Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
RGS6	0	genome.wustl.edu	37	14	72943466	72943466	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	14	72943466	72943466	C	A	SNP	RGS6	ENST00000553525	human	ensembl	74_37	+1	known	missense	c.710	p.T237N	0.862	NULL	pfam_RGS_dom,pfam_G-protein_gamma-like_dom,pfam_DEP_dom,superfamily_Regulat_G_prot_signal_superfam,superfamily_G-protein_gamma-like_dom,smart_DEP_dom,smart_G-protein_gamma-like_dom,smart_Regulat_G_prot_signal_superfam,pfscan_DEP_dom,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS6	HGNC	ENSG00000182732	tier1	-	-	42	0	0.00	20	7	25.93	82	0	0.00	58	10	14.71
RNF213	0	genome.wustl.edu	37	17	78338308	78338308	+	Silent	SNP	C	C	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	17	78338308	78338308	C	G	SNP	RNF213	ENST00000582970	human	ensembl	74_37	+1	known	silent	c.11826	p.P3942	0.037	NULL	superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF213	HGNC	ENSG00000173821	tier1	-	-	26	0	0.00	15	6	28.57	67	0	0.00	31	11	26.19
LRP2	0	genome.wustl.edu	37	2	170028641	170028641	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	2	170028641	170028641	T	A	SNP	LRP2	ENST00000263816	human	ensembl	74_37	-1	known	missense	c.11147	p.E3716V	0.097	superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,superfamily_TIL_dom,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP2	HGNC	ENSG00000081479	tier1	-	-	41	0	0.00	42	11	20.75	76	0	0.00	38	15	28.30
EPHA7	0	genome.wustl.edu	37	6	93953228	93953228	+	Silent	SNP	A	A	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	6	93953228	93953228	A	G	SNP	EPHA7	ENST00000369303	human	ensembl	74_37	-1	known	silent	c.2913	p.V971	1.000	pirsf_Tyr_kinase_ephrin_rcpt,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_SAM,pfscan_SAM	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom	-	no_errors	EPHA7	HGNC	ENSG00000135333	tier1	-	-	45	0	0.00	36	9	20.00	97	0	0.00	46	21	31.34
CCDC51	0	genome.wustl.edu	37	3	48475279	48475279	+	Silent	SNP	A	A	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	48475279	48475279	A	G	SNP	CCDC51	ENST00000395694	human	ensembl	74_37	-1	known	silent	c.315	p.A105	0.764	NULL	NULL	-	no_errors	CCDC51	HGNC	ENSG00000164051	tier1	-	-	32	0	0.00	17	22	56.41	84	0	0.00	44	76	63.33
ANK1	0	genome.wustl.edu	37	8	41580669	41580669	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	8	41580669	41580669	C	T	SNP	ANK1	ENST00000396942	human	ensembl	74_37	-1	known	missense	c.883	p.G295R	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt	-	no_errors	ANK1	HGNC	ENSG00000029534	tier1	-	-	58	0	0.00	53	37	41.11	108	0	0.00	47	99	67.81
DPP6	0	genome.wustl.edu	37	7	154002609	154002609	+	Silent	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	7	154002609	154002609	G	A	SNP	DPP6	ENST00000332007	human	ensembl	74_37	+1	known	silent	c.30	p.S10	0.717	NULL	pfam_Peptidase_S9B,pfam_Peptidase_S9,pfam_PD40	-	no_errors	DPP6	HGNC	ENSG00000130226	tier1	-	-	46	0	0.00	33	8	19.05	68	0	0.00	36	6	14.29
CA5B	0	genome.wustl.edu	37	X	15790632	15790632	+	Silent	SNP	A	A	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	X	15790632	15790632	A	G	SNP	CA5B	ENST00000318636	human	ensembl	74_37	+1	known	silent	c.354	p.G118	0.993	pfam_Carbonic_anhydrase_a,superfamily_Carbonic_anhydrase_a,pfscan_Carbonic_anhydrase_a	pfam_Carbonic_anhydrase_a,superfamily_Carbonic_anhydrase_a,pfscan_Carbonic_anhydrase_a	-	no_errors	CA5B	HGNC	ENSG00000169239	tier1	-	-	73	0	0.00	39	28	41.79	99	0	0.00	49	36	42.35
TPMT	0	genome.wustl.edu	37	6	18130957	18130957	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	6	18130957	18130957	T	C	SNP	TPMT	ENST00000309983	human	ensembl	74_37	-1	known	missense	c.680	p.H227R	0.713	pfam_TPMT,pirsf_Thiopurine_S-MeTrfase	pfam_TPMT,pirsf_Thiopurine_S-MeTrfase	-	no_errors	TPMT	HGNC	ENSG00000137364	tier1	-	-	48	0	0.00	27	14	34.15	40	0	0.00	15	18	54.55
SMCO3	0	genome.wustl.edu	37	12	14959393	14959393	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	12	14959393	14959393	C	T	SNP	SMCO3	ENST00000316048	human	ensembl	74_37	-1	known	missense	c.222	p.M74I	0.000	NULL	NULL	-	no_errors	SMCO3	HGNC	ENSG00000179256	tier1	-	-	105	0	0.00	85	17	16.67	87	0	0.00	72	14	16.28
FMN2	0	genome.wustl.edu	37	1	240370168	240370168	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	1	240370168	240370168	C	A	SNP	FMN2	ENST00000319653	human	ensembl	74_37	+1	known	missense	c.2056	p.L686M	1.000	NULL	pfam_FH2_Formin,pfam_Formin_homology_1,smart_FH2_Formin,pfscan_DEP_dom	-	no_errors	FMN2	HGNC	ENSG00000155816	tier1	-	-	44	0	0.00	33	6	15.38	104	1	0.95	53	11	17.19
PTAR1	0	genome.wustl.edu	37	9	72338327	72338327	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	9	72338327	72338327	G	C	SNP	PTAR1	ENST00000340434	human	ensembl	74_37	-1	known	missense	c.862	p.L288V	1.000	NULL	pfam_Prenyl_trans_a,pfscan_Prenyl_trans_a	-	no_errors	PTAR1	HGNC	ENSG00000188647	tier1	-	-	81	0	0.00	61	9	12.86	95	0	0.00	87	17	16.35
OR9G4	0	genome.wustl.edu	37	11	56510497	56510497	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	11	56510497	56510497	A	T	SNP	OR9G4	ENST00000302957	human	ensembl	74_37	-1	known	missense	c.791	p.M264K	0.092	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR9G4	HGNC	ENSG00000172457	tier1	-	-	45	0	0.00	33	11	25.00	60	0	0.00	31	6	16.22
SLC4A8	0	genome.wustl.edu	37	12	51864185	51864185	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	12	51864185	51864185	G	C	SNP	SLC4A8	ENST00000453097	human	ensembl	74_37	+1	known	missense	c.1534	p.E512Q	1.000	pfam_HCO3_transpt_C,tigrfam_HCO3_transpt_euk	pfam_HCO3_transpt_C,pfam_Band3_cytoplasmic_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk,prints_Na/HCO3_transpt,tigrfam_HCO3_transpt_euk	-	no_errors	SLC4A8	HGNC	ENSG00000050438	tier1	-	-	105	0	0.00	1731	287	14.22	110	0	0.00	1909	320	14.32
SCN8A	0	genome.wustl.edu	37	12	52201083	52201083	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	12	52201083	52201083	C	T	SNP	SCN8A	ENST00000354534	human	ensembl	74_37	+1	known	missense	c.5813	p.T1938I	1.000	NULL	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,pfam_IQ_motif_EF-hand-BS,smart_IQ_motif_EF-hand-BS,prints_Na_channel_a8su,prints_Na_channel_asu,prints_PKD_2,pfscan_IQ_motif_EF-hand-BS	-	no_errors	SCN8A	HGNC	ENSG00000196876	tier1	-	-	20	0	0.00	42	22	34.38	123	0	0.00	230	98	29.79
RSBN1L	0	genome.wustl.edu	37	7	77398005	77398005	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	7	77398005	77398005	A	T	SNP	RSBN1L	ENST00000334955	human	ensembl	74_37	+1	known	missense	c.1510	p.S504C	1.000	NULL	NULL	-	no_errors	RSBN1L	HGNC	ENSG00000187257	tier1	-	-	61	0	0.00	27	5	15.62	51	0	0.00	41	6	12.77
ARMCX4	0	genome.wustl.edu	37	X	100746799	100746799	+	Nonsense_Mutation	SNP	G	G	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	X	100746799	100746799	G	T	SNP	ARMCX4	ENST00000423738	human	ensembl	74_37	+1	putative	nonsense	c.3223	p.E1075*	0.025	NULL	pfam_ARM-rpt_dom,superfamily_ARM-type_fold,pfscan_Armadillo	-	no_errors	ARMCX4	HGNC	ENSG00000196440	tier1	-	-	57	0	0.00	37	20	35.09	56	0	0.00	26	9	25.71
LPHN2	0	genome.wustl.edu	37	1	82416080	82416080	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	1	82416080	82416080	G	A	SNP	LPHN2	ENST00000370717	human	ensembl	74_37	+1	known	missense	c.1406	p.C469Y	1.000	pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom	pfam_GPCR_2_latrophilin_rcpt_C,pfam_Olfac-like,pfam_DUF3497,pfam_GPCR_2_secretin-like,pfam_Lectin_gal-bd_dom,pfam_GPS_dom,pfam_GPCR_2_extracellular_dom,smart_Olfac-like,smart_GPCR_2_extracellular_dom,smart_GPS_dom,prints_GPCR_2_latrophilin,prints_GPCR_2_secretin-like,pfscan_GPS_dom,pfscan_Lectin_gal-bd_dom,pfscan_Olfac-like,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like	-	no_errors	LPHN2	HGNC	ENSG00000117114	tier1	-	-	30	0	0.00	18	9	33.33	101	0	0.00	57	43	43.00
QARS	0	genome.wustl.edu	37	3	49136973	49136973	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	49136973	49136973	A	C	SNP	QARS	ENST00000306125	human	ensembl	74_37	-1	known	missense	c.1496	p.I499S	1.000	pfam_Glu/Gln-tR-synth_Ib_cat-dom,tigrfam_Gln-tR-synth	pfam_Glu/Gln-tR-synth_Ib_cat-dom,pfam_Gln-tR-synth_Ib_R-bd_N,pfam_Glu/Gln-tR-synth_Ib_codon-bd,pfam_Gln-tR-synth_Ib_R-bd_2,superfamily_Ribosomal_L25/Gln-tR_synth,prints_Glu/Gln-tR-synth,tigrfam_Gln-tR-synth	-	no_errors	QARS	HGNC	ENSG00000172053	tier1	-	-	56	0	0.00	59	13	18.06	86	0	0.00	58	29	33.33
GRIPAP1	0	genome.wustl.edu	37	X	48847665	48847665	+	R	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	X	48847665	48847665	G	A	SNP	GRIPAP1	ENST00000473581	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	GRIPAP1	HGNC	ENSG00000068400	tier1	-	-	15	0	0.00	0	9	100.00	97	0	0.00	74	40	35.09
UPF3A	0	genome.wustl.edu	37	13	115048329	115048329	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	13	115048329	115048329	A	T	SNP	UPF3A	ENST00000375299	human	ensembl	74_37	+1	known	missense	c.332	p.Y111F	1.000	pfam_Nonsense_mediated_decay_UPF3	pfam_Nonsense_mediated_decay_UPF3	-	no_errors	UPF3A	HGNC	ENSG00000169062	tier1	-	-	50	0	0.00	22	14	38.89	44	0	0.00	14	18	56.25
HSPA4L	0	genome.wustl.edu	37	4	128726313	128726313	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	4	128726313	128726313	C	G	SNP	HSPA4L	ENST00000439123	human	ensembl	74_37	+1	known	missense	c.1164	p.F388L	1.000	pfam_Hsp_70_fam,pfam_MreB_Mrl	pfam_Hsp_70_fam,pfam_MreB_Mrl,prints_Hsp_70_fam	-	no_errors	HSPA4L	HGNC	ENSG00000164070	tier1	-	-	38	0	0.00	33	4	10.81	116	0	0.00	62	12	16.22
POTEJ	0	genome.wustl.edu	37	2	131414229	131414229	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	2	131414229	131414229	C	A	SNP	POTEJ	ENST00000409602	human	ensembl	74_37	+1	novel	missense	c.1896	p.S632R	0.003	NULL	pfam_Actin-related,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Actin-related,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Actin-related	-	no_errors	POTEJ	HGNC	ENSG00000222038	tier1	-	-	294	0	0.00	242	43	15.09	55	0	0.00	42	7	14.29
TRPM2	0	genome.wustl.edu	37	21	45784082	45784082	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	21	45784082	45784082	G	A	SNP	TRPM2	ENST00000300482	human	ensembl	74_37	+1	known	missense	c.340	p.D114N	1.000	NULL	pfam_Ion_trans_dom,superfamily_NUDIX_hydrolase_dom-like	-	no_errors	TRPM2	HGNC	ENSG00000142185	tier1	-	-	34	0	0.00	28	11	28.21	126	0	0.00	37	19	33.93
FAM185A	0	genome.wustl.edu	37	7	102392177	102392177	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	7	102392177	102392177	G	A	SNP	FAM185A	ENST00000413034	human	ensembl	74_37	+1	known	missense	c.490	p.V164I	0.998	NULL	NULL	-	no_errors	FAM185A	HGNC	ENSG00000222011	tier1	-	-	48	0	0.00	29	23	43.40	105	0	0.00	52	38	42.22
RAD9A	0	genome.wustl.edu	37	11	67165480	67165480	+	R	SNP	C	C	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	11	67165480	67165480	C	G	SNP	RAD9A	ENST00000535644	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	RAD9A	HGNC	ENSG00000172613	tier1	-	-	27	0	0.00	17	6	26.09	111	0	0.00	52	28	34.57
SLC44A4	0	genome.wustl.edu	37	6	31831505	31831505	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	6	31831505	31831505	T	A	SNP	SLC44A4	ENST00000229729	human	ensembl	74_37	-1	known	missense	c.2032	p.N678Y	1.000	pfam_Choline_transptr-like	pfam_Choline_transptr-like	-	no_errors	SLC44A4	HGNC	ENSG00000204385	tier1	-	-	24	0	0.00	15	6	28.57	56	0	0.00	22	27	55.10
INPP5B	0	genome.wustl.edu	37	1	38343971	38343971	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	1	38343971	38343971	C	T	SNP	INPP5B	ENST00000373023	human	ensembl	74_37	-1	known	nonsense	c.1806	p.W602*	1.000	pfam_Endo/exonuclease/phosphatase,superfamily_Endo/exonuclease/phosphatase,smart_IPPc	pfam_Endo/exonuclease/phosphatase,pfam_RhoGAP_dom,superfamily_Endo/exonuclease/phosphatase,superfamily_Rho_GTPase_activation_prot,smart_IPPc,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	INPP5B	HGNC	ENSG00000204084	tier1	-	-	61	0	0.00	41	25	37.88	65	0	0.00	30	49	62.03
SCAF4	0	genome.wustl.edu	37	21	33073436	33073436	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	21	33073436	33073436	G	A	SNP	SCAF4	ENST00000286835	human	ensembl	74_37	-1	known	missense	c.649	p.P217S	1.000	NULL	pfam_R_pol_II-bd,pfam_RRM_dom,superfamily_ENTH_VHS,smart_CID_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	SCAF4	HGNC	ENSG00000156304	tier1	-	-	82	0	0.00	26	41	61.19	87	0	0.00	28	32	52.46
DPP4	0	genome.wustl.edu	37	2	162851506	162851506	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	2	162851506	162851506	C	A	SNP	DPP4	ENST00000360534	human	ensembl	74_37	-1	known	missense	c.2164	p.A722S	1.000	pfam_Peptidase_S9	pfam_Peptidase_S9B,pfam_Peptidase_S9	-	no_errors	DPP4	HGNC	ENSG00000197635	tier1	-	-	39	0	0.00	32	6	15.79	95	0	0.00	78	18	18.75
CAC1B	0	genome.wustl.edu	37	9	140852103	140852103	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	9	140852103	140852103	G	C	SNP	CAC1B	ENST00000371355	human	ensembl	74_37	+1	known	missense	c.1300	p.E434Q	1.000	NULL	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,pfscan_EF_hand_dom,prints_VDCCAlpha1,prints_VDCC_N_a1su,prints_PKD_2	-	no_errors	CAC1B	HGNC	ENSG00000148408	tier1	-	-	37	0	0.00	55	6	9.84	45	0	0.00	35	4	10.26
RNF128	0	genome.wustl.edu	37	X	105970351	105970351	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	X	105970351	105970351	G	A	SNP	RNF128	ENST00000255499	human	ensembl	74_37	+1	known	missense	c.208	p.V70M	1.000	NULL	pfam_Protease-assoc_domain,pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF128	HGNC	ENSG00000133135	tier1	-	-	60	0	0.00	15	34	69.39	33	0	0.00	11	17	60.71
ICA1	0	genome.wustl.edu	37	7	8196730	8196730	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	7	8196730	8196730	C	T	SNP	ICA1	ENST00000407906	human	ensembl	74_37	-1	putative	missense	c.820	p.G274R	0.000	NULL	pfam_AH_dom,pfscan_AH_dom	-	no_errors	ICA1	HGNC	ENSG00000003147	tier1	-	-	88	0	0.00	30	33	52.38	114	0	0.00	53	64	54.70
SKIL	0	genome.wustl.edu	37	3	170108927	170108927	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	170108927	170108927	G	C	SNP	SKIL	ENST00000259119	human	ensembl	74_37	+1	known	missense	c.1775	p.R592T	1.000	NULL	pfam_c-SKI_SMAD4-bd_dom,pfam_Transform_Ski,superfamily_SAND_dom-like,superfamily_D-bd_dom_put	-	no_errors	SKIL	HGNC	ENSG00000136603	tier1	-	-	31	0	0.00	18	7	28.00	78	0	0.00	32	8	20.00
FAM135B	0	genome.wustl.edu	37	8	139209759	139209759	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	8	139209759	139209759	C	A	SNP	FAM135B	ENST00000395297	human	ensembl	74_37	-1	known	nonsense	c.823	p.E275*	1.000	NULL	pfam_DUF676_lipase-like,pfam_DUF3657,pfam_PGAP1-like	-	no_errors	FAM135B	HGNC	ENSG00000147724	tier1	-	-	35	0	0.00	23	11	32.35	30	0	0.00	30	5	14.29
ZNF100	0	genome.wustl.edu	37	19	21909701	21909701	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	19	21909701	21909701	T	G	SNP	ZNF100	ENST00000358296	human	ensembl	74_37	-1	known	missense	c.1413	p.Q471H	0.001	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF100	HGNC	ENSG00000197020	tier1	-	-	47	0	0.00	85	18	17.48	10	0	0.00	10	8	44.44
NISCH	0	genome.wustl.edu	37	3	52505830	52505831	+	Frame_Shift_Del	DEL	GA	GA	-			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	GA	GA	GA	-	GA	GA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	52505830	52505831	GA	-	DEL	NISCH	ENST00000345716	human	ensembl	74_37	+1	known	frame_shift_del	c.410_411	p.E138fs	1.000:0.933	NULL	pfam_Phox,pfam_Leu-rich_rpt,superfamily_Phox,smart_Phox,pfscan_Phox	-	no_errors	NISCH	HGNC	ENSG00000010322	tier1			133	0	0.00	68	38	35.85	32	0	0.00	12	17	58.62
CCDC74A	0	genome.wustl.edu	37	2	132285768	132285768	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	2	132285768	132285768	C	G	SNP	CCDC74A	ENST00000295171	human	ensembl	74_37	+1	known	missense	c.225	p.I75M	0.993	NULL	NULL	-	no_errors	CCDC74A	HGNC	ENSG00000163040	tier1	-	-	68	0	0.00	45	14	23.73	9	0	0.00	5	6	54.55
NEB	0	genome.wustl.edu	37	2	152463201	152463201	+	Silent	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	2	152463201	152463201	G	A	SNP	NEB	ENST00000397345	human	ensembl	74_37	-1	known	silent	c.12666	p.D4222	0.886	pfam_Nebulin_35r-motif,smart_Nebulin_35r-motif,pfscan_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_Adhesion_dom,superfamily_6-PGluconate_DH_C-like,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_Nebulin	-	no_errors	NEB	HGNC	ENSG00000183091	tier1	-	-	148	0	0.00	22	116	84.06	26	0	0.00	1	22	95.65
PML	0	genome.wustl.edu	37	15	74290386	74290386	+	Silent	SNP	C	C	T			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	15	74290386	74290386	C	T	SNP	PML	ENST00000268058	human	ensembl	74_37	+1	known	silent	c.171	p.C57	0.980	smart_Znf_RING,pfscan_Znf_RING	pfam_DUF3583,pfam_Znf_B-box,smart_Znf_RING,smart_Znf_B-box,pfscan_Znf_B-box,pfscan_Znf_RING	-	no_errors	PML	HGNC	ENSG00000140464	tier1	-	-	67	0	0.00	20	40	66.67	17	0	0.00	7	6	46.15
SATB1	0	genome.wustl.edu	37	3	18457620	18457620	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	18457620	18457620	T	A	SNP	SATB1	ENST00000417717	human	ensembl	74_37	-1	known	missense	c.394	p.I132F	0.999	NULL	pfam_Hmoeo_CUT,pfam_Homeobox_dom,superfamily_Lambda_D-bd_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Hmoeo_CUT	-	no_errors	SATB1	HGNC	ENSG00000182568	tier1	-	-	36	0	0.00	41	9	18.00	67	0	0.00	79	8	9.20
CYP11A1	0	genome.wustl.edu	37	15	74636134	74636134	+	Silent	SNP	A	A	G			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	15	74636134	74636134	A	G	SNP	CYP11A1	ENST00000268053	human	ensembl	74_37	-1	known	silent	c.825	p.S275	0.031	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_mitochondrial,prints_Cyt_P450,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450_B	-	no_errors	CYP11A1	HGNC	ENSG00000140459	tier1	-	-	29	0	0.00	21	4	16.00	69	0	0.00	55	4	6.78
RBM6	0	genome.wustl.edu	37	3	50004794	50004794	+	R	DEL	A	A	-			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	50004794	50004794	A	-	DEL	RBM6	ENST00000488807	human	ensembl	74_37	+1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	RBM6	HGNC	ENSG00000004534	tier1			21	0	0.00	25	3	10.71	47	0	0.00	50	5	9.09
ACADVL	0	genome.wustl.edu	37	17	7123240	7123241	+	R	INS	-	-	GGGCGTGCAGGACGC			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	17	7123240	7123241	-	GGGCGTGCAGGACGC	INS	ACADVL	ENST00000577857	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	ACADVL	HGNC	ENSG00000072778	tier1			5	0	0.00	3	0	0.00	5	0	0.00	3	0	0.00
ANKLE1	0	genome.wustl.edu	37	19	17397486	17397501	+	Frame_Shift_Del	DEL	TGTGTGTGTGTGTGTT	TGTGTGTGTGTGTGTT	-			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	TGTGTGTGTGTGTGTT	TGTGTGTGTGTGTGTT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	19	17397486	17397501	TGTGTGTGTGTGTGTT	-	DEL	ANKLE1	ENST00000598347	human	ensembl	74_37	+1	putative	frame_shift_del	c.1756_1771	p.C590fs	0.820:0.697:0.344:0.098:0.082:0.071:0.072:0.077:0.073:0.072:0.083:0.085:0.079:0.064:0.026:0.004	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_Lactate_DH/Glyco_Ohase_4_C,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ANKLE1	HGNC	ENSG00000160117	tier1			12	0	0.00	5	0	0.00	12	0	0.00	5	0	0.00
XYLB	0	genome.wustl.edu	37	3	38411731	38411732	+	R	INS	-	-	CACCCA			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	3	38411731	38411732	-	CACCCA	INS	XYLB	ENST00000487569	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	XYLB	HGNC	ENSG00000093217	tier1			11	0	0.00	7	0	0.00	11	0	0.00	7	0	0.00
ENSG00000272231	0	genome.wustl.edu	37	12	74293692	74293701	+	R	DEL	ATACACATAC	ATACACATAC	-			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	ATACACATAC	ATACACATAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	12	74293692	74293701	ATACACATAC	-	DEL	ENSG00000272231	ENST00000606199	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.002:0.002:0.002:0.002:0.004:0.007:0.009:0.010:0.011:0.011	-	-	-	no_errors	AC136188.1	Clone_based_ensembl_gene	ENSG00000272231	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ZNF100	0	genome.wustl.edu	37	19	21910048	21910048	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	19	21910048	21910048	G	C	SNP	ZNF100	ENST00000358296	human	ensembl	74_37	-1	known	missense	c.1066	p.Q356E	0.003	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF100	HGNC	ENSG00000197020	tier1	-	-	44	0	0.00	57	25	28.41	3	0	0.00	4	0	0.00
ZNF100	0	genome.wustl.edu	37	19	21910049	21910049	+	Silent	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	19	21910049	21910049	G	A	SNP	ZNF100	ENST00000358296	human	ensembl	74_37	-1	known	silent	c.1065	p.N355	0.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF100	HGNC	ENSG00000197020	tier1	-	-	44	0	0.00	64	25	28.09	3	0	0.00	5	0	0.00
ZNF100	0	genome.wustl.edu	37	19	21910055	21910055	+	Silent	SNP	G	G	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	19	21910055	21910055	G	A	SNP	ZNF100	ENST00000358296	human	ensembl	74_37	-1	known	silent	c.1059	p.A353	0.001	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF100	HGNC	ENSG00000197020	tier1	-	-	44	0	0.00	65	28	30.11	3	0	0.00	5	0	0.00
ZNF839	0	genome.wustl.edu	37	14	102808557	102808558	+	R	INS	-	-	A			TCGA-DX-A23R-01A-11D-A26G-09	TCGA-DX-A23R-10A-01D-A26G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	35c797fd-ca81-4cef-b6c4-7e3776f661b3	daf47fe1-0c16-4711-a274-db2c20165c2c	14	102808557	102808558	-	A	INS	ZNF839	ENST00000420933	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.005:0.008	-	-	-	no_errors	ZNF839	HGNC	ENSG00000022976	tier1			27	0	0.00	15	3	16.67	30	0	0.00	34	2	5.56