Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error ADORA3 140 genome.wustl.edu 36 1 111844530 111844530 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 111844530 111844530 C A SNP ADORA3 NM_000677 human genbank 54_36p -1 reviewed missense c.522 p.M174I 1 NULL - - no_errors SPTA1 6708 genome.wustl.edu 36 1 156904273 156904273 + Missense_Mutation SNP T T G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 156904273 156904273 T G SNP SPTA1 NM_003126 human genbank 54_36p -1 reviewed missense c.2037 p.K679N 1 NULL - - no_errors ATF6 22926 genome.wustl.edu 36 1 160088228 160088228 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 160088228 160088228 T C SNP ATF6 NM_007348 human genbank 54_36p 1 validated missense c.1412 p.I471T 0.18 NULL - - no_errors SPEN 23013 genome.wustl.edu 36 1 16075631 16075631 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 16075631 16075631 G C SNP SPEN NM_015001 human genbank 54_36p 1 reviewed missense c.752 p.R251T 1 NULL HMMPfam_RRM_1;HMMPfam_SPOC;superfamily_SPOC domain-like;superfamily_RNA-binding domain RBD - no_errors RNASEL 6041 genome.wustl.edu 36 1 180812026 180812026 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture Sanger_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 180812026 180812026 T C SNP RNASEL NM_021133 human genbank 54_36p -1 reviewed missense c.2027 p.E676G 0 NULL - - no_errors PLA2G4A 5321 genome.wustl.edu 36 1 185186473 185186473 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 185186473 185186473 C G SNP PLA2G4A NM_024420 human genbank 54_36p 1 reviewed missense c.1326 p.H442Q 0.96 HMMPfam_PLA2_B superfamily_C2 domain (Calcium/lipid-binding domain CaLB);superfamily_FabD/lysophospholipase-like;HMMPfam_C2;HMMPfam_PLA2_B - no_errors UBR4 23352 genome.wustl.edu 36 1 19314710 19314710 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 19314710 19314710 C A SNP UBR4 NM_020765 human genbank 54_36p -1 validated missense c.10832 p.R3611L 1 NULL - - no_errors KIAA0090 23065 genome.wustl.edu 36 1 19438993 19438993 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 19438993 19438993 G A SNP KIAA0090 NM_015047 human genbank 54_36p -1 predicted missense c.860 p.S287F 0.88 NULL - - no_errors C1orf107 27042 genome.wustl.edu 36 1 208070891 208070893 + In_Frame_Del DEL GAG GAG - novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 GAG GAG GAG - GAG GAG Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 208070891 208070893 GAG - DEL C1orf107 NM_014388 human genbank 54_36p 1 validated in_frame_del c.268_270 p.E93in_frame_del 0.861:0.831:0.735 NULL - (deletion:cds_exon[208070771;208071011]) no_errors C1orf57 84284 genome.wustl.edu 36 1 231180580 231180580 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 231180580 231180580 G A SNP C1orf57 NM_032324 human genbank 54_36p 1 predicted missense c.553 p.V185M 0.66 NULL - - no_errors PUM1 9698 genome.wustl.edu 36 1 31211533 31211533 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 31211533 31211533 T C SNP PUM1 NM_001020658 human genbank 54_36p -1 reviewed missense c.1969 p.S657G 1 NULL - - no_errors GJB4 127534 genome.wustl.edu 36 1 35000167 35000167 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture Sanger_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 35000167 35000167 G T SNP GJB4 NM_153212 human genbank 54_36p 1 validated missense c.725 p.G242V 0 NULL - - no_errors LRRC7 57554 genome.wustl.edu 36 1 70277021 70277021 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 70277021 70277021 G C SNP LRRC7 NM_020794 human genbank 54_36p 1 validated missense c.2812 p.D938H 1 NULL HMMPfam_PDZ;superfamily_PDZ domain-like;HMMPfam_LRR_1;superfamily_RNI-like;superfamily_L domain-like - no_errors ACADM 34 genome.wustl.edu 36 1 75978367 75978367 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 75978367 75978367 G A SNP ACADM NM_000016 human genbank 54_36p 1 reviewed missense c.583 p.G195R 1 HMMPfam_Acyl-CoA_dh_M HMMPfam_Acyl-CoA_dh_1;HMMPfam_Acyl-CoA_dh_M;HMMPfam_Acyl-CoA_dh_N;superfamily_Acyl-CoA dehydrogenase C-terminal domain-like;superfamily_Acyl-CoA dehydrogenase NM domain-like - no_errors ENO1 2023 genome.wustl.edu 36 1 8849058 8849058 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 1 8849058 8849058 G A SNP ENO1 NM_001428 human genbank 54_36p -1 reviewed silent c.534 p.F178 1 HMMPfam_Enolase_C HMMPfam_Enolase_C;HMMPfam_Enolase_N;superfamily_Enolase C-terminal domain-like;superfamily_Enolase N-terminal domain-like - no_errors CACNB2 783 genome.wustl.edu 36 10 18827469 18827469 + Missense_Mutation SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 10 18827469 18827469 T A SNP CACNB2 ENST00000402317 human ensembl 54_36p 1 known missense c.351 p.F117L NULL - - no_errors DDX21 9188 genome.wustl.edu 36 10 70391886 70391886 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 10 70391886 70391886 C A SNP DDX21 NM_004728 human genbank 54_36p 1 reviewed missense c.574 p.P192T 1 NULL - - no_errors USP54 159195 genome.wustl.edu 36 10 74972831 74972831 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 10 74972831 74972831 G A SNP USP54 NM_152586 human genbank 54_36p -1 provisional missense c.440 p.A147V 1 NULL - - no_errors LARP4B 23185 genome.wustl.edu 36 10 865530 865530 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 10 865530 865530 C T SNP LARP5 NM_015155 human genbank 54_36p -1 provisional missense c.920 p.R307Q 1 NULL "HMMPfam_La;superfamily_""Winged helix"" DNA-binding domain;superfamily_RNA-binding domain RBD" - no_errors BIRC3 330 genome.wustl.edu 36 11 101700819 101700819 + Silent SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 11 101700819 101700819 A G SNP BIRC3 NM_001165 human genbank 54_36p 1 reviewed silent c.369 p.S123 NULL HMMPfam_CARD;HMMPfam_BIR;HMMPfam_zf-C3HC4;superfamily_DEATH domain;superfamily_Inhibitor of apoptosis (IAP) repeat - no_errors DYNC2H1 79659 genome.wustl.edu 36 11 102580816 102580816 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 11 102580816 102580816 C T SNP DYNC2H1 NM_001080463 human genbank 54_36p 1 provisional silent c.8367 p.F2789 1 NULL - - no_errors SLC17A6 57084 genome.wustl.edu 36 11 22337568 22337569 + Silent DNP CC CC AT novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 CC CC CC AT CC CC Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 11 22337568 22337569 CC AT DNP SLC17A6 NM_020346 human genbank 54_36p 1 validated silent c.492_493 p.STLN163 1.000:1.000 HMMPfam_MFS_1 HMMPfam_MFS_1;superfamily_MFS general substrate transporter - no_errors OR10Q1 219960 genome.wustl.edu 36 11 57752201 57752201 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 11 57752201 57752201 C T SNP OR10Q1 NM_001004471 human genbank 54_36p -1 provisional silent c.723 p.R241 0.42 NULL - - no_errors MAML2 84441 genome.wustl.edu 36 11 95351789 95351789 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 11 95351789 95351789 G A SNP MAML2 NM_032427 human genbank 54_36p -1 validated missense c.3442 p.L1148F 1 NULL - - no_errors POLR3B 55703 genome.wustl.edu 36 12 105281792 105281792 + Silent SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 12 105281792 105281792 G T SNP POLR3B NM_018082 human genbank 54_36p 1 provisional silent c.87 p.L29 1 NULL HMMPfam_RNA_pol_Rpb2_6;HMMPfam_RNA_pol_Rpb2_7;HMMPfam_RNA_pol_Rpb2_2;HMMPfam_RNA_pol_Rpb2_1;HMMPfam_RNA_pol_Rpb2_3;HMMPfam_RNA_pol_Rpb2_4;HMMPfam_RNA_pol_Rpb2_5;superfamily_beta and beta-prime subunits of DNA dependent RNA-polymerase - no_errors CIT 11113 genome.wustl.edu 36 12 118695044 118695044 + Silent SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 12 118695044 118695044 T C SNP CIT NM_007174 human genbank 54_36p -1 validated silent c.1995 p.A665 0.91 NULL HMMPfam_Pkinase;HMMPfam_Pkinase_C;HMMPfam_CNH;HMMPfam_PH;HMMPfam_C1_1;superfamily_Protein kinase-like (PK-like);superfamily_HR1 repeat;superfamily_PH domain-like;superfamily_Cysteine-rich domain - no_errors DNM1L 10059 genome.wustl.edu 36 12 32775673 32775673 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 12 32775673 32775673 G T SNP DNM1L NM_012062 human genbank 54_36p 1 reviewed missense c.1317 p.M439I 1 HMMPfam_Dynamin_M HMMPfam_Dynamin_M;HMMPfam_Dynamin_N;HMMPfam_GED;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors KRT2 3849 genome.wustl.edu 36 12 51325292 51325292 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 12 51325292 51325292 G A SNP KRT2 NM_000423 human genbank 54_36p -1 reviewed silent c.1698 p.G566 0.99 NULL HMMPfam_Filament;superfamily_Prefoldin - no_errors PPP1R12A 4659 genome.wustl.edu 36 12 78740067 78740067 + Missense_Mutation SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 12 78740067 78740067 A G SNP PPP1R12A NM_002480 human genbank 54_36p -1 reviewed missense c.827 p.I276T 1 NULL HMMPfam_Ank;superfamily_Ankyrin repeat - no_errors ENSG00000205940 0 genome.wustl.edu 36 4 12948665 12948665 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 12948665 12948665 G T SNP ENSG00000205940 ENST00000382444 human ensembl 54_36p 1 known missense c.918 p.E306D 1 NULL - - no_stop_codon:bad_bp_length_for_coding_region LOC283523 283523 genome.wustl.edu 36 13 18153787 18153787 + Nonsense_Mutation SNP A A T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 13 18153787 18153787 A T SNP LOC283523 XM_001714856 human genbank 54_36p 1 model nonsense c.1243 p.K415* 1 NULL - - pseudogene SACS 26278 genome.wustl.edu 36 13 22811133 22811133 + Nonsense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 13 22811133 22811133 G A SNP SACS NM_014363 human genbank 54_36p -1 validated nonsense c.4441 p.Q1481* 1 NULL - - no_errors B3GALTL 145173 genome.wustl.edu 36 13 30758859 30758859 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 13 30758859 30758859 C T SNP B3GALTL NM_194318 human genbank 54_36p 1 reviewed missense c.967 p.H323Y 1 HMMPfam_Fringe HMMPfam_Fringe - no_errors RB1 5925 genome.wustl.edu 36 13 47937211 47937211 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 13 47937211 47937211 G C SNP RB1 NM_000321 human genbank 54_36p 1 reviewed missense c.2288 p.R763T 1 HMMPfam_RB_B RB_B;HMMPfam_RB_B;RB_A;HMMPfam_RB_A;Rb_C;HMMPfam_Rb_C - no_errors PCDH9 5101 genome.wustl.edu 36 13 66103459 66103459 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 13 66103459 66103459 C T SNP PCDH9 NM_203487 human genbank 54_36p -1 reviewed missense c.3224 p.G1075D 1 NULL HMMPfam_Cadherin;HMMPfam_Cadherin_2;HMMPfam_Protocadherin;superfamily_Cadherin-like - no_errors LOC390413 390413 genome.wustl.edu 36 13 76453818 76453818 + RNA SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 13 76453818 76453818 C T SNP LOC390413 XR_017528 human genbank 54_36p -1 model rna NULL NULL 1 - - - pseudogene ADSSL1 122622 genome.wustl.edu 36 14 104282285 104282285 + Missense_Mutation SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 14 104282285 104282285 T A SNP ADSSL1 NM_199165 human genbank 54_36p 1 validated missense c.1294 p.F432I 1 HMMPfam_Adenylsucc_synt HMMPfam_Adenylsucc_synt,superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors METT11D1 64745 genome.wustl.edu 36 14 20534531 20534531 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 14 20534531 20534531 G A SNP METT11D1 NM_001029991 human genbank 54_36p 1 validated silent c.1086 p.K362 0.5 HMMPfam_Rsm22 HMMPfam_Rsm22;superfamily_S-adenosyl-L-methionine-dependent methyltransferases - no_errors SOS2 6655 genome.wustl.edu 36 14 49693585 49693585 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 14 49693585 49693585 C G SNP SOS2 NM_006939 human genbank 54_36p -1 validated missense c.1939 p.E647Q 1 HMMPfam_RasGEF_N HMMPfam_RhoGEF;HMMPfam_RasGEF_N;HMMPfam_PH;HMMPfam_RasGEF;HMMPfam_Histone;superfamily_Ras GEF;superfamily_Histone-fold;superfamily_DBL homology domain (DH-domain);superfamily_PH domain-like - no_errors MPP5 64398 genome.wustl.edu 36 14 66860274 66860274 + Missense_Mutation SNP A A T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 14 66860274 66860274 A T SNP MPP5 NM_022474 human genbank 54_36p 1 validated missense c.1843 p.N615Y 1 HMMPfam_Guanylate_kin superfamily_SH3-domain;HMMPfam_PDZ;superfamily_PDZ domain-like;HMMPfam_Guanylate_kin;HMMPfam_SH3_2;HMMPfam_L27;HMMPfam_L27_N;superfamily_L27 domain;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors TTC7B 145567 genome.wustl.edu 36 14 90266244 90266244 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 14 90266244 90266244 G T SNP TTC7B NM_001010854 human genbank 54_36p -1 provisional missense c.626 p.P209H 1 NULL HMMPfam_TPR_1;HMMPfam_TPR_2;superfamily_TPR-like - no_errors SMEK1 55671 genome.wustl.edu 36 14 91001386 91001386 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 14 91001386 91001386 C A SNP SMEK1 NM_032560 human genbank 54_36p -1 validated missense c.1752 p.M584I 1 NULL - - no_errors LOC100128116 100128116 genome.wustl.edu 36 5 146067018 146067018 + RNA SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 146067018 146067018 C G SNP LOC100128116 XR_039194 human genbank 54_36p -1 model rna NULL NULL 1 - - - pseudogene OR4N4 283694 genome.wustl.edu 36 15 19884234 19884234 + Nonsense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 15 19884234 19884234 C A SNP OR4N4 NM_001005241 human genbank 54_36p 1 provisional nonsense c.398 p.S133* NULL - - no_errors HERC2 8924 genome.wustl.edu 36 15 26132886 26132886 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 15 26132886 26132886 G A SNP HERC2 NM_004667 human genbank 54_36p -1 validated silent c.6486 p.L2162 1 NULL HMMPfam_RCC1;HMMPfam_ZZ;HMMPfam_HECT;superfamily_Spermadhesin CUB domain;HMMPfam_Cyt-b5;superfamily_Cytochrome b5-like heme/steroid binding domain;superfamily_Galactose-binding domain-like;superfamily_RCC1/BLIP-II;HMMPfam_MIB_HERC2;superfamily_Hect E3 ligase catalytic domain - no_errors SV2B 9899 genome.wustl.edu 36 15 89570923 89570923 + Silent SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 15 89570923 89570923 G C SNP SV2B NM_014848 human genbank 54_36p 1 validated silent c.426 p.L142 1 HMMPfam_MFS_1 HMMPfam_MFS_1;superfamily_MFS general substrate transporter - no_errors LOC728138 728138 genome.wustl.edu 36 16 14990025 14990025 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 16 14990025 14990025 C T SNP LOC728138 XM_001128282 human genbank 54_36p -1 model silent c.1419 p.A473 1 NULL - - no_errors ADCY9 115 genome.wustl.edu 36 16 3997506 3997506 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 16 3997506 3997506 C A SNP ADCY9 NM_001116 human genbank 54_36p -1 reviewed missense c.1748 p.C583F 1 NULL HMMPfam_Guanylate_cyc;superfamily_p53-like transcription factors;superfamily_Adenylyl and guanylyl cyclase catalytic domain - no_errors MYH1 4619 genome.wustl.edu 36 17 10345698 10345698 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 10345698 10345698 T C SNP MYH1 NM_005963 human genbank 54_36p -1 reviewed missense c.3286 p.S1096G 1 HMMPfam_Myosin_tail_1 HMMPfam_IQ;HMMPfam_Myosin_head;HMMPfam_Myosin_tail_1;HMMPfam_Myosin_N;superfamily_Prefoldin;superfamily_tRNA-binding arm;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors PRPF8 10594 genome.wustl.edu 36 17 1525263 1525263 + Missense_Mutation SNP C G G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C G G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 1525263 1525263 C G SNP PRPF8 NM_006445 human genbank 54_36p -1 reviewed missense c.2993 p.R998P 1 NULL HMMPfam_Mov34;superfamily_Cupredoxins;HMMPfam_PRO8NT;HMMPfam_PROCN;HMMPfam_PROCT - no_errors OR3A4 390756 genome.wustl.edu 36 17 3160859 3160859 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 3160859 3160859 C G SNP OR3A4 ENST00000323164 human ensembl 54_36p 1 known missense c.505 p.L169V 0.01 HMMPfam_7tm_1 HMMPfam_7tm_1;superfamily_Family A G protein-coupled receptor-like - no_errors KRT14 3861 genome.wustl.edu 36 17 36993338 36993338 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 36993338 36993338 C T SNP KRT14 NM_000526 human genbank 54_36p -1 reviewed silent c.1044 p.Q348 1 HMMPfam_Filament HMMPfam_Filament;superfamily_Prefoldin - no_errors EZH1 2145 genome.wustl.edu 36 17 38108443 38108443 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture Sanger_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 38108443 38108443 C T SNP EZH1 NM_001991 human genbank 54_36p -1 validated missense c.2161 p.E721K 1 NULL - - no_errors BPTF 2186 genome.wustl.edu 36 17 63351149 63351150 + Missense_Mutation DNP AG AG CC novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 AG AG AG CC AG AG Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 63351149 63351150 AG CC DNP BPTF NM_182641 human genbank 54_36p 1 reviewed missense c.5733_5734 p.V1912L 0.863:0.870 NULL HMMPfam_Bromodomain;HMMPfam_PHD;HMMPfam_DDT;superfamily_FYVE/PHD zinc finger;superfamily_WD40 repeat-like;superfamily_N-terminal domain of adenylylcyclase associated protein CAP;superfamily_Bromodomain;superfamily_TPR-like - no_errors CD300LB 124599 genome.wustl.edu 36 17 70039181 70039181 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 70039181 70039181 G C SNP CD300LB NM_174892 human genbank 54_36p -1 validated missense c.15 p.C5W NULL HMMPfam_V-set;superfamily_Immunoglobulin - no_errors CLDN7 1366 genome.wustl.edu 36 17 7104913 7104913 + Silent SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 7104913 7104913 C A SNP CLDN7 NM_001307 human genbank 54_36p -1 validated silent c.339 p.V113 0.99 HMMPfam_PMP22_Claudin HMMPfam_PMP22_Claudin - no_errors DNAH17 8632 genome.wustl.edu 36 17 73999186 73999186 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 73999186 73999186 G A SNP DNAH17 ENST00000300671 human ensembl 54_36p -1 known silent c.6588 p.I2196 0.993 NULL - - no_errors LGALS3BP 3959 genome.wustl.edu 36 17 74480227 74480227 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 74480227 74480227 C A SNP LGALS3BP NM_005567 human genbank 54_36p -1 reviewed missense c.784 p.D262Y 0.822 HMMPfam_BACK SRCR,HMMPfam_SRCR,SRCR-like,superfamily_SRCR-like,BACK,HMMPfam_BACK,POZ domain,superfamily_POZ domain - no_errors TP53 7157 genome.wustl.edu 36 17 7518990 7518990 + Missense_Mutation SNP A G G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A G G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 17 7518990 7518990 A G SNP TP53 NM_000546 human genbank 54_36p -1 reviewed missense c.584 p.I195T 1 HMMPfam_P53 superfamily_p53-like transcription factors;superfamily_p53 tetramerization domain;P53_tetramer;HMMPfam_P53_tetramer;P53;HMMPfam_P53;P53_TAD;HMMPfam_P53_TAD - no_errors GNAL 2774 genome.wustl.edu 36 18 11870995 11870995 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 18 11870995 11870995 G C SNP GNAL NM_182978 human genbank 54_36p 1 validated missense c.1238 p.S413T 1 HMMPfam_G-alpha HMMPfam_G-alpha;superfamily_Transducin (alpha subunit) insertion domain;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors DSG2 1829 genome.wustl.edu 36 18 27370347 27370347 + Missense_Mutation SNP A A T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 18 27370347 27370347 A T SNP DSG2 NM_001943 human genbank 54_36p 1 reviewed missense c.1608 p.K536N 0.96 NULL HMMPfam_Cadherin;superfamily_Cadherin-like;superfamily_dsRNA-binding domain-like - no_errors COLEC12 81035 genome.wustl.edu 36 18 336824 336824 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 18 336824 336824 C G SNP COLEC12 NM_130386 human genbank 54_36p -1 validated missense c.798 p.Q266H 1 NULL HMMPfam_Lectin_C;HMMPfam_Collagen;superfamily_C-type lectin-like - no_errors ZNF516 9658 genome.wustl.edu 36 18 72220900 72220900 + Missense_Mutation SNP C G G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C G G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 18 72220900 72220900 C G SNP ZNF516 ENST00000217537 human ensembl 54_36p -1 known missense c.2158 p.G720R NULL - - no_errors TSHZ3 57616 genome.wustl.edu 36 19 36461226 36461226 + Missense_Mutation SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 36461226 36461226 A G SNP TSHZ3 NM_020856 human genbank 54_36p -1 validated missense c.1313 p.L438P 0.98 NULL - - no_errors ZNF345 25850 genome.wustl.edu 36 19 42059828 42059828 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 42059828 42059828 G A SNP ZNF345 NM_003419 human genbank 54_36p 1 provisional missense c.256 p.G86S 1 NULL - - no_errors FCGBP 8857 genome.wustl.edu 36 19 45125384 45125384 + Missense_Mutation SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 45125384 45125384 A G SNP FCGBP NM_003890 human genbank 54_36p -1 validated missense c.725 p.L242P 1 NULL HMMPfam_VWD;HMMPfam_TIL;superfamily_Serine proterase inhibitors;HMMPfam_TIL_assoc;superfamily_Concanavalin A-like lectins/glucanases;HMMPfam_DUF1787;superfamily_EGF/Laminin - no_errors CYP2A6 1548 genome.wustl.edu 36 19 46048154 46048154 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 46048154 46048154 C T SNP CYP2A6 NM_000762 human genbank 54_36p -1 reviewed missense c.18 p.M6I 0.06 NULL - - no_errors PSG3 5671 genome.wustl.edu 36 19 47929004 47929004 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 47929004 47929004 C T SNP PSG3 NM_021016 human genbank 54_36p -1 validated missense c.481 p.D161N NULL HMMPfam_V-set;HMMPfam_ig;superfamily_Immunoglobulin - no_errors ZNF45 7596 genome.wustl.edu 36 19 49114870 49114870 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 49114870 49114870 T C SNP ZNF45 NM_003425 human genbank 54_36p -1 provisional missense c.227 p.N76S NULL HMMPfam_KRAB;HMMPfam_zf-C2H2;superfamily_KRAB domain (Kruppel-associated box Pfam 01352);superfamily_C2H2 and C2HC zinc fingers - no_errors C5AR1 728 genome.wustl.edu 36 19 52514960 52514960 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 52514960 52514960 C T SNP C5AR1 NM_001736 human genbank 54_36p 1 validated missense c.86 p.T29I NULL HMMPfam_7tm_1;superfamily_Family A G protein-coupled receptor-like - no_errors SIGLEC12 89858 genome.wustl.edu 36 19 56696534 56696534 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 56696534 56696534 G A SNP SIGLEC12 NM_053003 human genbank 54_36p -1 reviewed missense c.266 p.T89I HMMPfam_V-set HMMPfam_V-set;HMMPfam_ig;HMMPfam_C2-set_2;superfamily_Immunoglobulin - no_errors KIR2DL3 3804 genome.wustl.edu 36 19 59941855 59941855 + Silent SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 59941855 59941855 T A SNP KIR2DL3 NM_015868 human genbank 54_36p 1 reviewed silent c.33 p.V11 0 NULL HMMPfam_ig;superfamily_Immunoglobulin - no_errors KIR2DL1 3802 genome.wustl.edu 36 19 59993361 59993361 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 59993361 59993361 C G SNP KIR2DL1 ENST00000391730 human ensembl 54_36p 1 known missense c.728 p.S243C 0.74 NULL - - no_errors MZF1 7593 genome.wustl.edu 36 19 63774194 63774194 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 63774194 63774194 C T SNP MZF1 NM_003422 human genbank 54_36p -1 validated silent c.375 p.E125 0.32 HMMPfam_SCAN HMMPfam_SCAN;HMMPfam_zf-C2H2;superfamily_C2H2 and C2HC zinc fingers - no_errors C19orf45 374877 genome.wustl.edu 36 19 7476999 7476999 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 7476999 7476999 G A SNP C19orf45 NM_198534 human genbank 54_36p 1 validated silent c.1113 p.Q371 0 NULL - - no_errors C19orf45 374877 genome.wustl.edu 36 19 7477020 7477020 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 7477020 7477020 G A SNP C19orf45 NM_198534 human genbank 54_36p 1 validated silent c.1134 p.L378 0 NULL - - no_errors STXBP2 6813 genome.wustl.edu 36 19 7611910 7611910 + Silent SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 7611910 7611910 G T SNP STXBP2 ENST00000320400 human ensembl 54_36p 1 known silent c.1011 p.L337 0.07 NULL HMMPfam_Sec1;superfamily_Sec1/munc18-like (SM) proteins - no_start_codon CCDC138 165055 genome.wustl.edu 36 2 108798892 108798892 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 108798892 108798892 C G SNP CCDC138 NM_144978 human genbank 54_36p 1 provisional missense c.1105 p.H369D 1 NULL - - no_errors FAP 2191 genome.wustl.edu 36 2 162782770 162782770 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 162782770 162782770 G A SNP FAP NM_004460 human genbank 54_36p -1 reviewed missense c.734 p.P245L 1 HMMPfam_DPPIV_N HMMPfam_Peptidase_S9;HMMPfam_DPPIV_N;superfamily_alpha/beta-Hydrolases;superfamily_Dipeptidyl peptidase IV/CD26 N-terminal domain - no_errors FASTKD1 79675 genome.wustl.edu 36 2 170102046 170102046 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 170102046 170102046 C T SNP FASTKD1 NM_024622 human genbank 54_36p -1 validated missense c.2125 p.E709K 1 HMMPfam_FAST_2 HMMPfam_FAST_1;HMMPfam_FAST_2;HMMPfam_RAP - no_errors PDE11A 50940 genome.wustl.edu 36 2 178202430 178202430 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 178202430 178202430 G T SNP PDE11A NM_016953 human genbank 54_36p -1 reviewed missense c.2753 p.A918D 0.21 NULL HMMPfam_PDEase_I;HMMPfam_GAF;superfamily_HD-domain/PDEase-like;superfamily_GAF domain-like - no_errors MSGN1 343930 genome.wustl.edu 36 2 17861525 17861525 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 17861525 17861525 G A SNP MSGN1 NM_001105569 human genbank 54_36p 1 inferred missense c.259 p.A87T NULL - - no_errors TTN 7273 genome.wustl.edu 36 2 179133251 179133251 + Missense_Mutation SNP T T G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 179133251 179133251 T G SNP TTN NM_133378 human genbank 54_36p -1 reviewed missense c.78149 p.D26050A 1 NULL - - pseudogene:no_stop_codon:bad_bp_length_for_coding_region TTN 7273 genome.wustl.edu 36 2 179205590 179205590 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 179205590 179205590 G A SNP TTN NM_133378 human genbank 54_36p -1 reviewed missense c.35684 p.S11895L 1 NULL - - pseudogene:no_stop_codon:bad_bp_length_for_coding_region ALS2CR8 79800 genome.wustl.edu 36 2 203515797 203515797 + Silent SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 203515797 203515797 T C SNP ALS2CR8 NM_001104586 human genbank 54_36p 1 validated silent c.168 p.N56 0.02 NULL - - no_errors MAP2 4133 genome.wustl.edu 36 2 210267017 210267017 + Silent SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 210267017 210267017 C G SNP MAP2 NM_002374 human genbank 54_36p 1 reviewed silent c.1878 p.S626 0.85 HMMPfam_MAP2_projctn HMMPfam_Tubulin-binding;HMMPfam_MAP2_projctn - no_errors ABCA12 26154 genome.wustl.edu 36 2 215570674 215570674 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 215570674 215570674 C G SNP ABCA12 NM_173076 human genbank 54_36p -1 reviewed missense c.3284 p.R1095P 1 NULL HMMPfam_ABC_tran;superfamily_Spectrin repeat;superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors SPEG 10290 genome.wustl.edu 36 2 220017706 220017706 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 220017706 220017706 C T SNP SPEG NM_005876 human genbank 54_36p 1 validated missense c.476 p.T159M 1 NULL - - no_errors SPHKAP 80309 genome.wustl.edu 36 2 228592495 228592495 + Missense_Mutation SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 228592495 228592495 A G SNP SPHKAP NM_030623 human genbank 54_36p -1 validated missense c.1319 p.V440A NULL - - no_errors TRIP12 9320 genome.wustl.edu 36 2 230358756 230358756 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 230358756 230358756 G A SNP TRIP12 NM_004238 human genbank 54_36p -1 provisional silent c.4830 p.G1610 1 NULL HMMPfam_HECT;HMMPfam_WWE;superfamily_ARM repeat;superfamily_Hect E3 ligase catalytic domain - no_errors ALPP 250 genome.wustl.edu 36 2 232951766 232951766 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 232951766 232951766 C T SNP ALPP NM_001632 human genbank 54_36p 1 reviewed missense c.10 p.P4S 0.02 NULL HMMPfam_Alk_phosphatase;superfamily_Alkaline phosphatase-like - no_errors COL6A3 1293 genome.wustl.edu 36 2 237942408 237942408 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 237942408 237942408 C A SNP COL6A3 NM_004369 human genbank 54_36p -1 reviewed missense c.4437 p.Q1479H 1 HMMPfam_VWA VWA;HMMPfam_VWA;Kunitz_BPTI;HMMPfam_Kunitz_BPTI;Collagen;HMMPfam_Collagen - no_errors PSME4 23198 genome.wustl.edu 36 2 53975704 53975704 + Missense_Mutation SNP A A C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A C A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 53975704 53975704 A C SNP PSME4 NM_014614 human genbank 54_36p -1 validated missense c.3514 p.Y1172D 1 NULL - - no_errors ANTXR1 84168 genome.wustl.edu 36 2 69158056 69158056 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 2 69158056 69158056 G A SNP ANTXR1 NM_032208 human genbank 54_36p 1 reviewed missense c.574 p.A192T 1 NULL - - no_errors TGM3 7053 genome.wustl.edu 36 20 2268522 2268522 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 2268522 2268522 G A SNP TGM3 NM_003245 human genbank 54_36p 1 reviewed missense c.1823 p.R608Q HMMPfam_Transglut_C HMMPfam_Transglut_C;superfamily_Transglutaminase two C-terminal domains;superfamily_E set domains;superfamily_Cysteine proteinases;HMMPfam_Transglut_N;HMMPfam_Transglut_core - no_errors NXT1 29107 genome.wustl.edu 36 20 23282730 23282730 + Missense_Mutation SNP G A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G A G G G Unknown Valid Somatic Phase_III Capture 454_PCR_WGA dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 23282730 23282730 G A SNP NXT1 NM_013248 human genbank 54_36p 1 reviewed missense c.52 p.E18K 1 HMMPfam_NTF2 HMMPfam_NTF2;superfamily_NTF2-like - no_errors NINL 22981 genome.wustl.edu 36 20 25432690 25432690 + Silent SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 25432690 25432690 C A SNP NLP NM_025176 human genbank 54_36p -1 validated silent c.759 p.V253 1 NULL - - no_errors RBM12 10137 genome.wustl.edu 36 20 33705476 33705476 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 33705476 33705476 T C SNP RBM12 NM_006047 human genbank 54_36p -1 reviewed missense c.1183 p.M395V 0.94 NULL - - no_errors CTNNBL1 56259 genome.wustl.edu 36 20 35904173 35904173 + Silent SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 35904173 35904173 T C SNP CTNNBL1 NM_030877 human genbank 54_36p 1 reviewed silent c.1330 p.L444 0.97 NULL - - no_errors TOP1 7150 genome.wustl.edu 36 20 39139642 39139642 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 39139642 39139642 G T SNP TOP1 NM_003286 human genbank 54_36p 1 reviewed missense c.286 p.A96S 1 NULL Topoisom_I_N;HMMPfam_Topoisom_I_N;Eukaryotic DNA topoisomerase I dispensable insert domain;superfamily_Eukaryotic DNA topoisomerase I dispensable insert domain;DNA breaking-rejoining enzymes;superfamily_DNA breaking-rejoining enzymes;Topoisom_I;HMMPfam_Topoisom_I;Eukaryotic DNA topoisomerase I N-terminal DNA-binding fragment;superfamily_Eukaryotic DNA topoisomerase I N-terminal DNA-binding fragment - no_errors TPD52L2 7165 genome.wustl.edu 36 20 61977628 61977628 + Silent SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 20 61977628 61977628 T A SNP TPD52L2 NM_199360 human genbank 54_36p 1 validated silent c.330 p.S110 1 HMMPfam_TPD52 HMMPfam_TPD52 - no_errors DIP2A 23181 genome.wustl.edu 36 21 46748734 46748734 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 21 46748734 46748734 G A SNP DIP2A NM_015151 human genbank 54_36p 1 reviewed missense c.688 p.G230S 1 NULL - - no_errors DGCR14 8220 genome.wustl.edu 36 22 17507498 17507498 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 22 17507498 17507498 C A SNP DGCR14 NM_022719 human genbank 54_36p -1 reviewed missense c.440 p.S147I 1 NULL - - no_errors PIWIL3 440822 genome.wustl.edu 36 22 23488369 23488369 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 22 23488369 23488369 G C SNP PIWIL3 NM_001008496 human genbank 54_36p -1 validated missense c.98 p.A33G NULL HMMPfam_PAZ;HMMPfam_Piwi;superfamily_Ribonuclease H-like;superfamily_PAZ domain - no_errors FBXO7 25793 genome.wustl.edu 36 22 31211059 31211059 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 22 31211059 31211059 C T SNP FBXO7 NM_012179 human genbank 54_36p 1 reviewed missense c.650 p.T217I 0.98 NULL HMMPfam_F-box;superfamily_Ubiquitin-like;superfamily_F-box domain - no_errors LOC100128853 100128853 genome.wustl.edu 36 19 23467522 23467522 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 19 23467522 23467522 C A SNP LOC100128853 XM_001726893 human genbank 54_36p -1 model missense c.496 p.A166S NULL - - pseudogene CEP63 80254 genome.wustl.edu 36 3 135738746 135738746 + Silent SNP A A T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 3 135738746 135738746 A T SNP CEP63 NM_025180 human genbank 54_36p 1 reviewed silent c.501 p.V167 1 NULL - - no_errors STAG1 10274 genome.wustl.edu 36 3 137550738 137550738 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 3 137550738 137550738 C G SNP STAG1 NM_005862 human genbank 54_36p -1 reviewed missense c.3223 p.V1075L 1 NULL HMMPfam_STAG;superfamily_ARM repeat - no_errors LOC389168 389168 genome.wustl.edu 36 3 157188591 157188591 + RNA SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 3 157188591 157188591 G A SNP LOC389168 XR_017613 human genbank 54_36p 1 model rna NULL NULL 1 - - - pseudogene EIF2B5 8893 genome.wustl.edu 36 3 185340583 185340583 + Missense_Mutation SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 3 185340583 185340583 A G SNP EIF2B5 NM_003907 human genbank 54_36p 1 validated missense c.787 p.N263D 1 NULL HMMPfam_Hexapep;HMMPfam_W2;superfamily_Trimeric LpxA-like enzymes;superfamily_ARM repeat;superfamily_Nucleotide-diphospho-sugar transferases - no_errors LOC642892 642892 genome.wustl.edu 36 3 197747883 197747883 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 3 197747883 197747883 C T SNP LOC642892 XM_001718231 human genbank 54_36p 1 model silent c.84 p.H28 1 NULL - - pseudogene BHLHE40 8553 genome.wustl.edu 36 3 5000108 5000108 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 3 5000108 5000108 C G SNP BHLHE40 NM_003670 human genbank 54_36p 1 reviewed missense c.970 p.P324A 1 NULL HMMPfam_HLH;HMMPfam_Hairy_orange;superfamily_HLH helix-loop-helix DNA-binding domain - no_errors LOC100128525 100128525 genome.wustl.edu 36 22 38601808 38601808 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 22 38601808 38601808 G C SNP LOC100128525 XM_001716642 human genbank 54_36p 1 model missense c.532 p.V178L 1 NULL - - pseudogene FAT4 79633 genome.wustl.edu 36 4 126549081 126549081 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 126549081 126549081 G A SNP FAT4 NM_024582 human genbank 54_36p 1 validated missense c.5602 p.D1868N 1 NULL - - no_errors WWC2 80014 genome.wustl.edu 36 4 184403640 184403640 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 184403640 184403640 C T SNP WWC2 NM_024949 human genbank 54_36p 1 validated missense c.680 p.S227F 1 NULL - - no_errors FAM193A 8603 genome.wustl.edu 36 4 2668058 2668058 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 2668058 2668058 C T SNP C4orf8 NM_003704 human genbank 54_36p 1 validated silent c.2574 p.S858 0.13 NULL - - no_errors UBE2K 3093 genome.wustl.edu 36 4 39423776 39423780 + Frame_Shift_Del DEL ACCAA ACCAA - novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 ACCAA ACCAA ACCAA - ACCAA ACCAA Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 39423776 39423780 ACCAA - DEL UBE2K NM_005339 human genbank 54_36p 1 reviewed frame_shift_del c.167_171 p.Y56fs 1.000:0.998:1.000:1.000:0.991 NULL - (deletion:cds_exon[39423767;39423825]) no_errors GRXCR1 389207 genome.wustl.edu 36 4 42590045 42590045 + Missense_Mutation SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 42590045 42590045 T A SNP GRXCR1 NM_001080476 human genbank 54_36p 1 inferred missense c.5 p.L2H 0.89 NULL - - no_errors LPHN3 23284 genome.wustl.edu 36 4 62496566 62496566 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 62496566 62496566 C G SNP LPHN3 NM_015236 human genbank 54_36p 1 reviewed missense c.2578 p.L860V 0.99 NULL - - no_errors FRAS1 80144 genome.wustl.edu 36 4 79377709 79377709 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 4 79377709 79377709 G A SNP FRAS1 ENST00000380674 human ensembl 54_36p 1 known missense c.130 p.D44N 1 NULL - - no_errors PCDHA5 56143 genome.wustl.edu 36 5 140182735 140182735 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 140182735 140182735 G A SNP PCDHA5 NM_018908 human genbank 54_36p 1 reviewed silent c.1191 p.V397 0.88 NULL - - no_errors HDAC3 8841 genome.wustl.edu 36 5 140989008 140989008 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 140989008 140989008 C G SNP HDAC3 NM_003883 human genbank 54_36p -1 reviewed missense c.526 p.G176R 1 HMMPfam_Hist_deacetyl HMMPfam_Hist_deacetyl;superfamily_Arginase/deacetylase - no_errors SPRY4 81848 genome.wustl.edu 36 5 141674769 141674769 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 141674769 141674769 C A SNP SPRY4 NM_030964 human genbank 54_36p -1 validated missense c.158 p.R53L 1 NULL HMMPfam_Sprouty - no_errors PDGFRB 5159 genome.wustl.edu 36 5 149480685 149480685 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 149480685 149480685 G C SNP PDGFRB NM_002609 human genbank 54_36p -1 reviewed missense c.2545 p.R849G 1 HMMPfam_Pkinase_Tyr Pkinase_Tyr;HMMPfam_Pkinase_Tyr;ig;HMMPfam_ig - no_errors IL6ST 3572 genome.wustl.edu 36 5 55294991 55294991 + Silent SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 55294991 55294991 T A SNP IL6ST NM_002184 human genbank 54_36p -1 reviewed silent c.759 p.I253 HMMPfam_fn3 HMMPfam_fn3;superfamily_Fibronectin type III;HMMPfam_Lep_receptor_Ig - no_errors HEXB 3074 genome.wustl.edu 36 5 74050387 74050387 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 74050387 74050387 G C SNP HEXB NM_000521 human genbank 54_36p 1 reviewed missense c.1252 p.G418R 0.98 HMMPfam_Glyco_hydro_20 HMMPfam_Glyco_hydro_20b;HMMPfam_Glyco_hydro_20;superfamily_(Trans)glycosidases;superfamily_beta-N-acetylhexosaminidase-like domain - no_errors F2RL2 2151 genome.wustl.edu 36 5 75954796 75954796 + Missense_Mutation SNP A A C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A C A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 5 75954796 75954796 A C SNP F2RL2 NM_004101 human genbank 54_36p -1 reviewed missense c.16 p.F6V NULL HMMPfam_7tm_1;superfamily_Family A G protein-coupled receptor-like - no_errors SIM1 6492 genome.wustl.edu 36 6 100945522 100945522 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 100945522 100945522 C G SNP SIM1 NM_005068 human genbank 54_36p -1 reviewed missense c.1737 p.E579D 1 HMMPfam_SIM_C HMMPfam_HLH;HMMPfam_SIM_C;superfamily_HLH helix-loop-helix DNA-binding domain;HMMPfam_PAS_3;HMMPfam_PAS;superfamily_PYP-like sensor domain (PAS domain) - no_errors SYCP2L 221711 genome.wustl.edu 36 6 11006314 11006314 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 11006314 11006314 G C SNP SYCP2L NM_001040274 human genbank 54_36p 1 provisional missense c.421 p.D141H 0.97 NULL - - no_errors FRK 2444 genome.wustl.edu 36 6 116431838 116431838 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 116431838 116431838 T C SNP FRK NM_002031 human genbank 54_36p -1 reviewed missense c.361 p.I121V 1 HMMPfam_SH2 SH2;HMMPfam_SH2;Pkinase_Tyr;HMMPfam_Pkinase_Tyr;SH3_1;HMMPfam_SH3_1 - no_errors MYB 4602 genome.wustl.edu 36 6 135563199 135563199 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 135563199 135563199 G C SNP MYB NM_005375 human genbank 54_36p 1 validated missense c.1540 p.E514Q 0.96 HMMPfam_Cmyb_C superfamily_Homeodomain-like;HMMPfam_Wos2;HMMPfam_Myb_DNA-binding;HMMPfam_Cmyb_C - no_errors HIST1H2BO 8348 genome.wustl.edu 36 6 27969325 27969325 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 27969325 27969325 G A SNP HIST1H2BO NM_003527 human genbank 54_36p 1 reviewed missense c.106 p.E36K 1 NULL - - no_errors PGBD1 84547 genome.wustl.edu 36 6 28377695 28377695 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 28377695 28377695 C T SNP PGBD1 NM_032507 human genbank 54_36p 1 reviewed silent c.2085 p.I695 1 NULL - - no_errors TREML2 79865 genome.wustl.edu 36 6 41276717 41276717 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 41276717 41276717 G A SNP TREML2 NM_024807 human genbank 54_36p -1 validated missense c.185 p.P62L 0.07 NULL - - no_errors ENPP4 22875 genome.wustl.edu 36 6 46215774 46215774 + Silent SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture Sanger_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 46215774 46215774 T C SNP ENPP4 NM_014936 human genbank 54_36p 1 validated silent c.495 p.N165 0.22 HMMPfam_Phosphodiest HMMPfam_Phosphodiest;superfamily_Alkaline phosphatase-like - no_errors PKHD1 5314 genome.wustl.edu 36 6 51840792 51840792 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 51840792 51840792 C A SNP PKHD1 NM_138694 human genbank 54_36p -1 reviewed missense c.7561 p.A2521S 1 NULL HMMPfam_TIG;superfamily_Pectin lyase-like;superfamily_E set domains;superfamily_Anthrax protective antigen - no_errors PKHD1 5314 genome.wustl.edu 36 6 51990356 51990356 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic Phase_III Capture 454_PCR_WGA dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 51990356 51990356 C T SNP PKHD1 NM_138694 human genbank 54_36p -1 reviewed missense c.5411 p.R1804H NULL HMMPfam_TIG;superfamily_Pectin lyase-like;superfamily_E set domains;superfamily_Anthrax protective antigen - no_errors HMGCLL1 54511 genome.wustl.edu 36 6 55486876 55486876 + Silent SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 55486876 55486876 G T SNP HMGCLL1 NM_019036 human genbank 54_36p -1 validated silent c.561 p.S187 0.99 NULL - - no_errors DST 667 genome.wustl.edu 36 6 56577184 56577184 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 56577184 56577184 C T SNP DST NM_020388 human genbank 54_36p -1 reviewed missense c.8590 p.E2864K NULL - - no_errors MDN1 23195 genome.wustl.edu 36 6 90428566 90428566 + Silent SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 6 90428566 90428566 A G SNP MDN1 NM_014611 human genbank 54_36p -1 provisional silent c.14526 p.G4842 0.96 NULL - - no_errors LOC100130721 100130721 genome.wustl.edu 36 7 64437805 64437805 + RNA SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 64437805 64437805 C G SNP LOC100130721 XR_037257 human genbank 54_36p -1 model rna NULL NULL 1 - - - pseudogene LOC441442 441442 genome.wustl.edu 36 9 67847665 67847665 + RNA SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 9 67847665 67847665 G T SNP LOC441442 XR_037084 human genbank 54_36p -1 model rna NULL NULL 1 - - - pseudogene AZGP1P2 401393 genome.wustl.edu 36 7 100717601 100717601 + Missense_Mutation SNP A A G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A G A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 100717601 100717601 A G SNP AZGP1P2 ENST00000397935 human ensembl 54_36p -1 known missense c.220 p.W74R 0.21 NULL - - no_errors PPP1R3A 5506 genome.wustl.edu 36 7 113345820 113345820 + Missense_Mutation SNP T T A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T A T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 113345820 113345820 T A SNP PPP1R3A NM_002711 human genbank 54_36p -1 reviewed missense c.468 p.L156F 1 HMMPfam_CBM_21 HMMPfam_CBM_21 - no_errors RBM28 55131 genome.wustl.edu 36 7 127740546 127740546 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 127740546 127740546 T C SNP RBM28 NM_018077 human genbank 54_36p -1 validated missense c.2063 p.K688R 0.98 NULL - - no_errors CHRM2 1129 genome.wustl.edu 36 7 136350196 136350196 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 136350196 136350196 C G SNP CHRM2 NM_000739 human genbank 54_36p 1 reviewed missense c.44 p.T15R 0.07 NULL - - no_errors CHRM2 1129 genome.wustl.edu 36 7 136351313 136351313 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 136351313 136351313 G T SNP CHRM2 NM_000739 human genbank 54_36p 1 reviewed missense c.1161 p.R387S 1 NULL - - no_errors IGF2BP3 10643 genome.wustl.edu 36 7 23349916 23349916 + Silent SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 23349916 23349916 C T SNP IGF2BP3 NM_006547 human genbank 54_36p -1 reviewed silent c.1023 p.E341 1 HMMPfam_KH_1 HMMPfam_RRM_1;HMMPfam_KH_1;superfamily_Eukaryotic type KH-domain (KH-domain type I);superfamily_RNA-binding domain RBD - no_errors SAMD9 54809 genome.wustl.edu 36 7 92570228 92570228 + Missense_Mutation SNP C C A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 92570228 92570228 C A SNP SAMD9 NM_017654 human genbank 54_36p -1 validated missense c.3119 p.R1040L 0.96 NULL - - no_errors TRRAP 8295 genome.wustl.edu 36 7 98391707 98391707 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 7 98391707 98391707 G A SNP TRRAP NM_003496 human genbank 54_36p 1 validated silent c.5865 p.V1955 1 NULL HMMPfam_PI3_PI4_kinase;HMMPfam_FAT;superfamily_Protein kinase-like (PK-like);superfamily_ARM repeat;superfamily_Protein prenylyltransferase;superfamily_TPR-like;superfamily_TolA/TonB C-terminal domain - no_errors ENSG00000214331 0 genome.wustl.edu 36 16 72943457 72943457 + Missense_Mutation SNP T T C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T C T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 16 72943457 72943457 T C SNP ENSG00000214331 ENST00000398122 human ensembl 54_36p -1 known missense c.586 p.S196G 1 NULL - - no_stop_codon RB1CC1 9821 genome.wustl.edu 36 8 53749201 53749201 + Silent SNP A A C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A C A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 8 53749201 53749201 A C SNP RB1CC1 NM_014781 human genbank 54_36p -1 validated silent c.759 p.S253 0.01 NULL superfamily_Prefoldin;superfamily_Ubiquitin-like - no_errors ASPH 444 genome.wustl.edu 36 8 62718502 62718502 + Missense_Mutation SNP T T G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 T T T G T T Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 8 62718502 62718502 T G SNP ASPH NM_004318 human genbank 54_36p -1 validated missense c.754 p.T252P 0.41 HMMPfam_Asp-B-Hydro_N HMMPfam_Asp_Arg_Hydrox;HMMPfam_Asp-B-Hydro_N;superfamily_TPR-like;superfamily_Clavaminate synthase-like - no_errors COL15A1 1306 genome.wustl.edu 36 9 100807102 100807102 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 9 100807102 100807102 G A SNP COL15A1 NM_001855 human genbank 54_36p 1 reviewed silent c.1302 p.G434 NULL HMMPfam_Collagen;superfamily_Concanavalin A-like lectins/glucanases;HMMPfam_Endostatin;superfamily_C-type lectin-like - no_errors PTPN3 5774 genome.wustl.edu 36 9 111208622 111208622 + Missense_Mutation SNP A A C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A C A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 9 111208622 111208622 A C SNP PTPN3 NM_002829 human genbank 54_36p -1 reviewed missense c.1733 p.F578C 1 HMMPfam_PDZ HMMPfam_Y_phosphatase;HMMPfam_Band_41;HMMPfam_PDZ;superfamily_PDZ domain-like;superfamily_Second domain of FERM;superfamily_PH domain-like;superfamily_(Phosphotyrosine protein) phosphatases II;superfamily_Ubiquitin-like - no_errors UGCG 7357 genome.wustl.edu 36 9 113731768 113731768 + Silent SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 9 113731768 113731768 G A SNP UGCG NM_003358 human genbank 54_36p 1 reviewed silent c.726 p.A242 1 NULL HMMPfam_Glycos_transf_2;superfamily_Nucleotide-diphospho-sugar transferases - no_errors OR1N2 138882 genome.wustl.edu 36 9 124355406 124355406 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 9 124355406 124355406 G C SNP OR1N2 NM_001004457 human genbank 54_36p 1 provisional missense c.137 p.G46A 0.43 NULL - - no_errors KRT18P13 392371 genome.wustl.edu 36 9 99501544 99501544 + Missense_Mutation SNP C C T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 9 99501544 99501544 C T SNP KRT18P13 XM_001726959 human genbank 54_36p 1 model missense c.583 p.R195C 1 NULL - - pseudogene:no_stop_codon:bad_bp_length_for_coding_region PAK3 5063 genome.wustl.edu 36 X 110253133 110253133 + Missense_Mutation SNP G G T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G T G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 110253133 110253133 G T SNP PAK3 NM_002578 human genbank 54_36p 1 reviewed missense c.146 p.R49L 1 NULL HMMPfam_PBD;HMMPfam_Pkinase;superfamily_Protein kinase-like (PK-like);superfamily_Wiscott-Aldrich syndrome protein WASP C-terminal domain - no_errors ASB11 140456 genome.wustl.edu 36 X 15216001 15216001 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C Unknown Unknown Somatic 4 Capture 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 15216001 15216001 C G SNP ASB11 NM_080873 human genbank 54_36p -1 reviewed missense c.770 p.R257T 0.03 NULL - - no_errors G6PD 2539 genome.wustl.edu 36 X 153415852 153415852 + Missense_Mutation SNP G G A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G A G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 153415852 153415852 G A SNP G6PD NM_000402 human genbank 54_36p -1 reviewed missense c.629 p.S210F 1 NULL - - no_errors MPP1 4354 genome.wustl.edu 36 X 153665519 153665519 + Missense_Mutation SNP C C G novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C C G C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 153665519 153665519 C G SNP MPP1 NM_002436 human genbank 54_36p -1 reviewed missense c.843 p.K281N 1 NULL - - no_errors OTC 5009 genome.wustl.edu 36 X 38096920 38096920 + Missense_Mutation SNP A A T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 A A A T A A Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 38096920 38096920 A T SNP OTC NM_000531 human genbank 54_36p 1 reviewed missense c.27 p.L9F 0.99 NULL superfamily_Aspartate/ornithine carbamoyltransferase;HMMPfam_OTCace;HMMPfam_OTCace_N - no_errors HEPH 9843 genome.wustl.edu 36 X 65326359 65326359 + Missense_Mutation SNP C T T novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C T T C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 65326359 65326359 C T SNP HEPH NM_014799 human genbank 54_36p 1 reviewed missense c.116 p.A39V 1 NULL - - no_errors MAGEE1 57692 genome.wustl.edu 36 X 75566885 75566885 + Missense_Mutation SNP G G C novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 G G G C G G Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 75566885 75566885 G C SNP MAGEE1 NM_020932 human genbank 54_36p 1 validated missense c.2158 p.E720Q 0.01 NULL HMMPfam_MAGE - no_errors P2RY10 27334 genome.wustl.edu 36 X 78103370 78103370 + Missense_Mutation SNP C A A novel Unknown TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 C C A A C C Unknown Valid Somatic 4 Capture 454_PCR_WGA 1 dbGAP Illumina GAIIx 990c4b9d-608d-4b85-959c-5cc12f4e10fc 9f402e49-9fea-4c93-8a21-c15909fa5d38 X 78103370 78103370 C A SNP P2RY10 NM_014499 human genbank 54_36p 1 reviewed missense c.697 p.Q233K 0.86 HMMPfam_7tm_1 HMMPfam_7tm_1;superfamily_Family A G protein-coupled receptor-like - no_errors