Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
MT-ND5	0	genome.wustl.edu	37	MT	14133	14133	+	Silent	SNP	A	A	C			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	MT	14133	14133	A	C	SNP	MT-ND5	ENST00000361567	human	ensembl	74_37	1	known	silent	c.1797	p.L599	NULL	pfam_NADH_DH_su5_C	pfam_NADH_UbQ/plastoQ_OxRdtase,pfam_NADH_DH_su5_C,pfam_NADH_UbQ_OxRdtase_chain5/L_N,tigrfam_NADHpl_OxRdtase_5	0	no_errors	0	0	0	9	0	0	9	19	67.86	4	0	0.00	0	3	100.00
SLC38A5	0	genome.wustl.edu	37	X	48326271	48326271	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	X	48326271	48326271	G	A	SNP	SLC38A5	ENST00000317669	human	ensembl	74_37	-1	known	missense	c.41	p.S14L	0.013	NULL	pfam_AA_transpt_TM	0	no_errors	0	0	0	46	0	0	66	13	16.46	81	0	0.00	100	42	29.58
OR14I1	0	genome.wustl.edu	37	1	248844765	248844765	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	1	248844765	248844765	G	A	SNP	OR14I1	ENST00000342623	human	ensembl	74_37	-1	known	missense	c.841	p.P281S	0.968	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_Olfact_rcpt	0	no_errors	0	0	0	56	0	0	44	8	15.38	213	0	0.00	232	44	15.88
SF3B1	0	genome.wustl.edu	37	2	198266834	198266834	+	Missense_Mutation	SNP	T	T	C			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	2	198266834	198266834	T	C	SNP	SF3B1	ENST00000335508	human	ensembl	74_37	-1	known	missense	c.2098	p.K700E	1	superfamily_ARM-type_fold	pfam_SF3b_su1,superfamily_ARM-type_fold	0	no_errors	rs559063155	T->C	0	41	0	0	38	10	20.83	167	0	0.00	248	33	11.70
PBRM1	0	genome.wustl.edu	37	3	52620451	52620451	+	Missense_Mutation	SNP	T	T	C			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	3	52620451	52620451	T	C	SNP	PBRM1	ENST00000296302	human	ensembl	74_37	-1	known	missense	c.3377	p.N1126S	0.843	NULL	pfam_Bromodomain,pfam_BAH_dom,pfam_HMG_box_dom,superfamily_Bromodomain,superfamily_HMG_box_dom,smart_Bromodomain,smart_BAH_dom,smart_HMG_box_dom,pfscan_BAH_dom,pfscan_HMG_box_dom,pfscan_Bromodomain,prints_Bromodomain	0	no_errors	0	0	0	42	0	0	45	5	10	225	0	0.00	216	34	13.60
TACC1	0	genome.wustl.edu	37	8	38677775	38677775	+	Missense_Mutation	SNP	C	C	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	8	38677775	38677775	C	A	SNP	TACC1	ENST00000379931	human	ensembl	74_37	1	known	missense	c.1013	p.P338Q	0.998	NULL	pfam_TACC	0	no_errors	0	0	0	42	0	0	66	7	9.46	129	2	1.53	166	11	6.21
TONSL	0	genome.wustl.edu	37	8	145663936	145663936	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	8	145663936	145663936	C	T	SNP	TONSL	ENST00000409379	human	ensembl	74_37	-1	known	missense	c.1571	p.R524Q	0.998	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_TPR_repeat,smart_Ankyrin_rpt,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_TPR-contain_dom,prints_Ankyrin_rpt	0	no_errors	0	0	0	60	1	1.64	56	10	15.15	74	0	0.00	78	9	10.34
C9orf43	0	genome.wustl.edu	37	9	116183409	116183409	+	Silent	SNP	G	G	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	9	116183409	116183409	G	A	SNP	C9orf43	ENST00000288462	human	ensembl	74_37	1	known	silent	c.372	p.T124	0.093	NULL	NULL	0	no_errors	rs372647158	G->A	0.9998,0.0001997	21	0	0	24	3	11.11	189	0	0.00	278	16	5.44
RIMBP2	0	genome.wustl.edu	37	12	130935797	130935797	+	Silent	SNP	G	G	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	12	130935797	130935797	G	A	SNP	RIMBP2	ENST00000261655	human	ensembl	74_37	-1	known	silent	c.396	p.S132	0.928	NULL	pfam_SH3_2,pfam_SH3_domain,superfamily_SH3_domain,superfamily_Fibronectin_type3,smart_SH3_domain,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_SH3_domain,prints_SH3_domain	0	no_errors	0	0	0	59	0	0	50	10	16.67	59	0	0.00	43	11	20.37
BRCA2	0	genome.wustl.edu	37	13	32921032	32921032	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	13	32921032	32921032	C	T	SNP	BRCA2	ENST00000380152	human	ensembl	74_37	1	known	missense	c.7006	p.R2336C	0.118	pirsf_BRCA2	pfam_DNA_recomb/repair_BRCA2_hlx,pfam_BRCA2_repeat,pfam_BRCA2_OB_3,pfam_BRCA2_OB_1,pfam_Tower,superfamily_DNA_recomb/repair_BRCA2_hlx,superfamily_NA-bd_OB-fold,pirsf_BRCA2,pfscan_BRCA2_repeat	0	no_errors	rs431825347	C->G,T	0	73	0	0	80	13	13.98	270	1	0.37	336	61	15.33
ARID3B	0	genome.wustl.edu	37	15	74883596	74883596	+	Missense_Mutation	SNP	C	C	G			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	15	74883596	74883596	C	G	SNP	ARID3B	ENST00000346246	human	ensembl	74_37	1	known	missense	c.986	p.P329R	1	NULL	pfam_ARID/BRIGHT_DNA-bd,superfamily_ARID/BRIGHT_DNA-bd,smart_ARID/BRIGHT_DNA-bd,pfscan_ARID/BRIGHT_DNA-bd	0	no_errors	0	0	0	56	0	0	45	9	16.67	61	1	1.59	66	10	13.16
WDR90	0	genome.wustl.edu	37	16	712780	712780	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	16	712780	712780	C	T	SNP	WDR90	ENST00000549091	human	ensembl	74_37	1	novel	missense	c.4253	p.T1418M	0.998	superfamily_Quinonprotein_ADH-like_supfam,superfamily_WD40_repeat_dom,pfscan_WD40_repeat_dom	pfam_WD40_repeat,pfam_DUF667,pfam_Nucleoporin_Nup160,superfamily_Quinonprotein_ADH-like_supfam,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	0	no_errors	rs576866547	C->T	0.9996,0.0003994	19	0	0	28	3	9.68	58	0	0.00	62	6	8.82
SLC12A3	0	genome.wustl.edu	37	16	56918063	56918063	+	Missense_Mutation	SNP	T	T	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	16	56918063	56918063	T	A	SNP	SLC12A3	ENST00000438926	human	ensembl	74_37	1	known	missense	c.1772	p.I591N	1	pfam_AA-permease/SLC12A_dom,tigrfam_Na/K/Cl_cotransptS	pfam_AA-permease/SLC12A_dom,pfam_AA_permease_N,prints_NaCl_cotranspt,tigrfam_Na/K/Cl_cotransptS	0	no_errors	0	0	0	24	0	0	22	4	15.38	119	0	0.00	108	29	21.17
JPH3	0	genome.wustl.edu	37	16	87723875	87723875	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	16	87723875	87723875	C	T	SNP	JPH3	ENST00000284262	human	ensembl	74_37	1	known	missense	c.1909	p.R637W	1	pirsf_Junctophilin	pirsf_Junctophilin,pfam_MORN,smart_MORN	0	no_errors	0	0	0	67	0	0	55	10	15.38	53	1	1.85	54	7	11.48
NPLOC4	0	genome.wustl.edu	37	17	79596825	79596825	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	17	79596825	79596825	G	A	SNP	NPLOC4	ENST00000374747	human	ensembl	74_37	-1	known	missense	c.22	p.R8C	1	pfam_Npl4_Ub-like_dom,pirsf_PolyUb_recognition_cplx_Npl4	pfam_NPL4,pfam_NPL4_Zn-bd_put,pfam_Npl4_Ub-like_dom,pirsf_PolyUb_recognition_cplx_Npl4	0	no_errors	0	0	0	43	0	0	13	4	23.53	165	0	0.00	245	27	9.93
SPTBN4	0	genome.wustl.edu	37	19	41029463	41029463	+	Silent	SNP	C	C	G			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	19	41029463	41029463	C	G	SNP	SPTBN4	ENST00000352632	human	ensembl	74_37	1	known	silent	c.3774	p.A1258	0.997	pirsf_Spectrin_bsu,smart_Spectrin/alpha-actinin	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	0	no_errors	0	0	0	27	0	0	31	9	22.5	91	0	0.00	70	15	17.65
TTLL10-AS1	0	genome.wustl.edu	37	1	1111234	1111235	+	RNA	INS	-	-	GA			TCGA-ZB-A96F-01A-11D-A428-09	TCGA-ZB-A96F-10A-01D-A42B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1666b51d-314f-40e3-8371-fdc786f182bd	bd86ad4c-7124-4c89-96f1-a9542615b78f	1	1111234	1111235	0	GA	INS	TTLL10-AS1	ENST00000379317	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.928:0.920	0	0	0	no_errors	0	0	0	52	1	1.89	26	4	13.33	6	0	0.00	10	0	0.00