Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ANKK1	0	genome.wustl.edu	37	11	113270544	113270544	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	113270544	113270544	A	T	SNP	ANKK1	ENST00000303941	human	ensembl	74_37	+1	known	missense	c.1853	p.N618I	0.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Ankyrin_rpt,prints_Ankyrin_rpt,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom	-	no_errors	ANKK1	HGNC	ENSG00000170209	tier1	-	-	24	0	0.00	20	7	25.93	43	0	0.00	28	17	37.78
PCLO	0	genome.wustl.edu	37	7	82579403	82579403	+	Missense_Mutation	SNP	T	T	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	7	82579403	82579403	T	G	SNP	PCLO	ENST00000333891	human	ensembl	74_37	-1	known	missense	c.10501	p.M3501L	0.406	NULL	pfam_Znf_piccolo,pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_PDZ,superfamily_Znf_FYVE_PHD,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ	-	no_errors	PCLO	HGNC	ENSG00000186472	tier1	-	-	57	0	0.00	49	18	26.87	91	0	0.00	73	10	12.05
DH10	0	genome.wustl.edu	37	12	124341717	124341717	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	12	124341717	124341717	C	T	SNP	DH10	ENST00000409039	human	ensembl	74_37	+1	known	missense	c.6199	p.R2067C	1.000	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_PyrdxlP-dep_Trfase,smart_AAA+_ATPase	-	no_errors	DH10	HGNC	ENSG00000197653	tier1	-	-	124	0	0.00	130	24	15.58	79	0	0.00	70	15	17.65
ZBTB44	0	genome.wustl.edu	37	11	130103271	130103271	+	Missense_Mutation	SNP	A	A	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	130103271	130103271	A	G	SNP	ZBTB44	ENST00000357899	human	ensembl	74_37	-1	known	missense	c.1693	p.S565P	0.178	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB44	HGNC	ENSG00000196323	tier1	-	-	114	0	0.00	81	15	15.62	56	0	0.00	30	9	23.08
DCLK3	0	genome.wustl.edu	37	3	36779370	36779370	+	Missense_Mutation	SNP	T	T	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	3	36779370	36779370	T	C	SNP	DCLK3	ENST00000416516	human	ensembl	74_37	-1	known	missense	c.781	p.K261E	0.193	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	DCLK3	HGNC	ENSG00000163673	tier1	-	-	47	0	0.00	38	6	13.64	78	0	0.00	77	24	23.76
LOC253044	0	genome.wustl.edu	37	15	77934287	77934287	+	R	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	15	77934287	77934287	G	A	SNP	LOC253044	ENST00000558691	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	RP11-307C19.3	Clone_based_vega_gene	ENSG00000259666	tier1	-	-	43	0	0.00	36	7	16.28	93	1	1.06	70	8	10.26
LOC101927060	0	genome.wustl.edu	37	17	45095748	45095748	+	R	SNP	C	C	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	17	45095748	45095748	C	A	SNP	LOC101927060	ENST00000575173	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-156P1.3	Clone_based_vega_gene	ENSG00000262879	tier1	-	-	208	0	0.00	156	21	11.86	59	0	0.00	51	6	10.34
CECR2	0	genome.wustl.edu	37	22	18020346	18020346	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	22	18020346	18020346	C	T	SNP	CECR2	ENST00000400573	human	ensembl	74_37	+1	novel	missense	c.1675	p.R559C	0.152	NULL	pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain	-	no_errors	CECR2	HGNC	ENSG00000099954	tier1	-	-	38	0	0.00	21	13	38.24	59	0	0.00	35	18	33.96
FANCB	0	genome.wustl.edu	37	X	14882869	14882869	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	X	14882869	14882869	G	A	SNP	FANCB	ENST00000324138	human	ensembl	74_37	-1	known	missense	c.764	p.S255F	1.000	NULL	NULL	-	no_errors	FANCB	HGNC	ENSG00000181544	tier1	-	-	40	0	0.00	37	7	15.56	79	0	0.00	63	13	17.11
PPARGC1B	0	genome.wustl.edu	37	5	149216579	149216579	+	Nonsense_Mutation	SNP	C	C	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	5	149216579	149216579	C	G	SNP	PPARGC1B	ENST00000309241	human	ensembl	74_37	+1	known	nonsense	c.2561	p.S854*	0.998	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	PPARGC1B	HGNC	ENSG00000155846	tier1	-	-	43	0	0.00	25	9	26.47	24	0	0.00	11	9	45.00
PADI3	0	genome.wustl.edu	37	1	17588628	17588628	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	1	17588628	17588628	G	T	SNP	PADI3	ENST00000375460	human	ensembl	74_37	+1	known	missense	c.274	p.V92F	1.000	pfam_PAD_N,superfamily_Cupredoxin,pirsf_Protein-arginine_deiminase_sub	pfam_PAD_C,pfam_Prot_Arg_deaminase_cen_dom,pfam_PAD_N,superfamily_Prot_Arg_deaminase_cen_dom,superfamily_Cupredoxin,pirsf_Protein-arginine_deiminase_sub	-	no_errors	PADI3	HGNC	ENSG00000142619	tier1	-	-	41	0	0.00	32	12	27.27	75	0	0.00	41	20	32.79
TSSK1B	0	genome.wustl.edu	37	5	112769636	112769636	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	5	112769636	112769636	C	T	SNP	TSSK1B	ENST00000390666	human	ensembl	74_37	-1	known	missense	c.901	p.E301K	0.590	superfamily_Kinase-like_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	TSSK1B	HGNC	ENSG00000212122	tier1	-	-	33	0	0.00	25	6	19.35	76	0	0.00	33	12	26.67
KCNK9	0	genome.wustl.edu	37	8	140631178	140631178	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	8	140631178	140631178	G	C	SNP	KCNK9	ENST00000303015	human	ensembl	74_37	-1	known	missense	c.448	p.R150G	1.000	pirsf_2pore_dom_K_chnl_TASK	pfam_2pore_dom_K_chnl_dom,pirsf_2pore_dom_K_chnl_TASK,prints_2pore_dom_K_chnl_TASK,prints_KCNK9,prints_2pore_dom_K_chnl	-	no_errors	KCNK9	HGNC	ENSG00000169427	tier1	-	-	55	0	0.00	29	6	17.14	33	0	0.00	29	6	17.14
LRRC30	0	genome.wustl.edu	37	18	7231229	7231229	+	Silent	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	18	7231229	7231229	C	T	SNP	LRRC30	ENST00000383467	human	ensembl	74_37	+1	known	silent	c.93	p.D31	0.033	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC30	HGNC	ENSG00000206422	tier1	-	-	33	0	0.00	13	5	27.78	86	0	0.00	53	21	28.38
MPPED1	0	genome.wustl.edu	37	22	43831030	43831030	+	Silent	SNP	A	A	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	22	43831030	43831030	A	C	SNP	MPPED1	ENST00000538182	human	ensembl	74_37	+1	known	silent	c.400	p.R134	0.921	NULL	pfam_PEstase_dom	-	no_errors	MPPED1	HGNC	ENSG00000186732	tier1	-	-	83	0	0.00	31	51	62.20	55	0	0.00	43	72	62.61
GLIPR1L2	0	genome.wustl.edu	37	12	75824639	75824639	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	12	75824639	75824639	C	T	SNP	GLIPR1L2	ENST00000550916	human	ensembl	74_37	+1	known	missense	c.733	p.R245W	1.000	NULL	pfam_CAP_domain,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1,prints_Allrgn_V5/Tpx1	-	no_errors	GLIPR1L2	HGNC	ENSG00000180481	tier1	-	-	140	0	0.00	87	27	23.68	83	0	0.00	83	26	23.85
ACO1	0	genome.wustl.edu	37	9	32418329	32418329	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	9	32418329	32418329	G	A	SNP	ACO1	ENST00000309951	human	ensembl	74_37	+1	known	missense	c.478	p.G160S	1.000	pfam_Acoase/IPM_deHydtase_lsu_aba,superfamily_Acoase/IPM_deHydtase_lsu_aba,tigrfam_Aconitase/Fe_reg_prot_2	pfam_Acoase/IPM_deHydtase_lsu_aba,pfam_AconitaseA/IPMdHydase_ssu_swvl,superfamily_Acoase/IPM_deHydtase_lsu_aba,superfamily_Aconitase/3IPM_dehydase_swvl,prints_Acoase/IPM_deHydtase_lsu_aba,tigrfam_Aconitase/Fe_reg_prot_2	-	no_errors	ACO1	HGNC	ENSG00000122729	tier1	-	-	143	0	0.00	78	20	20.20	125	0	0.00	96	22	18.64
PRKG1	0	genome.wustl.edu	37	10	52834636	52834636	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	10	52834636	52834636	C	A	SNP	PRKG1	ENST00000373980	human	ensembl	74_37	+1	known	missense	c.286	p.L96M	1.000	pirsf_cGMP-dependent_protein_kinase,superfamily_cNMP-bd-like	pirsf_cGMP-dependent_protein_kinase,pfam_Prot_kinase_dom,pfam_cNMP-bd_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,prints_cGMP_dep_kinase,prints_cAMP/cGMP_kin,pfscan_cNMP-bd_dom,pfscan_Prot_kinase_dom	-	no_errors	PRKG1	HGNC	ENSG00000185532	tier1	-	-	107	0	0.00	53	23	30.26	38	0	0.00	21	13	38.24
C2orf44	0	genome.wustl.edu	37	2	24262326	24262326	+	Silent	SNP	C	C	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	2	24262326	24262326	C	G	SNP	C2orf44	ENST00000295148	human	ensembl	74_37	-1	known	silent	c.39	p.L13	0.998	NULL	NULL	-	no_errors	C2orf44	HGNC	ENSG00000163026	tier1	-	-	34	0	0.00	18	8	30.77	113	0	0.00	64	22	25.58
EEA1	0	genome.wustl.edu	37	12	93196420	93196420	+	Missense_Mutation	SNP	T	T	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	12	93196420	93196420	T	G	SNP	EEA1	ENST00000322349	human	ensembl	74_37	-1	known	missense	c.2430	p.K810N	0.000	NULL	pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pfscan_Znf_FYVE-rel,pfscan_Znf_C2H2	-	no_errors	EEA1	HGNC	ENSG00000102189	tier1	-	-	25	0	0.00	22	9	29.03	28	0	0.00	67	21	23.86
FOCAD	0	genome.wustl.edu	37	9	20789525	20789525	+	Missense_Mutation	SNP	A	A	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	9	20789525	20789525	A	C	SNP	FOCAD	ENST00000338382	human	ensembl	74_37	+1	known	missense	c.1373	p.H458P	0.999	NULL	pfam_DUF3028,pfam_DUF3730,superfamily_ARM-type_fold	-	no_errors	FOCAD	HGNC	ENSG00000188352	tier1	-	-	48	0	0.00	30	12	28.57	110	0	0.00	47	21	30.88
SEZ6L2	0	genome.wustl.edu	37	16	29906619	29906619	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	16	29906619	29906619	G	A	SNP	SEZ6L2	ENST00000308713	human	ensembl	74_37	-1	known	missense	c.814	p.R272W	0.746	superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_Sushi_SCR_CCP,pfam_CUB_dom,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	SEZ6L2	HGNC	ENSG00000174938	tier1	-	-	76	0	0.00	52	13	20.00	56	0	0.00	46	14	23.33
CPAMD8	0	genome.wustl.edu	37	19	17088328	17088328	+	Silent	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	19	17088328	17088328	A	T	SNP	CPAMD8	ENST00000443236	human	ensembl	74_37	-1	known	silent	c.1749	p.A583	0.155	pfam_A2M_N_2	pfam_A2M_comp,pfam_A2M_N_2,pfam_Methyltransf_FA,pfam_Macroglobln_a2,pfam_A-macroglobulin_rcpt-bd,pfam_A2M_N,pfam_MacrogloblnA2_thiol-ester-bond,pfam_Kazal_dom,superfamily_Terpenoid_cyclase/PrenylTrfase,superfamily_A-macroglobulin_rcpt-bd,smart_Kazal_dom	-	no_errors	CPAMD8	HGNC	ENSG00000160111	tier1	-	-	40	0	0.00	15	5	25.00	16	0	0.00	14	9	39.13
MYOCD	0	genome.wustl.edu	37	17	12666808	12666808	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	17	12666808	12666808	A	T	SNP	MYOCD	ENST00000425538	human	ensembl	74_37	+1	known	missense	c.2808	p.E936D	0.998	NULL	pfam_RPEL_repeat,pfam_SAP_dom,smart_RPEL_repeat,smart_SAP_dom,pfscan_RPEL_repeat,pfscan_SAP_dom	-	no_errors	MYOCD	HGNC	ENSG00000141052	tier1	-	-	43	0	0.00	34	5	12.82	63	0	0.00	60	8	11.76
PTPRT	0	genome.wustl.edu	37	20	40735528	40735528	+	Silent	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	20	40735528	40735528	G	A	SNP	PTPRT	ENST00000373198	human	ensembl	74_37	-1	known	silent	c.3345	p.A1115	0.998	pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_MAM_dom,pfam_Fibronectin_type3,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_MAM_dom,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_MAM_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom,prints_Tyr_Pase_rcpt/non-rcpt,prints_MAM_dom	-	no_errors	PTPRT	HGNC	ENSG00000196090	tier1	-	-	67	0	0.00	41	16	28.07	60	0	0.00	39	20	33.33
OR2G2	0	genome.wustl.edu	37	1	247752530	247752530	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	1	247752530	247752530	C	A	SNP	OR2G2	ENST00000320065	human	ensembl	74_37	+1	known	missense	c.869	p.P290H	0.989	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2G2	HGNC	ENSG00000177489	tier1	-	-	93	0	0.00	43	16	27.12	102	0	0.00	64	29	31.18
C6orf165	0	genome.wustl.edu	37	6	88120317	88120317	+	Silent	SNP	C	C	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	6	88120317	88120317	C	G	SNP	C6orf165	ENST00000369562	human	ensembl	74_37	+1	known	silent	c.123	p.V41	0.863	NULL	pfam_DUF3508	-	no_errors	C6ORF165	Uniprot_gn	ENSG00000272514	tier1	-	-	93	0	0.00	57	23	28.75	114	0	0.00	119	48	28.74
COX16	0	genome.wustl.edu	37	14	70795938	70795938	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	14	70795938	70795938	C	T	SNP	COX16	ENST00000389912	human	ensembl	74_37	-1	known	missense	c.157	p.E53K	0.998	NULL	NULL	-	no_errors	COX16	HGNC	ENSG00000133983	tier1	-	-	37	0	0.00	28	8	22.22	42	0	0.00	62	12	16.22
C12orf55	0	genome.wustl.edu	37	12	97045392	97045392	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	12	97045392	97045392	G	T	SNP	C12orf55	ENST00000524981	human	ensembl	74_37	+1	putative	missense	c.4899	p.W1633C	1.000	NULL	superfamily_Fibronectin_type3	-	no_errors	C12orf55	HGNC	ENSG00000188596	tier1	-	-	225	0	0.00	159	34	17.62	146	0	0.00	188	29	13.36
ATRX	0	genome.wustl.edu	37	X	76939959	76939959	+	Nonsense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	X	76939959	76939959	C	T	SNP	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	nonsense	c.789	p.W263*	1.000	superfamily_Znf_FYVE_PHD	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	119	0	0.00	38	26	40.62	118	0	0.00	83	37	30.83
MYT1L	0	genome.wustl.edu	37	2	1947094	1947094	+	Nonsense_Mutation	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	2	1947094	1947094	A	T	SNP	MYT1L	ENST00000399161	human	ensembl	74_37	-1	known	nonsense	c.165	p.C55*	0.997	pfam_Znf_C2HC	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1L	HGNC	ENSG00000186487	tier1	-	-	71	0	0.00	36	22	37.93	57	0	0.00	23	18	43.90
MLIP	0	genome.wustl.edu	37	6	54002429	54002429	+	Missense_Mutation	SNP	T	T	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	6	54002429	54002429	T	G	SNP	MLIP	ENST00000502396	human	ensembl	74_37	+1	putative	missense	c.1562	p.M521R	0.001	NULL	NULL	-	no_errors	MLIP	HGNC	ENSG00000146147	tier1	-	-	20	0	0.00	15	4	21.05	43	0	0.00	55	8	12.70
UNC93B1	0	genome.wustl.edu	37	11	67764078	67764078	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	67764078	67764078	C	T	SNP	UNC93B1	ENST00000227471	human	ensembl	74_37	-1	known	missense	c.1081	p.A361T	0.773	NULL	pfam_Ion_channel_UNC-93,superfamily_MFS_dom_general_subst_transpt	-	no_errors	UNC93B1	HGNC	ENSG00000110057	tier1	-	-	20	0	0.00	12	6	33.33	102	0	0.00	72	15	17.24
OR51S1	0	genome.wustl.edu	37	11	4869965	4869965	+	Silent	SNP	A	A	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	4869965	4869965	A	G	SNP	OR51S1	ENST00000322101	human	ensembl	74_37	-1	known	silent	c.474	p.F158	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR51S1	HGNC	ENSG00000176922	tier1	-	-	33	0	0.00	27	7	20.00	94	0	0.00	45	18	27.69
GBP4	0	genome.wustl.edu	37	1	89660991	89660991	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	1	89660991	89660991	C	T	SNP	GBP4	ENST00000355754	human	ensembl	74_37	-1	known	missense	c.352	p.D118N	0.997	pfam_Guanylate-bd_N,superfamily_P-loop_NTPase	pfam_Guanylate-bd_C,pfam_Guanylate-bd_N,superfamily_Guanylate-bd_C,superfamily_P-loop_NTPase	-	no_errors	GBP4	HGNC	ENSG00000162654	tier1	-	-	70	0	0.00	42	28	40.00	127	0	0.00	81	13	13.83
LPL	0	genome.wustl.edu	37	8	19819651	19819651	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	8	19819651	19819651	G	C	SNP	LPL	ENST00000311322	human	ensembl	74_37	+1	known	missense	c.1348	p.V450L	0.140	pirsf_Lipoprotein_lipase_LIPH,pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,prints_Lipo_Lipase,pfscan_PLAT/LH2_dom,tigrfam_Lipo_Lipase	pirsf_Lipoprotein_lipase_LIPH,pfam_Lipase_N,pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,prints_Lipo_Lipase,prints_Lipase,pfscan_PLAT/LH2_dom,tigrfam_Lipo_Lipase	-	no_errors	LPL	HGNC	ENSG00000175445	tier1	-	-	33	0	0.00	16	10	38.46	106	0	0.00	68	29	29.90
ZDHHC4	0	genome.wustl.edu	37	7	6621842	6621842	+	Silent	SNP	A	A	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	7	6621842	6621842	A	G	SNP	ZDHHC4	ENST00000335965	human	ensembl	74_37	+1	known	silent	c.330	p.V110	0.630	NULL	pfam_Znf_DHHC_palmitoyltrfase,superfamily_Cyt_c_Oxase_su1_dom,pfscan_Znf_DHHC_palmitoyltrfase	-	no_errors	ZDHHC4	HGNC	ENSG00000136247	tier1	-	-	96	0	0.00	57	24	29.63	117	0	0.00	81	22	21.36
DLX4	0	genome.wustl.edu	37	17	48050587	48050587	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	17	48050587	48050587	C	A	SNP	DLX4	ENST00000240306	human	ensembl	74_37	+1	known	missense	c.434	p.P145H	1.000	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,prints_Homeobox_metazoa,pfscan_Homeobox_dom	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,prints_HTH_motif,prints_Homeobox_metazoa,pfscan_Homeobox_dom	-	no_errors	DLX4	HGNC	ENSG00000108813	tier1	-	-	32	0	0.00	26	13	33.33	19	0	0.00	13	3	18.75
CYP4F11	0	genome.wustl.edu	37	19	16034891	16034891	+	Missense_Mutation	SNP	T	T	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	19	16034891	16034891	T	C	SNP	CYP4F11	ENST00000248041	human	ensembl	74_37	-1	known	missense	c.649	p.K217E	0.999	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450,prints_Cyt_P450_E_grp-II	-	no_errors	CYP4F11	HGNC	ENSG00000171903	tier1	-	-	63	0	0.00	43	9	17.31	75	0	0.00	45	7	13.46
HK2	0	genome.wustl.edu	37	2	75115175	75115175	+	Missense_Mutation	SNP	C	C	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	2	75115175	75115175	C	G	SNP	HK2	ENST00000290573	human	ensembl	74_37	+1	known	missense	c.2365	p.Q789E	1.000	pfam_Hexokinase_C	pfam_Hexokinase_C,pfam_Hexokinase_N,prints_Hexokinase	-	no_errors	HK2	HGNC	ENSG00000159399	tier1	-	-	34	0	0.00	17	6	26.09	60	0	0.00	44	18	29.03
BEND2	0	genome.wustl.edu	37	X	18189140	18189140	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	X	18189140	18189140	A	T	SNP	BEND2	ENST00000380033	human	ensembl	74_37	-1	known	missense	c.2166	p.N722K	0.030	pfam_BEN_domain	pfam_BEN_domain	-	no_errors	BEND2	HGNC	ENSG00000177324	tier1	-	-	63	0	0.00	39	9	18.75	140	0	0.00	89	20	18.35
PIK3CA	0	genome.wustl.edu	37	3	178947220	178947220	+	Missense_Mutation	SNP	A	A	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	3	178947220	178947220	A	G	SNP	PIK3CA	ENST00000263967	human	ensembl	74_37	+1	known	missense	c.2656	p.K886E	1.000	pfam_PI3/4_kinase_cat_dom,superfamily_Kinase-like_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_dom,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	tier1	-	-	92	0	0.00	93	18	16.22	88	1	1.12	104	25	19.38
TEAD4	0	genome.wustl.edu	37	12	3121377	3121377	+	Nonsense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	12	3121377	3121377	C	T	SNP	TEAD4	ENST00000443986	human	ensembl	74_37	+1	known	nonsense	c.268	p.R90*	0.094	smart_TEA/ATTS	pfam_TEA/ATTS,smart_TEA/ATTS	-	no_errors	TEAD4	HGNC	ENSG00000197905	tier1	rs112112805	-	33	0	0.00	12	6	33.33	75	0	0.00	31	9	22.50
CELP	0	genome.wustl.edu	37	9	135961673	135961673	+	R	SNP	T	T	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	9	135961673	135961673	T	C	SNP	CELP	ENST00000411440	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CELP	HGNC	ENSG00000170827	tier1	-	-	21	0	0.00	27	6	18.18	53	0	0.00	40	9	18.37
MUC16	0	genome.wustl.edu	37	19	9070223	9070223	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	19	9070223	9070223	G	T	SNP	MUC16	ENST00000397910	human	ensembl	74_37	-1	known	missense	c.17223	p.H5741Q	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_SEA_dom	-	no_errors	MUC16	HGNC	ENSG00000181143	tier1	-	-	183	0	0.00	122	22	15.28	93	0	0.00	66	9	12.00
KIAA1731	0	genome.wustl.edu	37	11	93456287	93456287	+	Missense_Mutation	SNP	A	A	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	93456287	93456287	A	G	SNP	KIAA1731	ENST00000411936	human	ensembl	74_37	+1	known	missense	c.6028	p.I2010V	0.000	NULL	NULL	-	no_errors	KIAA1731	HGNC	ENSG00000166004	tier1	-	-	23	0	0.00	14	5	26.32	71	0	0.00	60	29	32.58
101928757	0	genome.wustl.edu	37	10	17875749	17875749	+	Missense_Mutation	SNP	T	T	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	10	17875749	17875749	T	C	SNP	101928757	ENST00000457317	human	ensembl	74_37	+1	known	missense	c.713	p.L238S	1.000	pfam_C-type_lectin,superfamily_C-type_lectin_fold,smart_C-type_lectin,pfscan_C-type_lectin	pfam_C-type_lectin,pfam_FN_type2_col-bd,pfam_Ricin_B_lectin,pfam_Herpes_UL45-like,superfamily_Ricin_B_lectin,superfamily_C-type_lectin_fold,superfamily_Kringle-like,smart_Ricin_B_lectin,smart_FN_type2_col-bd,smart_C-type_lectin,pfscan_FN_type2_col-bd,pfscan_C-type_lectin,pfscan_Ricin_B_lectin,prints_AntifreezeII	-	no_errors	MRC1L1	Clone_based_vega_gene	ENSG00000183748	tier1	-	-	99	0	0.00	51	14	21.54	109	1	0.91	53	18	25.35
SIRT3	0	genome.wustl.edu	37	11	218993	218993	+	Nonsense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	218993	218993	G	A	SNP	SIRT3	ENST00000382743	human	ensembl	74_37	-1	known	nonsense	c.1018	p.R340*	1.000	pirsf_D-dep_deAcase_SIR2_class_I,pfscan_Ssirtuin_cat_dom	pfam_Sirtuin,pirsf_D-dep_deAcase_SIR2_class_I,pfscan_Ssirtuin_cat_dom	-	no_errors	SIRT3	HGNC	ENSG00000142082	tier1	rs199874973	-	72	0	0.00	38	8	17.39	34	0	0.00	31	8	20.51
GABRA5	0	genome.wustl.edu	37	15	27188460	27188460	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	15	27188460	27188460	G	A	SNP	GABRA5	ENST00000335625	human	ensembl	74_37	+1	known	missense	c.976	p.V326M	0.999	pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,prints_GABAAa_rcpt,prints_GABAA_rcpt,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAAa_rcpt,prints_GABAA_rcpt,prints_GABBAa5_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRA5	HGNC	ENSG00000186297	tier1	-	-	46	0	0.00	27	7	20.59	40	0	0.00	38	14	26.92
FREM2	0	genome.wustl.edu	37	13	39450410	39450410	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	13	39450410	39450410	C	A	SNP	FREM2	ENST00000280481	human	ensembl	74_37	+1	known	missense	c.8435	p.T2812N	0.958	NULL	pfam_Calx_beta,superfamily_Cadherin-like,smart_Calx_beta	-	no_errors	FREM2	HGNC	ENSG00000150893	tier1	-	-	47	0	0.00	57	9	13.64	43	0	0.00	88	24	21.43
TOP2A	0	genome.wustl.edu	37	17	38551786	38551786	+	Missense_Mutation	SNP	T	T	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	17	38551786	38551786	T	A	SNP	TOP2A	ENST00000423485	human	ensembl	74_37	-1	known	missense	c.3726	p.E1242D	1.000	NULL	pfam_Topo_IIA_A/C,pfam_Topo_IIA_bsu_dom2,pfam_DTHCT,pfam_HATPase_ATP-bd,superfamily_Topo_IIA_like_dom,superfamily_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,smart_Topo_IIA,smart_Topo_IIA_A/C,prints_TopoII_euk,prints_Topo_IIA,prints_Transcrpt_fac_NFYB/HAP3	-	no_errors	TOP2A	HGNC	ENSG00000131747	tier1	-	-	44	0	0.00	38	10	20.83	93	0	0.00	82	15	15.46
PRSS1	0	genome.wustl.edu	37	7	142459736	142459736	+	Silent	SNP	G	G	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	7	142459736	142459736	G	T	SNP	PRSS1	ENST00000311737	human	ensembl	74_37	+1	known	silent	c.312	p.L104	1.000	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	PRSS1	HGNC	ENSG00000204983	tier1	-	-	104	1	0.95	94	14	12.84	83	0	0.00	61	10	14.08
NEB	0	genome.wustl.edu	37	2	152521904	152521904	+	Silent	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	2	152521904	152521904	G	A	SNP	NEB	ENST00000397345	human	ensembl	74_37	-1	known	silent	c.5181	p.Y1727	0.000	smart_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_Adhesion_dom,superfamily_6-PGluconate_DH_C-like,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_Nebulin	-	no_errors	NEB	HGNC	ENSG00000183091	tier1	rs35016946	-	257	0	0.00	137	64	31.53	86	0	0.00	35	25	41.67
MOBP	0	genome.wustl.edu	37	3	39555017	39555017	+	R	DEL	G	G	-			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	3	39555017	39555017	G	-	DEL	MOBP	ENST00000479860	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.091	-	-	-	no_errors	MOBP	HGNC	ENSG00000168314	tier1			42	0	0.00	44	6	12.00	61	0	0.00	54	19	26.03
KIAA1109	0	genome.wustl.edu	37	4	123188042	123188042	+	Frame_Shift_Del	DEL	T	T	-			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	-	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	4	123188042	123188042	T	-	DEL	KIAA1109	ENST00000264501	human	ensembl	74_37	+1	known	frame_shift_del	c.7422	p.L2475fs	0.803	NULL	pfam_Fragile_site-assoc_C	-	no_errors	KIAA1109	HGNC	ENSG00000138688	tier1			51	0	0.00	24	16	40.00	95	0	0.00	57	24	29.63
PROSER1	0	genome.wustl.edu	37	13	39587561	39587562	+	Frame_Shift_Del	DEL	CA	CA	-			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	CA	CA	CA	-	CA	CA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	13	39587561	39587562	CA	-	DEL	PROSER1	ENST00000352251	human	ensembl	74_37	-1	known	frame_shift_del	c.1828_1827	p.E610fs	1.000:0.992	NULL	NULL	-	no_errors	PROSER1	HGNC	ENSG00000120685	tier1			97	0	0.00	100	23	18.70	107	0	0.00	167	39	18.93
EBF1	0	genome.wustl.edu	37	5	158126125	158126126	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	AG	AG	AG	-	AG	AG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	5	158126125	158126126	AG	-	DEL	EBF1	ENST00000313708	human	ensembl	74_37	-1	known	frame_shift_del	c.1770_1769	p.P590fs	1.000:1.000	NULL	pfam_IPT,superfamily_Ig_E-set,superfamily_bHLH_dom,smart_IPT	-	no_errors	EBF1	HGNC	ENSG00000164330	tier1			45	0	0.00	55	12	17.91	67	0	0.00	63	16	20.25
MRVI1	0	genome.wustl.edu	37	11	10653562	10653562	+	Frame_Shift_Del	DEL	A	A	-			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	10653562	10653562	A	-	DEL	MRVI1	ENST00000421747	human	ensembl	74_37	-1	known	frame_shift_del	c.349	p.S117fs	0.990	NULL	pfam_MRVI1	-	no_errors	MRVI1	HGNC	ENSG00000072952	tier1			58	0	0.00	32	7	17.95	106	0	0.00	85	23	21.30
ADAMTS8	0	genome.wustl.edu	37	11	130275593	130275593	+	Missense_Mutation	SNP	A	A	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	130275593	130275593	A	G	SNP	ADAMTS8	ENST00000257359	human	ensembl	74_37	-1	known	missense	c.2530	p.C844R	1.000	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_ADAM_spacer1,pfam_Peptidase_M12B_N,pfam_Peptidase_M12B,pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_ADAM_Cys-rich,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Pept_M12B_ADAM-TS8,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS8	HGNC	ENSG00000134917	tier1	-	-	41	0	0.00	18	5	21.74	8	0	0.00	3	4	57.14
CDKN1A	0	genome.wustl.edu	37	6	36652002	36652002	+	Missense_Mutation	SNP	A	A	C			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	6	36652002	36652002	A	C	SNP	CDKN1A	ENST00000448526	human	ensembl	74_37	+1	known	missense	c.226	p.I76L	0.000	pfam_CDI	pfam_CDI	-	no_errors	CDKN1A	HGNC	ENSG00000124762	tier1	-	-	55	0	0.00	37	9	19.57	20	0	0.00	7	3	30.00
SPANXC	0	genome.wustl.edu	37	X	140335820	140335820	+	Missense_Mutation	SNP	T	T	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	X	140335820	140335820	T	A	SNP	SPANXC	ENST00000358993	human	ensembl	74_37	-1	known	missense	c.124	p.M42L	0.004	pfam_SPANX_prot	pfam_SPANX_prot	-	no_errors	SPANXC	HGNC	ENSG00000198573	tier1	-	-	294	1	0.34	197	48	19.59	67	0	0.00	61	4	6.15
LILRB5	0	genome.wustl.edu	37	19	54758275	54758275	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	19	54758275	54758275	G	T	SNP	LILRB5	ENST00000450632	human	ensembl	74_37	-1	known	missense	c.1232	p.P411H	0.000	NULL	smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	LILRB5	HGNC	ENSG00000105609	tier1	-	-	46	0	0.00	32	5	13.51	91	0	0.00	55	6	9.84
DYNC2H1	0	genome.wustl.edu	37	11	103191767	103191767	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	11	103191767	103191767	A	T	SNP	DYNC2H1	ENST00000398093	human	ensembl	74_37	+1	known	missense	c.11756	p.D3919V	1.000	pfam_Dynein_heavy_dom	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DYNC2H1	HGNC	ENSG00000187240	tier1	-	-	68	0	0.00	54	10	15.62	48	0	0.00	60	4	6.15
FERMT1	0	genome.wustl.edu	37	20	6096550	6096550	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	20	6096550	6096550	C	T	SNP	FERMT1	ENST00000217289	human	ensembl	74_37	-1	known	missense	c.293	p.R98H	1.000	smart_Band_41_domain	pfam_FERM_central,pfam_FERM_N,superfamily_FERM_central,smart_Band_41_domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	FERMT1	HGNC	ENSG00000101311	tier1	rs137862671	GMAF=0.0005	39	0	0.00	23	8	25.81	85	0	0.00	65	5	7.14
LOC100996870	0	genome.wustl.edu	37	9	66468909	66468909	+	R	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	9	66468909	66468909	G	A	SNP	LOC100996870	ENST00000424345	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.065	-	-	-	no_errors	RP11-262H14.1	Clone_based_vega_gene	ENSG00000238113	tier1	rs78672302	-	11	0	0.00	10	5	33.33	46	1	2.13	33	8	19.51
JPH3	0	genome.wustl.edu	37	16	87678395	87678395	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	16	87678395	87678395	G	A	SNP	JPH3	ENST00000284262	human	ensembl	74_37	+1	known	missense	c.914	p.R305H	1.000	pirsf_Junctophilin,pfam_MORN,smart_MORN	pirsf_Junctophilin,pfam_MORN,smart_MORN	-	no_errors	JPH3	HGNC	ENSG00000154118	tier1	-	-	79	0	0.00	27	8	22.86	7	0	0.00	4	0	0.00
SPOCK3	0	genome.wustl.edu	37	4	168155291	168155292	+	Frame_Shift_Del	DEL	CA	CA	-			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	CA	CA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	4	168155291	168155292	CA	-	DEL	SPOCK3	ENST00000357154	human	ensembl	74_37	-1	known	frame_shift_del	c.34_33	p.A12fs	1.000:1.000	NULL	pfam_SPARC/Testican_Ca-bd-dom,pfam_Thyroglobulin_1,pfam_Kazal_dom,superfamily_Thyroglobulin_1,smart_Kazal_dom,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1	-	no_errors	SPOCK3	HGNC	ENSG00000196104	tier1			59	0	0.00	23	3	11.54	8	0	0.00	5	0	0.00
MAML3	0	genome.wustl.edu	37	4	140811066	140811066	+	Splice_Site	SNP	C	C	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	4	140811066	140811066	C	T	SNP	MAML3	ENST00000398940	human	ensembl	74_37	-1	known	splice_site	c.109-1	e2-1	1.000	-	-	-	no_errors	MAML3	HGNC	ENSG00000196782	tier1	-	-	62	0	0.00	60	6	9.09	1	0	0.00	1	0	0.00
VIM	0	genome.wustl.edu	37	10	17271377	17271377	+	R	SNP	T	T	G			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	10	17271377	17271377	T	G	SNP	VIM	ENST00000478317	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	VIM	HGNC	ENSG00000026025	tier1	-	-	22	0	0.00	5	7	58.33	3	0	0.00	0	2	100.00
PRSS16	0	genome.wustl.edu	37	6	27219026	27219026	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	6	27219026	27219026	A	T	SNP	PRSS16	ENST00000230582	human	ensembl	74_37	+1	known	missense	c.700	p.I234F	0.007	pfam_Peptidase_S28	pfam_Peptidase_S28	-	no_errors	PRSS16	HGNC	ENSG00000112812	tier1	-	-	69	0	0.00	47	8	14.55	59	0	0.00	33	2	5.56
ZNF608	0	genome.wustl.edu	37	5	124079849	124079849	+	Silent	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	5	124079849	124079849	G	A	SNP	ZNF608	ENST00000306315	human	ensembl	74_37	-1	known	silent	c.834	p.N278	1.000	NULL	NULL	-	no_errors	ZNF608	HGNC	ENSG00000168916	tier1	-	-	30	0	0.00	20	4	16.67	60	0	0.00	30	3	8.82
ACO1	0	genome.wustl.edu	37	9	32419050	32419050	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	9	32419050	32419050	G	A	SNP	ACO1	ENST00000309951	human	ensembl	74_37	+1	known	missense	c.673	p.E225K	1.000	pfam_Acoase/IPM_deHydtase_lsu_aba,superfamily_Acoase/IPM_deHydtase_lsu_aba,prints_Acoase/IPM_deHydtase_lsu_aba,tigrfam_Aconitase/Fe_reg_prot_2	pfam_Acoase/IPM_deHydtase_lsu_aba,pfam_AconitaseA/IPMdHydase_ssu_swvl,superfamily_Acoase/IPM_deHydtase_lsu_aba,superfamily_Aconitase/3IPM_dehydase_swvl,prints_Acoase/IPM_deHydtase_lsu_aba,tigrfam_Aconitase/Fe_reg_prot_2	-	no_errors	ACO1	HGNC	ENSG00000122729	tier1	-	-	61	0	0.00	19	6	24.00	57	0	0.00	21	2	8.70
ADRA2B	0	genome.wustl.edu	37	2	96781300	96781300	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A2OT-01A-11D-A21Q-09	TCGA-HB-A2OT-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9b94fd39-a2ed-4f84-a977-ee5190378c1f	fda78838-677d-481c-9ac5-e17e40a974aa	2	96781300	96781300	G	T	SNP	ADRA2B	ENST00000409345	human	ensembl	74_37	-1	known	missense	c.589	p.L197M	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_ADR_fam	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_ADRA2B_rcpt,prints_GPCR_Rhodpsn,prints_ADR_fam	-	no_errors	ADRA2B	HGNC	ENSG00000222040	tier1	-	-	23	0	0.00	14	7	33.33	71	0	0.00	56	3	5.08