Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut NBPF10 100132406 broad.mit.edu 37 1 145302714 145302714 + Silent SNP A A G rs9424867 TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr1:145302714A>G ENST00000342960.5 + 8 1187 c.1152A>G c.(1150-1152)ttA>ttG p.L384L NBPF10_ENST00000369338.1_Silent_p.L113L|NBPF10_ENST00000369339.2_Silent_p.L113L|RP11-458D21.5_ENST00000468030.1_3'UTR NM_001039703.4 NP_001034792.4 A6NDV3 A6NDV3_HUMAN neuroblastoma breakpoint family, member 10 384 p.L113L(3)|p.L384L(3) NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2) 73 all_hematologic(923;0.032) Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258) AGGAGAAGTTACGGGAAGGGA 0.527000 7 198 0 0 0.000157383 0 0 LL22NC03-80A10.6 0 broad.mit.edu 37 22 22661474 22661474 + RNA SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr22:22661474C>T ENST00000426066.1 + 0 364 NR_027293.1 CCCTCAGATGCGTCTGAAGAA 0.493000 7 63 0 0 0.000442599 0 0 MAGED2 10916 broad.mit.edu 37 X 54841696 54841696 + Missense_Mutation SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chrX:54841696C>T ENST00000375068.1 + 12 1635 c.1402C>T c.(1402-1404)Ccc>Tcc p.P468S MAGED2_ENST00000375053.2_Missense_Mutation_p.P468S|MAGED2_ENST00000375060.1_Missense_Mutation_p.P383S|MAGED2_ENST00000396224.1_Missense_Mutation_p.P468S|MAGED2_ENST00000375062.4_Missense_Mutation_p.P383S|MAGED2_ENST00000347546.3_Missense_Mutation_p.P412S|MAGED2_ENST00000343474.6_Missense_Mutation_p.P450S|MAGED2_ENST00000375058.1_Missense_Mutation_p.P468S|MAGED2_ENST00000218439.4_Missense_Mutation_p.P468S Q9UNF1 MAGD2_HUMAN melanoma antigen family D, 2 468 MAGE. p.P468S(1) breast(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(8)|ovary(2)|prostate(1)|skin(1)|urinary_tract(1) 26 AAAGAAGGATCCCAAGGAATG 0.458000 4 70 0 0 1.23904e-05 0 0 C22orf31 25770 broad.mit.edu 37 22 29456530 29456530 + Missense_Mutation SNP G G C TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr22:29456530G>C ENST00000216071.4 - 2 356 c.305C>G c.(304-306)tCg>tGg p.S102W NM_015370.1 NP_056185.1 O95567 CV031_HUMAN chromosome 22 open reading frame 31 102 cervix(1)|endometrium(1)|kidney(17)|large_intestine(2)|lung(4)|prostate(1)|skin(1) 27 TAATCTCTTCGAGAGTTTTCC 0.483000 3 141 0 0 6.4e-05 0 0 LRRC32 2615 broad.mit.edu 37 11 76371702 76371702 + Missense_Mutation SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr11:76371702C>T ENST00000407242.2 - 3 1177 c.935G>A c.(934-936)cGc>cAc p.R312H LRRC32_ENST00000464145.1_Intron|AP001189.4_ENST00000447519.1_RNA|LRRC32_ENST00000260061.5_Missense_Mutation_p.R312H|LRRC32_ENST00000404995.1_Missense_Mutation_p.R312H NM_005512.2 NP_005503.1 Q14392 LRC32_HUMAN leucine rich repeat containing 32 312 integral to plasma membrane endometrium(1)|large_intestine(3)|lung(26)|upper_aerodigestive_tract(1) 31 GGAAAGGGGGCGGCCGCTGGC 0.622000 7 44 0 0 0.000157383 0 0 VPS51 738 broad.mit.edu 37 11 64878010 64878010 + Missense_Mutation SNP G G C TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr11:64878010G>C ENST00000279281.3 + 8 2027 c.1935G>C c.(1933-1935)aaG>aaC p.K645N VPS51_ENST00000527646.1_3'UTR NM_013265.2 NP_037397.2 vacuolar protein sorting 51 homolog (S. cerevisiae) ACTCCAGCAAGAGGACTTTCT 0.637000 OREG0021071 type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip) 4 193 0 0 0.00024832 0 0 PRAMEF11 440560 broad.mit.edu 37 1 12887606 12887606 + Missense_Mutation SNP C C G rs58074988 TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr1:12887606C>G ENST00000535591.1 - 3 446 c.251G>C c.(250-252)tGc>tCc p.C84S NM_001146344.1 NP_001139816.1 O60813 PRA11_HUMAN PRAME family member 11 84 p.C84S(1) NS(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|lung(7)|pancreas(2)|skin(4)|urinary_tract(1) 27 ATTGAGGAAGCACCCATGGGC 0.483000 6 483 0 0 6.40141e-05 0 0 PRRG3 79057 broad.mit.edu 37 X 150869382 150869382 + Silent SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chrX:150869382C>T ENST00000370353.3 + 4 963 c.573C>T c.(571-573)ccC>ccT p.P191P PRRG3_ENST00000538575.1_Silent_p.P191P Q9BZD7 TMG3_HUMAN proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 191 extracellular region|integral to membrane calcium ion binding NS(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(1)|lung(6)|ovary(3)|prostate(2)|skin(3) 24 Acute lymphoblastic leukemia(192;6.56e-05) CCACCCCTCCCCCCTCCTACG 0.647000 4 63 0 0 1.23904e-05 0 0 STK36 27148 broad.mit.edu 37 2 219561866 219561866 + Silent SNP A A G TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr2:219561866A>G ENST00000295709.3 + 23 2970 c.2691A>G c.(2689-2691)gcA>gcG p.A897A STK36_ENST00000440309.1_Silent_p.A897A|STK36_ENST00000392105.3_Silent_p.A876A|STK36_ENST00000392106.2_Silent_p.A876A NM_015690.4 NP_056505.2 Q9NRP7 STK36_HUMAN serine/threonine kinase 36 897 cilium assembly|positive regulation of hh target transcription factor activity|positive regulation of smoothened signaling pathway|post-embryonic development aggresome|cytoplasm|focal adhesion|intermediate filament cytoskeleton|nucleus ATP binding|protein serine/threonine kinase activity|transcription factor binding biliary_tract(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(6)|lung(20)|ovary(4)|prostate(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1) 52 Renal(207;0.0915) Epithelial(149;9.65e-07)|all cancers(144;0.000174)|LUSC - Lung squamous cell carcinoma(224;0.00813)|Lung(261;0.00984) AGGCATCTGCACAGGAAGGGG 0.537000 5 235 0 0 3.59834e-05 0 0 RP11-146E13.4 0 broad.mit.edu 37 14 19857036 19857036 + RNA SNP A A G TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr14:19857036A>G ENST00000548109.1 + 0 72 CTGGATAATAAAGTTCATCTC 0.373000 5 129 0 0 1.23904e-05 0 0 RP11-156P1.3 0 broad.mit.edu 37 17 45127107 45127107 + RNA SNP C C G rs147409399 by1000genomes TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr17:45127107C>G ENST00000575173.1 - 0 418 CCTTCGTTCACCCAAGAGCAT 0.592000 5 113 0 0 1.23904e-05 0 0 NBPF10 100132406 broad.mit.edu 37 1 145367739 145367739 + Silent SNP A A G rs146714035 by1000genomes TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr1:145367739A>G ENST00000342960.5 + 83 10370 c.10335A>G c.(10333-10335)aaA>aaG p.K3445K NBPF10_ENST00000369338.1_Intron|NBPF10_ENST00000369339.2_Intron NM_001039703.4 NP_001034792.4 A6NDV3 A6NDV3_HUMAN neuroblastoma breakpoint family, member 10 3445 p.K3445K(4) NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2) 73 all_hematologic(923;0.032) Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258) ggaaggggaaaaaaagaaggg 0.413000 3 153 0 0 6.4e-05 0 0 PRUNE2 158471 broad.mit.edu 37 9 79322343 79322343 + Missense_Mutation SNP C C T TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr9:79322343C>T ENST00000428286.1 - 8 4970 c.3770G>A c.(3769-3771)cGc>cAc p.R1257H PRUNE2_ENST00000376718.3_Missense_Mutation_p.R1616H Q8WUY3 PRUN2_HUMAN prune homolog 2 (Drosophila) 1616 apoptosis|G1 phase|induction of apoptosis cytoplasm metal ion binding|pyrophosphatase activity endometrium(1)|kidney(4)|large_intestine(3)|lung(7)|prostate(1) 16 AGGAGTTTTGCGATCAAAGCT 0.353000 4 56 0 0 0.00024832 0 0 CHD2 1106 broad.mit.edu 37 15 93545433 93545434 + Frame_Shift_Ins INS - - A TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr15:93545433_93545434insA ENST00000394196.4 + 33 5232_5233 c.4164_4165insA c.(4162-4167)ataaaafs p.IK1388fs CHD2_ENST00000557381.1_Frame_Shift_Ins_p.IK1388fs NM_001271.3 NP_001262.3 O14647 CHD2_HUMAN chromodomain helicase DNA binding protein 2 1388 regulation of transcription from RNA polymerase II promoter nucleus ATP binding|ATP-dependent DNA helicase activity|DNA binding breast(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(5)|kidney(2)|large_intestine(10)|lung(17)|ovary(1)|prostate(2)|skin(2)|stomach(1)|urinary_tract(2) 47 Lung NSC(78;0.00976)|all_lung(78;0.016) BRCA - Breast invasive adenocarcinoma(143;0.0282)|OV - Ovarian serous cystadenocarcinoma(32;0.0814) AAAGTCCAATgaaaaaaaaaca 0.337 8 159 --- --- --- --- PRR25 388199 broad.mit.edu 37 16 863356 863372 + Frame_Shift_Del DEL GGACGCCGGACCGACAC GGACGCCGGACCGACAC - rs113623365 TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr16:863356_863372delGGACGCCGGACCGACAC ENST00000301698.1 + 3 704_720 c.704_720delGGACGCCGGACCGACAC c.(703-720)afs p.RTPDRH235fs NM_001013638.1 NP_001013660.1 Q96S07 PRR25_HUMAN proline rich 25 235 large_intestine(1)|lung(1)|skin(1) 3 GGACCGGCAAGGACGCCGGACCGACACGGCCTCCCCA 0.714 8 7 --- --- --- --- KDM6B 23135 broad.mit.edu 37 17 7751764 7751765 + Frame_Shift_Ins INS - - C rs146391855 TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr17:7751764_7751765insC ENST00000254846.5 + 11 2547_2548 c.2158_2159insC c.(2158-2160)cccfs p.P720fs KDM6B_ENST00000448097.2_Frame_Shift_Ins_p.P720fs NM_001080424.1 NP_001073893.1 O15054 KDM6B_HUMAN lysine (K)-specific demethylase 6B 720 Pro-rich. inflammatory response nucleus metal ion binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen central_nervous_system(1)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(3)|lung(18)|ovary(1)|pancreas(1)|skin(5) 37 AGCAGGCGTGGCCCCCCAACCC 0.584 11 195 --- --- --- --- AC008103.5 0 broad.mit.edu 37 22 18842473 18842473 + RNA DEL G G - rs66618606 TCGA-EM-A2CP-01A-11D-A17V-08 TCGA-EM-A2CP-10A-01D-A17V-08 Untested Somatic Phase_I WXS none Illumina GAIIx b8cd6882-be27-4742-bc63-3227d31bf704 e6101d92-5616-476e-8b38-8b6847ae3d48 g.chr22:18842473delG ENST00000412938.1 + 0 2208 AGCTGCTGGTGGGGAGGTCTT 0.647 7 15 --- --- --- ---