Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SHBG	0	genome.wustl.edu	37	17	7534625	7534625	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	17	7534625	7534625	C	T	SNP	SHBG	ENST00000570353	human	ensembl	74_37	+1	known	missense	c.409	p.H137Y	0.001	NULL	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf	-	no_errors	SHBG	HGNC	ENSG00000129214	tier1	-	-	29	0	0.00	15	24	61.54	60	0	0.00	22	16	42.11
SLC25A32	0	genome.wustl.edu	37	8	104417074	104417074	+	Silent	SNP	C	C	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	8	104417074	104417074	C	T	SNP	SLC25A32	ENST00000297578	human	ensembl	74_37	-1	known	silent	c.321	p.K107	1.000	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_uncoupling	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_uncoupling	-	no_errors	SLC25A32	HGNC	ENSG00000164933	tier1	-	-	39	0	0.00	14	5	26.32	93	0	0.00	37	35	48.61
RB1	0	genome.wustl.edu	37	13	48939108	48939108	+	Splice_Site	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	13	48939108	48939108	G	A	SNP	RB1	ENST00000267163	human	ensembl	74_37	+1	known	splice_site	c.939+1	e9+1	1.000	-	-	-	no_errors	RB1	HGNC	ENSG00000139687	tier1	-	-	62	0	0.00	62	27	30.34	60	0	0.00	42	11	20.75
PXDNL	0	genome.wustl.edu	37	8	52284449	52284449	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	8	52284449	52284449	C	T	SNP	PXDNL	ENST00000356297	human	ensembl	74_37	-1	known	nonsense	c.3885	p.W1295*	1.000	superfamily_Haem_peroxidase,pfscan_Haem_peroxidase_animal	pfam_Haem_peroxidase_animal,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_VWF_C,pfam_Leu-rich_rpt,superfamily_Haem_peroxidase,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,smart_VWF_C,prints_Haem_peroxidase_animal_subgr,pfscan_VWF_C,pfscan_Haem_peroxidase_animal,pfscan_Ig-like_dom	-	no_errors	PXDNL	HGNC	ENSG00000147485	tier1	-	-	19	0	0.00	22	6	21.43	58	0	0.00	42	14	25.00
KIF1B	0	genome.wustl.edu	37	1	10318638	10318638	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	1	10318638	10318638	G	T	SNP	KIF1B	ENST00000263934	human	ensembl	74_37	+1	known	missense	c.271	p.V91F	1.000	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	pfam_Kinesin_motor_dom,pfam_Kinesin-like,pfam_Pleckstrin_homology,pfam_KIF1B,pfam_FHA_dom,superfamily_P-loop_NTPase,superfamily_SMAD_FHA_domain,smart_Kinesin_motor_dom,smart_FHA_dom,smart_Pleckstrin_homology,pfscan_FHA_dom,pfscan_Pleckstrin_homology,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF1B	HGNC	ENSG00000054523	tier1	-	-	74	0	0.00	75	21	21.88	113	0	0.00	90	33	26.83
IQGAP3	0	genome.wustl.edu	37	1	156510676	156510676	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	1	156510676	156510676	G	A	SNP	IQGAP3	ENST00000361170	human	ensembl	74_37	-1	known	missense	c.2563	p.R855C	0.643	NULL	pfam_RasGAP,pfam_RasGAP_C,pfam_IQ_motif_EF-hand-BS,pfam_CH-domain,superfamily_Rho_GTPase_activation_prot,superfamily_CH-domain,superfamily_P-loop_NTPase,superfamily_WW_dom,smart_CH-domain,smart_IQ_motif_EF-hand-BS,smart_RasGAP,pfscan_CH-domain,pfscan_IQ_motif_EF-hand-BS,pfscan_RasGAP	-	no_errors	IQGAP3	HGNC	ENSG00000183856	tier1	-	-	20	0	0.00	30	12	28.57	57	0	0.00	49	17	25.76
CCDC181	0	genome.wustl.edu	37	1	169391311	169391311	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	1	169391311	169391311	C	A	SNP	CCDC181	ENST00000367806	human	ensembl	74_37	-1	known	missense	c.358	p.D120Y	1.000	NULL	NULL	-	no_errors	CCDC181	HGNC	ENSG00000117477	tier1	-	-	21	0	0.00	13	9	40.91	29	0	0.00	23	15	39.47
KLC2	0	genome.wustl.edu	37	11	66032513	66032513	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	11	66032513	66032513	G	A	SNP	KLC2	ENST00000316924	human	ensembl	74_37	+1	known	nonsense	c.1236	p.W412*	1.000	NULL	pfam_Rabaptin_Rab5-bd_dom,pfam_TPR_1,smart_TPR_repeat,prints_Kinesin_light,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	KLC2	HGNC	ENSG00000174996	tier1	-	-	17	0	0.00	17	14	45.16	60	0	0.00	40	18	30.51
PARP8	0	genome.wustl.edu	37	5	50130827	50130827	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	5	50130827	50130827	G	A	SNP	PARP8	ENST00000281631	human	ensembl	74_37	+1	known	missense	c.2440	p.V814I	1.000	pfscan_Poly(ADP-ribose)pol_cat_dom	pfam_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_cat_dom	-	no_errors	PARP8	HGNC	ENSG00000151883	tier1	-	-	59	0	0.00	32	14	30.43	107	0	0.00	65	46	41.44
TOP1MT	0	genome.wustl.edu	37	8	144397980	144397980	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	8	144397980	144397980	C	G	SNP	TOP1MT	ENST00000329245	human	ensembl	74_37	-1	known	missense	c.1470	p.K490N	1.000	pfam_TopoI_cat_euk,superfamily_D_brk_join_enz,smart_TopoI_euk	pfam_TopoI_D-bd_euk,pfam_TopoI_cat_euk,superfamily_TopoI_D-bd_euk,superfamily_D_brk_join_enz,smart_TopoI_euk,prints_TopoI	-	no_errors	TOP1MT	HGNC	ENSG00000184428	tier1	-	-	60	0	0.00	60	16	21.05	31	0	0.00	26	4	13.33
BCL7A	0	genome.wustl.edu	37	12	122492735	122492735	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	12	122492735	122492735	A	C	SNP	BCL7A	ENST00000538010	human	ensembl	74_37	+1	known	missense	c.464	p.Q155P	1.000	NULL	pfam_BCL7	-	no_errors	BCL7A	HGNC	ENSG00000110987	tier1	-	-	41	0	0.00	30	7	18.92	52	0	0.00	45	5	10.00
FAM135B	0	genome.wustl.edu	37	8	139164696	139164696	+	Silent	SNP	C	C	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	8	139164696	139164696	C	T	SNP	FAM135B	ENST00000395297	human	ensembl	74_37	-1	known	silent	c.2022	p.G674	0.136	NULL	pfam_DUF676_lipase-like,pfam_DUF3657,pfam_PGAP1-like	-	no_errors	FAM135B	HGNC	ENSG00000147724	tier1	-	-	30	0	0.00	25	11	30.56	90	0	0.00	83	23	21.70
PCSK5	0	genome.wustl.edu	37	9	78710909	78710909	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	9	78710909	78710909	T	C	SNP	PCSK5	ENST00000545128	human	ensembl	74_37	+1	known	missense	c.998	p.I333T	1.000	pfam_Peptidase_S8/S53_dom,superfamily_Peptidase_S8/S53_dom	pfam_Peptidase_S8/S53_dom,pfam_PrprotnconvertsP,superfamily_Peptidase_S8/S53_dom,superfamily_Galactose-bd-like,superfamily_Growth_fac_rcpt_N_dom,superfamily_Prot_inh_propept,smart_Furin_repeat,smart_EG-like_dom,prints_Peptidase_S8_subtilisin-rel	-	no_errors	PCSK5	HGNC	ENSG00000099139	tier1	-	-	46	0	0.00	29	7	19.44	142	0	0.00	142	23	13.94
LAPTM5	0	genome.wustl.edu	37	1	31214657	31214657	+	R	SNP	G	G	C			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	1	31214657	31214657	G	C	SNP	LAPTM5	ENST00000476492	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	LAPTM5	HGNC	ENSG00000162511	tier1	-	-	25	0	0.00	13	4	23.53	79	0	0.00	61	20	24.69
OCRL	0	genome.wustl.edu	37	X	128723702	128723702	+	R	SNP	A	A	G			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	X	128723702	128723702	A	G	SNP	OCRL	ENST00000463271	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	OCRL	HGNC	ENSG00000122126	tier1	-	-	41	0	0.00	8	6	42.86	133	0	0.00	57	47	45.19
GPR37	0	genome.wustl.edu	37	7	124404110	124404110	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	7	124404110	124404110	G	C	SNP	GPR37	ENST00000303921	human	ensembl	74_37	-1	known	missense	c.921	p.D307E	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPR37_orph,prints_GPCR_Rhodpsn	-	no_errors	GPR37	HGNC	ENSG00000170775	tier1	-	-	33	0	0.00	31	18	36.73	86	0	0.00	56	24	30.00
ANO7	0	genome.wustl.edu	37	2	242162614	242162614	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	2	242162614	242162614	C	T	SNP	ANO7	ENST00000274979	human	ensembl	74_37	+1	known	missense	c.2497	p.R833W	0.985	pfam_Anoctamin	pfam_Anoctamin	-	no_errors	ANO7	HGNC	ENSG00000146205	tier1	-	-	55	0	0.00	58	19	24.68	105	0	0.00	103	42	28.77
IGFBP7	0	genome.wustl.edu	37	4	57907080	57907080	+	Silent	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	4	57907080	57907080	G	A	SNP	IGFBP7	ENST00000295666	human	ensembl	74_37	-1	known	silent	c.495	p.P165	0.989	pfam_Ig_I-set,pirsf_IGFBP_rP_mac25,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Kazal_dom,pfam_IGFBP-like,smart_IGFBP-like,smart_Kazal_dom,smart_Ig_sub,pirsf_IGFBP_rP_mac25,pfscan_Ig-like_dom	-	no_errors	IGFBP7	HGNC	ENSG00000163453	tier1	-	-	24	0	0.00	31	18	36.73	111	0	0.00	99	28	21.88
USP45	0	genome.wustl.edu	37	6	99894289	99894289	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	6	99894289	99894289	T	A	SNP	USP45	ENST00000327681	human	ensembl	74_37	-1	known	missense	c.1359	p.E453D	0.934	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Peptidase_C19/C67,pfam_Znf_UBP,superfamily_Znf_FYVE_PHD,pfscan_Znf_UBP,pfscan_Peptidase_C19/C67	-	no_errors	USP45	HGNC	ENSG00000123552	tier1	-	-	47	0	0.00	31	10	24.39	85	0	0.00	50	21	29.58
DCLK3	0	genome.wustl.edu	37	3	36759571	36759571	+	Silent	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	3	36759571	36759571	G	A	SNP	DCLK3	ENST00000416516	human	ensembl	74_37	-1	known	silent	c.1683	p.D561	0.748	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	DCLK3	HGNC	ENSG00000163673	tier1	-	-	58	0	0.00	43	29	40.28	98	0	0.00	67	28	29.47
RYR2	0	genome.wustl.edu	37	1	237780697	237780697	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	1	237780697	237780697	C	G	SNP	RYR2	ENST00000360064	human	ensembl	74_37	+1	known	missense	c.5821	p.R1941G	1.000	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_hand_dom,pfscan_MIR_motif	-	no_errors	RYR2	HGNC	ENSG00000198626	tier1	-	-	36	0	0.00	29	6	17.14	122	0	0.00	75	10	11.76
DMD	0	genome.wustl.edu	37	X	32519917	32519917	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	X	32519917	32519917	C	A	SNP	DMD	ENST00000357033	human	ensembl	74_37	-1	known	missense	c.2335	p.D779Y	1.000	pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin,pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	DMD	HGNC	ENSG00000198947	tier1	-	-	35	0	0.00	4	8	66.67	58	0	0.00	25	17	40.48
ATN1	0	genome.wustl.edu	37	12	7045892	7045900	+	In_Frame_Del	DEL	CAGCAGCAG	CAGCAGCAG	-			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	CAGCAGCAG	CAGCAGCAG	CAGCAGCAG	-	CAGCAGCAG	CAGCAGCAG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	12	7045892	7045900	CAGCAGCAG	-	DEL	ATN1	ENST00000356654	human	ensembl	74_37	+1	known	in_frame_del	c.1462_1470	p.QQQ491in_frame_del	0.834:0.709:0.730:0.772:0.719:0.700:0.962:0.955:0.948	pfam_Atrophin-like	pfam_Atrophin-like,prints_Atrophin-1	-	no_errors	ATN1	HGNC	ENSG00000111676	tier1			18	0	0.00	14	5	26.32	18	0	0.00	14	5	26.32
NR0B1	0	genome.wustl.edu	37	X	30326646	30326646	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	X	30326646	30326646	G	A	SNP	NR0B1	ENST00000378970	human	ensembl	74_37	-1	known	missense	c.835	p.P279S	1.000	superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	-	no_errors	NR0B1	HGNC	ENSG00000169297	tier1	rs183613764	GMAF=0	48	0	0.00	34	18	34.62	15	0	0.00	7	4	36.36
WDR24	0	genome.wustl.edu	37	16	736871	736871	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	16	736871	736871	G	A	SNP	WDR24	ENST00000248142	human	ensembl	74_37	-1	known	missense	c.1595	p.T532M	0.358	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDR24	HGNC	ENSG00000127580	tier1	-	-	33	0	0.00	47	15	24.19	12	0	0.00	8	5	38.46
ZDHHC1	0	genome.wustl.edu	37	16	67432540	67432540	+	Silent	SNP	G	G	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	16	67432540	67432540	G	A	SNP	ZDHHC1	ENST00000348579	human	ensembl	74_37	-1	known	silent	c.750	p.L250	0.998	NULL	pfam_Znf_DHHC_palmitoyltrfase,pfscan_Znf_DHHC_palmitoyltrfase	-	no_errors	ZDHHC1	HGNC	ENSG00000159714	tier1	-	-	30	0	0.00	17	11	39.29	16	0	0.00	8	5	38.46
GJD2	0	genome.wustl.edu	37	15	35045372	35045372	+	Silent	SNP	A	A	G			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	15	35045372	35045372	A	G	SNP	GJD2	ENST00000290374	human	ensembl	74_37	-1	known	silent	c.273	p.L91	1.000	pfam_Connexin_N,prints_Connexin	pfam_Connexin_N,pfam_Connexin_CCC,smart_Connexin_N,prints_Connexin,prints_Connexin36	-	no_errors	GJD2	HGNC	ENSG00000159248	tier1	-	-	42	0	0.00	27	5	15.62	85	0	0.00	65	4	5.80
MAGIX	0	genome.wustl.edu	37	X	49022648	49022648	+	Silent	SNP	G	G	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	X	49022648	49022648	G	T	SNP	MAGIX	ENST00000412696	human	ensembl	74_37	+1	known	silent	c.915	p.V305	0.996	NULL	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	MAGIX	HGNC	ENSG00000017621	tier1	-	-	38	0	0.00	46	4	8.00	13	0	0.00	9	0	0.00
ENSG00000221684	0	genome.wustl.edu	37	X	70979242	70979259	+	R	DEL	GCGCGCGCGTGCACATGT	GCGCGCGCGTGCACATGT	-			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	GCGCGCGCGTGCACATGT	GCGCGCGCGTGCACATGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	X	70979242	70979259	GCGCGCGCGTGCACATGT	-	DEL	ENSG00000221684	ENST00000408757	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.033:0.033:0.033:0.033:0.033:0.032:0.030:0.029:0.027:0.024:0.022:0.019:0.015:0.012:0.007:0.002:0.000:0.000	-	-	-	no_errors	BX276092.1	Clone_based_ensembl_gene	ENSG00000221684	tier1			1	0	0.00	1	0	0.00	1	0	0.00	1	0	0.00
ENSG00000256616	0	genome.wustl.edu	37	18	12076541	12076542	+	R	INS	-	-	CGCCGCCGCCGC			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	18	12076541	12076542	-	CGCCGCCGCCGC	INS	ENSG00000256616	ENST00000591780	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.834:0.844	-	-	-	no_errors	RP11-815J4.6	Clone_based_vega_gene	ENSG00000256616	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
PCDHA3	0	genome.wustl.edu	37	5	140182991	140182991	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	5	140182991	140182991	C	T	SNP	PCDHA3	ENST00000522353	human	ensembl	74_37	+1	known	missense	c.2209	p.P737S	0.005	NULL	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA3	HGNC	ENSG00000255408	tier1	-	-	41	0	0.00	35	4	10.26	4	0	0.00	1	0	0.00
PDXK	0	genome.wustl.edu	37	21	45157549	45157590	+	R	DEL	GGGCCAGGAGCCTGCCGACGGACACCAGCGAGGGGCCAGGCC	GGGCCAGGAGCCTGCCGACGGACACCAGCGAGGGGCCAGGCC	-			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	GGGCCAGGAGCCTGCCGACGGACACCAGCGAGGGGCCAGGCC	GGGCCAGGAGCCTGCCGACGGACACCAGCGAGGGGCCAGGCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	21	45157549	45157590	GGGCCAGGAGCCTGCCGACGGACACCAGCGAGGGGCCAGGCC	-	DEL	PDXK	ENST00000476313	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002:0.002:0.001:0.000:0.000:0.000:0.001:0.000:0.000:0.000:0.001:0.001:0.001:0.000:0.000:0.000:0.000:0.001:0.000:0.001:0.002:0.001:0.001:0.001:0.000:0.000:0.000:0.000:0.000:0.001:0.002:0.003:0.003:0.004:0.003:0.003:0.001:0.000:0.001:0.000:0.000:0.000	-	-	-	no_errors	PDXK	HGNC	ENSG00000160209	tier1			1	0	0.00	4	0	0.00	1	0	0.00	4	0	0.00
TMEM191A	0	genome.wustl.edu	37	22	21055368	21055369	+	R	INS	-	-	A			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	22	21055368	21055369	-	A	INS	TMEM191A	ENST00000359859	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.006:0.005	-	-	-	no_errors	TMEM191A	HGNC	ENSG00000226287	tier1			13	0	0.00	7	2	22.22	0	0	0.00	0	0	0.00
MUC4	0	genome.wustl.edu	37	3	195512406	195512406	+	Silent	SNP	G	G	T			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	3	195512406	195512406	G	T	SNP	MUC4	ENST00000463781	human	ensembl	74_37	-1	known	silent	c.6045	p.T2015	0.008	NULL	pfam_Nidogen_extracell_dom,pfam_AMOP,pfam_VWF_type-D,smart_Nidogen_extracell_dom,smart_AMOP,smart_VWF_type-D,smart_EG-like_dom,pfscan_AMOP,pfscan_EG-like_dom	-	no_errors	MUC4	HGNC	ENSG00000145113	tier1	-	-	123	0	0.00	119	27	18.49	49	0	0.00	21	2	8.70
NR1D2	0	genome.wustl.edu	37	3	24009400	24009426	+	In_Frame_Del	DEL	ATGGGAGCAGGGGATCTGCTAAACTCT	ATGGGAGCAGGGGATCTGCTAAACTCT	-			TCGA-DX-A8BO-01A-11D-A417-09	TCGA-DX-A8BO-10B-01D-A41A-09	ATGGGAGCAGGGGATCTGCTAAACTCT	ATGGGAGCAGGGGATCTGCTAAACTCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7451845d-6c6f-44fe-adb1-38fc5e9a3792	97a5fef7-598e-4438-b671-e66791a6de2d	3	24009400	24009426	ATGGGAGCAGGGGATCTGCTAAACTCT	-	DEL	NR1D2	ENST00000312521	human	ensembl	74_37	+1	known	in_frame_del	c.1429_1455	p.GAGDLLNSM478in_frame_del	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.919:1.000:1.000:0.089:1.000:1.000:0.973:1.000:1.000:0.998:1.000:1.000:0.963:1.000:1.000:1.000:1.000:1.000:0.903	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core	pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	NR1D2	HGNC	ENSG00000174738	tier1			135	0	0.00	104	2	1.89	135	0	0.00	104	2	1.89