Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain DMAP1 55929 genome.wustl.edu 37 1 44685982 44685983 + Splice_Site INS - - T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001034023.1 +1 reviewed e9+1 1.000:1.000 - - - - - - - - - - ZZZ3 26009 genome.wustl.edu 37 1 78047468 78047468 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_015534.4 -1 provisional p.R634H 0.996 109 0% 40 45% 3 0% benign(0.152) tolerated(0.08) neutral(0.314) NULL TRAPPC12 51112 genome.wustl.edu 37 2 3469478 3469478 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000416918 +1 known p.T12M 0.000 58 0% 73 37% 0 - probably_damaging(0.995) deleterious(0) deleterious(0.902) superfamily_TPR-like SOS1 6654 genome.wustl.edu 37 2 39281778 39281778 + Missense_Mutation SNP T T A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_005633.3 -1 reviewed p.N233Y 1.000 72 0% 44 40.9% 0 - possibly_damaging(0.647) tolerated(0.27) neutral(0.261) HMMPfam_RhoGEF,HMMSmart_SM00325,superfamily_DBL homology domain (DH-domain) ATP6V1B1 525 genome.wustl.edu 37 2 71190370 71190370 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001692.3 +1 reviewed p.E330K 1.000 61 0% 76 34.2% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_ATP-synt_ab,superfamily_SSF52540 ZEB2 9839 genome.wustl.edu 37 2 145158777 145158777 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_014795.3 -1 reviewed p.R302Q 1.000 201 0% 57 43.9% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 LY75 4065 genome.wustl.edu 37 2 160688179 160688274 + Splice_Site DEL CTATGGCTTGATAATTATGTTATAATGAAGTACAAAAACAAATAGAGAAAGTTGGCAGATTTACAACTTACTTCTATAAGTTATTCCTAACATGAC CTATGGCTTGATAATTATGTTATAATGAAGTACAAAAACAAATAGAGAAAGTTGGCAGATTTACAACTTACTTCTATAAGTTATTCCTAACATGAC - novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 CTATGGCTTGATAATTATGTTATAATGAAGTACAAAAACAAATAGAGAAAGTTGGCAGATTTACAACTTACTTCTATAAGTTATTCCTAACATGAC CTATGGCTTGATAATTATGTTATAATGAAGTACAAAAACAAATAGAGAAAGTTGGCAGATTTACAACTTACTTCTATAAGTTATTCCTAACATGAC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_002349.2 -1 validated e29-1 1.000:1.000:0.903:0.937:0.967:0.988:0.995:1.000:1.000:0.989:0.972:0.960:0.909:0.896:0.072:0.069:0.928:0.931:0.544:0.545:0.149:0.004:0.003:0.003:0.099:0.984:0.999 - - - - - - - - - - PDE11A 50940 genome.wustl.edu 37 2 178685017 178685017 + Silent SNP G G A rs111708910 TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000433879 -1 known p.T141I 0.998 140 0% 52 48.1% 0 - - - - HMMPfam_GAF,HMMSmart_SM00065,superfamily_GAF domain-like TTN 7273 genome.wustl.edu 37 2 179664276 179664276 + Silent SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_133379.3 -1 reviewed p.S284 0.001 186 0% 76 30.3% 0 - - - - NULL CTNNB1 1499 genome.wustl.edu 37 3 41266101 41266101 + Missense_Mutation SNP C C G rs121913400 byCluster TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001098209.1 +1 reviewed p.S33C 1.000 121 0% 36 55.6% 31 48.3% probably_damaging(1) deleterious(0) deleterious(0.945) NULL ZNF445 353274 genome.wustl.edu 37 3 44489027 44489027 + Silent SNP G G A rs112610581 byCluster;byFrequency;by1000genomes TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_181489.5 -1 validated p.S712 0.000 106 0% 43 39.5% 0 - - - - HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 LOC100287439 100287439 genome.wustl.edu 37 3 48454127 48454127 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 XM_002342333.1 +1 model p.P12S 0.000 40 0% 37 56.8% 0 - - - - NULL LAMB2 3913 genome.wustl.edu 37 3 49159641 49159641 + Missense_Mutation SNP T T C novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_002292.3 -1 reviewed p.D1579G 1.000 62 0% 78 42.3% 141 29% possibly_damaging(0.887) deleterious(0.02) deleterious(0.730) NULL GNAI2 2771 genome.wustl.edu 37 3 50294369 50294369 + Missense_Mutation SNP A A C novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_002070.2 +1 reviewed p.N242H 1.000 165 0% 232 49.1% 264 35.9% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_G-alpha,HMMSmart_SM00275,superfamily_P-loop containing nucleoside triphosphate hydrolases DOCK3 1795 genome.wustl.edu 37 3 51393634 51393634 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_004947.3 +1 validated p.R1455Q 1.000 135 0% 49 36.7% 0 - probably_damaging(0.997) tolerated(0.83) neutral(0.467) HMMPfam_Ded_cyto GYG1 2992 genome.wustl.edu 37 3 148744654 148744654 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000484197 +1 known p.R239K 1.000 139 0% 60 53.3% 42 52.3% benign(0.202) tolerated(0.28) neutral(0.051) NULL HGFAC 3083 genome.wustl.edu 37 4 3451126 3451126 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001528.2 +1 reviewed p.R650W 0.024 40 0% 58 53.4% 4 50% probably_damaging(1) deleterious(0) deleterious(0.945) NULL IRX1 79192 genome.wustl.edu 37 5 3599697 3599697 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_024337.3 +1 validated p.G212D 1.000 98 0% 222 41.9% 0 - probably_damaging(1) tolerated(0.45) deleterious(0.512) NULL PIK3R1 5295 genome.wustl.edu 37 5 67589585 67589587 + In_Frame_Del DEL CAT CAT - novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 CAT CAT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_181523.1 +1 reviewed p.H450in_frame_del 1.000:1.000:1.000 - - - - - - - - - NULL PCDHA2 56146 genome.wustl.edu 37 5 140174682 140174682 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_018905.2 +1 reviewed p.V45M 1.000 57 0% 90 53.3% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00112,HMMPfam_Cadherin_2,superfamily_Cadherin-like KIAA0408 9729 genome.wustl.edu 37 6 127767965 127767965 + Missense_Mutation SNP T T C novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_014702.4 -1 validated p.H500R 0.000 269 0% 84 31% 0 - benign(0.198) tolerated(0.62) neutral(0.023) NULL HIBADH 11112 genome.wustl.edu 37 7 27582591 27582591 + Missense_Mutation SNP C C G novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_152740.2 -1 validated p.G205R 1.000 155 0% 50 40% 19 42.1% probably_damaging(0.99) deleterious(0) deleterious(0.886) superfamily_6-phosphogluconate dehydrogenase C-terminal domain-like,superfamily_NAD(P)-binding Rossmann-fold domains PLXNA4 91584 genome.wustl.edu 37 7 131912350 131912350 + Frame_Shift_Del DEL G G - novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_020911.1 -1 validated p.T581fs 1.000 - - - - - - - - - NULL C8orf42 157695 genome.wustl.edu 37 8 494659 494664 + In_Frame_Del DEL GGCGGC GGCGGC - rs150473269 by1000genomes TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 GGCGGC GGCGGC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_175075.3 -1 validated p.AA32in_frame_del 0.066:0.068:0.048:0.038:0.021:0.012 - - - - - - - - - NULL TMEM74 157753 genome.wustl.edu 37 8 109796608 109796608 + Silent SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_153015.1 -1 provisional p.T240 0.274 118 0% 188 12.8% 0 - - - - NULL PCSK5 5125 genome.wustl.edu 37 9 78686658 78686658 + Silent SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_006200.3 +1 reviewed p.D246 0.999 109 0.9% 115 40% 1 0% - - - HMMPfam_Peptidase_S8,superfamily_Subtilisin-like PTEN 5728 genome.wustl.edu 37 10 89717749 89717749 + Frame_Shift_Del DEL C C - novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000371953 +1 known p.H259fs 1.000 - - - - - - - - - superfamily_C2 domain (Calcium/lipid-binding domain CaLB),HMMPfam_PTEN_C2 PTEN 5728 genome.wustl.edu 37 10 89720799 89720802 + Frame_Shift_Del DEL TACT TACT - novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 TACT TACT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000371953 +1 known p.T319fs 1.000:1.000:1.000:1.000 - - - - - - - - - superfamily_C2 domain (Calcium/lipid-binding domain CaLB),HMMPfam_PTEN_C2 PKD2L1 9033 genome.wustl.edu 37 10 102056841 102056841 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_016112.2 -1 reviewed p.V361I 0.011 200 0% 170 31.8% 0 - benign(0.002) tolerated(1) - HMMPfam_PKD_channel,superfamily_Voltage-gated potassium channels SLC25A22 79751 genome.wustl.edu 37 11 792389 792389 + Silent SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_024698.4 -1 provisional p.S219 0.000 53 0% 102 40.2% 15 40% - - - superfamily_Mitoch_carrier,HMMPfam_Mito_carr SLCO1B3 28234 genome.wustl.edu 37 12 21051410 21051410 + Nonsense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_019844.2 +1 validated p.Q575* 0.330 194 0% 87 40.2% 0 - - - - HMMPfam_OATP,superfamily_MFS_gen_substrate_transporter DTX1 1840 genome.wustl.edu 37 12 113515475 113515475 + Missense_Mutation SNP T T C novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_004416.2 +1 reviewed p.L169P 1.000 24 0% 40 37.5% 1 100% possibly_damaging(0.926) deleterious(0) deleterious(0.819) HMMPfam_WWE,HMMSmart_WWE KIAA0564 23078 genome.wustl.edu 37 13 42361623 42361623 + Missense_Mutation SNP A A G novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_015058.1 -1 validated p.I707T 1.000 155 0% 71 47.9% 0 - possibly_damaging(0.95) deleterious(0.02) deleterious(0.776) superfamily_P-loop containing nucleoside triphosphate hydrolases SYT16 83851 genome.wustl.edu 37 14 62550928 62550928 + Silent SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_031914.2 +1 validated p.P483 1.000 156 0% 146 43.8% 0 - - - - NULL TSC2 7249 genome.wustl.edu 37 16 2134536 2134536 + Missense_Mutation SNP G G A rs45448791 TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_000548.3 +1 reviewed p.R1438Q 0.004 28 0% 44 47.7% 44 43.1% benign(0.001) tolerated(0.22) neutral(0.042) NULL XYLT1 64131 genome.wustl.edu 37 16 17211800 17211800 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_022166.3 -1 reviewed p.R754C 1.000 143 0% 54 31.5% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) NULL NDRG4 65009 genome.wustl.edu 37 16 58537768 58537768 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001130487.1 +1 reviewed p.R82C 1.000 89 0% 93 43% 4 25% probably_damaging(0.992) deleterious(0) deleterious(0.892) HMMPfam_Ndr,superfamily_SSF53474 CTCF 10664 genome.wustl.edu 37 16 67654646 67654646 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_006565.2 +1 reviewed p.P378L 1.000 116 0% 31 45.2% 8 37.5% probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_C2H2 and C2HC zinc fingers SGSM2 9905 genome.wustl.edu 37 17 2266367 2266367 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_014853.2 +1 validated p.R204Q 1.000 40 0% 47 21.3% 4 25% probably_damaging(1) deleterious(0.03) deleterious(0.865) NULL ST6GALNAC2 10610 genome.wustl.edu 37 17 74570581 74570581 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_006456.2 -1 validated p.R76Q 0.000 31 0% 48 35.4% 2 100% benign(0.032) tolerated(0.13) neutral(0.254) HMMPfam_Glyco_transf_29 CCDC137 339230 genome.wustl.edu 37 17 79638795 79638796 + Frame_Shift_Ins INS - - A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_199287.2 +1 validated p.V174fs 0.058:0.063 - - - - - - - - - NULL DNMT1 1786 genome.wustl.edu 37 19 10246949 10246949 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001130823.1 -1 reviewed p.D1502N 1.000 105 0% 71 39.4% 76 55.2% benign(0.349) deleterious(0.01) deleterious(0.516) superfamily_S-adenosyl-L-methionine-dependent methyltransferases SIPA1L3 23094 genome.wustl.edu 37 19 38621291 38621291 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_015073.1 +1 validated p.V1008M 1.000 39 0% 46 39.1% 2 50% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_PDZ,HMMSmart_PDZ,superfamily_PDZ ZNF628 89887 genome.wustl.edu 37 19 55994492 55994492 + Silent SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_033113.2 +1 validated p.H640 0.559 19 0% 40 15% 6 16.6% - - - HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers ZNF334 55713 genome.wustl.edu 37 20 45131473 45131473 + Missense_Mutation SNP C C A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_018102.3 -1 validated p.G169W 0.007 286 0% 249 42.6% 0 - probably_damaging(0.998) deleterious(0.03) deleterious(0.839) NULL LOC100288017 100288017 genome.wustl.edu 37 21 14568450 14568450 + Frame_Shift_Del DEL T T - novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 XM_002343737.1 +1 model p.L28fs 0.011 - - - - - - - - - NULL ENSG00000182490 0 genome.wustl.edu 37 22 19119752 19119752 + Missense_Mutation SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000383058 -1 known p.R81C 0.971 38 0% 30 43.3% 0 - - - - NULL ENSG00000210082 0 genome.wustl.edu 37 MT 2831 2831 + RNA SNP G G A novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 ENST00000387347 +1 known NULL NULL 13 0% 27 40.7% 3756 38.4% - - - - DDX3X 1654 genome.wustl.edu 37 X 41206199 41206199 + Missense_Mutation SNP C C T novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_001356.3 +1 reviewed p.P568L 1.000 217 0% 117 43.6% 31 70.9% probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_P-loop containing nucleoside triphosphate hydrolases FAAH2 158584 genome.wustl.edu 37 X 57475070 57475070 + Missense_Mutation SNP G G C novel TCGA-A5-A0R9-01A-11D-A10B-09 TCGA-A5-A0R9-10A-01D-A10B-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 25cca3d0-a103-42dd-8be0-5eb40b07c0ae ebb7e2b0-7b52-4694-8ca2-2c3d55cf9576 NM_174912.3 +1 reviewed p.V448L 0.161 271 0% 43 41.9% 31 0% possibly_damaging(0.812) deleterious(0.01) deleterious(0.711) HMMPfam_Amidase,superfamily_Amidase signature (AS) enzymes