Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
LAMA3	3909	broad.mit.edu	37	18	21513897	21513897	+	Nonsense_Mutation	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr18:21513897C>T	ENST00000313654.9	+	67	9101	c.8860C>T	c.(8860-8862)Cag>Tag	p.Q2954*	LAMA3_ENST00000269217.6_Nonsense_Mutation_p.Q1345*|LAMA3_ENST00000399516.3_Nonsense_Mutation_p.Q2898*|LAMA3_ENST00000588770.1_3'UTR|LAMA3_ENST00000587184.1_Nonsense_Mutation_p.Q1289*	NM_198129.1	NP_937762.1	Q16787	LAMA3_HUMAN	laminin, alpha 3	2954					cell adhesion|epidermis development|hemidesmosome assembly|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development	laminin-1 complex	receptor binding|structural molecule activity			NS(2)|breast(4)|central_nervous_system(3)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(24)|lung(54)|ovary(8)|prostate(6)|skin(7)|urinary_tract(4)	128	all_cancers(21;7.81e-05)|all_epithelial(16;4.45e-07)|Lung NSC(20;0.00156)|all_lung(20;0.00508)|Colorectal(14;0.0202)|Ovarian(20;0.17)				Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	TCGTATCAACCAGGTAAGTGT	0.493000													11	60					0	0	1	0	0
FAM111B	374393	broad.mit.edu	37	11	58893249	58893249	+	Missense_Mutation	SNP	G	G	C			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr11:58893249G>C	ENST00000343597.3	+	4	1870	c.1679G>C	c.(1678-1680)gGa>gCa	p.G560A	FAM111B_ENST00000529618.1_Missense_Mutation_p.G530A|FAM111B_ENST00000411426.1_Missense_Mutation_p.G530A	NM_198947.3	NP_945185.1	Q6SJ93	F111B_HUMAN	family with sequence similarity 111, member B	560							catalytic activity			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(13)|liver(1)|lung(12)|ovary(3)|pancreas(1)|skin(1)	40						TTTCCTCCAGGACTATGGCGA	0.368000													12	119					0	0	1	0	0
ACADVL	37	broad.mit.edu	37	17	7126073	7126073	+	Silent	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr17:7126073G>A	ENST00000356839.5	+	10	1145	c.966G>A	c.(964-966)gtG>gtA	p.V322V	ACADVL_ENST00000543245.2_Silent_p.V345V|ACADVL_ENST00000350303.5_Silent_p.V300V	NM_000018.3|NM_001270448.1	NP_000009.1|NP_001257377.1	P49748	ACADV_HUMAN	acyl-CoA dehydrogenase, very long chain	322	Catalytic.				energy derivation by oxidation of organic compounds|fatty acid beta-oxidation using acyl-CoA dehydrogenase|negative regulation of fatty acid biosynthetic process|negative regulation of fatty acid oxidation|regulation of cholesterol metabolic process|temperature homeostasis	mitochondrial inner membrane|mitochondrial nucleoid	long-chain-acyl-CoA dehydrogenase activity			breast(2)|cervix(2)|endometrium(6)|kidney(1)|large_intestine(2)|liver(2)|lung(1)|ovary(4)|skin(1)	21						CGGAGAACGTGCTGGGTGAGG	0.562000													6	11					0	0	1	0	0
SPAG17	200162	broad.mit.edu	37	1	118567994	118567994	+	Missense_Mutation	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr1:118567994C>T	ENST00000336338.5	-	27	3841	c.3776G>A	c.(3775-3777)cGt>cAt	p.R1259H		NM_206996.2	NP_996879.1	Q6Q759	SPG17_HUMAN	sperm associated antigen 17	1259						cilium|flagellar axoneme|microtubule				NS(1)|biliary_tract(1)|breast(2)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(30)|liver(2)|lung(56)|ovary(3)|prostate(5)|skin(5)|upper_aerodigestive_tract(6)|urinary_tract(1)	123	Esophageal squamous(2;0.0106)	all_cancers(81;0.0204)|all_lung(203;9.46e-05)|Lung NSC(69;0.000675)|all_epithelial(167;0.01)		Lung(183;0.0858)		GTAGCTCTGACGGACCATGAT	0.483000													4	96					0	0	1	0	0
SNRNP48	154007	broad.mit.edu	37	6	7601689	7601689	+	Missense_Mutation	SNP	G	G	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr6:7601689G>T	ENST00000342415.5	+	5	586	c.527G>T	c.(526-528)cGc>cTc	p.R176L		NM_152551.3	NP_689764.3	Q6IEG0	SNR48_HUMAN	small nuclear ribonucleoprotein 48kDa (U11/U12)	176					mRNA processing	cytoplasm|U12-type spliceosomal complex	metal ion binding			kidney(2)|lung(5)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	10						AAGAAAAAGCGCTCTGATTCT	0.388000													5	86					3.59834e-05	4.00569e-05	1	1	0
PCDHB6	0	broad.mit.edu	37	5	140530650	140530650	+	Missense_Mutation	SNP	G	G	C			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr5:140530650G>C	ENST00000231136.1	+	1	812	c.812G>C	c.(811-813)gGa>gCa	p.G271A	PCDHB6_ENST00000543635.1_Missense_Mutation_p.G135A	NM_018939.2	NP_061762.1	Q9Y5E3	PCDB6_HUMAN		271	Cadherin 3.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to plasma membrane	calcium ion binding			cervix(1)|endometrium(14)|kidney(6)|large_intestine(16)|liver(1)|lung(33)|ovary(1)|pancreas(2)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	84			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			TTAGATGCAGGATCGTTTGGG	0.498000													5	67					0	0	1	0	0
ALPPL2	251	broad.mit.edu	37	2	233272008	233272008	+	Missense_Mutation	SNP	C	C	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr2:233272008C>G	ENST00000295453.3	+	3	249	c.197C>G	c.(196-198)tCt>tGt	p.S66C		NM_031313.2	NP_112603.2	P10696	PPBN_HUMAN	alkaline phosphatase, placental-like 2	66					phosphorylation	anchored to membrane|plasma membrane	alkaline phosphatase activity|metal ion binding			breast(2)|kidney(1)|large_intestine(1)|liver(2)|lung(6)|skin(1)	13		all_hematologic(139;0.00793)|Renal(207;0.0112)|Acute lymphoblastic leukemia(138;0.0182)|all_lung(227;0.0449)|Lung NSC(271;0.132)		Epithelial(121;4.45e-22)|Kidney(3;4.42e-11)|KIRC - Kidney renal clear cell carcinoma(3;1.9e-09)|BRCA - Breast invasive adenocarcinoma(100;0.000767)|Lung(119;0.00566)|LUSC - Lung squamous cell carcinoma(224;0.00746)|STAD - Stomach adenocarcinoma(3;0.0181)|GBM - Glioblastoma multiforme(43;0.196)	Amifostine(DB01143)|Levamisole(DB00848)	ATGGGGGTGTCTACGGTGACA	0.637000													3	54					0	0	1	0	0
ANKLE2	23141	broad.mit.edu	37	12	133304674	133304674	+	Silent	SNP	C	C	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr12:133304674C>A	ENST00000539605.1	-	11	9057	c.2373G>T	c.(2371-2373)ccG>ccT	p.P791P	ANKLE2_ENST00000542657.1_Silent_p.P208P|ANKLE2_ENST00000542282.1_Silent_p.P208P|ANKLE2_ENST00000357997.5_Silent_p.P853P|ANKLE2_ENST00000542374.1_5'UTR			Q86XL3	ANKL2_HUMAN	ankyrin repeat and LEM domain containing 2	853						cytoplasm|integral to membrane|nuclear envelope				NS(2)|autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(4)|kidney(3)|large_intestine(4)|lung(20)|ovary(1)|urinary_tract(2)	45	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.0176)|Lung NSC(355;0.204)		OV - Ovarian serous cystadenocarcinoma(86;2.3e-08)|Epithelial(86;1.56e-07)|all cancers(50;4.94e-06)		TGTGCACGGCCGGGAACTGAT	0.552000													10	145					7.48243e-07	8.82927e-07	1	1	0
TP53	7157	broad.mit.edu	37	17	7578272	7578272	+	Missense_Mutation	SNP	G	G	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr17:7578272G>T	ENST00000420246.2	-	6	709	c.577C>A	c.(577-579)Cat>Aat	p.H193N	TP53_ENST00000359597.4_Missense_Mutation_p.H193N|TP53_ENST00000445888.2_Missense_Mutation_p.H193N|TP53_ENST00000269305.4_Missense_Mutation_p.H193N|TP53_ENST00000574684.1_Intron|TP53_ENST00000413465.2_Missense_Mutation_p.H193N|TP53_ENST00000455263.2_Missense_Mutation_p.H193N	NM_001126114.2|NM_001276696.1	NP_001119586.1|NP_001263625.1	P04637	P53_HUMAN	tumor protein p53	193	Interaction with AXIN1 (By similarity).|Interaction with HIPK1 (By similarity).|Required for interaction with FBXO42.		H -> D (in sporadic cancers; somatic mutation).|H -> L (in sporadic cancers; somatic mutation).|H -> N (in sporadic cancers; somatic mutation).|H -> P (in sporadic cancers; somatic mutation).|H -> Q (in sporadic cancers; somatic mutation).|H -> R (in LFS; germline mutation and in sporadic cancers; somatic mutation).|H -> Y (in sporadic cancers; somatic mutation).|QH -> HN (in a sporadic cancer; somatic mutation).|QH -> HY (in a sporadic cancer; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.H193Y(29)|p.H193D(13)|p.0?(8)|p.?(6)|p.H193N(4)|p.A189_V197delAPPQHLIRV(4)|p.H193fs*16(3)|p.P191_E198>Q(3)|p.P191fs*53(2)|p.H61D(2)|p.H100D(2)|p.P191fs*15(1)|p.H61Y(1)|p.P191fs*6(1)|p.H100Y(1)|p.P98_E105>Q(1)|p.H193_I195delHLI(1)|p.P59_E66>Q(1)|p.H193_I195>AP(1)|p.A189fs*53(1)		NS(16)|adrenal_gland(37)|autonomic_ganglia(16)|biliary_tract(273)|bone(108)|breast(2530)|central_nervous_system(1264)|cervix(68)|endometrium(223)|eye(24)|fallopian_tube(1)|gastrointestinal_tract_(site_indeterminate)(1)|genital_tract(16)|haematopoietic_and_lymphoid_tissue(1301)|kidney(96)|large_intestine(5124)|liver(897)|lung(2388)|meninges(5)|oesophagus(1473)|ovary(1659)|pancreas(452)|penis(10)|peritoneum(33)|pituitary(4)|placenta(1)|pleura(3)|prostate(235)|salivary_gland(43)|skin(791)|small_intestine(14)|soft_tissue(220)|stomach(1158)|testis(11)|thymus(21)|thyroid(54)|upper_aerodigestive_tract(2271)|urinary_tract(1259)|vagina(6)|vulva(79)	24185		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		CGGATAAGATGCTGAGGAGGG	0.557000		111	"""Mis, N, F"""		"""breast, colorectal, lung, sarcoma, adrenocortical, glioma, multiple other tumour types"""	"""breast, sarcoma, adrenocortical carcinoma, glioma, multiple other tumour types"""		Other conserved DNA damage response genes	Osteosarcoma, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Breast-Ovarian Cancer, non-BRCA1/2;Hereditary Adrenocortical Cancer;Endometrial Cancer, Familial Clustering of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			13	6					0.000308642	0.000331089	1	1	0
TBC1D22B	55633	broad.mit.edu	37	6	37247120	37247120	+	Missense_Mutation	SNP	A	A	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr6:37247120A>G	ENST00000373491.3	+	3	300	c.154A>G	c.(154-156)Aag>Gag	p.K52E		NM_017772.2	NP_060242.2	Q9NU19	TB22B_HUMAN	TBC1 domain family, member 22B	52						intracellular	Rab GTPase activator activity			breast(1)|endometrium(1)|large_intestine(2)|lung(10)|prostate(1)	15			OV - Ovarian serous cystadenocarcinoma(102;0.241)			AGTTCCTCTGAAGAATAAGAA	0.428000													4	130					0	0	1	0	0
CNTNAP3	79937	broad.mit.edu	37	9	39178168	39178168	+	Missense_Mutation	SNP	A	A	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr9:39178168A>G	ENST00000297668.6	-	5	801	c.728T>C	c.(727-729)tTt>tCt	p.F243S	CNTNAP3_ENST00000377653.2_5'UTR|CNTNAP3_ENST00000377656.2_Missense_Mutation_p.F243S|CNTNAP3_ENST00000377659.1_Missense_Mutation_p.F243S|CNTNAP3_ENST00000358144.2_Missense_Mutation_p.F155S|CNTNAP3_ENST00000323947.7_Missense_Mutation_p.F243S	NM_033655.3	NP_387504.2	Q9BZ76	CNTP3_HUMAN	contactin associated protein-like 3	243	Laminin G-like 1.				cell adhesion|cell recognition|signal transduction	extracellular region|integral to membrane|plasma membrane	receptor binding			breast(1)|endometrium(3)|kidney(2)|large_intestine(5)|liver(2)|lung(8)|ovary(1)|upper_aerodigestive_tract(2)	24				GBM - Glioblastoma multiforme(29;0.02)|Lung(182;0.0681)		ATTAAGAAAAAAGACAAGCTT	0.299000													32	122					0	0	1	0	0
SOX30	11063	broad.mit.edu	37	5	157078493	157078493	+	Silent	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr5:157078493G>A	ENST00000265007.6	-	1	935	c.594C>T	c.(592-594)ggC>ggT	p.G198G	SOX30_ENST00000311371.5_Silent_p.G198G|SOX30_ENST00000519442.1_Intron	NM_178424.1	NP_848511.1	O94993	SOX30_HUMAN	SRY (sex determining region Y)-box 30	198					regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-dependent|response to corticosteroid stimulus|transcription, DNA-dependent	nucleus	sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity			central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(6)|lung(9)|ovary(1)|pancreas(1)|prostate(1)|urinary_tract(1)	23	Renal(175;0.00488)	Medulloblastoma(196;0.0354)|all_neural(177;0.138)	Kidney(164;0.000171)|KIRC - Kidney renal clear cell carcinoma(164;0.000785)			TGCCTGCCCCGCCTTGCATCG	0.657000													16	104					0	0	1	0	0
LL22NC03-80A10.6	0	broad.mit.edu	37	22	22662971	22662971	+	RNA	SNP	A	A	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr22:22662971A>G	ENST00000426066.1	+	0	500					NR_027293.1																						TGTAAGTAAAATTCACTTTGG	0.323000													2	5					0	0	1	0	0
MAPK8IP3	23162	broad.mit.edu	37	16	1774642	1774642	+	Nonsense_Mutation	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr16:1774642C>T	ENST00000250894.4	+	2	560	c.403C>T	c.(403-405)Cag>Tag	p.Q135*	MAPK8IP3_ENST00000356010.5_Nonsense_Mutation_p.Q135*	NM_015133.3	NP_055948.2	Q9UPT6	JIP3_HUMAN	mitogen-activated protein kinase 8 interacting protein 3	135					vesicle-mediated transport	Golgi membrane	kinesin binding|MAP-kinase scaffold activity|protein kinase binding			NS(1)|breast(3)|central_nervous_system(3)|cervix(1)|endometrium(3)|kidney(1)|large_intestine(2)|lung(20)|ovary(1)|prostate(2)|skin(2)|urinary_tract(3)	42						CCAGACGCGCCAGCTGGAGCT	0.557000													19	28					0	0	1	0	0
ARHGAP33	115703	broad.mit.edu	37	19	36269483	36269483	+	Missense_Mutation	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr19:36269483G>A	ENST00000007510.4	+	5	532	c.388G>A	c.(388-390)Gag>Aag	p.E130K	ARHGAP33_ENST00000378944.5_5'UTR|ARHGAP33_ENST00000314737.5_Missense_Mutation_p.E130K|ARHGAP33_ENST00000221905.1_3'UTR			O14559	RHG33_HUMAN	Rho GTPase activating protein 33	130	PX; atypical.				cell communication|protein transport|signal transduction	intracellular	GTPase activator activity|phosphatidylinositol binding|protein binding			endometrium(7)|large_intestine(8)|lung(13)|ovary(1)|pancreas(1)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	37						CCCGCCCCCCGAGGGTGCCAG	0.597000													10	32					0	0	1	0	0
KANSL1	284058	broad.mit.edu	37	17	44117079	44117079	+	Missense_Mutation	SNP	A	A	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr17:44117079A>G	ENST00000262419.6	-	8	2662	c.2192T>C	c.(2191-2193)cTa>cCa	p.L731P	KANSL1_ENST00000393476.3_Missense_Mutation_p.L88P|KANSL1_ENST00000432791.1_Missense_Mutation_p.L731P|KANSL1_ENST00000575318.1_Missense_Mutation_p.L731P|KANSL1_ENST00000574590.1_Missense_Mutation_p.L731P|KANSL1_ENST00000572904.1_Missense_Mutation_p.L731P	NM_001193466.1	NP_001180395.1	Q7Z3B3	K1267_HUMAN	KAT8 regulatory NSL complex subunit 1	731						MLL1 complex	protein binding										GGCTGTTGTTAGGAAGGAGCT	0.468000													28	62					0	0	1	0	0
MYH11	4629	broad.mit.edu	37	16	15841786	15841786	+	Missense_Mutation	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr16:15841786G>A	ENST00000338282.6	-	18	2301	c.2195C>T	c.(2194-2196)gCg>gTg	p.A732V	MYH11_ENST00000576790.1_Missense_Mutation_p.A732V|MYH11_ENST00000396324.3_Missense_Mutation_p.A739V|MYH11_ENST00000300036.5_Missense_Mutation_p.A732V|MYH11_ENST00000452625.2_Missense_Mutation_p.A739V	NM_022844.2	NP_074035.1	P35749	MYH11_HUMAN	myosin, heavy chain 11, smooth muscle	732	Myosin head-like.				axon guidance|cardiac muscle fiber development|elastic fiber assembly|skeletal muscle myosin thick filament assembly|smooth muscle contraction	cytosol|melanosome|muscle myosin complex|myosin filament	actin binding|ATP binding|calmodulin binding|motor activity|structural constituent of muscle			NS(2)|breast(7)|central_nervous_system(1)|endometrium(11)|kidney(5)|large_intestine(34)|liver(1)|lung(37)|ovary(9)|pancreas(1)|prostate(7)|skin(7)|upper_aerodigestive_tract(1)	123						GGCATTCGCCGCCAGGATCTC	0.612000			T	CBFB	AML								9	65					0	0	1	0	0
ADAMTS9	56999	broad.mit.edu	37	3	64666958	64666958	+	Missense_Mutation	SNP	G	G	C			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr3:64666958G>C	ENST00000498707.1	-	3	940	c.598C>G	c.(598-600)Caa>Gaa	p.Q200E	ADAMTS9_ENST00000295903.4_Missense_Mutation_p.Q200E|ADAMTS9_ENST00000459780.1_Missense_Mutation_p.Q200E	NM_182920.1	NP_891550.1	Q9P2N4	ATS9_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 9	200					glycoprotein catabolic process|multicellular organismal development|proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			breast(3)|central_nervous_system(4)|cervix(1)|endometrium(9)|kidney(4)|large_intestine(17)|liver(4)|lung(43)|ovary(3)|prostate(3)|skin(2)|stomach(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	100		Lung NSC(201;0.00682)		BRCA - Breast invasive adenocarcinoma(55;0.00142)|Kidney(15;0.00202)|KIRC - Kidney renal clear cell carcinoma(15;0.00221)		GGTTTGTTTTGTTCCTCTTCA	0.463000													16	32					0	0	1	0	0
TUBB8P7	0	broad.mit.edu	37	16	90161578	90161578	+	RNA	SNP	G	G	A	rs13337896	by1000genomes	TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr16:90161578G>A	ENST00000567960.1	+	0	314				TUBB8P7_ENST00000564451.1_RNA														p.R105H(3)									GCCAAGGGACGCTACACCGAA	0.587000													8	25					0	0	1	0	0
USP53	54532	broad.mit.edu	37	4	120192824	120192824	+	Missense_Mutation	SNP	A	A	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr4:120192824A>T	ENST00000450251.1	+	12	2353	c.1809A>T	c.(1807-1809)agA>agT	p.R603S	USP53_ENST00000274030.6_Missense_Mutation_p.R603S			Q70EK8	UBP53_HUMAN	ubiquitin specific peptidase 53	603					ubiquitin-dependent protein catabolic process		ubiquitin thiolesterase activity			breast(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(7)|lung(5)|ovary(1)|pancreas(1)|skin(2)|stomach(1)	27						GTGAAAAAAGACAGCATAGTC	0.363000													14	29					0	0	1	0	0
ZNF777	27153	broad.mit.edu	37	7	149152891	149152891	+	Missense_Mutation	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr7:149152891G>A	ENST00000247930.4	-	2	546	c.223C>T	c.(223-225)Ctc>Ttc	p.L75F		NM_015694.2	NP_056509.2	Q9ULD5	ZN777_HUMAN	zinc finger protein 777	75					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(5)|lung(17)|ovary(1)|skin(2)|urinary_tract(1)	26	Melanoma(164;0.165)		OV - Ovarian serous cystadenocarcinoma(82;0.00358)			CCCTTCTGGAGCACATGTGGC	0.587000													26	59					0	0	1	0	0
PCNT	5116	broad.mit.edu	37	21	47773070	47773070	+	Silent	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr21:47773070G>A	ENST00000359568.5	+	10	1616	c.1509G>A	c.(1507-1509)caG>caA	p.Q503Q	PCNT_ENST00000480896.1_3'UTR	NM_006031.5	NP_006022.3	O95613	PCNT_HUMAN	pericentrin	503	Glu-rich.				cilium assembly|G2/M transition of mitotic cell cycle	cytosol|microtubule	calmodulin binding			NS(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(15)|liver(2)|lung(41)|ovary(5)|pancreas(3)|prostate(3)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(2)	104	Breast(49;0.112)					ATTTAGAACAGCTGAAGCAGC	0.463000													16	38					0	0	1	0	0
LILRA3	0	broad.mit.edu	37	19	54804140	54804140	+	Splice_Site	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr19:54804140C>T	ENST00000391745.1	-	5	401	c.85_splice	c.e5+1	p.G29_splice	LILRA3_ENST00000251390.3_Splice_Site_p.G12_splice|LILRA3_ENST00000391744.3_Splice_Site_p.G12_splice					leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3											NS(3)|breast(1)|kidney(1)|large_intestine(3)|lung(12)|ovary(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	28	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(193;0.105)		CAAATCTCACCGAGACAGATC	0.592000													5	45					0	0	1	0	0
MUC2	4583	broad.mit.edu	37	11	1081442	1081442	+	Missense_Mutation	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr11:1081442C>T	ENST00000441003.2	+	12	1487	c.1460C>T	c.(1459-1461)cCg>cTg	p.P487L	MUC2_ENST00000359061.5_Missense_Mutation_p.P487L	NM_002457.2	NP_002448.2	Q02817	MUC2_HUMAN	mucin 2, oligomeric mucus/gel-forming	487	VWFD 2.					inner mucus layer|outer mucus layer	protein binding			NS(3)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(26)|haematopoietic_and_lymphoid_tissue(4)|kidney(11)|large_intestine(5)|lung(22)|ovary(2)|prostate(16)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	102		all_cancers(49;1.08e-07)|all_epithelial(84;5.08e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.191)		BRCA - Breast invasive adenocarcinoma(625;0.000207)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)	Pranlukast(DB01411)	GTCTTCCGCCCGTCTTCCTAC	0.652000													3	40					0	0	1	0	0
RP11-252A24.2	0	broad.mit.edu	37	16	74372644	74372644	+	RNA	SNP	A	A	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr16:74372644A>G	ENST00000429810.2	-	0	1552																											TACCCTTGTCAGGGGGAACAA	0.443000													3	16					0	0	1	0	0
HSD17B4	3295	broad.mit.edu	37	5	118865641	118865641	+	Missense_Mutation	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr5:118865641C>T	ENST00000504811.1	+	22	2079	c.1895C>T	c.(1894-1896)cCa>cTa	p.P632L	HSD17B4_ENST00000522415.1_3'UTR|HSD17B4_ENST00000515320.1_Missense_Mutation_p.P589L|HSD17B4_ENST00000510025.1_Missense_Mutation_p.P583L|HSD17B4_ENST00000513628.1_Missense_Mutation_p.P470L|HSD17B4_ENST00000256216.6_Missense_Mutation_p.P607L|HSD17B4_ENST00000509514.1_Missense_Mutation_p.P345L|HSD17B4_ENST00000414835.2_Missense_Mutation_p.P467L	NM_001199291.1	NP_001186220.1	P51659	DHB4_HUMAN	hydroxysteroid (17-beta) dehydrogenase 4	607	SCP2.				bile acid biosynthetic process|fatty acid beta-oxidation using acyl-CoA oxidase	peroxisomal matrix	3-hydroxyacyl-CoA dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity|estradiol 17-beta-dehydrogenase activity|isomerase activity|long-chain-enoyl-CoA hydratase activity|protein binding|sterol binding|sterol transporter activity			breast(2)|cervix(2)|endometrium(3)|kidney(1)|large_intestine(3)|lung(8)|ovary(1)|pancreas(1)|prostate(2)|urinary_tract(2)	25		all_cancers(142;0.0206)|Prostate(80;0.0322)		OV - Ovarian serous cystadenocarcinoma(64;0.000247)|Epithelial(69;0.000849)|all cancers(49;0.0122)	NADH(DB00157)	GATCTTGCACCAACATCTGGT	0.363000													10	117					0	0	1	0	0
IQCA1	79781	broad.mit.edu	37	2	237402438	237402438	+	Silent	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr2:237402438C>T	ENST00000409907.3	-	3	703	c.429G>A	c.(427-429)gcG>gcA	p.A143A	IQCA1_ENST00000431676.2_Silent_p.A143A|IQCA1_ENST00000309507.5_Silent_p.A139A			Q86XH1	IQCA1_HUMAN	IQ motif containing with AAA domain 1	143							ATP binding			cervix(1)|endometrium(3)|kidney(2)|large_intestine(7)|lung(12)|ovary(1)	26						TTCCGCTGTCCGCTAATATTT	0.333000													4	2					0	0	1	0	0
C2orf16	84226	broad.mit.edu	37	2	27799480	27799480	+	Missense_Mutation	SNP	A	A	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr2:27799480A>T	ENST00000408964.2	+	1	92	c.41A>T	c.(40-42)tAt>tTt	p.Y14F		NM_032266.3	NP_115642.3	Q68DN1	CB016_HUMAN	chromosome 2 open reading frame 16	14										breast(1)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(33)|urinary_tract(1)	47	Acute lymphoblastic leukemia(172;0.155)					GGTATAAATTATCAAGAGTTG	0.448000													5	57					0	0	1	0	0
KDM6A	7403	broad.mit.edu	37	X	44894231	44894231	+	Splice_Site	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chrX:44894231G>A	ENST00000377967.4	+	7	660		c.e7+1		KDM6A_ENST00000543216.1_Splice_Site|KDM6A_ENST00000382899.4_Splice_Site|KDM6A_ENST00000536777.1_Splice_Site	NM_021140.2	NP_066963.2	O15550	KDM6A_HUMAN	lysine (K)-specific demethylase 6A						histone H3-K4 methylation		metal ion binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	p.0(12)|p.0?(6)|p.?(2)		NS(1)|breast(7)|central_nervous_system(27)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(24)|kidney(24)|large_intestine(9)|liver(1)|lung(21)|oesophagus(11)|pancreas(2)|prostate(5)|skin(1)|soft_tissue(1)|urinary_tract(29)	170						AATGCTGAAAGTAAGTATTAT	0.328000			"""D, N, F, S"""		"""renal, oesophageal SCC, MM"""								5	46					0	0	1	0	0
GPR126	0	broad.mit.edu	37	6	142691610	142691610	+	Missense_Mutation	SNP	T	T	G			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr6:142691610T>G	ENST00000230173.6	+	4	1225	c.749T>G	c.(748-750)tTt>tGt	p.F250C	GPR126_ENST00000367609.3_Missense_Mutation_p.F250C|GPR126_ENST00000367608.2_Missense_Mutation_p.F250C|GPR126_ENST00000545477.1_Intron|GPR126_ENST00000296932.8_Missense_Mutation_p.F250C	NM_020455.5	NP_065188.4	Q86SQ4	GP126_HUMAN	G protein-coupled receptor 126	250	Pentaxin.				neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			cervix(1)|endometrium(1)|kidney(3)|large_intestine(12)|lung(10)|ovary(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	36	Breast(32;0.176)			OV - Ovarian serous cystadenocarcinoma(155;9.33e-06)|GBM - Glioblastoma multiforme(68;0.00121)		GCAGAAAGCTTTGAACAGCTC	0.338000													8	38					0	0	1	0	0
WASH3P	0	broad.mit.edu	37	15	102516424	102516424	+	RNA	SNP	G	G	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr15:102516424G>T	ENST00000557932.1	+	0	1372																		p.P449P(4)		central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						TGCCGCCACCGCAGCAGCCAC	0.647000													4	28					1.23904e-05	1.40583e-05	1	1	0
OR1N1	138883	broad.mit.edu	37	9	125288736	125288736	+	Silent	SNP	C	C	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr9:125288736C>A	ENST00000304880.2	-	1	836	c.837G>T	c.(835-837)gtG>gtT	p.V279V		NM_012363.1	NP_036495.1	Q8NGS0	OR1N1_HUMAN	olfactory receptor, family 1, subfamily N, member 1	279					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(2)|central_nervous_system(1)|large_intestine(2)|lung(6)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	15						ACATGGGAGTCACTATGGTGT	0.483000													34	64					2.85442e-18	3.43695e-18	1	1	0
GSDMA	284110	broad.mit.edu	37	17	38133155	38133155	+	Silent	SNP	C	C	T	rs138595723	by1000genomes	TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr17:38133155C>T	ENST00000301659.4	+	12	1300	c.1182C>T	c.(1180-1182)gaC>gaT	p.D394D		NM_178171.4	NP_835465.2	Q96QA5	GSDMA_HUMAN	gasdermin A	394					apoptosis|induction of apoptosis	perinuclear region of cytoplasm				NS(1)|endometrium(2)|large_intestine(3)|lung(1)	7						CCCTTGGGGACGAGGAGCTGA	0.597000													5	81					0	0	1	0	0
PCDHA5	0	broad.mit.edu	37	5	140203514	140203514	+	Silent	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr5:140203514C>T	ENST00000529859.1	+	1	2154	c.2154C>T	c.(2152-2154)acC>acT	p.T718T	PCDHA2_ENST00000526136.1_Intron|PCDHA3_ENST00000522353.2_Intron|PCDHA1_ENST00000504120.2_Intron|PCDHA1_ENST00000394633.3_Intron|PCDHA4_ENST00000530339.1_Intron|PCDHA5_ENST00000529619.1_Silent_p.T718T|PCDHA4_ENST00000512229.2_Intron|PCDHA5_ENST00000378126.3_Silent_p.T718T	NM_018908.2	NP_061731.1														NS(1)|autonomic_ganglia(1)|breast(2)|endometrium(4)|kidney(6)|large_intestine(8)|liver(1)|lung(22)|ovary(2)|prostate(6)|skin(4)|upper_aerodigestive_tract(3)	60			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			TGCTGTACACCGCGCTGCGGT	0.672000													7	51					0	0	1	0	0
TBP	6908	broad.mit.edu	37	6	170871052	170871052	+	Silent	SNP	G	G	A	rs112083427		TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr6:170871052G>A	ENST00000392092.2	+	3	507	c.228G>A	c.(226-228)caG>caA	p.Q76Q	TBP_ENST00000230354.6_Silent_p.Q76Q|TBP_ENST00000540980.1_Silent_p.Q56Q	NM_003194.4	NP_003185.1	P20226	TBP_HUMAN	TATA box binding protein	76	Poly-Gln.				cell death|interspecies interaction between organisms|transcription elongation from RNA polymerase II promoter|transcription from RNA polymerase III promoter|viral reproduction	transcription factor TFIIA complex|transcription factor TFIID complex	repressing transcription factor binding|transcription regulatory region DNA binding	p.Q76Q(4)		breast(2)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(2)|lung(9)|ovary(1)|prostate(4)|urinary_tract(1)	26		Breast(66;5.08e-05)|Ovarian(120;0.125)|Esophageal squamous(34;0.246)		OV - Ovarian serous cystadenocarcinoma(33;1.07e-22)|BRCA - Breast invasive adenocarcinoma(81;5.01e-06)|GBM - Glioblastoma multiforme(31;0.00591)		agcaacagcagcagcagcagc	0.572000													6	27					0	0	1	0	0
EEF1D	1936	broad.mit.edu	37	8	144672319	144672319	+	Missense_Mutation	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr8:144672319G>A	ENST00000532741.1	-	1	311	c.83C>T	c.(82-84)aCg>aTg	p.T28M	EEF1D_ENST00000423316.2_Intron|EEF1D_ENST00000529272.1_Intron|EEF1D_ENST00000531621.1_Intron|EEF1D_ENST00000419152.2_Intron|EEF1D_ENST00000524624.1_Intron|EEF1D_ENST00000317198.6_Intron|EEF1D_ENST00000526838.1_Intron|EEF1D_ENST00000528610.1_Intron|EEF1D_ENST00000395119.3_Intron|EEF1D_ENST00000532400.1_Intron|EEF1D_ENST00000442189.2_Intron			P29692	EF1D_HUMAN	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	0					positive regulation of I-kappaB kinase/NF-kappaB cascade	cytosol|eukaryotic translation elongation factor 1 complex	protein binding|signal transducer activity|translation elongation factor activity			breast(2)|cervix(1)|endometrium(1)|kidney(4)|lung(2)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	14	all_cancers(97;3.74e-11)|all_epithelial(106;2.62e-09)|Lung NSC(106;0.00013)|all_lung(105;0.000374)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		Colorectal(110;0.134)|BRCA - Breast invasive adenocarcinoma(115;0.239)			CCGCAGCCCCGTGCCCACCCT	0.667000													3	19					0	0	1	0	0
DIS3	22894	broad.mit.edu	37	13	73337651	73337651	+	Missense_Mutation	SNP	G	G	C			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr13:73337651G>C	ENST00000377767.4	-	16	2165	c.2065C>G	c.(2065-2067)Cga>Gga	p.R689G	DIS3_ENST00000377780.4_Missense_Mutation_p.R659G|DIS3_ENST00000545453.1_Missense_Mutation_p.R527G	NM_014953.3	NP_055768.3	Q9Y2L1	RRP44_HUMAN	DIS3 mitotic control homolog (S. cerevisiae)	689					CUT catabolic process|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|rRNA catabolic process|rRNA processing	cytosol|exosome (RNase complex)|nucleolus|nucleoplasm	3'-5'-exoribonuclease activity|endonuclease activity|guanyl-nucleotide exchange factor activity|protein binding|RNA binding			central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(7)|kidney(5)|large_intestine(10)|lung(6)|prostate(2)|skin(1)	35		Breast(118;0.0074)|Acute lymphoblastic leukemia(28;0.0195)		GBM - Glioblastoma multiforme(99;0.000181)		GGATGTTTTCGAAGCAGAGCA	0.368000										Multiple Myeloma(4;0.011)			16	46					0	0	1	0	0
ANO6	196527	broad.mit.edu	37	12	45816826	45816826	+	Missense_Mutation	SNP	C	C	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr12:45816826C>T	ENST00000320560.8	+	19	2709	c.2507C>T	c.(2506-2508)gCt>gTt	p.A836V	ANO6_ENST00000423947.3_Missense_Mutation_p.A857V|ANO6_ENST00000435642.1_Missense_Mutation_p.A836V|ANO6_ENST00000425752.2_Missense_Mutation_p.A836V|ANO6_ENST00000441606.2_Missense_Mutation_p.A818V	NM_001025356.2	NP_001020527.2	Q4KMQ2	ANO6_HUMAN	anoctamin 6	836					activation of blood coagulation via clotting cascade|phosphatidylserine exposure on blood platelet	chloride channel complex|plasma membrane	chloride channel activity			central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(8)|lung(23)|ovary(2)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	46						GCCAAGCTGGCTTTTATCATT	0.408000													5	89					0	0	1	0	0
KCNQ5	56479	broad.mit.edu	37	6	73787590	73787590	+	Missense_Mutation	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr6:73787590G>A	ENST00000342056.2	+	5	1296	c.898G>A	c.(898-900)Gat>Aat	p.D300N	KCNQ5_ENST00000403813.2_Missense_Mutation_p.D300N|KCNQ5_ENST00000402622.2_Missense_Mutation_p.D300N|KCNQ5_ENST00000370392.1_Missense_Mutation_p.D300N|KCNQ5_ENST00000370398.1_Missense_Mutation_p.D300N|KCNQ5_ENST00000355635.3_Missense_Mutation_p.D300N|KCNQ5_ENST00000355194.4_Missense_Mutation_p.D300N|KCNQ5_ENST00000414165.2_Missense_Mutation_p.D300N	NM_001160132.1|NM_001160133.1	NP_001153604.1|NP_001153605.1	Q9NR82	KCNQ5_HUMAN	potassium voltage-gated channel, KQT-like subfamily, member 5	300					protein complex assembly|synaptic transmission	voltage-gated potassium channel complex	inward rectifier potassium channel activity			breast(1)|cervix(1)|endometrium(6)|kidney(7)|large_intestine(13)|lung(15)|ovary(4)|pancreas(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	57		all_epithelial(107;0.116)|Lung NSC(302;0.219)		COAD - Colon adenocarcinoma(1;0.0107)|Colorectal(1;0.0583)		TACATATGCAGATGCTCTCTG	0.328000													24	51					0	0	1	0	0
ZNF586	54807	broad.mit.edu	37	19	58288003	58288003	+	Translation_Start_Site	SNP	G	G	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr19:58288003G>A	ENST00000391702.3	+	0	367				ZNF586_ENST00000396150.4_Intron|ZNF586_ENST00000396154.2_Silent_p.V43V|ZNF586_ENST00000598183.1_Intron|ZNF586_ENST00000598885.1_Intron|ZNF586_ENST00000599802.1_Intron	NM_001204814.1	NP_001191743.1	Q9NXT0	ZN586_HUMAN	zinc finger protein 586						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(6)|ovary(2)|prostate(1)	15		Colorectal(82;5.46e-05)|all_neural(62;0.0218)|Breast(46;0.0389)|Ovarian(87;0.0443)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.026)		ACCGTGACGTGATGCTGGAGA	0.473000													54	129					0	0	1	0	0
GABRA6	2559	broad.mit.edu	37	5	161119123	161119123	+	Missense_Mutation	SNP	G	G	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr5:161119123G>T	ENST00000523217.1	+	8	1215	c.973G>T	c.(973-975)Gcc>Tcc	p.A325S	GABRA6_ENST00000274545.5_Missense_Mutation_p.A335S	NM_000811.2	NP_000802.2	Q16445	GBRA6_HUMAN	gamma-aminobutyric acid (GABA) A receptor, alpha 6	335					gamma-aminobutyric acid signaling pathway	cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	benzodiazepine receptor activity|chloride channel activity			breast(1)|central_nervous_system(2)|endometrium(6)|large_intestine(9)|liver(2)|lung(22)|ovary(7)|skin(6)|urinary_tract(2)	57	Renal(175;0.00259)	Medulloblastoma(196;0.0208)|all_neural(177;0.0672)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)		Alprazolam(DB00404)|Ethchlorvynol(DB00189)|Flunitrazepam(DB01544)|Flurazepam(DB00690)|Lorazepam(DB00186)|Meprobamate(DB00371)|Midazolam(DB00683)	GACACAGAAGGCCAAAAGGAA	0.433000										TCGA Ovarian(5;0.080)			5	109					0.000602214	0.000634476	1	1	0
FMO3	2328	broad.mit.edu	37	1	171086373	171086373	+	Missense_Mutation	SNP	G	G	C			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr1:171086373G>C	ENST00000367755.4	+	9	1501	c.1390G>C	c.(1390-1392)Ggc>Cgc	p.G464R	FMO3_ENST00000392085.2_Missense_Mutation_p.G464R|FMO3_ENST00000538429.1_Missense_Mutation_p.G401R|FMO3_ENST00000542847.1_Missense_Mutation_p.G444R	NM_001002294.2	NP_001002294.1	P31513	FMO3_HUMAN	flavin containing monooxygenase 3	464					xenobiotic metabolic process	integral to membrane|intrinsic to endoplasmic reticulum membrane|microsome	flavin adenine dinucleotide binding|flavin-containing monooxygenase activity			endometrium(1)|kidney(1)|large_intestine(12)|lung(12)|skin(1)|stomach(2)|urinary_tract(2)	31	all_hematologic(923;0.0922)|Acute lymphoblastic leukemia(37;0.181)					AGTTTATTTTGGCCCTTGTAG	0.517000													7	47					0	0	1	0	0
TMEM102	284114	broad.mit.edu	37	17	7339883	7339883	+	Missense_Mutation	SNP	C	C	A			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr17:7339883C>A	ENST00000323206.1	+	3	858	c.585C>A	c.(583-585)agC>agA	p.S195R	RP11-104H15.9_ENST00000570444.1_RNA|RP11-104H15.7_ENST00000575310.1_RNA|TMEM102_ENST00000396568.1_Missense_Mutation_p.S195R	NM_178518.2	NP_848613.1	Q8N9M5	TM102_HUMAN	transmembrane protein 102	195					regulation of apoptosis|response to cytokine stimulus|signal transduction	cell surface|integral to membrane|intracellular	protein binding			kidney(1)|lung(3)|skin(1)	5		Prostate(122;0.173)				AGCCGCACAGCTACGTCACTG	0.577000													5	35					0.184627	0.187811	1	1	0
KALRN	8997	broad.mit.edu	37	3	124044870	124044870	+	Missense_Mutation	SNP	G	G	A	rs138101634		TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr3:124044870G>A	ENST00000360013.3	+	7	1257	c.1130G>A	c.(1129-1131)cGc>cAc	p.R377H	KALRN_ENST00000460856.1_Missense_Mutation_p.R377H|KALRN_ENST00000240874.3_Missense_Mutation_p.R377H	NM_001024660.3	NP_001019831.2	O60229	KALRN_HUMAN	kalirin, RhoGEF kinase	377					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|nervous system development|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|vesicle-mediated transport	actin cytoskeleton|cytosol	ATP binding|GTPase activator activity|metal ion binding|protein binding|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity			NS(1)|breast(1)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(21)|lung(28)|ovary(4)|prostate(5)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	83						GTGGCTTCCCGCCTCTCTGAG	0.547000													10	54					0	0	1	0	0
KANSL1	284058	broad.mit.edu	37	17	44117077	44117077	+	Missense_Mutation	SNP	T	T	C			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr17:44117077T>C	ENST00000262419.6	-	8	2664	c.2194A>G	c.(2194-2196)Aca>Gca	p.T732A	KANSL1_ENST00000393476.3_Missense_Mutation_p.T89A|KANSL1_ENST00000432791.1_Missense_Mutation_p.T732A|KANSL1_ENST00000575318.1_Missense_Mutation_p.T732A|KANSL1_ENST00000574590.1_Missense_Mutation_p.T732A|KANSL1_ENST00000572904.1_Missense_Mutation_p.T732A	NM_001193466.1	NP_001180395.1	Q7Z3B3	K1267_HUMAN	KAT8 regulatory NSL complex subunit 1	732						MLL1 complex	protein binding										CTGGCTGTTGTTAGGAAGGAG	0.478000													28	62					0	0	1	0	0
TRIM48	79097	broad.mit.edu	37	11	55032718	55032718	+	Missense_Mutation	SNP	G	G	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr11:55032718G>T	ENST00000417545.2	+	2	473	c.387G>T	c.(385-387)ttG>ttT	p.L129F		NM_024114.3	NP_077019.2	Q8IWZ4	TRI48_HUMAN	tripartite motif containing 48	113						intracellular	zinc ion binding			endometrium(13)|lung(19)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	38						TGCTCTGTTTGCTGTGCTCCA	0.527000													6	92					0.248553	0.248553	1	1	0
HSPD1P6	0	broad.mit.edu	37	3	36810380	36810381	+	RNA	INS	-	-	T			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr3:36810380_36810381insT	ENST00000424886.1	-	0	405_406																											TGAGTGAGGCCttttttttttt	0.540													3	5	---	---	---	---					
HGFAC	3083	broad.mit.edu	37	4	3446102	3446102	+	Frame_Shift_Del	DEL	C	C	-			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr4:3446102delC	ENST00000382774.3	+	6	778	c.663delC	c.(661-663)cgfs	p.R221fs	HGFAC_ENST00000511533.1_Frame_Shift_Del_p.R221fs	NM_001528.2	NP_001519.1	Q04756	HGFA_HUMAN	HGF activator	221	Fibronectin type-I.				proteolysis	extracellular space	protein binding|serine-type endopeptidase activity			central_nervous_system(3)|cervix(1)|endometrium(4)|large_intestine(2)|lung(8)|upper_aerodigestive_tract(2)|urinary_tract(2)	22				UCEC - Uterine corpus endometrioid carcinoma (64;0.163)		CCCGCGTGCGCCAGGGCCACG	0.672													2	4	---	---	---	---					
KCNN2	3781	broad.mit.edu	37	5	113698631	113698632	+	In_Frame_Ins	INS	-	-	GCC	rs34838882	by1000genomes	TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr5:113698631_113698632insGCC	ENST00000512097.3	+	2	1177_1178	c.159_160insGCC	c.(157-162)gcccgc>gcGCCccgc	p.53_54AR>APR	KCNN2_ENST00000264773.3_In_Frame_Ins_p.53_54AR>APR			Q9H2S1	KCNN2_HUMAN	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	53	Poly-Ala.					integral to membrane	calmodulin binding|small conductance calcium-activated potassium channel activity			breast(1)|endometrium(5)|kidney(2)|large_intestine(7)|lung(21)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	45		all_cancers(142;2.86e-05)|all_epithelial(76;9.33e-06)|Prostate(80;0.00955)|Ovarian(225;0.0444)|Breast(839;0.159)|Lung NSC(810;0.174)|all_lung(232;0.206)		OV - Ovarian serous cystadenocarcinoma(64;1.89e-08)|Epithelial(69;2.04e-08)|all cancers(49;3.74e-06)|COAD - Colon adenocarcinoma(37;0.142)|Colorectal(14;0.195)		CTGCAGCCGCTGCCGCCGCCGC	0.703													3	6	---	---	---	---					
PCP2	126006	broad.mit.edu	37	19	7697378	7697382	+	Frame_Shift_Del	DEL	GTCCA	GTCCA	-			TCGA-YL-A9WK-01A-11D-A377-08	TCGA-YL-A9WK-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0c0aa301-47a5-4e4f-bba7-2d4928ad174f	c1021edb-96b3-4849-9d2f-23a76cf0dd31	g.chr19:7697378_7697382delGTCCA	ENST00000311069.5	-	3	478_482	c.188_192delTGGAC	c.(187-192)afs	p.MD63fs	CTD-3214H19.4_ENST00000595866.1_Intron|PCP2_ENST00000598935.1_Frame_Shift_Del_p.MD47fs	NM_174895.1	NP_777555.1	Q8IVA1	PCP2_HUMAN	Purkinje cell protein 2	63	GoLoco 2.				signal transduction		GTPase activator activity			endometrium(1)|urinary_tract(1)	2						CCATGAGGCTGTCCATCTCGGGGGT	0.659													26	65	---	---	---	---