Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
YTHDC1	91746	broad.mit.edu	37	4	69202911	69202911	+	Silent	SNP	T	T	C			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr4:69202911T>C	ENST00000344157.4	-	4	1052	c.717A>G	c.(715-717)gaA>gaG	p.E239E	YTHDC1_ENST00000355665.3_Silent_p.E239E|YTHDC1_ENST00000579690.1_Silent_p.E239E	NM_001031732.2	NP_001026902.1	Q96MU7	YTDC1_HUMAN	YTH domain containing 1	239	Glu-rich.									NS(1)|breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(10)|lung(7)|ovary(1)|prostate(1)|upper_aerodigestive_tract(2)	30						cctcctcctcttcctcctcct	0.473000													8	11					0	0	1	0	0
BCL2L14	79370	broad.mit.edu	37	12	12240321	12240321	+	Splice_Site	SNP	G	G	A			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr12:12240321G>A	ENST00000266434.4	+	3	802		c.e3+1		BCL2L14_ENST00000308721.5_Splice_Site|BCL2L14_ENST00000586576.1_Splice_Site|BCL2L14_ENST00000589718.1_Splice_Site|BCL2L14_ENST00000396369.1_Splice_Site|BCL2L14_ENST00000396367.1_Splice_Site	NM_030766.1	NP_110393.1	Q9BZR8	B2L14_HUMAN	BCL2-like 14 (apoptosis facilitator)						apoptosis|regulation of apoptosis	cytosol|endomembrane system|intracellular organelle|membrane	protein binding			large_intestine(1)|lung(2)|skin(3)	6		Prostate(47;0.0872)		BRCA - Breast invasive adenocarcinoma(232;0.154)		TCTAAGAAAGGTAAGCTTTCC	0.532000													5	60					0	0	1	0	0
OAZ3	51686	broad.mit.edu	37	1	151739705	151739705	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr1:151739705C>T	ENST00000321531.5	+	3	265	c.98C>T	c.(97-99)tCc>tTc	p.S33F	RP11-98D18.3_ENST00000512280.1_RNA|OAZ3_ENST00000479764.1_5'UTR|OAZ3_ENST00000400999.1_5'UTR|OAZ3_ENST00000453029.2_Missense_Mutation_p.S46F|OAZ3_ENST00000315067.8_Missense_Mutation_p.S33F|OAZ3_ENST00000577465.1_3'UTR			Q9UMX2	OAZ3_HUMAN	ornithine decarboxylase antizyme 3	30					cellular nitrogen compound metabolic process|regulation of cellular amino acid metabolic process|spermatogenesis	cytosol|nucleus	ornithine decarboxylase inhibitor activity			endometrium(2)|kidney(2)|large_intestine(1)|lung(4)	9	Hepatocellular(266;0.0877)|all_hematologic(923;0.127)|Melanoma(130;0.14)		LUSC - Lung squamous cell carcinoma(543;0.181)		L-Ornithine(DB00129)	GCTCCTGAGTCCCTAGTAGGC	0.512000													7	75					0	0	1	0	0
KLHL7	55975	broad.mit.edu	37	7	23207596	23207596	+	Missense_Mutation	SNP	G	G	T			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr7:23207596G>T	ENST00000322231.7	+	10	1743	c.1253G>T	c.(1252-1254)gGa>gTa	p.G418V	KLHL7_ENST00000409689.1_Missense_Mutation_p.G392V|KLHL7_ENST00000539124.1_Missense_Mutation_p.G364V|KLHL7_ENST00000542558.1_Missense_Mutation_p.G215V|KLHL7_ENST00000339077.4_Missense_Mutation_p.G440V|KLHL7_ENST00000545443.1_Missense_Mutation_p.G418V			Q8IXQ5	KLHL7_HUMAN	kelch-like family member 7	440						Golgi apparatus|nucleolus|plasma membrane				breast(1)|central_nervous_system(1)|kidney(2)|large_intestine(6)|lung(11)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	25						GGAAGTTTAGGAAACAATGTT	0.423000													25	51					3.01185e-09	3.6666e-09	1	1	0
INPP4A	3631	broad.mit.edu	37	2	99170841	99170841	+	Silent	SNP	G	G	A			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr2:99170841G>A	ENST00000074304.5	+	16	1863	c.1470G>A	c.(1468-1470)tcG>tcA	p.S490S	INPP4A_ENST00000409540.3_Silent_p.S490S|INPP4A_ENST00000409851.3_Silent_p.S485S|INPP4A_ENST00000409463.1_Intron|INPP4A_ENST00000545415.1_Silent_p.S490S|INPP4A_ENST00000409016.3_Silent_p.S490S|INPP4A_ENST00000523221.1_Silent_p.S490S	NM_001134224.1	NP_001127696.1	Q96PE3	INP4A_HUMAN	inositol polyphosphate-4-phosphatase, type I, 107kDa	490					signal transduction		phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity|phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity			breast(1)|endometrium(9)|kidney(2)|large_intestine(5)|lung(16)|ovary(2)|prostate(4)|upper_aerodigestive_tract(4)	43						CTCCCACTTCGACTGAGGAGG	0.602000													10	15					0	0	1	0	0
RP11-423O2.5	0	broad.mit.edu	37	1	142803543	142803543	+	RNA	SNP	C	C	T			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr1:142803543C>T	ENST00000423385.1	-	0	1422																											TGTTGGAATTCCTGATGAATC	0.269000													4	128					0	0	1	0	0
ANO3	63982	broad.mit.edu	37	11	26677925	26677925	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr11:26677925A>G	ENST00000256737.3	+	26	3512	c.2660A>G	c.(2659-2661)tAc>tGc	p.Y887C	ANO3_ENST00000537978.1_Missense_Mutation_p.Y871C|ANO3_ENST00000525139.1_Missense_Mutation_p.Y871C|ANO3_ENST00000531568.1_Missense_Mutation_p.Y741C	NM_031418.2	NP_113606.2	Q9BYT9	ANO3_HUMAN	anoctamin 3	887						chloride channel complex	chloride channel activity			breast(2)|central_nervous_system(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(12)|lung(33)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)	68						GATTTCAGGTACAGAGACTAC	0.388000													6	73					0	0	1	0	0
RSRC2	65117	broad.mit.edu	37	12	122990196	122990196	+	Nonsense_Mutation	SNP	G	G	A			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr12:122990196G>A	ENST00000331738.7	-	10	1328	c.1183C>T	c.(1183-1185)Cag>Tag	p.Q395*	RSRC2_ENST00000392442.2_5'UTR|RSRC2_ENST00000354654.2_Nonsense_Mutation_p.Q347*	NM_023012.5	NP_075388.2	Q7L4I2	RSRC2_HUMAN	arginine/serine-rich coiled-coil 2	395										breast(2)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(7)|ovary(1)|skin(2)|urinary_tract(2)	24	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;5.14e-05)|Epithelial(86;0.000183)|BRCA - Breast invasive adenocarcinoma(302;0.201)		TCTTCCTGCTGCTTCAGAGTC	0.373000													33	51					0	0	1	0	0
EMR3	84658	broad.mit.edu	37	19	14752291	14752291	+	Silent	SNP	C	C	T			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr19:14752291C>T	ENST00000253673.5	-	10	1288	c.1188G>A	c.(1186-1188)tcG>tcA	p.S396S	EMR3_ENST00000344373.4_Silent_p.S344S|EMR3_ENST00000599900.1_Silent_p.S181S|EMR3_ENST00000443157.2_Silent_p.S270S	NM_032571.3	NP_115960.2	Q9BY15	EMR3_HUMAN	egf-like module containing, mucin-like, hormone receptor-like 3	396					neuropeptide signaling pathway	extracellular space|integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity			NS(1)|autonomic_ganglia(1)|breast(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(12)|lung(14)|ovary(7)|prostate(2)|skin(4)|upper_aerodigestive_tract(1)	50						AGAGGCAGAGCGAGAGCTGCA	0.587000													16	25					0	0	1	0	0
CDT1	81620	broad.mit.edu	37	16	88874571	88874571	+	Missense_Mutation	SNP	G	G	C			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr16:88874571G>C	ENST00000301019.4	+	10	2145	c.1526G>C	c.(1525-1527)tGg>tCg	p.W509S		NM_030928.3	NP_112190.2	Q9H211	CDT1_HUMAN	chromatin licensing and DNA replication factor 1	509					DNA replication|DNA replication checkpoint|M/G1 transition of mitotic cell cycle|regulation of DNA-dependent DNA replication initiation|regulation of transcription involved in G1/S phase of mitotic cell cycle|S phase of mitotic cell cycle	cytosol|nucleoplasm	DNA binding|protein binding			central_nervous_system(1)|endometrium(2)|kidney(1)|lung(3)	7				BRCA - Breast invasive adenocarcinoma(80;0.0476)		CTGCCGGACTGGCTCAGCCTC	0.672000													4	22					0	0	1	0	0
CHRNB2	1141	broad.mit.edu	37	1	154548321	154548321	+	Silent	SNP	C	C	A			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr1:154548321C>A	ENST00000368476.3	+	6	1686	c.1422C>A	c.(1420-1422)acC>acA	p.T474T		NM_000748.2	NP_000739.1	P17787	ACHB2_HUMAN	cholinergic receptor, nicotinic, beta 2 (neuronal)	474					B cell activation|behavioral response to nicotine|calcium ion transport|central nervous system projection neuron axonogenesis|lateral geniculate nucleus development|locomotory behavior|membrane depolarization|memory|negative regulation of action potential|optic nerve morphogenesis|positive regulation of B cell proliferation|positive regulation of dopamine secretion|regulation of circadian sleep/wake cycle, REM sleep|regulation of dendrite morphogenesis|regulation of dopamine metabolic process|regulation of synaptogenesis|response to cocaine|response to ethanol|response to hypoxia|sensory perception of pain|sensory perception of sound|smooth muscle contraction|social behavior|synaptic transmission involved in micturition|synaptic transmission, cholinergic|vestibulocochlear nerve development|visual learning|visual perception	cell junction|external side of plasma membrane|nicotinic acetylcholine-gated receptor-channel complex|postsynaptic membrane	acetylcholine receptor activity|nicotinic acetylcholine-activated cation-selective channel activity			cervix(1)|endometrium(2)|kidney(1)|large_intestine(8)|lung(12)|skin(1)|urinary_tract(3)	28	all_lung(78;2.22e-29)|Lung NSC(65;3.66e-27)|Hepatocellular(266;0.0877)|all_hematologic(923;0.088)		LUSC - Lung squamous cell carcinoma(543;0.185)		Nicotine(DB00184)	TCTTTGGCACCATCGGCATGT	0.567000													4	95					3.59834e-05	3.73161e-05	1	1	0
POLR3B	55703	broad.mit.edu	37	12	106820987	106820987	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr12:106820987C>T	ENST00000228347.4	+	13	1336	c.1114C>T	c.(1114-1116)Ctt>Ttt	p.L372F	POLR3B_ENST00000539066.1_Missense_Mutation_p.L314F|POLR3B_ENST00000549195.1_3'UTR	NM_018082.5	NP_060552.4	Q9NW08	RPC2_HUMAN	polymerase (RNA) III (DNA directed) polypeptide B	372					innate immune response|positive regulation of innate immune response|positive regulation of interferon-beta production|response to virus|termination of RNA polymerase III transcription|transcription elongation from RNA polymerase III promoter	nucleoplasm	DNA binding|DNA-directed RNA polymerase activity|metal ion binding|ribonucleoside binding	p.L372F(2)		breast(2)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(14)|lung(22)|ovary(1)|prostate(3)|skin(3)|urinary_tract(2)	57						TTTATCTCTTCTTTTTGAAGA	0.274000													5	8					0	0	1	0	0
GOLGA8DP	100132979	broad.mit.edu	37	15	22709637	22709637	+	RNA	SNP	T	T	G	rs140467724	by1000genomes	TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr15:22709637T>G	ENST00000314246.8	-	0	1147																											CCCATCTGGTTTTTGAGTTTG	0.547000													4	221					0	0	1	0	0
POM121L9P	29774	broad.mit.edu	37	22	24659591	24659591	+	RNA	SNP	A	A	G			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr22:24659591A>G	ENST00000414583.2	+	0	3116					NR_003714.1																						ACTCACTGACATCGAAGGCTG	0.632000													3	16					0	0	1	0	0
ZNF844	284391	broad.mit.edu	37	19	12187394	12187394	+	Missense_Mutation	SNP	T	T	C			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr19:12187394T>C	ENST00000439326.3	+	4	1634	c.1459T>C	c.(1459-1461)Ttt>Ctt	p.F487L	ZNF844_ENST00000441304.2_3'UTR	NM_001136501.1	NP_001129973.1	Q08AG5	ZN844_HUMAN	zinc finger protein 844	487					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding	p.F487L(1)		NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|kidney(2)|lung(1)|prostate(1)	10						GCCTTCATTTTTTCCACTTCC	0.448000													3	56					0	0	1	0	0
CMYA5	202333	broad.mit.edu	37	5	79032506	79032506	+	Missense_Mutation	SNP	C	C	G			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr5:79032506C>G	ENST00000446378.2	+	2	7949	c.7918C>G	c.(7918-7920)Ctt>Gtt	p.L2640V		NM_153610.3	NP_705838.3	Q8N3K9	CMYA5_HUMAN	cardiomyopathy associated 5	2640						perinuclear region of cytoplasm				NS(2)|breast(4)|central_nervous_system(1)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(4)|kidney(4)|large_intestine(37)|lung(34)|ovary(6)|pancreas(2)|prostate(5)|skin(5)|stomach(11)|upper_aerodigestive_tract(3)|urinary_tract(1)	128		Lung NSC(167;0.00296)|all_lung(232;0.00327)|Ovarian(174;0.0262)		OV - Ovarian serous cystadenocarcinoma(54;9.85e-46)|Epithelial(54;3.38e-40)|all cancers(79;3.43e-35)		GCCGGTGGCTCTTTCTTGTCG	0.413000													15	26					0	0	1	0	0
WNT9B	7484	broad.mit.edu	37	17	44952701	44952701	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr17:44952701C>A	ENST00000393461.2	+	3	622	c.569C>A	c.(568-570)gCa>gAa	p.A190E	WNT9B_ENST00000290015.2_Missense_Mutation_p.A190E			O14905	WNT9B_HUMAN	wingless-type MMTV integration site family, member 9B	190					anterior/posterior pattern formation|axis specification|branching involved in ureteric bud morphogenesis|canonical Wnt receptor signaling pathway|cell-cell signaling|cellular response to retinoic acid|collecting duct development|cornea development in camera-type eye|endoderm development|establishment of planar polarity involved in nephron morphogenesis|kidney rudiment formation|male genitalia development|mesonephric duct formation|metanephric tubule development|neuron differentiation|palate development|regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|uterus morphogenesis|Wnt receptor signaling pathway, calcium modulating pathway|Wnt receptor signaling pathway, planar cell polarity pathway	extracellular space|plasma membrane|proteinaceous extracellular matrix	extracellular matrix structural constituent|G-protein-coupled receptor binding			large_intestine(2)|lung(8)	10			BRCA - Breast invasive adenocarcinoma(9;0.0257)			CGGGCACGGGCAGACGCCCAC	0.607000													9	11					2.17888e-05	2.44034e-05	1	1	0
SEC22B	9554	broad.mit.edu	37	1	145109547	145109547	+	RNA	SNP	G	G	T			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr1:145109547G>T	ENST00000453618.1	+	0	536							O75396	SC22B_HUMAN	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)						ER to Golgi vesicle-mediated transport|protein transport	endoplasmic reticulum membrane|ER-Golgi intermediate compartment membrane|Golgi membrane|integral to membrane|melanosome	protein binding										CAGGGGGTGTGTGATTTGGTT	0.403000													9	206					0.000274275	0.000274275	1	1	0
BCRP7	100133163	broad.mit.edu	37	22	18844766	18844766	+	RNA	SNP	G	G	A			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr22:18844766G>A	ENST00000412938.1	+	0	3016																											CAGCCTCTGAGGGCAGCAGTG	0.557000													7	10					0	0	1	0	0
NUTM2B-AS1	101060691	broad.mit.edu	37	10	81444141	81444143	+	RNA	DEL	AGG	AGG	-			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr10:81444141_81444143delAGG	ENST00000600376.1	-	0	54				RP11-119F19.2_ENST00000596088.1_RNA																							CCCCACATGCAGGAGGAGGAGGC	0.665													2	4	---	---	---	---					
NF1	4763	broad.mit.edu	37	17	29588743	29588743	+	Frame_Shift_Del	DEL	T	T	-			TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr17:29588743delT	ENST00000358273.4	+	35	4975	c.4592delT	c.(4591-4593)gtfs	p.V1531fs	NF1_ENST00000356175.3_Frame_Shift_Del_p.V1510fs	NM_001042492.2	NP_001035957.1	P21359	NF1_HUMAN	neurofibromin 1	1531					actin cytoskeleton organization|adrenal gland development|artery morphogenesis|camera-type eye morphogenesis|cerebral cortex development|collagen fibril organization|forebrain astrocyte development|forebrain morphogenesis|heart development|liver development|MAPKKK cascade|metanephros development|myelination in peripheral nervous system|negative regulation of cell migration|negative regulation of endothelial cell proliferation|negative regulation of MAP kinase activity|negative regulation of MAPKKK cascade|negative regulation of neuroblast proliferation|negative regulation of oligodendrocyte differentiation|negative regulation of transcription factor import into nucleus|osteoblast differentiation|phosphatidylinositol 3-kinase cascade|pigmentation|positive regulation of adenylate cyclase activity|positive regulation of neuron apoptosis|Ras protein signal transduction|regulation of blood vessel endothelial cell migration|regulation of bone resorption|response to hypoxia|smooth muscle tissue development|spinal cord development|sympathetic nervous system development|visual learning|wound healing	axon|cytoplasm|dendrite|intrinsic to internal side of plasma membrane|nucleus	protein binding|Ras GTPase activator activity	p.0?(8)|p.?(4)	NF1/ACCN1(2)	autonomic_ganglia(12)|breast(11)|central_nervous_system(72)|cervix(6)|endometrium(12)|haematopoietic_and_lymphoid_tissue(59)|kidney(9)|large_intestine(39)|liver(1)|lung(80)|ovary(20)|pancreas(2)|prostate(2)|skin(8)|soft_tissue(249)|stomach(2)|thyroid(1)|upper_aerodigestive_tract(5)|urinary_tract(9)	599		all_cancers(10;1.29e-12)|all_epithelial(10;0.00347)|all_hematologic(16;0.00556)|Acute lymphoblastic leukemia(14;0.00593)|Breast(31;0.014)|Myeloproliferative disorder(56;0.0255)|all_lung(9;0.0321)|Lung NSC(157;0.0659)		UCEC - Uterine corpus endometrioid carcinoma (4;4.38e-05)|all cancers(4;1.64e-26)|Epithelial(4;9.15e-23)|OV - Ovarian serous cystadenocarcinoma(4;3.58e-21)|GBM - Glioblastoma multiforme(4;0.00146)		CATAAAGCTGTTGGAAGACGA	0.408			"""D, Mis, N, F, S, O"""		"""neurofibroma, glioma"""	"""neurofibroma, glioma"""			Neurofibromatosis, type 1	TCGA GBM(6;<1E-08)|TSP Lung(7;0.0071)|TCGA Ovarian(3;0.0088)			46	22	---	---	---	---					
ZNF880	400713	broad.mit.edu	37	19	52877717	52877717	+	Frame_Shift_Del	DEL	T	T	-	rs77187934		TCGA-RW-A689-01A-11D-A35D-08	TCGA-RW-A689-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	93918bc2-656a-4ea8-916a-361d7365c2ad	cab6cf4c-bb49-4543-8e1e-ea6b42497e1c	g.chr19:52877717delT	ENST00000597976.1	+	3	325	c.305delT	c.(304-306)atfs	p.I102fs	ZNF880_ENST00000424032.2_Intron|ZNF880_ENST00000600321.1_Intron|ZNF880_ENST00000422689.2_Intron|ZNF880_ENST00000344085.5_Intron			Q6PDB4	ZN880_HUMAN	zinc finger protein 880	0					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding			breast(1)|endometrium(3)|kidney(1)|large_intestine(2)|lung(2)|skin(1)	10						GGCCCCATAAttttttttttt	0.473													3	5	---	---	---	---