Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
TP63	0	genome.wustl.edu	37	3	189604233	189604233	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	3	189604233	189604233	A	G	SNP	TP63	ENST00000264731	human	ensembl	74_37	+1	known	missense	c.1400	p.N467S	1.000	NULL	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_SAM_2,superfamily_p53-like_TF_D-bd,superfamily_SAM/pointed,superfamily_p53_tetrameristn,smart_SAM,prints_p53_tumour_suppressor	-	no_errors	TP63	HGNC	ENSG00000073282	tier1	-	-	104	0	0.00	84	13	13.27	101	0	0.00	66	11	14.29
ST3GAL5	0	genome.wustl.edu	37	2	86090503	86090503	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	2	86090503	86090503	A	G	SNP	ST3GAL5	ENST00000377332	human	ensembl	74_37	-1	known	missense	c.188	p.L63S	0.979	pirsf_Sialyl_trans	pfam_Glyco_trans_29,pirsf_Sialyl_trans	-	no_errors	ST3GAL5	HGNC	ENSG00000115525	tier1	-	-	116	0	0.00	78	44	35.77	116	0	0.00	69	26	27.08
TDRD7	0	genome.wustl.edu	37	9	100235889	100235889	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	9	100235889	100235889	A	G	SNP	TDRD7	ENST00000355295	human	ensembl	74_37	+1	known	missense	c.2060	p.E687G	1.000	pfam_Tudor	pfam_Tudor,smart_Tudor,pfscan_Tudor	-	no_errors	TDRD7	HGNC	ENSG00000196116	tier1	-	-	77	0	0.00	87	20	18.69	137	0	0.00	91	26	22.22
SLC35G1	0	genome.wustl.edu	37	10	95658334	95658334	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	10	95658334	95658334	A	G	SNP	SLC35G1	ENST00000427197	human	ensembl	74_37	+1	known	missense	c.185	p.K62R	1.000	NULL	pfam_DMT	-	no_errors	SLC35G1	HGNC	ENSG00000176273	tier1	-	-	66	0	0.00	29	16	35.56	122	0	0.00	59	28	32.18
BPIFC	0	genome.wustl.edu	37	22	32843215	32843215	+	Missense_Mutation	SNP	A	A	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	22	32843215	32843215	A	T	SNP	BPIFC	ENST00000300399	human	ensembl	74_37	-1	known	missense	c.358	p.F120I	0.001	pfam_Lipid-bd_serum_glycop_N,superfamily_Bactericidal_perm-incr_a/b_dom,smart_Lipid-bd_serum_glycop_N	pfam_Lipid-bd_serum_glycop_N,pfam_Lipid-bd_serum_glycop_C,superfamily_Bactericidal_perm-incr_a/b_dom,smart_Lipid-bd_serum_glycop_N,smart_Lipid-bd_serum_glycop_C	-	no_errors	BPIFC	HGNC	ENSG00000184459	tier1	-	-	91	0	0.00	56	33	37.08	130	0	0.00	78	31	28.44
C20orf112	0	genome.wustl.edu	37	20	31099150	31099150	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	20	31099150	31099150	C	G	SNP	C20orf112	ENST00000201961	human	ensembl	74_37	-1	known	missense	c.417	p.Q139H	1.000	NULL	NULL	-	no_errors	C20orf112	HGNC	ENSG00000197183	tier1	-	-	81	0	0.00	61	19	23.75	63	0	0.00	52	11	17.46
PRH2	0	genome.wustl.edu	37	12	11082885	11082885	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	12	11082885	11082885	G	A	SNP	PRH2	ENST00000381847	human	ensembl	74_37	+1	known	missense	c.82	p.V28I	0.000	NULL	NULL	-	no_errors	PRH2	HGNC	ENSG00000134551	tier1	-	-	77	0	0.00	40	13	24.53	46	0	0.00	23	9	28.12
KLHDC7B	0	genome.wustl.edu	37	22	50986680	50986680	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	22	50986680	50986680	C	T	SNP	KLHDC7B	ENST00000395676	human	ensembl	74_37	+1	known	missense	c.85	p.P29S	0.004	NULL	pfam_Kelch_1,smart_Kelch_1	-	no_errors	KLHDC7B	HGNC	ENSG00000130487	tier1	-	-	88	0	0.00	58	26	30.95	50	0	0.00	21	12	36.36
ZNF607	0	genome.wustl.edu	37	19	38189646	38189646	+	Silent	SNP	T	T	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	19	38189646	38189646	T	C	SNP	ZNF607	ENST00000355202	human	ensembl	74_37	-1	known	silent	c.1386	p.S462	0.053	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF607	HGNC	ENSG00000198182	tier1	-	-	76	0	0.00	74	24	24.49	126	0	0.00	69	14	16.67
CEP290	0	genome.wustl.edu	37	12	88496697	88496697	+	Missense_Mutation	SNP	T	T	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	12	88496697	88496697	T	C	SNP	CEP290	ENST00000309041	human	ensembl	74_37	-1	known	missense	c.2915	p.N972S	1.000	NULL	NULL	-	no_errors	CEP290	HGNC	ENSG00000198707	tier1	-	-	88	0	0.00	51	25	32.89	113	0	0.00	54	27	33.33
ENSG00000262903	0	genome.wustl.edu	37	17	3560153	3560153	+	R	SNP	T	T	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	17	3560153	3560153	T	C	SNP	ENSG00000262903	ENST00000575741	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-235E17.6	Clone_based_vega_gene	ENSG00000262903	tier1	-	-	37	0	0.00	11	17	60.71	68	0	0.00	23	18	43.90
GBA	0	genome.wustl.edu	37	1	155206233	155206233	+	Missense_Mutation	SNP	A	A	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	1	155206233	155206233	A	T	SNP	GBA	ENST00000327247	human	ensembl	74_37	-1	known	missense	c.1027	p.Y343N	0.998	pfam_Glyco_hydro_30,superfamily_Glycoside_hydrolase_SF	pfam_Glyco_hydro_30,superfamily_Glycoside_hydrolase_SF,prints_Glyco_hydro_30	-	no_errors	GBA	HGNC	ENSG00000177628	tier1	-	-	113	0	0.00	63	27	30.00	60	0	0.00	27	15	35.71
GATA3	0	genome.wustl.edu	37	10	8105992	8105992	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	10	8105992	8105992	C	A	SNP	GATA3	ENST00000379328	human	ensembl	74_37	+1	known	missense	c.815	p.T272N	1.000	pfam_Znf_GATA,smart_Znf_GATA,pirsf_TF_GATA-1/2/3,pfscan_Znf_GATA,prints_Znf_GATA	pfam_Znf_GATA,smart_Znf_GATA,pirsf_TF_GATA-1/2/3,pfscan_Znf_GATA,prints_Znf_GATA	-	no_errors	GATA3	HGNC	ENSG00000107485	tier1	-	-	98	0	0.00	25	24	48.98	78	0	0.00	24	35	59.32
F2R	0	genome.wustl.edu	37	5	76028937	76028937	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	5	76028937	76028937	G	T	SNP	F2R	ENST00000319211	human	ensembl	74_37	+1	known	missense	c.887	p.C296F	0.757	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Thrmbn_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Thrmbn_rcpt,prints_GPCR_Rhodpsn,prints_Protea_act_rcpt	-	no_errors	F2R	HGNC	ENSG00000181104	tier1	-	-	57	0	0.00	59	27	31.40	62	0	0.00	54	8	12.90
OR6C1	0	genome.wustl.edu	37	12	55714741	55714741	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	12	55714741	55714741	C	T	SNP	OR6C1	ENST00000379668	human	ensembl	74_37	+1	known	missense	c.358	p.R120C	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6C1	HGNC	ENSG00000205330	tier1	rs143845104	-	92	0	0.00	63	32	33.68	52	0	0.00	22	6	21.43
CNN2	0	genome.wustl.edu	37	19	1036080	1036080	+	Silent	SNP	G	G	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	19	1036080	1036080	G	C	SNP	CNN2	ENST00000562958	human	ensembl	74_37	+1	novel	silent	c.405	p.G135	0.002	superfamily_CH-domain	pfam_Calponin_repeat,pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain,pfscan_Calponin_repeat,prints_SM22_calponin,prints_Calponin	-	no_errors	CNN2	HGNC	ENSG00000064666	tier1	-	-	64	0	0.00	66	12	15.19	30	0	0.00	37	7	15.91
TJP1	0	genome.wustl.edu	37	15	29996494	29996494	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	15	29996494	29996494	C	G	SNP	TJP1	ENST00000346128	human	ensembl	74_37	-1	known	missense	c.5084	p.S1695T	1.000	pfam_ZU5,smart_ZU5,pfscan_ZU5	pfam_PDZ,pfam_ZU5,pfam_GK/Ca_channel_bsu,pfam_SH3_2,superfamily_PDZ,superfamily_P-loop_NTPase,superfamily_SH3_domain,smart_PDZ,smart_GK/Ca_channel_bsu,smart_ZU5,pfscan_PDZ,pfscan_SH3_domain,pfscan_ZU5,pfscan_Guanylate_kin-like,prints_ZonOcculS1,prints_ZonOcculdens	-	no_errors	TJP1	HGNC	ENSG00000104067	tier1	-	-	49	0	0.00	49	8	14.04	148	0	0.00	95	28	22.58
FGF5	0	genome.wustl.edu	37	4	81209881	81209881	+	R	SNP	A	A	G			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	4	81209881	81209881	A	G	SNP	FGF5	ENST00000503413	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	FGF5	HGNC	ENSG00000138675	tier1	-	-	24	0	0.00	13	8	38.10	102	0	0.00	37	19	33.93
MUC17	0	genome.wustl.edu	37	7	100677114	100677114	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	7	100677114	100677114	C	A	SNP	MUC17	ENST00000306151	human	ensembl	74_37	+1	known	missense	c.2417	p.P806H	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_EG-like_dom,pfscan_SEA_dom	-	no_errors	MUC17	HGNC	ENSG00000169876	tier1	-	-	110	0	0.00	77	32	29.36	46	0	0.00	25	5	16.67
KIAA1211	0	genome.wustl.edu	37	4	57180682	57180682	+	Silent	SNP	C	C	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	4	57180682	57180682	C	T	SNP	KIAA1211	ENST00000504228	human	ensembl	74_37	+1	known	silent	c.1014	p.D338	0.000	NULL	NULL	-	no_errors	KIAA1211	HGNC	ENSG00000109265	tier1	-	-	37	0	0.00	17	5	21.74	3	0	0.00	10	3	23.08
C1orf173	0	genome.wustl.edu	37	1	75037267	75037267	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	1	75037267	75037267	G	C	SNP	C1orf173	ENST00000326665	human	ensembl	74_37	-1	known	missense	c.4127	p.S1376C	0.005	NULL	NULL	-	no_errors	C1orf173	HGNC	ENSG00000178965	tier1	-	-	34	0	0.00	24	15	37.50	110	0	0.00	61	24	28.24
CTN2	0	genome.wustl.edu	37	2	80816439	80816439	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	2	80816439	80816439	C	T	SNP	CTN2	ENST00000361291	human	ensembl	74_37	+1	known	missense	c.2120	p.A707V	1.000	pfam_Vinculin/catenin,superfamily_Vinculin/catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTN2	HGNC	ENSG00000066032	tier1	-	-	103	0	0.00	33	21	38.89	123	0	0.00	22	38	63.33
DIP2A	0	genome.wustl.edu	37	21	47924314	47924314	+	Silent	SNP	G	G	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	21	47924314	47924314	G	C	SNP	DIP2A	ENST00000318711	human	ensembl	74_37	+1	known	silent	c.699	p.V233	0.036	NULL	pfam_AMP-dep_Synth/Lig,pfam_DMAP1-bd	-	no_errors	DIP2A	HGNC	ENSG00000160305	tier1	-	-	85	0	0.00	82	22	21.15	81	0	0.00	66	20	23.26
PRMT2	0	genome.wustl.edu	37	21	48083368	48083368	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	21	48083368	48083368	G	A	SNP	PRMT2	ENST00000355680	human	ensembl	74_37	+1	known	missense	c.1171	p.G391S	0.995	pfam_Arg_MeTrfase	pfam_SH3_domain,pfam_Arg_MeTrfase,pfam_SH3_2,pfam_Small_mtfrase_dom,pfam_Ribosomal-L11_MeTrfase_PrmA,pfam_tR_Trfase_Trm5/Tyw2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain,prints_SH3_domain	-	no_errors	PRMT2	HGNC	ENSG00000160310	tier1	-	-	41	0	0.00	37	18	32.73	50	0	0.00	54	18	25.00
ATF6B	0	genome.wustl.edu	37	6	32095994	32095994	+	R	SNP	C	C	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	6	32095994	32095994	C	T	SNP	ATF6B	ENST00000468502	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	ATF6B	HGNC	ENSG00000213676	tier1	-	-	69	0	0.00	76	20	20.83	57	0	0.00	36	13	26.53
LOC100507002	0	genome.wustl.edu	37	17	63097118	63097118	+	R	SNP	C	C	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	17	63097118	63097118	C	A	SNP	LOC100507002	ENST00000582940	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.999	-	-	-	no_errors	RP11-160O5.1	Clone_based_vega_gene	ENSG00000263470	tier1	-	-	45	0	0.00	9	7	43.75	89	0	0.00	19	17	47.22
MAP1S	0	genome.wustl.edu	37	19	17838873	17838873	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	19	17838873	17838873	C	T	SNP	MAP1S	ENST00000324096	human	ensembl	74_37	+1	known	missense	c.2680	p.R894C	0.070	NULL	NULL	-	no_errors	MAP1S	HGNC	ENSG00000130479	tier1	-	-	63	0	0.00	107	19	15.08	11	0	0.00	15	3	16.67
SLCO1B1	0	genome.wustl.edu	37	12	21331641	21331641	+	Missense_Mutation	SNP	T	T	C			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	12	21331641	21331641	T	C	SNP	SLCO1B1	ENST00000256958	human	ensembl	74_37	+1	known	missense	c.613	p.S205P	0.090	pfam_OA_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO1B1	HGNC	ENSG00000134538	tier1	-	-	101	0	0.00	72	8	10.00	100	0	0.00	39	19	32.76
PDE4DIP	0	genome.wustl.edu	37	1	144856959	144856959	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	1	144856959	144856959	G	T	SNP	PDE4DIP	ENST00000369356	human	ensembl	74_37	-1	known	missense	c.6526	p.H2176N	0.985	NULL	pfam_Spindle_assoc,superfamily_ARM-type_fold	-	no_errors	PDE4DIP	HGNC	ENSG00000178104	tier1	-	-	525	0	0.00	410	62	13.11	52	0	0.00	24	6	20.00
ANP32BP1	0	genome.wustl.edu	37	15	75614908	75614908	+	R	SNP	G	G	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	15	75614908	75614908	G	A	SNP	ANP32BP1	ENST00000564205	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.170	-	-	-	no_errors	ANP32BP1	HGNC	ENSG00000259790	tier1	-	-	69	0	0.00	54	16	22.86	10	0	0.00	8	4	33.33
CORO7-PAM16	0	genome.wustl.edu	37	16	4411430	4411430	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	16	4411430	4411430	G	A	SNP	CORO7-PAM16	ENST00000572467	human	ensembl	74_37	-1	known	missense	c.1619	p.T540M	1.000	smart_WD40_repeat,pfscan_WD40_repeat_dom	pfam_DUF1900,pfam_WD40_repeat,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	CORO7-PAM16	HGNC	ENSG00000103426	tier1	rs200682379	GMAF=0.0005	133	0	0.00	75	40	34.78	12	0	0.00	6	2	25.00
NPAS3	0	genome.wustl.edu	37	14	34269971	34269971	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	14	34269971	34269971	G	A	SNP	NPAS3	ENST00000356141	human	ensembl	74_37	+1	known	missense	c.2458	p.A820T	0.998	NULL	pfam_PAS_fold_3,pfam_PAS_fold,superfamily_PAS,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,pfscan_PAS,pfscan_bHLH_dom	-	no_errors	NPAS3	HGNC	ENSG00000151322	tier1	-	-	22	0	0.00	21	5	19.23	5	0	0.00	4	2	33.33
PLEKHG5	0	genome.wustl.edu	37	1	6529183	6529188	+	In_Frame_Del	DEL	TCCTCC	TCCTCC	-			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	TCCTCC	TCCTCC	TCCTCC	-	TCCTCC	TCCTCC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	1	6529183	6529188	TCCTCC	-	DEL	PLEKHG5	ENST00000537245	human	ensembl	74_37	-1	known	in_frame_del	c.2405_2400	p.EE801in_frame_del	0.152:0.271:0.391:0.513:0.634:0.754	NULL	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PLEKHG5	HGNC	ENSG00000171680	tier1			5	0	0.00	5	4	44.44	5	0	0.00	5	4	44.44
TCIRG1	0	genome.wustl.edu	37	11	67818126	67818126	+	Silent	SNP	G	G	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	11	67818126	67818126	G	A	SNP	TCIRG1	ENST00000265686	human	ensembl	74_37	+1	known	silent	c.2409	p.L803	1.000	pfam_V-ATPase_116kDa_su	pfam_V-ATPase_116kDa_su	-	no_errors	TCIRG1	HGNC	ENSG00000110719	tier1	-	-	85	0	0.00	45	4	8.16	28	0	0.00	7	0	0.00
TNRC18	0	genome.wustl.edu	37	7	5430009	5430011	+	In_Frame_Del	DEL	AAG	AAG	-			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	AAG	AAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	7	5430009	5430011	AAG	-	DEL	TNRC18	ENST00000399434	human	ensembl	74_37	-1	putative	in_frame_del	c.372_370	p.L124in_frame_del	0.694:0.670:0.633	NULL	NULL	-	no_errors	TNRC18	HGNC	ENSG00000182095	tier1			29	0	0.00	32	4	11.11	5	0	0.00	0	0	0.00
EOMES	0	genome.wustl.edu	37	3	27763427	27763428	+	In_Frame_Ins	INS	-	-	CGGCGC			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	3	27763427	27763428	-	CGGCGC	INS	EOMES	ENST00000449599	human	ensembl	74_37	-1	known	in_frame_ins	c.359_358	p.120in_frame_insGA	0.116:0.075	NULL	pfam_TF_T-box,superfamily_p53-like_TF_D-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box	-	no_errors	EOMES	HGNC	ENSG00000163508	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ESPNP	0	genome.wustl.edu	37	1	17026022	17026024	+	R	DEL	GGC	GGC	-			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	GGC	GGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	1	17026022	17026024	GGC	-	DEL	ESPNP	ENST00000492551	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000:1.000:0.992	-	-	-	no_errors	ESPNP	HGNC	ENSG00000268869	tier1			19	0	0.00	21	2	8.70	0	0	0.00	0	0	0.00
MRPL42	0	genome.wustl.edu	37	12	93894747	93894748	+	R	INS	-	-	A			TCGA-3B-A9HR-01A-11D-A387-09	TCGA-3B-A9HR-10A-01D-A38A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4355e545-4c5a-46c9-9bfa-a862afc22ae2	f3905e19-7e5a-43f6-8bd5-778ea63193c5	12	93894747	93894748	-	A	INS	MRPL42	ENST00000552938	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.002:0.008	-	-	-	no_errors	MRPL42	HGNC	ENSG00000198015	tier1			12	0	0.00	12	3	20.00	0	0	0.00	0	0	0.00