Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HIST1H1E	3008	broad.mit.edu	37	6	26156924	26156924	+	Silent	SNP	G	G	T			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr6:26156924G>T	ENST00000304218.3	+	1	366	c.306G>T	c.(304-306)tcG>tcT	p.S102S		NM_005321.2	NP_005312.1	P10412	H14_HUMAN	histone cluster 1, H1e	102	H15.				nucleosome assembly	nucleosome|nucleus	DNA binding|protein binding			NS(2)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(1)|liver(1)|lung(9)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)	26						CCGGCGCGTCGGGTTCCTTCA	0.612000													3	70					0.150653	0.159023	1	1	0
MUC4	4585	broad.mit.edu	37	3	195511945	195511945	+	Missense_Mutation	SNP	G	G	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr3:195511945G>A	ENST00000463781.3	-	2	6965	c.6506C>T	c.(6505-6507)gCa>gTa	p.A2169V	MUC4_ENST00000346145.4_Intron|MUC4_ENST00000475231.1_Missense_Mutation_p.A2169V|MUC4_ENST00000349607.4_Intron	NM_018406.6	NP_060876.5	Q99102	MUC4_HUMAN	mucin 4, cell surface associated	948					cell-matrix adhesion	integral to plasma membrane|proteinaceous extracellular matrix	ErbB-2 class receptor binding|extracellular matrix constituent, lubricant activity	p.A2169V(4)		NS(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(5)|lung(23)|ovary(3)|prostate(8)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	51	all_cancers(143;1.11e-08)|Ovarian(172;0.0634)|Breast(254;0.206)	Lung NSC(153;0.191)	Epithelial(36;3.72e-24)|all cancers(36;6.22e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.1e-18)|Lung(62;4.65e-05)|LUSC - Lung squamous cell carcinoma(58;5.31e-05)	GBM - Glioblastoma multiforme(46;2.37e-05)		ACCTGTGGATGCTGAGGAAGT	0.572000													3	12					0	0	1	0	0
TAOK2	9344	broad.mit.edu	37	16	29998500	29998500	+	Silent	SNP	G	G	C			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr16:29998500G>C	ENST00000308893.4	+	16	3950	c.2907G>C	c.(2905-2907)ctG>ctC	p.L969L	TAOK2_ENST00000543033.1_Silent_p.L856L|TAOK2_ENST00000279394.3_Intron|TAOK2_ENST00000416441.2_Silent_p.L796L	NM_001252043.1|NM_016151.3	NP_001238972.1|NP_057235.2	Q9UL54	TAOK2_HUMAN	TAO kinase 2	969	Leu-rich.				actin cytoskeleton organization|activation of MAPKK activity|apoptosis|cell migration|focal adhesion assembly|positive regulation of JNK cascade|protein targeting to membrane|regulation of cell growth|regulation of cell shape|response to stress	cytoplasmic vesicle membrane|cytoskeleton|dendrite|integral to membrane|nucleolus	ATP binding|protein serine/threonine kinase activity			breast(1)|endometrium(3)|large_intestine(5)|lung(8)|ovary(1)|prostate(3)|skin(1)	22						TGCCCCTCCTGCTGCTGCTGC	0.711000													3	88					0	0	1	0	0
MYH10	4628	broad.mit.edu	37	17	8397110	8397110	+	Missense_Mutation	SNP	C	C	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr17:8397110C>G	ENST00000360416.3	-	32	4288	c.4150G>C	c.(4150-4152)Gag>Cag	p.E1384Q	MYH10_ENST00000396239.1_Missense_Mutation_p.E1374Q|MYH10_ENST00000269243.4_Missense_Mutation_p.E1353Q|MYH10_ENST00000379980.4_Missense_Mutation_p.E1369Q	NM_001256012.1	NP_001242941.1	P35580	MYH10_HUMAN	myosin, heavy chain 10, non-muscle	1353					actin filament-based movement|axon guidance|cytokinesis after mitosis|regulation of cell shape	cell cortex|cleavage furrow|midbody|myosin complex|stress fiber	actin filament binding|actin-dependent ATPase activity|ADP binding|ATP binding|calmodulin binding|microfilament motor activity			breast(5)|endometrium(9)|kidney(2)|large_intestine(16)|lung(9)|ovary(3)|prostate(3)|skin(4)|stomach(1)	52						TCCTCCTCCTCCTGCTGCTCC	0.587000													3	71					0	0	1	0	0
LOC101927209	101927209	broad.mit.edu	37	1	142713773	142713773	+	RNA	SNP	C	C	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr1:142713773C>G	ENST00000369381.2	-	0	832																											TCTTTTTCCACATTGTCATTT	0.284000													3	59					0	0	1	0	0
CYP2D7	1564	broad.mit.edu	37	22	42538870	42538870	+	RNA	SNP	A	A	C	rs2982057	by1000genomes	TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr22:42538870A>C	ENST00000433992.1	-	0	475				CYP2D7P1_ENST00000424775.1_RNA|CYP2D7P1_ENST00000358097.4_RNA																endometrium(1)	1						CCATAGCGCGACAGGAACACC	0.687000													3	52					0	0	1	0	0
GGT3P	2679	broad.mit.edu	37	22	18778601	18778601	+	RNA	SNP	C	C	T			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr22:18778601C>T	ENST00000412448.1	-	0	804																											GCTTGGCATCCGCGGCCACGG	0.627000													6	12					0	0	1	0	0
ZNF708	7562	broad.mit.edu	37	19	21476519	21476519	+	Missense_Mutation	SNP	T	T	C			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr19:21476519T>C	ENST00000356929.3	-	4	1446	c.1249A>G	c.(1249-1251)Aag>Gag	p.K417E		NM_021269.2	NP_067092.2	P17019	ZN708_HUMAN	zinc finger protein 708	417					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|central_nervous_system(6)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(9)|ovary(2)|skin(2)|stomach(1)	32						TAGGGTTTCTTTCCAGTATGA	0.343000													3	57					0	0	1	0	0
TSPAN4	7106	broad.mit.edu	37	11	864455	864455	+	Missense_Mutation	SNP	C	C	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr11:864455C>G	ENST00000397404.1	+	5	533	c.274C>G	c.(274-276)Ctg>Gtg	p.L92V	TSPAN4_ENST00000397408.1_Missense_Mutation_p.L92V|TSPAN4_ENST00000397396.1_Missense_Mutation_p.L28V|TSPAN4_ENST00000397406.1_Missense_Mutation_p.L92V|TSPAN4_ENST00000346501.4_Missense_Mutation_p.L92V|TSPAN4_ENST00000409543.2_Missense_Mutation_p.L92V|TSPAN4_ENST00000525201.1_Missense_Mutation_p.L28V|TSPAN4_ENST00000409531.1_Missense_Mutation_p.L111V|TSPAN4_ENST00000397411.2_Missense_Mutation_p.L92V|TSPAN4_ENST00000397397.2_Missense_Mutation_p.L92V	NM_001025237.1	NP_001020408.1	O14817	TSN4_HUMAN	tetraspanin 4	92					protein complex assembly	integral to plasma membrane				breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)	3		all_cancers(49;2.64e-08)|all_epithelial(84;4.17e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.191)|all_lung(207;0.24)		all cancers(45;4.32e-25)|Epithelial(43;3.29e-24)|BRCA - Breast invasive adenocarcinoma(625;4.23e-05)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)		GCTGCTGCTGCTGGTGTTCCT	0.672000													4	175					0	0	1	0	0
MUC20	200958	broad.mit.edu	37	3	195453332	195453332	+	Missense_Mutation	SNP	G	G	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr3:195453332G>A	ENST00000320736.6	+	3	1471	c.1345G>A	c.(1345-1347)Ggg>Agg	p.G449R	MUC20_ENST00000445522.2_Missense_Mutation_p.G585R|MUC20_ENST00000447234.2_Missense_Mutation_p.G620R|MUC20_ENST00000436408.1_Missense_Mutation_p.G620R	NM_001098516.1|NM_152673.2	NP_001091986.1|NP_689886.2	Q8N307	MUC20_HUMAN	mucin 20, cell surface associated	620					protein homooligomerization	apical plasma membrane|basal plasma membrane|extracellular region|microvillus membrane				NS(1)|breast(1)|endometrium(3)|kidney(3)|large_intestine(3)|lung(4)|skin(4)|stomach(3)|upper_aerodigestive_tract(1)	23	all_cancers(143;1.8e-08)|Ovarian(172;0.0634)	Lung NSC(153;0.191)	Epithelial(36;1e-21)|all cancers(36;9.02e-20)|OV - Ovarian serous cystadenocarcinoma(49;1.6e-18)|Lung(62;0.000104)|LUSC - Lung squamous cell carcinoma(58;0.000128)	GBM - Glioblastoma multiforme(46;1.66e-05)		CAGCAGCCGAGGGACGAACAG	0.612000													4	177					0	0	1	0	0
ZNF462	58499	broad.mit.edu	37	9	109701290	109701290	+	Missense_Mutation	SNP	T	T	C			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr9:109701290T>C	ENST00000277225.5	+	7	6618	c.6329T>C	c.(6328-6330)cTg>cCg	p.L2110P	ZNF462_ENST00000441147.2_Missense_Mutation_p.L1016P|ZNF462_ENST00000542028.1_Missense_Mutation_p.L67P|ZNF462_ENST00000457913.1_Missense_Mutation_p.L2170P			Q96JM2	ZN462_HUMAN	zinc finger protein 462	2110					transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(2)|autonomic_ganglia(2)|breast(5)|central_nervous_system(4)|cervix(1)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(17)|large_intestine(20)|lung(32)|ovary(5)|prostate(6)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	119						GGAAAAGCCCTGACCCTCCCC	0.557000													6	340					0	0	1	0	0
TOR1AIP2	163590	broad.mit.edu	37	1	179815714	179815714	+	Missense_Mutation	SNP	C	C	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr1:179815714C>A	ENST00000367612.3	-	6	1292	c.905G>T	c.(904-906)cGg>cTg	p.R302L		NM_001199260.1|NM_145034.4	NP_001186189.1|NP_659471.1	Q8NFQ8	TOIP2_HUMAN	torsin A interacting protein 2	302						endoplasmic reticulum membrane|integral to membrane	protein binding	p.R302L(1)		cervix(1)|endometrium(3)|large_intestine(1)|lung(10)|ovary(1)|skin(2)	18						TCTTCCCTCCCGAGCTGCTGT	0.542000													4	141					1	1	1	1	0
LOC101927209	101927209	broad.mit.edu	37	1	142713774	142713774	+	RNA	SNP	A	A	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr1:142713774A>G	ENST00000369381.2	-	0	831																											CTTTTTCCACATTGTCATTTT	0.284000													3	59					0	0	1	0	0
CLASP2	23122	broad.mit.edu	37	3	33602361	33602361	+	Frame_Shift_Del	DEL	T	T	-			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr3:33602361delT	ENST00000399362.4	-	28	3243	c.2890delA	c.(2890-2892)tgfs	p.M964fs	CLASP2_ENST00000480013.1_Frame_Shift_Del_p.M744fs|CLASP2_ENST00000468888.2_Frame_Shift_Del_p.M965fs|CLASP2_ENST00000307312.7_Frame_Shift_Del_p.M446fs|CLASP2_ENST00000539981.1_Frame_Shift_Del_p.M734fs|CLASP2_ENST00000461133.3_Frame_Shift_Del_p.M724fs|CLASP2_ENST00000359576.5_Frame_Shift_Del_p.M956fs	NM_015097.2	NP_055912.2	B2RTR1	B2RTR1_HUMAN	cytoplasmic linker associated protein 2	966										breast(2)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(19)|ovary(3)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	48						TCAGCACCCATTTTTTTTAGT	0.343													8	163	---	---	---	---					
HTT	3064	broad.mit.edu	37	4	3076604	3076609	+	In_Frame_Del	DEL	CAGCAG	CAGCAG	-	rs71180116		TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr4:3076604_3076609delCAGCAG	ENST00000355072.5	+	1	197_202	c.52_57delCAGCAG	c.(52-57)del	p.QQ36del		NM_002111.6	NP_002102.4	P42858	HD_HUMAN	huntingtin	36	Poly-Gln.				establishment of mitotic spindle orientation|Golgi organization|retrograde vesicle-mediated transport, Golgi to ER|vesicle transport along microtubule	autophagic vacuole|axon|cytoplasmic vesicle membrane|cytosol|dendrite|endoplasmic reticulum|Golgi apparatus|late endosome|membrane fraction|nucleus|protein complex	beta-tubulin binding|dynactin binding|dynein intermediate chain binding|p53 binding|transcription factor binding			breast(1)|cervix(2)|endometrium(14)|kidney(5)|large_intestine(23)|lung(28)|ovary(4)|prostate(2)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	87		all_epithelial(65;0.18)		UCEC - Uterine corpus endometrioid carcinoma (64;0.187)		CAAGTCCTTCcagcagcagcagcagc	0.704													3	4	---	---	---	---					
LOC153910	153910	broad.mit.edu	37	6	142860298	142860299	+	RNA	INS	-	-	T	rs143051118	by1000genomes	TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr6:142860298_142860299insT	ENST00000447311.1	-	0	364					NR_027312.1																						ttaggccagtatttttttttta	0.470													4	2	---	---	---	---					
RP11-519G16.3	0	broad.mit.edu	37	15	45756124	45756128	+	RNA	DEL	CTCCA	CTCCA	-	rs71700299		TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr15:45756124_45756128delCTCCA	ENST00000560077.1	+	0	41				RP11-519G16.3_ENST00000558536.1_RNA|RP11-519G16.3_ENST00000560647.1_RNA																							ccatcaccatctccacaccatcacc	0.551													2	4	---	---	---	---					
LINC00162	378825	broad.mit.edu	37	21	46422090	46422091	+	RNA	INS	-	-	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr21:46422090_46422091insA	ENST00000422199.1	-	0	284					NR_024089.1																						gggggttggggaagggtggggc	0.703													2	4	---	---	---	---