1		all_hematologic(11;0.196)				GCAGACGCACGGCGGTCTGGA	0.572			NA											4	121					0	0	0.001168	0	0
C6orf221	154288	broad.mit.edu	37	6	74073285	74073285	+	Missense_Mutation	SNP	G	G	C			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr6:74073285G>C	uc003pgt.3	+	3	409	c.356G>C	c.(355-357)GGA>GCA	p.G119A		NM_001017361	NP_001017361	Q587J8	ECAT1_HUMAN	hypothetical protein LOC154288	119										skin(2)	2						CCAGGCTCAGGAAAGGCCCTC	0.617			NA											8	58					0	0	0.008291	0	0
FRK	2444	broad.mit.edu	37	6	116264242	116264242	+	Missense_Mutation	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr6:116264242A>G	uc003pwi.1	-	7	1694	c.1247T>C	c.(1246-1248)GTA>GCA	p.V416A		NM_002031	NP_002022	P42685	FRK_HUMAN	fyn-related kinase	416	Protein kinase.				negative regulation of cell proliferation	cytoplasm|nucleus	ATP binding|non-membrane spanning protein tyrosine kinase activity|protein binding			ovary(3)|lung(3)	6		all_cancers(87;0.00559)|all_epithelial(87;0.00738)|Colorectal(196;0.0465)		all cancers(137;0.0128)|OV - Ovarian serous cystadenocarcinoma(136;0.0209)|GBM - Glioblastoma multiforme(226;0.0459)|Epithelial(106;0.0625)		AAATGACCATACATCGGACTT	0.398			NA											5	55					0	0	0.001168	0	0
GRM1	2911	broad.mit.edu	37	6	146351216	146351216	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr6:146351216C>A	uc010khw.1	+	2	1033	c.563C>A	c.(562-564)ACA>AAA	p.T188K	GRM1_uc010khu.1_Missense_Mutation_p.T188K|GRM1_uc010khv.1_Missense_Mutation_p.T188K|GRM1_uc003qll.2_Missense_Mutation_p.T188K|GRM1_uc011edz.1_Missense_Mutation_p.T188K|GRM1_uc011eea.1_Missense_Mutation_p.T188K	NM_000838	NP_000829	Q13255	GRM1_HUMAN	glutamate receptor, metabotropic 1 isoform alpha	188	Extracellular (Potential).	Glutamate (By similarity).			synaptic transmission	integral to plasma membrane	G-protein coupled receptor activity|glutamate receptor activity			lung(8)|ovary(4)|central_nervous_system(3)|large_intestine(2)|breast(2)	19		Ovarian(120;0.0387)		OV - Ovarian serous cystadenocarcinoma(155;5.35e-08)|GBM - Glioblastoma multiforme(68;0.00762)	Acamprosate(DB00659)|L-Glutamic Acid(DB00142)	TATTCAGCCACAAGCATCGAC	0.522			NA											6	124					0.00307968	0.00328499	0.00308	1	0
KATNA1	11104	broad.mit.edu	37	6	149944338	149944338	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr6:149944338G>A	uc003qmr.1	-	3	447	c.402C>T	c.(400-402)GTC>GTT	p.V134V	KATNA1_uc003qms.2_Silent_p.V134V|KATNA1_uc003qmt.2_Silent_p.V134V|KATNA1_uc011eed.1_Silent_p.V134V	NM_007044	NP_008975	O75449	KTNA1_HUMAN	katanin p60 subunit A 1	134	Interaction with microtubule.				cell division|interphase of mitotic cell cycle|mitosis	microtubule|microtubule organizing center|spindle pole	ATP binding|microtubule binding|microtubule-severing ATPase activity|protein heterodimerization activity			skin(1)	1		Ovarian(120;0.0164)		OV - Ovarian serous cystadenocarcinoma(155;2.95e-12)|GBM - Glioblastoma multiforme(68;0.173)		GGTGAACTCTGACAGTTGTAC	0.423			NA											6	83					0	0	0.00308	0	0
BZW2	28969	broad.mit.edu	37	7	16744259	16744259	+	Missense_Mutation	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:16744259A>G	uc003stl.2	+	11	1374	c.1196A>G	c.(1195-1197)AAG>AGG	p.K399R	BZW2_uc003stm.2_Missense_Mutation_p.K205R|BZW2_uc003stj.2_Missense_Mutation_p.K399R|BZW2_uc003stk.2_Missense_Mutation_p.K323R|BZW2_uc003stp.2_Missense_Mutation_p.K247R|BZW2_uc010kua.2_Intron	NM_001159767	NP_001153239	Q9Y6E2	BZW2_HUMAN	basic leucine zipper and W2 domains 2	399	W2.				cell differentiation|nervous system development|RNA metabolic process		protein binding			ovary(2)	2	Lung NSC(10;0.0367)|all_lung(11;0.0837)			UCEC - Uterine corpus endometrioid carcinoma (126;0.199)		GACCAGATGAAGAAATTTGTT	0.328			NA											12	40					0	0	0.001855	0	0
FZD9	8326	broad.mit.edu	37	7	72849738	72849738	+	Silent	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:72849738C>A	uc003tyb.2	+	1	1630	c.1401C>A	c.(1399-1401)GTC>GTA	p.V467V		NM_003508	NP_003499	O00144	FZD9_HUMAN	frizzled 9 precursor	467	Helical; Name=6; (Potential).				B cell differentiation|brain development|canonical Wnt receptor signaling pathway|embryo development|gonad development|neuroblast proliferation|vasculature development	cell surface|filopodium membrane|integral to membrane|perinuclear region of cytoplasm	G-protein coupled receptor activity|PDZ domain binding|protein heterodimerization activity|protein homodimerization activity|Wnt receptor activity|Wnt-protein binding			central_nervous_system(1)	1		Lung NSC(55;0.0659)|all_lung(88;0.152)				TTTGCTATGTCTACGAACGCC	0.642	Pancreas(144;909 1878 36867 38226 39554)		NA											5	20					8.12818e-05	9.21621e-05	0.001984	1	0
TBL2	26608	broad.mit.edu	37	7	72988330	72988330	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:72988330G>A	uc003tyh.2	-	3	518	c.384C>T	c.(382-384)CGC>CGT	p.R128R	TBL2_uc011kex.1_Silent_p.R92R|TBL2_uc010lbg.2_Silent_p.R33R|TBL2_uc003tyi.2_5'UTR|TBL2_uc011key.1_5'UTR|TBL2_uc010lbh.2_Silent_p.R33R	NM_012453	NP_036585	Q9Y4P3	TBL2_HUMAN	transducin (beta)-like 2	128											0		Lung NSC(55;0.0659)|all_lung(88;0.152)				CTCTCATGCTGCGGTGCTCTC	0.602			NA											18	79					0	0	0.012319	0	0
SEMA3C	10512	broad.mit.edu	37	7	80374432	80374432	+	Silent	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:80374432G>A	uc003uhj.2	-	18	2596	c.2034C>T	c.(2032-2034)ACC>ACT	p.T678T	SEMA3C_uc011kgw.1_Silent_p.T696T	NM_006379	NP_006370	Q99985	SEM3C_HUMAN	semaphorin 3C precursor	678					immune response|response to drug	membrane	receptor activity			ovary(1)	1						AGCTGGCCCAGGTCCATGGGG	0.463			NA											16	63					0	0	0.00499	0	0
DYNC1I1	1780	broad.mit.edu	37	7	95625311	95625311	+	Nonsense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:95625311G>T	uc003uoc.3	+	10	1223	c.946G>T	c.(946-948)GAA>TAA	p.E316*	DYNC1I1_uc003uod.3_Nonsense_Mutation_p.E299*|DYNC1I1_uc003uob.2_Nonsense_Mutation_p.E279*|DYNC1I1_uc003uoe.3_Nonsense_Mutation_p.E296*|DYNC1I1_uc010lfl.2_Nonsense_Mutation_p.E305*	NM_004411	NP_004402	O14576	DC1I1_HUMAN	dynein, cytoplasmic 1, intermediate chain 1	316	WD 1.				vesicle transport along microtubule	condensed chromosome kinetochore|cytoplasmic dynein complex|microtubule|perinuclear region of cytoplasm|spindle pole|vesicle	microtubule binding|microtubule motor activity			ovary(3)|kidney(1)	4	all_cancers(62;9.39e-10)|all_epithelial(64;2.28e-09)|Lung NSC(181;0.165)|all_lung(186;0.191)		STAD - Stomach adenocarcinoma(171;0.0957)			TGCTCCCCATGAACCAGATGG	0.428			NA											8	131					0.00307968	0.00328499	0.00308	1	0
RELN	5649	broad.mit.edu	37	7	103138348	103138348	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:103138348C>T	uc003vca.2	-	55	9029	c.8869G>A	c.(8869-8871)GGT>AGT	p.G2957S	RELN_uc010liz.2_Missense_Mutation_p.G2957S	NM_005045	NP_005036	P78509	RELN_HUMAN	reelin isoform a	2957					axon guidance|cell adhesion|cerebral cortex tangential migration|glial cell differentiation|neuron migration|peptidyl-tyrosine phosphorylation|positive regulation of protein kinase activity|positive regulation of small GTPase mediated signal transduction|response to pain|spinal cord patterning	cytoplasm|dendrite|extracellular space|proteinaceous extracellular matrix	metal ion binding|protein serine/threonine/tyrosine kinase activity|serine-type peptidase activity			ovary(8)|upper_aerodigestive_tract(5)|large_intestine(2)|central_nervous_system(2)|skin(1)|pancreas(1)	19				COAD - Colon adenocarcinoma(1;8.98e-05)|Colorectal(1;0.00184)		TTCTCACTACCGATGCGCCCC	0.468	NSCLC(146;835 1944 15585 22231 52158)		NA											5	69					0	0	0.000602	0	0
PTK2B	2185	broad.mit.edu	37	8	27289812	27289812	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr8:27289812C>T	uc003xfn.1	+	15	1729	c.921C>T	c.(919-921)TCC>TCT	p.S307S	PTK2B_uc003xfo.1_Silent_p.S307S|PTK2B_uc003xfp.1_Silent_p.S307S|PTK2B_uc003xfq.1_Silent_p.S307S|PTK2B_uc010luq.1_Silent_p.S78S|PTK2B_uc003xfr.1_Silent_p.S53S	NM_173174	NP_775266	Q14289	FAK2_HUMAN	PTK2B protein tyrosine kinase 2 beta isoform a	307	FERM.				apoptosis|bone resorption|positive regulation of cell proliferation|signal complex assembly	cytosol	ATP binding|non-membrane spanning protein tyrosine kinase activity|signal transducer activity			lung(3)|ovary(1)|skin(1)	5		Ovarian(32;2.72e-05)		UCEC - Uterine corpus endometrioid carcinoma (27;0.023)|Epithelial(17;6.61e-10)|BRCA - Breast invasive adenocarcinoma(99;0.226)|Colorectal(74;0.229)		AGATCAGGTCCATCAGGTGCC	0.617			NA											5	46					0	0	0.006214	0	0
SCARA5	286133	broad.mit.edu	37	8	27823930	27823930	+	Splice_Site	SNP	C	C	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr8:27823930C>G	uc003xgj.2	-	3	681	c.241_splice	c.e3+1	p.V81_splice	SCARA5_uc010luz.2_Splice_Site_p.G81_splice|SCARA5_uc003xgk.2_Intron|SCARA5_uc003xgl.2_Splice_Site_p.V81_splice	NM_173833	NP_776194	Q6ZMJ2	SCAR5_HUMAN	scavenger receptor class A, member 5						cellular iron ion homeostasis|endocytosis|iron ion transmembrane transport|protein homotrimerization	integral to plasma membrane	ferritin receptor activity|scavenger receptor activity			central_nervous_system(1)|skin(1)	2		Ovarian(32;0.0218)		UCEC - Uterine corpus endometrioid carcinoma (27;0.023)|KIRC - Kidney renal clear cell carcinoma(542;0.152)|Kidney(114;0.181)|Colorectal(74;0.228)		CCTGCTCTTACCTGCTAAGAT	0.542			NA											11	36					0	0	0.010729	0	0
JAK2	3717	broad.mit.edu	37	9	5054630	5054630	+	Nonsense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr9:5054630C>T	uc010mhm.2	+	6	795	c.682C>T	c.(682-684)CGA>TGA	p.R228*	JAK2_uc003ziw.2_Nonsense_Mutation_p.R228*	NM_004972	NP_004963	O60674	JAK2_HUMAN	Janus kinase 2	228	Interaction with cytokine/interferon/growth hormone receptors (By similarity).|FERM.				actin filament polymerization|activation of caspase activity by protein phosphorylation|activation of JAK2 kinase activity|blood coagulation|cellular component movement|erythrocyte differentiation|interferon-gamma-mediated signaling pathway|interleukin-12-mediated signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|mammary gland epithelium development|mesoderm development|negative regulation of cell proliferation|negative regulation of DNA binding|positive regulation of apoptosis|positive regulation of cell-substrate adhesion|positive regulation of growth hormone receptor signaling pathway|positive regulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of phosphatidylinositol 3-kinase cascade|positive regulation of tumor necrosis factor production|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|protein autophosphorylation|regulation of inflammatory response|regulation of interferon-gamma-mediated signaling pathway|response to antibiotic|response to lipopolysaccharide|STAT protein import into nucleus|tumor necrosis factor-mediated signaling pathway|tyrosine phosphorylation of STAT protein	caveola|cytoskeleton|cytosol|endomembrane system|nucleus	ATP binding|growth hormone receptor binding|heme binding|histone binding|histone kinase activity (H3-Y41 specific)|interleukin-12 receptor binding|non-membrane spanning protein tyrosine kinase activity|protein kinase binding|SH2 domain binding		PCM1/JAK2(30)|PAX5/JAK2(18)|ETV6/JAK2(11)|BCR/JAK2(6)|SSBP2/JAK2(4)|SEC31A/JAK2(4)	haematopoietic_and_lymphoid_tissue(28629)|lung(5)|breast(5)|ovary(1)|liver(1)	28641	all_hematologic(13;0.137)	Acute lymphoblastic leukemia(23;0.0198)|Breast(48;0.147)		GBM - Glioblastoma multiforme(50;0.0237)|Lung(218;0.133)		GACAAGGAAGCGAATAAGGTA	0.348			1	T|Mis|O	ETV6|PCM1|BCR	ALL|AML|MPD| CML				Polycythemia_Vera_Familial				12	126					0	0	0.00245	0	0
KIAA1045	23349	broad.mit.edu	37	9	34976631	34976631	+	Missense_Mutation	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr9:34976631C>T	uc003zvq.2	+	5	921	c.743C>T	c.(742-744)GCG>GTG	p.A248V	KIAA1045_uc003zvr.2_Missense_Mutation_p.A248V	NM_015297	NP_056112	Q9UPV7	K1045_HUMAN	hypothetical protein LOC23349	248							calcium ion binding			skin(1)	1			LUSC - Lung squamous cell carcinoma(32;0.00575)			GAAGAGCAGGCGGCCCGCCAG	0.612			NA											4	69					0	0	0.001168	0	0
TMEM2	23670	broad.mit.edu	37	9	74360430	74360430	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr9:74360430G>T	uc011lsa.1	-	4	1078	c.538C>A	c.(538-540)CTG>ATG	p.L180M	TMEM2_uc010mos.2_Missense_Mutation_p.L180M|TMEM2_uc011lsb.1_RNA	NM_013390	NP_037522	Q9UHN6	TMEM2_HUMAN	transmembrane protein 2 isoform a	180	G8.					integral to membrane				ovary(2)	2		all_epithelial(88;4.56e-14)|Myeloproliferative disorder(762;0.0255)		GBM - Glioblastoma multiforme(74;7.45e-21)|OV - Ovarian serous cystadenocarcinoma(323;1.02e-16)		TCCTGGATCAGGATGTAATGA	0.438			NA											13	91					2.31682e-05	2.6905e-05	0.003163	1	0
ZNF510	22869	broad.mit.edu	37	9	99521573	99521573	+	Missense_Mutation	SNP	C	C	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr9:99521573C>G	uc004awn.1	-	6	1728	c.1539G>C	c.(1537-1539)GAG>GAC	p.E513D	ZNF510_uc004awo.1_Missense_Mutation_p.E513D	NM_014930	NP_055745	Q9Y2H8	ZN510_HUMAN	zinc finger protein 510	513					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Acute lymphoblastic leukemia(62;0.0527)				GAAAGGATTTCTCCCCTGTGT	0.408			NA											5	239					0	0	0.001168	0	0
BARHL1	56751	broad.mit.edu	37	9	135464783	135464783	+	Silent	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr9:135464783G>T	uc004cbp.1	+	3	1050	c.858G>T	c.(856-858)CCG>CCT	p.P286P		NM_020064	NP_064448	Q9BZE3	BARH1_HUMAN	BarH-like homeobox 1	286						nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0				OV - Ovarian serous cystadenocarcinoma(145;1.79e-06)|Epithelial(140;3.12e-05)		CCAGCGCGCCGCCGCCTGCTC	0.721			NA											4	34					0.000602214	0.000661976	0.000602	1	0
CACNA1B	774	broad.mit.edu	37	9	140953545	140953545	+	Silent	SNP	C	C	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr9:140953545C>T	uc004cog.2	+	30	4633	c.4488C>T	c.(4486-4488)CCC>CCT	p.P1496P	CACNA1B_uc011mfd.1_Silent_p.P1026P|CACNA1B_uc004coi.2_Silent_p.P710P	NM_000718	NP_000709	Q00975	CAC1B_HUMAN	calcium channel, voltage-dependent, N type,	1496	IV.|Extracellular (Potential).				membrane depolarization|synaptic transmission	voltage-gated calcium channel complex	ATP binding|protein C-terminus binding|voltage-gated calcium channel activity			breast(3)|large_intestine(2)|ovary(1)	6	all_cancers(76;0.166)			OV - Ovarian serous cystadenocarcinoma(145;1.16e-05)|Epithelial(140;0.000476)	Amlodipine(DB00381)|Gabapentin(DB00996)	ATGATGCACCCTATGAGTACG	0.542			NA											5	30					0	0	0.001984	0	0
SCML2	10389	broad.mit.edu	37	X	18275064	18275064	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:18275064G>A	uc004cyl.2	-	11	1517	c.1360C>T	c.(1360-1362)CAC>TAC	p.H454Y	SCML2_uc004cyk.3_RNA|SCML2_uc010nfd.1_Missense_Mutation_p.H454Y|SCML2_uc011miz.1_Missense_Mutation_p.H388Y|SCML2_uc010nfc.2_Missense_Mutation_p.H190Y	NM_006089	NP_006080	Q9UQR0	SCML2_HUMAN	sex comb on midleg-like 2	454					anatomical structure morphogenesis	PcG protein complex	DNA binding|sequence-specific DNA binding transcription factor activity				0	Hepatocellular(33;0.183)					TGCAGACTGTGGCAGAAGTTC	0.468	Esophageal Squamous(100;1252 1965 19021 35517)		NA											9	154					0	0	0.008291	0	0
FAM47B	170062	broad.mit.edu	37	X	34962077	34962077	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:34962077C>A	uc004ddi.1	+	1	1147	c.1129C>A	c.(1129-1131)CCT>ACT	p.P377T		NM_152631	NP_689844	Q8NA70	FA47B_HUMAN	hypothetical protein LOC170062	377										ovary(3)|breast(1)	4						ACTCACCAAGCCTGGTAAATA	0.537			NA											12	39					1.49906e-05	1.755e-05	0.00245	1	0
CACNA1F	778	broad.mit.edu	37	X	49066186	49066186	+	Missense_Mutation	SNP	G	G	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:49066186G>A	uc004dnb.2	-	41	4819	c.4757C>T	c.(4756-4758)ACA>ATA	p.T1586I	CACNA1F_uc010nip.2_Missense_Mutation_p.T1575I	NM_005183	NP_005174	O60840	CAC1F_HUMAN	calcium channel, voltage-dependent, L type,	1586	Cytoplasmic (Potential).				axon guidance|detection of light stimulus involved in visual perception	voltage-gated calcium channel complex	protein binding|voltage-gated calcium channel activity			breast(3)|ovary(1)|kidney(1)|skin(1)	6					Verapamil(DB00661)	GATCAGAAATGTGGCGTAGAA	0.592			NA											6	31					0	0	0.00308	0	0
AKAP4	8852	broad.mit.edu	37	X	49962221	49962221	+	Missense_Mutation	SNP	G	G	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:49962221G>T	uc004dow.1	-	3	272	c.148C>A	c.(148-150)CTG>ATG	p.L50M	AKAP4_uc004dov.1_Missense_Mutation_p.L41M|AKAP4_uc010njp.1_Translation_Start_Site|AKAP4_uc004dou.1_Missense_Mutation_p.L41M	NM_003886	NP_003877	Q5JQC9	AKAP4_HUMAN	A-kinase anchor protein 4 isoform 1	50					cell projection organization|single fertilization|sperm motility	cAMP-dependent protein kinase complex|cilium|cytoskeleton|microtubule-based flagellum	protein kinase A binding			kidney(3)|central_nervous_system(2)|ovary(1)|lung(1)|skin(1)	8	Ovarian(276;0.236)					TCTACATTCAGGGTGGACACA	0.378			NA											5	49					1.12685e-05	1.34105e-05	0.004482	1	0
RPS6KA6	27330	broad.mit.edu	37	X	83372087	83372087	+	Missense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:83372087C>A	uc004eej.1	-	11	1007	c.930G>T	c.(928-930)AGG>AGT	p.R310S	RPS6KA6_uc011mqt.1_Missense_Mutation_p.R310S|RPS6KA6_uc011mqu.1_Missense_Mutation_p.R207S	NM_014496	NP_055311	Q9UK32	KS6A6_HUMAN	ribosomal protein S6 kinase polypeptide 6	310	Protein kinase 1.				axon guidance|central nervous system development|intracellular protein kinase cascade|synaptic transmission	cytosol|nucleoplasm	ATP binding|magnesium ion binding|protein serine/threonine kinase activity			lung(5)|stomach(1)|central_nervous_system(1)|skin(1)	8						TTGCTGGATTCCTTTTGAATA	0.323			NA											13	34					1.3612e-06	1.67533e-06	0.003163	1	0
DOCK11	139818	broad.mit.edu	37	X	117707926	117707926	+	Nonsense_Mutation	SNP	C	C	A			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:117707926C>A	uc004eqp.2	+	12	1397	c.1334C>A	c.(1333-1335)TCA>TAA	p.S445*	DOCK11_uc004eqq.2_Nonsense_Mutation_p.S211*	NM_144658	NP_653259	Q5JSL3	DOC11_HUMAN	dedicator of cytokinesis 11	445					blood coagulation	cytosol	GTP binding			ovary(3)	3						AAGGGCTCTTCACCCGAATCT	0.468			NA											19	67					9.57634e-11	1.36534e-10	0.00333	1	0
GPR112	139378	broad.mit.edu	37	X	135430454	135430454	+	Missense_Mutation	SNP	A	A	G			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	A	A	-	-	A	A	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chrX:135430454A>G	uc004ezu.1	+	6	4880	c.4589A>G	c.(4588-4590)GAC>GGC	p.D1530G	GPR112_uc010nsb.1_Missense_Mutation_p.D1325G|GPR112_uc010nsc.1_Missense_Mutation_p.D1297G	NM_153834	NP_722576	Q8IZF6	GP112_HUMAN	G-protein coupled receptor 112	1530	Extracellular (Potential).				neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			ovary(5)|large_intestine(2)|skin(2)|lung(1)|breast(1)|pancreas(1)	12	Acute lymphoblastic leukemia(192;0.000127)					AAAGTTTCTGACACTCCCCCA	0.433			NA											3	102					0	0	0.000602	0	0
FBXO22	26263	broad.mit.edu	37	15	76225419	76225422	+	Frame_Shift_Del	DEL	CATA	CATA	-			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	CATA	CATA	-	-	CATA	CATA	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr15:76225419_76225422delCATA	uc002bbk.2	+	7	1293_1296	c.1188_1191delCATA	c.(1186-1191)CTCATAfs	p.L396fs	FBXO22_uc002bbl.2_Frame_Shift_Del_p.L292fs|FBXO22OS_uc002bbm.1_RNA	NM_147188	NP_671717	Q8NEZ5	FBX22_HUMAN	F-box only protein 22 isoform a	396_397					ubiquitin-dependent protein catabolic process		ubiquitin-protein ligase activity				0						TAATGGCACTCATACATCTGGGGT	0.343			NA											8	95	---	---	---	---	NA	NA	NA	NA	NA
LONP2	83752	broad.mit.edu	37	16	48382016	48382016	+	Frame_Shift_Del	DEL	G	G	-			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	G	G	-	-	G	G	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr16:48382016delG	uc002efi.1	+	14	2241	c.2152delG	c.(2152-2154)GGAfs	p.G718fs	LONP2_uc002efj.1_Frame_Shift_Del_p.G674fs	NM_031490	NP_113678	Q86WA8	LONP2_HUMAN	peroxisomal LON protease-like	718					misfolded or incompletely synthesized protein catabolic process|protein targeting to peroxisome|signal peptide processing	nucleoid|peroxisomal matrix	ATP binding|ATP-dependent peptidase activity|enzyme binding|sequence-specific DNA binding|serine-type endopeptidase activity				0						TAAAGCTTTTGGAAGTTTTGA	0.358			NA											11	70	---	---	---	---	NA	NA	NA	NA	NA
CLOCK	9575	broad.mit.edu	37	4	56316293	56316305	+	Frame_Shift_Del	DEL	CTTGAACTCCGAG	CTTGAACTCCGAG	-	rs148913372		TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	CTTGAACTCCGAG	CTTGAACTCCGAG	-	-	CTTGAACTCCGAG	CTTGAACTCCGAG	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:56316293_56316305delCTTGAACTCCGAG	uc003haz.1	-	17	2227_2239	c.1301_1313delCTCGGAGTTCAAG	c.(1300-1314)TCTCGGAGTTCAAGAfs	p.S434fs	CLOCK_uc003hba.1_Frame_Shift_Del_p.S434fs|CLOCK_uc010igu.1_5'Flank	NM_004898	NP_004889	O15516	CLOCK_HUMAN	clock	434_438					circadian rhythm|photoperiodism|positive regulation of transcription from RNA polymerase II promoter	cytoplasm|transcription factor complex	DNA binding|histone acetyltransferase activity|sequence-specific DNA binding transcription factor activity|signal transducer activity			central_nervous_system(2)|ovary(1)	3	Lung NSC(11;0.00335)|Glioma(25;0.08)|all_epithelial(27;0.0992)|all_neural(26;0.101)		LUSC - Lung squamous cell carcinoma(4;1.62e-07)|Lung(4;1.34e-06)|Epithelial(7;0.0107)			AGATGATTTTCTTGAACTCCGAGAAGAGGCAGA	0.432			NA											7	71	---	---	---	---	NA	NA	NA	NA	NA
FSTL5	56884	broad.mit.edu	37	4	162376268	162376268	+	Frame_Shift_Del	DEL	C	C	-			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr4:162376268delC	uc003iqh.2	-	15	2165	c.1729delG	c.(1729-1731)GCCfs	p.A577fs	FSTL5_uc003iqi.2_Frame_Shift_Del_p.A576fs|FSTL5_uc010iqv.2_Frame_Shift_Del_p.A567fs	NM_020116	NP_064501	Q8N475	FSTL5_HUMAN	follistatin-like 5 isoform a	577						extracellular region	calcium ion binding			ovary(2)|pancreas(2)|upper_aerodigestive_tract(1)|large_intestine(1)|central_nervous_system(1)|skin(1)	8	all_hematologic(180;0.24)			COAD - Colon adenocarcinoma(41;0.179)		TTCCCACTGGCCAGGGTAATT	0.398			NA											17	82	---	---	---	---	NA	NA	NA	NA	NA
LSM11	134353	broad.mit.edu	37	5	157171203	157171203	+	Frame_Shift_Del	DEL	C	C	-			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	C	C	-	-	C	C	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr5:157171203delC	uc003lxe.1	+	1	449	c.445delC	c.(445-447)CCCfs	p.P149fs		NM_173491	NP_775762	P83369	LSM11_HUMAN	LSM11, U7 small nuclear RNA associated	149					histone mRNA 3'-end processing|S phase of mitotic cell cycle|termination of RNA polymerase II transcription	histone pre-mRNA 3'end processing complex|nucleoplasm|U7 snRNP	protein binding|U7 snRNA binding				0	Renal(175;0.00488)	Medulloblastoma(196;0.0523)	Kidney(164;0.000171)|KIRC - Kidney renal clear cell carcinoma(164;0.000785)			CACGCGAATGCCCTGTGAGTC	0.761			NA											2	4	---	---	---	---	NA	NA	NA	NA	NA
SLC17A2	10246	broad.mit.edu	37	6	25921520	25921520	+	Frame_Shift_Del	DEL	T	T	-			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	T	T	-	-	T	T	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr6:25921520delT	uc011dkb.1	-	3	444	c.361delA	c.(361-363)ATGfs	p.M121fs	SLC17A2_uc011dkc.1_Frame_Shift_Del_p.M121fs|SLC17A2_uc003nfl.2_Frame_Shift_Del_p.M121fs			O00624	NPT3_HUMAN	SubName: Full=Solute carrier family 17 (Sodium phosphate), member 2, isoform CRA_b; SubName: Full=Putative uncharacterized protein SLC17A2;	121					phosphate metabolic process	integral to plasma membrane|membrane fraction	sodium:phosphate symporter activity			ovary(1)	1						GCACCAAGCATTTTTTTTGCT	0.453			NA											8	120	---	---	---	---	NA	NA	NA	NA	NA
TRA2A	29896	broad.mit.edu	37	7	23547133	23547135	+	In_Frame_Del	DEL	TTC	TTC	-			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	TTC	TTC	-	-	TTC	TTC	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:23547133_23547135delTTC	uc003swi.2	-	5	759_761	c.545_547delGAA	c.(544-549)GGAATG>GTG	p.182_183GM>V	TRA2A_uc011jzb.1_RNA|TRA2A_uc011jzc.1_In_Frame_Del_p.81_82GM>V|TRA2A_uc011jzd.1_In_Frame_Del_p.81_82GM>V	NM_013293	NP_037425	Q13595	TRA2A_HUMAN	transformer-2 alpha	182_183	RRM.				nuclear mRNA splicing, via spliceosome	nucleus	nucleotide binding|RNA binding			ovary(1)	1						TCCAGCTCCATTCCATTTGCCCT	0.404	Pancreas(121;2137 2973 46590)		NA											7	196	---	---	---	---	NA	NA	NA	NA	NA
GTF2IRD2P1	401375	broad.mit.edu	37	7	72664019	72664020	+	Translation_Start_Site	INS	-	-	T			TCGA-97-7941-01A-11D-2184-08	TCGA-97-7941-10A-01D-2184-08	-	-	-	-	-	-	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	61181eca-24b7-4256-bf0b-7902359e4f4b	eb7be5ed-361f-463a-aa9d-6408387ded3a	g.chr7:72664019_72664020insT	uc003txs.1	-	11	881_882	c.-47_-46insA	c.(-49--44)ATGCCC>ATGACCC		FKBP6_uc003twz.2_Intron	NR_002164				RecName: Full=General transcription factor II-I repeat domain-containing protein 2B; AltName: Full=GTF2I repeat domain-containing protein 2B; AltName: Full=Transcription factor GTF2IRD2-beta;												0						CACCCCCGGGGCATGCCATCAA	0.505			NA											2	4	---	---	---	---	NA	NA	NA	NA	NA