Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KIF23	9493	broad.mit.edu	37	15	69708349	69708349	+	Missense_Mutation	SNP	C	C	T			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr15:69708349C>T	uc002asb.3	+	1	206	c.28C>T	c.(28-30)Cgg>Tgg	p.R10W	KIF23_uc002asc.3_Missense_Mutation_p.R10W|KIF23_uc010bii.3_5'UTR|KIF23_uc010bih.2_Non-coding_Transcript	NM_138555	NP_612565	Q02241	KIF23_HUMAN	Homo sapiens kinesin family member 23 (KIF23), transcript variant 1, mRNA.	10	Kinesin-motor.				blood coagulation|cytokinesis|microtubule-based movement|mitosis|mitotic spindle elongation	cytosol|kinesin complex|microtubule|midbody|nucleoplasm|spindle	ATP binding|microtubule motor activity|protein binding			central_nervous_system(1)|endometrium(4)|large_intestine(7)|lung(6)|prostate(2)|skin(1)	21						TAAGACACCCCGGAAACCTAC	0.363000													3	16					0	0	1	0	0
GPKOW	27238	broad.mit.edu	37	X	48974115	48974115	+	Missense_Mutation	SNP	C	C	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chrX:48974115C>A	uc004dmr.3	-	4	623	c.616G>T	c.(616-618)Ggt>Tgt	p.G206C		NM_015698	NP_056513	Q92917	GPKOW_HUMAN	Homo sapiens G patch domain and KOW motifs (GPKOW), mRNA.	206	G-patch.					nucleus	nucleic acid binding			breast(1)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(1)|lung(11)|ovary(2)	21						AGGTTGGCACCCAGCCCTAAC	0.572000													3	12					0	0	1	0	0
SYCP2L	221711	broad.mit.edu	37	6	10894210	10894210	+	Missense_Mutation	SNP	A	A	T			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr6:10894210A>T	uc003mzo.3	+	2	485	c.189A>T	c.(187-189)ttA>ttT	p.L63F	SYCP2L_uc011dim.1_Non-coding_Transcript	NM_001040274	NP_001035364	Q5T4T6	SYC2L_HUMAN	Homo sapiens synaptonemal complex protein 2-like (SYCP2L), mRNA.	63						nucleus				breast(3)|central_nervous_system(1)|kidney(4)|large_intestine(10)|lung(12)|ovary(1)|skin(3)|stomach(1)|urinary_tract(1)	36	Breast(50;0.0838)|Ovarian(93;0.107)	all_hematologic(90;0.135)	Epithelial(50;0.239)			GTCTTCTATTATACCGTCTTG	0.294000													7	24					0	0	1	0	0
ZNF207	7756	broad.mit.edu	37	17	30687676	30687676	+	Missense_Mutation	SNP	G	G	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr17:30687676G>A	uc010csz.3	+	4	723	c.376G>A	c.(376-378)Gcc>Acc	p.A126T	ZNF207_uc002hhj.4_Missense_Mutation_p.A123T|ZNF207_uc002hhh.4_Missense_Mutation_p.A123T|ZNF207_uc002hhi.4_Missense_Mutation_p.A123T|ZNF207_uc002hhk.1_Missense_Mutation_p.A123T|ZNF207_uc002hhl.1_Non-coding_Transcript			O43670	ZN207_HUMAN	Homo sapiens zinc finger protein 207 (ZNF207), transcript variant 3, mRNA.	123						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|endometrium(2)|kidney(2)|lung(3)|urinary_tract(2)	10		Breast(31;0.116)|Ovarian(249;0.182)	BRCA - Breast invasive adenocarcinoma(9;0.239)			CGACTCTGCAGCCTCAACTTC	0.398000													3	32					0	0	1	0	0
IL17RC	84818	broad.mit.edu	37	3	9965966	9965966	+	Silent	SNP	C	C	T			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr3:9965966C>T	uc003bua.3	+	8	1244	c.1026C>T	c.(1024-1026)ctC>ctT	p.L342L	CIDEC_uc003bto.3_Intron|IL17RC_uc010hcr.3_Non-coding_Transcript|IL17RC_uc011ato.2_Non-coding_Transcript|IL17RC_uc010hcs.3_Silent_p.L246L|IL17RC_uc003btz.3_Silent_p.L271L|IL17RC_uc011atp.2_Silent_p.L127L|IL17RC_uc003bud.3_5'UTR|IL17RC_uc010hct.3_Silent_p.L271L|IL17RC_uc010hcu.3_Silent_p.L271L|IL17RC_uc003bub.3_Silent_p.L256L|IL17RC_uc010hcv.3_Silent_p.L256L|IL17RC_uc003buc.3_5'UTR|IL17RC_uc011atq.2_Silent_p.L256L	NM_153461	NP_703191	Q8NAC3	I17RC_HUMAN	Homo sapiens interleukin 17 receptor C (IL17RC), transcript variant 2, mRNA.	342						integral to membrane|plasma membrane	receptor activity			breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(3)|lung(3)|ovary(3)|pancreas(1)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	22						TTCCCTGCCTCTGTATTCAGG	0.507000													3	17					0	0	1	0	0
ABCC2	1244	broad.mit.edu	37	10	101558994	101558994	+	Missense_Mutation	SNP	G	G	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr10:101558994G>A	uc001kqf.2	+	7	1037	c.898G>A	c.(898-900)Ggg>Agg	p.G300R		NM_000392	NP_000383	Q92887	MRP2_HUMAN	Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2), mRNA.	300						apical plasma membrane|integral to plasma membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances|organic anion transmembrane transporter activity			NS(1)|breast(5)|endometrium(9)|kidney(2)|large_intestine(20)|liver(1)|lung(20)|ovary(2)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	67		Colorectal(252;0.234)		Epithelial(162;2.77e-10)|all cancers(201;2.47e-08)	Adenosine triphosphate(DB00171)|Norgestimate(DB00957)|Pravastatin(DB00175)|Saquinavir(DB01232)|Sulfinpyrazone(DB01138)	AAAGAAGTCTGGGACCAAAAA	0.418000													22	165					0	0	1	0	0
CIT	11113	broad.mit.edu	37	12	120263094	120263094	+	Missense_Mutation	SNP	C	C	T			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr12:120263094C>T	uc001txj.2	-	7	888	c.832G>A	c.(832-834)Ggc>Agc	p.G278S	CIT_uc001txi.2_Missense_Mutation_p.G278S	NM_001206999	NP_001193928	O14578	CTRO_HUMAN	Homo sapiens citron (rho-interacting, serine/threonine kinase 21) (CIT), transcript variant 1, mRNA.	278	Protein kinase.				intracellular signal transduction		ATP binding|SH3 domain binding|metal ion binding|protein serine/threonine kinase activity|small GTPase regulator activity			breast(6)|endometrium(9)|kidney(4)|large_intestine(15)|liver(1)|lung(29)|ovary(7)|prostate(4)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(6)	86	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)	Myeloproliferative disorder(1001;0.0255)		BRCA - Breast invasive adenocarcinoma(302;0.211)		CCGTAGGTGCCTTTTCCATCC	0.527000													6	74					0	0	1	0	0
SLC35D2	11046	broad.mit.edu	37	9	99113432	99113432	+	Silent	SNP	G	G	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr9:99113432G>A	uc004awc.3	-	5	517	c.441C>T	c.(439-441)atC>atT	p.I147I	SLC35D2_uc010msd.3_Non-coding_Transcript|SLC35D2_uc010msf.3_Silent_p.I147I	NM_007001	NP_008932	Q76EJ3	S35D2_HUMAN	Homo sapiens solute carrier family 35, member D2 (SLC35D2), mRNA.	147						Golgi membrane|integral to membrane	nucleotide-sugar transmembrane transporter activity			endometrium(3)|large_intestine(3)|lung(4)|skin(2)	12		Acute lymphoblastic leukemia(62;0.0167)				CACTGAGGATGATGTTGAGTG	0.353000													14	23					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr7:140453136A>T	uc003vwc.4	-	14	1860	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333	NP_004324	P15056	BRAF_HUMAN	Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA.	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(41204)|p.V600K(615)|p.V600?(377)|p.V600R(99)|p.V600D(40)|p.V600_K601>E(30)|p.V600L(28)|p.V600A(24)|p.V600G(22)|p.V600M(22)|p.A598_T599insV(7)|p.T599_V600insT(7)|p.T599I(5)|p.V600Q(4)|p.T599_R603>I(4)|p.T599_V600insTT(3)|p.T599_V600insDFGLAT(2)|p.T599_V600>IAL(2)|p.V600_S605>EK(2)|p.T599T(2)|p.V600_S605>DV(2)|p.V600_S605>D(2)|p.V600_W604del(1)|p.V600V(1)|p.T599_V600insV(1)|p.V600>DLAT(1)|p.D594_T599del(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				17	44					0	0	1	0	0
RIOK1	83732	broad.mit.edu	37	6	7393347	7393347	+	Missense_Mutation	SNP	G	G	C			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr6:7393347G>C	uc003mxn.3	+	1	261	c.87G>C	c.(85-87)ttG>ttC	p.L29F	RIOK1_uc003mxm.1_5'UTR	NM_031480	NP_694550	Q9BRS2	RIOK1_HUMAN	Homo sapiens RIO kinase 1 (yeast) (RIOK1), transcript variant 1, mRNA.	29							ATP binding|protein serine/threonine kinase activity	p.L22F(1)		cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(6)|ovary(2)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	19	Ovarian(93;0.0418)					ACAGAGACTTGAAGACAGTCA	0.333000													4	46					0	0	1	0	0
DRAM1	55332	broad.mit.edu	37	12	102314992	102314992	+	Splice_Site	SNP	A	A	G			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr12:102314992A>G	uc001tix.3	+	7	1136	c.673_splice	c.e7-2	p.S225_splice	DRAM1_uc010svv.2_Splice_Site_p.S115_splice	NM_018370	NP_060840	Q8N682	DRAM1_HUMAN	Homo sapiens DNA-damage regulated autophagy modulator 1 (DRAM1), mRNA.	225					apoptosis|autophagy	integral to membrane|lysosomal membrane				central_nervous_system(1)|endometrium(2)|large_intestine(3)|lung(3)|ovary(1)|prostate(1)|skin(1)	12						TTTTAAAAATAGAGTGTCACC	0.373000													6	87					0	0	1	0	0
IL16	3603	broad.mit.edu	37	15	81592023	81592023	+	Missense_Mutation	SNP	G	G	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr15:81592023G>A	uc010unp.2	+	13	2508	c.2482G>A	c.(2482-2484)Gct>Act	p.A828T	IL16_uc010blq.1_Missense_Mutation_p.A740T|IL16_uc002bge.4_Non-coding_Transcript|IL16_uc002bgg.3_Missense_Mutation_p.A786T|IL16_uc021ssh.1_Missense_Mutation_p.A786T|IL16_uc002bgi.1_Missense_Mutation_p.A176T|IL16_uc002bgj.3_Missense_Mutation_p.A280T|IL16_uc021ssi.1_Missense_Mutation_p.A85T|IL16_uc002bgl.1_Missense_Mutation_p.A85T|IL16_uc010unq.1_Missense_Mutation_p.A85T	NM_172217	NP_001165599	Q14005	IL16_HUMAN	Homo sapiens interleukin 16 (IL16), transcript variant 2, mRNA.	786					immune response|interspecies interaction between organisms|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|extracellular space|nucleus|plasma membrane	cytokine activity			NS(1)|autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(5)|large_intestine(12)|lung(20)|ovary(3)|skin(3)|stomach(1)|urinary_tract(1)	57						TCCTCCTGTGGCTCCCAAGCC	0.572000													11	49					0	0	1	0	0
ABCC8	6833	broad.mit.edu	37	11	17432134	17432134	+	Silent	SNP	G	G	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr11:17432134G>A	uc001mnc.3	-	21	2749	c.2623C>T	c.(2623-2625)Ctg>Ttg	p.L875L		NM_000352	NP_000343	Q09428	ABCC8_HUMAN	Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (ABCC8), mRNA.	875	ABC transporter 1.				carbohydrate metabolic process|energy reserve metabolic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances|potassium ion transmembrane transporter activity|sulfonylurea receptor activity			NS(1)|breast(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(14)|lung(38)|ovary(1)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	67				READ - Rectum adenocarcinoma(2;0.0325)|Colorectal(2;0.1)	Adenosine triphosphate(DB00171)|Glibenclamide(DB01016)|Gliclazide(DB01120)|Mitiglinide(DB01252)|Nateglinide(DB00731)|Repaglinide(DB00912)	TCCCGGAGCAGCTCAAGGATG	0.562000													6	83					0	0	1	0	0
SNX2	6643	broad.mit.edu	37	5	122131017	122131017	+	Missense_Mutation	SNP	C	C	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr5:122131017C>A	uc003kte.3	+	1	214	c.165C>A	c.(163-165)aaC>aaA	p.N55K	SNX2_uc011cwn.2_5'UTR	NM_003100	NP_003091	O60749	SNX2_HUMAN	Homo sapiens sorting nexin 2 (SNX2), mRNA.	55					cell communication|endocytosis|intracellular protein transport	early endosome membrane	phosphatidylinositol binding|protein binding|protein transporter activity			NS(1)|breast(1)|endometrium(4)|kidney(3)|large_intestine(6)|lung(2)|prostate(1)|skin(1)	19		all_cancers(142;1.14e-44)|all_lung(232;1.03e-13)|Lung NSC(810;2.5e-13)|Breast(839;0.000812)|Myeloproliferative disorder(839;0.0122)|Prostate(80;0.0235)|all_hematologic(541;0.0592)|all_neural(839;0.243)	KIRC - Kidney renal clear cell carcinoma(527;0.0897)|Kidney(363;0.137)	all cancers(49;2.13e-24)|Epithelial(69;6.15e-22)|OV - Ovarian serous cystadenocarcinoma(64;5.6e-11)|BRCA - Breast invasive adenocarcinoma(61;0.00013)|GBM - Glioblastoma multiforme(465;0.000357)|COAD - Colon adenocarcinoma(49;0.000887)|Lung(113;0.0109)		TTAGTGCAAACTCCAATGGCC	0.353000													4	85					0	0	1	0	0
RAD54L2	23132	broad.mit.edu	37	3	51664942	51664942	+	Missense_Mutation	SNP	C	C	A			TCGA-EL-A3CM-01A-11D-A19J-08	TCGA-EL-A3CM-10A-01D-A19M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d34d5a0d-21e2-4dfd-9ea6-a5e432ea6450	5a04fb3c-932a-4d0e-8f09-456a60b6739d	g.chr3:51664942C>A	uc011bdt.2	+	5	945	c.820C>A	c.(820-822)Cat>Aat	p.H274N	RAD54L2_uc003dbh.3_5'UTR|RAD54L2_uc011bdu.2_5'UTR|RAD54L2_uc003dbj.3_5'UTR	NM_015106	NP_055921	Q9Y4B4	ARIP4_HUMAN	Homo sapiens RAD54-like 2 (S. cerevisiae) (RAD54L2), mRNA.	274						nucleus	ATP binding|DNA binding|helicase activity			NS(2)|breast(1)|cervix(2)|endometrium(4)|large_intestine(5)|liver(2)|lung(9)|ovary(4)|skin(2)	31				BRCA - Breast invasive adenocarcinoma(193;0.000102)|Kidney(197;0.000758)|KIRC - Kidney renal clear cell carcinoma(197;0.000896)		TGTGAAACCTCATCAGGTACA	0.512000													10	26					0	0	1	0	0