Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut CDHR1 92211 broad.mit.edu 37 10 85972907 85972907 + Missense_Mutation SNP G G C rs144856473 TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr10:85972907G>C uc001kcv.3 + 15 1948 c.1843G>C c.(1843-1845)Gag>Cag p.E615Q CDHR1_uc001kcw.3_Missense_Mutation_p.E615Q|CDHR1_uc009xst.3_Missense_Mutation_p.E319Q|CDHR1_uc001kcx.3_5'UTR NM_033100 NP_149091 Q96JP9 CDHR1_HUMAN Homo sapiens cadherin-related family member 1 (CDHR1), transcript variant 1, mRNA. 615 Cadherin 6. homophilic cell adhesion calcium ion binding|receptor activity p.E615K(2) breast(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(6)|liver(1)|lung(21)|ovary(1)|prostate(1)|skin(1) 36 CACCCATGCAGAGCCCGCCAA 0.572000 7 128 0 0 1 0 0 OR10G2 26534 broad.mit.edu 37 14 22102364 22102364 + Missense_Mutation SNP G G A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr14:22102364G>A uc010tmc.2 - 0 635 c.635C>T c.(634-636)gCc>gTc p.A212V NM_001005466 NP_001005466 Q8NGC3 O10G2_HUMAN Homo sapiens olfactory receptor, family 10, subfamily G, member 2 (OR10G2), mRNA. 212 sensory perception of smell integral to membrane|plasma membrane olfactory receptor activity cervix(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(12)|prostate(1)|skin(2)|stomach(2) 22 all_cancers(95;0.00113) Acute lymphoblastic leukemia(2;0.0279) GBM - Glioblastoma multiforme(265;0.0142) GCAACTGGCGGCCACTACCCT 0.532000 3 112 0 0 1 0 0 FAM117B 150864 broad.mit.edu 37 2 203590986 203590986 + Missense_Mutation SNP G G T TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr2:203590986G>T uc010zhx.2 + 3 870 c.860G>T c.(859-861)cGc>cTc p.R287L NM_173511 NP_775782 Q6P1L5 F117B_HUMAN Homo sapiens family with sequence similarity 117, member B (FAM117B), mRNA. 287 p.K286*(1) breast(3)|central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(4)|lung(5)|ovary(1) 17 GCAAAATTACGCCAGCAGTTG 0.393000 4 95 0 0 1 0 0 QSER1 79832 broad.mit.edu 37 11 32956671 32956671 + Silent SNP G G A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr11:32956671G>A uc001mty.3 + 3 3747 c.3480G>A c.(3478-3480)ggG>ggA p.G1160G QSER1_uc001mtz.1_Silent_p.G921G|QSER1_uc001mua.3_Silent_p.G665G NM_001076786 NP_001070254 Q2KHR3 QSER1_HUMAN Homo sapiens glutamine and serine rich 1 (QSER1), mRNA. 1160 breast(5)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(16)|ovary(4)|prostate(1)|skin(5)|stomach(1)|urinary_tract(1) 48 Breast(20;0.158) TGAAATCCGGGCCCAAGCAGC 0.448000 3 64 0 0 1 0 0 FECH 2235 broad.mit.edu 37 18 55247321 55247321 + Missense_Mutation SNP C C T TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr18:55247321C>T uc002lgp.4 - 1 295 c.178G>A c.(178-180)Gtt>Att p.V60I FECH_uc002lgq.4_Missense_Mutation_p.V60I|FECH_uc002lgr.4_5'UTR NM_001012515 NP_001012533 P22830 HEMH_HUMAN Homo sapiens ferrochelatase (FECH), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. 60 generation of precursor metabolites and energy|heme biosynthetic process|protoporphyrinogen IX metabolic process|response to light stimulus mitochondrial inner membrane|mitochondrial matrix 2 iron, 2 sulfur cluster binding|ferrochelatase activity|ferrous iron binding|protein binding central_nervous_system(1)|endometrium(2)|kidney(2)|large_intestine(3)|lung(5)|prostate(1)|upper_aerodigestive_tract(1) 15 Colorectal(73;0.227) TGCGGTTGAACTTGAGGTTTT 0.522000 9 142 0 0 1 0 0 BRAF 673 broad.mit.edu 37 7 140453136 140453136 + Missense_Mutation SNP A A T rs121913377 TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr7:140453136A>T uc003vwc.4 - 14 1860 c.1799T>A c.(1798-1800)gTg>gAg p.V600E NM_004333 NP_004324 P15056 BRAF_HUMAN Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA. 600 Protein kinase. V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis). activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission cytosol|nucleus|plasma membrane ATP binding|metal ion binding p.V600E(41204)|p.V600K(615)|p.V600?(377)|p.V600R(99)|p.V600D(40)|p.V600_K601>E(30)|p.V600L(28)|p.V600A(24)|p.V600G(22)|p.V600M(22)|p.A598_T599insV(7)|p.T599_V600insT(7)|p.T599I(5)|p.V600Q(4)|p.T599_R603>I(4)|p.T599_V600insTT(3)|p.T599_V600insDFGLAT(2)|p.T599_V600>IAL(2)|p.V600_S605>EK(2)|p.T599T(2)|p.V600_S605>DV(2)|p.V600_S605>D(2)|p.V600_W604del(1)|p.V600V(1)|p.T599_V600insV(1)|p.V600>DLAT(1)|p.D594_T599del(1) SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2) NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3) 27380 Melanoma(164;0.00956) Sorafenib(DB00398) TCGAGATTTCACTGTAGCTAG 0.368000 V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN) 61 """Mis, T, O""" """AKAP9, KIAA1549""" """melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma""" Cardio-facio-cutaneous syndrome Cardiofaciocutaneous syndrome 31 48 0 0 1 0 0 RBM28 55131 broad.mit.edu 37 7 127963614 127963614 + Missense_Mutation SNP C C T TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr7:127963614C>T uc003vmp.2 - 12 1485 c.1370G>A c.(1369-1371)gGt>gAt p.G457D RBM28_uc011koj.1_Missense_Mutation_p.G316D NM_018077 NP_060547 Q9NW13 RBM28_HUMAN Homo sapiens RNA binding motif protein 28 (RBM28), transcript variant 1, mRNA. 457 RNA splicing|mRNA processing Golgi apparatus|nucleolus|spliceosomal complex RNA binding|nucleotide binding breast(1)|kidney(7)|large_intestine(3)|lung(8)|ovary(2) 21 AGCACTCACACCCTCTGCAGC 0.458000 6 140 0 0 1 0 0 AGPS 8540 broad.mit.edu 37 2 178307134 178307134 + Splice_Site SNP G G A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr2:178307134G>A uc002ull.2 + 7 757 c.710_splice c.e7-1 p.G237_splice AGPS_uc010zfb.1_Splice_Site_p.G147_splice NM_003659 NP_003650 O00116 ADAS_HUMAN Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA. 237 FAD-binding PCMH-type. ether lipid biosynthetic process peroxisomal matrix|peroxisomal membrane|plasma membrane alkylglycerone-phosphate synthase activity|flavin adenine dinucleotide binding|oxidoreductase activity breast(2)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(8)|lung(12)|ovary(2)|skin(1) 32 OV - Ovarian serous cystadenocarcinoma(117;0.0018)|Epithelial(96;0.00919)|all cancers(119;0.0358) TATTTTGGCAGGAGGAACAAG 0.333000 3 87 0 0 1 0 0 MARS 4141 broad.mit.edu 37 12 57892382 57892382 + Missense_Mutation SNP G G A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr12:57892382G>A uc001sog.3 + 8 1221 c.1067G>A c.(1066-1068)cGc>cAc p.R356H MARS_uc001sof.1_Non-coding_Transcript|MARS_uc010srp.1_Missense_Mutation_p.R229H|MARS_uc010srq.1_Missense_Mutation_p.R122H NM_004990 NP_004981 P56192 SYMC_HUMAN Homo sapiens methionyl-tRNA synthetase (MARS), mRNA. 356 methionyl-tRNA aminoacylation cytosol ATP binding|methionine-tRNA ligase activity|protein binding|tRNA binding breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(8)|lung(8)|ovary(3)|pancreas(1)|prostate(2)|skin(1) 33 GBM - Glioblastoma multiforme(3;4.27e-41) L-Methionine(DB00134) ATTTTTGGTCGCACCACCACT 0.498000 3 100 0 0 1 0 0 ATP6V1C1 528 broad.mit.edu 37 8 104066176 104066176 + Missense_Mutation SNP G G A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr8:104066176G>A uc003ykz.4 + 6 783 c.538G>A c.(538-540)Gag>Aag p.E180K ATP6V1C1_uc010mbz.3_Missense_Mutation_p.E105K|ATP6V1C1_uc003yla.3_Missense_Mutation_p.E180K|ATP6V1C1_uc011lhl.2_Missense_Mutation_p.E105K NM_001695 NP_001686 P21283 VATC1_HUMAN Homo sapiens ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 (ATP6V1C1), mRNA. 180 ATP hydrolysis coupled proton transport|cellular iron ion homeostasis|insulin receptor signaling pathway|transferrin transport cytosol|plasma membrane|proton-transporting V-type ATPase, V1 domain protein binding|proton-transporting ATPase activity, rotational mechanism breast(1)|endometrium(1)|kidney(2)|large_intestine(2)|lung(6)|urinary_tract(1) 13 Lung NSC(17;0.000427)|all_lung(17;0.000533) OV - Ovarian serous cystadenocarcinoma(57;3.57e-05)|STAD - Stomach adenocarcinoma(118;0.133) TCTTGATTCAGAGTATCTCGT 0.308000 7 82 0 0 1 0 0 TDP1 55775 broad.mit.edu 37 14 90430003 90430003 + Missense_Mutation SNP C C A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr14:90430003C>A uc001xxy.3 + 2 844 c.545C>A c.(544-546)gCc>gAc p.A182D TDP1_uc010atm.3_Non-coding_Transcript|TDP1_uc001xxz.3_Missense_Mutation_p.A182D|TDP1_uc010atn.3_Missense_Mutation_p.A182D|TDP1_uc001xya.3_5'UTR|TDP1_uc001xyb.3_Non-coding_Transcript NM_018319 NP_060789 Q9NUW8 TYDP1_HUMAN Homo sapiens tyrosyl-DNA phosphodiesterase 1 (TDP1), transcript variant 1, mRNA. 182 cell death|double-strand break repair|single strand break repair cytoplasm|nucleus 3'-tyrosyl-DNA phosphodiesterase activity|double-stranded DNA binding|exonuclease activity|protein binding|single-stranded DNA binding NS(1)|endometrium(3)|kidney(2)|large_intestine(4)|lung(10)|ovary(3)|prostate(1)|urinary_tract(1) 25 all_cancers(154;0.185) COAD - Colon adenocarcinoma(157;0.23) AACTCTGGAGCCCTCCACATC 0.512000 Repair of DNA-protein crosslinks 4 48 0 0 1 0 0 SFMBT2 57713 broad.mit.edu 37 10 7242431 7242431 + Silent SNP C C A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr10:7242431C>A uc009xio.2 - 13 1594 c.1503G>T c.(1501-1503)gtG>gtT p.V501V SFMBT2_uc001ijn.2_Silent_p.V501V|SFMBT2_uc010qay.2_Intron NM_001018039 NP_001018049 Q5VUG0 SMBT2_HUMAN Homo sapiens Scm-like with four mbt domains 2 (SFMBT2), transcript variant 2, mRNA. 501 regulation of transcription, DNA-dependent nucleus NS(2)|breast(3)|central_nervous_system(4)|endometrium(7)|kidney(2)|large_intestine(26)|lung(34)|ovary(5)|pancreas(2)|skin(9)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1) 99 TCTTAACAGGCACTGTGGGCG 0.438000 28 36 0 0 1 0 0 ZDBF2 57683 broad.mit.edu 37 2 207169562 207169562 + Missense_Mutation SNP G G A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr2:207169562G>A uc002vbp.2 + 4 560 c.310G>A c.(310-312)Gaa>Aaa p.E104K NM_020923 NP_065974 Q9HCK1 ZDBF2_HUMAN Homo sapiens zinc finger, DBF-type containing 2 (ZDBF2), mRNA. 104 nucleic acid binding|zinc ion binding endometrium(4)|kidney(5)|large_intestine(28)|lung(50)|ovary(4)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(1) 95 GGATGCTACCGAAGAGAGACC 0.458000 17 30 0 0 1 0 0 NOD2 64127 broad.mit.edu 37 16 50759417 50759417 + Missense_Mutation SNP T T A TCGA-EL-A3T8-01A-21D-A22D-08 TCGA-EL-A3T8-11A-11D-A22D-08 Untested Somatic Phase_I WXS none Illumina GAIIx 47a0cb63-dd19-49fe-983d-a2e786795355 e475f95d-8efb-4df4-9682-9608c5081ea7 g.chr16:50759417T>A uc002egm.1 + 9 3005 c.2900T>A c.(2899-2901)cTc>cAc p.L967H NOD2_uc010vgq.1_Missense_Mutation_p.L12H NM_022162 NP_071445 Q9HC29 NOD2_HUMAN Homo sapiens nucleotide-binding oligomerization domain containing 2 (NOD2), mRNA. 967 JNK cascade|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|Toll signaling pathway|activation of MAPK activity involved in innate immune response|cytokine production involved in immune response|detection of bacterium|detection of muramyl dipeptide|negative regulation of macrophage apoptosis|nucleotide-binding oligomerization domain containing 2 signaling pathway|positive regulation of B cell activation|positive regulation of ERK1 and ERK2 cascade|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of JNK cascade|positive regulation of NF-kappaB transcription factor activity|positive regulation of Notch signaling pathway|positive regulation of dendritic cell antigen processing and presentation|positive regulation of epithelial cell proliferation|positive regulation of gamma-delta T cell activation|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-10 production|positive regulation of interleukin-17 production|positive regulation of interleukin-6 production|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of prostaglandin-E synthase activity|positive regulation of prostaglandin-endoperoxide synthase activity|positive regulation of stress-activated MAPK cascade|positive regulation of tumor necrosis factor production|positive regulation of type 2 immune response|protein oligomerization|stress-activated MAPK cascade|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway cell surface|cytosol|plasma membrane|vesicle ATP binding|CARD domain binding|muramyl dipeptide binding|protein kinase binding p.L967L(2) cervix(1)|endometrium(5)|kidney(3)|large_intestine(7)|lung(30)|ovary(3)|skin(3) 52 all_cancers(37;0.0156) GAGAACCATCTCCAGGATGAA 0.413000 3 90 0 0 1 0 0