Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	ACHILLES_Lineage_Results_Top_Genes	CGC_CancerGermlineMut	CGC_CancerMolecularGenetics	CGC_CancerSomaticMut	CGC_CancerSyndrome	CGC_Chr	CGC_ChrBand	CGC_GeneID	CGC_Name	CGC_OtherGermlineMut	CGC_TissueType	COSMIC_n_overlapping_mutations	COSMIC_overlapping_mutation_descriptions	ClinVar_ASSEMBLY	ClinVar_HGMD_ID	ClinVar_SYM	ClinVar_TYPE	ClinVar_rs	Ensembl_so_accession	Ensembl_so_term	Familial_Cancer_Genes_Reference	Familial_Cancer_Genes_Synonym	annotation_transcript	bcgsc	broad	build	ccds_id	dbNSFP_1000Gp1_AC	dbNSFP_1000Gp1_AF	dbNSFP_1000Gp1_AFR_AC	dbNSFP_1000Gp1_AFR_AF	dbNSFP_1000Gp1_AMR_AC	dbNSFP_1000Gp1_AMR_AF	dbNSFP_1000Gp1_ASN_AC	dbNSFP_1000Gp1_ASN_AF	dbNSFP_1000Gp1_EUR_AC	dbNSFP_1000Gp1_EUR_AF	dbNSFP_Ancestral_allele	dbNSFP_CADD_phred	dbNSFP_CADD_raw	dbNSFP_CADD_raw_rankscore	dbNSFP_ESP6500_AA_AF	dbNSFP_ESP6500_EA_AF	dbNSFP_Ensembl_geneid	dbNSFP_Ensembl_transcriptid	dbNSFP_FATHMM_pred	dbNSFP_FATHMM_rankscore	dbNSFP_FATHMM_score	dbNSFP_GERP_NR	dbNSFP_GERP_RS	dbNSFP_GERP_RS_rankscore	dbNSFP_Interpro_domain	dbNSFP_LRT_Omega	dbNSFP_LRT_converted_rankscore	dbNSFP_LRT_pred	dbNSFP_LRT_score	dbNSFP_LR_pred	dbNSFP_LR_rankscore	dbNSFP_LR_score	dbNSFP_MutationAssessor_pred	dbNSFP_MutationAssessor_rankscore	dbNSFP_MutationAssessor_score	dbNSFP_MutationTaster_converted_rankscore	dbNSFP_MutationTaster_pred	dbNSFP_MutationTaster_score	dbNSFP_Polyphen2_HDIV_pred	dbNSFP_Polyphen2_HDIV_rankscore	dbNSFP_Polyphen2_HDIV_score	dbNSFP_Polyphen2_HVAR_pred	dbNSFP_Polyphen2_HVAR_rankscore	dbNSFP_Polyphen2_HVAR_score	dbNSFP_RadialSVM_pred	dbNSFP_RadialSVM_rankscore	dbNSFP_RadialSVM_score	dbNSFP_Reliability_index	dbNSFP_SIFT_converted_rankscore	dbNSFP_SIFT_pred	dbNSFP_SIFT_score	dbNSFP_SLR_test_statistic	dbNSFP_SiPhy_29way_logOdds	dbNSFP_SiPhy_29way_logOdds_rankscore	dbNSFP_SiPhy_29way_pi	dbNSFP_UniSNP_ids	dbNSFP_Uniprot_aapos	dbNSFP_Uniprot_acc	dbNSFP_Uniprot_id	dbNSFP_aaalt	dbNSFP_aapos	dbNSFP_aapos_FATHMM	dbNSFP_aapos_SIFT	dbNSFP_aaref	dbNSFP_cds_strand	dbNSFP_codonpos	dbNSFP_folddegenerate	dbNSFP_genename	dbNSFP_hg18_pos1coor	dbNSFP_phastCons100way_vertebrate	dbNSFP_phastCons100way_vertebrate_rankscore	dbNSFP_phastCons46way_placental	dbNSFP_phastCons46way_placental_rankscore	dbNSFP_phastCons46way_primate	dbNSFP_phastCons46way_primate_rankscore	dbNSFP_phyloP100way_vertebrate	dbNSFP_phyloP100way_vertebrate_rankscore	dbNSFP_phyloP46way_placental	dbNSFP_phyloP46way_placental_rankscore	dbNSFP_phyloP46way_primate	dbNSFP_phyloP46way_primate_rankscore	dbNSFP_refcodon	entrez_gene_id	external_id_capture	gencode_transcript_name	gencode_transcript_status	gencode_transcript_tags	gencode_transcript_type	gene_type	havana_transcript	hgsc	igv_bad	ucsc	t_alt_count	t_ref_count	n_alt_count	n_ref_count	validation_judgement_rna	validation_power_rna	validation_tumor_alt_count_rna	validation_tumor_ref_count_rna	validation_normal_alt_count_rna	validation_normal_ref_count_rna	min_val_count_rna	validation_judgement_targeted	validation_power_targeted	validation_tumor_alt_count_targeted	validation_tumor_ref_count_targeted	validation_normal_alt_count_targeted	validation_normal_ref_count_targeted	min_val_count_targeted	validation_judgement_localAssembly	validation_power_localAssembly	t_alt_count_localAssembly	t_ref_count_localAssembly	n_alt_count_localAssembly	n_ref_count_localAssembly	min_val_count_localAssembly	validation_judgement_KRAS	validation_power_KRAS	t_alt_count_KRAS	t_ref_count_KRAS	n_alt_count_KRAS	n_ref_count_KRAS	min_val_count_KRAS	pon_loglike	pon_pass_loglike	localAssembly_detected	ExAC_AN	ExAC_AC	ExAC_LQ	passExAC	SCNA_NA	SCNA_NB	SCNA_q_hat	SCNA_tau	IS_SCNA	purity	ploidy	dna_fraction_in_tumor	CCF_hat	CCF_CI95_low	CCF_CI95_high	CCF_mode	CCF_mean	CCF_median	clonal	CCF_CI_low	CCF_CI_high
OR51F2	119694	broad.mit.edu	37	11	4843497	4843497	+	Missense_Mutation	SNP	T	T	G			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr11:4843497T>G	ENST00000322110.5	+	1	947	c.882T>G	c.(880-882)ttT>ttG	p.F294L	MMP26_ENST00000477339.1_Intron|MMP26_ENST00000380390.1_Intron	NM_001004753.1	NP_001004753.1	Q8NH61	O51F2_HUMAN	olfactory receptor, family 51, subfamily F, member 2			33		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.0778)			CCAATGTCTTTCTGCTAATCC	0.423000																								0							SO:0001583	missense			ENST00000322110.5	1	1	hg19	CCDS31361.1	.	.	.	.	.	.	.	.	.	.	T	15.120000	2.739947	0.490450	.	.	ENSG00000176925	ENST00000322110	T	0.00036	8.86	4.710000	3.790000	0.435880	GPCR, rhodopsin-like superfamily (1);	1.791850e-01	0.266840	U	2.303100e-02	T	0.00210	0.0006	L	0.48642	1.525	0.093100	N	0.999996	P	0.43287	0.802	P	0.47251	0.542	T	0.46527	-0.9185	10	0.87932	D	0	.	11.197800	0.487240	0.0:0.907:0.0:0.093	.	294	Q8NH61	O51F2_HUMAN	L	294	ENSP00000323952:F294L	ENSP00000323952:F294L	F	+	3	2	OR51F2	4800073	0	0.058580	9.280000e-01	0.369950	6.190000e-01	0.375520	-0.058000	0.117500	1.312000	0.450430	-0.366000	0.074230	TTT		TCGA-HZ-7925-01A-11D-2154-08	OR51F2-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000142181.1	1	0	0	22	457	0	69		0	0	0	0	69	2		0	0	0	0	0	2	1	0.999999	22	446	0	68	2		0	0	0	0	69	2	-4.911525	1	1	0	0		1	0	1	1	2.018944	0	0.240000	1.910000	0.238172	0.380000	0.240000	0.550000	0.380000	0.394870	0.380000	0	0.300000	0.470000
NAALAD2	10003	broad.mit.edu	37	11	89891358	89891358	+	Missense_Mutation	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr11:89891358G>A	ENST00000534061.1	+	7	1072	c.842G>A	c.(841-843)cGa>cAa	p.R281Q	NAALAD2_ENST00000375944.3_Intron|NAALAD2_ENST00000321955.4_Missense_Mutation_p.R281Q|NAALAD2_ENST00000525171.1_Intron	NM_005467.3	NP_005458.1	Q9Y3Q0	NALD2_HUMAN	N-acetylated alpha-linked acidic dipeptidase 2			59		Acute lymphoblastic leukemia(157;2.31e-05)|all_hematologic(158;0.00556)			GGAATCCCCCGAATACCTGTA	0.313000																								0							SO:0001583	missense			ENST00000534061.1	1	1	hg19	CCDS8288.1	.	.	.	.	.	.	.	.	.	.	G	13.600000	2.285494	0.403940	.	.	ENSG00000077616	ENST00000534061;ENST00000321955	T;T	0.41758	0.99;0.99	5.130000	3.990000	0.463010	.	7.974990e-01	0.117310	N	5.349860e-01	T	0.21801	0.0525	N	0.05414	-0.055	0.807220	D	1.000000	B;B	0.02656	0.0;0.0	B;B	0.01281	0.0;0.0	T	0.05084	-1.0907	9	.	.	.	0.2934	8.417500	0.326810	0.8469:0.0:0.1531:0.0	.	281;281	Q9Y3Q0;Q8IUX3	NALD2_HUMAN;.	Q	281	ENSP00000432481:R281Q;ENSP00000320083:R281Q	.	R	+	2	0	NAALAD2	89531006	9.680000e-01	0.334300	4.430000e-01	0.268830	9.820000e-01	0.717510	3.300000	0.518340	0.919000	0.369450	-0.341000	0.080070	CGA		TCGA-HZ-7925-01A-11D-2154-08	NAALAD2-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000389424.2	1	0	1	62	541	0	163	0	8.828288e-02	0	5	0	163	2		0	0	0	0	0	2	1	1.000000	62	531	0	161	2		0	0	0	0	163	2	-18.681520	1	1	121404	2	41	1	0	1	1	2.013716	0	0.240000	1.910000	0.236334	0.840000	0.660000	1.000000	1.000000	0.854274	0.840000	0	0.750000	0.960000
GIT2	9815	broad.mit.edu	37	12	110397662	110397662	+	Silent	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08			C	T	C	C		Valid	Somatic	Phase_I	WXS	RNA			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr12:110397662C>T	ENST00000355312.3	-	12	1088	c.1089G>A	c.(1087-1089)tcG>tcA	p.S363S	GIT2_ENST00000551209.1_Silent_p.S362S|TCHP_ENST00000550780.1_Intron|GIT2_ENST00000356259.4_Silent_p.S363S|GIT2_ENST00000338373.5_Silent_p.S363S|GIT2_ENST00000360185.4_Silent_p.S363S|GIT2_ENST00000343646.5_Intron|GIT2_ENST00000354574.4_Silent_p.S365S|GIT2_ENST00000553118.1_Silent_p.S363S|GIT2_ENST00000547815.1_Silent_p.S363S|GIT2_ENST00000320063.9_Silent_p.S363S|GIT2_ENST00000361006.5_Silent_p.S363S|GIT2_ENST00000457474.2_Silent_p.S365S	NM_057169.3	NP_476510.1	Q14161	GIT2_HUMAN	G protein-coupled receptor kinase interacting ArfGAP 2			27					CTTTTGAACCCGAGAGAGAAC	0.453000																								0							SO:0001819	synonymous_variant			ENST00000355312.3	1	0	hg19	CCDS9138.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	GIT2-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000403407.1	1	0	0	17	164	0	41	1	9.923169e-01	10	69	0	41	2		0	0	0	0	0	2	1	0.999969	15	163	0	40	2		0	0	0	0	41	2	-2.716771	1	1	0	0		1	0	0	0	1.991019	0	0.240000	1.910000	0.227014	0.770000	0.470000	1.000000	1.000000	0.778179	0.770000	0	0.610000	0.960000
KRAS	3845	broad.mit.edu	37	12	25398284	25398284	+	Missense_Mutation	SNP	C	C	A	rs121913529		TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08			C	A	C	C		Valid	Somatic	Phase_I	WXS	KRAS_deep			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr12:25398284C>A	ENST00000256078.4	-	2	98	c.35G>T	c.(34-36)gGt>gTt	p.G12V	KRAS_ENST00000556131.1_Missense_Mutation_p.G12V|KRAS_ENST00000557334.1_Missense_Mutation_p.G12V|KRAS_ENST00000311936.3_Missense_Mutation_p.G12V	NM_033360.2	NP_203524.1	P01116	RASK_HUMAN	Kirsten rat sarcoma viral oncogene homolog	p.G12D(8562)|p.G12V(5775)|p.G12A(1407)|p.G12F(46)|p.G12L(8)|p.G12I(4)|p.G12E(3)|p.G12W(3)|p.G12Y(2)|p.G12fs*3(1)|p.G12C(1)|p.G12N(1)	UBE2L3/KRAS(2)	25349	all_cancers(2;1e-35)|all_epithelial(2;1.97e-38)|all_lung(3;2.1e-23)|Lung NSC(3;1.16e-22)|Acute lymphoblastic leukemia(6;0.00231)|all_hematologic(7;0.00259)|Melanoma(3;0.0301)|Colorectal(261;0.11)|Ovarian(17;0.12)		OV - Ovarian serous cystadenocarcinoma(3;1.23e-21)|Epithelial(3;1.31e-20)|all cancers(3;5.45e-18)|STAD - Stomach adenocarcinoma(2;2.68e-05)		GCCTACGCCACCAGCTCCAAC	0.348000	G12A(KMS28BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(KPNSI9S_AUTONOMIC_GANGLIA)|G12A(MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(NCIH1573_LUNG)|G12A(NCIH2009_LUNG)|G12A(RERFLCAD1_LUNG)|G12A(RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(SW1116_LARGE_INTESTINE)|G12D(AGS_STOMACH)|G12D(ASPC1_PANCREAS)|G12D(COLO678_LARGE_INTESTINE)|G12D(HEC1A_ENDOMETRIUM)|G12D(HEC50B_ENDOMETRIUM)|G12D(HEYA8_OVARY)|G12D(HPAC_PANCREAS)|G12D(HPAFII_PANCREAS)|G12D(KARPAS620_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12D(KOPN8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12D(KP4_PANCREAS)|G12D(L33_PANCREAS)|G12D(LS180_LARGE_INTESTINE)|G12D(LS513_LARGE_INTESTINE)|G12D(MCAS_OVARY)|G12D(PANC0203_PANCREAS)|G12D(PANC0403_PANCREAS)|G12D(PANC0504_PANCREAS)|G12D(PANC0813_PANCREAS)|G12D(PANC1_PANCREAS)|G12D(PK1_PANCREAS)|G12D(PK59_PANCREAS)|G12D(SKLU1_LUNG)|G12D(SNUC2A_LARGE_INTESTINE)|G12D(SU8686_PANCREAS)|G12D(SUIT2_PANCREAS)|G12D(SW1990_PANCREAS)|G12V(A498_KIDNEY)|G12V(CAPAN2_PANCREAS)|G12V(CFPAC1_PANCREAS)|G12V(COLO668_LUNG)|G12V(CORL23_LUNG)|G12V(DANG_PANCREAS)|G12V(HCC56_LARGE_INTESTINE)|G12V(HUPT4_PANCREAS)|G12V(KP3_PANCREAS)|G12V(LCLC97TM1_LUNG)|G12V(NCIH2444_LUNG)|G12V(NCIH441_LUNG)|G12V(NCIH727_LUNG)|G12V(PANC0327_PANCREAS)|G12V(PATU8902_PANCREAS)|G12V(PATU8988S_PANCREAS)|G12V(QGP1_PANCREAS)|G12V(RCM1_LARGE_INTESTINE)|G12V(RERFLCAD2_LUNG)|G12V(RKN_OVARY)|G12V(SH10TC_STOMACH)|G12V(SHP77_LUNG)|G12V(SNGM_ENDOMETRIUM)|G12V(SW403_LARGE_INTESTINE)|G12V(SW480_LARGE_INTESTINE)|G12V(SW620_LARGE_INTESTINE)|G12V(SW900_LUNG)|G12V(YAPC_PANCREAS)	119	Mis		pancreatic, colorectal, lung, thyroid, AML, others				Noonan syndrome;Cardiofaciocutaneous syndrome	TSP Lung(1;<1E-08)|Multiple Myeloma(2;<1E-6)			Pancreas(8;6 143 191 305 2070 2426 4376 10944 11745 26467 38091 50869)		Dom	yes		12	12p12.1	3845	v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog		L, E, M, O	15813	Substitution - Missense(15812)|Deletion - Frameshift(1)						SO:0001583	missense	Familial Cancer Database	Male Turner syndrome, Pterygium Colli syndrome, incl. Noonan-like/Multiple Giant Cell Lesion syndrome; Noonan s. with multiple lentigines/LEOPARD syndrome;CFC, CFCS	ENST00000256078.4	1	1	hg19	CCDS8703.1	.	.	.	.	.	.	.	.	.	.	C	27.200000	4.808637	0.907070	.	.	ENSG00000133703	ENST00000311936;ENST00000557334;ENST00000256078;ENST00000556131	T;T;T;T	0.78707	-1.2;-1.2;-1.2;-1.2	5.680000	5.680000	0.881260	Small GTP-binding protein domain (1);	0	0.856820	D	0	D	0.90373	0.6987	M	0.90650	3.135	0.807220	D	1.000000	D;D	0.76494	0.997;0.999	D;D	0.72625	0.969;0.978	D	0.91773	0.5429	10	0.72032	D	0.01	.	18.371900	0.904090	0.0:1.0:0.0:0.0	.	12;12	P01116-2;P01116	.;RASK_HUMAN	V	12	ENSP00000308495:G12V;ENSP00000452512:G12V;ENSP00000256078:G12V;ENSP00000451856:G12V	ENSP00000256078:G12V	G	-	2	0	KRAS	25289551	1	0.714170	1	0.803570	9.980000e-01	0.957120	7.743000	0.850200	2.668000	0.907890	0.563000	0.778840	GGT		TCGA-HZ-7925-01A-11D-2154-08	KRAS-004	KNOWN	not_organism_supported|basic|appris_candidate_longest|CCDS	protein_coding	protein_coding	OTTHUMT00000412232.1	1	0	1	14	113	0	28	1	8.728364e-01	8	24	0	28	2	1	1	44	543	0	321	2	1	0.999812	14	113	0	28	2	1	1	910	7111	0	28	2	-8.430733	1	1	0	0		1	0	0	0	2.003904	0	0.240000	1.910000	0.230769	0.900000	0.530000	1.000000	1.000000	0.871138	0.900000	1	0.700000	1.000000
CTSG	1511	broad.mit.edu	37	14	25043947	25043947	+	Silent	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr14:25043947C>T	ENST00000216336.2	-	3	309	c.273G>A	c.(271-273)gcG>gcA	p.A91A		NM_001911.2	NP_001902.1	P08311	CATG_HUMAN	cathepsin G	p.A91A(1)		25					TGGCTCTGCGCGCAGTGATGT	0.532000																								1	Substitution - coding silent(1)						SO:0001819	synonymous_variant			ENST00000216336.2	1	1	hg19	CCDS9631.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	CTSG-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000276536.2	1	0	1	103	365	0	82	0	1.258312e-01	0	3	0	82	2		0	0	0	0	0	2	1	1.000000	101	356	0	82	2		0	0	0	0	82	2	-20.000000	1	1	0	0		1	0	2	2	2.022990	1	0.240000	1.910000	0.240000	0.990000	0.990000	1.000000	1.000000	1.000000	0.990000	1	0.990000	1.000000
TLN2	83660	broad.mit.edu	37	15	62993388	62993388	+	Silent	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr15:62993388G>A	ENST00000561311.1	+	16	1901	c.1671G>A	c.(1669-1671)acG>acA	p.T557T	TLN2_ENST00000306829.6_Silent_p.T557T			Q9Y4G6	TLN2_HUMAN	talin 2			99					CGGCCGGAACGGCTTCAGTTG	0.418000																								0							SO:0001819	synonymous_variant			ENST00000561311.1	1	1	hg19	CCDS32261.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	TLN2-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000257878.2	1	0	1	38	220	0	33	0	8.833369e-01	1	23	0	33	2		0	0	0	0	0	2	1	1.000000	38	216	0	33	2		0	0	0	0	33	2	-2.928209	1	1	121412	1	31	1	0	1	1	2.013467	0	0.240000	1.910000	0.236334	0.990000	0.890000	1.000000	1.000000	0.992841	0.990000	1	0.990000	1.000000
RASGRF1	5923	broad.mit.edu	37	15	79296394	79296394	+	Silent	SNP	C	C	T	rs140968213		TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr15:79296394C>T	ENST00000419573.3	-	16	2521	c.2247G>A	c.(2245-2247)tcG>tcA	p.S749S	RASGRF1_ENST00000394745.3_5'UTR|RASGRF1_ENST00000558480.2_Silent_p.S733S|RASGRF1_ENST00000560334.1_5'UTR	NM_002891.4	NP_002882.3	Q13972	RGRF1_HUMAN	Ras protein-specific guanine nucleotide-releasing factor 1			71					GGCTCGGTGACGATGTCTTGG	0.637000																								0							SO:0001819	synonymous_variant			ENST00000419573.3	1	1	hg19	CCDS10309.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	RASGRF1-001	KNOWN	basic|CCDS	protein_coding	protein_coding	OTTHUMT00000291371.3	1	0	1	52	431	0	63	1	6.235409e-02	2	2	0	63	2		0	0	0	0	0	2	1	1.000000	51	414	0	61	2		0	0	0	0	63	2	-17.981250	1	1	121406	4	38	1	0	0	0	2.004604	0	0.240000	1.910000	0.230769	0.880000	0.670000	1.000000	1.000000	0.881314	0.880000	1	0.770000	1.000000
CENPT	80152	broad.mit.edu	37	16	67863789	67863789	+	Silent	SNP	G	G	C			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08			G	C	G	G		Valid	Somatic	Phase_I	WXS	RNA			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr16:67863789G>C	ENST00000562787.1	-	12	1613	c.1065C>G	c.(1063-1065)ccC>ccG	p.P355P	CENPT_ENST00000564817.1_Intron|CENPT_ENST00000219172.3_Silent_p.P355P|CENPT_ENST00000440851.2_Silent_p.P355P|CENPT_ENST00000562947.1_5'Flank	NM_025082.3	NP_079358.3	Q96BT3	CENPT_HUMAN	centromere protein T	p.P355P(1)		10		Acute lymphoblastic leukemia(13;0.000299)|all_hematologic(13;0.0184)|Ovarian(137;0.0563)			CTACCCTGCTGGGTCCTTGTG	0.547000																								1	Substitution - coding silent(1)						SO:0001819	synonymous_variant			ENST00000562787.1	1	1	hg19	CCDS42182.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	CENPT-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000422020.1	1	0	0	159	1070	0	226	1	9.997085e-01	14	65	0	226	2		0	0	0	0	0	2	1	1.000000	153	1019	0	225	2		0	0	0	0	226	2	-2.489490	0	1	0	0		1	0	1	1	2.011944	0	0.240000	1.910000	0.236334	0.990000	0.910000	1.000000	1.000000	0.993040	0.990000	1	0.990000	1.000000
MPO	4353	broad.mit.edu	37	17	56356676	56356676	+	Silent	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr17:56356676G>A	ENST00000225275.3	-	5	836	c.660C>T	c.(658-660)aaC>aaT	p.N220N	MPO_ENST00000578493.1_5'Flank|MPO_ENST00000340482.3_Silent_p.N252N	NM_000250.1	NP_000241.1	P05164	PERM_HUMAN	myeloperoxidase			46				Aminosalicylic Acid(DB00233)|Bivalirudin(DB00006)|Calcipotriol(DB02300)|Carboplatin(DB00958)|Cefaclor(DB00833)|Cefdinir(DB00535)|Cisplatin(DB00515)|Cysteamine(DB00847)|Dapsone(DB00250)|Enoxaparin(DB01225)|Human Serum Albumin(DB00062)|L-Carnitine(DB00583)|Melatonin(DB01065)|Mesalazine(DB00244)|Nabumetone(DB00461)|Octreotide(DB00104)|Oxaliplatin(DB00526)|Propylthiouracil(DB00550)|Ticlopidine(DB00208)|Tolmetin(DB00500)	CCGGGAAGCCGTTGCGCTTGA	0.731000																								0							SO:0001819	synonymous_variant			ENST00000225275.3	0	1	hg19	CCDS11604.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	MPO-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000443971.1	1	0	0	9	43	0	8		0	0	0	0	8	2		0	0	0	0	0	2	1	0.995200	9	42	0	8	2		0	0	0	0	8	2	-18.299640	1	1	117530	2	26	1	0	1	1	2.016521	0	0.240000	1.910000	0.238172	0.990000	0.720000	1.000000	1.000000	0.978085	0.990000	1	0.990000	1.000000
TP53	7157	broad.mit.edu	37	17	7578525	7578525	+	Nonsense_Mutation	SNP	G	G	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08			G	T	G	G		Valid	Somatic	Phase_I	WXS	targeted			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr17:7578525G>T	ENST00000269305.4	-	5	594	c.405C>A	c.(403-405)tgC>tgA	p.C135*	TP53_ENST00000445888.2_Nonsense_Mutation_p.C135*|TP53_ENST00000574684.1_5'Flank|TP53_ENST00000455263.2_Nonsense_Mutation_p.C135*|TP53_ENST00000420246.2_Nonsense_Mutation_p.C135*|TP53_ENST00000359597.4_Nonsense_Mutation_p.C135*|TP53_ENST00000413465.2_Nonsense_Mutation_p.C135*	NM_000546.5|NM_001126112.2|NM_001126118.1|NM_001276760.1|NM_001276761.1	NP_000537.3|NP_001119584.1|NP_001119590.1|NP_001263689.1|NP_001263690.1	P04637	P53_HUMAN	tumor protein p53	p.C135W(24)|p.0?(8)|p.C135*(7)|p.C135C(5)|p.C135fs*9(3)|p.N131fs*27(2)|p.Q136fs*13(2)|p.F134_T140>S(1)|p.K132_A138delKMFCQLA(1)|p.S127_Q136del10(1)|p.C135T(1)|p.V73fs*9(1)|p.C135fs*15(1)|p.C135fs*14(1)|p.Y126fs*11(1)|p.C3fs*9(1)|p.C42fs*9(1)|p.C135_A138delCQLA(1)|p.C3W(1)|p.C42W(1)|p.C135_T140delCQLAKT(1)|p.Q136*(1)|p.C135_Q136insXXXXXX(1)|p.C135_Q136insX(1)		24185		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		Acetylsalicylic acid(DB00945)	TGGCCAGTTGGCAAAACATCT	0.567000		111	Mis, N, F		breast, colorectal, lung, sarcoma, adrenocortical, glioma, multiple other tumour types	breast, sarcoma, adrenocortical carcinoma, glioma, multiple other tumour types		Other conserved DNA damage response genes	Osteosarcoma, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Breast-Ovarian Cancer, non-BRCA1/2;Hereditary Adrenocortical Cancer;Endometrial Cancer, Familial Clustering of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			Pancreas(47;798 1329 9957 10801)	yes	Rec	yes	Li-Fraumeni syndrome	17	17p13	7157	tumor protein p53		L, E, M, O	68	Substitution - Missense(27)|Deletion - Frameshift(9)|Substitution - Nonsense(8)|Whole gene deletion(8)|Substitution - coding silent(5)|Deletion - In frame(4)|Insertion - Frameshift(4)|Insertion - In frame(2)|Complex - deletion inframe(1)						SO:0001587	stop_gained	Familial Cancer Database	Familial Osteogenic Sarcoma;LFS, SBLA syndrome (Sarcoma Breast Leukemia Adrenal cancer), incl.: Cancer with In Vitro Radioresistence, Familial, Li-Fraumeni-like s.;BRCAX;Familial Adrenocortical Carcinoma;	ENST00000269305.4	0	1	hg19	CCDS11118.1	.	.	.	.	.	.	.	.	.	.	G	25.800000	4.678815	0.885420	.	.	ENSG00000141510	ENST00000413465;ENST00000359597;ENST00000269305;ENST00000455263;ENST00000420246;ENST00000445888;ENST00000396473;ENST00000545858;ENST00000509690;ENST00000514944;ENST00000414315;ENST00000508793	.	.	.	5.480000	3.500000	0.400720	.	0	0.856820	D	0	.	.	.	.	.	.	0.807220	A	1.000000	.	.	.	.	.	.	.	.	.	.	0.02654	T	1	-26.815	10.022200	0.420510	0.1647:0.0:0.8353:0.0	.	.	.	.	X	135;135;135;135;135;135;124;42;3;42;3;135	.	ENSP00000269305:C135X	C	-	3	2	TP53	7519250	1	0.714170	1	0.803570	7.860000e-01	0.444420	0.645000	0.247820	0.798000	0.339940	0.655000	0.942530	TGC		TCGA-HZ-7925-01A-11D-2154-08	TP53-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000367397.1	1	0	1	24	174	0	40	1	9.996896e-01	3	93	0	40	2	1	1	272	1747	0	1456	2	1	1.000000	23	166	0	40	2		0	0	0	0	40	2	-20.000000	1	1	0	0		1	0	1	1	1.772918	1	0.240000	1.910000	0.136364	0.820000	0.570000	0.990000	0.860000	0.819381	0.820000	0	0.690000	0.940000
SYT3	84258	broad.mit.edu	37	19	51133283	51133283	+	Silent	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr19:51133283G>A	ENST00000338916.4	-	3	1453	c.820C>T	c.(820-822)Ctg>Ttg	p.L274L	SYT3_ENST00000593901.1_Silent_p.L274L|SYT3_ENST00000600079.1_Silent_p.L274L|SYT3_ENST00000544769.1_Silent_p.L274L	NM_032298.2	NP_115674.1	Q9BQG1	SYT3_HUMAN	synaptotagmin III			35		all_neural(266;0.131)			CCCTGGTACAGCTCTGGCTTA	0.677000																								0							SO:0001819	synonymous_variant			ENST00000338916.4	1	1	hg19	CCDS12798.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	SYT3-003	KNOWN	alternative_5_UTR|basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000464910.1	1	0	1	81	556	0	94		0	0	0	0	94	2		0	0	0	0	0	2	1	1.000000	80	545	0	94	2		0	0	0	0	94	2	-3.221884	1	1	0	0		1	1	2	3	2.035257	0	0.240000	1.910000	0.244533	0.990000	0.850000	1.000000	1.000000	0.983849	0.990000	1	0.950000	1.000000
ZC3H11A	9877	broad.mit.edu	37	1	203798664	203798664	+	Missense_Mutation	SNP	G	G	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08			G	T	G	G		Valid	Somatic	Phase_I	WXS	RNA			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr1:203798664G>T	ENST00000545588.1	+	5	4211	c.384G>T	c.(382-384)caG>caT	p.Q128H	ZC3H11A_ENST00000332127.4_Missense_Mutation_p.Q128H|ZC3H11A_ENST00000367212.3_Missense_Mutation_p.Q128H|ZC3H11A_ENST00000367210.1_Missense_Mutation_p.Q128H|ZC3H11A_ENST00000367214.1_Missense_Mutation_p.Q128H	NM_001271675.1	NP_001258604.1	O75152	ZC11A_HUMAN	zinc finger CCCH-type containing 11A			32	all_cancers(21;0.0904)|all_epithelial(62;0.234)		BRCA - Breast invasive adenocarcinoma(75;0.109)		TGTCTGTCCAGTCCAATCCTT	0.478000																								0							SO:0001583	missense			ENST00000545588.1	0	1	hg19	CCDS30978.1	.	.	.	.	.	.	.	.	.	.	G	27.300000	4.819026	0.908730	.	.	ENSG00000058673	ENST00000453771;ENST00000367214;ENST00000537080;ENST00000367212;ENST00000332127;ENST00000545588;ENST00000367210	T;T;T;T;T	0.50001	0.76;0.76;0.76;0.76;0.76	5.870000	5.870000	0.943060	.	2.385430e-01	0.434160	D	5.630000e-04	T	0.65460	0.2693	L	0.55481	1.735	0.477370	D	0.999509	D	0.89917	1.0	D	0.78314	0.991	T	0.63800	-0.6555	10	0.59425	D	0.04	-26.9465	17.496900	0.877200	0.0:0.0:1.0:0.0	.	128	O75152	ZC11A_HUMAN	H	128;128;74;128;128;128;128	ENSP00000356183:Q128H;ENSP00000356181:Q128H;ENSP00000333253:Q128H;ENSP00000438527:Q128H;ENSP00000356179:Q128H	ENSP00000333253:Q128H	Q	+	3	2	ZC3H11A	202065287	1	0.714170	1	0.803570	9.930000e-01	0.825480	1.089000	0.308900	2.941000	0.997820	0.655000	0.942530	CAG		TCGA-HZ-7925-01A-11D-2154-08	ZC3H11A-201	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000087471.3	1	0	0	53	523	0	94	1	9.992557e-01	17	89	0	94	2		0	0	0	0	0	2	1	1.000000	51	448	0	102	2		0	0	0	0	94	2	-20.000000	1	1	0	0		1	1	2	3	2.262092	1	0.240000	1.910000	0.320701	0.850000	0.650000	1.000000	1.000000	0.860131	0.850000	1	0.750000	0.980000
KCNH1	3756	broad.mit.edu	37	1	211256132	211256132	+	Missense_Mutation	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr1:211256132C>T	ENST00000271751.4	-	5	575	c.548G>A	c.(547-549)cGc>cAc	p.R183H	KCNH1_ENST00000367007.4_Missense_Mutation_p.R183H			O95259	KCNH1_HUMAN	potassium voltage-gated channel, subfamily H (eag-related), member 1			68					CTCTGCCAGGCGGGAGTGCTT	0.547000																								0							SO:0001583	missense			ENST00000271751.4	1	1	hg19	CCDS1496.1	.	.	.	.	.	.	.	.	.	.	C	18.170000	3.564274	0.656510	.	.	ENSG00000143473	ENST00000271751;ENST00000367007	D;D	0.98958	-5.21;-5.27	4.970000	4.970000	0.658230	.	0	0.856820	D	0	D	0.96806	0.8957	L	0.41710	1.295	0.807220	D	1.000000	B;B	0.15141	0.008;0.012	B;B	0.14023	0.006;0.01	D	0.94651	0.7839	10	0.39692	T	0.17	.	17.624300	0.880900	0.0:1.0:0.0:0.0	.	183;183	Q14CL3;O95259	.;KCNH1_HUMAN	H	183	ENSP00000271751:R183H;ENSP00000355974:R183H	ENSP00000271751:R183H	R	-	2	0	KCNH1	209322755	1	0.714170	1	0.803570	9.860000e-01	0.746190	7.383000	0.797410	2.477000	0.836380	0.561000	0.740990	CGC		TCGA-HZ-7925-01A-11D-2154-08	KCNH1-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000088332.1	1	0	1	148	501	0	98		0	0	0	0	98	2		0	0	0	0	0	2	1	1.000000	145	491	0	97	2		0	0	0	0	98	2	-20.000000	1	1	121412	1	31	1	1	2	3	2.262092	1	0.240000	1.910000	0.320701	0.990000	0.990000	1.000000	1.000000	1.000000	0.990000	1	0.990000	1.000000
USH2A	7399	broad.mit.edu	37	1	216498693	216498693	+	Missense_Mutation	SNP	T	T	C			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr1:216498693T>C	ENST00000307340.3	-	6	1483	c.1097A>G	c.(1096-1098)aAt>aGt	p.N366S	USH2A_ENST00000366943.2_Missense_Mutation_p.N366S|USH2A_ENST00000366942.3_Missense_Mutation_p.N366S	NM_206933.2	NP_996816	O75445	USH2A_HUMAN	Usher syndrome 2A (autosomal recessive, mild)			527					CACTCCTTGATTAAGCTGTGT	0.363000										HNSCC(13;0.011)														0							SO:0001583	missense			ENST00000307340.3	1	1	hg19	CCDS31025.1	.	.	.	.	.	.	.	.	.	.	T	9.139000	1.013265	0.192770	.	.	ENSG00000042781	ENST00000307340;ENST00000366943;ENST00000366942	T;T;T	0.19806	2.55;2.54;2.12	5.360000	4.230000	0.500190	Laminin, N-terminal (3);	9.635310e-01	0.084810	N	9.395880e-01	T	0.19485	0.0468	L	0.45228	1.405	0.093100	N	1.000000	B;B	0.11235	0.004;0.001	B;B	0.08055	0.003;0.002	T	0.35773	-0.9775	10	0.15066	T	0.55	.	11.093800	0.481320	0.0:0.0725:0.0:0.9275	.	366;366	O75445-2;O75445	.;USH2A_HUMAN	S	366	ENSP00000305941:N366S;ENSP00000355910:N366S;ENSP00000355909:N366S	ENSP00000305941:N366S	N	-	2	0	USH2A	214565316	2.220000e-01	0.236520	4.000000e-02	0.184470	8.770000e-01	0.505400	3.185000	0.509340	0.880000	0.359690	0.528000	0.532280	AAT		TCGA-HZ-7925-01A-11D-2154-08	USH2A-002	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000128138.1	1	0	1	48	394	0	69		0	0	0	0	69	2		0	0	0	0	0	2	1	1.000000	48	383	0	69	2		0	0	0	0	69	2	-20.000000	1	1	0	0		1	1	2	3	2.262092	1	0.240000	1.910000	0.320701	0.990000	0.760000	1.000000	1.000000	0.956424	0.990000	1	0.880000	1.000000
DISC1	27185	broad.mit.edu	37	1	231830345	231830345	+	Missense_Mutation	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr1:231830345G>A	ENST00000602281.1	+	2	894	c.841G>A	c.(841-843)Gca>Aca	p.A281T	TSNAX-DISC1_ENST00000602962.1_3'UTR|DISC1_ENST00000366637.3_5'UTR|DISC1_ENST00000366633.3_Missense_Mutation_p.A281T|DISC1_ENST00000537876.1_Missense_Mutation_p.A281T|DISC1_ENST00000317586.4_Missense_Mutation_p.A281T|DISC1_ENST00000602873.1_Intron|DISC1_ENST00000439617.2_Missense_Mutation_p.A281T|DISC1_ENST00000539444.1_Missense_Mutation_p.A281T|DISC1_ENST00000535983.1_Missense_Mutation_p.A281T|DISC1_ENST00000366636.4_Missense_Mutation_p.A281T	NM_001164542.1|NM_001164544.1	NP_001158014.1|NP_001158016.1	Q9NRI5	DISC1_HUMAN	disrupted in schizophrenia 1			15		all_cancers(173;0.0208)|Prostate(94;0.0975)			GGCCCAGGCCGCAAGGAACAG	0.612000																								0							SO:0001583	missense			ENST00000602281.1	1	1	hg19	CCDS59205.1	.	.	.	.	.	.	.	.	.	.	G	0.711000	-0.786971	0.029070	.	.	ENSG00000162946	ENST00000439617;ENST00000366637;ENST00000317586;ENST00000366636;ENST00000366638;ENST00000532576;ENST00000535983;ENST00000537876;ENST00000366633;ENST00000539444;ENST00000295051;ENST00000535944;ENST00000366632	T;T;T;T;T;T;T;T;T	0.14144	3.16;2.53;2.99;2.98;2.79;3.17;2.8;2.8;2.78	4.640000	-6.620000	0.018130	.	9.051770e-01	0.096990	N	7.673120e-01	T	0.02156	0.0067	N	0.01438	-0.865	0.093100	N	1.000000	B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B	0.28880	0.001;0.089;0.089;0.226;0.033;0.041;0.089;0.089;0.033;0.089;0.001;0.093;0.013;0.089;0.015;0.093;0.093;0.015;0.093;0.093;0.001	B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B;B	0.16722	0.001;0.009;0.013;0.013;0.005;0.016;0.009;0.009;0.005;0.009;0.001;0.008;0.005;0.009;0.005;0.005;0.008;0.005;0.005;0.005;0.003	T	0.34403	-0.9830	10	0.02654	T	1	-0.1398	1.060700	0.016000	0.4317:0.1966:0.1615:0.2103	.	281;281;281;281;281;281;281;281;281;281;281;281;281;281;281;281;281;281;281;281;281	C4P094;C4P0A3;C4P098;C4P0A1;C4P0A4;A6NLH2;C4P0A5;C4P095;C4P0B6;C4P0C4;C4P091;C4P0D2;C4P0D3;C4P0B1;A7E2W8;Q5T409;C4P0D0;Q9NRI5-2;Q9NRI5;Q9NRI5-3;Q9NRI5-4	.;.;.;.;.;.;.;.;.;.;.;.;.;.;.;.;.;.;DISC1_HUMAN;.;.	T	281;281;281;281;281;281;281;281;281;281;281;281;132	ENSP00000403888:A281T;ENSP00000320784:A281T;ENSP00000355596:A281T;ENSP00000443996:A281T;ENSP00000440909:A281T;ENSP00000355593:A281T;ENSP00000440953:A281T;ENSP00000295051:A281T;ENSP00000441193:A281T	ENSP00000295051:A281T	A	+	1	0	DISC1	229896968	0	0.058580	0	0.037020	0	0.004340	-1.175000	0.031020	-1.334000	0.022440	-1.019000	0.024480	GCA		TCGA-HZ-7925-01A-11D-2154-08	DISC1-019	KNOWN	basic|appris_candidate|CCDS	protein_coding	protein_coding	OTTHUMT00000467451.1	1	0	0	31	344	0	48	0	1.446698e-01	0	8	0	48	2		0	0	0	0	0	2	1	1.000000	31	337	0	48	2		0	0	0	0	48	2	-2.966611	1	1	0	0		1	1	2	3	2.262092	1	0.240000	1.910000	0.320701	0.770000	0.540000	1.000000	1.000000	0.782606	0.770000	0	0.640000	0.920000
NCKAP5	344148	broad.mit.edu	37	2	133542683	133542683	+	Silent	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr2:133542683G>A	ENST00000409261.1	-	14	2074	c.1701C>T	c.(1699-1701)ggC>ggT	p.G567G	NCKAP5_ENST00000317721.6_Silent_p.G567G|NCKAP5_ENST00000405974.3_Intron|NCKAP5_ENST00000409213.1_Intron	NM_207363.2	NP_997246.2	O14513	NCKP5_HUMAN	NCK-associated protein 5			118					CATGGCCTTGGCCCTGTGGGC	0.542000																								0							SO:0001819	synonymous_variant			ENST00000409261.1	1	1	hg19	CCDS46418.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	NCKAP5-001	KNOWN	basic|appris_candidate_longest|CCDS	protein_coding	protein_coding	OTTHUMT00000331663.1	1	0	1	63	429	0	78		0	0	0	0	78	2		0	0	0	0	0	2	1	1.000000	61	420	0	78	2		0	0	0	0	78	2	-19.999990	1	1	0	0		1	1	2	3	2.035836	0	0.240000	1.910000	0.244533	0.990000	0.840000	1.000000	1.000000	0.981418	0.990000	1	0.950000	1.000000
AQPEP	0	broad.mit.edu	37	5	115327959	115327959	+	Silent	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr5:115327959C>T	ENST00000357872.4	+	5	1369	c.1245C>T	c.(1243-1245)caC>caT	p.H415H	AQPEP_ENST00000395528.2_5'UTR	NM_173800.4	NP_776161.3	Q6Q4G3	AMPQ_HUMAN									TTGTCTCCCACGAGATTGGAC	0.388000																								0							SO:0001819	synonymous_variant			ENST00000357872.4	1	1	hg19	CCDS4124.1																																																																																				TCGA-HZ-7925-01A-11D-2154-08	AQPEP-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000250852.1	1	0	0	63	383	0	76		0	0	0	0	76	2		0	0	0	0	0	2	1	1.000000	62	381	0	76	2		0	0	0	0	76	2	-20.000000	1	1	121404	8	43	1	1	2	3	2.036595	0	0.240000	1.910000	0.244533	0.990000	0.920000	1.000000	1.000000	0.995814	0.990000	1	0.990000	1.000000
PCDHA8	56140	broad.mit.edu	37	5	140222482	140222482	+	Missense_Mutation	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr5:140222482G>A	ENST00000531613.1	+	1	1576	c.1576G>A	c.(1576-1578)Gag>Aag	p.E526K	PCDHA3_ENST00000522353.2_Intron|PCDHA6_ENST00000527624.1_Intron|PCDHA4_ENST00000530339.1_Intron|PCDHA1_ENST00000504120.2_Intron|PCDHA4_ENST00000512229.2_Intron|PCDHA2_ENST00000526136.1_Intron|PCDHA7_ENST00000525929.1_Intron|PCDHA5_ENST00000529859.1_Intron|PCDHA1_ENST00000394633.3_Intron|PCDHA8_ENST00000378123.3_Missense_Mutation_p.E526K|PCDHA6_ENST00000529310.1_Intron|PCDHA5_ENST00000529619.1_Intron	NM_018911.2	NP_061734.1	Q9Y5H6	PCDA8_HUMAN	protocadherin alpha 8			78			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)		GCTGGACCACGAGGAGCTAGA	0.677000																								0							SO:0001583	missense			ENST00000531613.1	1	1	hg19	CCDS54919.1	.	.	.	.	.	.	.	.	.	.	G	21.600000	4.173878	0.784520	.	.	ENSG00000204962	ENST00000531613;ENST00000378123	T;T	0.72394	-0.65;-0.65	3.720000	3.720000	0.427060	Cadherin (5);Cadherin-like (1);	0	0.370530	U	2.270000e-03	D	0.90614	0.7057	H	0.99169	4.455	0.436220	D	0.996001	D;D	0.89917	1.0;1.0	D;D	0.97110	1.0;1.0	D	0.94761	0.7936	10	0.87932	D	0	.	15.515100	0.758180	0.0:0.0:1.0:0.0	.	526;526	Q9Y5H6;Q9Y5H6-2	PCDA8_HUMAN;.	K	526	ENSP00000434655:E526K;ENSP00000367363:E526K	ENSP00000367363:E526K	E	+	1	0	PCDHA8	140202666	1	0.714170	1	0.803570	2.460000e-01	0.257370	9.188000	0.949210	1.790000	0.525030	0.306000	0.203180	GAG		TCGA-HZ-7925-01A-11D-2154-08	PCDHA8-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000372830.2	1	0	1	116	955	0	193		0	0	0	0	193	2		0	0	0	0	0	2	1	1.000000	112	932	0	189	2		0	0	0	0	193	2	-20.000000	1	1	0	0		1	0	1	1	2.018057	0	0.240000	1.910000	0.238172	0.890000	0.740000	1.000000	1.000000	0.899032	0.890000	1	0.810000	0.980000
CPEB4	80315	broad.mit.edu	37	5	173337529	173337529	+	Missense_Mutation	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr5:173337529C>T	ENST00000265085.5	+	2	2583	c.1129C>T	c.(1129-1131)Cgc>Tgc	p.R377C	CPEB4_ENST00000522336.1_5'UTR|CPEB4_ENST00000517880.1_5'UTR|CPEB4_ENST00000519835.1_Missense_Mutation_p.R377C|CPEB4_ENST00000520867.1_Missense_Mutation_p.R377C|CPEB4_ENST00000334035.5_Missense_Mutation_p.R377C	NM_030627.2	NP_085130.2	Q17RY0	CPEB4_HUMAN	cytoplasmic polyadenylation element binding protein 4			20	Renal(175;0.000159)|Lung NSC(126;0.0128)|all_lung(126;0.0202)	Medulloblastoma(196;0.0399)|all_neural(177;0.0966)	Kidney(164;3.85e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000183)		TCTACAGGATCGCCCCAGGAC	0.368000																								0							SO:0001583	missense			ENST00000265085.5	1	1	hg19	CCDS4390.1	.	.	.	.	.	.	.	.	.	.	C	28.500000	4.923383	0.923190	.	.	ENSG00000113742	ENST00000265085;ENST00000520867;ENST00000334035;ENST00000519835	T;T;T;T	0.61859	0.24;0.09;0.2;0.07	6.070000	6.070000	0.986850	.	0	0.856820	D	0	T	0.76278	0.3965	M	0.65498	2.005	0.807220	D	1.000000	D;D;D;D	0.89917	1.0;1.0;1.0;1.0	D;D;D;D	0.71870	0.943;0.975;0.974;0.962	T	0.76217	-0.3040	10	0.87932	D	0	-13.1041	20.659300	0.996260	0.0:1.0:0.0:0.0	.	377;377;377;377	B7ZLQ8;Q17RY0-2;E5RJM0;Q17RY0	.;.;.;CPEB4_HUMAN	C	377	ENSP00000265085:R377C;ENSP00000429092:R377C;ENSP00000334533:R377C;ENSP00000429048:R377C	ENSP00000265085:R377C	R	+	1	0	CPEB4	173270135	1	0.714170	1	0.803570	9.930000e-01	0.825480	5.832000	0.693370	2.885000	0.990190	0.655000	0.942530	CGC		TCGA-HZ-7925-01A-11D-2154-08	CPEB4-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000252964.2	1	0	1	75	425	0	97	1	9.346005e-01	5	23	0	97	2		0	0	0	0	0	2	1	1.000000	73	414	0	95	2		0	0	0	0	97	2	-20.000000	1	1	0	0		1	0	1	1	2.018057	0	0.240000	1.910000	0.238172	0.990000	0.990000	1.000000	1.000000	0.998992	0.990000	1	0.990000	1.000000
PHACTR1	221692	broad.mit.edu	37	6	13230385	13230385	+	Missense_Mutation	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr6:13230385C>T	ENST00000379350.1	+	9	1480	c.1351C>T	c.(1351-1353)Cgg>Tgg	p.R451W	PHACTR1_ENST00000379345.2_Intron|PHACTR1_ENST00000332995.7_Missense_Mutation_p.R451W|PHACTR1_ENST00000457702.2_Missense_Mutation_p.R306W			Q9C0D0	PHAR1_HUMAN	phosphatase and actin regulator 1			26	Breast(50;0.0427)|Ovarian(93;0.12)	all_hematologic(90;0.122)|Lung SC(78;0.195)	Epithelial(50;0.146)|BRCA - Breast invasive adenocarcinoma(129;0.239)		GGATGAGGAGCGGCTGGAGCT	0.587000																								0							SO:0001583	missense			ENST00000379350.1	0	1	hg19		.	.	.	.	.	.	.	.	.	.	C	19.870000	3.906594	0.728680	0.0	1.19E-4	ENSG00000112137	ENST00000379350;ENST00000332995;ENST00000432934;ENST00000457702	T;T;T	0.39406	1.08;1.14;1.23	5.470000	-1.600000	0.084260	.	0	0.856820	D	0	T	0.44993	0.1320	L	0.47716	1.5	0.807220	D	1.000000	D;B;D	0.89917	1.0;0.274;1.0	D;B;D	0.83275	0.994;0.053;0.996	T	0.53774	-0.8391	10	0.59425	D	0.04	-14.544	17.679900	0.882400	0.3077:0.6923:0.0:0.0	.	520;451;451	E7ESR5;Q9C0D0;Q9C0D0-2	.;PHAR1_HUMAN;.	W	451;451;520;306	ENSP00000368655:R451W;ENSP00000329880:R451W;ENSP00000397669:R306W	ENSP00000329880:R451W	R	+	1	2	PHACTR1	13338364	9.830000e-01	0.350100	8.460000e-01	0.333780	9.870000e-01	0.754690	0.326000	0.196460	-0.430000	0.073180	0.557000	0.710580	CGG		TCGA-HZ-7925-01A-11D-2154-08	PHACTR1-001	KNOWN	basic|appris_candidate_longest	protein_coding	protein_coding	OTTHUMT00000039876.1	1	0	1	11	78	0	12	0	2.864392e-01	0	8	0	12	2		0	0	0	0	0	2	1	0.998303	10	75	0	11	2		0	0	0	0	12	2	-18.476740	1	1	120940	1	22	1	0	0	0	2.002742	0	0.240000	1.910000	0.230769	0.990000	0.550000	1.000000	1.000000	0.911907	0.990000	1	0.760000	1.000000
TNXB	7148	broad.mit.edu	37	6	32046935	32046935	+	Missense_Mutation	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr6:32046935C>T	ENST00000375244.3	-	11	4451	c.4250G>A	c.(4249-4251)cGt>cAt	p.R1417H	TNXB_ENST00000375247.2_Missense_Mutation_p.R1417H|RNA5SP206_ENST00000516703.1_RNA			P22105	TENX_HUMAN	tenascin XB			8					GCCCCCAACACGCACCGCCCG	0.662000																								0							SO:0001583	missense			ENST00000375244.3	1	1	hg19		.	.	.	.	.	.	.	.	.	.	C	13.460000	2.244413	0.396970	.	.	ENSG00000168477	ENST00000375244;ENST00000375247	T;T	0.57752	0.38;0.38	5.520000	4.640000	0.579460	.	0	0.413960	D	8.890000e-04	T	0.34978	0.0916	M	0.67397	2.05	0.297400	N	0.837148	P	0.50617	0.937	P	0.47645	0.553	T	0.22382	-1.0218	10	0.13108	T	0.6	.	9.608800	0.396500	0.1602:0.6853:0.1545:0.0	.	1417	P22105-3	.	H	1417	ENSP00000364393:R1417H;ENSP00000364396:R1417H	ENSP00000364393:R1417H	R	-	2	0	TNXB	32154913	4.590000e-01	0.257680	9.720000e-01	0.419010	4.800000e-02	0.145420	0.667000	0.251120	1.459000	0.478920	0.591000	0.815410	CGT		TCGA-HZ-7925-01A-11D-2154-08	TNXB-001	PUTATIVE	not_organism_supported|basic|appris_candidate_longest	protein_coding	protein_coding	OTTHUMT00000268927.2	1	0	1	81	736	0	128	0	1.877959e-01	0	8	0	128	2		0	0	0	0	0	2	1	1.000000	77	716	0	128	2		0	0	0	0	128	2	-19.999540	1	1	120852	1	31	1	0	0	0	2.000270	0	0.240000	1.910000	0.228896	0.810000	0.650000	0.980000	0.810000	0.818148	0.810000	0	0.720000	0.900000
HOXA3	3200	broad.mit.edu	37	7	27148069	27148069	+	Missense_Mutation	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr7:27148069C>T	ENST00000396352.4	-	3	996	c.797G>A	c.(796-798)cGc>cAc	p.R266H	HOXA3_ENST00000317201.2_Missense_Mutation_p.R266H|HOXA-AS2_ENST00000518088.1_RNA|HOXA3_ENST00000521401.1_5'Flank	NM_030661.4	NP_109377.1	O43365	HXA3_HUMAN	homeobox A3			29					CACGGGGCTGCGACTTGGAGA	0.602000													Esophageal Squamous(136;1368 1743 5685 7935 50360)											0							SO:0001583	missense			ENST00000396352.4	1	1	hg19	CCDS5404.1	.	.	.	.	.	.	.	.	.	.	C	15.880000	2.964113	0.535070	.	.	ENSG00000105997	ENST00000396352;ENST00000317201;ENST00000396350	D;D	0.87256	-2.23;-2.23	5.560000	5.560000	0.838230	.	5.316400e-02	0.644020	D	1.000000e-06	D	0.84097	0.5397	L	0.52206	1.635	0.536880	D	0.999979	P	0.38300	0.626	B	0.32022	0.139	D	0.84641	0.0695	10	0.49607	T	0.09	.	19.537600	0.952600	0.0:1.0:0.0:0.0	.	266	O43365	HXA3_HUMAN	H	266;266;108	ENSP00000379640:R266H;ENSP00000324884:R266H	ENSP00000324884:R266H	R	-	2	0	HOXA3	27114594	1	0.714170	1	0.803570	9.620000e-01	0.633680	3.592000	0.539930	2.620000	0.887290	0.655000	0.942530	CGC		TCGA-HZ-7925-01A-11D-2154-08	HOXA3-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000358708.2	1	0	0	81	650	0	125	1	9.755422e-01	9	40	0	125	2		0	0	0	0	0	2	1	1.000000	81	623	0	121	2		0	0	0	0	125	2	-20.000000	1	1	0	0		1	1	2	3	2.071254	0	0.240000	1.910000	0.250789	0.940000	0.750000	1.000000	1.000000	0.931777	0.940000	1	0.840000	1.000000
TRPM6	140803	broad.mit.edu	37	9	77423011	77423011	+	Missense_Mutation	SNP	C	C	T			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chr9:77423011C>T	ENST00000360774.1	-	14	1814	c.1577G>A	c.(1576-1578)cGc>cAc	p.R526H	TRPM6_ENST00000451710.3_Missense_Mutation_p.R526H|TRPM6_ENST00000376871.3_Intron|TRPM6_ENST00000376864.4_Missense_Mutation_p.R526H|TRPM6_ENST00000361255.3_Missense_Mutation_p.R521H|TRPM6_ENST00000376872.3_Missense_Mutation_p.R526H|TRPM6_ENST00000449912.2_Missense_Mutation_p.R521H	NM_017662.4	NP_060132.3	Q9BX84	TRPM6_HUMAN	transient receptor potential cation channel, subfamily M, member 6			126					GTAGTTGCTGCGATATGCTCT	0.388000																								0							SO:0001583	missense			ENST00000360774.1	1	1	hg19	CCDS6647.1	.	.	.	.	.	.	.	.	.	.	C	28.500000	4.924348	0.923190	.	.	ENSG00000119121	ENST00000360774;ENST00000451710;ENST00000376872;ENST00000449912;ENST00000361255;ENST00000376864;ENST00000312449;ENST00000448641	T;T;T;T;T;T	0.75704	-0.96;-0.96;0.42;-0.96;-0.96;-0.96	5.740000	5.740000	0.901520	.	1.552790e-01	0.644020	D	1.200000e-05	D	0.84365	0.5456	M	0.73372	2.23	0.584320	D	0.999992	D;D;D	0.89917	0.999;1.0;0.993	D;D;P	0.68765	0.917;0.96;0.805	D	0.85613	0.1259	10	0.87932	D	0	.	14.126300	0.652220	0.0:0.9285:0.0:0.0715	.	526;526;521	Q9BX84-5;Q9BX84;Q9BX84-3	.;TRPM6_HUMAN;.	H	526;526;526;521;521;526;189;189	ENSP00000354006:R526H;ENSP00000407341:R526H;ENSP00000366068:R526H;ENSP00000396672:R521H;ENSP00000354962:R521H;ENSP00000366060:R526H	ENSP00000309693:R189H	R	-	2	0	TRPM6	76612831	9.990000e-01	0.422020	9.950000e-01	0.509660	9.880000e-01	0.763860	4.079000	0.576130	2.715000	0.928440	0.655000	0.942530	CGC		TCGA-HZ-7925-01A-11D-2154-08	TRPM6-001	KNOWN	basic|CCDS	protein_coding	protein_coding	OTTHUMT00000052693.1	1	0	1	53	396	0	81		0	0	0	0	81	2		0	0	0	0	0	2	1	1.000000	53	391	0	80	2		0	0	0	0	81	2	-19.344830	1	1	0	0		1	1	2	3	2.022439	0	0.240000	1.910000	0.241820	0.980000	0.750000	1.000000	1.000000	0.946434	0.980000	1	0.860000	1.000000
L1CAM	3897	broad.mit.edu	37	X	153135631	153135631	+	Nonsense_Mutation	SNP	G	G	A			TCGA-HZ-7925-01A-11D-2154-08	TCGA-HZ-7925-10A-01D-2154-08			G	A	G	G		Valid	Somatic	Phase_I	WXS	targeted			Illumina GAIIx	923b6998-e4e5-4912-9081-b7bc081918e6	2c4fb285-71ad-4896-807b-6303c36b37fd	g.chrX:153135631G>A	ENST00000370060.1	-	9	1060	c.871C>T	c.(871-873)Cag>Tag	p.Q291*	L1CAM_ENST00000361981.3_Nonsense_Mutation_p.Q286*|L1CAM_ENST00000361699.4_Nonsense_Mutation_p.Q291*|L1CAM_ENST00000538883.1_Nonsense_Mutation_p.Q293*|L1CAM_ENST00000370055.1_Nonsense_Mutation_p.Q286*|L1CAM_ENST00000370057.3_Nonsense_Mutation_p.Q291*|L1CAM_ENST00000543994.1_Nonsense_Mutation_p.Q293*	NM_001278116.1	NP_001265045.1	P32004	L1CAM_HUMAN	L1 cell adhesion molecule			81	all_cancers(53;6.72e-15)|all_epithelial(53;3.19e-09)|all_lung(58;3.39e-06)|all_hematologic(71;4.25e-06)|Lung NSC(58;4.7e-06)|Acute lymphoblastic leukemia(192;6.56e-05)				TTGTGGTTCTGGTAGGTGACA	0.642000																								0							SO:0001587	stop_gained			ENST00000370060.1	0	1	hg19	CCDS14733.1	.	.	.	.	.	.	.	.	.	.	G	37.000000	6.085530	0.972710	.	.	ENSG00000198910	ENST00000370060;ENST00000543994;ENST00000370057;ENST00000538883;ENST00000361981;ENST00000370055;ENST00000361699	.	.	.	5.150000	4.220000	0.498570	.	2.222930e-01	0.312100	N	8.045000e-03	.	.	.	.	.	.	0.807220	A	1.000000	.	.	.	.	.	.	.	.	.	.	0.19147	T	0.46	.	12.262300	0.546580	0.0:0.2934:0.7066:0.0	.	.	.	.	X	291;293;291;293;286;286;291	.	ENSP00000355380:Q291X	Q	-	1	0	L1CAM	152788825	8.380000e-01	0.294610	1	0.803570	9.080000e-01	0.536900	0.530000	0.230360	2.283000	0.765280	0.529000	0.557590	CAG		TCGA-HZ-7925-01A-11D-2154-08	L1CAM-001	KNOWN	basic|appris_candidate|CCDS	protein_coding	protein_coding	OTTHUMT00000061094.2	1	0	1	200	604	0	132	0	3.658816e-01	0	5	0	132	2	1	1	211	644	0	520	2	1	1.000000	194	593	0	131	2		0	0	0	0	132	2	-6.683376	1	1	0	0		1	0	1	1			0.240000	1.910000	0.240000	0.960000	0.880000	1.000000	0.990000	0.964417	0.960000	1	0.920000	1.000000