Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PSG7	5676	broad.mit.edu	37	19	43439887	43439887	+	RNA	SNP	T	T	A			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr19:43439887T>A	ENST00000406070.2	-	0	195				PSG7_ENST00000446844.3_RNA	NM_002783.2	NP_002774.2	Q13046	PSG7_HUMAN	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)						female pregnancy	extracellular region							Prostate(69;0.00682)				TGACTTGGGCTGTGGTGGGCG	0.493000													5	182					0	0	1	0	0
TPTE2P2	644623	broad.mit.edu	37	13	52855033	52855033	+	RNA	SNP	A	A	G			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr13:52855033A>G	ENST00000451298.1	-	0	396				RP11-64P12.8_ENST00000606031.1_RNA																							GTCTTTTTAGATGAGCCAGAT	0.343000													6	14					0	0	1	0	0
HIST1H2BC	8347	broad.mit.edu	37	6	26123939	26123939	+	Missense_Mutation	SNP	G	G	T			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr6:26123939G>T	ENST00000314332.5	-	1	199	c.194C>A	c.(193-195)tCt>tAt	p.S65Y	HIST1H2BC_ENST00000396984.1_Missense_Mutation_p.S65Y			P62807	H2B1C_HUMAN	histone cluster 1, H2bc	65					defense response to bacterium|nucleosome assembly	nucleosome|nucleus	DNA binding|protein binding	p.S65Y(1)		NS(1)|breast(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(1)|lung(9)|ovary(1)	16						GTTAACGAAAGAATTCATGAT	0.562000													50	115					3.21987e-24	3.62236e-24	1	1	0
KDM5A	5927	broad.mit.edu	37	12	464375	464375	+	Silent	SNP	G	G	A			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr12:464375G>A	ENST00000399788.2	-	7	1181	c.819C>T	c.(817-819)gaC>gaT	p.D273D	KDM5A_ENST00000382815.4_Silent_p.D273D	NM_001042603.1	NP_001036068.1	P29375	KDM5A_HUMAN	lysine (K)-specific demethylase 5A	273					chromatin modification|multicellular organismal development|positive regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	cytoplasm|nucleolus	DNA binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(2)|breast(4)|central_nervous_system(2)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(14)|lung(29)|ovary(1)|prostate(5)|skin(6)|stomach(1)|urinary_tract(2)	77						TGTTAAATGCGTCTGACCTGT	0.373000			T	NUP98	AML								6	67					0	0	1	0	0
AFF4	27125	broad.mit.edu	37	5	132272835	132272835	+	Missense_Mutation	SNP	C	C	T			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr5:132272835C>T	ENST00000265343.5	-	2	426	c.47G>A	c.(46-48)aGg>aAg	p.R16K	AFF4_ENST00000378595.3_Missense_Mutation_p.R16K|AFF4_ENST00000491831.1_5'UTR	NM_014423.3	NP_055238.1	Q9UHB7	AFF4_HUMAN	AF4/FMR2 family, member 4	16					transcription from RNA polymerase II promoter	mitochondrion|nucleolus	protein binding|sequence-specific DNA binding transcription factor activity		SEPT8/AFF4(2)	breast(2)|central_nervous_system(2)|endometrium(6)|kidney(6)|large_intestine(7)|lung(11)|ovary(3)|pancreas(1)|prostate(3)|skin(2)	43		all_cancers(142;0.145)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)			CTGATTCCGCCTTTCCCGTTC	0.433000													5	35					0	0	1	0	0
MED30	90390	broad.mit.edu	37	8	118533175	118533175	+	Missense_Mutation	SNP	G	G	C			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr8:118533175G>C	ENST00000297347.3	+	1	224	c.60G>C	c.(58-60)caG>caC	p.Q20H	MED30_ENST00000522839.1_Missense_Mutation_p.Q20H	NM_080651.2	NP_542382.1	Q96HR3	MED30_HUMAN	mediator complex subunit 30	20					androgen receptor signaling pathway|positive regulation of transcription, DNA-dependent|transcription initiation from RNA polymerase II promoter	mediator complex	ligand-dependent nuclear receptor transcription coactivator activity|receptor activity|RNA polymerase II transcription cofactor activity|thyroid hormone receptor binding|vitamin D receptor binding			kidney(1)|lung(3)|prostate(3)	7	all_cancers(13;3.41e-25)|Lung NSC(37;3.02e-05)|Ovarian(258;0.00163)		STAD - Stomach adenocarcinoma(47;0.0266)			CCGGGCCCCAGGCTCAGCAGG	0.706000													5	24					0	0	1	0	0
MAPK6	5597	broad.mit.edu	37	15	52339183	52339183	+	Missense_Mutation	SNP	C	C	T			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr15:52339183C>T	ENST00000261845.5	+	2	1333	c.526C>T	c.(526-528)Cgg>Tgg	p.R176W		NM_002748.3	NP_002739.1	Q16659	MK06_HUMAN	mitogen-activated protein kinase 6	176	Protein kinase.				cell cycle		ATP binding|MAP kinase activity			breast(3)|endometrium(1)|kidney(3)|large_intestine(3)|lung(7)|ovary(1)|skin(2)	20				all cancers(107;0.0028)		TGGTCTTGCACGGATCATGGA	0.383000													24	64					0	0	1	0	0
GLUD1P7	414212	broad.mit.edu	37	10	48968566	48968566	+	RNA	SNP	A	A	G			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr10:48968566A>G	ENST00000594520.1	+	0	723																											ACAGGATAACAAACTGGAAAA	0.318000													4	26					0	0	1	0	0
ATP1B4	23439	broad.mit.edu	37	X	119505020	119505020	+	Missense_Mutation	SNP	G	G	C			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chrX:119505020G>C	ENST00000218008.3	+	4	574	c.517G>C	c.(517-519)Gac>Cac	p.D173H	ATP1B4_ENST00000539306.1_Missense_Mutation_p.D130H|ATP1B4_ENST00000361319.3_Missense_Mutation_p.D169H	NM_001142447.2	NP_001135919.1	Q9UN42	AT1B4_HUMAN	ATPase, Na+/K+ transporting, beta 4 polypeptide	173					ATP biosynthetic process|regulation of transcription, DNA-dependent|transcription, DNA-dependent	integral to plasma membrane|nuclear inner membrane	sodium:potassium-exchanging ATPase activity			breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(3)|lung(14)|ovary(2)|pancreas(1)|skin(4)|upper_aerodigestive_tract(1)	33						TTCTGAACCCGACACTTGGCA	0.428000													11	52					0	0	1	0	0
HTT	3064	broad.mit.edu	37	4	3237362	3237362	+	Missense_Mutation	SNP	G	G	T			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr4:3237362G>T	ENST00000355072.5	+	63	8787	c.8642G>T	c.(8641-8643)gGc>gTc	p.G2881V		NM_002111.6	NP_002102.4	P42858	HD_HUMAN	huntingtin	2881					establishment of mitotic spindle orientation|Golgi organization|retrograde vesicle-mediated transport, Golgi to ER|vesicle transport along microtubule	autophagic vacuole|axon|cytoplasmic vesicle membrane|cytosol|dendrite|endoplasmic reticulum|Golgi apparatus|late endosome|membrane fraction|nucleus|protein complex	beta-tubulin binding|dynactin binding|dynein intermediate chain binding|p53 binding|transcription factor binding			breast(1)|cervix(2)|endometrium(14)|kidney(5)|large_intestine(23)|lung(28)|ovary(4)|prostate(2)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	87		all_epithelial(65;0.18)		UCEC - Uterine corpus endometrioid carcinoma (64;0.187)		GCCCTCAGAGGCCTGGAGCGC	0.597000													10	23					4.68919e-08	4.96502e-08	1	1	0
FAM167A	83648	broad.mit.edu	37	8	11282013	11282013	+	Nonsense_Mutation	SNP	C	C	A			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr8:11282013C>A	ENST00000284486.4	-	3	1052	c.514G>T	c.(514-516)Gag>Tag	p.E172*	FAM167A_ENST00000531564.1_5'UTR|FAM167A_ENST00000528897.1_Nonsense_Mutation_p.E172*|C8orf12_ENST00000284481.3_Intron|FAM167A_ENST00000534308.1_Nonsense_Mutation_p.E172*|C8orf12_ENST00000529305.1_Intron	NM_053279.2	NP_444509.2	Q96KS9	F167A_HUMAN	family with sequence similarity 167, member A	172										breast(1)|endometrium(1)|large_intestine(4)|lung(2)|prostate(1)	9						TCCCGCTCCTCCAGCTCGTAG	0.577000													4	47					1	1	1	1	0
BARHL1	56751	broad.mit.edu	37	9	135458232	135458232	+	Silent	SNP	C	C	T			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr9:135458232C>T	ENST00000263610.2	+	1	661	c.48C>T	c.(46-48)cgC>cgT	p.R16R	BARHL1_ENST00000542090.1_Silent_p.R16R	NM_020064.3	NP_064448.1	Q9BZE3	BARH1_HUMAN	BarH-like homeobox 1	16						nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			cervix(1)|large_intestine(2)|lung(2)|skin(3)	8				OV - Ovarian serous cystadenocarcinoma(145;1.79e-06)|Epithelial(140;3.12e-05)		TCTCCCACCGCGCGGGCAGCC	0.657000													24	62					0	0	1	0	0
GOLGA6L17P	642402	broad.mit.edu	37	15	85053142	85053142	+	RNA	SNP	C	C	T			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr15:85053142C>T	ENST00000414190.2	-	0	310					NR_003246.2																						TTTTTCAATTCCTTGACCCGC	0.413000													3	13					0	0	1	0	0
DBF4	10926	broad.mit.edu	37	7	87514300	87514302	+	In_Frame_Del	DEL	GAA	GAA	-			TCGA-W2-A7HB-01A-11D-A35I-08	TCGA-W2-A7HB-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	96444e23-d731-4c24-b5d0-8a697a0bf183	e99ae8f1-1162-48f6-ad7d-289880357334	g.chr7:87514300_87514302delGAA	ENST00000265728.1	+	3	730_732	c.226_228delGAA	c.(226-228)del	p.E77del		NM_006716.3	NP_006707.1	Q9UBU7	DBF4A_HUMAN	DBF4 homolog (S. cerevisiae)	77	BRCT 1.				cell cycle checkpoint|DNA replication|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle	nucleoplasm	enzyme activator activity|nucleic acid binding|protein binding|zinc ion binding			endometrium(4)|kidney(1)|large_intestine(6)|lung(13)|ovary(1)|skin(3)	28	Esophageal squamous(14;0.00202)	Breast(660;0.0334)				CTAGCGAGTTGAAGAATTTCTCA	0.350													10	41	---	---	---	---