Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
STAG3	10734	broad.mit.edu	37	7	99780445	99780445	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr7:99780445G>A	ENST00000426455.1	+	4	726	c.319G>A	c.(319-321)Gcc>Acc	p.A107T	STAG3_ENST00000394018.2_Missense_Mutation_p.A107T|STAG3_ENST00000317296.5_Missense_Mutation_p.A107T			Q9UJ98	STAG3_HUMAN	stromal antigen 3	107					chromosome segregation|synaptonemal complex assembly	chromosome, centromeric region|meiotic cohesin complex|synaptonemal complex	binding			breast(1)|central_nervous_system(2)|endometrium(6)|kidney(3)|large_intestine(11)|lung(30)|ovary(5)|prostate(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)	66	Lung NSC(181;0.0181)|all_lung(186;0.0284)|Esophageal squamous(72;0.0439)					TGTGAAAGCCGCCAAAAGTGA	0.463000													5	303					0	0	0.000602	0	0
TMEM138	51524	broad.mit.edu	37	11	61136166	61136166	+	Missense_Mutation	SNP	G	G	C			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr11:61136166G>C	ENST00000278826.6	+	5	1033	c.474G>C	c.(472-474)atG>atC	p.M158I	TMEM138_ENST00000381787.2_Missense_Mutation_p.M100I	NM_016464.4	NP_057548.1	Q9NPI0	TM138_HUMAN	transmembrane protein 138	158						integral to membrane				central_nervous_system(1)|large_intestine(2)|lung(1)|upper_aerodigestive_tract(1)	5						AGGAGTTCATGCAAGTTCGAA	0.498000													3	40					0	0	0.004672	0	0
TCF7L2	6934	broad.mit.edu	37	10	114903693	114903693	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr10:114903693C>T	ENST00000545257.1	+	7	1204	c.697C>T	c.(697-699)Cct>Tct	p.P233S	TCF7L2_ENST00000369395.1_Missense_Mutation_p.P258S|TCF7L2_ENST00000352065.5_Missense_Mutation_p.P210S|TCF7L2_ENST00000536810.1_Missense_Mutation_p.P233S|TCF7L2_ENST00000542695.1_5'UTR|TCF7L2_ENST00000543371.1_Missense_Mutation_p.P233S|TCF7L2_ENST00000538897.1_Missense_Mutation_p.P233S|TCF7L2_ENST00000349937.2_Missense_Mutation_p.P233S|TCF7L2_ENST00000355717.4_Missense_Mutation_p.P257S|TCF7L2_ENST00000369389.1_5'UTR|TCF7L2_ENST00000369397.4_Missense_Mutation_p.P210S|TCF7L2_ENST00000534894.1_Missense_Mutation_p.P233S|TCF7L2_ENST00000355995.4_Missense_Mutation_p.P233S			Q9NQB0	TF7L2_HUMAN	transcription factor 7-like 2 (T-cell specific, HMG-box)	233	Mediates interaction with MAD2L2.|Pro-rich.				anti-apoptosis|blood vessel development|canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition|cell cycle arrest|cell proliferation|fat cell differentiation|glucose homeostasis|maintenance of DNA repeat elements|myoblast cell fate commitment|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|pancreas development|positive regulation of heparan sulfate proteoglycan biosynthetic process|positive regulation of insulin secretion|positive regulation of protein binding|positive regulation of protein export from nucleus|positive regulation of protein kinase B signaling cascade|positive regulation of transcription from RNA polymerase II promoter|regulation of hormone metabolic process|regulation of smooth muscle cell proliferation|response to glucose stimulus	beta-catenin-TCF7L2 complex|PML body|protein-DNA complex	armadillo repeat domain binding|beta-catenin binding|gamma-catenin binding|nuclear hormone receptor binding|protein kinase binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|transcription regulatory region DNA binding		VTI1A/TCF7L2(8)	central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(24)|liver(2)|lung(8)|ovary(1)|skin(1)	41		Breast(234;0.058)|Colorectal(252;0.0615)		Epithelial(162;0.00554)|all cancers(201;0.02)		AATCCCACGGCCTCCGCACCC	0.522000			T	VTI1A	colorectal								15	38					0	0	0.004007	0	0
NPAS2	4862	broad.mit.edu	37	2	101554284	101554284	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr2:101554284C>T	ENST00000335681.5	+	5	628	c.343C>T	c.(343-345)Cct>Tct	p.P115S	NPAS2_ENST00000542504.1_Missense_Mutation_p.P180S|NPAS2_ENST00000486017.1_3'UTR	NM_002518.3	NP_002509.2	Q99743	NPAS2_HUMAN	neuronal PAS domain protein 2	115	PAS 1.				central nervous system development|positive regulation of transcription from RNA polymerase II promoter|rhythmic process	transcription factor complex	DNA binding|Hsp90 protein binding|sequence-specific DNA binding transcription factor activity|signal transducer activity			cervix(1)|endometrium(3)|large_intestine(7)|lung(9)|ovary(3)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29						CAGTATCACGCCTCTCCTTGG	0.453000													14	161					0	0	0.002450	0	0
HLA-C	3107	broad.mit.edu	37	6	31239616	31239616	+	Missense_Mutation	SNP	C	C	A	rs150810080	byFrequency	TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr6:31239616C>A	ENST00000383329.3	-	2	117	c.103G>T	c.(103-105)Gcc>Tcc	p.A35S	HLA-C_ENST00000376228.5_Missense_Mutation_p.A35S			Q9TNN7	1C05_HUMAN	major histocompatibility complex, class I, C	35	Alpha-1.				antigen processing and presentation of peptide antigen via MHC class I|interferon-gamma-mediated signaling pathway|interspecies interaction between organisms|regulation of immune response|type I interferon-mediated signaling pathway	integral to membrane|MHC class I protein complex				central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(2)|lung(4)|prostate(4)|skin(2)|upper_aerodigestive_tract(1)	17						CGGGACACGGCGGTGTCGAAA	0.721000													4	38					0.000602214	0.00110406	0.000602	1	0
CHD7	55636	broad.mit.edu	37	8	61735125	61735125	+	Silent	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr8:61735125C>T	ENST00000423902.2	+	12	3500	c.3021C>T	c.(3019-3021)ctC>ctT	p.L1007L	CHD7_ENST00000525508.1_Silent_p.L1007L|CHD7_ENST00000524602.1_Intron	NM_017780.3	NP_060250.2	Q9P2D1	CHD7_HUMAN	chromodomain helicase DNA binding protein 7	1007	Helicase ATP-binding.				central nervous system development|chromatin modification|cognition|cranial nerve development|face development|heart morphogenesis|in utero embryonic development|inner ear morphogenesis|nose development|palate development|regulation of growth hormone secretion|regulation of transcription, DNA-dependent|retina development in camera-type eye|skeletal system development|T cell differentiation|transcription, DNA-dependent	nucleus	ATP binding|chromatin binding|DNA binding|helicase activity			NS(1)|breast(6)|central_nervous_system(8)|cervix(2)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(16)|lung(49)|ovary(4)|pancreas(2)|prostate(4)|skin(2)|urinary_tract(3)	123		all_cancers(86;0.2)|all_lung(136;0.0402)|Lung NSC(129;0.0459)|all_epithelial(80;0.0477)	BRCA - Breast invasive adenocarcinoma(89;0.143)			TTACATTTCTCTATGAGATAT	0.393000													18	132					0	0	0.001523	0	0
PRPF8	10594	broad.mit.edu	37	17	1564035	1564035	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr17:1564035C>T	ENST00000572621.1	-	28	4860	c.4595G>A	c.(4594-4596)cGt>cAt	p.R1532H	PRPF8_ENST00000304992.6_Missense_Mutation_p.R1532H			Q6P2Q9	PRP8_HUMAN	pre-mRNA processing factor 8	1532						catalytic step 2 spliceosome|nuclear speck|U5 snRNP	protein binding|RNA binding			NS(1)|autonomic_ganglia(1)|breast(2)|endometrium(11)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(13)|lung(24)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(5)|urinary_tract(3)	77				UCEC - Uterine corpus endometrioid carcinoma (25;0.0855)		GGTGAATCTACGATTGGGAAT	0.502000													5	59					0	0	0.000602	0	0
MKI67	4288	broad.mit.edu	37	10	129906562	129906562	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr10:129906562C>T	ENST00000368654.3	-	13	3917	c.3542G>A	c.(3541-3543)gGa>gAa	p.G1181E	MKI67_ENST00000368653.3_Missense_Mutation_p.G821E	NM_002417.4	NP_002408.3	P46013	KI67_HUMAN	marker of proliferation Ki-67	1181	16 X 122 AA approximate repeats.				cell proliferation	nucleolus	ATP binding|protein C-terminus binding			NS(2)|autonomic_ganglia(1)|breast(2)|central_nervous_system(2)|cervix(2)|endometrium(14)|haematopoietic_and_lymphoid_tissue(5)|kidney(7)|large_intestine(30)|lung(64)|ovary(4)|pancreas(1)|prostate(4)|skin(2)|soft_tissue(1)|stomach(10)|upper_aerodigestive_tract(4)|urinary_tract(4)	159		all_epithelial(44;2.12e-05)|all_lung(145;0.00679)|Lung NSC(174;0.00998)|all_neural(114;0.0936)|Colorectal(57;0.14)|Breast(234;0.166)|Melanoma(40;0.203)				CTCATCACCTCCTGCTGGTTT	0.468000													15	261					0	0	0.002450	0	0
PPP1R12B	4660	broad.mit.edu	37	1	202531948	202531948	+	Silent	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr1:202531948C>T	ENST00000406302.3	+	20	2703	c.2550C>T	c.(2548-2550)taC>taT	p.Y850Y	PPP1R12B_ENST00000336894.4_Silent_p.Y850Y|PPP1R12B_ENST00000367270.4_Silent_p.Y76Y|PPP1R12B_ENST00000391959.3_Silent_p.Y76Y|PPP1R12B_ENST00000290419.5_3'UTR	NM_001197131.1|NM_002481.3	NP_001184060.1|NP_002472.2	O60237	MYPT2_HUMAN	protein phosphatase 1, regulatory subunit 12B	850					regulation of muscle contraction|signal transduction	cytoplasm	enzyme activator activity			central_nervous_system(1)|cervix(1)|endometrium(6)|kidney(1)|large_intestine(7)|lung(17)|ovary(4)|skin(3)|urinary_tract(1)	41			BRCA - Breast invasive adenocarcinoma(75;0.166)			GTGATTCTTACGGTGACCGGG	0.493000													4	135					0	0	0.000248	0	0
TXNL1	9352	broad.mit.edu	37	18	54293600	54293600	+	Nonsense_Mutation	SNP	G	G	A			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr18:54293600G>A	ENST00000217515.6	-	2	391	c.187C>T	c.(187-189)Cag>Tag	p.Q63*	TXNL1_ENST00000590954.1_Nonsense_Mutation_p.Q63*|TXNL1_ENST00000540155.1_5'UTR	NM_004786.2	NP_004777.1	O43396	TXNL1_HUMAN	thioredoxin-like 1	63	Thioredoxin.				cell redox homeostasis|electron transport chain|glycerol ether metabolic process|transport	cytoplasm	electron carrier activity|protein disulfide oxidoreductase activity			endometrium(1)|large_intestine(1)|lung(1)|urinary_tract(1)	4				READ - Rectum adenocarcinoma(59;0.193)|Colorectal(16;0.211)		ACCTGACACTGATGTACATCG	0.343000													7	114					0	0	0.003080	0	0
SIPA1L1	26037	broad.mit.edu	37	14	72117175	72117175	+	Missense_Mutation	SNP	C	C	G			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr14:72117175C>G	ENST00000555818.1	+	5	2290	c.1942C>G	c.(1942-1944)Cga>Gga	p.R648G	SIPA1L1_ENST00000381232.3_Missense_Mutation_p.R648G|SIPA1L1_ENST00000358550.2_Missense_Mutation_p.R648G|SIPA1L1_ENST00000537413.1_Missense_Mutation_p.R123G	NM_015556.1	NP_056371.1	O43166	SI1L1_HUMAN	signal-induced proliferation-associated 1 like 1	648	Rap-GAP.				actin cytoskeleton reorganization|activation of Rap GTPase activity|regulation of dendritic spine morphogenesis	cell junction|cytoplasm|dendritic spine|postsynaptic density|postsynaptic membrane|synaptosome	GTPase activator activity			NS(1)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(11)|kidney(1)|large_intestine(22)|liver(2)|lung(25)|ovary(3)|prostate(3)|skin(3)|stomach(1)	78				all cancers(60;0.00169)|BRCA - Breast invasive adenocarcinoma(234;0.00912)|OV - Ovarian serous cystadenocarcinoma(108;0.0109)		ATTGGGAGAGCGAGTTCGGCT	0.443000													8	69					0	0	0.003080	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				14	50					0	0	0.002450	0	0
AK9	221264	broad.mit.edu	37	6	109954219	109954219	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr6:109954219C>T	ENST00000424296.2	-	12	1237	c.1161G>A	c.(1159-1161)atG>atA	p.M387I	AK9_ENST00000285397.5_Missense_Mutation_p.M387I|AK9_ENST00000368948.2_Missense_Mutation_p.M387I|AK9_ENST00000341338.6_5'UTR	NM_001145128.2	NP_001138600.2			adenylate kinase 9																		GTGGTCCTGGCATAGGTGGAA	0.373000													14	36					0	0	0.004007	0	0
RP11-417J8.6	0	broad.mit.edu	37	1	142713977	142713977	+	RNA	DEL	T	T	-			TCGA-BJ-A45H-01A-12D-A23U-08	TCGA-BJ-A45H-10A-01D-A23U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4bdbc383-8f81-410a-833e-1f039ceabddf	8cb61ce1-4085-4752-9f1e-91d7c1fee6ab	g.chr1:142713977delT	ENST00000369381.2	-	0	628																											ATCCATATACTAAAAAGGTTA	0.294													3	4	---	---	---	---