Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
SPTSSA	171546	broad.mit.edu	37	14	34931373	34931373	+	Missense_Mutation	SNP	G	G	C			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr14:34931373G>C	uc001wsc.3	-	0	96	c.41C>G	c.(40-42)tCc>tGc	p.S14C		NM_138288	NP_612145	Q969W0	SSPTA_HUMAN	Homo sapiens serine palmitoyltransferase, small subunit A (SPTSSA), mRNA.	14					sphingolipid biosynthetic process	integral to membrane|serine C-palmitoyltransferase complex	protein binding										GTAGAACCAGGACATCTGCTT	0.697000													4	16					0	0	1	0	0
DYNC1I1	1780	broad.mit.edu	37	7	95442507	95442507	+	Splice_Site	SNP	G	G	A			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr7:95442507G>A	uc003uoc.4	+	4	501	c.224_splice	c.e4-1	p.V75_splice	DYNC1I1_uc003uod.4_Intron|DYNC1I1_uc003uob.3_Intron|DYNC1I1_uc003uoe.4_Splice_Site_p.V75_splice|DYNC1I1_uc010lfl.3_Intron	NM_004411	NP_004402	O14576	DC1I1_HUMAN	Homo sapiens dynein, cytoplasmic 1, intermediate chain 1 (DYNC1I1), transcript variant 1, mRNA.	75	Interaction with DCTN1 (By similarity).				vesicle transport along microtubule	condensed chromosome kinetochore|cytoplasmic dynein complex|microtubule|perinuclear region of cytoplasm|spindle pole|vesicle	microtubule binding|microtubule motor activity			NS(2)|autonomic_ganglia(1)|breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(10)|lung(27)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	54	all_cancers(62;9.39e-10)|all_epithelial(64;2.28e-09)|Lung NSC(181;0.165)|all_lung(186;0.191)		STAD - Stomach adenocarcinoma(171;0.0957)			CTCTTCACCAGTGCAGCCGCT	0.413000													36	76					0	0	1	0	0
WNK4	65266	broad.mit.edu	37	17	40948252	40948253	+	Missense_Mutation	DNP	GC	GC	AG			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr17:40948252_40948253GC>AG	uc002ibj.3	+	16	3611_3612	c.3543_3544GC>AG	c.(3541-3546)atgctg>atAGtg	p.1181_1182ML>IV	WNK4_uc010wgx.2_Missense_Mutation_p.845_846ML>IV|CCDC56_uc010wgz.1_Intron|CNTD1_uc002ibm.4_5'Flank|CNTD1_uc010wha.2_5'Flank	NM_032387	NP_115763	Q96J92	WNK4_HUMAN	Homo sapiens WNK lysine deficient protein kinase 4 (WNK4), mRNA.	1181					intracellular protein kinase cascade	tight junction	ATP binding|protein serine/threonine kinase activity			NS(1)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(10)|ovary(3)|prostate(1)|skin(5)|stomach(1)	35		Breast(137;0.000143)		BRCA - Breast invasive adenocarcinoma(366;0.0749)		CAGCTGCTATGCTGTCCAGCCG	0.609000													7	17					0	0	1	0	0
METRNL	284207	broad.mit.edu	37	17	81042863	81042863	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr17:81042863C>T	uc002kgh.3	+	1	345	c.220C>T	c.(220-222)Cgc>Tgc	p.R74C	METRNL_uc002kgi.3_5'UTR	NM_001004431	NP_001004431	Q641Q3	METRL_HUMAN	Homo sapiens meteorin, glial cell differentiation regulator-like (METRNL), mRNA.	74						extracellular region				endometrium(1)|kidney(1)|large_intestine(1)|lung(3)|skin(1)|upper_aerodigestive_tract(1)	8	Breast(20;0.000443)|all_neural(118;0.0779)		BRCA - Breast invasive adenocarcinoma(99;0.0517)|OV - Ovarian serous cystadenocarcinoma(97;0.0868)			GGTGTATCTGCGCTGTGCGGC	0.652000													5	62					0	0	1	0	0
ATR	545	broad.mit.edu	37	3	142278216	142278216	+	Silent	SNP	A	A	G			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr3:142278216A>G	uc003eux.4	-	6	1731	c.1609T>C	c.(1609-1611)Ttg>Ctg	p.L537L		NM_001184	NP_001175	Q13535	ATR_HUMAN	Homo sapiens ataxia telangiectasia and Rad3 related (ATR), mRNA.	537					DNA damage checkpoint|DNA repair|DNA replication|cell cycle|cellular response to UV|cellular response to gamma radiation|multicellular organismal development|negative regulation of DNA replication|peptidyl-serine phosphorylation|positive regulation of DNA damage response, signal transduction by p53 class mediator|protein autophosphorylation|replicative senescence	PML body	ATP binding|DNA binding|MutLalpha complex binding|MutSalpha complex binding|protein serine/threonine kinase activity			NS(1)|breast(10)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(20)|liver(2)|lung(45)|ovary(3)|skin(10)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(4)	122						TAAAAATCCAATGACATCCAA	0.363000								Other conserved DNA damage response genes					20	34					0	0	1	0	0
C15orf39	56905	broad.mit.edu	37	15	75501019	75501019	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr15:75501019C>T	uc002azp.4	+	1	2950	c.2630C>T	c.(2629-2631)aCg>aTg	p.T877M	C15orf39_uc002azq.4_Missense_Mutation_p.T877M|C15orf39_uc021sqm.1_Missense_Mutation_p.T636M|C15orf39_uc002azr.4_Missense_Mutation_p.T275M	NM_015492	NP_056307	Q6ZRI6	CO039_HUMAN	Homo sapiens chromosome 15 open reading frame 39 (C15orf39), mRNA.	877										autonomic_ganglia(1)|breast(2)|endometrium(3)|large_intestine(4)|lung(4)|skin(1)|upper_aerodigestive_tract(1)	16						CGGCCCACCACGCTGTCGGAG	0.667000													4	15					0	0	1	0	0
TRIP12	9320	broad.mit.edu	37	2	230664036	230664036	+	Nonsense_Mutation	SNP	G	G	T			TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr2:230664036G>T	uc002vpx.1	-	21	3298	c.3189C>A	c.(3187-3189)taC>taA	p.Y1063*	TRIP12_uc021vxw.1_Nonsense_Mutation_p.Y1048*|TRIP12_uc002vpy.1_Nonsense_Mutation_p.Y745*|TRIP12_uc002vpw.1_Nonsense_Mutation_p.Y1015*|TRIP12_uc010zlz.1_Non-coding_Transcript	NM_004238	NP_004229	Q14669	TRIPC_HUMAN	Homo sapiens thyroid hormone receptor interactor 12 (TRIP12), mRNA.	1015					protein ubiquitination involved in ubiquitin-dependent protein catabolic process	proteasome complex	thyroid hormone receptor binding|ubiquitin-protein ligase activity	p.Y1015*(1)		breast(2)|central_nervous_system(4)|cervix(1)|endometrium(5)|kidney(6)|large_intestine(19)|lung(32)|ovary(5)|prostate(4)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	87		Renal(207;0.025)|all_hematologic(139;0.122)|all_lung(227;0.126)|Acute lymphoblastic leukemia(138;0.164)		Epithelial(121;4.76e-13)|all cancers(144;4.34e-10)|LUSC - Lung squamous cell carcinoma(224;0.00864)|Lung(119;0.0116)		TTGGAGGTGAGTACTTTGGCC	0.428000													18	77					0	0	1	0	0
CD209	30835	broad.mit.edu	37	19	7810588	7810588	+	Missense_Mutation	SNP	C	C	G	rs112592254		TCGA-DJ-A2Q1-01A-22D-A19J-08	TCGA-DJ-A2Q1-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	007aab66-2f07-459d-8952-3041d6ea24a8	ae3bdd94-c5b3-4d12-9b54-00ad13bdd3a2	g.chr19:7810588C>G	uc002mht.2	-	3	631	c.564G>C	c.(562-564)aaG>aaC	p.K188N	CD209_uc010xju.1_Intron|CD209_uc010dvp.2_Missense_Mutation_p.K164N|CD209_uc002mhr.2_Missense_Mutation_p.K164N|CD209_uc002mhs.2_Missense_Mutation_p.K164N|CD209_uc002mhu.2_Intron|CD209_uc010dvq.2_Missense_Mutation_p.K188N|CD209_uc002mhq.2_Missense_Mutation_p.K188N|CD209_uc002mhv.2_Missense_Mutation_p.K164N|CD209_uc002mhx.2_Missense_Mutation_p.K144N|CD209_uc002mhw.2_Intron|CD209_uc010dvr.2_Intron	NM_021155	NP_066978	Q9NNX6	CD209_HUMAN	Homo sapiens CD209 molecule (CD209), transcript variant 1, mRNA.	188	7 X approximate tandem repeats.				cell-cell recognition|endocytosis|heterophilic cell-cell adhesion|innate immune response|intracellular signal transduction|intracellular virion transport|leukocyte cell-cell adhesion|peptide antigen transport|viral genome replication|virion attachment to host cell surface receptor	cytoplasm|extracellular region|integral to membrane|plasma membrane	mannose binding|metal ion binding|peptide antigen binding|receptor activity|virion binding			endometrium(7)|kidney(3)|large_intestine(6)|lung(10)|ovary(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	35						TCTCCTGCTGCTTAGATTTCT	0.557000													13	130					0	0	1	0	0