Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FCRL6	343413	broad.mit.edu	37	1	159778167	159778167	+	Silent	SNP	T	T	C			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr1:159778167T>C	ENST00000321935.6	+	4	359	c.273T>C	c.(271-273)tcT>tcC	p.S91S	FCRL6_ENST00000392235.3_Silent_p.S84S|FCRL6_ENST00000368106.3_Silent_p.S84S|FCRL6_ENST00000339348.5_Silent_p.S84S			Q6DN72	FCRL6_HUMAN	Fc receptor-like 6	84	Ig-like C2-type 1.					integral to membrane				NS(1)|breast(1)|cervix(1)|endometrium(1)|large_intestine(2)|lung(8)|ovary(2)|prostate(1)|skin(4)|stomach(2)|upper_aerodigestive_tract(1)	24	all_hematologic(112;0.0597)					ACAGCTGCTCTGGGCAGGTGA	0.498000													9	34					0	0	1	0	0
FCRL3	115352	broad.mit.edu	37	1	157665168	157665168	+	Missense_Mutation	SNP	G	G	T			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr1:157665168G>T	ENST00000368184.3	-	8	1653	c.1362C>A	c.(1360-1362)gaC>gaA	p.D454E	FCRL3_ENST00000368186.5_Missense_Mutation_p.D454E|RP11-367J7.3_ENST00000453692.1_RNA|FCRL3_ENST00000473231.1_5'UTR	NM_052939.3	NP_443171.2	Q96P31	FCRL3_HUMAN	Fc receptor-like 3	454	Ig-like C2-type 5.					integral to membrane|plasma membrane	receptor activity			autonomic_ganglia(1)|breast(3)|endometrium(7)|kidney(1)|large_intestine(13)|lung(31)|ovary(3)|prostate(3)|skin(5)|upper_aerodigestive_tract(2)	69	all_hematologic(112;0.0378)					CCAGGCCATTGTCTGCATCAC	0.532000													5	84					0.184627	0.184627	1	1	0
FANCM	57697	broad.mit.edu	37	14	45650703	45650703	+	Silent	SNP	A	A	G			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr14:45650703A>G	ENST00000267430.5	+	15	4378	c.4293A>G	c.(4291-4293)aaA>aaG	p.K1431K	FANCM_ENST00000555013.1_3'UTR|FANCM_ENST00000542564.2_Silent_p.K1405K	NM_020937.2	NP_065988.1	Q8IYD8	FANCM_HUMAN	Fanconi anemia, complementation group M	1431					DNA repair	Fanconi anaemia nuclear complex	ATP binding|ATP-dependent helicase activity|chromatin binding|DNA binding|nuclease activity|protein binding			breast(4)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(18)|liver(2)|lung(31)|ovary(4)|prostate(2)|skin(1)|upper_aerodigestive_tract(6)|urinary_tract(1)	85						AAAGAGCAAAAGGAAATGTTT	0.308000								Involved in tolerance or repair of DNA crosslinks	Fanconi Anemia				13	40					0	0	1	0	0
LOC220729	220729	broad.mit.edu	37	3	197348634	197348634	+	RNA	SNP	G	G	C			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr3:197348634G>C	ENST00000418868.1	-	0	625					NR_003266.2																						CAGCAGCACCGATGGGCCTGC	0.542000													4	45					0	0	1	0	0
FEZ1	9638	broad.mit.edu	37	11	125359671	125359671	+	Translation_Start_Site	SNP	C	C	T			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr11:125359671C>T	ENST00000278919.3	-	2	237	c.3G>A	c.(1-3)atG>atA	p.M1I	FEZ1_ENST00000366139.3_Start_Codon_SNP_p.M1I|FEZ1_ENST00000524435.1_Start_Codon_SNP_p.M1I	NM_005103.4	NP_005094.1	Q99689	FEZ1_HUMAN	fasciculation and elongation protein zeta 1 (zygin I)	1					axon guidance|cell adhesion|transport	microtubule|plasma membrane				breast(1)|central_nervous_system(3)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|lung(9)|ovary(1)|upper_aerodigestive_tract(1)	24	all_hematologic(175;0.228)	Breast(109;0.0021)|Lung NSC(97;0.0126)|all_lung(97;0.0132)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;1.49e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0934)		GTGGGGCCTCCATTCTTGCTC	0.478000													10	21					0	0	1	0	0
ENOX2	10495	broad.mit.edu	37	X	129759353	129759353	+	Missense_Mutation	SNP	C	C	G			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chrX:129759353C>G	ENST00000338144.3	-	16	2185	c.1768G>C	c.(1768-1770)Gga>Cga	p.G590R	ENOX2_ENST00000394363.1_Missense_Mutation_p.G561R|ENOX2_ENST00000370935.1_Missense_Mutation_p.G561R|ENOX2_ENST00000370927.1_Missense_Mutation_p.G590R	NM_182314.1	NP_872114.1	Q16206	ENOX2_HUMAN	ecto-NOX disulfide-thiol exchanger 2	590					cell growth|electron transport chain|regulation of growth|transport|ultradian rhythm	cytosol|external side of plasma membrane|extracellular space	nucleic acid binding|nucleotide binding|protein disulfide oxidoreductase activity			breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(17)|ovary(1)|prostate(3)	33						GCTCCAACTCCAGTCATTTCC	0.483000													4	65					0	0	1	0	0
MLLT3	4300	broad.mit.edu	37	9	20414343	20414343	+	Silent	SNP	A	A	G			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr9:20414343A>G	ENST00000380338.4	-	5	787	c.501T>C	c.(499-501)agT>agC	p.S167S	MLLT3_ENST00000429426.2_Silent_p.S164S|MLLT3_ENST00000355930.6_5'UTR|MLLT3_ENST00000475957.1_5'UTR	NM_004529.2	NP_004520.2	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	167	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding	p.S167S(19)		central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(6)|lung(24)|ovary(1)|prostate(4)|skin(1)|urinary_tract(7)	66				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)		tgctgctgctactgctgctgc	0.532000			T	MLL	ALL								4	56					0	0	1	0	0
HERC2P2	400322	broad.mit.edu	37	15	23299928	23299928	+	RNA	SNP	C	C	T	rs142794095	by1000genomes	TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr15:23299928C>T	ENST00000560464.1	-	0	4359																											GCAAGCCGGACGCATTCCCGG	0.572000													3	7					0	0	1	0	0
OR6C6	283365	broad.mit.edu	37	12	55688981	55688981	+	Silent	SNP	G	G	C			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr12:55688981G>C	ENST00000358433.2	-	1	35	c.36C>G	c.(34-36)ctC>ctG	p.L12L		NM_001005493.1	NP_001005493.1	A6NF89	OR6C6_HUMAN	olfactory receptor, family 6, subfamily C, member 6	12					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|central_nervous_system(1)|kidney(2)|large_intestine(5)|lung(7)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	20						TCAATCCTAGGAGAATGAACT	0.333000													6	29					0	0	1	0	0
TIPARP	25976	broad.mit.edu	37	3	156421292	156421292	+	Missense_Mutation	SNP	G	G	A			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr3:156421292G>A	ENST00000461166.1	+	5	1915	c.1327G>A	c.(1327-1329)Gtc>Atc	p.V443I	TIPARP_ENST00000486483.1_Missense_Mutation_p.V443I|TIPARP_ENST00000295924.7_Missense_Mutation_p.V443I|TIPARP_ENST00000542783.1_Missense_Mutation_p.V443I	NM_001184717.1	NP_001171646.1	Q7Z3E1	PARPT_HUMAN	TCDD-inducible poly(ADP-ribose) polymerase	443							NAD+ ADP-ribosyltransferase activity|nucleic acid binding|protein binding|zinc ion binding			NS(1)|breast(2)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(7)|lung(4)|ovary(2)|skin(2)|upper_aerodigestive_tract(2)	23			LUSC - Lung squamous cell carcinoma(72;0.0461)|Lung(72;0.0465)			CCCAGATGGGGTCACTTCAGC	0.448000													3	39					0	0	1	0	0
SESN1	27244	broad.mit.edu	37	6	109315808	109315808	+	Missense_Mutation	SNP	C	C	G			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr6:109315808C>G	ENST00000436639.2	-	6	1722	c.977G>C	c.(976-978)aGt>aCt	p.S326T	SESN1_ENST00000356644.7_Missense_Mutation_p.S267T|SESN1_ENST00000302071.2_Missense_Mutation_p.S201T	NM_014454.2	NP_055269.1	Q9Y6P5	SESN1_HUMAN	sestrin 1	267					cell cycle arrest|negative regulation of cell proliferation|response to DNA damage stimulus	nucleus				cervix(1)|large_intestine(3)|lung(3)|ovary(1)|skin(1)|urinary_tract(1)	10		all_cancers(87;6.45e-05)|Acute lymphoblastic leukemia(125;3.55e-10)|all_hematologic(75;1.68e-07)|all_epithelial(87;0.0106)|Colorectal(196;0.0637)		Epithelial(106;0.0014)|BRCA - Breast invasive adenocarcinoma(108;0.00146)|all cancers(137;0.0031)|OV - Ovarian serous cystadenocarcinoma(136;0.0117)		GAAAGAATCACTTACCTGAAG	0.343000													4	22					0	0	1	0	0
TYW1	55253	broad.mit.edu	37	7	66479502	66479502	+	Missense_Mutation	SNP	C	C	T			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr7:66479502C>T	ENST00000359626.5	+	5	688	c.524C>T	c.(523-525)gCg>gTg	p.A175V		NM_018264.2	NP_060734.2	Q9NV66	TYW1_HUMAN	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)	175	Flavodoxin-like.				tRNA processing		4 iron, 4 sulfur cluster binding|FMN binding|iron ion binding|oxidoreductase activity			breast(1)|endometrium(8)|kidney(10)|large_intestine(4)|lung(13)|ovary(1)|prostate(2)|skin(3)|stomach(2)|urinary_tract(2)	46		Lung NSC(55;0.0846)|all_lung(88;0.183)				ATGAGATATGCGGTATTTGGC	0.423000													4	144					0	0	1	0	0
ANKFN1	162282	broad.mit.edu	37	17	54559863	54559863	+	Silent	SNP	C	C	T			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr17:54559863C>T	ENST00000566473.2	+	17	2247	c.2247C>T	c.(2245-2247)ctC>ctT	p.L749L	ANKFN1_ENST00000318698.2_Silent_p.L749L			Q8N957	ANKF1_HUMAN	ankyrin-repeat and fibronectin type III domain containing 1	749										NS(1)|breast(1)|cervix(2)|endometrium(4)|kidney(4)|large_intestine(11)|lung(27)|ovary(1)|prostate(1)|skin(1)	53						TTCTTAACCTCCCTCTTCAGA	0.438000													21	60					0	0	1	0	0
KANSL1	284058	broad.mit.edu	37	17	44248901	44248901	+	Silent	SNP	C	C	T			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr17:44248901C>T	ENST00000262419.6	-	2	1079	c.609G>A	c.(607-609)ggG>ggA	p.G203G	KANSL1_ENST00000393476.3_5'UTR|KANSL1_ENST00000575318.1_Silent_p.G203G|KANSL1_ENST00000574590.1_Silent_p.G203G|KANSL1_ENST00000572904.1_Silent_p.G203G|KANSL1_ENST00000432791.1_Silent_p.G203G	NM_001193466.1	NP_001180395.1	Q7Z3B3	K1267_HUMAN	KAT8 regulatory NSL complex subunit 1	203						MLL1 complex	protein binding										TGGTCATACCCCCCTTCAAGT	0.453000													22	80					0	0	1	0	0
TTLL8	164714	broad.mit.edu	37	22	50483807	50483807	+	Missense_Mutation	SNP	G	G	A			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr22:50483807G>A	ENST00000266182.6	-	6	519	c.520C>T	c.(520-522)Cgc>Tgc	p.R174C	TTLL8_ENST00000440475.1_Missense_Mutation_p.R174C					tubulin tyrosine ligase-like family, member 8											NS(1)|haematopoietic_and_lymphoid_tissue(1)|lung(6)|ovary(4)	12		all_cancers(38;3.44e-07)|all_epithelial(38;2.44e-06)|all_lung(38;0.00141)|Breast(42;0.00519)|Lung NSC(38;0.0199)|Ovarian(80;0.142)|Lung SC(80;0.162)		READ - Rectum adenocarcinoma(2;0.000882)|Colorectal(2;0.00311)|BRCA - Breast invasive adenocarcinoma(115;0.226)		GCCATGGTGCGCCGGAAGTCT	0.657000													3	25					0	0	1	0	0
GGT3P	2679	broad.mit.edu	37	22	18769145	18769145	+	RNA	SNP	G	G	A			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr22:18769145G>A	ENST00000412448.1	-	0	1141																											TGAGGCTGCCGTTGTAGAAGG	0.612000													4	9					0	0	1	0	0
KMT2D	8085	broad.mit.edu	37	12	49418672	49418672	+	Missense_Mutation	SNP	A	A	C			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr12:49418672A>C	ENST00000301067.7	-	49	15841	c.15842T>G	c.(15841-15843)cTg>cGg	p.L5281R		NM_003482.3	NP_003473.3			lysine (K)-specific methyltransferase 2D																		GAAGAGTCGCAGCATGTCAGC	0.557000													3	12					0	0	1	0	0
LOC100294341	100294341	broad.mit.edu	37	17	43587569	43587569	+	RNA	SNP	G	G	C	rs149697015	by1000genomes	TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr17:43587569G>C	ENST00000253803.2	+	0	267				LRRC37A4P_ENST00000579913.1_RNA																							aactccgtctgaaaagaaaag	0.443000													3	30					0	0	1	0	0
CDC42BPG	55561	broad.mit.edu	37	11	64594255	64594255	+	Frame_Shift_Del	DEL	C	C	-			TCGA-XG-A823-01A-11D-A35I-08	TCGA-XG-A823-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc26cf35-440d-4367-b876-3284a7b2c268	192ad1c4-a0ee-4beb-9edf-86085f1b1356	g.chr11:64594255delC	ENST00000342711.5	-	35	4400	c.4401delG	c.(4399-4401)gafs	p.E1467fs		NM_017525.2	NP_059995.2	Q6DT37	MRCKG_HUMAN	CDC42 binding protein kinase gamma (DMPK-like)	1467					actin cytoskeleton reorganization|intracellular signal transduction	cell leading edge|centrosome	ATP binding|magnesium ion binding|protein binding|protein serine/threonine kinase activity|small GTPase regulator activity			central_nervous_system(1)|lung(3)	4						CTCGGCCCTTCTCTTCGGGAG	0.672													2	4	---	---	---	---