Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error AMPD1 270 genome.wustl.edu 36 1 115019836 115019836 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 115019836 115019836 A G SNP AMPD1 NM_000036 human genbank 54_36p -1 reviewed missense c.1517 p.I506T 1 HMMPfam_A_deaminase HMMPfam_A_deaminase;superfamily_Metallo-dependent hydrolases - no_errors MFN2 9927 genome.wustl.edu 36 1 11988549 11988549 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 11988549 11988549 C T SNP MFN2 NM_014874 human genbank 54_36p 1 reviewed missense c.1690 p.R564W 0.99 NULL - - no_errors DCST2 127579 genome.wustl.edu 36 1 153269192 153269192 + Missense_Mutation SNP A A C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A C A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 153269192 153269192 A C SNP DCST2 NM_144622 human genbank 54_36p -1 validated missense c.1169 p.I390S 1 NULL - - no_errors ARHGEF11 9826 genome.wustl.edu 36 1 155192962 155192962 + Silent SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 155192962 155192962 G A SNP ARHGEF11 NM_198236 human genbank 54_36p -1 reviewed silent c.1545 p.A515 1 NULL - - no_errors FCRL1 115350 genome.wustl.edu 36 1 156038510 156038510 + Silent SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 156038510 156038510 A G SNP FCRL1 NM_052938 human genbank 54_36p -1 provisional silent c.705 p.S235 0.52 NULL - - no_errors OR10X1 128367 genome.wustl.edu 36 1 156816153 156816153 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 156816153 156816153 G T SNP OR10X1 NM_001004477 human genbank 54_36p -1 provisional missense c.161 p.T54N 0.02 NULL - - no_errors LOC646347 646347 genome.wustl.edu 36 1 159132183 159132183 + RNA SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 159132183 159132183 C A SNP LOC646347 XR_017680 human genbank 54_36p 1 model rna NULL NULL 0.94 - - - pseudogene HMCN1 83872 genome.wustl.edu 36 1 184418038 184418038 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 184418038 184418038 C T SNP HMCN1 NM_031935 human genbank 54_36p 1 reviewed silent c.16410 p.C5470 1 NULL - - no_errors ASPM 259266 genome.wustl.edu 36 1 195337279 195337279 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 195337279 195337279 C T SNP ASPM NM_018136 human genbank 54_36p -1 validated silent c.7725 p.K2575 NULL IQ;HMMPfam_IQ;CH;HMMPfam_CH;Calponin-homology domain CH-domain;superfamily_Calponin-homology domain CH-domain;ARM repeat;superfamily_ARM repeat;P-loop containing nucleoside triphosphate hydrolases;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors RYR2 6262 genome.wustl.edu 36 1 235930157 235930157 + Missense_Mutation SNP T A T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T A T T T Unknown Valid Somatic Phase_III Capture 454_PCR_WGA dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 235930157 235930157 T A SNP RYR2 NM_001035 human genbank 54_36p 1 reviewed missense c.9134 p.V3045E 1 NULL HMMPfam_RYDR_ITPR;HMMPfam_efhand;HMMPfam_RyR;HMMPfam_MIR;HMMPfam_SPRY;HMMPfam_Ion_trans;HMMPfam_RR_TM4-6;HMMPfam_RIH_assoc;HMMPfam_Ins145_P3_rec;superfamily_EF-hand;superfamily_MIR domain (Pfam 02815) - no_errors SYTL1 84958 genome.wustl.edu 36 1 27549949 27549949 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 27549949 27549949 C A SNP SYTL1 NM_032872 human genbank 54_36p 1 provisional missense c.1047 p.N349K 1 NULL - - no_errors EYA3 2140 genome.wustl.edu 36 1 28234668 28234668 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 28234668 28234668 G T SNP EYA3 NM_001990 human genbank 54_36p -1 reviewed missense c.335 p.T112N 1 NULL - - no_errors SESN2 83667 genome.wustl.edu 36 1 28474027 28474027 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 28474027 28474027 C T SNP SESN2 NM_031459 human genbank 54_36p 1 reviewed silent c.1125 p.Y375 1 HMMPfam_PA26 HMMPfam_PA26,superfamily_AhpD-like - no_errors DNALI1 7802 genome.wustl.edu 36 1 37799838 37799838 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 37799838 37799838 A G SNP DNALI1 NM_003462 human genbank 54_36p 1 reviewed missense c.557 p.Y186C 1 NULL - - no_errors BSND 7809 genome.wustl.edu 36 1 55245270 55245270 + Silent SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 55245270 55245270 G A SNP BSND NM_057176 human genbank 54_36p 1 reviewed silent c.285 p.Q95 0.97 NULL - - no_errors FGGY 55277 genome.wustl.edu 36 1 60000837 60000837 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 60000837 60000837 A G SNP FGGY NM_018291 human genbank 54_36p 1 validated missense c.1313 p.D438G 0.02 NULL - - no_errors PTGFR 5737 genome.wustl.edu 36 1 78774697 78774697 + Nonsense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 78774697 78774697 G T SNP PTGFR NM_000959 human genbank 54_36p 1 reviewed nonsense c.817 p.G273* 1 NULL - - no_errors BCAR3 8412 genome.wustl.edu 36 1 93827462 93827462 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 1 93827462 93827462 G C SNP BCAR3 NM_003567 human genbank 54_36p -1 reviewed missense c.589 p.Q197E 1 NULL - - no_errors BLOC1S2 282991 genome.wustl.edu 36 10 102035928 102035928 + Missense_Mutation SNP T T C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 10 102035928 102035928 T C SNP BLOC1S2 NM_173809 human genbank 54_36p -1 validated missense c.88 p.K30E 0.82 NULL - - no_errors CUBN 8029 genome.wustl.edu 36 10 17022062 17022062 + Silent SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 10 17022062 17022062 C A SNP CUBN NM_001081 human genbank 54_36p -1 reviewed silent c.5523 p.T1841 HMMPfam_CUB HMMPfam_CUB;superfamily_Spermadhesin CUB domain;HMMPfam_EGF;HMMPfam_EGF_CA;superfamily_EGF/Laminin - no_errors CYP2C18 1562 genome.wustl.edu 36 10 96437584 96437584 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 10 96437584 96437584 G T SNP CYP2C18 NM_000772 human genbank 54_36p 1 reviewed missense c.236 p.G79V 0.87 HMMPfam_p450 HMMPfam_p450;superfamily_Cytochrome P450 - no_errors MMP7 4316 genome.wustl.edu 36 11 101906626 101906626 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 101906626 101906626 G T SNP MMP7 NM_002423 human genbank 54_36p -1 reviewed missense c.16 p.L6M 0.004 NULL "HMMPfam_Peptidase_M10,HMMPfam_PG_binding_1,superfamily_PGBD-like,superfamily_Metalloproteases (""zincins"") catalytic domain" - no_errors MMP8 4317 genome.wustl.edu 36 11 102098605 102098605 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 102098605 102098605 C T SNP MMP8 NM_002424 human genbank 54_36p -1 reviewed missense c.112 p.E38K 0.34 HMMPfam_PG_binding_1 "HMMPfam_Hemopexin;superfamily_Hemopexin-like domain;HMMPfam_Peptidase_M10;HMMPfam_PG_binding_1;superfamily_PGBD-like;superfamily_Metalloproteases (""zincins"") catalytic domain" - no_errors VPS11 55823 genome.wustl.edu 36 11 118446271 118446271 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 118446271 118446271 C G SNP VPS11 ENST00000300793 human ensembl 54_36p 1 known missense c.587 p.A196G 0.99 NULL HMMPfam_zf-C3HC4;superfamily_WD40 repeat-like;superfamily_ARM repeat;superfamily_Protein prenylyltransferase;superfamily_RING/U-box - no_errors SORL1 6653 genome.wustl.edu 36 11 120967008 120967008 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 120967008 120967008 C T SNP SORL1 NM_003105 human genbank 54_36p 1 reviewed silent c.4302 p.D1434 1 HMMPfam_Ldl_recept_a HMMPfam_Ldl_recept_b;HMMPfam_Ldl_recept_a;HMMPfam_BNR;HMMPfam_fn3;superfamily_Fibronectin type III;superfamily_Oligoxyloglucan reducing end-specific cellobiohydrolase;superfamily_EGF/Laminin;superfamily_LDL receptor-like module;superfamily_YWTD domain - no_errors NAP1L4 4676 genome.wustl.edu 36 11 2937577 2937577 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 2937577 2937577 C T SNP NAP1L4 NM_005969 human genbank 54_36p -1 reviewed missense c.745 p.G249R 1 HMMPfam_NAP superfamily_ARM repeat;HMMPfam_NAP - no_errors DAGLA 747 genome.wustl.edu 36 11 61267804 61267804 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 61267804 61267804 G C SNP DAGLA NM_006133 human genbank 54_36p 1 validated missense c.2396 p.G799A 1 NULL HMMPfam_Lipase_3,superfamily_alpha/beta-Hydrolases - no_errors C11orf42 160298 genome.wustl.edu 36 11 6188395 6188395 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 6188395 6188395 C A SNP C11orf42 NM_173525 human genbank 54_36p 1 predicted missense c.812 p.P271H 0.99 NULL - - no_errors HEPHL1 341208 genome.wustl.edu 36 11 93394202 93394202 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 11 93394202 93394202 C T SNP HEPHL1 NM_001098672 human genbank 54_36p 1 validated missense c.20 p.A7V 0.51 NULL - - no_errors DNAH10 196385 genome.wustl.edu 36 12 122838342 122838342 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 122838342 122838342 C A SNP DNAH10 NM_207437 human genbank 54_36p 1 validated missense c.731 p.A244D 0.996 NULL - - no_errors TMEM132D 121256 genome.wustl.edu 36 12 128124816 128124816 + Nonsense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 128124816 128124816 C A SNP TMEM132D NM_133448 human genbank 54_36p -1 validated nonsense c.2857 p.E953* 0.92 NULL - - no_errors PLEKHA5 54477 genome.wustl.edu 36 12 19414000 19414000 + Splice_Site SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 19414000 19414000 G C SNP PLEKHA5 NM_019012 human genbank 54_36p 1 validated splice_site c.3351+1 e25+1 1 - - - no_errors SOX5 6660 genome.wustl.edu 36 12 23578429 23578429 + Missense_Mutation SNP T T A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 23578429 23578429 T A SNP SOX5 NM_006940 human genbank 54_36p -1 reviewed missense c.2283 p.Q761H 1 NULL HMMPfam_HMG_box;superfamily_HMG-box - no_errors SLC2A13 114134 genome.wustl.edu 36 12 38510252 38510252 + Nonsense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 38510252 38510252 G T SNP SLC2A13 NM_052885 human genbank 54_36p -1 validated nonsense c.1308 p.Y436* 1 HMMPfam_Sugar_tr HMMPfam_Sugar_tr;superfamily_MFS general substrate transporter;superfamily_Plexin repeat - no_errors ANP32D 23519 genome.wustl.edu 36 12 47153049 47153051 + In_Frame_Del DEL TAG TAG - Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 TAG TAG TAG - TAG TAG Unknown Valid Somatic Phase_III Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 47153049 47153051 TAG - DEL ANP32D NM_012404 human genbank 54_36p 1 reviewed in_frame_del c.335_337 p.LENLE112in_frame_del* 1.000:1.000:1.000 NULL superfamily_Outer arm dynein light chain 1 (deletion:cds_exon[47152715,47153110]) no_errors NEUROD4 58158 genome.wustl.edu 36 12 53707449 53707449 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 53707449 53707449 G T SNP NEUROD4 NM_021191 human genbank 54_36p 1 validated missense c.959 p.G320V 0.05 NULL - - no_errors LOC387867 387867 genome.wustl.edu 36 12 67233142 67233142 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 67233142 67233142 G T SNP LOC387867 XM_001726521 human genbank 54_36p -1 model missense c.788 p.P263H 1 NULL - - pseudogene PZP 5858 genome.wustl.edu 36 12 9246536 9246536 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 9246536 9246536 G C SNP PZP NM_002864 human genbank 54_36p -1 validated missense c.279 p.I93M HMMPfam_A2M_N HMMPfam_A2M;HMMPfam_A2M_N;superfamily_Terpenoid cyclases/Protein prenyltransferases;superfamily_Invasin/intimin cell-adhesion fragments;HMMPfam_A2M_recep;superfamily_Alpha-macroglobulin receptor domain;HMMPfam_A2M_N_2;HMMPfam_A2M_comp - no_errors CRADD 8738 genome.wustl.edu 36 12 92596747 92596747 + Silent SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 12 92596747 92596747 G T SNP CRADD NM_003805 human genbank 54_36p 1 reviewed silent c.66 p.V22 1 NULL - - no_errors NALCN 259232 genome.wustl.edu 36 13 100515868 100515868 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 13 100515868 100515868 C T SNP NALCN NM_052867 human genbank 54_36p -1 validated missense c.4493 p.R1498H 1 NULL HMMPfam_Ion_trans;superfamily_Voltage-gated potassium channels - no_errors MTMR6 9107 genome.wustl.edu 36 13 24729942 24729942 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 13 24729942 24729942 C T SNP MTMR6 NM_004685 human genbank 54_36p -1 validated missense c.901 p.G301S 1 NULL HMMPfam_Myotub-related;superfamily_PH domain-like;superfamily_(Phosphotyrosine protein) phosphatases II - no_errors TRIM13 10206 genome.wustl.edu 36 13 49484660 49484660 + Nonsense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 13 49484660 49484660 C T SNP TRIM13 NM_001007278 human genbank 54_36p 1 reviewed nonsense c.592 p.Q198* 1 NULL - - no_errors CPNE6 9362 genome.wustl.edu 36 14 23616333 23616333 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 14 23616333 23616333 C G SNP CPNE6 NM_006032 human genbank 54_36p 1 reviewed missense c.1430 p.S477C 0.99 NULL HMMPfam_C2;superfamily_C2 domain (Calcium/lipid-binding domain CaLB);HMMPfam_Copine;superfamily_vWA-like - no_errors SEC23A 10484 genome.wustl.edu 36 14 38581817 38581817 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 14 38581817 38581817 A G SNP SEC23A NM_006364 human genbank 54_36p -1 reviewed missense c.1910 p.L637P 1 HMMPfam_Gelsolin HMMPfam_zf-Sec23_Sec24;HMMPfam_Sec23_trunk;HMMPfam_Sec23_helical;HMMPfam_Gelsolin;HMMPfam_Sec23_BS;superfamily_vWA-like;superfamily_Helical domain of Sec23/24;superfamily_beta-sandwich domain of Sec23/24;superfamily_C-terminal gelsolin-like domain of Sec23/24;superfamily_Zn-finger domain of Sec23/24 - no_errors SEL1L 6400 genome.wustl.edu 36 14 81034573 81034573 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 14 81034573 81034573 C T SNP SEL1L NM_005065 human genbank 54_36p -1 validated missense c.910 p.G304S 1 HMMPfam_Sel1 HMMPfam_fn2;HMMPfam_Sel1;superfamily_Kringle-like;superfamily_HCP-like - no_errors LOC643438 643438 genome.wustl.edu 36 7 147965567 147965567 + RNA SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 147965567 147965567 C T SNP LOC643438 XR_015310 human genbank 54_36p 1 model rna NULL NULL 1 - - - no_errors SPINT1 6692 genome.wustl.edu 36 15 38933038 38933038 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 15 38933038 38933038 G C SNP SPINT1 NM_181642 human genbank 54_36p 1 reviewed missense c.663 p.Q221H 1 NULL HMMPfam_Ldl_recept_a;HMMPfam_Kunitz_BPTI;superfamily_BPTI-like;HMMPfam_MANEC;superfamily_LDL receptor-like module - no_errors C15orf48 84419 genome.wustl.edu 36 15 43510545 43510545 + Missense_Mutation SNP G G C Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic Phase_III Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 15 43510545 43510545 G C SNP C15orf48 NM_032413 human genbank 54_36p 1 validated missense c.91 p.A31P 0.002 NULL - - no_errors MYEF2 50804 genome.wustl.edu 36 15 46245454 46245454 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 15 46245454 46245454 C G SNP MYEF2 NM_016132 human genbank 54_36p -1 validated missense c.493 p.D165H 1 HMMPfam_RRM_1 HMMPfam_RRM_1;superfamily_RNA-binding domain RBD - no_errors CCPG1 9236 genome.wustl.edu 36 15 53439566 53439566 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 15 53439566 53439566 A G SNP CCPG1 NM_004748 human genbank 54_36p -1 validated missense c.1697 p.F566S NULL - - no_errors BNIP2 663 genome.wustl.edu 36 15 57752127 57752127 + Splice_Site SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 15 57752127 57752127 C A SNP BNIP2 NM_004330 human genbank 54_36p -1 reviewed splice_site c.575+1 e5+1 1 - - - no_errors UNC45A 55898 genome.wustl.edu 36 15 89290898 89290898 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 15 89290898 89290898 C T SNP UNC45A NM_018671 human genbank 54_36p 1 validated missense c.1250 p.T417M 1 NULL HMMPfam_Arm;HMMPfam_TPR_1;HMMPfam_TPR_2;superfamily_ARM repeat;superfamily_TPR-like - no_errors RNPS1 10921 genome.wustl.edu 36 16 2252307 2252307 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 16 2252307 2252307 C T SNP RNPS1 NM_006711 human genbank 54_36p -1 reviewed missense c.649 p.E217K 1 HMMPfam_RRM_1 HMMPfam_RRM_1;superfamily_RNA-binding domain RBD - no_errors CES1 1066 genome.wustl.edu 36 16 54415073 54415073 + Silent SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 16 54415073 54415073 C A SNP CES1 NM_001025195 human genbank 54_36p -1 reviewed silent c.429 p.G143 0.99 HMMPfam_COesterase HMMPfam_COesterase;superfamily_alpha/beta-Hydrolases - no_errors ZFP90 146198 genome.wustl.edu 36 16 67155003 67155003 + Missense_Mutation SNP A A T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 16 67155003 67155003 A T SNP ZFP90 NM_133458 human genbank 54_36p 1 provisional missense c.812 p.E271V 0.16 NULL - - no_errors MYH8 4626 genome.wustl.edu 36 17 10244771 10244771 + Silent SNP T T A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 10244771 10244771 T A SNP MYH8 NM_002472 human genbank 54_36p -1 validated silent c.3396 p.R1132 1 HMMPfam_Myosin_tail_1 HMMPfam_IQ;HMMPfam_Myosin_head;HMMPfam_Myosin_tail_1;HMMPfam_Myosin_N;superfamily_Prefoldin;superfamily_t-snare proteins;superfamily_Spectrin repeat;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors MYH4 4622 genome.wustl.edu 36 17 10304029 10304029 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 10304029 10304029 C G SNP MYH4 NM_017533 human genbank 54_36p -1 validated missense c.1381 p.G461R 1 HMMPfam_Myosin_head HMMPfam_IQ;HMMPfam_Myosin_head;HMMPfam_Myosin_tail_1;HMMPfam_Myosin_N;superfamily_Prefoldin;superfamily_Spectrin repeat;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors KRT25 147183 genome.wustl.edu 36 17 36163715 36163715 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 36163715 36163715 G T SNP KRT25 NM_181534 human genbank 54_36p -1 provisional missense c.592 p.L198M 1 NULL - - no_errors LOC644397 644397 genome.wustl.edu 36 17 42451708 42451708 + RNA SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 42451708 42451708 C T SNP LOC644397 XR_042323 human genbank 54_36p 1 model rna NULL NULL - - - pseudogene DNAI2 64446 genome.wustl.edu 36 17 69797457 69797457 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 69797457 69797457 C T SNP DNAI2 NM_023036 human genbank 54_36p 1 validated silent c.597 p.Y199 1 NULL HMMPfam_WD40;superfamily_WD40 repeat-like - no_errors TP53 7157 genome.wustl.edu 36 17 7518929 7518929 + Missense_Mutation SNP A T T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A T T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 7518929 7518929 A T SNP TP53 NM_000546 human genbank 54_36p -1 reviewed missense c.645 p.S215R 0.99 HMMPfam_P53 superfamily_p53-like transcription factors;superfamily_p53 tetramerization domain;P53_tetramer;HMMPfam_P53_tetramer;P53;HMMPfam_P53;P53_TAD;HMMPfam_P53_TAD - no_errors RNF213 57674 genome.wustl.edu 36 17 75932281 75932281 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 75932281 75932281 C G SNP RNF213 NM_020914 human genbank 54_36p 1 validated missense c.432 p.F144L 1 NULL HMMPfam_zf-C3HC4;superfamily_P-loop containing nucleoside triphosphate hydrolases;superfamily_Nickel-iron hydrogenase small subunit;superfamily_RING/U-box - no_errors USP43 124739 genome.wustl.edu 36 17 9572024 9572024 + Silent SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 17 9572024 9572024 G T SNP USP43 NM_153210 human genbank 54_36p 1 validated silent c.2364 p.R788 0.04 NULL - - no_errors RGL3 57139 genome.wustl.edu 36 19 11388320 11388320 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 19 11388320 11388320 C T SNP RGL3 NM_001035223 human genbank 54_36p -1 provisional silent c.393 p.A131 HMMPfam_RasGEF_N HMMPfam_RA;HMMPfam_RasGEF_N;HMMPfam_RasGEF;superfamily_Ras GEF;superfamily_Ubiquitin-like - no_errors FKBP8 23770 genome.wustl.edu 36 19 18510133 18510133 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 19 18510133 18510133 G C SNP FKBP8 NM_012181 human genbank 54_36p -1 reviewed missense c.665 p.A222G 1 NULL HMMPfam_FKBP_C;HMMPfam_TPR_1;superfamily_TPR-like;superfamily_FKBP-like - no_errors PHLDB3 653583 genome.wustl.edu 36 19 48682628 48682628 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 19 48682628 48682628 C T SNP PHLDB3 NM_198850 human genbank 54_36p -1 validated silent c.1401 p.A467 0.48 NULL - - no_errors AURKC 6795 genome.wustl.edu 36 19 62438448 62438448 + Missense_Mutation SNP T T G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 19 62438448 62438448 T G SNP AURKC NM_001015878 human genbank 54_36p 1 reviewed missense c.781 p.S261A HMMPfam_Pkinase HMMPfam_Pkinase;superfamily_Protein kinase-like (PK-like) - no_errors TBC1D8 11138 genome.wustl.edu 36 2 101021355 101021355 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 101021355 101021355 C A SNP TBC1D8 NM_001102426 human genbank 54_36p -1 validated missense c.1230 p.M410I 0.98 NULL - - no_errors IL1F7 27178 genome.wustl.edu 36 2 113391711 113391711 + Silent SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 113391711 113391711 G A SNP IL1F7 NM_014439 human genbank 54_36p 1 reviewed silent c.294 p.L98 NULL - - no_errors LCT 3938 genome.wustl.edu 36 2 136283476 136283476 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 136283476 136283476 C A SNP LCT NM_002299 human genbank 54_36p -1 reviewed missense c.2911 p.V971L 1 HMMPfam_Glyco_hydro_1 HMMPfam_Glyco_hydro_1;superfamily_(Trans)glycosidases - no_errors TPO 7173 genome.wustl.edu 36 2 1470757 1470757 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 1470757 1470757 C A SNP TPO NM_000547 human genbank 54_36p 1 reviewed missense c.1755 p.D585E 1 HMMPfam_An_peroxidase HMMPfam_Sushi;HMMPfam_An_peroxidase;superfamily_Heme-dependent peroxidases;HMMPfam_EGF_CA;superfamily_EGF/Laminin;superfamily_Complement control module/SCR domain - no_errors LOC643997 643997 genome.wustl.edu 36 2 174058986 174058986 + Silent SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 174058986 174058986 G C SNP LOC643997 XM_292963 human genbank 54_36p -1 model silent c.351 p.A117 1 NULL - - no_errors PLEKHA3 65977 genome.wustl.edu 36 2 179058628 179058628 + Missense_Mutation SNP T T A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 179058628 179058628 T A SNP PLEKHA3 NM_019091 human genbank 54_36p 1 validated missense c.55 p.W19R 1 NULL - - no_errors MPP4 58538 genome.wustl.edu 36 2 202258973 202258973 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 202258973 202258973 G C SNP MPP4 NM_033066 human genbank 54_36p -1 reviewed missense c.406 p.P136A 1 NULL - - no_errors ABCA12 26154 genome.wustl.edu 36 2 215548940 215548940 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 215548940 215548940 A G SNP ABCA12 NM_173076 human genbank 54_36p -1 reviewed missense c.5195 p.I1732T 0.96 NULL HMMPfam_ABC_tran;superfamily_Spectrin repeat;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors CCDC88A 55704 genome.wustl.edu 36 2 55389610 55389610 + Missense_Mutation SNP T T C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 55389610 55389610 T C SNP CCDC88A NM_018084 human genbank 54_36p -1 validated missense c.4226 p.D1409G 1 NULL - - no_errors CCT4 10575 genome.wustl.edu 36 2 61953162 61953162 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 61953162 61953162 C T SNP CCT4 NM_006430 human genbank 54_36p -1 validated silent c.1191 p.V397 1 HMMPfam_Cpn60_TCP1 HMMPfam_Cpn60_TCP1;superfamily_GroEL equatorial domain-like;superfamily_GroEL apical domain-like;superfamily_GroEL-intermediate domain like - no_errors REV1 51455 genome.wustl.edu 36 2 99421715 99421715 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 2 99421715 99421715 C T SNP REV1 NM_016316 human genbank 54_36p -1 reviewed silent c.993 p.T331 0.05 NULL HMMPfam_IMS;HMMPfam_BRCT;superfamily_Lesion bypass DNA polymerase (Y-family) little finger domain;superfamily_BRCT domain;superfamily_DNA/RNA polymerases - no_errors BTBD3 22903 genome.wustl.edu 36 20 11851398 11851398 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 20 11851398 11851398 C G SNP BTBD3 NM_014962 human genbank 54_36p 1 validated missense c.653 p.T218S 1 NULL - - no_errors TPX2 22974 genome.wustl.edu 36 20 29821902 29821902 + Missense_Mutation SNP T T C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 20 29821902 29821902 T C SNP TPX2 NM_012112 human genbank 54_36p 1 validated missense c.452 p.I151T NULL HMMPfam_TPX2;HMMPfam_Aurora-A_bind - no_errors RNF114 55905 genome.wustl.edu 36 20 47991590 47991590 + Nonsense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 20 47991590 47991590 C T SNP RNF114 NM_018683 human genbank 54_36p 1 validated nonsense c.226 p.R76* 0.99 NULL - - no_errors PAK7 57144 genome.wustl.edu 36 20 9494755 9494755 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 20 9494755 9494755 G C SNP PAK7 NM_020341 human genbank 54_36p -1 reviewed missense c.1267 p.Q423E 1 NULL PBD;HMMPfam_PBD;Pkinase;HMMPfam_Pkinase - no_errors NCAM2 4685 genome.wustl.edu 36 21 21632585 21632585 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 21 21632585 21632585 C T SNP NCAM2 NM_004540 human genbank 54_36p 1 reviewed missense c.904 p.P302S 1 NULL HMMPfam_fn3;superfamily_Fibronectin type III;HMMPfam_I-set;HMMPfam_ig;superfamily_Immunoglobulin - no_errors APP 351 genome.wustl.edu 36 21 26406308 26406308 + Silent SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 21 26406308 26406308 C A SNP APP NM_000484 human genbank 54_36p -1 reviewed silent c.84 p.L28 1 HMMPfam_A4_EXTRA HMMPfam_Kunitz_BPTI;superfamily_BPTI-like;HMMPfam_A4_EXTRA;superfamily_Amyloid beta a4 protein copper binding domain (domain 2);HMMPfam_Beta-APP;superfamily_A heparin-binding domain;superfamily_CAPPD an extracellular domain of amyloid beta A4 protein - no_errors CLDN17 26285 genome.wustl.edu 36 21 30460663 30460663 + Missense_Mutation SNP T T A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 21 30460663 30460663 T A SNP CLDN17 NM_012131 human genbank 54_36p -1 provisional missense c.144 p.E48D 1 NULL - - no_errors TBX1 6899 genome.wustl.edu 36 22 18131755 18131755 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 22 18131755 18131755 C T SNP TBX1 NM_080647 human genbank 54_36p 1 reviewed missense c.590 p.P197L 1 HMMPfam_T-box HMMPfam_T-box;superfamily_p53-like transcription factors - no_errors GGT5 2687 genome.wustl.edu 36 22 22945945 22945945 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 22 22945945 22945945 C A SNP GGT5 NM_001099781 human genbank 54_36p -1 reviewed missense c.1757 p.G586V 0.98 NULL - - no_errors IGSF10 285313 genome.wustl.edu 36 3 152647214 152647214 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 3 152647214 152647214 G C SNP IGSF10 NM_178822 human genbank 54_36p -1 provisional missense c.3245 p.P1082R 0.02 NULL - - no_errors PHC3 80012 genome.wustl.edu 36 3 171329851 171329851 + Missense_Mutation SNP T T G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 3 171329851 171329851 T G SNP PHC3 NM_024947 human genbank 54_36p -1 validated missense c.1103 p.Q368P 0.96 NULL - - no_errors OR5K2 402135 genome.wustl.edu 36 3 99699836 99699836 + Missense_Mutation SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 3 99699836 99699836 G A SNP OR5K2 NM_001004737 human genbank 54_36p 1 provisional missense c.622 p.V208I NULL - - no_errors ADAM29 11086 genome.wustl.edu 36 4 176134255 176134255 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 176134255 176134255 G T SNP ADAM29 NM_014269 human genbank 54_36p 1 reviewed missense c.1004 p.G335V 0.56 HMMPfam_Reprolysin HMMPfam_Reprolysin;HMMPfam_Disintegrin;HMMPfam_Pep_M12B_propep;HMMPfam_ADAM_CR - no_errors ADAM29 11086 genome.wustl.edu 36 4 176134344 176134344 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 176134344 176134344 A G SNP ADAM29 NM_014269 human genbank 54_36p 1 reviewed missense c.1093 p.K365E HMMPfam_Reprolysin HMMPfam_Reprolysin;HMMPfam_Disintegrin;HMMPfam_Pep_M12B_propep;HMMPfam_ADAM_CR - no_errors FAT1 2195 genome.wustl.edu 36 4 187867227 187867227 + Missense_Mutation SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 187867227 187867227 G A SNP FAT1 NM_005245 human genbank 54_36p -1 reviewed missense c.749 p.A250V 1 NULL - - no_errors TLR1 7096 genome.wustl.edu 36 4 38475422 38475422 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 38475422 38475422 C T SNP TLR1 NM_003263 human genbank 54_36p -1 reviewed missense c.1426 p.A476T 0.96 NULL - - no_errors HMX1 3166 genome.wustl.edu 36 4 43601 43601 + Silent SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 43601 43601 G A SNP HMX1 NM_018942 human genbank 54_36p -1 validated silent c.372 p.C124 0 NULL - - no_start_codon:pseudogene:no_stop_codon CEP135 9662 genome.wustl.edu 36 4 56572877 56572877 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 56572877 56572877 G T SNP CEP135 NM_025009 human genbank 54_36p 1 validated missense c.2771 p.R924I 1 NULL - - no_errors HPSE 10855 genome.wustl.edu 36 4 84450939 84450939 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 4 84450939 84450939 C T SNP HPSE NM_001098540 human genbank 54_36p -1 validated missense c.802 p.V268I 0.51 NULL - - no_errors TSSK1B 83942 genome.wustl.edu 36 5 112797869 112797869 + Silent SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 112797869 112797869 G A SNP TSSK1B NM_032028 human genbank 54_36p -1 provisional silent c.567 p.G189 0.738 HMMPfam_Pkinase HMMPfam_Pkinase,superfamily_Protein kinase-like (PK-like) - no_errors DMXL1 1657 genome.wustl.edu 36 5 118513074 118513074 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 118513074 118513074 C G SNP DMXL1 NM_005509 human genbank 54_36p 1 validated missense c.3653 p.S1218C 1 NULL - - no_errors MEGF10 84466 genome.wustl.edu 36 5 126760282 126760282 + Missense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 126760282 126760282 G C SNP MEGF10 NM_032446 human genbank 54_36p 1 validated missense c.572 p.C191S 1 NULL - - no_errors LOC643300 643300 genome.wustl.edu 36 5 21918591 21918591 + RNA SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 21918591 21918591 C A SNP LOC643300 XR_016534 human genbank 54_36p 1 model rna NULL NULL 1 - - - pseudogene RNASEN 29102 genome.wustl.edu 36 5 31485177 31485177 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 31485177 31485177 C G SNP RNASEN NM_013235 human genbank 54_36p -1 validated missense c.2789 p.R930T 1 NULL HMMPfam_Ribonuclease_3;superfamily_RNase III catalytic domain-like (Pfam 00636);HMMPfam_dsrm;superfamily_dsRNA-binding domain-like - no_errors GOLPH3 64083 genome.wustl.edu 36 5 32162087 32162087 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 32162087 32162087 C T SNP GOLPH3 NM_022130 human genbank 54_36p -1 reviewed silent c.885 p.A295 0.02 HMMPfam_GPP34 HMMPfam_GPP34 - no_errors LOC728553 728553 genome.wustl.edu 36 5 33198391 33198391 + RNA SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 33198391 33198391 C A SNP LOC728553 XR_015414 human genbank 54_36p 1 model rna NULL NULL 1 - - - pseudogene SKP2 6502 genome.wustl.edu 36 5 36216135 36216135 + Missense_Mutation SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 5 36216135 36216135 G A SNP SKP2 ENST00000308927 human ensembl 54_36p 1 known missense c.1147 p.G383R 0.01 NULL HMMPfam_F-box;HMMPfam_LRR_2;superfamily_RNI-like;superfamily_F-box domain - no_errors LOC442160 442160 genome.wustl.edu 36 6 10322307 10322307 + RNA SNP T T C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 10322307 10322307 T C SNP LOC442160 XR_042339 human genbank 54_36p -1 model rna NULL NULL 1 - - - pseudogene HS3ST5 222537 genome.wustl.edu 36 6 114486016 114486016 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 114486016 114486016 G T SNP HS3ST5 NM_153612 human genbank 54_36p -1 validated missense c.139 p.L47M 1 NULL HMMPfam_Sulfotransfer_1;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors ROS1 6098 genome.wustl.edu 36 6 117817288 117817288 + Silent SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 117817288 117817288 G T SNP ROS1 NM_002944 human genbank 54_36p -1 reviewed silent c.1677 p.G559 HMMPfam_fn3 Pkinase_Tyr;HMMPfam_Pkinase_Tyr;fn3;HMMPfam_fn3;Fibronectin type III;superfamily_Fibronectin type III;Protein kinase-like (PK-like);superfamily_Protein kinase-like (PK-like);YWTD domain;superfamily_YWTD domain - no_errors HIST1H2BG 8339 genome.wustl.edu 36 6 26324802 26324802 + Missense_Mutation SNP T T C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 26324802 26324802 T C SNP HIST1H2BG NM_003518 human genbank 54_36p -1 reviewed missense c.49 p.K17E 1 NULL - - no_errors ZNF323 64288 genome.wustl.edu 36 6 28402343 28402343 + Missense_Mutation SNP T T A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 28402343 28402343 T A SNP ZNF323 NM_145909 human genbank 54_36p -1 validated missense c.800 p.Y267F HMMPfam_zf-C2H2 HMMPfam_SCAN;HMMPfam_zf-C2H2;superfamily_C2H2 and C2HC zinc fingers - no_errors NOTCH4 4855 genome.wustl.edu 36 6 32298323 32298323 + Missense_Mutation SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 32298323 32298323 G A SNP NOTCH4 NM_004557 human genbank 54_36p -1 reviewed missense c.394 p.R132C 0.97 HMMPfam_EGF HMMPfam_Notch;HMMPfam_Ank;superfamily_Ankyrin repeat;HMMPfam_EGF;superfamily_Concanavalin A-like lectins/glucanases;HMMPfam_NODP;HMMPfam_EGF_CA;superfamily_EGF/Laminin;superfamily_Notch domain - no_errors RING1 6015 genome.wustl.edu 36 6 33285759 33285759 + Missense_Mutation SNP T T G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 33285759 33285759 T G SNP RING1 NM_002931 human genbank 54_36p 1 reviewed missense c.329 p.I110S 1 NULL - - no_errors EXOC2 55770 genome.wustl.edu 36 6 578067 578067 + Missense_Mutation SNP C C A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 6 578067 578067 C A SNP EXOC2 NM_018303 human genbank 54_36p -1 reviewed missense c.169 p.A57S 1 NULL - - no_errors ASZ1 136991 genome.wustl.edu 36 7 116808353 116808353 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 116808353 116808353 C G SNP ASZ1 NM_130768 human genbank 54_36p -1 validated missense c.893 p.R298T 0.98 HMMPfam_SAM_2 HMMPfam_Ank;superfamily_Ankyrin repeat;superfamily_SAM/Pointed domain;HMMPfam_SAM_2 - no_errors BRAF 673 genome.wustl.edu 36 7 140095638 140095638 + Nonsense_Mutation SNP G G C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 140095638 140095638 G C SNP BRAF NM_004333 human genbank 54_36p -1 reviewed nonsense c.1910 p.S637* 1 HMMPfam_Pkinase Pkinase;HMMPfam_Pkinase;C1_1;HMMPfam_C1_1;RBD;HMMPfam_RBD - no_errors ZNF398 57541 genome.wustl.edu 36 7 148482062 148482062 + Silent SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 148482062 148482062 A G SNP ZNF398 NM_170686 human genbank 54_36p 1 reviewed silent c.117 p.A39 0.9 NULL - - no_errors KCNH2 3757 genome.wustl.edu 36 7 150280856 150280856 + Missense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 150280856 150280856 C T SNP KCNH2 NM_000238 human genbank 54_36p -1 reviewed missense c.1147 p.D383N 0.993 NULL - - no_errors PTPRN2 5799 genome.wustl.edu 36 7 157652543 157652543 + Missense_Mutation SNP C C G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 157652543 157652543 C G SNP PTPRN2 NM_002847 human genbank 54_36p -1 reviewed missense c.751 p.A251P 0.734 NULL HMMPfam_Y_phosphatase,superfamily_(Phosphotyrosine protein) phosphatases II - no_errors GRM3 2913 genome.wustl.edu 36 7 86306252 86306252 + Missense_Mutation SNP T T A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 86306252 86306252 T A SNP GRM3 NM_000840 human genbank 54_36p 1 reviewed missense c.1486 p.S496T 0.64 NULL HMMPfam_ANF_receptor;HMMPfam_NCD3G;superfamily_Periplasmic binding protein-like I;superfamily_TNF receptor-like;HMMPfam_7tm_3 - no_errors CSMD1 64478 genome.wustl.edu 36 8 3204122 3204122 + Nonsense_Mutation SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 8 3204122 3204122 C T SNP CSMD1 NM_033225 human genbank 54_36p -1 validated nonsense c.3267 p.W1089* 1 NULL - - pseudogene:no_stop_codon:bad_bp_length_for_coding_region GOT1L1 137362 genome.wustl.edu 36 8 37912392 37912392 + Missense_Mutation SNP A A G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 8 37912392 37912392 A G SNP GOT1L1 ENST00000307599 human ensembl 54_36p -1 known missense c.914 p.L305P 0.98 NULL - - no_errors CHD7 55636 genome.wustl.edu 36 8 61905599 61905599 + Silent SNP T T G novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 8 61905599 61905599 T G SNP CHD7 NM_017780 human genbank 54_36p 1 reviewed silent c.3687 p.L1229 1 HMMPfam_SNF2_N HMMPfam_SNF2_N;HMMPfam_Chromo;HMMPfam_Helicase_C;HMMPfam_TCH;superfamily_P-loop containing nucleoside triphosphate hydrolases;superfamily_Chromo domain-like - no_errors PLEKHF2 79666 genome.wustl.edu 36 8 96235865 96235865 + Missense_Mutation SNP G G T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 8 96235865 96235865 G T SNP PLEKHF2 NM_024613 human genbank 54_36p 1 provisional missense c.417 p.K139N 1 NULL - - no_errors ZBTB43 23099 genome.wustl.edu 36 9 128635971 128635971 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 9 128635971 128635971 C T SNP ZBTB43 NM_014007 human genbank 54_36p 1 validated silent c.1362 p.Y454 1 NULL HMMPfam_zf-C2H2;HMMPfam_BTB;superfamily_POZ domain;superfamily_C2H2 and C2HC zinc fingers - no_errors FREM1 158326 genome.wustl.edu 36 9 14838670 14838670 + Missense_Mutation SNP C A A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C A A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 9 14838670 14838670 C A SNP FREM1 NM_144966 human genbank 54_36p -1 validated missense c.1254 p.W418C 1 NULL - - no_errors BAG1 573 genome.wustl.edu 36 9 33245264 33245264 + Nonsense_Mutation SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 9 33245264 33245264 G A SNP BAG1 NM_004323 human genbank 54_36p -1 reviewed nonsense c.991 p.Q331* 1 NULL HMMPfam_ubiquitin;HMMPfam_BAG;superfamily_Ubiquitin-like;superfamily_BAG domain - no_errors MIR489 574442 genome.wustl.edu 36 7 92951240 92951240 + RNA SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 7 92951240 92951240 G A SNP MIRN489 ENST00000384923 human ensembl 54_36p -1 known rna NULL NULL 1 - - - no_errors SLC38A5 92745 genome.wustl.edu 36 X 48209620 48209620 + Missense_Mutation SNP G G A novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 X 48209620 48209620 G A SNP SLC38A5 NM_033518 human genbank 54_36p -1 validated missense c.353 p.A118V 1 NULL - - no_errors CXorf67 340602 genome.wustl.edu 36 X 51168014 51168014 + Missense_Mutation SNP T T C novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 X 51168014 51168014 T C SNP LOC340602 NM_203407 human genbank 54_36p 1 predicted missense c.1406 p.L469P NULL - - no_errors USP51 158880 genome.wustl.edu 36 X 55530169 55530169 + Silent SNP C C T novel Unknown TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 21b50b8c-781a-4e15-a4ad-715f416f0fa2 2655367b-70ac-471d-bcfa-2fbf59e0d4f7 X 55530169 55530169 C T SNP USP51 NM_201286 human genbank 54_36p -1 validated silent c.1929 p.V643 0.002 HMMPfam_UCH HMMPfam_UCH,superfamily_Cysteine proteinases - no_errors