Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut C22orf31 25770 broad.mit.edu 37 22 29456530 29456530 + Missense_Mutation SNP G G C TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr22:29456530G>C uc003aej.1 - 1 432 c.305C>G c.(304-306)tCg>tGg p.S102W NM_015370 NP_056185 O95567 CV031_HUMAN Homo sapiens chromosome 22 open reading frame 31 (C22orf31), mRNA. 102 cervix(1)|endometrium(1)|kidney(17)|large_intestine(2)|lung(4)|prostate(1)|skin(1) 27 TAATCTCTTCGAGAGTTTTCC 0.483000 3 141 0 0 1 0 0 C11orf2 738 broad.mit.edu 37 11 64878010 64878010 + Missense_Mutation SNP G G C TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr11:64878010G>C uc001ocr.1 + 7 1975 c.1935G>C c.(1933-1935)aaG>aaC p.K645N TM7SF2_uc001oct.3_5'Flank|TM7SF2_uc010rny.2_5'Flank|TM7SF2_uc001ocu.3_5'Flank|TM7SF2_uc001ocv.3_5'Flank|C11orf2_uc001ocs.1_Missense_Mutation_p.K521N NM_013265 NP_037397 Q9UID3 FFR_HUMAN Homo sapiens chromosome 11 open reading frame 2 (C11orf2), mRNA. 645 lipid transport|protein transport Golgi apparatus|integral to membrane cervix(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(10)|prostate(1) 15 ACTCCAGCAAGAGGACTTTCT 0.637000 OREG0021071 type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip) 4 193 0 0 1 0 0 MAGED2 10916 broad.mit.edu 37 X 54841696 54841696 + Missense_Mutation SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chrX:54841696C>T uc004dtk.1 + 11 1496 c.1402C>T c.(1402-1404)Ccc>Tcc p.P468S MAGED2_uc004dtl.1_Missense_Mutation_p.P468S|MAGED2_uc004dtm.1_Missense_Mutation_p.P383S|MAGED2_uc004dtn.1_Missense_Mutation_p.P468S|MAGED2_uc004dto.1_Missense_Mutation_p.P442S NM_177433 NP_957516 Q9UNF1 MAGD2_HUMAN Homo sapiens melanoma antigen family D, 2 (MAGED2), transcript variant 2, mRNA. 468 MAGE. p.P468S(2) breast(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(8)|ovary(2)|prostate(1)|skin(1)|urinary_tract(1) 26 AAAGAAGGATCCCAAGGAATG 0.458000 4 70 0 0 1 0 0 PRRG3 79057 broad.mit.edu 37 X 150869382 150869382 + Silent SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chrX:150869382C>T uc022cgt.1 + 3 622 c.573C>T c.(571-573)ccC>ccT p.P191P PRRG3_uc004few.2_Silent_p.P191P NM_024082 NP_076987 Q9BZD7 TMG3_HUMAN Homo sapiens proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) (PRRG3), transcript variant 1, mRNA. 191 extracellular region|integral to membrane calcium ion binding NS(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(1)|lung(6)|ovary(3)|prostate(2)|skin(3) 24 Acute lymphoblastic leukemia(192;6.56e-05) CCACCCCTCCCCCCTCCTACG 0.647000 4 63 0 0 1 0 0 LRRC32 2615 broad.mit.edu 37 11 76371702 76371702 + Missense_Mutation SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr11:76371702C>T uc001oxq.4 - 2 1178 c.935G>A c.(934-936)cGc>cAc p.R312H LRRC32_uc001oxr.4_Missense_Mutation_p.R312H|LRRC32_uc010rsf.2_Missense_Mutation_p.R312H NM_005512 NP_005503 Q14392 LRC32_HUMAN Homo sapiens leucine rich repeat containing 32 (LRRC32), transcript variant 1, mRNA. 312 integral to plasma membrane endometrium(1)|large_intestine(3)|lung(26)|upper_aerodigestive_tract(1) 31 GGAAAGGGGGCGGCCGCTGGC 0.622000 7 44 0 0 1 0 0 PRUNE2 158471 broad.mit.edu 37 9 79322343 79322343 + Missense_Mutation SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr9:79322343C>T uc010mpk.3 - 7 4971 c.4847G>A c.(4846-4848)cGc>cAc p.R1616H PRUNE2_uc022bih.1_Missense_Mutation_p.R1438H NM_015225 NP_056040 Q8WUY3 PRUN2_HUMAN Homo sapiens prune homolog 2 (Drosophila) (PRUNE2), mRNA. 1616 G1 phase|apoptosis|induction of apoptosis cytoplasm metal ion binding|pyrophosphatase activity endometrium(1)|kidney(4)|large_intestine(3)|lung(7)|prostate(1) 16 AGGAGTTTTGCGATCAAAGCT 0.353000 4 56 0 0 1 0 0 STK36 27148 broad.mit.edu 37 2 219561866 219561866 + Silent SNP A A G TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr2:219561866A>G uc002viu.3 + 22 2970 c.2691A>G c.(2689-2691)gcA>gcG p.A897A STK36_uc002viv.3_Silent_p.A876A|STK36_uc002vix.3_5'UTR NM_015690 NP_056505 Q9NRP7 STK36_HUMAN Homo sapiens serine/threonine kinase 36 (STK36), transcript variant 1, mRNA. 897 cilium assembly|positive regulation of hh target transcription factor activity|positive regulation of smoothened signaling pathway|post-embryonic development aggresome|cytoplasm|focal adhesion|intermediate filament cytoskeleton|nucleus ATP binding|protein serine/threonine kinase activity|transcription factor binding biliary_tract(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(6)|lung(20)|ovary(4)|prostate(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1) 52 Renal(207;0.0915) Epithelial(149;9.65e-07)|all cancers(144;0.000174)|LUSC - Lung squamous cell carcinoma(224;0.00813)|Lung(261;0.00984) AGGCATCTGCACAGGAAGGGG 0.537000 5 235 0 0 1 0 0