Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
VWA8	0	genome.wustl.edu	37	13	42273392	42273392	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	13	42273392	42273392	T	C	SNP	VWA8	ENST00000379310	human	ensembl	74_37	-1	known	missense	c.3379	p.T1127A	0.418	NULL	pfam_ATPase_dyneun-rel_AAA,pfam_VWF_A,superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_VWF_A,pfscan_VWF_A	-	no_errors	VWA8	HGNC	ENSG00000102763	tier1	-	-	21	0	0.00	65	15	18.75	115	0	0.00	115	15	11.54
ISY1-RAB43	0	genome.wustl.edu	37	3	128864635	128864635	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	3	128864635	128864635	C	G	SNP	ISY1-RAB43	ENST00000418265	human	ensembl	74_37	-1	known	missense	c.269	p.R90P	1.000	pfam_Isy1	pfam_Isy1	-	no_errors	ISY1-RAB43	HGNC	ENSG00000261796	tier1	-	-	48	0	0.00	73	13	15.12	121	0	0.00	113	31	21.53
ZNF76	0	genome.wustl.edu	37	6	35255451	35255451	+	Silent	SNP	C	C	T			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	6	35255451	35255451	C	T	SNP	ZNF76	ENST00000373953	human	ensembl	74_37	+1	known	silent	c.261	p.A87	0.896	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF76	HGNC	ENSG00000065029	tier1	-	-	13	0	0.00	11	5	31.25	71	0	0.00	52	28	35.00
CENPE	0	genome.wustl.edu	37	4	104061060	104061060	+	Silent	SNP	G	G	A			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	4	104061060	104061060	G	A	SNP	CENPE	ENST00000265148	human	ensembl	74_37	-1	known	silent	c.6090	p.S2030	0.019	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,superfamily_STAT_TF_coiled-coil,superfamily_Signal_recog_particl_SRP54_hlx,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	CENPE	HGNC	ENSG00000138778	tier1	-	-	79	0	0.00	96	43	30.94	97	0	0.00	66	44	40.00
STARD13	0	genome.wustl.edu	37	13	33684840	33684840	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	13	33684840	33684840	C	T	SNP	STARD13	ENST00000336934	human	ensembl	74_37	-1	known	missense	c.2812	p.D938N	1.000	pfam_START_lipid-bd_dom,smart_START_lipid-bd_dom,pfscan_START_lipid-bd_dom	pfam_START_lipid-bd_dom,pfam_RhoGAP_dom,pfam_SAM_2,superfamily_Rho_GTPase_activation_prot,superfamily_SAM/pointed,smart_RhoGAP_dom,smart_START_lipid-bd_dom,pfscan_START_lipid-bd_dom,pfscan_RhoGAP_dom	-	no_errors	STARD13	HGNC	ENSG00000133121	tier1	-	-	31	0	0.00	45	19	29.69	77	0	0.00	53	18	25.35
OR2T8	0	genome.wustl.edu	37	1	248084815	248084815	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	1	248084815	248084815	T	C	SNP	OR2T8	ENST00000319968	human	ensembl	74_37	+1	known	missense	c.496	p.Y166H	0.124	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2T8	HGNC	ENSG00000177462	tier1	-	-	8	0	0.00	16	8	33.33	15	0	0.00	11	2	15.38
TMEM252	0	genome.wustl.edu	37	9	71155617	71155617	+	Silent	SNP	C	C	A			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	9	71155617	71155617	C	A	SNP	TMEM252	ENST00000377311	human	ensembl	74_37	-1	known	silent	c.114	p.G38	0.000	NULL	NULL	-	no_errors	TMEM252	HGNC	ENSG00000181778	tier1	-	-	23	0	0.00	27	10	27.03	94	0	0.00	73	29	28.16
ESRP1	0	genome.wustl.edu	37	8	95658450	95658450	+	Frame_Shift_Del	DEL	A	A	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	8	95658450	95658450	A	-	DEL	ESRP1	ENST00000433389	human	ensembl	74_37	+1	known	frame_shift_del	c.430	p.K144fs	1.000	superfamily_RNaseH-like_dom	superfamily_RNaseH-like_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	ESRP1	HGNC	ENSG00000104413	tier1			71	0	0.00	53	41	43.62	129	0	0.00	69	19	21.59
PIM1	0	genome.wustl.edu	37	6	37139016	37139025	+	Frame_Shift_Del	DEL	TCCTGGAGAG	TCCTGGAGAG	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	TCCTGGAGAG	TCCTGGAGAG	TCCTGGAGAG	-	TCCTGGAGAG	TCCTGGAGAG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	6	37139016	37139025	TCCTGGAGAG	-	DEL	PIM1	ENST00000373509	human	ensembl	74_37	+1	known	frame_shift_del	c.356_365	p.I119fs	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.944:1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	PIM1	HGNC	ENSG00000137193	tier1			94	0	0.00	67	10	12.99	94	0	0.00	67	10	12.99
VPS45	0	genome.wustl.edu	37	1	150082514	150082514	+	R	DEL	A	A	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	1	150082514	150082514	A	-	DEL	VPS45	ENST00000484306	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.965	-	-	-	no_errors	VPS45	HGNC	ENSG00000136631	tier1			18	0	0.00	31	5	13.89	47	0	0.00	45	6	11.76
MIEF2	0	genome.wustl.edu	37	17	18167708	18167708	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	17	18167708	18167708	A	G	SNP	MIEF2	ENST00000323019	human	ensembl	74_37	+1	known	missense	c.995	p.Q332R	1.000	NULL	NULL	-	no_errors	MIEF2	HGNC	ENSG00000177427	tier1	-	-	19	0	0.00	26	13	33.33	16	0	0.00	9	2	18.18
MYH1	0	genome.wustl.edu	37	17	10404621	10404621	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	17	10404621	10404621	G	T	SNP	MYH1	ENST00000226207	human	ensembl	74_37	-1	known	missense	c.3544	p.L1182M	1.000	pfam_Myosin_tail	pfam_Myosin_tail,pfam_Myosin_head_motor_dom,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,superfamily_tR-bd_arm,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH1	HGNC	ENSG00000109061	tier1	-	-	65	0	0.00	97	55	36.18	14	0	0.00	7	3	30.00
TPM3	0	genome.wustl.edu	37	1	154144674	154144674	+	R	DEL	A	A	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	1	154144674	154144674	A	-	DEL	TPM3	ENST00000469717	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TPM3	HGNC	ENSG00000143549	tier1			22	0	0.00	51	5	8.93	56	0	0.00	60	6	9.09
AZU1	0	genome.wustl.edu	37	19	831755	831755	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	19	831755	831755	C	T	SNP	AZU1	ENST00000233997	human	ensembl	74_37	+1	known	missense	c.634	p.H212Y	0.000	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	AZU1	HGNC	ENSG00000172232	tier1	-	-	38	0	0.00	67	22	24.72	9	0	0.00	6	0	0.00
NEUROG2	0	genome.wustl.edu	37	4	113436358	113436358	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	4	113436358	113436358	G	A	SNP	NEUROG2	ENST00000313341	human	ensembl	74_37	-1	known	missense	c.274	p.R92W	0.709	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	NEUROG2	HGNC	ENSG00000178403	tier1	-	-	33	0	0.00	43	24	35.82	5	0	0.00	2	0	0.00
CABLES1	0	genome.wustl.edu	37	18	20716015	20716023	+	In_Frame_Del	DEL	GGCGCCGGC	GGCGCCGGC	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	GGCGCCGGC	GGCGCCGGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	18	20716015	20716023	GGCGCCGGC	-	DEL	CABLES1	ENST00000256925	human	ensembl	74_37	+1	known	in_frame_del	c.289_297	p.GGA99in_frame_del	0.983:0.981:0.990:0.998:0.999:0.997:0.999:0.999:0.997	pirsf_Cdk5/c-Abl_linker_Cables	pfam_Cyclin_N,superfamily_Cyclin-like,pirsf_Cdk5/c-Abl_linker_Cables	-	no_errors	CABLES1	HGNC	ENSG00000134508	tier1			0	0	0.00	1	0	0.00	0	0	0.00	1	0	0.00
ENSG00000215941	0	genome.wustl.edu	37	3	38948802	38948811	+	R	DEL	TGTGTGTGTG	TGTGTGTGTG	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	TGTGTGTGTG	TGTGTGTGTG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	3	38948802	38948811	TGTGTGTGTG	-	DEL	ENSG00000215941	ENST00000401122	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.000:0.001:0.005:0.007:0.015:0.028:0.021:0.020:0.022:0.022	-	-	-	no_errors	AC116038.1	Clone_based_ensembl_gene	ENSG00000215941	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000215976	0	genome.wustl.edu	37	12	104378945	104378954	+	R	DEL	ACACACACAC	ACACACACAC	-			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	ACACACACAC	ACACACACAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	12	104378945	104378954	ACACACACAC	-	DEL	ENSG00000215976	ENST00000401157	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.022:0.023:0.025:0.026:0.026:0.026:0.026:0.025:0.024:0.023	-	-	-	no_errors	AC078819.1	Clone_based_ensembl_gene	ENSG00000215976	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
LINC00266-1	0	genome.wustl.edu	37	20	62934863	62934864	+	R	INS	-	-	TT			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	20	62934863	62934864	-	TT	INS	LINC00266-1	ENST00000279067	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.448:0.498	-	-	-	no_errors	LINC00266-1	HGNC	ENSG00000149656	tier1			20	0	0.00	37	8	17.78	0	0	0.00	0	0	0.00
ARHGAP29	0	genome.wustl.edu	37	1	94643143	94643144	+	R	INS	-	-	T			TCGA-DX-A3UB-01A-11D-A307-09	TCGA-DX-A3UB-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	66b644e8-b86a-4f11-8e3f-63a9d913f618	db5413dc-7f80-4fbc-a345-6a5d8ed16ad0	1	94643143	94643144	-	T	INS	ARHGAP29	ENST00000482481	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	ARHGAP29	HGNC	ENSG00000137962	tier1			26	0	0.00	41	5	10.87	34	0	0.00	51	2	3.77