Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
NLGN4X	0	genome.wustl.edu	37	X	5947401	5947401	+	Missense_Mutation	SNP	C	C	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	X	5947401	5947401	C	A	SNP	NLGN4X	ENST00000381093	human	ensembl	74_37	-1	known	missense	c.605	p.G202V	0.993	pfam_CarbesteraseB,pfam_AB_hydrolase_3	pfam_CarbesteraseB,pfam_AB_hydrolase_3,prints_Neuroligin	0	no_errors	0	0	0	107	0	0	74	38	33.93	284	0	0.00	117	71	37.77
STARD8	0	genome.wustl.edu	37	X	67943847	67943847	+	Silent	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	X	67943847	67943847	G	A	SNP	STARD8	ENST00000374599	human	ensembl	74_37	1	known	silent	c.3078	p.P1026	0.983	pfam_START_lipid-bd_dom,smart_START_lipid-bd_dom,pfscan_START_lipid-bd_dom	pfam_START_lipid-bd_dom,pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,smart_START_lipid-bd_dom,pfscan_START_lipid-bd_dom,pfscan_RhoGAP_dom	0	no_errors	rs373631827	G->A	0	46	0	0	27	25	48.08	189	1	0.53	82	47	36.15
GPR119	0	genome.wustl.edu	37	X	129519407	129519407	+	Missense_Mutation	SNP	G	G	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	X	129519407	129519407	G	T	SNP	GPR119	ENST00000276218	human	ensembl	74_37	-1	known	missense	c.15	p.F5L	0.127	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	0	no_errors	0	0	0	47	0	0	26	23	46	291	0	0.00	148	93	38.59
ZFP92	0	genome.wustl.edu	37	X	152685753	152685753	+	Silent	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	X	152685753	152685753	C	T	SNP	ZFP92	ENST00000338647	human	ensembl	74_37	1	known	silent	c.228	p.D76	0	pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	0	no_errors	0	0	0	177	0	0	111	12	9.76	237	0	0.00	143	14	8.92
RHD	0	genome.wustl.edu	37	1	25655528	25655528	+	Silent	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	1	25655528	25655528	C	T	SNP	RHD	ENST00000342055	human	ensembl	74_37	1	putative	silent	c.1383	p.R461	0.003	NULL	pfam_NH4_transpt_AmtB-like_dom,superfamily_NH4_transpt_AmtB-like_dom,prints_RhesusRHD	0	no_errors	0	0	0	116	0	0	52	45	46.39	296	0	0.00	109	96	46.60
PDE4B	0	genome.wustl.edu	37	1	66384468	66384468	+	Silent	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	1	66384468	66384468	G	A	SNP	PDE4B	ENST00000329654	human	ensembl	74_37	1	known	silent	c.231	p.L77	0.964	NULL	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom,prints_PDEase	0	no_errors	0	0	0	51	0	0	42	9	17.65	276	0	0.00	162	19	10.50
FAM46C	0	genome.wustl.edu	37	1	118166566	118166566	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	1	118166566	118166566	C	T	SNP	FAM46C	ENST00000369448	human	ensembl	74_37	1	known	missense	c.1076	p.P359L	1	NULL	pfam_DUF1693	0	no_errors	rs557599465	C->T	0	28	0	0	27	14	34.15	363	0	0.00	163	82	33.47
LBX2	0	genome.wustl.edu	37	2	74726543	74726543	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	2	74726543	74726543	G	C	SNP	LBX2	ENST00000377566	human	ensembl	74_37	-1	known	missense	c.122	p.P41R	0.059	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	0	no_errors	0	0	0	111	1	0.89	54	31	36.47	139	0	0.00	42	26	38.24
NR4A2	0	genome.wustl.edu	37	2	157184975	157184975	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	2	157184975	157184975	C	T	SNP	NR4A2	ENST00000539077	human	ensembl	74_37	-1	known	missense	c.968	p.R323Q	1	pfam_Znf_hrmn_rcpt,smart_Znf_hrmn_rcpt,pfscan_Znf_hrmn_rcpt,prints_Znf_hrmn_rcpt	pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_NURR_rcpt,prints_Nuc_orph_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_Retinoic_acid_rcpt	0	no_errors	0	0	0	84	0	0	33	24	42.11	343	0	0.00	105	85	44.50
ITIH4	0	genome.wustl.edu	37	3	52858575	52858575	+	Nonsense_Mutation	SNP	C	C	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	3	52858575	52858575	C	A	SNP	ITIH4	ENST00000266041	human	ensembl	74_37	-1	known	nonsense	c.883	p.E295*	0.996	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_VIT,pfam_ITI_HC_C,pfam_VWF_A,smart_VIT,smart_VWF_A,pfscan_VWF_A	0	no_errors	0	0	0	35	0	0	19	9	32.14	365	0	0.00	115	87	42.86
SLC7A14	0	genome.wustl.edu	37	3	170185016	170185016	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	3	170185016	170185016	C	T	SNP	SLC7A14	ENST00000231706	human	ensembl	74_37	-1	known	missense	c.2143	p.E715K	0.986	NULL	pfam_AA-permease/SLC12A_dom	0	no_errors	rs530931888	C->T	0.9998,0.0001997	43	0	0	20	7	25.93	247	0	0.00	82	32	28.07
ENSG00000249275	0	genome.wustl.edu	37	4	158559166	158559166	+	RNA	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	4	158559166	158559166	C	T	SNP	ENSG00000249275	ENST00000507296	human	ensembl	74_37	1	known	rna	NULL	NULL	0	0	0	0	no_errors	0	0	0	22	0	0	6	7	53.85	27	0	0.00	12	9	42.86
DNAH5	0	genome.wustl.edu	37	5	13916560	13916560	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	5	13916560	13916560	G	A	SNP	DNAH5	ENST00000265104	human	ensembl	74_37	-1	known	missense	c.1094	p.S365F	0.975	pfam_Dynein_heavy_dom-1	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	0	no_errors	0	0	0	152	1	0.65	72	66	47.83	217	0	0.00	116	85	42.29
DACT2	0	genome.wustl.edu	37	6	168708585	168708585	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	6	168708585	168708585	G	C	SNP	DACT2	ENST00000366795	human	ensembl	74_37	-1	known	missense	c.1852	p.R618G	0.005	NULL	NULL	0	no_errors	0	0	0	23	0	0	12	5	29.41	36	0	0.00	5	11	68.75
ELFN1	0	genome.wustl.edu	37	7	1785871	1785871	+	Missense_Mutation	SNP	G	G	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	7	1785871	1785871	G	T	SNP	ELFN1	ENST00000424383	human	ensembl	74_37	1	known	missense	c.1639	p.D547Y	0.996	NULL	superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C	0	no_errors	0	0	0	16	0	0	6	3	33.33	86	0	0.00	25	22	46.81
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	554	0	0	236	178	42.89	170	0	0.00	96	50	34.25
WNK2	0	genome.wustl.edu	37	9	96052266	96052266	+	Missense_Mutation	SNP	A	A	G			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	9	96052266	96052266	A	G	SNP	WNK2	ENST00000297954	human	ensembl	74_37	1	known	missense	c.4984	p.K1662E	0.846	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Kinase_OSR1/WNK_CCT,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	0	no_errors	0	0	0	21	0	0	7	8	53.33	169	0	0.00	79	47	37.30
MAMDC4	0	genome.wustl.edu	37	9	139748159	139748159	+	RNA	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	9	139748159	139748159	C	T	SNP	MAMDC4	ENST00000485732	human	ensembl	74_37	1	known	rna	NULL	NULL	0.001	0	0	0	no_errors	0	0	0	36	0	0	17	12	38.71	41	0	0.00	12	10	43.48
OR4C16	0	genome.wustl.edu	37	11	55339695	55339695	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	11	55339695	55339695	G	A	SNP	OR4C16	ENST00000314634	human	ensembl	74_37	1	known	missense	c.92	p.R31H	0	prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	0	no_errors	rs374191202	G->A,T	0.9998,0.0001997,.	76	0	0	34	27	43.55	339	1	0.29	142	74	33.94
MAP4K2	0	genome.wustl.edu	37	11	64563812	64563812	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	11	64563812	64563812	G	A	SNP	MAP4K2	ENST00000294066	human	ensembl	74_37	-1	known	missense	c.1684	p.R562W	1	pfam_Citron,smart_Citron	pfam_Prot_kinase_dom,pfam_Citron,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Citron,pfscan_Prot_kinase_dom	0	no_errors	0	0	0	44	0	0	28	17	37.78	193	0	0.00	59	65	52.42
TBCEL	0	genome.wustl.edu	37	11	120957785	120957785	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	11	120957785	120957785	G	A	SNP	TBCEL	ENST00000422003	human	ensembl	74_37	1	known	missense	c.1255	p.V419M	1	pfscan_Ubiquitin_supergroup	pfscan_Ubiquitin_supergroup	0	no_errors	0	0	0	109	0	0	56	42	42.42	492	0	0.00	185	123	39.94
TMEM132D	0	genome.wustl.edu	37	12	130185157	130185157	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	12	130185157	130185157	C	T	SNP	TMEM132D	ENST00000422113	human	ensembl	74_37	-1	known	missense	c.166	p.A56T	0.992	NULL	NULL	0	no_errors	0	0	0	54	0	0	34	16	32	233	0	0.00	106	41	27.89
ITGBL1	0	genome.wustl.edu	37	13	102227854	102227854	+	Silent	SNP	C	C	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	13	102227854	102227854	C	T	SNP	ITGBL1	ENST00000376180	human	ensembl	74_37	1	known	silent	c.543	p.D181	0.997	NULL	pfam_EGF_extracell,smart_EG-like_dom	0	no_errors	0	0	0	198	0	0	76	59	43.7	286	2	0.69	127	73	36.32
SAFB2	0	genome.wustl.edu	37	19	5591761	5591761	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	19	5591761	5591761	G	C	SNP	SAFB2	ENST00000252542	human	ensembl	74_37	-1	known	missense	c.2392	p.Q798E	1	NULL	pfam_RRM_dom,pfam_SAP_dom,smart_SAP_dom,smart_RRM_dom,pfscan_SAP_dom,pfscan_RRM_dom	0	no_errors	0	0	0	47	0	0	24	26	52	122	0	0.00	56	39	41.05
DUS3L	0	genome.wustl.edu	37	19	5787673	5787673	+	Missense_Mutation	SNP	A	A	G			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	19	5787673	5787673	A	G	SNP	DUS3L	ENST00000309061	human	ensembl	74_37	-1	known	missense	c.1139	p.L380P	1	pfam_tRNA_hU_synthase	pfam_tRNA_hU_synthase	0	no_errors	0	0	0	17	0	0	17	8	32	185	0	0.00	62	21	25.30
ZNF569	0	genome.wustl.edu	37	19	37903959	37903959	+	Missense_Mutation	SNP	A	A	G			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	19	37903959	37903959	A	G	SNP	ZNF569	ENST00000316950	human	ensembl	74_37	-1	known	missense	c.1601	p.I534T	0	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	0	no_errors	0	0	0	98	0	0	39	24	38.1	257	0	0.00	109	74	40.22
ZNF574	0	genome.wustl.edu	37	19	42584756	42584756	+	Silent	SNP	C	C	G			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	19	42584756	42584756	C	G	SNP	ZNF574	ENST00000222339	human	ensembl	74_37	1	known	silent	c.2268	p.R756	0.999	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	0	no_errors	0	0	0	18	0	0	6	13	68.42	36	0	0.00	12	11	47.83
BACH1	0	genome.wustl.edu	37	21	30699208	30699208	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699208	30699208	G	A	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1063	p.D355N	0.008	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	35	0	0	25	24	48.98	480	0	0.00	188	270	58.95
BACH1	0	genome.wustl.edu	37	21	30699241	30699241	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699241	30699241	G	A	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1096	p.D366N	0.016	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	33	0	0	25	21	45.65	461	0	0.00	183	250	57.74
BACH1	0	genome.wustl.edu	37	21	30699274	30699274	+	Nonsense_Mutation	SNP	G	G	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699274	30699274	G	T	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	nonsense	c.1129	p.E377*	0.984	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	32	0	0	22	22	50	440	0	0.00	179	230	56.23
BACH1	0	genome.wustl.edu	37	21	30699313	30699313	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699313	30699313	G	C	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1168	p.E390Q	1	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	30	0	0	13	13	50	404	0	0.00	158	195	55.24
BACH1	0	genome.wustl.edu	37	21	30699589	30699589	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699589	30699589	G	C	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1444	p.D482H	0.073	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	79	0	0	30	37	55.22	457	0	0.00	181	216	54.41
BACH1	0	genome.wustl.edu	37	21	30699613	30699613	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699613	30699613	G	C	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1468	p.E490Q	0.996	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	64	0	0	30	32	51.61	487	0	0.00	191	214	52.58
BACH1	0	genome.wustl.edu	37	21	30699649	30699649	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699649	30699649	G	A	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1504	p.D502N	0.995	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	63	0	0	27	29	51.79	472	1	0.21	177	207	53.91
BACH1	0	genome.wustl.edu	37	21	30699664	30699664	+	Missense_Mutation	SNP	G	G	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699664	30699664	G	C	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1519	p.D507H	1	NULL	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	62	0	0	25	28	51.85	436	0	0.00	169	205	54.81
BACH1	0	genome.wustl.edu	37	21	30699682	30699682	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	30699682	30699682	G	A	SNP	BACH1	ENST00000286800	human	ensembl	74_37	1	known	missense	c.1537	p.E513K	1	superfamily_TF_DNA-bd	pfam_BTB_POZ,pfam_bZIP,superfamily_BTB/POZ_fold,superfamily_TF_DNA-bd,smart_BTB/POZ-like,smart_bZIP,pfscan_BTB/POZ-like,pfscan_bZIP	0	no_errors	0	0	0	62	0	0	22	32	59.26	415	1	0.24	159	208	56.52
PDE4B	0	genome.wustl.edu	37	1	66384467	66384468	+	Frame_Shift_Ins	INS	-	-	AA			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	-	-	-	AA	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	1	66384467	66384468	0	AA	INS	PDE4B	ENST00000329654	human	ensembl	74_37	1	known	frame_shift_ins	c.230_231	p.P78fs	0.973:0.964	NULL	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom,prints_PDEase	0	no_errors	0	0	0	51	0	0	42	9	17.65	277	0	0.00	163	17	9.44
DTX3L	0	genome.wustl.edu	37	3	122288784	122288791	+	Frame_Shift_Del	DEL	TTTCACTG	TTTCACTG	-			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	TTTCACTG	TTTCACTG	TTTCACTG	-	TTTCACTG	TTTCACTG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	3	122288784	122288791	TTTCACTG	0	DEL	DTX3L	ENST00000296161	human	ensembl	74_37	1	known	frame_shift_del	c.1848_1855	p.T618fs	0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000	NULL	smart_Znf_RING,pfscan_Znf_RING	0	no_errors	0	0	0	44	0	0	25	5	16.67	350	0	0.00	161	18	10.06
WHSC1	0	genome.wustl.edu	37	4	1980558	1980559	+	Frame_Shift_Ins	INS	-	-	C			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	-	-	-	C	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	4	1980558	1980559	0	C	INS	WHSC1	ENST00000382891	human	ensembl	74_37	1	known	frame_shift_ins	c.4020_4021	p.E1343fs	0.734:0.982	NULL	pfam_PWWP_dom,pfam_SET_dom,pfam_Znf_PHD-finger,pfam_HMG_box_dom,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_PWWP_dom,smart_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_AWS,smart_SET_dom,smart_Post-SET_dom,pfscan_AWS,pfscan_PWWP_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_RING,pfscan_HMG_box_dom	0	no_errors	0	0	0	19	0	0	12	6	33.33	112	2	1.75	47	27	36.49
MPHOSPH9	0	genome.wustl.edu	37	12	123706353	123706356	+	Frame_Shift_Del	DEL	TTGT	TTGT	-			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	TTGT	TTGT	TTGT	-	TTGT	TTGT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	12	123706353	123706356	TTGT	0	DEL	MPHOSPH9	ENST00000606320	human	ensembl	74_37	-1	novel	frame_shift_del	c.438_435	p.Q146fs	0.000:0.001:0.010:0.006	NULL	superfamily_Prefoldin	0	no_errors	0	0	0	74	0	0	38	21	35.59	452	0	0.00	213	97	31.29
ACSS1	0	genome.wustl.edu	37	20	25004221	25004231	+	Frame_Shift_Del	DEL	CCACCACGCGC	CCACCACGCGC	-			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	CCACCACGCGC	CCACCACGCGC	CCACCACGCGC	-	CCACCACGCGC	CCACCACGCGC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	20	25004221	25004231	CCACCACGCGC	0	DEL	ACSS1	ENST00000323482	human	ensembl	74_37	-1	known	frame_shift_del	c.688_678	p.R227fs	0.988:0.060:0.058:0.015:0.198:0.204:0.106:0.008:0.991:0.993:0.961	pfam_AMP-dep_Synth/Lig,tigrfam_Ac_CoA_lig	pfam_AMP-dep_Synth/Lig,tigrfam_Ac_CoA_lig	0	no_errors	0	0	0	38	0	0	42	4	8.7	161	0	0.00	73	15	17.05
KRTAP10-6	0	genome.wustl.edu	37	21	46011494	46011494	+	Missense_Mutation	SNP	G	G	T			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	21	46011494	46011494	G	T	SNP	KRTAP10-6	ENST00000400368	human	ensembl	74_37	-1	known	missense	c.872	p.A291D	0	NULL	NULL	0	no_errors	0	0	0	67	0	0	37	3	7.5	10	0	0.00	5	0	0.00
RPL29	0	genome.wustl.edu	37	3	52028090	52028090	+	Frame_Shift_Del	DEL	T	T	-			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	3	52028090	52028090	T	0	DEL	RPL29	ENST00000294189	human	ensembl	74_37	-1	known	frame_shift_del	c.155	p.K52fs	1	NULL	pfam_Ribosomal_L29e	0	no_errors	0	0	0	77	0	0	39	3	7.14	5	0	0.00	4	0	0.00
ATRN	0	genome.wustl.edu	37	20	3452004	3452006	+	In_Frame_Del	DEL	GCG	GCG	-			TCGA-ZB-A969-01A-11D-A428-09	TCGA-ZB-A969-11A-11D-A42B-09	GCG	GCG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f5d0ee62-548f-47f5-a81f-08283357a321	96120df2-4b62-4a53-abbb-2b7564156339	20	3452004	3452006	GCG	0	DEL	ATRN	ENST00000262919	human	ensembl	74_37	1	known	in_frame_del	c.250_252	p.A87in_frame_del	1.000:1.000:1.000	NULL	pfam_Kelch_1,pfam_Plexin_repeat,pfam_CUB_dom,superfamily_C-type_lectin_fold,superfamily_CUB_dom,superfamily_Plexin-like_fold,smart_EG-like_dom,smart_CUB_dom,smart_Plexin-like_fold,smart_C-type_lectin,smart_EGF_laminin,pfscan_CUB_dom,pfscan_EG-like_dom,pfscan_EGF_laminin,pfscan_C-type_lectin	0	no_errors	0	0	0	10	0	0	6	2	25	11	0	0.00	4	0	0.00