Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
OR5T2	0	genome.wustl.edu	37	11	56000184	56000184	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	11	56000184	56000184	C	A	SNP	OR5T2	ENST00000313264	human	ensembl	74_37	-1	known	missense	c.478	p.D160Y	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5T2	HGNC	ENSG00000181718	tier1	-	-	64	0	0.00	36	11	23.40	62	0	0.00	18	9	33.33
ZNF282	0	genome.wustl.edu	37	7	148921432	148921432	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	148921432	148921432	G	T	SNP	ZNF282	ENST00000262085	human	ensembl	74_37	+1	known	missense	c.1709	p.G570V	1.000	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,pfam_DUF3669_Znf,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF282	HGNC	ENSG00000170265	tier1	-	-	49	0	0.00	61	12	16.44	25	0	0.00	34	4	10.53
PCDHA11	0	genome.wustl.edu	37	5	140248722	140248722	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	5	140248722	140248722	C	T	SNP	PCDHA11	ENST00000398640	human	ensembl	74_37	+1	known	missense	c.34	p.P12S	0.000	NULL	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA11	HGNC	ENSG00000249158	tier1	-	-	79	0	0.00	90	22	19.64	130	0	0.00	97	31	24.22
MYCBP2	0	genome.wustl.edu	37	13	77798600	77798600	+	Silent	SNP	T	T	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	13	77798600	77798600	T	C	SNP	MYCBP2	ENST00000407578	human	ensembl	74_37	-1	known	silent	c.2925	p.G975	0.999	pfam_Reg_chr_condens,superfamily_RCC1/BLIP-II,superfamily_ARM-type_fold,pfscan_Reg_chr_condens	pfam_PHR,pfam_Reg_chr_condens,pfam_Filamin/ABP280_repeat-like,superfamily_RCC1/BLIP-II,superfamily_Galactose-bd-like,superfamily_Ig_E-set,superfamily_ARM-type_fold,smart_Znf_RING,pfscan_Filamin/ABP280_repeat-like,pfscan_Znf_RING,pfscan_Reg_chr_condens,prints_Reg_chr_condens	-	no_errors	MYCBP2	HGNC	ENSG00000005810	tier1	-	-	57	0	0.00	27	18	40.00	85	0	0.00	40	21	34.43
IGHV1OR21-1	0	genome.wustl.edu	37	21	10862982	10862982	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	21	10862982	10862982	C	A	SNP	IGHV1OR21-1	ENST00000559480	human	ensembl	74_37	+1	known	missense	c.278	p.T93K	0.243	pfam_Ig_V-set,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	IGHV1OR21-1	HGNC	ENSG00000169861	tier1	-	-	185	0	0.00	99	35	26.12	52	0	0.00	19	8	29.63
PAPPA2	0	genome.wustl.edu	37	1	176526055	176526055	+	Silent	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	176526055	176526055	C	A	SNP	PAPPA2	ENST00000367662	human	ensembl	74_37	+1	known	silent	c.597	p.R199	0.001	NULL	pfam_Notch_dom,pfam_Sushi_SCR_CCP,pfam_Peptidase_M43,superfamily_ConA-like_lec_gl_sf,superfamily_Sushi_SCR_CCP,superfamily_Fibronectin_type3,superfamily_Notch_dom,smart_LamG-like,smart_Notch_dom,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP,tigrfam_Myxo_disulph_rpt	-	no_errors	PAPPA2	HGNC	ENSG00000116183	tier1	-	-	39	0	0.00	28	5	15.15	98	0	0.00	75	18	19.35
FAM213B	0	genome.wustl.edu	37	1	2520961	2520961	+	R	SNP	G	G	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	2520961	2520961	G	C	SNP	FAM213B	ENST00000464043	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.015	-	-	-	no_errors	FAM213B	HGNC	ENSG00000157870	tier1	-	-	9	0	0.00	26	8	23.53	74	0	0.00	121	17	12.32
PLEKHG2	0	genome.wustl.edu	37	19	39915497	39915497	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	39915497	39915497	G	T	SNP	PLEKHG2	ENST00000409794	human	ensembl	74_37	+1	known	missense	c.3724	p.G1242C	0.001	NULL	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PLEKHG2	HGNC	ENSG00000090924	tier1	-	-	39	0	0.00	53	12	18.46	108	0	0.00	84	19	18.45
EPHA8	0	genome.wustl.edu	37	1	22903293	22903293	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	22903293	22903293	G	A	SNP	EPHA8	ENST00000166244	human	ensembl	74_37	+1	known	missense	c.743	p.S248N	1.000	pirsf_Tyr_kinase_ephrin_rcpt	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom	-	no_errors	EPHA8	HGNC	ENSG00000070886	tier1	-	-	77	0	0.00	94	9	8.74	29	0	0.00	16	4	20.00
SMIM9	0	genome.wustl.edu	37	X	154057855	154057855	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	X	154057855	154057855	G	T	SNP	SMIM9	ENST00000369529	human	ensembl	74_37	-1	known	missense	c.227	p.A76D	0.002	NULL	NULL	-	no_errors	SMIM9	HGNC	ENSG00000203870	tier1	-	-	41	0	0.00	29	10	25.64	69	0	0.00	30	12	28.57
CCDC27	0	genome.wustl.edu	37	1	3679854	3679854	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	3679854	3679854	C	A	SNP	CCDC27	ENST00000294600	human	ensembl	74_37	+1	known	missense	c.1137	p.D379E	0.000	NULL	superfamily_Prefoldin	-	no_errors	CCDC27	HGNC	ENSG00000162592	tier1	-	-	59	0	0.00	65	10	13.33	79	0	0.00	88	28	24.14
GABRA2	0	genome.wustl.edu	37	4	46305540	46305540	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	4	46305540	46305540	C	T	SNP	GABRA2	ENST00000540012	human	ensembl	74_37	-1	known	missense	c.628	p.V210I	1.000	pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,tigrfam_Neur_channel	pfam_Neurotrans-gated_channel_TM,pfam_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,prints_GABAAa_rcpt,prints_GABAA_rcpt,prints_GABBAa2_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	GABRA2	HGNC	ENSG00000151834	tier1	-	-	77	0	0.00	68	29	29.90	117	0	0.00	86	17	16.50
OR2M3	0	genome.wustl.edu	37	1	248367058	248367058	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	248367058	248367058	C	T	SNP	OR2M3	ENST00000456743	human	ensembl	74_37	+1	known	missense	c.689	p.S230F	0.001	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2M3	HGNC	ENSG00000228198	tier1	-	-	97	0	0.00	84	24	22.22	26	0	0.00	24	7	22.58
ASMT	0	genome.wustl.edu	37	X	1746870	1746870	+	R	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	X	1746870	1746870	G	A	SNP	ASMT	ENST00000509780	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	ASMT	HGNC	ENSG00000196433	tier1	-	-	24	0	0.00	31	25	44.64	107	1	0.93	80	41	33.88
KIAA0947	0	genome.wustl.edu	37	5	5463531	5463531	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	5	5463531	5463531	G	T	SNP	KIAA0947	ENST00000296564	human	ensembl	74_37	+1	known	missense	c.4084	p.D1362Y	0.001	NULL	superfamily_Vitellinogen_superhlx	-	no_errors	KIAA0947	HGNC	ENSG00000164151	tier1	-	-	67	0	0.00	97	13	11.82	71	0	0.00	124	32	20.51
RHPN2	0	genome.wustl.edu	37	19	33498977	33498977	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	33498977	33498977	C	T	SNP	RHPN2	ENST00000254260	human	ensembl	74_37	-1	known	missense	c.703	p.D235N	0.149	pfam_BRO1_dom,pfscan_BRO1_dom	pfam_BRO1_dom,pfam_HR1_rho-bd,superfamily_HR1_rho-bd,superfamily_PDZ,smart_HR1_rho-bd,smart_PDZ,pfscan_BRO1_dom	-	no_errors	RHPN2	HGNC	ENSG00000131941	tier1	-	-	101	0	0.00	133	30	18.40	2	0	0.00	13	3	18.75
CDK13	0	genome.wustl.edu	37	7	40127771	40127771	+	Nonsense_Mutation	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	40127771	40127771	A	T	SNP	CDK13	ENST00000181839	human	ensembl	74_37	+1	known	nonsense	c.3076	p.R1026*	1.000	superfamily_Kinase-like_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK13	HGNC	ENSG00000065883	tier1	-	-	36	0	0.00	16	10	38.46	64	0	0.00	49	25	33.78
DMXL1	0	genome.wustl.edu	37	5	118469962	118469962	+	Splice_Site	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	5	118469962	118469962	G	T	SNP	DMXL1	ENST00000539542	human	ensembl	74_37	+1	known	splice_site	c.2255-1	e13-1	1.000	-	-	-	no_errors	DMXL1	HGNC	ENSG00000172869	tier1	-	-	40	0	0.00	23	14	37.84	61	0	0.00	47	17	26.56
C16orf96	0	genome.wustl.edu	37	16	4626242	4626242	+	Silent	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	16	4626242	4626242	G	A	SNP	C16orf96	ENST00000444310	human	ensembl	74_37	+1	known	silent	c.1761	p.Q587	0.001	NULL	NULL	-	no_errors	C16orf96	HGNC	ENSG00000205832	tier1	-	-	59	0	0.00	66	25	27.47	39	0	0.00	28	6	17.65
PPAP2C	0	genome.wustl.edu	37	19	288083	288083	+	Nonsense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	288083	288083	G	T	SNP	PPAP2C	ENST00000327790	human	ensembl	74_37	-1	known	nonsense	c.204	p.Y68*	0.865	superfamily_P_Acid_Pase_2/haloperoxidase	pfam_P_Acid_Pase_2/haloperoxidase,superfamily_P_Acid_Pase_2/haloperoxidase,smart_P_Acid_Pase_2/haloperoxidase	-	no_errors	PPAP2C	HGNC	ENSG00000141934	tier1	-	-	177	0	0.00	136	37	21.39	109	0	0.00	86	25	22.52
ZNF890P	0	genome.wustl.edu	37	7	5161807	5161807	+	R	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	5161807	5161807	C	T	SNP	ZNF890P	ENST00000422060	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.177	-	-	-	no_errors	ZNF890P	HGNC	ENSG00000159904	tier1	-	-	50	0	0.00	28	9	24.32	63	1	1.56	41	13	24.07
ANKRD30B	0	genome.wustl.edu	37	18	14779966	14779966	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	18	14779966	14779966	G	A	SNP	ANKRD30B	ENST00000358984	human	ensembl	74_37	+1	known	missense	c.1428	p.M476I	0.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ANKRD30B	HGNC	ENSG00000180777	tier1	-	-	100	0	0.00	86	22	20.37	56	0	0.00	30	12	28.57
PCSK9	0	genome.wustl.edu	37	1	55521749	55521749	+	Missense_Mutation	SNP	C	C	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	55521749	55521749	C	G	SNP	PCSK9	ENST00000302118	human	ensembl	74_37	+1	known	missense	c.883	p.R295G	0.996	pfam_Peptidase_S8/S53_dom,superfamily_Peptidase_S8/S53_dom	pfam_Peptidase_S8/S53_dom,pfam_Inhibitor_I9,superfamily_Peptidase_S8/S53_dom,superfamily_Prot_inh_propept,prints_Peptidase_S8_subtilisin-rel	-	no_errors	PCSK9	HGNC	ENSG00000169174	tier1	-	-	51	0	0.00	159	14	8.09	3	0	0.00	23	3	11.54
PCDHA10	0	genome.wustl.edu	37	5	140236983	140236983	+	Silent	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	5	140236983	140236983	C	T	SNP	PCDHA10	ENST00000307360	human	ensembl	74_37	+1	known	silent	c.1350	p.N450	0.906	superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA10	HGNC	ENSG00000250120	tier1	-	-	156	1	0.64	111	86	43.65	39	0	0.00	40	22	35.48
ST6GALC3	0	genome.wustl.edu	37	1	77042702	77042702	+	R	SNP	G	G	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	77042702	77042702	G	C	SNP	ST6GALC3	ENST00000464140	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ST6GALC3	HGNC	ENSG00000184005	tier1	-	-	10	0	0.00	42	14	25.00	156	0	0.00	626	214	25.48
ENSG00000268032	0	genome.wustl.edu	37	19	18142291	18142291	+	R	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	18142291	18142291	C	A	SNP	ENSG00000268032	ENST00000594957	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CTB-52I2.4	Clone_based_vega_gene	ENSG00000268032	tier1	-	-	35	0	0.00	18	8	30.77	45	0	0.00	33	5	13.16
PTH2R	0	genome.wustl.edu	37	2	209358326	209358326	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	209358326	209358326	C	T	SNP	PTH2R	ENST00000272847	human	ensembl	74_37	+1	known	missense	c.1595	p.P532L	0.122	NULL	pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	PTH2R	HGNC	ENSG00000144407	tier1	-	-	28	0	0.00	29	5	14.71	88	0	0.00	50	9	15.25
IQGAP1	0	genome.wustl.edu	37	15	91034675	91034675	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	15	91034675	91034675	A	T	SNP	IQGAP1	ENST00000268182	human	ensembl	74_37	+1	known	missense	c.4359	p.Q1453H	1.000	pfam_RasGAP_C	pfam_RasGAP,pfam_RasGAP_C,pfam_IQ_motif_EF-hand-BS,pfam_CH-domain,pfam_WW_dom,superfamily_Rho_GTPase_activation_prot,superfamily_CH-domain,superfamily_P-loop_NTPase,smart_CH-domain,smart_WW_dom,smart_IQ_motif_EF-hand-BS,smart_RasGAP,pfscan_CH-domain,pfscan_IQ_motif_EF-hand-BS,pfscan_WW_dom,pfscan_RasGAP	-	no_errors	IQGAP1	HGNC	ENSG00000140575	tier1	-	-	65	0	0.00	73	12	14.12	109	0	0.00	125	32	20.38
RYR3	0	genome.wustl.edu	37	15	34028478	34028478	+	Silent	SNP	C	C	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	15	34028478	34028478	C	G	SNP	RYR3	ENST00000389232	human	ensembl	74_37	+1	known	silent	c.7467	p.L2489	0.286	superfamily_ARM-type_fold	pfam_Ryanodine_rcpt,pfam_Ca-rel_channel,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_4_helix_cytokine-like_core,superfamily_ARM-type_fold,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_hand_dom,pfscan_MIR_motif	-	no_errors	RYR3	HGNC	ENSG00000198838	tier1	-	-	89	0	0.00	63	10	13.70	121	0	0.00	48	12	20.00
D2HGDH	0	genome.wustl.edu	37	2	242688377	242688377	+	Silent	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	242688377	242688377	C	T	SNP	D2HGDH	ENST00000537090	human	ensembl	74_37	+1	known	silent	c.951	p.L317	0.017	NULL	pfam_Oxid_FAD_bind_N,superfamily_FAD-bd_2	-	no_errors	D2HGDH	HGNC	ENSG00000180902	tier1	-	-	22	0	0.00	12	19	61.29	29	0	0.00	14	6	30.00
UTP23	0	genome.wustl.edu	37	8	117798782	117798782	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	8	117798782	117798782	G	T	SNP	UTP23	ENST00000357148	human	ensembl	74_37	+1	known	missense	c.404	p.G135V	0.000	NULL	pfam_Fcf1/Utp23	-	no_errors	UTP23	HGNC	ENSG00000147679	tier1	-	-	66	0	0.00	51	11	17.74	77	0	0.00	66	8	10.81
MIR3690	0	genome.wustl.edu	37	X	1412870	1412870	+	R	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	X	1412870	1412870	A	T	SNP	MIR3690	ENST00000580266	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.976	-	-	-	no_errors	MIR3690	HGNC	ENSG00000265658	tier1	-	-	93	0	0.00	84	18	17.65	16	0	0.00	18	3	14.29
ABCB1	0	genome.wustl.edu	37	7	87174310	87174310	+	Silent	SNP	T	T	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	87174310	87174310	T	G	SNP	ABCB1	ENST00000265724	human	ensembl	74_37	-1	known	silent	c.1893	p.A631	0.089	NULL	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,pfam_ABC_ATPase_put,superfamily_P-loop_NTPase,superfamily_ABC1_TM_dom,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom	-	no_errors	ABCB1	HGNC	ENSG00000085563	tier1	-	-	42	0	0.00	31	7	18.42	81	0	0.00	71	14	16.47
CMPK2	0	genome.wustl.edu	37	2	6989960	6989960	+	R	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	6989960	6989960	C	T	SNP	CMPK2	ENST00000478738	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	CMPK2	HGNC	ENSG00000134326	tier1	rs189991705	GMAF=0.0005	52	0	0.00	50	6	10.71	138	0	0.00	113	37	24.50
LPIN2	0	genome.wustl.edu	37	18	2951057	2951057	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	18	2951057	2951057	C	A	SNP	LPIN2	ENST00000261596	human	ensembl	74_37	-1	known	missense	c.586	p.A196S	0.004	NULL	pfam_LNS2,pfam_Lipin_N,superfamily_HAD-like_dom,smart_LNS2	-	no_errors	LPIN2	HGNC	ENSG00000101577	tier1	-	-	34	0	0.00	61	7	10.14	55	0	0.00	88	10	10.20
PCDH9	0	genome.wustl.edu	37	13	66879148	66879148	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	13	66879148	66879148	C	A	SNP	PCDH9	ENST00000377865	human	ensembl	74_37	-1	known	missense	c.3353	p.G1118V	1.000	NULL	pfam_Cadherin,pfam_Protocadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH9	HGNC	ENSG00000184226	tier1	-	-	33	0	0.00	12	4	25.00	91	0	0.00	43	21	32.81
NOS1	0	genome.wustl.edu	37	12	117768198	117768198	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	12	117768198	117768198	C	T	SNP	NOS1	ENST00000317775	human	ensembl	74_37	-1	known	missense	c.677	p.G226E	0.926	pirsf_NOS_euk	pfam_NO_synthase_oxygenase_dom,pfam_FAD-binding_1,pfam_Flavodoxin/NO_synth,pfam_OxRdtase_FAD/D-bd,pfam_PDZ,superfamily_NO_synthase_oxygenase_dom,superfamily_Riboflavin_synthase-like_b-brl,superfamily_PDZ,smart_PDZ,pirsf_NOS_euk,pfscan_PDZ,pfscan_Flavodoxin/NO_synth,prints_Flavoprot_Pyr_Nucl_cyt_Rdtase,prints_Flavdoxin	-	no_errors	NOS1	HGNC	ENSG00000089250	tier1	-	-	32	0	0.00	25	6	19.35	81	0	0.00	66	16	19.51
CDCA3	0	genome.wustl.edu	37	12	6959716	6959716	+	Silent	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	12	6959716	6959716	C	A	SNP	CDCA3	ENST00000538862	human	ensembl	74_37	-1	known	silent	c.165	p.L55	0.002	NULL	NULL	-	no_errors	CDCA3	HGNC	ENSG00000111665	tier1	-	-	60	0	0.00	38	14	26.92	149	0	0.00	83	28	25.23
SCN7A	0	genome.wustl.edu	37	2	167313506	167313506	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	167313506	167313506	C	A	SNP	SCN7A	ENST00000409855	human	ensembl	74_37	-1	known	missense	c.1164	p.L388F	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_Na_trans_assoc,prints_Na_channel_asu	-	no_errors	SCN7A	HGNC	ENSG00000136546	tier1	-	-	69	0	0.00	28	19	40.43	113	1	0.87	40	20	33.33
PTCHD2	0	genome.wustl.edu	37	1	11577619	11577619	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	11577619	11577619	A	T	SNP	PTCHD2	ENST00000294484	human	ensembl	74_37	+1	known	missense	c.1849	p.S617C	0.998	pfam_Patched	pfam_Patched,pfam_MMPL_dom,pfscan_SSD	-	no_errors	PTCHD2	HGNC	ENSG00000204624	tier1	-	-	54	0	0.00	66	19	22.35	23	0	0.00	11	5	31.25
BLNK	0	genome.wustl.edu	37	10	97956691	97956691	+	Silent	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	10	97956691	97956691	G	A	SNP	BLNK	ENST00000224337	human	ensembl	74_37	-1	known	silent	c.1224	p.A408	1.000	pfam_SH2,smart_SH2,pfscan_SH2	pfam_SH2,smart_SH2,pfscan_SH2	-	no_errors	BLNK	HGNC	ENSG00000095585	tier1	-	-	42	0	0.00	31	14	31.11	69	0	0.00	42	18	30.00
GUK1	0	genome.wustl.edu	37	1	228333784	228333784	+	R	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	228333784	228333784	C	T	SNP	GUK1	ENST00000470040	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	GUK1	HGNC	ENSG00000143774	tier1	-	-	63	0	0.00	62	18	22.22	65	0	0.00	25	8	24.24
PDLIM2	0	genome.wustl.edu	37	8	22447119	22447119	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	8	22447119	22447119	G	A	SNP	PDLIM2	ENST00000308354	human	ensembl	74_37	+1	known	missense	c.1378	p.E460K	0.704	NULL	pfam_PDZ,pfam_Znf_LIM,superfamily_PDZ,smart_PDZ,smart_Znf_LIM,pfscan_Znf_LIM,pfscan_PDZ	-	no_errors	PDLIM2	HGNC	ENSG00000120913	tier1	-	-	107	0	0.00	59	33	35.87	29	0	0.00	16	7	30.43
OTOGL	0	genome.wustl.edu	37	12	80770909	80770909	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	12	80770909	80770909	G	A	SNP	OTOGL	ENST00000458043	human	ensembl	74_37	+1	known	missense	c.6761	p.R2254Q	1.000	pfscan_Cys_knot_C	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_AbfB,superfamily_AbfB,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_Cys_knot_C,pfscan_Cys_knot_C	-	no_errors	OTOGL	HGNC	ENSG00000165899	tier1	-	-	154	0	0.00	103	45	30.41	81	0	0.00	79	40	33.61
EPHA6	0	genome.wustl.edu	37	3	97365050	97365050	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	3	97365050	97365050	G	C	SNP	EPHA6	ENST00000514100	human	ensembl	74_37	+1	novel	missense	c.1048	p.G350R	0.015	smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	EPHA6	HGNC	ENSG00000080224	tier1	-	-	79	0	0.00	44	12	21.43	89	0	0.00	40	16	28.57
FOXH1	0	genome.wustl.edu	37	8	145700634	145700634	+	Missense_Mutation	SNP	T	T	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	8	145700634	145700634	T	G	SNP	FOXH1	ENST00000377317	human	ensembl	74_37	-1	known	missense	c.185	p.Q62P	0.999	pfam_TF_fork_head,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head	pfam_TF_fork_head,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head	-	no_errors	FOXH1	HGNC	ENSG00000160973	tier1	-	-	128	0	0.00	137	34	19.77	87	0	0.00	62	14	18.42
INSR	0	genome.wustl.edu	37	19	7267849	7267849	+	Silent	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	7267849	7267849	G	A	SNP	INSR	ENST00000302850	human	ensembl	74_37	-1	known	silent	c.159	p.C53	1.000	pirsf_Tyr_kinase_insulin-like_rcpt,pfam_EGF_rcpt_L	pirsf_Tyr_kinase_insulin-like_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_EGF_rcpt_L,pfam_Prot_kinase_dom,pfam_Furin-like_Cys-rich_dom,pfam_Fibronectin_type3,superfamily_Kinase-like_dom,superfamily_Growth_fac_rcpt_N_dom,superfamily_Fibronectin_type3,smart_Furin_repeat,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom	-	no_errors	INSR	HGNC	ENSG00000171105	tier1	-	-	39	0	0.00	31	16	34.04	94	0	0.00	125	22	14.97
HNF1A	0	genome.wustl.edu	37	12	121434799	121434799	+	Nonstop_Mutation	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	12	121434799	121434799	A	T	SNP	HNF1A	ENST00000543427	human	ensembl	74_37	+1	known	nonstop	c.1212	p.*404C	0.000	NULL	pfam_HNF1b_C,pfam_HNF-1_N,pfam_Homeobox_dom,superfamily_Homeodomain-like,superfamily_Lambda_D-bd_dom,smart_Homeobox_dom,pfscan_Homeobox_dom	-	no_errors	HNF1A	HGNC	ENSG00000135100	tier1	-	-	62	0	0.00	55	16	22.54	152	0	0.00	89	33	26.83
TLDC2	0	genome.wustl.edu	37	20	35506417	35506417	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	20	35506417	35506417	C	T	SNP	TLDC2	ENST00000217320	human	ensembl	74_37	+1	known	missense	c.149	p.T50I	1.000	NULL	pfam_TLDc,smart_TLDc	-	no_errors	TLDC2	HGNC	ENSG00000101342	tier1	-	-	37	0	0.00	40	19	32.20	43	0	0.00	65	31	32.29
RYR1	0	genome.wustl.edu	37	19	39051993	39051993	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	39051993	39051993	C	T	SNP	RYR1	ENST00000359596	human	ensembl	74_37	+1	known	missense	c.12523	p.P4175S	1.000	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_MG_RAP_rcpt_1,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_MIR_motif	-	no_errors	RYR1	HGNC	ENSG00000196218	tier1	-	-	34	0	0.00	38	25	39.68	39	0	0.00	16	10	38.46
MANEA	0	genome.wustl.edu	37	6	96034835	96034835	+	Nonsense_Mutation	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	96034835	96034835	A	T	SNP	MANEA	ENST00000358812	human	ensembl	74_37	+1	known	nonsense	c.520	p.R174*	1.000	superfamily_Glycoside_hydrolase_SF	superfamily_Glycoside_hydrolase_SF	-	no_errors	MANEA	HGNC	ENSG00000172469	tier1	-	-	134	0	0.00	72	24	25.00	60	0	0.00	22	15	40.54
DEFB113	0	genome.wustl.edu	37	6	49936404	49936404	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	49936404	49936404	G	A	SNP	DEFB113	ENST00000398718	human	ensembl	74_37	-1	known	missense	c.235	p.L79F	0.000	NULL	NULL	-	no_errors	DEFB113	HGNC	ENSG00000214642	tier1	-	-	37	0	0.00	47	9	16.07	102	1	0.97	59	19	24.36
DOCK6	0	genome.wustl.edu	37	19	11354301	11354301	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	11354301	11354301	G	A	SNP	DOCK6	ENST00000294618	human	ensembl	74_37	-1	known	missense	c.1190	p.T397M	1.000	NULL	pfam_DOCK_C,pfam_DOCK_C/D_N	-	no_errors	DOCK6	HGNC	ENSG00000130158	tier1	-	-	25	0	0.00	51	11	17.74	19	0	0.00	13	2	13.33
COL1A1	0	genome.wustl.edu	37	17	48271338	48271338	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	17	48271338	48271338	C	A	SNP	COL1A1	ENST00000225964	human	ensembl	74_37	-1	known	missense	c.1733	p.G578V	1.000	NULL	pfam_Collagen,pfam_Fib_collagen_C,pfam_VWF_C,superfamily_Fibrinogen_a/b/g_C_dom,smart_VWF_C,smart_Fib_collagen_C,pfscan_VWF_C	-	no_errors	COL1A1	HGNC	ENSG00000108821	tier1	-	-	49	0	0.00	26	19	42.22	45	0	0.00	20	13	39.39
IL4	0	genome.wustl.edu	37	5	132010060	132010060	+	R	SNP	T	T	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	5	132010060	132010060	T	A	SNP	IL4	ENST00000495905	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.002	-	-	-	no_errors	IL4	HGNC	ENSG00000113520	tier1	-	-	53	0	0.00	47	16	25.40	117	0	0.00	86	15	14.85
MYB	0	genome.wustl.edu	37	6	135521663	135521663	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	135521663	135521663	G	A	SNP	MYB	ENST00000525002	human	ensembl	74_37	+1	known	missense	c.1697	p.R566H	0.000	NULL	pfam_C-myb_C,pfam_SANT/Myb,pfam_Tscrpt_reg_Wos2-domain,superfamily_Homeodomain-like,smart_SANT/Myb,pfscan_Myb-like_dom	-	no_errors	MYB	HGNC	ENSG00000118513	tier1	-	-	22	0	0.00	19	5	20.83	106	0	0.00	52	19	26.76
ATP12A	0	genome.wustl.edu	37	13	25283514	25283514	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	13	25283514	25283514	G	T	SNP	ATP12A	ENST00000218548	human	ensembl	74_37	+1	known	missense	c.2524	p.A842S	1.000	pfam_ATPase_P-typ_cation-transptr_C,tigrfam_ATPase_P-typ_Na/K_IIC	pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_cation-transptr_C,pfam_HAD-like_dom,pfam_ATPase_P-typ_cation-transptr_N,superfamily_ATPase_P-typ_cyto_domN,superfamily_HAD-like_dom,smart_ATPase_P-typ_cation-transptr_N,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Na/K_IIC,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP12A	HGNC	ENSG00000075673	tier1	-	-	132	1	0.75	85	32	27.12	87	0	0.00	36	15	29.41
IGSF5	0	genome.wustl.edu	37	21	41137760	41137760	+	Silent	SNP	T	T	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	21	41137760	41137760	T	C	SNP	IGSF5	ENST00000380588	human	ensembl	74_37	+1	novel	silent	c.399	p.S133	0.004	pfam_Ig_I-set,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_I-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	IGSF5	HGNC	ENSG00000183067	tier1	-	-	36	0	0.00	26	12	31.58	70	0	0.00	36	10	21.74
TANGO6	0	genome.wustl.edu	37	16	68896912	68896912	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	16	68896912	68896912	A	G	SNP	TANGO6	ENST00000261778	human	ensembl	74_37	+1	known	missense	c.800	p.Y267C	1.000	NULL	pfam_DUF2435,pfam_DUF2411,superfamily_ARM-type_fold	-	no_errors	TANGO6	HGNC	ENSG00000103047	tier1	-	-	37	0	0.00	22	28	56.00	102	0	0.00	48	44	47.83
IARS2	0	genome.wustl.edu	37	1	220273947	220273947	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	220273947	220273947	G	T	SNP	IARS2	ENST00000302637	human	ensembl	74_37	+1	known	missense	c.506	p.G169V	0.958	pfam_aa-tR-synth_Ia,pfam_Methionyl/Leucyl_tR_Synth,tigrfam_Ile-tR-ligase	pfam_aa-tR-synth_Ia,pfam_V/L/I-tR-synth_anticodon-bd,pfam_Methionyl/Leucyl_tR_Synth,pfam_Znf_D_glyclase/IsotR_synth,superfamily_tRsynth_1a_anticodon-bd,superfamily_Val/Leu/Ile-tR-synth_edit,prints_Ile-tR-ligase,tigrfam_Ile-tR-ligase	-	no_errors	IARS2	HGNC	ENSG00000067704	tier1	-	-	114	0	0.00	39	58	59.79	106	0	0.00	53	41	43.62
MIR653	0	genome.wustl.edu	37	7	93112121	93112121	+	R	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	93112121	93112121	G	A	SNP	MIR653	ENST00000385279	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	MIR653	HGNC	ENSG00000208014	tier1	-	-	49	0	0.00	44	9	16.98	112	0	0.00	88	33	26.83
CIB4	0	genome.wustl.edu	37	2	26818157	26818157	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	26818157	26818157	C	T	SNP	CIB4	ENST00000288861	human	ensembl	74_37	-1	known	missense	c.215	p.R72K	0.606	NULL	smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	CIB4	HGNC	ENSG00000157884	tier1	-	-	53	0	0.00	46	13	22.03	113	0	0.00	88	21	19.27
DH11	0	genome.wustl.edu	37	7	21784177	21784177	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	21784177	21784177	T	C	SNP	DH11	ENST00000328843	human	ensembl	74_37	+1	known	missense	c.8297	p.F2766S	1.000	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH11	HGNC	ENSG00000105877	tier1	-	-	70	0	0.00	74	12	13.95	103	1	0.95	52	13	20.00
OR5AP2	0	genome.wustl.edu	37	11	56409257	56409257	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	11	56409257	56409257	A	G	SNP	OR5AP2	ENST00000544374	human	ensembl	74_37	-1	known	missense	c.662	p.V221A	0.102	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5AP2	HGNC	ENSG00000172464	tier1	-	-	60	0	0.00	29	10	25.64	88	0	0.00	29	17	36.96
GRID2IP	0	genome.wustl.edu	37	7	6554123	6554123	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	6554123	6554123	G	T	SNP	GRID2IP	ENST00000457091	human	ensembl	74_37	-1	putative	missense	c.1306	p.L436M	1.000	NULL	pfam_FH2_Formin,pfam_PDZ,superfamily_PDZ,smart_PDZ,smart_FH2_Formin,pfscan_PDZ	-	no_errors	GRID2IP	HGNC	ENSG00000215045	tier1	-	-	58	0	0.00	50	10	16.67	84	0	0.00	60	18	23.08
ZNF729	0	genome.wustl.edu	37	19	22498012	22498012	+	Missense_Mutation	SNP	A	A	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	22498012	22498012	A	C	SNP	ZNF729	ENST00000601693	human	ensembl	74_37	+1	novel	missense	c.1793	p.K598T	0.989	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF729	HGNC	ENSG00000196350	tier1	-	-	77	0	0.00	74	17	18.68	36	0	0.00	26	7	21.21
OR2J2	0	genome.wustl.edu	37	6	29141721	29141721	+	Silent	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	29141721	29141721	C	T	SNP	OR2J2	ENST00000377167	human	ensembl	74_37	+1	known	silent	c.309	p.Y103	0.400	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2J2	HGNC	ENSG00000204700	tier1	-	-	73	0	0.00	44	14	24.14	42	0	0.00	19	5	20.83
TRIML2	0	genome.wustl.edu	37	4	189026036	189026036	+	Silent	SNP	A	A	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	4	189026036	189026036	A	T	SNP	TRIML2	ENST00000512729	human	ensembl	74_37	-1	known	silent	c.90	p.A30	0.211	NULL	pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,prints_Butyrophylin	-	no_errors	TRIML2	HGNC	ENSG00000179046	tier1	-	-	60	0	0.00	11	23	67.65	81	0	0.00	29	48	62.34
PPP1R12B	0	genome.wustl.edu	37	1	202385935	202385935	+	Silent	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	202385935	202385935	G	A	SNP	PPP1R12B	ENST00000336894	human	ensembl	74_37	+1	known	silent	c.312	p.L104	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pirsf_Pase-1_reg_su_12A/B/C_euk,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pirsf_Pase-1_reg_su_12A/B/C_euk,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	PPP1R12B	HGNC	ENSG00000077157	tier1	-	-	81	0	0.00	63	17	21.25	66	0	0.00	59	15	20.27
OR1S2	0	genome.wustl.edu	37	11	57971208	57971208	+	Missense_Mutation	SNP	A	A	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	11	57971208	57971208	A	C	SNP	OR1S2	ENST00000302592	human	ensembl	74_37	-1	known	missense	c.446	p.M149R	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR1S2	HGNC	ENSG00000197887	tier1	-	-	89	0	0.00	45	16	26.23	75	1	1.32	55	7	11.29
TP53	0	genome.wustl.edu	37	17	7577551	7577551	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	17	7577551	7577551	C	T	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.730	p.G244S	1.000	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	51	0	0.00	18	67	78.82	91	0	0.00	22	86	78.90
DHRS2	0	genome.wustl.edu	37	14	24113363	24113363	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	14	24113363	24113363	C	A	SNP	DHRS2	ENST00000344777	human	ensembl	74_37	+1	known	missense	c.532	p.P178T	0.004	pfam_DH_sc/Rdtase_SDR,pfam_PKS_KR,prints_ADH_insect	pfam_DH_sc/Rdtase_SDR,pfam_PKS_KR,prints_Glc/ribitol_DH,prints_DHB_DH,prints_DH_sc/Rdtase_SDR,prints_ADH_insect	-	no_errors	DHRS2	HGNC	ENSG00000100867	tier1	-	-	55	0	0.00	38	42	52.50	144	0	0.00	47	78	62.40
TCHHL1	0	genome.wustl.edu	37	1	152058678	152058678	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	152058678	152058678	C	T	SNP	TCHHL1	ENST00000368806	human	ensembl	74_37	-1	known	missense	c.1480	p.G494R	0.002	NULL	pfam_S100_Ca-bd_sub	-	no_errors	TCHHL1	HGNC	ENSG00000182898	tier1	-	-	38	0	0.00	29	25	46.30	119	0	0.00	85	40	32.00
ADAMTSL3	0	genome.wustl.edu	37	15	84611408	84611408	+	Silent	SNP	A	A	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	15	84611408	84611408	A	G	SNP	ADAMTSL3	ENST00000286744	human	ensembl	74_37	+1	known	silent	c.2178	p.R726	0.103	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Thrombospondin_1_rpt,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,smart_Ig_sub,smart_Ig_sub2,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Ig-like_dom,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTSL3	HGNC	ENSG00000156218	tier1	-	-	56	0	0.00	51	10	16.39	61	0	0.00	41	7	14.29
SLC25A25	0	genome.wustl.edu	37	9	130863607	130863607	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	9	130863607	130863607	G	C	SNP	SLC25A25	ENST00000373069	human	ensembl	74_37	+1	known	missense	c.408	p.E136D	1.000	smart_EF_hand_dom,pfscan_EF_hand_dom	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,smart_EF_hand_dom,pfscan_EF_hand_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_carrier,prints_Graves_DC	-	no_errors	SLC25A25	HGNC	ENSG00000148339	tier1	-	-	70	0	0.00	47	22	31.88	42	0	0.00	24	11	31.43
TRPM8	0	genome.wustl.edu	37	2	234894490	234894490	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	234894490	234894490	C	A	SNP	TRPM8	ENST00000324695	human	ensembl	74_37	+1	known	missense	c.2920	p.L974M	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom	-	no_errors	TRPM8	HGNC	ENSG00000144481	tier1	-	-	46	0	0.00	33	11	25.00	106	0	0.00	77	27	25.96
ZBTB7C	0	genome.wustl.edu	37	18	45566623	45566623	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	18	45566623	45566623	T	C	SNP	ZBTB7C	ENST00000332053	human	ensembl	74_37	-1	known	missense	c.856	p.N286D	1.000	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB7C	HGNC	ENSG00000184828	tier1	-	-	49	0	0.00	23	13	35.14	19	0	0.00	13	7	35.00
NOTCH4	0	genome.wustl.edu	37	6	32188548	32188548	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	32188548	32188548	G	C	SNP	NOTCH4	ENST00000375023	human	ensembl	74_37	-1	known	missense	c.907	p.P303A	1.000	pirsf_Notch,pfam_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pirsf_Notch,pfam_EG-like_dom,pfam_Ankyrin_rpt,pfam_EGF-like_Ca-bd_dom,pfam_Notch_dom,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,prints_Notch_4,prints_Notch_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom	-	no_errors	NOTCH4	HGNC	ENSG00000204301	tier1	-	-	78	0	0.00	47	43	47.78	78	0	0.00	41	31	42.47
ATP8A1	0	genome.wustl.edu	37	4	42445682	42445682	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	4	42445682	42445682	T	C	SNP	ATP8A1	ENST00000381668	human	ensembl	74_37	-1	known	missense	c.3023	p.H1008R	1.000	tigrfam_ATPase_P-typ_Plipid-transp	pfam_ATPase_P-typ_transduc_dom_A,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP8A1	HGNC	ENSG00000124406	tier1	-	-	106	0	0.00	108	17	13.60	134	0	0.00	82	28	25.45
ENSG00000245330	0	genome.wustl.edu	37	8	120886034	120886034	+	R	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	8	120886034	120886034	C	T	SNP	ENSG00000245330	ENST00000500705	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.058	-	-	-	no_errors	KB-1471A8.1	Clone_based_vega_gene	ENSG00000245330	tier1	-	-	119	0	0.00	68	64	48.48	34	0	0.00	15	8	34.78
CAC1F	0	genome.wustl.edu	37	X	49067930	49067930	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	X	49067930	49067930	C	A	SNP	CAC1F	ENST00000376265	human	ensembl	74_37	-1	known	missense	c.4145	p.G1382V	1.000	pfam_Ion_trans_dom,pfam_PKD1_2_channel	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,prints_VDCCAlpha1,prints_VDCC_L_a1su	-	no_errors	CAC1F	HGNC	ENSG00000102001	tier1	-	-	32	0	0.00	38	6	13.64	39	0	0.00	54	8	12.90
TGM5	0	genome.wustl.edu	37	15	43552427	43552427	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	15	43552427	43552427	G	T	SNP	TGM5	ENST00000220420	human	ensembl	74_37	-1	known	missense	c.259	p.P87T	0.001	pfam_Transglutaminase_N,superfamily_Ig_E-set	pfam_Transglutaminase_C,pfam_Transglutaminase_N,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like	-	no_errors	TGM5	HGNC	ENSG00000104055	tier1	-	-	40	0	0.00	41	6	12.77	48	0	0.00	25	7	21.88
SH3D19	0	genome.wustl.edu	37	4	152097706	152097706	+	R	SNP	A	A	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	4	152097706	152097706	A	C	SNP	SH3D19	ENST00000604030	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	SH3D19	HGNC	ENSG00000109686	tier1	-	-	46	0	0.00	37	14	27.45	85	0	0.00	79	22	21.78
C3	0	genome.wustl.edu	37	19	6684798	6684798	+	Missense_Mutation	SNP	T	T	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	6684798	6684798	T	A	SNP	C3	ENST00000245907	human	ensembl	74_37	-1	known	missense	c.4017	p.Q1339H	1.000	NULL	pfam_A2M_comp,pfam_A-macroglobulin_rcpt-bd,pfam_Macroglobln_a2,pfam_Netrin_module_non-TIMP,pfam_A2M_N_2,pfam_A2M_N,pfam_MacrogloblnA2_thiol-ester-bond,pfam_Anaphylatoxin/fibulin,superfamily_Terpenoid_cyclase/PrenylTrfase,superfamily_TIMP-like_OB-fold,superfamily_A-macroglobulin_rcpt-bd,superfamily_Anaphylatoxin_comp_syst,smart_Anaphylatoxin/fibulin,smart_Netrin_module_non-TIMP,prints_Anaphylatoxn_comp_syst_dom,pfscan_Anaphylatoxin/fibulin,pfscan_Netrin_domain	-	no_errors	C3	HGNC	ENSG00000125730	tier1	-	-	61	0	0.00	67	7	9.33	130	0	0.00	153	28	15.47
NOTCH4	0	genome.wustl.edu	37	6	32188547	32188547	+	Frame_Shift_Del	DEL	G	G	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	32188547	32188547	G	-	DEL	NOTCH4	ENST00000375023	human	ensembl	74_37	-1	known	frame_shift_del	c.908	p.P303fs	0.983	pirsf_Notch,pfam_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pirsf_Notch,pfam_EG-like_dom,pfam_Ankyrin_rpt,pfam_EGF-like_Ca-bd_dom,pfam_Notch_dom,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,prints_Notch_4,prints_Notch_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom	-	no_errors	NOTCH4	HGNC	ENSG00000204301	tier1			78	0	0.00	45	43	48.86	76	0	0.00	44	29	39.73
NUDT7	0	genome.wustl.edu	37	16	77775652	77775652	+	Frame_Shift_Del	DEL	C	C	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	-	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	16	77775652	77775652	C	-	DEL	NUDT7	ENST00000268533	human	ensembl	74_37	+1	known	frame_shift_del	c.522	p.F175fs	0.625	superfamily_NUDIX_hydrolase_dom-like	pfam_NUDIX_hydrolase_dom,superfamily_NUDIX_hydrolase_dom-like	-	no_errors	NUDT7	HGNC	ENSG00000140876	tier1			72	0	0.00	48	39	44.83	107	0	0.00	49	31	38.75
ATRX	0	genome.wustl.edu	37	X	76889149	76889159	+	Frame_Shift_Del	DEL	TGCTGAAATCC	TGCTGAAATCC	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	TGCTGAAATCC	TGCTGAAATCC	TGCTGAAATCC	-	TGCTGAAATCC	TGCTGAAATCC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	X	76889149	76889159	TGCTGAAATCC	-	DEL	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	frame_shift_del	c.4861_4851	p.D1618fs	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000	pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1			48	0	0.00	15	11	42.31	48	0	0.00	15	11	42.31
MOV10	0	genome.wustl.edu	37	1	113217542	113217542	+	Frame_Shift_Del	DEL	G	G	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	113217542	113217542	G	-	DEL	MOV10	ENST00000357443	human	ensembl	74_37	+1	known	frame_shift_del	c.8	p.S3fs	0.938	NULL	superfamily_P-loop_NTPase	-	no_errors	MOV10	HGNC	ENSG00000155363	tier1			102	0	0.00	50	16	24.24	37	0	0.00	20	3	13.04
DUSP5	0	genome.wustl.edu	37	10	112270097	112270097	+	Frame_Shift_Del	DEL	C	C	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	-	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	10	112270097	112270097	C	-	DEL	DUSP5	ENST00000369583	human	ensembl	74_37	+1	known	frame_shift_del	c.1068	p.P357fs	1.000	pirsf_MKP	pfam_Dual-sp_phosphatase_cat-dom,pfam_Rhodanese-like_dom,pfam_Tyr_Pase_rcpt/non-rcpt,superfamily_Rhodanese-like_dom,smart_Rhodanese-like_dom,smart_Dual-sp_phosphatase_subgr_cat,smart_Tyr_Pase_cat,pirsf_MKP,pfscan_Rhodanese-like_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat,prints_MKP	-	no_errors	DUSP5	HGNC	ENSG00000138166	tier1			27	0	0.00	14	6	30.00	44	0	0.00	14	10	41.67
RBMXL2	0	genome.wustl.edu	37	11	7110702	7110702	+	Silent	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	11	7110702	7110702	C	A	SNP	RBMXL2	ENST00000306904	human	ensembl	74_37	+1	known	silent	c.351	p.G117	0.716	NULL	pfam_RRM_dom,pfam_RBM1CTR,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	RBMXL2	HGNC	ENSG00000170748	tier1	-	-	16	0	0.00	7	5	41.67	14	0	0.00	6	5	45.45
SIGLEC9	0	genome.wustl.edu	37	19	51629011	51629011	+	Silent	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	51629011	51629011	C	A	SNP	SIGLEC9	ENST00000440804	human	ensembl	74_37	+1	known	silent	c.579	p.T193	0.000	pfam_Immunoglobulin,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	SIGLEC9	HGNC	ENSG00000129450	tier1	-	-	56	0	0.00	29	42	56.76	8	0	0.00	5	9	64.29
TBKBP1	0	genome.wustl.edu	37	17	45787898	45787898	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	17	45787898	45787898	G	A	SNP	TBKBP1	ENST00000361722	human	ensembl	74_37	+1	known	missense	c.1754	p.S585N	1.000	NULL	NULL	-	no_errors	TBKBP1	HGNC	ENSG00000198933	tier1	-	-	71	0	0.00	11	41	78.85	53	0	0.00	9	8	47.06
HYAL4	0	genome.wustl.edu	37	7	123516947	123516947	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	123516947	123516947	C	T	SNP	HYAL4	ENST00000223026	human	ensembl	74_37	+1	known	missense	c.1184	p.P395L	0.001	pirsf_Hyaluronidase	pfam_Hyaluronidase,superfamily_Glycoside_hydrolase_SF,pirsf_Hyaluronidase,prints_Hyaluronidase	-	no_errors	HYAL4	HGNC	ENSG00000106302	tier1	rs141828412	GMAF=0.0005	112	0	0.00	122	13	9.56	149	0	0.00	136	11	7.48
TXNRD2	0	genome.wustl.edu	37	22	19907112	19907112	+	Silent	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	22	19907112	19907112	C	A	SNP	TXNRD2	ENST00000535882	human	ensembl	74_37	-1	known	silent	c.180	p.L60	1.000	pfam_Pyr_nucl-diS_OxRdtase_FAD/D,pfam_FAD_bind_dom,pfam_GIDA-rel,prints_FAD_pyr_nucl-diS_OxRdtase,prints_Hg_reductase,tigrfam_Thioredoxin/glutathione_Rdtase	pfam_Pyr_nucl-diS_OxRdtase_FAD/D,pfam_Pyr_nucl-diS_OxRdtase_dimer,pfam_Pyr_OxRdtase_D-bd_dom,pfam_FAD_bind_dom,pfam_GIDA-rel,superfamily_FAD/D-linked_Rdtase_dimer,prints_FAD_pyr_nucl-diS_OxRdtase,prints_Hg_reductase,tigrfam_Thioredoxin/glutathione_Rdtase	-	no_errors	TXNRD2	HGNC	ENSG00000184470	tier1	-	-	89	0	0.00	82	13	13.68	63	0	0.00	64	6	8.45
APOB	0	genome.wustl.edu	37	2	21234165	21234165	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	21234165	21234165	C	A	SNP	APOB	ENST00000233242	human	ensembl	74_37	-1	known	missense	c.5575	p.V1859F	0.001	NULL	pfam_Lipid_transpt_N,pfam_Vitellinogen_open_b-sht,pfam_ApoB100_C,pfam_Lipid_transpt_open_b-sht,superfamily_Lipid_transp_b-sht_shell,superfamily_Vitellinogen_superhlx,superfamily_ARM-type_fold,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	APOB	HGNC	ENSG00000084674	tier1	-	-	57	0	0.00	79	10	11.24	84	1	1.16	74	6	7.50
KIAA0825	0	genome.wustl.edu	37	5	93752974	93752974	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	5	93752974	93752974	G	A	SNP	KIAA0825	ENST00000427991	human	ensembl	74_37	-1	known	missense	c.2594	p.T865I	1.000	NULL	NULL	-	no_errors	KIAA0825	HGNC	ENSG00000185261	tier1	-	-	79	0	0.00	35	5	12.50	156	0	0.00	79	6	6.98
DH11	0	genome.wustl.edu	37	7	21788227	21788227	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	7	21788227	21788227	C	A	SNP	DH11	ENST00000328843	human	ensembl	74_37	+1	known	missense	c.8561	p.P2854H	0.972	superfamily_P-loop_NTPase,smart_AAA+_ATPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH11	HGNC	ENSG00000105877	tier1	-	-	51	0	0.00	36	5	12.20	74	0	0.00	61	5	7.58
SLC47A2	0	genome.wustl.edu	37	17	19611114	19611114	+	Silent	SNP	G	G	A			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	17	19611114	19611114	G	A	SNP	SLC47A2	ENST00000325411	human	ensembl	74_37	-1	known	silent	c.780	p.T260	0.000	tigrfam_MATE	pfam_MATE,tigrfam_MATE	-	no_errors	SLC47A2	HGNC	ENSG00000180638	tier1	-	-	47	0	0.00	114	17	12.98	87	0	0.00	211	16	7.05
LIMCH1	0	genome.wustl.edu	37	4	41607964	41607964	+	Silent	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	4	41607964	41607964	C	T	SNP	LIMCH1	ENST00000313860	human	ensembl	74_37	+1	known	silent	c.429	p.Y143	0.901	superfamily_CH-domain	pfam_CH-domain,pfam_Znf_LIM,superfamily_CH-domain,smart_CH-domain,smart_Znf_LIM,pfscan_CH-domain,pfscan_Znf_LIM,prints_SM22_calponin,prints_Calponin	-	no_errors	LIMCH1	HGNC	ENSG00000064042	tier1	-	-	55	0	0.00	59	10	14.49	138	1	0.71	91	9	9.00
TJAP1	0	genome.wustl.edu	37	6	43470514	43470528	+	R	DEL	AGGAGAGAGGTGGGG	AGGAGAGAGGTGGGG	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	AGGAGAGAGGTGGGG	AGGAGAGAGGTGGGG	AGGAGAGAGGTGGGG	-	AGGAGAGAGGTGGGG	AGGAGAGAGGTGGGG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	6	43470514	43470528	AGGAGAGAGGTGGGG	-	DEL	TJAP1	ENST00000483640	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.010:0.002:0.000:0.000:0.001:0.001:0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.000	-	-	-	no_errors	TJAP1	HGNC	ENSG00000137221	tier1			119	0	0.00	97	9	8.49	119	0	0.00	97	9	8.49
ENSG00000224631	0	genome.wustl.edu	37	16	61089587	61089587	+	R	SNP	T	T	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	16	61089587	61089587	T	G	SNP	ENSG00000224631	ENST00000591758	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-51O6.1	Clone_based_vega_gene	ENSG00000224631	tier1	-	-	32	0	0.00	22	7	23.33	10	0	0.00	5	0	0.00
IVL	0	genome.wustl.edu	37	1	152883319	152883319	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	152883319	152883319	A	G	SNP	IVL	ENST00000368764	human	ensembl	74_37	+1	known	missense	c.1046	p.Q349R	0.063	pfam_Involucrin_rpt	pfam_Involucrin_N,pfam_Involucrin_rpt	-	no_errors	IVL	HGNC	ENSG00000163207	tier1	-	-	89	0	0.00	82	9	9.89	11	0	0.00	5	0	0.00
RBMX	0	genome.wustl.edu	37	X	135961586	135961588	+	Frame_Shift_Del	DEL	TGT	TGT	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	TGT	TGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	X	135961586	135961588	TGT	-	DEL	RBMX	ENST00000320676	human	ensembl	74_37	-1	known	frame_shift_del	c.1	p.M1fs	1.000	NULL	pfam_RRM_dom,pfam_RBM1CTR,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	RBMX	HGNC	ENSG00000147274	tier1			17	0	0.00	15	2	11.76	8	0	0.00	6	0	0.00
SIGLEC16	0	genome.wustl.edu	37	19	50472930	50472930	+	R	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	50472930	50472930	C	T	SNP	SIGLEC16	ENST00000602139	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	SIGLEC16	HGNC	ENSG00000161643	tier1	-	-	27	0	0.00	23	4	14.81	7	0	0.00	2	0	0.00
ENSG00000230615	0	genome.wustl.edu	37	1	44569970	44569971	+	R	INS	-	-	GCTTCTCCTGGCCCAGAGTCTCCAGCTGCCGCC			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	44569970	44569971	-	GCTTCTCCTGGCCCAGAGTCTCCAGCTGCCGCC	INS	ENSG00000230615	ENST00000434244	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000:0.999	-	-	-	no_errors	RP5-1198O20.4	Clone_based_vega_gene	ENSG00000230615	tier1			3	0	0.00	0	0	0.00	3	0	0.00	0	0	0.00
ENSG00000232274	0	genome.wustl.edu	37	1	143196624	143196624	+	R	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	143196624	143196624	C	T	SNP	ENSG00000232274	ENST00000412204	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.024	-	-	-	no_errors	RP11-782C8.2	Clone_based_vega_gene	ENSG00000232274	tier1	-	-	76	0	0.00	51	24	32.00	1	0	0.00	1	0	0.00
EOMES	0	genome.wustl.edu	37	3	27763427	27763428	+	In_Frame_Ins	INS	-	-	CGGCGC			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	3	27763427	27763428	-	CGGCGC	INS	EOMES	ENST00000449599	human	ensembl	74_37	-1	known	in_frame_ins	c.359_358	p.120in_frame_insGA	0.116:0.075	NULL	pfam_TF_T-box,superfamily_p53-like_TF_D-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box	-	no_errors	EOMES	HGNC	ENSG00000163508	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
NUMBL	0	genome.wustl.edu	37	19	41173893	41173898	+	In_Frame_Del	DEL	TGCTGT	TGCTGT	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	TGCTGT	TGCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	19	41173893	41173898	TGCTGT	-	DEL	NUMBL	ENST00000252891	human	ensembl	74_37	-1	known	in_frame_del	c.1310_1305	p.QQ439in_frame_del	1.000:1.000:1.000:1.000:1.000:0.998	pirsf_Numb/numb-like	pfam_Numb_domain,pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pirsf_Numb/numb-like,pfscan_PTB/PI_dom	-	no_errors	NUMBL	HGNC	ENSG00000105245	tier1			1	0	0.00	3	0	0.00	1	0	0.00	3	0	0.00
SPEG	0	genome.wustl.edu	37	2	220330645	220330646	+	R	DEL	GC	GC	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	GC	GC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	2	220330645	220330646	GC	-	DEL	SPEG	ENST00000462545	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.015:0.006	-	-	-	no_errors	SPEG	HGNC	ENSG00000072195	tier1			8	0	0.00	17	4	19.05	0	0	0.00	0	0	0.00
LY9	0	genome.wustl.edu	37	1	160771614	160771614	+	Silent	SNP	C	C	T			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	1	160771614	160771614	C	T	SNP	LY9	ENST00000368039	human	ensembl	74_37	+1	known	silent	c.489	p.I163	0.999	NULL	pfam_Ig_V-set,smart_Ig_sub	-	no_errors	LY9	HGNC	ENSG00000122224	tier1	-	-	90	0	0.00	64	18	21.95	0	0	0.00	4	2	33.33
RPH3A	0	genome.wustl.edu	37	12	113307826	113307826	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	12	113307826	113307826	T	C	SNP	RPH3A	ENST00000389385	human	ensembl	74_37	+1	known	missense	c.778	p.S260P	0.997	NULL	pfam_C2_dom,pfam_Znf_FYVE-typ,superfamily_C2_dom,superfamily_Znf_FYVE_PHD,smart_C2_dom,pfscan_C2_dom,pfscan_Znf_FYVE-typ,pfscan_Znf_FYVE-rel,prints_Synaptotagmin,prints_C2_dom	-	no_errors	RPH3A	HGNC	ENSG00000089169	tier1	-	-	34	0	0.00	36	12	25.00	36	0	0.00	33	3	8.33
INVS	0	genome.wustl.edu	37	9	103055210	103055249	+	Frame_Shift_Del	DEL	ATTGACCTTCTCCCCGTAGAGCTCCGACTGCAGATAATTC	ATTGACCTTCTCCCCGTAGAGCTCCGACTGCAGATAATTC	-			TCGA-X6-A7WC-01A-12D-A351-09	TCGA-X6-A7WC-10A-01D-A351-09	ATTGACCTTCTCCCCGTAGAGCTCCGACTGCAGATAATTC	ATTGACCTTCTCCCCGTAGAGCTCCGACTGCAGATAATTC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	efa39e31-447e-403d-bdc4-5109d85fbfdd	f4e49b2c-3b30-4f98-b01d-8c69a8da817a	9	103055210	103055249	ATTGACCTTCTCCCCGTAGAGCTCCGACTGCAGATAATTC	-	DEL	INVS	ENST00000262457	human	ensembl	74_37	+1	known	frame_shift_del	c.2671_2710	p.I891fs	1.000:1.000:0.995:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.995:0.746:0.872:0.907:0.908:0.996:1.000:1.000:0.999:0.991:0.976:0.991:0.985:0.643:0.990:0.996:0.994:0.995:0.994:1.000:1.000:1.000:0.995:1.000:1.000:1.000:1.000	NULL	pfam_Ankyrin_rpt,pfam_IQ_motif_EF-hand-BS,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,smart_Ankyrin_rpt,smart_IQ_motif_EF-hand-BS,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_IQ_motif_EF-hand-BS,prints_Ankyrin_rpt	-	no_errors	INVS	HGNC	ENSG00000119509	tier1			95	0	0.00	60	2	3.23	95	0	0.00	60	2	3.23