Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ZNF782	0	genome.wustl.edu	37	9	99607255	99607255	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	99607255	99607255	T	C	SNP	ZNF782	ENST00000481138	human	ensembl	74_37	-1	known	missense	c.59	p.E20G	0.996	pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF782	HGNC	ENSG00000196597	tier1	-	-	94	0	0.00	101	65	39.16	16	0	0.00	13	8	38.10
OSBPL8	0	genome.wustl.edu	37	12	76786379	76786379	+	Missense_Mutation	SNP	T	T	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	12	76786379	76786379	T	G	SNP	OSBPL8	ENST00000261183	human	ensembl	74_37	-1	known	missense	c.911	p.H304P	1.000	NULL	pfam_Oxysterol-bd,pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	OSBPL8	HGNC	ENSG00000091039	tier1	-	-	37	0	0.00	23	12	34.29	111	0	0.00	47	15	24.19
MCM10	0	genome.wustl.edu	37	10	13237231	13237231	+	Missense_Mutation	SNP	C	C	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	13237231	13237231	C	G	SNP	MCM10	ENST00000484800	human	ensembl	74_37	+1	known	missense	c.1939	p.P647A	1.000	pfam_Rep_factor_Mcm10	pfam_Rep_factor_Mcm10,pfam_Znf_Mcm10/DnaG	-	no_errors	MCM10	HGNC	ENSG00000065328	tier1	-	-	16	0	0.00	7	6	46.15	45	0	0.00	38	28	41.79
ANXA1	0	genome.wustl.edu	37	9	75775261	75775261	+	Missense_Mutation	SNP	T	T	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	75775261	75775261	T	A	SNP	ANXA1	ENST00000257497	human	ensembl	74_37	+1	known	missense	c.353	p.F118Y	1.000	pfam_Annexin_repeat	pfam_Annexin_repeat,smart_Annexin_repeat,prints_Annexin,prints_AnnexinI	-	no_errors	ANXA1	HGNC	ENSG00000135046	tier1	-	-	44	0	0.00	49	22	30.99	101	0	0.00	80	57	41.61
TMEM132D	0	genome.wustl.edu	37	12	130184367	130184367	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	12	130184367	130184367	C	T	SNP	TMEM132D	ENST00000422113	human	ensembl	74_37	-1	known	missense	c.956	p.R319H	0.000	NULL	NULL	-	no_errors	TMEM132D	HGNC	ENSG00000151952	tier1	-	-	37	0	0.00	20	5	20.00	168	0	0.00	94	43	31.39
PKHD1L1	0	genome.wustl.edu	37	8	110437395	110437395	+	Missense_Mutation	SNP	A	A	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	8	110437395	110437395	A	T	SNP	PKHD1L1	ENST00000378402	human	ensembl	74_37	+1	known	missense	c.2779	p.I927F	0.998	NULL	pfam_IPT,pfam_G8_domain,pfam_PA14,superfamily_Ig_E-set,superfamily_Pectin_lyase_fold/virulence,superfamily_Cupredoxin,smart_IPT,smart_PA14,smart_PbH1	-	no_errors	PKHD1L1	HGNC	ENSG00000205038	tier1	-	-	26	0	0.00	41	10	19.61	74	0	0.00	66	18	21.43
LOC101927911	0	genome.wustl.edu	37	17	2865946	2865946	+	R	SNP	T	T	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	2865946	2865946	T	A	SNP	LOC101927911	ENST00000574885	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.995	-	-	-	no_errors	CTD-3060P21.1	Clone_based_vega_gene	ENSG00000262884	tier1	-	-	154	1	0.65	99	22	18.18	83	0	0.00	100	25	20.00
CGN	0	genome.wustl.edu	37	1	151497206	151497206	+	Silent	SNP	A	A	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	1	151497206	151497206	A	G	SNP	CGN	ENST00000271636	human	ensembl	74_37	+1	known	silent	c.1458	p.V486	0.957	NULL	pfam_Myosin_tail	-	no_errors	CGN	HGNC	ENSG00000143375	tier1	-	-	56	0	0.00	43	7	14.00	36	0	0.00	44	8	15.38
DUSP27	0	genome.wustl.edu	37	1	167095964	167095964	+	Silent	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	1	167095964	167095964	C	T	SNP	DUSP27	ENST00000271385	human	ensembl	74_37	+1	known	silent	c.1596	p.N532	1.000	NULL	pfam_Dual-sp_phosphatase_cat-dom,smart_Dual-sp_phosphatase_subgr_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat,prints_Atypical_DUSP,prints_Atypical_DUSP_famA	-	no_errors	DUSP27	HGNC	ENSG00000198842	tier1	-	-	32	0	0.00	20	17	45.95	71	0	0.00	66	46	41.07
LRRC37A6P	0	genome.wustl.edu	37	10	27539404	27539404	+	R	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	27539404	27539404	G	C	SNP	LRRC37A6P	ENST00000284414	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.283	-	-	-	no_errors	LRRC37A6P	HGNC	ENSG00000230445	tier1	-	-	70	0	0.00	45	19	29.69	37	0	0.00	39	19	32.76
SPATA31C1	0	genome.wustl.edu	37	9	90535818	90535818	+	R	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	90535818	90535818	G	C	SNP	SPATA31C1	ENST00000602681	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	SPATA31C1	HGNC	ENSG00000230246	tier1	-	-	260	0	0.00	147	106	41.90	22	0	0.00	19	27	58.70
LOC100132215	0	genome.wustl.edu	37	2	63272396	63272396	+	R	SNP	T	T	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	63272396	63272396	T	G	SNP	LOC100132215	ENST00000412297	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC009501.4	Clone_based_vega_gene	ENSG00000231609	tier1	-	-	32	0	0.00	10	29	74.36	37	0	0.00	15	22	59.46
BRD3	0	genome.wustl.edu	37	9	136905253	136905253	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	136905253	136905253	C	T	SNP	BRD3	ENST00000303407	human	ensembl	74_37	-1	known	missense	c.1546	p.E516K	1.000	NULL	pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain	-	no_errors	BRD3	HGNC	ENSG00000169925	tier1	rs62639321	-	77	0	0.00	19	19	50.00	50	0	0.00	23	18	43.90
EGR2	0	genome.wustl.edu	37	10	64573803	64573803	+	Missense_Mutation	SNP	A	A	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	64573803	64573803	A	C	SNP	EGR2	ENST00000242480	human	ensembl	74_37	-1	known	missense	c.595	p.S199A	0.997	NULL	pfam_DUF3446,pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	EGR2	HGNC	ENSG00000122877	tier1	-	-	82	0	0.00	48	11	18.64	70	0	0.00	36	28	43.75
CDK3	0	genome.wustl.edu	37	17	73998102	73998102	+	Splice_Site	SNP	G	G	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	73998102	73998102	G	A	SNP	CDK3	ENST00000425876	human	ensembl	74_37	+1	known	splice_site	c.195-1	e3-1	1.000	-	-	-	no_errors	CDK3	HGNC	ENSG00000250506	tier1	-	-	89	0	0.00	68	22	24.44	87	0	0.00	120	16	11.68
KIAA1549	0	genome.wustl.edu	37	7	138602589	138602589	+	Missense_Mutation	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	7	138602589	138602589	C	A	SNP	KIAA1549	ENST00000422774	human	ensembl	74_37	-1	known	missense	c.1783	p.V595F	0.001	NULL	NULL	-	no_errors	KIAA1549	HGNC	ENSG00000122778	tier1	-	-	26	0	0.00	4	9	69.23	134	0	0.00	57	46	44.66
C17orf47	0	genome.wustl.edu	37	17	56620335	56620335	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	56620335	56620335	C	T	SNP	C17orf47	ENST00000321691	human	ensembl	74_37	-1	known	missense	c.1213	p.E405K	0.353	NULL	NULL	-	no_errors	C17orf47	HGNC	ENSG00000181013	tier1	-	-	67	0	0.00	84	18	17.65	116	0	0.00	160	23	12.43
MCF2	0	genome.wustl.edu	37	X	138701798	138701798	+	Missense_Mutation	SNP	G	G	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	X	138701798	138701798	G	A	SNP	MCF2	ENST00000370578	human	ensembl	74_37	-1	known	missense	c.1190	p.A397V	0.001	smart_Spectrin/alpha-actinin	pfam_DH-domain,superfamily_DH-domain,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,smart_Spectrin/alpha-actinin,smart_DH-domain,smart_Pleckstrin_homology,pfscan_CRAL-TRIO_dom,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	MCF2	HGNC	ENSG00000101977	tier1	-	-	57	0	0.00	69	25	26.60	78	0	0.00	95	16	14.41
ADORA2A	0	genome.wustl.edu	37	22	24836570	24836570	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	22	24836570	24836570	G	C	SNP	ADORA2A	ENST00000337539	human	ensembl	74_37	+1	known	missense	c.352	p.G118R	0.298	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Adeno_A2A_rcpt,prints_GPCR_Rhodpsn,prints_Adenosn_rcpt	-	no_errors	ADORA2A	HGNC	ENSG00000128271	tier1	-	-	86	0	0.00	66	27	29.03	67	0	0.00	47	29	38.16
ANKRD36BP2	0	genome.wustl.edu	37	2	89104342	89104342	+	R	SNP	A	A	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	89104342	89104342	A	C	SNP	ANKRD36BP2	ENST00000393515	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.011	-	-	-	no_errors	ANKRD36BP2	HGNC	ENSG00000230006	tier1	-	-	77	0	0.00	113	49	30.25	26	0	0.00	17	11	39.29
RYR2	0	genome.wustl.edu	37	1	237806668	237806668	+	Silent	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	1	237806668	237806668	C	T	SNP	RYR2	ENST00000360064	human	ensembl	74_37	+1	known	silent	c.7257	p.S2419	0.943	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_hand_dom,pfscan_MIR_motif	-	no_errors	RYR2	HGNC	ENSG00000198626	tier1	-	-	59	0	0.00	32	21	39.62	109	0	0.00	36	24	40.00
OR5T2	0	genome.wustl.edu	37	11	55999957	55999957	+	Missense_Mutation	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	11	55999957	55999957	C	A	SNP	OR5T2	ENST00000313264	human	ensembl	74_37	-1	known	missense	c.705	p.Q235H	0.001	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5T2	HGNC	ENSG00000181718	tier1	-	-	76	0	0.00	70	40	36.36	22	0	0.00	26	14	35.00
ARHGAP32	0	genome.wustl.edu	37	11	128844161	128844161	+	Missense_Mutation	SNP	C	C	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	11	128844161	128844161	C	G	SNP	ARHGAP32	ENST00000310343	human	ensembl	74_37	-1	known	missense	c.2889	p.E963D	0.996	NULL	pfam_RhoGAP_dom,pfam_SH3_domain,pfam_SH3_2,pfam_Phox,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,superfamily_Phox,smart_SH3_domain,smart_RhoGAP_dom,pfscan_SH3_domain,pfscan_RhoGAP_dom	-	no_errors	ARHGAP32	HGNC	ENSG00000134909	tier1	-	-	35	0	0.00	15	14	48.28	89	0	0.00	36	29	44.62
SPHKAP	0	genome.wustl.edu	37	2	228883262	228883262	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	228883262	228883262	T	C	SNP	SPHKAP	ENST00000392056	human	ensembl	74_37	-1	known	missense	c.2308	p.S770G	0.011	NULL	pfam_AKAP_110_C	-	no_errors	SPHKAP	HGNC	ENSG00000153820	tier1	-	-	51	0	0.00	41	13	24.07	95	1	1.04	47	32	40.51
STOML1	0	genome.wustl.edu	37	15	74280989	74280989	+	Missense_Mutation	SNP	G	G	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	15	74280989	74280989	G	A	SNP	STOML1	ENST00000316900	human	ensembl	74_37	-1	known	missense	c.545	p.P182L	0.328	pfam_Band_7,smart_Band_7,prints_Stomatin	pfam_Band_7,pfam_SCP2_sterol-bd_dom,superfamily_SCP2_sterol-bd_dom,smart_Band_7,prints_Stomatin	-	no_errors	STOML1	HGNC	ENSG00000067221	tier1	-	-	66	0	0.00	34	13	27.66	53	0	0.00	31	14	31.11
ANO4	0	genome.wustl.edu	37	12	101433740	101433740	+	Missense_Mutation	SNP	A	A	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	12	101433740	101433740	A	T	SNP	ANO4	ENST00000392977	human	ensembl	74_37	+1	known	missense	c.905	p.Y302F	1.000	NULL	pfam_Anoctamin	-	no_errors	ANO4	HGNC	ENSG00000151572	tier1	-	-	34	0	0.00	25	9	26.47	98	0	0.00	73	38	33.93
ARID1B	0	genome.wustl.edu	37	6	157256633	157256633	+	Nonsense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	6	157256633	157256633	C	T	SNP	ARID1B	ENST00000367148	human	ensembl	74_37	+1	known	nonsense	c.1921	p.Q641*	1.000	NULL	pfam_DUF3518,pfam_ARID/BRIGHT_D-bd,superfamily_ARID/BRIGHT_D-bd,superfamily_ARM-type_fold,smart_ARID/BRIGHT_D-bd,pfscan_ARID/BRIGHT_D-bd	-	no_errors	ARID1B	HGNC	ENSG00000049618	tier1	-	-	59	0	0.00	34	55	61.80	130	0	0.00	55	78	58.65
RANBP3	0	genome.wustl.edu	37	19	5918597	5918597	+	Silent	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	19	5918597	5918597	G	C	SNP	RANBP3	ENST00000340578	human	ensembl	74_37	-1	known	silent	c.1383	p.A461	0.010	pfam_Ran_bind_dom,smart_Ran_bind_dom,pfscan_Ran_bind_dom	pfam_Ran_bind_dom,smart_Ran_bind_dom,pfscan_Ran_bind_dom	-	no_errors	RANBP3	HGNC	ENSG00000031823	tier1	-	-	61	0	0.00	40	27	40.30	35	0	0.00	56	27	32.53
PAPPA	0	genome.wustl.edu	37	9	119124887	119124887	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	119124887	119124887	T	C	SNP	PAPPA	ENST00000328252	human	ensembl	74_37	+1	known	missense	c.4364	p.V1455A	0.174	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	pfam_Sushi_SCR_CCP,pfam_Notch_dom,pfam_Peptidase_M43,superfamily_ConA-like_lec_gl_sf,superfamily_Sushi_SCR_CCP,superfamily_Fibronectin_type3,superfamily_Notch_dom,smart_LamG-like,smart_Notch_dom,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP,tigrfam_Myxo_disulph_rpt	-	no_errors	PAPPA	HGNC	ENSG00000182752	tier1	-	-	26	0	0.00	29	27	48.21	98	0	0.00	72	66	47.83
C17orf47	0	genome.wustl.edu	37	17	56620182	56620182	+	Missense_Mutation	SNP	C	C	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	56620182	56620182	C	G	SNP	C17orf47	ENST00000321691	human	ensembl	74_37	-1	known	missense	c.1366	p.D456H	0.528	NULL	NULL	-	no_errors	C17orf47	HGNC	ENSG00000181013	tier1	-	-	52	0	0.00	43	9	17.31	95	0	0.00	110	34	23.61
ODAM	0	genome.wustl.edu	37	4	71063870	71063870	+	Missense_Mutation	SNP	G	G	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	4	71063870	71063870	G	T	SNP	ODAM	ENST00000396094	human	ensembl	74_37	+1	known	missense	c.371	p.S124I	0.001	NULL	NULL	-	no_errors	ODAM	HGNC	ENSG00000109205	tier1	-	-	18	0	0.00	38	8	17.39	108	0	0.00	84	33	28.21
DJA4	0	genome.wustl.edu	37	15	78565508	78565508	+	Missense_Mutation	SNP	C	C	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	15	78565508	78565508	C	G	SNP	DJA4	ENST00000394855	human	ensembl	74_37	+1	known	missense	c.472	p.L158V	0.995	pfam_HSP_DnaJ_Cys-rich_dom,superfamily_HSP40/DnaJ_pept-bd,pfscan_HSP_DnaJ_Cys-rich_dom	pfam_DnaJ_domain,pfam_DnaJ_C,pfam_HSP_DnaJ_Cys-rich_dom,superfamily_DnaJ_domain,superfamily_HSP40/DnaJ_pept-bd,superfamily_HSP_DnaJ_Cys-rich_dom,smart_DnaJ_domain,pfscan_DnaJ_domain,pfscan_HSP_DnaJ_Cys-rich_dom,prints_DnaJ_domain	-	no_errors	DJA4	HGNC	ENSG00000140403	tier1	-	-	34	0	0.00	7	19	73.08	92	0	0.00	63	69	52.27
ZNF423	0	genome.wustl.edu	37	16	49670663	49670663	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	16	49670663	49670663	G	C	SNP	ZNF423	ENST00000262383	human	ensembl	74_37	-1	known	missense	c.2400	p.I800M	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF423	HGNC	ENSG00000102935	tier1	-	-	53	0	0.00	38	9	19.15	50	0	0.00	95	25	20.83
KLHL1	0	genome.wustl.edu	37	13	70371041	70371041	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	13	70371041	70371041	C	T	SNP	KLHL1	ENST00000377844	human	ensembl	74_37	-1	known	missense	c.1468	p.G490R	1.000	pfam_Kelch_1,smart_Kelch_1	pfam_Kelch_1,pfam_Kelch_2,pfam_BACK,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like	-	no_errors	KLHL1	HGNC	ENSG00000150361	tier1	-	-	53	0	0.00	129	27	17.20	74	0	0.00	120	20	14.18
ALOX5	0	genome.wustl.edu	37	10	45939225	45939225	+	Silent	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	45939225	45939225	C	A	SNP	ALOX5	ENST00000374391	human	ensembl	74_37	+1	known	silent	c.1623	p.T541	0.000	pfam_LipOase_C,superfamily_LipOase_C	pfam_LipOase_C,pfam_PLAT/LH2_dom,superfamily_LipOase_C,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,prints_LipOase_mml,prints_LipOase_C,pfscan_PLAT/LH2_dom	-	no_errors	ALOX5	HGNC	ENSG00000012779	tier1	-	-	75	0	0.00	32	24	42.86	31	0	0.00	16	9	36.00
PPP1R3A	0	genome.wustl.edu	37	7	113518694	113518694	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	7	113518694	113518694	T	C	SNP	PPP1R3A	ENST00000284601	human	ensembl	74_37	-1	known	missense	c.2453	p.E818G	0.000	NULL	pfam_CBM_21,pfscan_CBM_21	-	no_errors	PPP1R3A	HGNC	ENSG00000154415	tier1	-	-	68	0	0.00	55	16	22.54	99	0	0.00	70	38	35.19
LOC100132215	0	genome.wustl.edu	37	2	63272423	63272423	+	R	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	63272423	63272423	C	T	SNP	LOC100132215	ENST00000412297	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC009501.4	Clone_based_vega_gene	ENSG00000231609	tier1	-	-	27	0	0.00	16	19	54.29	37	0	0.00	17	20	54.05
FAM47C	0	genome.wustl.edu	37	X	37028953	37028953	+	Missense_Mutation	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	X	37028953	37028953	C	A	SNP	FAM47C	ENST00000358047	human	ensembl	74_37	+1	known	missense	c.2470	p.L824I	0.018	NULL	NULL	-	no_errors	FAM47C	HGNC	ENSG00000198173	tier1	-	-	102	0	0.00	79	56	41.48	37	0	0.00	28	25	47.17
GNL3L	0	genome.wustl.edu	37	X	54578772	54578772	+	Missense_Mutation	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	X	54578772	54578772	C	A	SNP	GNL3L	ENST00000336470	human	ensembl	74_37	+1	known	missense	c.1229	p.P410H	1.000	NULL	pfam_GTP_binding_domain,pfam_Fe2_transport_prot_B_N,superfamily_P-loop_NTPase,prints_GTP_binding_domain	-	no_errors	GNL3L	HGNC	ENSG00000130119	tier1	-	-	58	0	0.00	86	22	20.37	71	0	0.00	68	32	32.00
PCMTD2	0	genome.wustl.edu	37	20	62896684	62896684	+	Missense_Mutation	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	20	62896684	62896684	C	A	SNP	PCMTD2	ENST00000308824	human	ensembl	74_37	+1	known	missense	c.484	p.R162S	1.000	pfam_PCMT	pfam_PCMT	-	no_errors	PCMTD2	HGNC	ENSG00000203880	tier1	-	-	170	0	0.00	93	69	42.59	87	0	0.00	43	47	52.22
SP140	0	genome.wustl.edu	37	2	231112669	231112669	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	231112669	231112669	T	C	SNP	SP140	ENST00000392045	human	ensembl	74_37	+1	known	missense	c.781	p.Y261H	0.000	NULL	pfam_Sp100,pfam_SAND_dom,pfam_Bromodomain,pfam_Znf_PHD-finger,superfamily_SAND_dom-like,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,smart_SAND_dom,smart_Znf_PHD,smart_Bromodomain,pfscan_Znf_PHD-finger,pfscan_SAND_dom,pfscan_Bromodomain	-	no_errors	SP140	HGNC	ENSG00000079263	tier1	-	-	13	0	0.00	14	6	30.00	74	0	0.00	36	16	30.77
PSB	0	genome.wustl.edu	37	19	50839923	50839923	+	R	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	19	50839923	50839923	C	T	SNP	PSB	ENST00000527780	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	PSB	HGNC	ENSG00000131401	tier1	-	-	70	0	0.00	36	45	55.56	96	0	0.00	55	34	38.20
TFDP2	0	genome.wustl.edu	37	3	141713978	141713978	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	3	141713978	141713978	T	C	SNP	TFDP2	ENST00000489671	human	ensembl	74_37	-1	known	missense	c.192	p.I64M	1.000	pirsf_Transcrpt_fac_DP	pfam_Transc_factor_DP_C,pfam_E2F_TDP,pirsf_Transcrpt_fac_DP	-	no_errors	TFDP2	HGNC	ENSG00000114126	tier1	-	-	44	0	0.00	81	14	14.74	59	0	0.00	83	20	19.42
ACSF2	0	genome.wustl.edu	37	17	48548432	48548432	+	Missense_Mutation	SNP	A	A	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	48548432	48548432	A	C	SNP	ACSF2	ENST00000300441	human	ensembl	74_37	+1	known	missense	c.1259	p.H420P	0.077	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSF2	HGNC	ENSG00000167107	tier1	-	-	49	0	0.00	39	7	15.22	57	0	0.00	67	16	19.28
PROKR2	0	genome.wustl.edu	37	20	5294713	5294713	+	Silent	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	20	5294713	5294713	C	T	SNP	PROKR2	ENST00000217270	human	ensembl	74_37	-1	known	silent	c.303	p.L101	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_NPY_rcpt	-	no_errors	PROKR2	HGNC	ENSG00000101292	tier1	-	-	104	0	0.00	85	29	25.44	74	1	1.33	47	25	34.25
DMD	0	genome.wustl.edu	37	X	32663086	32663086	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	X	32663086	32663086	G	C	SNP	DMD	ENST00000357033	human	ensembl	74_37	-1	known	missense	c.1144	p.H382D	1.000	pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin,pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	DMD	HGNC	ENSG00000198947	tier1	-	-	45	0	0.00	41	33	44.59	93	0	0.00	67	34	33.66
THEMIS	0	genome.wustl.edu	37	6	128176258	128176258	+	Missense_Mutation	SNP	A	A	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	6	128176258	128176258	A	T	SNP	THEMIS	ENST00000543064	human	ensembl	74_37	-1	known	missense	c.167	p.V56D	1.000	NULL	NULL	-	no_errors	THEMIS	HGNC	ENSG00000172673	tier1	-	-	44	0	0.00	32	12	27.27	87	0	0.00	65	28	30.11
SV2C	0	genome.wustl.edu	37	5	75427805	75427805	+	Missense_Mutation	SNP	A	A	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	5	75427805	75427805	A	G	SNP	SV2C	ENST00000502798	human	ensembl	74_37	+1	known	missense	c.230	p.E77G	1.000	superfamily_MFS_dom_general_subst_transpt,tigrfam_SV2	pfam_MFS,pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_SV2	-	no_errors	SV2C	HGNC	ENSG00000122012	tier1	-	-	32	0	0.00	26	13	33.33	64	0	0.00	56	13	18.84
BCL9	0	genome.wustl.edu	37	1	147096599	147096599	+	Missense_Mutation	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	1	147096599	147096599	C	A	SNP	BCL9	ENST00000234739	human	ensembl	74_37	+1	known	missense	c.4120	p.P1374T	1.000	NULL	pfam_BCL9_beta-catenin-bd_dom	-	no_errors	BCL9	HGNC	ENSG00000116128	tier1	-	-	29	0	0.00	44	5	10.20	29	0	0.00	20	8	28.57
KSR1	0	genome.wustl.edu	37	17	25919582	25919582	+	Missense_Mutation	SNP	A	A	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	25919582	25919582	A	T	SNP	KSR1	ENST00000319524	human	ensembl	74_37	+1	known	missense	c.1229	p.D410V	1.000	NULL	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	KSR1	HGNC	ENSG00000141068	tier1	-	-	73	0	0.00	57	21	26.92	104	0	0.00	86	37	30.08
CENPE	0	genome.wustl.edu	37	4	104061997	104061997	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	4	104061997	104061997	C	T	SNP	CENPE	ENST00000265148	human	ensembl	74_37	-1	known	missense	c.5728	p.E1910K	0.035	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,superfamily_STAT_TF_coiled-coil,superfamily_Signal_recog_particl_SRP54_hlx,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	CENPE	HGNC	ENSG00000138778	tier1	-	-	50	0	0.00	37	34	47.89	117	0	0.00	47	56	54.37
ARHGAP27	0	genome.wustl.edu	37	17	43474374	43474374	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	43474374	43474374	G	C	SNP	ARHGAP27	ENST00000428638	human	ensembl	74_37	-1	known	missense	c.1859	p.P620R	0.000	NULL	pfam_RhoGAP_dom,pfam_WW_dom,pfam_Pleckstrin_homology,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,superfamily_WW_dom,smart_WW_dom,smart_Pleckstrin_homology,smart_RhoGAP_dom,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_WW_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP27	HGNC	ENSG00000159314	tier1	-	-	113	0	0.00	63	23	26.74	21	0	0.00	29	12	29.27
DNMT3B	0	genome.wustl.edu	37	20	31376688	31376688	+	Missense_Mutation	SNP	T	T	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	20	31376688	31376688	T	G	SNP	DNMT3B	ENST00000328111	human	ensembl	74_37	+1	known	missense	c.683	p.L228R	0.999	pfam_PWWP_dom,smart_PWWP_dom,pfscan_PWWP_dom	pfam_PWWP_dom,pfam_C5_MeTfrase,superfamily_Znf_FYVE_PHD,smart_PWWP_dom,pfscan_PWWP_dom	-	no_errors	DNMT3B	HGNC	ENSG00000088305	tier1	-	-	148	0	0.00	178	38	17.59	42	0	0.00	57	17	22.67
KAT2B	0	genome.wustl.edu	37	3	20153214	20153214	+	Silent	SNP	A	A	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	3	20153214	20153214	A	G	SNP	KAT2B	ENST00000263754	human	ensembl	74_37	+1	known	silent	c.978	p.Q326	1.000	pirsf_Hist_acetylase_PCAF,pfam_PCAF_N	pirsf_Hist_acetylase_PCAF,pfam_PCAF_N,pfam_Bromodomain,pfam_GT_dom,superfamily_Bromodomain,superfamily_Acyl_CoA_acyltransferase,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain,pfscan_GT_dom	-	no_errors	KAT2B	HGNC	ENSG00000114166	tier1	-	-	68	0	0.00	76	23	23.23	100	0	0.00	94	24	20.34
TTN	0	genome.wustl.edu	37	2	179440976	179440976	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	179440976	179440976	C	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.62179	p.A20727T	0.948	pfam_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_Fibronectin_type3,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	11	0	0.00	4	4	50.00	104	0	0.00	35	22	38.60
KIF12	0	genome.wustl.edu	37	9	116854198	116854198	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	116854198	116854198	G	C	SNP	KIF12	ENST00000374118	human	ensembl	74_37	-1	known	missense	c.1485	p.S495R	0.931	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF12	HGNC	ENSG00000136883	tier1	-	-	68	0	0.00	54	12	18.18	14	0	0.00	14	5	26.32
ATP10D	0	genome.wustl.edu	37	4	47548647	47548647	+	Missense_Mutation	SNP	G	G	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	4	47548647	47548647	G	A	SNP	ATP10D	ENST00000273859	human	ensembl	74_37	+1	known	missense	c.1403	p.R468K	1.000	superfamily_HAD-like_dom,tigrfam_ATPase_P-typ_Plipid-transp	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP10D	HGNC	ENSG00000145246	tier1	-	-	32	0	0.00	25	9	26.47	79	0	0.00	50	18	26.47
SLC52A3	0	genome.wustl.edu	37	20	746010	746020	+	Frame_Shift_Del	DEL	AGTAGGTGGGC	AGTAGGTGGGC	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	AGTAGGTGGGC	AGTAGGTGGGC	AGTAGGTGGGC	-	AGTAGGTGGGC	AGTAGGTGGGC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	20	746010	746020	AGTAGGTGGGC	-	DEL	SLC52A3	ENST00000217254	human	ensembl	74_37	-1	known	frame_shift_del	c.409_399	p.T135fs	1.000:0.009:0.002:0.001:0.001:0.374:0.000:0.001:0.971:1.000:1.000	NULL	pfam_Endogenous_retrovirus_rcpt	-	no_errors	SLC52A3	HGNC	ENSG00000101276	tier1			32	0	0.00	31	4	11.43	32	0	0.00	31	4	11.43
TTN	0	genome.wustl.edu	37	2	179664458	179664459	+	Frame_Shift_Del	DEL	TC	TC	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	TC	TC	TC	-	TC	TC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	2	179664458	179664459	TC	-	DEL	TTN	ENST00000342992	human	ensembl	74_37	-1	known	frame_shift_del	c.670	p.K224fs	1.000	NULL	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1			32	0	0.00	23	10	30.30	57	0	0.00	23	12	34.29
ZCCHC6	0	genome.wustl.edu	37	9	88967642	88967663	+	Frame_Shift_Del	DEL	TCTTTATGAAACAGTCGTCTTA	TCTTTATGAAACAGTCGTCTTA	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	TCTTTATGAAACAGTCGTCTTA	TCTTTATGAAACAGTCGTCTTA	TCTTTATGAAACAGTCGTCTTA	-	TCTTTATGAAACAGTCGTCTTA	TCTTTATGAAACAGTCGTCTTA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	9	88967642	88967663	TCTTTATGAAACAGTCGTCTTA	-	DEL	ZCCHC6	ENST00000375963	human	ensembl	74_37	-1	known	frame_shift_del	c.473_452	p.V151fs	0.914:0.999:0.999:1.000:1.000:0.999:1.000:1.000:0.995:0.985:0.928:0.467:0.530:0.514:0.411:0.720:0.780:0.976:1.000:1.000:0.985:0.998	NULL	pfam_PAP_assoc,pfam_Znf_CCHC,superfamily_Znf_CCHC,smart_Znf_U1,smart_Znf_CCHC,pfscan_Znf_CCHC	-	no_errors	ZCCHC6	HGNC	ENSG00000083223	tier1			128	0	0.00	108	20	15.62	128	0	0.00	108	20	15.62
LDHB	0	genome.wustl.edu	37	12	21799948	21799956	+	Splice_Site	DEL	AGACTGTAA	AGACTGTAA	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	AGACTGTAA	AGACTGTAA	AGACTGTAA	-	AGACTGTAA	AGACTGTAA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	12	21799948	21799956	AGACTGTAA	-	DEL	LDHB	ENST00000350669	human	ensembl	74_37	-1	known	splice_site_del	c.130-6_130-1	e2-1	1.000:1.000:1.000:1.000:0.991:0.006:0.000:0.001:0.002	-	-	-	no_errors	LDHB	HGNC	ENSG00000111716	tier1			110	0	0.00	77	11	12.50	110	0	0.00	77	11	12.50
SP91	0	genome.wustl.edu	37	6	84311022	84311023	+	Frame_Shift_Ins	INS	-	-	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	6	84311022	84311023	-	T	INS	SP91	ENST00000369694	human	ensembl	74_37	-1	known	frame_shift_ins	c.1292_1291	p.T431fs	1.000:0.998	NULL	pfam_ANTH_dom,pfam_Epsin_dom_N,superfamily_ENTH_VHS,smart_Epsin-like_N,pfscan_Epsin-like_N	-	no_errors	SP91	HGNC	ENSG00000065609	tier1			59	0	0.00	43	34	44.16	104	0	0.00	51	25	32.89
GPX5	0	genome.wustl.edu	37	6	28501767	28501767	+	Frame_Shift_Del	DEL	G	G	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	6	28501767	28501767	G	-	DEL	GPX5	ENST00000412168	human	ensembl	74_37	+1	known	frame_shift_del	c.489	p.G164fs	0.701	superfamily_Thioredoxin-like_fold,pirsf_Glutathione_peroxidase	pfam_Glutathione_peroxidase,superfamily_Thioredoxin-like_fold,pirsf_Glutathione_peroxidase,prints_Glutathione_peroxidase	-	no_errors	GPX5	HGNC	ENSG00000224586	tier1			90	0	0.00	61	79	56.43	117	0	0.00	38	52	57.78
EM	0	genome.wustl.edu	37	4	71509722	71509722	+	Frame_Shift_Del	DEL	A	A	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	4	71509722	71509722	A	-	DEL	EM	ENST00000396073	human	ensembl	74_37	+1	known	frame_shift_del	c.2579	p.E862fs	0.998	NULL	NULL	-	no_errors	EM	HGNC	ENSG00000132464	tier1			12	0	0.00	17	7	29.17	117	0	0.00	89	20	18.35
RPPH1	0	genome.wustl.edu	37	14	20811609	20811609	+	R	DEL	A	A	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	14	20811609	20811609	A	-	DEL	RPPH1	ENST00000554988	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RPPH1	HGNC	ENSG00000259001	tier1			27	0	0.00	8	12	60.00	57	0	0.00	14	37	72.55
GPR123	0	genome.wustl.edu	37	10	134916200	134916200	+	Splice_Site	SNP	G	G	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	134916200	134916200	G	T	SNP	GPR123	ENST00000607359	human	ensembl	74_37	+1	putative	splice_site	c.2416-1	e14-1	1.000	-	-	-	no_errors	GPR123	HGNC	ENSG00000197177	tier1	-	-	113	0	0.00	9	22	68.75	25	0	0.00	2	10	83.33
GRIN3B	0	genome.wustl.edu	37	19	1005248	1005248	+	Missense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	19	1005248	1005248	C	T	SNP	GRIN3B	ENST00000234389	human	ensembl	74_37	+1	known	missense	c.1748	p.A583V	0.994	pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,smart_Iontro_glu_rcpt,prints_NMDA_rcpt	pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIN3B	HGNC	ENSG00000116032	tier1	-	-	139	0	0.00	10	74	87.06	18	0	0.00	1	23	95.83
HPN-AS1	0	genome.wustl.edu	37	19	35597197	35597197	+	R	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	19	35597197	35597197	C	T	SNP	HPN-AS1	ENST00000392227	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.995	-	-	-	no_errors	HPN-AS1	HGNC	ENSG00000227392	tier1	-	-	104	0	0.00	11	40	78.43	18	0	0.00	2	4	66.67
KNDC1	0	genome.wustl.edu	37	10	135024137	135024137	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	135024137	135024137	G	C	SNP	KNDC1	ENST00000368572	human	ensembl	74_37	+1	known	missense	c.3823	p.V1275L	1.000	pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N,pfscan_Ras-like_Gua-exchang_fac_N	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,superfamily_Kinase-like_dom,smart_KIND,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	KNDC1	HGNC	ENSG00000171798	tier1	-	-	127	0	0.00	9	37	80.43	54	1	1.82	6	40	86.96
MGAT5B	0	genome.wustl.edu	37	17	74944891	74944891	+	Nonsense_Mutation	SNP	C	C	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	74944891	74944891	C	T	SNP	MGAT5B	ENST00000428789	human	ensembl	74_37	+1	known	nonsense	c.2377	p.Q793*	1.000	NULL	superfamily_PyrdxlP-dep_Trfase	-	no_errors	MGAT5B	HGNC	ENSG00000167889	tier1	-	-	132	0	0.00	68	70	50.72	7	0	0.00	7	3	30.00
MTTP	0	genome.wustl.edu	37	4	100543870	100543870	+	Silent	SNP	C	C	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	4	100543870	100543870	C	A	SNP	MTTP	ENST00000265517	human	ensembl	74_37	+1	known	silent	c.2550	p.G850	0.981	NULL	pfam_Lipid_transpt_N,superfamily_Vitellinogen_superhlx,superfamily_Lipid_transp_b-sht_shell,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	MTTP	HGNC	ENSG00000138823	tier1	-	-	35	0	0.00	11	25	69.44	54	0	0.00	7	38	84.44
PCDHA1	0	genome.wustl.edu	37	5	140167415	140167415	+	Missense_Mutation	SNP	A	A	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	5	140167415	140167415	A	G	SNP	PCDHA1	ENST00000504120	human	ensembl	74_37	+1	known	missense	c.1540	p.S514G	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA1	HGNC	ENSG00000204970	tier1	-	-	170	0	0.00	66	37	35.92	16	0	0.00	7	2	22.22
PHLPP2	0	genome.wustl.edu	37	16	71712775	71712775	+	Missense_Mutation	SNP	G	G	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	16	71712775	71712775	G	A	SNP	PHLPP2	ENST00000356272	human	ensembl	74_37	-1	known	missense	c.1151	p.P384L	1.000	smart_Leu-rich_rpt_typical-subtyp	pfam_PP2C-like_dom,pfam_Leu-rich_rpt,superfamily_PP2C-like_dom,smart_Leu-rich_rpt_typical-subtyp,smart_PP2C-like_dom	-	no_errors	PHLPP2	HGNC	ENSG00000040199	tier1	-	-	30	0	0.00	3	14	82.35	95	0	0.00	6	36	85.71
SPTBN4	0	genome.wustl.edu	37	19	41019260	41019260	+	Missense_Mutation	SNP	G	G	A			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	19	41019260	41019260	G	A	SNP	SPTBN4	ENST00000352632	human	ensembl	74_37	+1	known	missense	c.2564	p.R855H	1.000	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	-	no_errors	SPTBN4	HGNC	ENSG00000160460	tier1	-	-	45	0	0.00	7	4	33.33	6	0	0.00	0	2	100.00
NEUROG3	0	genome.wustl.edu	37	10	71332468	71332468	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	10	71332468	71332468	G	C	SNP	NEUROG3	ENST00000242462	human	ensembl	74_37	-1	known	missense	c.332	p.P111R	1.000	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	NEUROG3	HGNC	ENSG00000122859	tier1	-	-	86	0	0.00	35	43	55.13	30	1	3.23	9	28	75.68
MIR3938	0	genome.wustl.edu	37	3	55886574	55886574	+	R	DEL	A	A	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	3	55886574	55886574	A	-	DEL	MIR3938	ENST00000582157	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR3938	HGNC	ENSG00000264013	tier1			21	0	0.00	23	13	36.11	39	1	2.50	22	13	37.14
IL17C	0	genome.wustl.edu	37	16	88706424	88706424	+	Frame_Shift_Del	DEL	A	A	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	16	88706424	88706424	A	-	DEL	IL17C	ENST00000244241	human	ensembl	74_37	+1	known	frame_shift_del	c.538	p.T180fs	0.000	pfam_IL-17_fam,prints_IL-17_chr	pfam_IL-17_fam,prints_IL-17_chr	-	no_errors	IL17C	HGNC	ENSG00000124391	tier1			79	0	0.00	16	2	11.11	12	0	0.00	6	0	0.00
TNRC6A	0	genome.wustl.edu	37	16	24788423	24788434	+	In_Frame_Del	DEL	GCAGCCACAGCC	GCAGCCACAGCC	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	GCAGCCACAGCC	GCAGCCACAGCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	16	24788423	24788434	GCAGCCACAGCC	-	DEL	TNRC6A	ENST00000395799	human	ensembl	74_37	+1	known	in_frame_del	c.333_344	p.PQPQ115in_frame_del	0.272:0.260:0.233:0.187:0.163:0.109:0.101:0.113:0.113:0.139:0.129:0.003	NULL	pfam_Argonaute_hook_dom,superfamily_UBA-like	-	no_errors	TNRC6A	HGNC	ENSG00000090905	tier1			5	0	0.00	4	0	0.00	5	0	0.00	4	0	0.00
YY1	0	genome.wustl.edu	37	14	100705951	100705951	+	Nonsense_Mutation	SNP	G	G	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	14	100705951	100705951	G	T	SNP	YY1	ENST00000262238	human	ensembl	74_37	+1	known	nonsense	c.370	p.E124*	1.000	pirsf_TF_Yin_yang	pfam_Znf_C2H2,smart_Znf_C2H2-like,pirsf_TF_Yin_yang,pfscan_Znf_C2H2	-	no_errors	YY1	HGNC	ENSG00000100811	tier1	-	-	49	0	0.00	10	3	23.08	12	0	0.00	9	0	0.00
ENSG00000268673	0	genome.wustl.edu	37	19	15871188	15871188	+	R	SNP	C	C	G			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	19	15871188	15871188	C	G	SNP	ENSG00000268673	ENST00000595525	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	LLNLR-249E10.1	Clone_based_vega_gene	ENSG00000268673	tier1	-	-	127	0	0.00	195	52	21.05	2	0	0.00	1	0	0.00
FAM86HP	0	genome.wustl.edu	37	3	129824474	129824474	+	R	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	3	129824474	129824474	G	C	SNP	FAM86HP	ENST00000500074	human	ensembl	74_37	-1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	FAM86HP	HGNC	ENSG00000253540	tier1	-	-	185	0	0.00	135	50	27.03	0	0	0.00	0	0	0.00
GALNT6	0	genome.wustl.edu	37	12	51785401	51785402	+	R	INS	-	-	AGCCGC			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	12	51785401	51785402	-	AGCCGC	INS	GALNT6	ENST00000603203	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.021:0.127	-	-	-	no_errors	GALNT6	HGNC	ENSG00000139629	tier1			1	0	0.00	0	0	0.00	1	0	0.00	0	0	0.00
GOLGA8M	0	genome.wustl.edu	37	15	28953550	28953550	+	Missense_Mutation	SNP	T	T	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	15	28953550	28953550	T	C	SNP	GOLGA8M	ENST00000563027	human	ensembl	74_37	-1	novel	missense	c.319	p.K107E	0.825	NULL	NULL	-	no_errors	GOLGA8M	HGNC	ENSG00000188626	tier1	-	-	39	0	0.00	36	23	38.98	0	0	0.00	0	0	0.00
HS3ST3B1	0	genome.wustl.edu	37	17	14248744	14248744	+	Missense_Mutation	SNP	G	G	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	17	14248744	14248744	G	T	SNP	HS3ST3B1	ENST00000360954	human	ensembl	74_37	+1	known	missense	c.954	p.K318N	1.000	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST3B1	HGNC	ENSG00000125430	tier1	-	-	23	0	0.00	27	5	15.62	1	0	0.00	3	0	0.00
INSM2	0	genome.wustl.edu	37	14	36004278	36004278	+	Missense_Mutation	SNP	G	G	T			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	14	36004278	36004278	G	T	SNP	INSM2	ENST00000307169	human	ensembl	74_37	+1	known	missense	c.820	p.D274Y	1.000	smart_Znf_C2H2-like	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	INSM2	HGNC	ENSG00000168348	tier1	-	-	89	0	0.00	34	4	10.53	0	0	0.00	2	0	0.00
PLEKHN1	0	genome.wustl.edu	37	1	906235	906235	+	Missense_Mutation	SNP	G	G	C			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	1	906235	906235	G	C	SNP	PLEKHN1	ENST00000379409	human	ensembl	74_37	+1	known	missense	c.581	p.C194S	0.001	smart_Pleckstrin_homology	smart_Pleckstrin_homology	-	no_errors	PLEKHN1	HGNC	ENSG00000187583	tier1	-	-	23	0	0.00	4	5	55.56	1	0	0.00	0	0	0.00
TMEM191C	0	genome.wustl.edu	37	22	21822373	21822385	+	R	DEL	AGGATCCGGGGGT	AGGATCCGGGGGT	-			TCGA-KD-A5QS-01A-11D-A27P-09	TCGA-KD-A5QS-10A-01D-A27P-09	AGGATCCGGGGGT	AGGATCCGGGGGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e341a72a-16fb-4279-b2af-6e2e1e0dafbc	40e2c457-030c-4524-af8a-0da16e6a4b63	22	21822373	21822385	AGGATCCGGGGGT	-	DEL	TMEM191C	ENST00000449424	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.003:0.005:0.001:0.001:0.002:0.003:0.000:0.000:0.000:0.057:0.077:0.000:0.000	-	-	-	no_errors	TMEM191C	HGNC	ENSG00000206140	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00