Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
PTPN21	0	genome.wustl.edu	37	14	88946616	88946616	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	14	88946616	88946616	C	T	SNP	PTPN21	ENST00000328736	human	ensembl	74_37	-1	known	missense	c.1159	p.G387S	1.000	pirsf_Tyr_Pase_non-rcpt_typ-14/21	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_FERM_central,pfam_FERM_N,pfam_FERM_PH-like_C,superfamily_FERM_central,smart_Band_41_domain,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pirsf_Tyr_Pase_non-rcpt_typ-14/21,pfscan_FERM_domain,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt,prints_Band_41_fam	-	no_errors	PTPN21	HGNC	ENSG00000070778	tier1	-	-	29	0	0.00	27	6	18.18	120	0	0.00	127	26	16.99
PPCS	0	genome.wustl.edu	37	1	42925276	42925276	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	1	42925276	42925276	A	G	SNP	PPCS	ENST00000372561	human	ensembl	74_37	+1	known	missense	c.615	p.I205M	1.000	pfam_D/pantothenate-metab_flavo_C,superfamily_D/pantothenate-metab_flavo_C	pfam_D/pantothenate-metab_flavo_C,superfamily_D/pantothenate-metab_flavo_C	-	no_errors	PPCS	HGNC	ENSG00000127125	tier1	-	-	25	0	0.00	26	38	59.38	139	0	0.00	45	63	58.33
FOLH1	0	genome.wustl.edu	37	11	49207240	49207240	+	Silent	SNP	T	T	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	49207240	49207240	T	G	SNP	FOLH1	ENST00000256999	human	ensembl	74_37	-1	known	silent	c.807	p.T269	1.000	NULL	pfam_TFR-like_dimer_dom,pfam_Protease-assoc_domain,pfam_Peptidase_M28,superfamily_TFR-like_dimer_dom	-	no_errors	FOLH1	HGNC	ENSG00000086205	tier1	-	-	91	0	0.00	72	29	28.71	131	0	0.00	93	25	21.19
ENSG00000227407	0	genome.wustl.edu	37	19	54942232	54942232	+	R	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	54942232	54942232	G	A	SNP	ENSG00000227407	ENST00000457113	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC008746.3	Clone_based_vega_gene	ENSG00000227407	tier1	-	-	61	0	0.00	90	21	18.92	16	0	0.00	15	4	21.05
LOC101927211	0	genome.wustl.edu	37	6	57015419	57015419	+	R	SNP	A	A	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	6	57015419	57015419	A	T	SNP	LOC101927211	ENST00000589263	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-203B9.4	Clone_based_vega_gene	ENSG00000226803	tier1	-	-	30	0	0.00	14	35	71.43	175	0	0.00	36	83	69.75
CLDN8	0	genome.wustl.edu	37	21	31588020	31588020	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	21	31588020	31588020	G	A	SNP	CLDN8	ENST00000286809	human	ensembl	74_37	-1	known	missense	c.224	p.P75L	0.789	pfam_PMP22/EMP/MP20/Claudin	pfam_PMP22/EMP/MP20/Claudin,prints_Claudin,prints_Claudin8,prints_Claudin14	-	no_errors	CLDN8	HGNC	ENSG00000156284	tier1	-	-	62	0	0.00	30	28	48.28	107	0	0.00	25	34	57.63
BCL7B	0	genome.wustl.edu	37	7	72951686	72951686	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	72951686	72951686	G	A	SNP	BCL7B	ENST00000223368	human	ensembl	74_37	-1	known	missense	c.551	p.P184L	0.954	NULL	pfam_BCL7	-	no_errors	BCL7B	HGNC	ENSG00000106635	tier1	-	-	55	0	0.00	32	13	28.89	29	0	0.00	27	19	40.43
MAGEC1	0	genome.wustl.edu	37	X	140996581	140996581	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	X	140996581	140996581	A	G	SNP	MAGEC1	ENST00000285879	human	ensembl	74_37	+1	known	missense	c.3391	p.S1131G	0.009	NULL	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC1	HGNC	ENSG00000155495	tier1	-	-	41	0	0.00	8	48	85.71	75	0	0.00	16	68	80.95
LPHN1	0	genome.wustl.edu	37	19	14288464	14288464	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	14288464	14288464	C	T	SNP	LPHN1	ENST00000340736	human	ensembl	74_37	-1	known	missense	c.163	p.V55I	1.000	pfam_Lectin_gal-bd_dom,pfscan_Lectin_gal-bd_dom	pfam_GPCR_2_latrophilin_rcpt_C,pfam_Olfac-like,pfam_DUF3497,pfam_GPCR_2_secretin-like,pfam_Lectin_gal-bd_dom,pfam_GPS_dom,pfam_GPCR_2_extracellular_dom,smart_Olfac-like,smart_GPCR_2_extracellular_dom,smart_GPS_dom,pfscan_GPS_dom,pfscan_Lectin_gal-bd_dom,pfscan_Olfac-like,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_latrophilin,prints_GPCR_2_secretin-like	-	no_errors	LPHN1	HGNC	ENSG00000072071	tier1	-	-	42	0	0.00	38	8	17.39	52	0	0.00	52	14	21.21
MOGAT2	0	genome.wustl.edu	37	11	75440005	75440005	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	75440005	75440005	T	A	SNP	MOGAT2	ENST00000198801	human	ensembl	74_37	+1	known	missense	c.821	p.I274K	0.099	pfam_DAGAT	pfam_DAGAT	-	no_errors	MOGAT2	HGNC	ENSG00000166391	tier1	-	-	26	0	0.00	29	6	17.14	118	0	0.00	122	14	10.22
OTOG	0	genome.wustl.edu	37	11	17653668	17653668	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	17653668	17653668	C	T	SNP	OTOG	ENST00000399391	human	ensembl	74_37	+1	known	missense	c.7003	p.R2335W	0.999	pfam_Unchr_dom_Cys-rich,smart_Unchr_dom_Cys-rich	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_AbfB,pfam_TIL_dom,superfamily_AbfB,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_EG-like_dom	-	no_errors	OTOG	HGNC	ENSG00000188162	tier1	-	-	57	0	0.00	59	18	23.08	81	0	0.00	76	16	17.39
SIAE	0	genome.wustl.edu	37	11	124543597	124543597	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	124543597	124543597	G	A	SNP	SIAE	ENST00000263593	human	ensembl	74_37	-1	known	missense	c.8	p.A3V	0.000	NULL	pfam_DUF303_acetylest	-	no_errors	SIAE	HGNC	ENSG00000110013	tier1	-	-	232	0	0.00	100	45	31.03	26	0	0.00	21	4	16.00
ILVBL	0	genome.wustl.edu	37	19	15234361	15234361	+	Silent	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	15234361	15234361	G	A	SNP	ILVBL	ENST00000263383	human	ensembl	74_37	-1	known	silent	c.162	p.G54	0.470	pfam_Thiamin_PyroP_enz_TPP-bd_dom	pfam_Thiamin_PyroP_enz_TPP-bd_dom,pfam_TPP_enzyme-bd_C,pfam_Thiamin_PyroP_enz_cen_dom	-	no_errors	ILVBL	HGNC	ENSG00000105135	tier1	-	-	36	0	0.00	21	7	25.00	32	0	0.00	29	9	23.68
GJA8	0	genome.wustl.edu	37	1	147380140	147380140	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	1	147380140	147380140	G	A	SNP	GJA8	ENST00000240986	human	ensembl	74_37	+1	known	missense	c.58	p.V20I	0.995	pfam_Connexin_N	pfam_Connexin_N,pfam_Connexin50,pfam_Connexin_CCC,smart_Connexin_N,prints_Connexin,prints_Connexin50	-	no_errors	GJA8	HGNC	ENSG00000121634	tier1	-	-	35	0	0.00	17	36	67.92	87	0	0.00	26	73	73.74
VSIG10L	0	genome.wustl.edu	37	19	51844468	51844468	+	Silent	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	51844468	51844468	C	T	SNP	VSIG10L	ENST00000335624	human	ensembl	74_37	-1	novel	silent	c.834	p.T278	0.015	smart_Ig_sub	smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	VSIG10L	HGNC	ENSG00000186806	tier1	-	-	72	0	0.00	82	18	18.00	55	0	0.00	61	19	23.75
CHR7	0	genome.wustl.edu	37	15	32460274	32460274	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	15	32460274	32460274	C	T	SNP	CHR7	ENST00000454250	human	ensembl	74_37	+1	known	missense	c.1211	p.A404V	0.031	pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,prints_Nicotinic_acetylcholine_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	CHR7	HGNC	ENSG00000175344	tier1	-	-	108	0	0.00	103	19	15.57	6	0	0.00	10	2	16.67
FAT1	0	genome.wustl.edu	37	4	187539627	187539627	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	4	187539627	187539627	C	A	SNP	FAT1	ENST00000441802	human	ensembl	74_37	-1	known	nonsense	c.8113	p.E2705*	1.000	superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,smart_EG-like_dom,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,prints_Cadherin,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin	-	no_errors	FAT1	HGNC	ENSG00000083857	tier1	-	-	31	0	0.00	7	21	75.00	156	0	0.00	27	59	68.60
SCN8A	0	genome.wustl.edu	37	12	52159701	52159701	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	12	52159701	52159701	C	T	SNP	SCN8A	ENST00000354534	human	ensembl	74_37	+1	known	nonsense	c.2791	p.R931*	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,pfam_IQ_motif_EF-hand-BS,smart_IQ_motif_EF-hand-BS,prints_Na_channel_a8su,prints_Na_channel_asu,prints_PKD_2,pfscan_IQ_motif_EF-hand-BS	-	no_errors	SCN8A	HGNC	ENSG00000196876	tier1	-	-	69	0	0.00	53	23	30.26	109	0	0.00	69	16	18.82
ITGB7	0	genome.wustl.edu	37	12	53585695	53585695	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	12	53585695	53585695	C	T	SNP	ITGB7	ENST00000267082	human	ensembl	74_37	-1	known	missense	c.2264	p.R755H	0.996	pirsf_Integrin_bsu,pfam_Integrin_bsu_cyt_dom,prints_Integrin_bsu	pirsf_Integrin_bsu,pfam_Integrin_bsu_N,pfam_Integrin_bsu_cyt_dom,pfam_EGF_extracell,superfamily_Plexin-like_fold,superfamily_Integrin_bsu_tail,smart_Plexin-like_fold,smart_Integrin_bsu_N,prints_Integrin_bsu	-	no_errors	ITGB7	HGNC	ENSG00000139626	tier1	-	-	91	0	0.00	68	17	20.00	46	0	0.00	32	16	32.65
SLC7A3	0	genome.wustl.edu	37	X	70147136	70147136	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	X	70147136	70147136	G	A	SNP	SLC7A3	ENST00000298085	human	ensembl	74_37	-1	known	missense	c.1282	p.L428F	1.000	pfam_AA-permease/SLC12A_dom,pirsf_AA/rel_permease1,tigrfam_Cat_AA_permease	pfam_AA-permease/SLC12A_dom,pirsf_AA/rel_permease1,tigrfam_Cat_AA_permease	-	no_errors	SLC7A3	HGNC	ENSG00000165349	tier1	-	-	25	0	0.00	21	20	48.78	46	0	0.00	39	27	40.91
KIAA0355	0	genome.wustl.edu	37	19	34838875	34838875	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	34838875	34838875	A	T	SNP	KIAA0355	ENST00000299505	human	ensembl	74_37	+1	known	missense	c.2615	p.N872I	1.000	NULL	NULL	-	no_errors	KIAA0355	HGNC	ENSG00000166398	tier1	-	-	39	0	0.00	30	11	26.19	42	0	0.00	42	14	25.00
RGS3	0	genome.wustl.edu	37	9	116359104	116359104	+	Silent	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	9	116359104	116359104	G	A	SNP	RGS3	ENST00000350696	human	ensembl	74_37	+1	known	silent	c.3468	p.T1156	0.345	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam	pfam_RGS_dom,pfam_C2_dom,pfam_PDZ,superfamily_Regulat_G_prot_signal_superfam,superfamily_C2_dom,superfamily_PDZ,smart_C2_dom,smart_PDZ,smart_Regulat_G_prot_signal_superfam,pfscan_C2_dom,pfscan_PDZ,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS3	HGNC	ENSG00000138835	tier1	-	-	72	0	0.00	77	16	17.20	43	0	0.00	44	25	36.23
AQP12B	0	genome.wustl.edu	37	2	241622006	241622006	+	Silent	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	2	241622006	241622006	G	A	SNP	AQP12B	ENST00000407834	human	ensembl	74_37	-1	known	silent	c.249	p.H83	0.972	pfam_MIP,superfamily_Aquaporin-like,pirsf_Aquaporin_11/12,prints_MIP	pfam_MIP,superfamily_Aquaporin-like,pirsf_Aquaporin_11/12,prints_Aquaporin_12,prints_MIP	-	no_errors	AQP12B	HGNC	ENSG00000185176	tier1	-	-	127	0	0.00	88	25	22.12	52	1	1.89	44	6	11.54
HAPLN1	0	genome.wustl.edu	37	5	82940427	82940427	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	5	82940427	82940427	G	A	SNP	HAPLN1	ENST00000274341	human	ensembl	74_37	-1	known	missense	c.530	p.A177V	1.000	pfam_Link,superfamily_C-type_lectin_fold,smart_Link,pfscan_Link,prints_Link	pfam_Link,pfam_Ig_V-set,superfamily_C-type_lectin_fold,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Link,pfscan_Link,pfscan_Ig-like_dom,prints_Link	-	no_errors	HAPLN1	HGNC	ENSG00000145681	tier1	-	-	41	0	0.00	38	16	29.63	61	0	0.00	46	16	25.81
ITPR2	0	genome.wustl.edu	37	12	26592165	26592165	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	12	26592165	26592165	C	A	SNP	ITPR2	ENST00000381340	human	ensembl	74_37	-1	known	missense	c.6538	p.V2180L	0.996	NULL	pfam_Ca-rel_channel,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ARM-type_fold,smart_MIR_motif,prints_InsP3_rcpt-bd,pfscan_MIR_motif	-	no_errors	ITPR2	HGNC	ENSG00000123104	tier1	-	-	57	0	0.00	26	19	42.22	109	0	0.00	31	27	46.55
AASDHPPT	0	genome.wustl.edu	37	11	105967630	105967630	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	105967630	105967630	C	T	SNP	AASDHPPT	ENST00000278618	human	ensembl	74_37	+1	known	missense	c.926	p.S309L	1.000	NULL	pfam_4-PPantetheinyl_Trfase_SF,superfamily_4-PPantetheinyl_Trfase_SF	-	no_errors	AASDHPPT	HGNC	ENSG00000149313	tier1	-	-	25	0	0.00	11	7	38.89	129	0	0.00	66	38	36.54
SHANK1	0	genome.wustl.edu	37	19	51201120	51201120	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	51201120	51201120	C	T	SNP	SHANK1	ENST00000391814	human	ensembl	74_37	-1	known	missense	c.1841	p.R614H	0.109	superfamily_SH3_domain	pfam_Ankyrin_rpt,pfam_SAM_type1,pfam_SH3_2,pfam_SAM_2,pfam_PDZ,pfam_SH3_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_PDZ,superfamily_SH3_domain,superfamily_SAM/pointed,smart_Ankyrin_rpt,smart_SH3_domain,smart_PDZ,smart_SAM,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_PDZ,pfscan_SAM,pfscan_SH3_domain	-	no_errors	SHANK1	HGNC	ENSG00000161681	tier1	-	-	78	0	0.00	78	25	24.27	90	0	0.00	85	31	26.72
TOX2	0	genome.wustl.edu	37	20	42635240	42635240	+	Silent	SNP	A	A	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	20	42635240	42635240	A	T	SNP	TOX2	ENST00000341197	human	ensembl	74_37	+1	known	silent	c.219	p.T73	0.963	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	TOX2	HGNC	ENSG00000124191	tier1	-	-	58	0	0.00	31	18	36.73	101	1	0.97	41	21	33.87
OR2V2	0	genome.wustl.edu	37	5	180582017	180582017	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	5	180582017	180582017	C	A	SNP	OR2V2	ENST00000328275	human	ensembl	74_37	+1	known	missense	c.75	p.D25E	0.000	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2V2	HGNC	ENSG00000182613	tier1	-	-	76	0	0.00	62	26	29.55	88	0	0.00	59	30	33.71
ZNF467	0	genome.wustl.edu	37	7	149462898	149462898	+	Silent	SNP	C	C	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	149462898	149462898	C	A	SNP	ZNF467	ENST00000302017	human	ensembl	74_37	-1	known	silent	c.693	p.L231	1.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF467	HGNC	ENSG00000181444	tier1	-	-	34	0	0.00	39	10	20.41	15	0	0.00	12	5	29.41
STAB2	0	genome.wustl.edu	37	12	103981330	103981330	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	12	103981330	103981330	G	T	SNP	STAB2	ENST00000388887	human	ensembl	74_37	+1	known	missense	c.76	p.G26W	0.000	NULL	pfam_FAS1_domain,pfam_Link,superfamily_C-type_lectin_fold,superfamily_FAS1_domain,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF_laminin,smart_EGF-like_Ca-bd_dom,smart_FAS1_domain,smart_Link,pfscan_EG-like_dom,pfscan_FAS1_domain,pfscan_Link	-	no_errors	STAB2	HGNC	ENSG00000136011	tier1	-	-	44	0	0.00	41	9	18.00	129	0	0.00	88	15	14.56
LILRA1	0	genome.wustl.edu	37	19	55107308	55107308	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	55107308	55107308	G	A	SNP	LILRA1	ENST00000251372	human	ensembl	74_37	+1	known	missense	c.866	p.R289H	0.000	smart_Ig_sub,smart_Ig_sub2,pirsf_A1B_glyco/leuk_Ig-like_rcpt	smart_Ig_sub,smart_Ig_sub2,pirsf_A1B_glyco/leuk_Ig-like_rcpt,pfscan_Ig-like_dom	-	no_errors	LILRA1	HGNC	ENSG00000104974	tier1	-	-	185	0	0.00	148	41	21.58	8	0	0.00	13	2	13.33
HPSE2	0	genome.wustl.edu	37	10	100503735	100503735	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	100503735	100503735	C	T	SNP	HPSE2	ENST00000370552	human	ensembl	74_37	-1	known	missense	c.689	p.R230H	1.000	pfam_Glyco_hydro_79,superfamily_Glycoside_hydrolase_SF	pfam_Glyco_hydro_79,superfamily_Glycoside_hydrolase_SF	-	no_errors	HPSE2	HGNC	ENSG00000172987	tier1	-	-	56	0	0.00	28	12	30.00	149	0	0.00	63	39	38.24
MYO18B	0	genome.wustl.edu	37	22	26247469	26247469	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	22	26247469	26247469	C	T	SNP	MYO18B	ENST00000335473	human	ensembl	74_37	+1	known	missense	c.3808	p.R1270C	1.000	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,superfamily_tR-bd_arm,superfamily_Ribosomal_zn-bd,smart_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO18B	HGNC	ENSG00000133454	tier1	-	-	53	0	0.00	72	30	29.41	39	0	0.00	57	14	19.72
SSPO	0	genome.wustl.edu	37	7	149480380	149480380	+	R	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	149480380	149480380	C	T	SNP	SSPO	ENST00000262089	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	SSPO	HGNC	ENSG00000197558	tier1	-	-	30	0	0.00	57	9	13.64	31	0	0.00	26	7	21.21
GPR50	0	genome.wustl.edu	37	X	150345294	150345294	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	X	150345294	150345294	C	T	SNP	GPR50	ENST00000218316	human	ensembl	74_37	+1	known	missense	c.101	p.A34V	0.649	prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Mel_rcpt_1X,prints_GPCR_Rhodpsn,prints_Melatonin_rcpt,prints_NPY_rcpt	-	no_errors	GPR50	HGNC	ENSG00000102195	tier1	-	-	71	0	0.00	62	35	36.08	44	0	0.00	51	18	26.09
DTHD1	0	genome.wustl.edu	37	4	36295187	36295187	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	4	36295187	36295187	T	G	SNP	DTHD1	ENST00000456874	human	ensembl	74_37	+1	known	missense	c.883	p.F295V	1.000	NULL	pfam_Death_domain,superfamily_DEATH-like_dom,pfscan_Death_domain	-	no_errors	DTHD1	HGNC	ENSG00000197057	tier1	-	-	67	0	0.00	70	18	20.45	142	0	0.00	97	28	22.40
RSAD1	0	genome.wustl.edu	37	17	48562112	48562112	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	17	48562112	48562112	C	T	SNP	RSAD1	ENST00000258955	human	ensembl	74_37	+1	known	missense	c.1219	p.R407W	1.000	pfam_HemN_C_dom	pfam_HemN_C_dom,pfam_rSAM,smart_Elp3/MiaB/NifB,tigrfam_Coprogen_oxidase_HemN-rel	-	no_errors	RSAD1	HGNC	ENSG00000136444	tier1	-	-	79	0	0.00	51	25	32.89	105	0	0.00	81	26	24.30
CERKL	0	genome.wustl.edu	37	2	182403828	182403828	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	2	182403828	182403828	A	G	SNP	CERKL	ENST00000339098	human	ensembl	74_37	-1	known	missense	c.1607	p.V536A	1.000	NULL	pfam_Diacylglycerol_kinase_cat_dom	-	no_errors	CERKL	HGNC	ENSG00000188452	tier1	-	-	161	0	0.00	28	88	75.86	79	0	0.00	19	55	74.32
ZNF665	0	genome.wustl.edu	37	19	53668216	53668216	+	Silent	SNP	A	A	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	53668216	53668216	A	G	SNP	ZNF665	ENST00000396424	human	ensembl	74_37	-1	known	silent	c.1527	p.T509	0.405	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF665	HGNC	ENSG00000197497	tier1	-	-	55	0	0.00	90	23	20.35	27	0	0.00	37	12	24.49
TRPV5	0	genome.wustl.edu	37	7	142627168	142627168	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	142627168	142627168	A	G	SNP	TRPV5	ENST00000265310	human	ensembl	74_37	-1	known	missense	c.334	p.C112R	0.779	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom,prints_TRPV5/TRPV6,tigrfam_TRP_channel	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_TRPV5/TRPV6,prints_TRPV5,prints_Ankyrin_rpt,tigrfam_TRP_channel	-	no_errors	TRPV5	HGNC	ENSG00000127412	tier1	-	-	32	0	0.00	19	9	32.14	110	0	0.00	48	25	34.25
CNTP2	0	genome.wustl.edu	37	7	148080943	148080943	+	Silent	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	148080943	148080943	C	T	SNP	CNTP2	ENST00000361727	human	ensembl	74_37	+1	known	silent	c.3678	p.S1226	0.004	NULL	pfam_Laminin_G,pfam_Coagulation_fac_5/8-C_type_dom,pfam_EG-like_dom,superfamily_Galactose-bd-like,superfamily_ConA-like_lec_gl_sf,superfamily_Fibrinogen_a/b/g_C_dom,smart_Coagulation_fac_5/8-C_type_dom,smart_Laminin_G,smart_EG-like_dom,smart_Neurexin-like,pfscan_EG-like_dom,pfscan_Coagulation_fac_5/8-C_type_dom,pfscan_Laminin_G	-	no_errors	CNTP2	HGNC	ENSG00000174469	tier1	-	-	42	0	0.00	66	15	18.52	36	0	0.00	35	6	14.63
PCDHA6	0	genome.wustl.edu	37	5	140208762	140208762	+	Silent	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	5	140208762	140208762	C	T	SNP	PCDHA6	ENST00000529310	human	ensembl	74_37	+1	known	silent	c.1086	p.D362	0.935	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA6	HGNC	ENSG00000081842	tier1	-	-	70	0	0.00	40	12	23.08	24	0	0.00	13	8	38.10
C10orf54	0	genome.wustl.edu	37	10	73521633	73521633	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	73521633	73521633	C	T	SNP	C10orf54	ENST00000394957	human	ensembl	74_37	-1	known	missense	c.233	p.G78D	0.018	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	C10orf54	HGNC	ENSG00000107738	tier1	-	-	24	0	0.00	17	13	43.33	54	0	0.00	22	9	29.03
KIR3DX1	0	genome.wustl.edu	37	19	55048149	55048149	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	55048149	55048149	A	C	SNP	KIR3DX1	ENST00000335056	human	ensembl	74_37	+1	known	missense	c.716	p.K239T	0.063	smart_Ig_sub,pfscan_Ig-like_dom	pfam_Immunoglobulin,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	KIR3DX1	HGNC	ENSG00000104970	tier1	-	-	47	0	0.00	30	10	25.00	95	0	0.00	68	25	26.60
HPSE2	0	genome.wustl.edu	37	10	100242511	100242511	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	100242511	100242511	G	T	SNP	HPSE2	ENST00000370552	human	ensembl	74_37	-1	known	missense	c.1495	p.L499I	1.000	NULL	pfam_Glyco_hydro_79,superfamily_Glycoside_hydrolase_SF	-	no_errors	HPSE2	HGNC	ENSG00000172987	tier1	-	-	45	0	0.00	34	11	24.44	123	1	0.81	50	29	36.71
ANK3	0	genome.wustl.edu	37	10	61834026	61834026	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	61834026	61834026	G	T	SNP	ANK3	ENST00000280772	human	ensembl	74_37	-1	known	missense	c.6613	p.P2205T	0.998	NULL	pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt	-	no_errors	ANK3	HGNC	ENSG00000151150	tier1	-	-	34	0	0.00	16	7	30.43	160	1	0.62	53	39	42.39
LRP2	0	genome.wustl.edu	37	2	170062573	170062573	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	2	170062573	170062573	C	T	SNP	LRP2	ENST00000263816	human	ensembl	74_37	-1	known	missense	c.7516	p.V2506I	0.815	smart_LDLR_classB_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,superfamily_TIL_dom,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP2	HGNC	ENSG00000081479	tier1	rs199918722	-	18	0	0.00	2	16	88.89	148	0	0.00	21	77	78.57
MMRN2	0	genome.wustl.edu	37	10	88717176	88717176	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	88717176	88717176	C	T	SNP	MMRN2	ENST00000372027	human	ensembl	74_37	-1	known	nonsense	c.123	p.W41*	0.002	NULL	pfam_C1q,pfam_EMI_domain,superfamily_Tumour_necrosis_fac-like_dom,superfamily_tR-bd_arm,smart_C1q,prints_C1q,pfscan_C1q,pfscan_EMI_domain	-	no_errors	MMRN2	HGNC	ENSG00000173269	tier1	-	-	68	0	0.00	13	15	53.57	76	0	0.00	28	17	37.78
TP53I11	0	genome.wustl.edu	37	11	44925357	44925357	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	44925357	44925357	G	A	SNP	TP53I11	ENST00000354556	human	ensembl	74_37	-1	known	missense	c.419	p.A140V	0.001	NULL	NULL	-	no_errors	TP53I11	HGNC	ENSG00000175274	tier1	-	-	60	0	0.00	64	10	13.51	182	0	0.00	134	38	22.09
GALNT18	0	genome.wustl.edu	37	11	11454275	11454275	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	11454275	11454275	A	T	SNP	GALNT18	ENST00000227756	human	ensembl	74_37	-1	known	missense	c.488	p.V163D	1.000	pfam_Glyco_trans_2	pfam_Glyco_trans_2,pfam_Ricin_B_lectin,superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin	-	no_errors	GALNT18	HGNC	ENSG00000110328	tier1	-	-	39	0	0.00	32	5	13.51	65	0	0.00	83	12	12.63
PMCHL1	0	genome.wustl.edu	37	5	22142560	22142560	+	R	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	5	22142560	22142560	C	T	SNP	PMCHL1	ENST00000418902	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.975	-	-	-	no_errors	PMCHL1	HGNC	ENSG00000168967	tier1	-	-	86	0	0.00	110	19	14.73	135	0	0.00	121	33	21.43
GUCY2F	0	genome.wustl.edu	37	X	108708524	108708524	+	Silent	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	X	108708524	108708524	G	T	SNP	GUCY2F	ENST00000218006	human	ensembl	74_37	-1	known	silent	c.879	p.T293	0.978	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_A/G_cyclase,pfam_ANF_lig-bd_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Haem_no_assoc-bd,superfamily_Peripla_BP_I,superfamily_A/G_cyclase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_A/G_cyclase,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_A/G_cyclase	-	no_errors	GUCY2F	HGNC	ENSG00000101890	tier1	-	-	36	0	0.00	42	25	37.31	82	0	0.00	59	36	37.89
TFDP1	0	genome.wustl.edu	37	13	114294576	114294576	+	Silent	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	13	114294576	114294576	C	T	SNP	TFDP1	ENST00000375370	human	ensembl	74_37	+1	known	silent	c.1227	p.D409	0.006	NULL	pfam_Transc_factor_DP_C,pfam_E2F_TDP,pirsf_Transcrpt_fac_DP	-	no_errors	TFDP1	HGNC	ENSG00000198176	tier1	-	-	65	0	0.00	69	53	43.44	30	0	0.00	32	12	27.27
MROH7-TTC4	0	genome.wustl.edu	37	1	55151962	55151962	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	1	55151962	55151962	T	G	SNP	MROH7-TTC4	ENST00000414150	human	ensembl	74_37	+1	known	missense	c.2552	p.V851G	0.997	superfamily_ARM-type_fold	superfamily_ARM-type_fold	-	no_errors	MROH7-TTC4	HGNC	ENSG00000271723	tier1	-	-	31	0	0.00	16	27	62.79	54	0	0.00	28	20	41.67
HCAR2	0	genome.wustl.edu	37	12	123187043	123187043	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	12	123187043	123187043	G	A	SNP	HCAR2	ENST00000328880	human	ensembl	74_37	-1	known	missense	c.788	p.T263M	0.001	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	-	no_errors	HCAR2	HGNC	ENSG00000182782	tier1	-	-	59	0	0.00	47	10	17.54	74	0	0.00	53	13	19.40
KLK15	0	genome.wustl.edu	37	19	51330315	51330315	+	Silent	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	51330315	51330315	C	T	SNP	KLK15	ENST00000598239	human	ensembl	74_37	-1	known	silent	c.300	p.A100	0.000	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	KLK15	HGNC	ENSG00000174562	tier1	-	-	45	0	0.00	37	11	22.92	20	0	0.00	27	9	25.00
SEZ6L	0	genome.wustl.edu	37	22	26688611	26688611	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	22	26688611	26688611	G	A	SNP	SEZ6L	ENST00000248933	human	ensembl	74_37	+1	known	missense	c.334	p.A112T	0.000	NULL	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	SEZ6L	HGNC	ENSG00000100095	tier1	-	-	128	0	0.00	224	28	11.02	45	0	0.00	77	13	14.44
LHX5	0	genome.wustl.edu	37	12	113906052	113906052	+	Silent	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	12	113906052	113906052	G	T	SNP	LHX5	ENST00000261731	human	ensembl	74_37	-1	known	silent	c.555	p.T185	1.000	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_Znf_LIM,pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Znf_LIM,smart_Homeobox_dom,pfscan_Znf_LIM,pfscan_Homeobox_dom	-	no_errors	LHX5	HGNC	ENSG00000089116	tier1	-	-	41	0	0.00	16	7	30.43	16	0	0.00	15	6	28.57
PKHD1	0	genome.wustl.edu	37	6	51747956	51747956	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	6	51747956	51747956	C	T	SNP	PKHD1	ENST00000371117	human	ensembl	74_37	-1	known	missense	c.7285	p.V2429I	1.000	superfamily_Pectin_lyase_fold/virulence,smart_PbH1	pfam_IPT,pfam_G8_domain,superfamily_Ig_E-set,superfamily_Pectin_lyase_fold/virulence,smart_IPT,smart_PbH1	-	no_errors	PKHD1	HGNC	ENSG00000170927	tier1	rs148284341	-	65	0	0.00	74	17	18.68	139	0	0.00	172	26	13.13
MYO5B	0	genome.wustl.edu	37	18	47431168	47431168	+	Silent	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	18	47431168	47431168	C	T	SNP	MYO5B	ENST00000285039	human	ensembl	74_37	-1	known	silent	c.2445	p.A815	0.001	pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS	pfam_Myosin_head_motor_dom,pfam_Dil_domain,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_Dilute,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO5B	HGNC	ENSG00000167306	tier1	-	-	110	0	0.00	67	18	21.18	62	0	0.00	42	17	28.81
ARAP2	0	genome.wustl.edu	37	4	36212335	36212335	+	Silent	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	4	36212335	36212335	G	A	SNP	ARAP2	ENST00000303965	human	ensembl	74_37	-1	known	silent	c.1164	p.S388	0.810	NULL	pfam_RhoGAP_dom,pfam_Pleckstrin_homology,pfam_ArfGAP,pfam_SAM_type1,pfam_SAM_2,pfam_Ras-assoc,superfamily_Rho_GTPase_activation_prot,superfamily_SAM/pointed,smart_SAM,smart_Pleckstrin_homology,smart_ArfGAP,smart_RhoGAP_dom,pfscan_Pleckstrin_homology,pfscan_Ras-assoc,pfscan_SAM,pfscan_ArfGAP,pfscan_RhoGAP_dom,prints_ArfGAP	-	no_errors	ARAP2	HGNC	ENSG00000047365	tier1	-	-	21	0	0.00	13	12	48.00	132	0	0.00	93	59	38.56
CLEC3A	0	genome.wustl.edu	37	16	78064763	78064763	+	R	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	16	78064763	78064763	G	T	SNP	CLEC3A	ENST00000565808	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.578	-	-	-	no_errors	CLEC3A	HGNC	ENSG00000166509	tier1	-	-	47	0	0.00	30	19	38.78	125	1	0.79	48	18	27.27
MYBPC3	0	genome.wustl.edu	37	11	47372888	47372888	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	47372888	47372888	G	A	SNP	MYBPC3	ENST00000399249	human	ensembl	74_37	-1	known	missense	c.194	p.T65M	0.997	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2	pfam_Ig_I-set,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	MYBPC3	HGNC	ENSG00000134571	tier1	-	-	39	0	0.00	26	4	13.33	52	0	0.00	55	10	15.38
ING2	0	genome.wustl.edu	37	4	184431445	184431445	+	Silent	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	4	184431445	184431445	G	A	SNP	ING2	ENST00000302327	human	ensembl	74_37	+1	known	silent	c.183	p.K61	1.000	NULL	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,pfscan_Znf_PHD-finger	-	no_errors	ING2	HGNC	ENSG00000168556	tier1	-	-	36	0	0.00	19	22	52.38	64	0	0.00	26	10	27.78
KCNG4	0	genome.wustl.edu	37	16	84270517	84270517	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	16	84270517	84270517	C	T	SNP	KCNG4	ENST00000308251	human	ensembl	74_37	-1	known	missense	c.575	p.R192H	0.000	NULL	pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,prints_K_chnl,prints_K_chnl_volt-dep_Kv6,prints_K_chnl_volt-dep_Kv9,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv3	-	no_errors	KCNG4	HGNC	ENSG00000168418	tier1	-	-	89	0	0.00	23	18	41.86	23	0	0.00	11	3	21.43
SF1	0	genome.wustl.edu	37	11	64532898	64532898	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	64532898	64532898	C	T	SNP	SF1	ENST00000334944	human	ensembl	74_37	-1	known	missense	c.1880	p.R627H	1.000	NULL	pfam_KH_dom_type_1,pfam_Znf_CCHC,superfamily_Znf_CCHC,smart_KH_dom,smart_Znf_CCHC,pfscan_Znf_CCHC,pfscan_KH_dom_type_1	-	no_errors	SF1	HGNC	ENSG00000168066	tier1	-	-	55	0	0.00	45	13	22.41	137	0	0.00	118	35	22.88
VRTN	0	genome.wustl.edu	37	14	74823735	74823735	+	Silent	SNP	C	C	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	14	74823735	74823735	C	A	SNP	VRTN	ENST00000256362	human	ensembl	74_37	+1	known	silent	c.249	p.G83	0.967	NULL	pfam_Transposase_8	-	no_errors	VRTN	HGNC	ENSG00000133980	tier1	-	-	15	0	0.00	16	9	34.62	9	0	0.00	16	2	11.11
OR4C5	0	genome.wustl.edu	37	11	48387926	48387926	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	11	48387926	48387926	G	A	SNP	OR4C5	ENST00000319813	human	ensembl	74_37	-1	known	missense	c.92	p.T31M	0.963	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4C5	HGNC	ENSG00000176540	tier1	-	-	68	0	0.00	57	14	19.72	136	1	0.73	77	34	30.63
COL22A1	0	genome.wustl.edu	37	8	139606332	139606332	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	8	139606332	139606332	C	T	SNP	COL22A1	ENST00000303045	human	ensembl	74_37	-1	known	missense	c.4543	p.G1515S	1.000	pfam_Collagen	pfam_Collagen,pfam_VWF_A,superfamily_ConA-like_lec_gl_sf,smart_VWF_A,smart_Laminin_G,pfscan_VWF_A	-	no_errors	COL22A1	HGNC	ENSG00000169436	tier1	-	-	90	0	0.00	39	17	30.36	17	0	0.00	7	7	50.00
KCNH2	0	genome.wustl.edu	37	7	150642533	150642533	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	150642533	150642533	G	A	SNP	KCNH2	ENST00000262186	human	ensembl	74_37	-1	known	nonsense	c.3400	p.R1134*	0.996	NULL	pfam_Ion_trans_dom,pfam_2pore_dom_K_chnl_dom,pfam_cNMP-bd_dom,pfam_PAS_fold,pfam_PAS_fold_3,superfamily_cNMP-bd-like,superfamily_PAS,smart_PAC,smart_cNMP-bd_dom,prints_K_chnl_volt-dep_EAG/ELK/ERG,prints_K_chnl_volt-dep_ERG,pfscan_cNMP-bd_dom,pfscan_PAS,pfscan_PAS-assoc_C,tigrfam_PAS	-	no_errors	KCNH2	HGNC	ENSG00000055118	tier1	-	-	40	0	0.00	32	32	50.00	13	0	0.00	8	13	61.90
KIR3DL2	0	genome.wustl.edu	37	19	55363537	55363537	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	55363537	55363537	G	A	SNP	KIR3DL2	ENST00000326321	human	ensembl	74_37	+1	known	missense	c.155	p.R52H	0.000	pfam_Immunoglobulin,smart_Ig_sub	pfam_Immunoglobulin,smart_Ig_sub	-	no_errors	KIR3DL2	HGNC	ENSG00000240403	tier1	-	-	31	0	0.00	20	12	37.50	12	0	0.00	6	3	33.33
KLF2	0	genome.wustl.edu	37	19	16437824	16437824	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	16437824	16437824	C	T	SNP	KLF2	ENST00000592003	human	ensembl	74_37	+1	putative	missense	c.233	p.T78I	1.000	NULL	NULL	-	no_errors	KLF2	HGNC	ENSG00000127528	tier1	-	-	55	0	0.00	74	16	17.78	6	0	0.00	7	3	30.00
MATK	0	genome.wustl.edu	37	19	3778349	3778349	+	Silent	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	3778349	3778349	G	A	SNP	MATK	ENST00000395045	human	ensembl	74_37	-1	known	silent	c.1359	p.P453	0.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH2,pfam_SH3_domain,superfamily_Kinase-like_dom,superfamily_SH3_domain,smart_SH3_domain,smart_SH2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_SH2,pfscan_SH3_domain,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH2	-	no_errors	MATK	HGNC	ENSG00000007264	tier1	-	-	79	0	0.00	11	63	85.14	17	0	0.00	5	24	82.76
FTMT	0	genome.wustl.edu	37	5	121187750	121187750	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	5	121187750	121187750	G	A	SNP	FTMT	ENST00000321339	human	ensembl	74_37	+1	known	missense	c.92	p.R31H	0.371	NULL	pfam_Ferritin_DPS_dom,superfamily_Ferritin-like_SF,pfscan_Ferritin-like_diiron	-	no_errors	FTMT	HGNC	ENSG00000181867	tier1	-	-	24	0	0.00	14	6	30.00	5	0	0.00	2	1	33.33
KCNMA1	0	genome.wustl.edu	37	10	79397225	79397225	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	79397225	79397225	G	T	SNP	KCNMA1	ENST00000406533	human	ensembl	74_37	-1	known	missense	c.176	p.S59Y	1.000	NULL	pfam_K_chnl_Ca-activ_BK_asu,pfam_Ion_trans_dom,pfam_2pore_dom_K_chnl_dom,pfam_RCK_N,prints_K_chnl_Ca-activ_BK_asu,prints_K_chnl	-	no_errors	KCNMA1	HGNC	ENSG00000156113	tier1	-	-	37	0	0.00	47	15	24.19	7	0	0.00	6	1	14.29
ANKRD30BP2	0	genome.wustl.edu	37	21	14410709	14410709	+	R	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	21	14410709	14410709	C	T	SNP	ANKRD30BP2	ENST00000507941	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ANKRD30BP2	HGNC	ENSG00000224309	tier1	-	-	127	0	0.00	93	18	16.22	2	0	0.00	1	0	0.00
ENSG00000201913	0	genome.wustl.edu	37	7	99928403	99928403	+	R	SNP	T	T	C			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	99928403	99928403	T	C	SNP	ENSG00000201913	ENST00000365043	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.023	-	-	-	no_errors	Y_R	RFAM	ENSG00000201913	tier1	-	-	35	0	0.00	37	5	11.90	0	0	0.00	0	0	0.00
FAM86B3P	0	genome.wustl.edu	37	8	8092059	8092059	+	R	SNP	A	A	G			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	8	8092059	8092059	A	G	SNP	FAM86B3P	ENST00000522601	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.354	-	-	-	no_errors	FAM86B3P	HGNC	ENSG00000173295	tier1	-	-	216	0	0.00	199	39	16.32	0	0	0.00	0	0	0.00
KCNMA1	0	genome.wustl.edu	37	10	79397243	79397243	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	10	79397243	79397243	G	A	SNP	KCNMA1	ENST00000406533	human	ensembl	74_37	-1	known	missense	c.158	p.S53F	0.999	NULL	pfam_K_chnl_Ca-activ_BK_asu,pfam_Ion_trans_dom,pfam_2pore_dom_K_chnl_dom,pfam_RCK_N,prints_K_chnl_Ca-activ_BK_asu,prints_K_chnl	-	no_errors	KCNMA1	HGNC	ENSG00000156113	tier1	-	-	27	0	0.00	42	13	23.64	4	0	0.00	5	0	0.00
LOC101927345	0	genome.wustl.edu	37	1	143378850	143378850	+	R	SNP	G	G	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	1	143378850	143378850	G	T	SNP	LOC101927345	ENST00000423394	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-435B5.5	Clone_based_vega_gene	ENSG00000238261	tier1	-	-	160	0	0.00	196	24	10.91	0	0	0.00	1	0	0.00
MEGF9	0	genome.wustl.edu	37	9	123476543	123476548	+	In_Frame_Del	DEL	CGGCGG	CGGCGG	-			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	CGGCGG	CGGCGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	9	123476543	123476548	CGGCGG	-	DEL	MEGF9	ENST00000426959	human	ensembl	74_37	-1	known	in_frame_del	c.70_65	p.AA22in_frame_del	0.255:0.243:0.247:0.263:0.993:0.998	NULL	pfam_EGF_laminin,smart_EGF_laminin,smart_EG-like_dom,pfscan_EGF_laminin	-	no_errors	MEGF9	HGNC	ENSG00000106780	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
NXNL2	0	genome.wustl.edu	37	9	91150536	91150536	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	9	91150536	91150536	G	A	SNP	NXNL2	ENST00000375854	human	ensembl	74_37	+1	known	missense	c.187	p.A63T	0.997	superfamily_Thioredoxin-like_fold	superfamily_Thioredoxin-like_fold	-	no_errors	NXNL2	HGNC	ENSG00000130045	tier1	-	-	11	0	0.00	8	4	33.33	4	0	0.00	0	2	100.00
CENPO	0	genome.wustl.edu	37	2	25016757	25016757	+	R	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	2	25016757	25016757	C	T	SNP	CENPO	ENST00000473476	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.001	-	-	-	no_errors	CENPO	HGNC	ENSG00000138092	tier1	-	-	67	0	0.00	29	5	14.71	117	0	0.00	54	2	3.57
MYO1G	0	genome.wustl.edu	37	7	45005706	45005706	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	7	45005706	45005706	C	T	SNP	MYO1G	ENST00000258787	human	ensembl	74_37	-1	known	missense	c.2123	p.R708H	0.001	superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom	-	no_errors	MYO1G	HGNC	ENSG00000136286	tier1	-	-	32	0	0.00	9	7	43.75	32	0	0.00	35	2	5.41
HCN2	0	genome.wustl.edu	37	19	603785	603785	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	19	603785	603785	G	A	SNP	HCN2	ENST00000251287	human	ensembl	74_37	+1	known	missense	c.874	p.V292M	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_N,pfam_cNMP-bd_dom,pfam_Ion_trans_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom,prints_K_chnl_volt-dep_EAG/ELK/ERG	-	no_errors	HCN2	HGNC	ENSG00000099822	tier1	-	-	71	0	0.00	56	12	17.65	32	0	0.00	36	2	5.26
USP32P1	0	genome.wustl.edu	37	17	16706243	16706243	+	R	SNP	G	G	A			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	17	16706243	16706243	G	A	SNP	USP32P1	ENST00000341745	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.061	-	-	-	no_errors	USP32P1	HGNC	ENSG00000188933	tier1	-	-	67	0	0.00	94	20	17.54	44	0	0.00	43	2	4.44
CP	0	genome.wustl.edu	37	3	148924108	148924108	+	Frame_Shift_Del	DEL	A	A	-			TCGA-DX-A6YR-01A-33D-A351-09	TCGA-DX-A6YR-10B-01D-A351-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0851f971-c95c-4c39-8390-f62598885c5a	f97fc91e-8830-4217-9c02-02531bdffc59	3	148924108	148924108	A	-	DEL	CP	ENST00000264613	human	ensembl	74_37	-1	known	frame_shift_del	c.1055	p.F352fs	1.000	pfam_Cu-oxidase_2,pfam_Cu-oxidase,superfamily_Cupredoxin	pfam_Cu-oxidase_2,pfam_Cu-oxidase_3,pfam_Cu-oxidase,superfamily_Cupredoxin	-	no_errors	CP	HGNC	ENSG00000047457	tier1			28	0	0.00	22	3	12.00	142	0	0.00	85	2	2.30