Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error rsID rsID_ref_var_alleles CAF normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumor_var_reads tumor_vaf normal_ref_reads_val normal_var_reads_val normal_vaf_val tumor_ref_reads_val tumor_var_reads_val tumor_vaf_val MID1 0 genome.wustl.edu 37 X 10427745 10427745 + Missense_Mutation SNP A A G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 X 10427745 10427745 A G SNP MID1 ENST00000317552 human ensembl 74_37 -1 known missense c.1388 p.V463A 1 pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Fibronectin_type3,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_Znf_RING,smart_Znf_B-box,smart_Bbox_C,smart_Fibronectin_type3,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Fibronectin_type3,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin 0 no_errors 0 0 0 51 0 0 27 9 25 168 0 0.00 75 43 36.44 ARMCX2 0 genome.wustl.edu 37 X 100911457 100911457 + Missense_Mutation SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 X 100911457 100911457 C T SNP ARMCX2 ENST00000328766 human ensembl 74_37 -1 known missense c.1118 p.R373H 1 NULL pfam_ARM-rpt_dom,superfamily_ARM-type_fold,smart_Armadillo 0 no_errors 0 0 0 81 0 0 26 16 37.21 155 0 0.00 74 44 36.97 AFF2 0 genome.wustl.edu 37 X 148069069 148069069 + Missense_Mutation SNP C C A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 X 148069069 148069069 C A SNP AFF2 ENST00000370460 human ensembl 74_37 1 known missense c.3796 p.L1266M 1 pfam_TF_AF4/FMR2 pfam_TF_AF4/FMR2 0 no_errors 0 0 0 10 0 0 23 3 11.54 268 0 0.00 222 11 4.70 IDS 0 genome.wustl.edu 37 X 148564527 148564527 + Missense_Mutation SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 X 148564527 148564527 C T SNP IDS ENST00000340855 human ensembl 74_37 -1 known missense c.1403 p.R468Q 1 superfamily_Alkaline_phosphatase_core pfam_Sulfatase,pfam_Phosphodiest/P_Trfase,superfamily_Alkaline_phosphatase_core 0 no_errors rs113993946 C->A,G,T 0 130 0 0 52 27 34.18 269 0 0.00 125 83 39.90 ENSG00000255168 0 genome.wustl.edu 37 1 145281625 145281625 + Silent SNP C C G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C G C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 1 145281625 145281625 C G SNP ENSG00000255168 ENST00000468030 human ensembl 74_37 1 known silent c.555 p.P185 0.997 smart_EG-like_dom,pfscan_EG-like_dom pfam_EG-like_dom,pfam_EGF_extracell,pfam_EGF-like_Ca-bd_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom 0 no_errors 0 0 0 124 0 0 130 17 11.56 171 0 0.00 188 17 8.29 ENSG00000237457 0 genome.wustl.edu 37 1 190449665 190449665 + RNA SNP T T C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 1 190449665 190449665 T C SNP ENSG00000237457 ENST00000424735 human ensembl 74_37 1 known rna NULL NULL 0.003 0 0 0 no_errors 0 0 0 18 0 0 7 5 35.71 360 0 0.00 256 98 27.68 RGS1 0 genome.wustl.edu 37 1 192548271 192548271 + Missense_Mutation SNP A A G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 1 192548271 192548271 A G SNP RGS1 ENST00000367459 human ensembl 74_37 1 known missense c.449 p.N150S 1 pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom 0 no_errors 0 0 0 81 0 0 140 62 30.54 308 0 0.00 270 111 29.13 CCSAP 0 genome.wustl.edu 37 1 229478671 229478671 + RNA SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 1 229478671 229478671 G A SNP CCSAP ENST00000483092 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 25 0 0 12 7 36.84 30 0 0.00 44 15 25.42 OR2W3 0 genome.wustl.edu 37 1 248059455 248059455 + Silent SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 1 248059455 248059455 C T SNP OR2W3 ENST00000360358 human ensembl 74_37 1 known silent c.567 p.C189 0.024 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 34 0 0 27 9 25 129 0 0.00 103 58 36.02 ODC1 0 genome.wustl.edu 37 2 10584662 10584662 + Missense_Mutation SNP C C A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 10584662 10584662 C A SNP ODC1 ENST00000234111 human ensembl 74_37 -1 known missense c.214 p.D72Y 1 pfam_De-COase2_N,prints_Orn_de-COase,prints_Orn/DAP/Arg_de-COase pfam_De-COase2_N,pfam_De-COase2_C,superfamily_Ala_racemase/Decarboxylase_C,prints_Orn_de-COase,prints_Orn/DAP/Arg_de-COase 0 no_errors 0 0 0 76 0 0 30 15 33.33 199 0 0.00 105 57 35.19 APLF 0 genome.wustl.edu 37 2 68753274 68753274 + Missense_Mutation SNP A A G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 68753274 68753274 A G SNP APLF ENST00000303795 human ensembl 74_37 1 known missense c.704 p.Q235R 0.671 NULL pfam_Znf_C2H2_APLF-like,superfamily_SMAD_FHA_domain 0 no_errors 0 0 0 22 0 0 28 17 36.96 247 1 0.40 120 79 39.70 SCN1A 0 genome.wustl.edu 37 2 166868749 166868749 + Missense_Mutation SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 166868749 166868749 G A SNP SCN1A ENST00000303395 human ensembl 74_37 -1 known missense c.3749 p.T1250M 0.984 NULL pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,prints_Na_channel_a1su,prints_Na_channel_asu,prints_PKD_2 0 no_errors rs140731963 G->A 0 27 0 0 40 14 25.93 269 0 0.00 122 66 35.11 TTN 0 genome.wustl.edu 37 2 179560833 179560833 + Silent SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 179560833 179560833 G A SNP TTN ENST00000342992 human ensembl 74_37 -1 known silent c.27234 p.D9078 0.021 superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom 0 no_errors rs587780979 G->A 0 69 0 0 46 12 20.69 306 1 0.33 195 127 39.32 HECW2 0 genome.wustl.edu 37 2 197182045 197182045 + Missense_Mutation SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 197182045 197182045 C T SNP HECW2 ENST00000260983 human ensembl 74_37 -1 known missense c.2387 p.R796H 1 NULL pfam_HECT,pfam_WW_dom,pfam_C2_dom,superfamily_HECT,superfamily_WW_dom,superfamily_C2_dom,smart_C2_dom,smart_WW_dom,smart_HECT,pfscan_HECT,pfscan_C2_dom,pfscan_WW_dom 0 no_errors 0 0 0 75 0 0 42 20 32.26 157 0 0.00 85 54 38.57 SPEG 0 genome.wustl.edu 37 2 220331922 220331922 + Missense_Mutation SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 220331922 220331922 G A SNP SPEG ENST00000312358 human ensembl 74_37 1 novel missense c.2908 p.V970M 1 pfscan_Ig-like_dom pfam_Ig_I-set,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom 0 no_errors rs377353278 G->A 0 40 0 0 6 10 62.5 63 0 0.00 43 21 32.81 SNED1 0 genome.wustl.edu 37 2 241992589 241992589 + Silent SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 241992589 241992589 G A SNP SNED1 ENST00000310397 human ensembl 74_37 1 known silent c.2103 p.P701 0 superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP pfam_EG-like_dom,pfam_Fibronectin_type3,pfam_Nidogen_extracell_dom,pfam_EGF_extracell,pfam_EGF-like_Ca-bd_dom,superfamily_Fibronectin_type3,superfamily_Sushi_SCR_CCP,smart_Nidogen_extracell_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Sushi_SCR_CCP,smart_Fibronectin_type3,pfscan_EG-like_dom,pfscan_Fibronectin_type3,pfscan_Sushi_SCR_CCP 0 no_errors 0 0 0 9 0 0 12 5 29.41 16 0 0.00 19 15 44.12 HDLBP 0 genome.wustl.edu 37 2 242192848 242192848 + Missense_Mutation SNP T T C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 242192848 242192848 T C SNP HDLBP ENST00000310931 human ensembl 74_37 -1 known missense c.1253 p.N418S 0 pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1 pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1 0 no_errors rs7578199 T->C 0 52 0 0 27 9 25 224 0 0.00 128 55 30.05 KIT 0 genome.wustl.edu 37 4 55593610 55593610 + Missense_Mutation SNP T T G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 4 55593610 55593610 T G SNP KIT ENST00000288135 human ensembl 74_37 1 known missense c.1676 p.V559G 1 pirsf_Tyr_kinase_CSF1/PDGF_rcpt,superfamily_Kinase-like_dom pirsf_Tyr_kinase_CSF1/PDGF_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom 0 no_errors rs121913517 T->A,C,G 0 40 0 0 54 26 32.5 408 0 0.00 389 125 24.32 GPR98 0 genome.wustl.edu 37 5 90059169 90059169 + Silent SNP G G C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G C G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 5 90059169 90059169 G C SNP GPR98 ENST00000405460 human ensembl 74_37 1 known silent c.12168 p.V4056 1 pfam_Calx_beta,smart_Calx_beta pfam_Calx_beta,pfam_EPTP,pfam_GPCR_2_secretin-like,pfam_GPS_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Gal_Oxase/kelch_b-propeller,smart_Calx_beta,pfscan_EAR,pfscan_GPS_dom,pfscan_GPCR_2-like 0 no_errors 0 0 0 28 0 0 24 10 29.41 274 0 0.00 147 62 29.38 SLC18B1 0 genome.wustl.edu 37 6 133095445 133095445 + Missense_Mutation SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 6 133095445 133095445 C T SNP SLC18B1 ENST00000275227 human ensembl 74_37 -1 known missense c.905 p.R302K 1 pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom 0 no_errors 0 0 0 106 0 0 79 31 28.18 193 1 0.51 113 64 35.96 MCMDC2 0 genome.wustl.edu 37 8 67790820 67790820 + Missense_Mutation SNP A A G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 8 67790820 67790820 A G SNP MCMDC2 ENST00000422365 human ensembl 74_37 1 known missense c.493 p.I165V 1 superfamily_NA-bd_OB-fold,smart_MCM_DNA-dep_ATPase pfam_MCM_DNA-dep_ATPase,superfamily_NA-bd_OB-fold,superfamily_P-loop_NTPase,smart_MCM_DNA-dep_ATPase 0 no_errors rs200037793 A->G 0.9998,0.0001997 37 0 0 99 50 33.56 304 0 0.00 156 85 35.27 GDF6 0 genome.wustl.edu 37 8 97157553 97157553 + Silent SNP C C G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C G C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 8 97157553 97157553 C G SNP GDF6 ENST00000287020 human ensembl 74_37 -1 known silent c.606 p.L202 0.998 pfam_TGF-b_N pfam_TGF-b_C,pfam_TGF-b_N,smart_TGF-b_C 0 no_errors 0 0 0 8 0 0 2 4 66.67 20 0 0.00 21 14 40.00 POP1 0 genome.wustl.edu 37 8 99169924 99169924 + Missense_Mutation SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 8 99169924 99169924 G A SNP POP1 ENST00000349693 human ensembl 74_37 1 known missense c.2500 p.G834S 0 NULL pfam_RNase_P/MRP_POP1,pfam_POPLD 0 no_errors 0 0 0 58 1 1.64 23 9 28.12 123 0 0.00 57 29 33.72 CARD17 0 genome.wustl.edu 37 11 104970124 104970124 + Missense_Mutation SNP G G T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 11 104970124 104970124 G T SNP CARD17 ENST00000375707 human ensembl 74_37 -1 known missense c.299 p.T100N 0 NULL pfam_CARD,superfamily_DEATH-like_dom,smart_CARD,pfscan_CARD 0 no_errors 0 0 0 47 0 0 38 14 26.92 210 2 0.94 109 52 32.30 CRIP2 0 genome.wustl.edu 37 14 105939835 105939835 + Missense_Mutation SNP A A C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A C A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 14 105939835 105939835 A C SNP CRIP2 ENST00000483017 human ensembl 74_37 1 putative missense c.251 p.Q84P 0.008 pfscan_Znf_LIM pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM 0 no_errors 0 0 0 58 0 0 12 8 40 66 0 0.00 44 36 44.44 ATP10A 0 genome.wustl.edu 37 15 25971102 25971102 + Silent SNP T T G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 15 25971102 25971102 T G SNP ATP10A ENST00000356865 human ensembl 74_37 -1 known silent c.975 p.A325 0.001 pfam_ATPase_P-typ_transduc_dom_A,tigrfam_ATPase_P-typ_Plipid-transp pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase 0 no_errors 0 0 0 19 0 0 8 4 33.33 73 0 0.00 37 22 37.29 ALPK3 0 genome.wustl.edu 37 15 85405949 85405949 + Nonsense_Mutation SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 15 85405949 85405949 C T SNP ALPK3 ENST00000258888 human ensembl 74_37 1 known nonsense c.4819 p.R1607* 1 superfamily_Kinase-like_dom,pfscan_MHCK_EF2_kinase pfam_MHCK_EF2_kinase,pfam_Ig_I-set,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_MHCK_EF2_kinase,pfscan_MHCK_EF2_kinase,pfscan_Ig-like_dom 0 no_errors 0 0 0 50 0 0 23 11 32.35 196 2 1.01 94 58 38.16 BRD7 0 genome.wustl.edu 37 16 50357576 50357576 + Nonsense_Mutation SNP A A C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A C A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 16 50357576 50357576 A C SNP BRD7 ENST00000394689 human ensembl 74_37 -1 known nonsense c.1365 p.Y455* 0.812 pfam_DUF3512 pfam_DUF3512,pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain 0 no_errors 0 0 0 77 0 0 16 18 52.94 85 0 0.00 19 30 61.22 FOXN1 0 genome.wustl.edu 37 17 26851036 26851036 + Missense_Mutation SNP A A G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 17 26851036 26851036 A G SNP FOXN1 ENST00000226247 human ensembl 74_37 1 known missense c.49 p.T17A 0.071 NULL pfam_TF_fork_head,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head 0 no_errors 0 0 0 130 0 0 79 20 20.2 51 0 0.00 58 22 27.50 USP32 0 genome.wustl.edu 37 17 58289456 58289456 + Missense_Mutation SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 17 58289456 58289456 C T SNP USP32 ENST00000300896 human ensembl 74_37 -1 known missense c.2108 p.R703H 1 NULL pfam_Peptidase_C19/C67,pfam_Pept_C19_DUSP,smart_EF_hand_dom,smart_Pept_C19_DUSP,pfscan_EF_hand_dom,pfscan_Peptidase_C19/C67,prints_Recoverin 0 no_errors 0 0 0 57 0 0 152 16 9.52 395 2 0.50 394 61 13.32 ENSG00000263887 0 genome.wustl.edu 37 17 60366722 60366722 + RNA SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 17 60366722 60366722 C T SNP ENSG00000263887 ENST00000602493 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 39 0 0 100 20 16.53 229 2 0.87 268 85 24.08 CARD14 0 genome.wustl.edu 37 17 78182112 78182112 + Missense_Mutation SNP A A G TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 17 78182112 78182112 A G SNP CARD14 ENST00000344227 human ensembl 74_37 1 known missense c.2983 p.K995E 1 superfamily_P-loop_NTPase pfam_CARD,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,superfamily_PDZ,pfscan_CARD,pfscan_PDZ,pfscan_Guanylate_kin-like 0 no_errors 0 0 0 110 0 0 56 28 33.33 79 1 1.25 77 31 28.70 MUC16 0 genome.wustl.edu 37 19 9016675 9016675 + Missense_Mutation SNP G G T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 19 9016675 9016675 G T SNP MUC16 ENST00000397910 human ensembl 74_37 -1 known missense c.38062 p.L12688I 0 NULL pfam_SEA_dom,smart_SEA_dom,pfscan_SEA_dom 0 no_errors 0 0 0 130 0 0 46 25 35.21 51 0 0.00 20 7 25.93 MYBL2 0 genome.wustl.edu 37 20 42331285 42331285 + Silent SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 20 42331285 42331285 C T SNP MYBL2 ENST00000217026 human ensembl 74_37 1 known silent c.1107 p.T369 0.962 NULL pfam_C-myb_C,pfam_SANT/Myb,superfamily_Homeodomain-like,smart_SANT/Myb,pfscan_Myb-like_dom 0 no_errors rs181688716 C->T 0.9996,0.0003994 35 0 0 23 10 30.3 80 0 0.00 79 32 28.83 CASS4 0 genome.wustl.edu 37 20 55028090 55028090 + Missense_Mutation SNP G G A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 20 55028090 55028090 G A SNP CASS4 ENST00000360314 human ensembl 74_37 1 known missense c.1858 p.E620K 0.961 pfam_CAS_DUF3513 pfam_Serine_rich,pfam_CAS_DUF3513,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain 0 no_errors 0 0 0 62 0 0 52 28 35 322 0 0.00 260 78 23.08 CASS4 0 genome.wustl.edu 37 20 55028092 55028092 + Missense_Mutation SNP A A T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 20 55028092 55028092 A T SNP CASS4 ENST00000360314 human ensembl 74_37 1 known missense c.1860 p.E620D 0 pfam_CAS_DUF3513 pfam_Serine_rich,pfam_CAS_DUF3513,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain 0 no_errors 0 0 0 61 0 0 53 28 34.57 322 0 0.00 261 79 23.24 KLHL29 0 genome.wustl.edu 37 2 23919269 23919270 + Frame_Shift_Ins INS - - CCTCGTCT TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 - - - CCTCGTCT - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 2 23919269 23919270 0 CCTCGTCT INS KLHL29 ENST00000486442 human ensembl 74_37 1 known frame_shift_ins c.1991_1992 p.S668fs 1.000:1.000 smart_Kelch_1 pfam_Kelch_1,pfam_BACK,pfam_Kelch_2,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like 0 no_errors 0 0 0 46 0 0 21 8 27.59 164 0 0.00 119 12 9.16 CHD8 0 genome.wustl.edu 37 14 21868216 21868216 + Frame_Shift_Del DEL C C - TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 14 21868216 21868216 C 0 DEL CHD8 ENST00000399982 human ensembl 74_37 -1 known frame_shift_del c.4741 p.V1581fs 1 NULL pfam_SNF2_N,pfam_Chromo_domain,pfam_BRK_domain,pfam_Helicase_C,pfam_Helicase/UvrB_dom,pfam_DNA/RNA_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,smart_BRK_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow 0 no_errors 0 0 0 42 0 0 30 20 40 219 0 0.00 137 63 31.50 QRICH2 0 genome.wustl.edu 37 17 74273351 74273351 + Frame_Shift_Del DEL G G - TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 17 74273351 74273351 G 0 DEL QRICH2 ENST00000262765 human ensembl 74_37 -1 known frame_shift_del c.4660 p.R1554fs 0.91 NULL NULL 0 no_errors 0 0 0 104 0 0 57 15 20.83 80 0 0.00 61 31 33.70 HMGB1P5 0 genome.wustl.edu 37 3 22424272 22424272 + RNA SNP T T C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 T T Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 3 22424272 22424272 T C SNP HMGB1P5 ENST00000451497 human ensembl 74_37 1 known rna NULL NULL 0.995 0 0 0 no_errors 0 0 0 21 0 0 40 6 13.04 0 0 0.00 0 0 0.00 ALG1L2 0 genome.wustl.edu 37 3 129810213 129810213 + RNA SNP C C T TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 3 129810213 129810213 C T SNP ALG1L2 ENST00000503500 human ensembl 74_37 1 known rna NULL NULL 0.97 0 0 0 no_errors rs557466292 C->T 0.9998,0.0001997 52 0 0 19 7 26.92 0 0 0.00 0 0 0.00 PPIA 0 genome.wustl.edu 37 7 44840986 44840986 + Missense_Mutation SNP A A C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 A A Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 7 44840986 44840986 A C SNP PPIA ENST00000468812 human ensembl 74_37 1 known missense c.463 p.K155Q 1 pfam_Cyclophilin-like_PPIase_dom,superfamily_Cyclophilin-like_PPIase_dom,pfscan_Cyclophilin-like_PPIase_dom pfam_Cyclophilin-like_PPIase_dom,superfamily_Cyclophilin-like_PPIase_dom,pfscan_Cyclophilin-like_PPIase_dom,prints_Cyclophilin-like_PPIase_dom 0 no_errors 0 0 0 45 1 2.17 34 6 15 0 0 0.00 0 0 0.00 MGC21881 0 genome.wustl.edu 37 9 66554510 66554510 + RNA SNP C C A TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 9 66554510 66554510 C A SNP MGC21881 ENST00000305709 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 429 0 0 252 34 11.76 0 0 0.00 0 0 0.00 GOLGA6L5 0 genome.wustl.edu 37 15 85053254 85053254 + RNA SNP T T C TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 T T Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 15 85053254 85053254 T C SNP GOLGA6L5 ENST00000414190 human ensembl 74_37 -1 known rna NULL NULL 0.973 0 0 0 no_errors 0 0 0 18 0 0 11 3 21.43 0 0 0.00 0 0 0.00 CTNND2 0 genome.wustl.edu 37 5 11385097 11385112 + Frame_Shift_Del DEL GCCGAGCCGCCGCGCT GCCGAGCCGCCGCGCT - TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 GCCGAGCCGCCGCGCT GCCGAGCCGCCGCGCT Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 5 11385097 11385112 GCCGAGCCGCCGCGCT 0 DEL CTNND2 ENST00000304623 human ensembl 74_37 -1 known frame_shift_del c.857_842 p.Q281fs 1.000:1.000:0.994:1.000:1.000:0.999:1.000:1.000:0.996:1.000:1.000:1.000:1.000:1.000:1.000:1.000 NULL pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo 0 no_errors 0 0 0 57 0 0 24 7 22.58 12 0 0.00 8 0 0.00 MED15 0 genome.wustl.edu 37 22 20918817 20918819 + In_Frame_Del DEL CAG CAG - TCGA-XU-A933-01A-11D-A423-09 TCGA-XU-A933-10A-01D-A426-09 CAG CAG Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq efc5c6fb-4660-49ff-acd5-ed6ae94a2881 11407dd0-5b1d-46b8-a640-3c2ae4071034 22 20918817 20918819 CAG 0 DEL MED15 ENST00000263205 human ensembl 74_37 1 known in_frame_del c.532_534 p.Q181in_frame_del 0.686:0.761:0.805 pfam_Mediator_Med15_met pfam_Mediator_Med15_met 0 no_errors 0 0 0 41 1 2.38 20 3 13.04 4 0 0.00 4 0 0.00