Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain SRSF4 6429 genome.wustl.edu 37 1 29476622 29476622 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_005626.4 -1 reviewed p.R221W 1.000 185 0% 158 36.7% 49 42.8% unknown(0) deleterious(0) - NULL INADL 10207 genome.wustl.edu 37 1 62234986 62234986 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_176877.2 +1 reviewed p.R139Q 0.999 125 0% 128 43% 5 60% possibly_damaging(0.934) deleterious(0.02) deleterious(0.763) HMMPfam_PDZ,superfamily_PDZ domain-like EXO1 9156 genome.wustl.edu 37 1 242015642 242015642 + Silent SNP G G T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_006027.4 +1 reviewed p.G70 0.232 93 0% 84 41.7% 1 100% - - - HMMPfam_XPG_N,HMMSmart_SM00485,superfamily_PIN domain-like OR2T2 401992 genome.wustl.edu 37 1 248616705 248616711 + Frame_Shift_Del DEL TGCTGCG TGCTGCG - rs35380868 TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 TGCTGCG TGCTGCG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001004136.1 +1 provisional p.C204fs 0.000:0.001:0.000:0.000:0.000:0.000:0.001 - - - - - - - - - HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like INPP4A 3631 genome.wustl.edu 37 2 99155410 99155410 + Frame_Shift_Del DEL C C - novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001134224.1 +1 reviewed p.Y212fs 1.000 - - - - - - - - - NULL STK11IP 114790 genome.wustl.edu 37 2 220472928 220472928 + Frame_Shift_Del DEL C C - novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be ENST00000456909 +1 known p.Q461fs 0.000 - - - - - - - - - NULL CTNNB1 1499 genome.wustl.edu 37 3 41266097 41266097 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001098209.1 +1 reviewed p.D32N 1.000 93 0% 85 40% 134 36.5% probably_damaging(1) deleterious(0) deleterious(0.945) NULL PCCB 5096 genome.wustl.edu 37 3 136048867 136048867 + Nonstop_Mutation SNP A A C novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_000532.4 +1 reviewed p.*540S 0.981 172 0% 202 41.1% 34 50% - - - NULL PIK3R1 5295 genome.wustl.edu 37 5 67589606 67589623 + In_Frame_Del DEL CAAGAAAAAAGTCGAGAA CAAGAAAAAAGTCGAGAA - novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 CAAGAAAAAAGTCGAGAA CAAGAAAAAAGTCGAGAA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_181523.1 +1 reviewed p.QEKSRE457in_frame_del 1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.999:0.929:0.484:0.483:0.234:1.000:1.000:1.000 - - - - - - - - - NULL PCDHB3 56132 genome.wustl.edu 37 5 140481691 140481691 + Silent SNP A A C novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_018937.2 +1 reviewed p.V486 0.258 144 0% 123 46.3% 3 100% - - - HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like OR2V2 285659 genome.wustl.edu 37 5 180582876 180582876 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_206880.1 +1 provisional p.G312S 0.014 46 0% 37 43.2% 0 - possibly_damaging(0.638) tolerated(0.2) neutral(0.273) NULL PTPRK 5796 genome.wustl.edu 37 6 128718765 128718765 + Missense_Mutation SNP A A C novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001135648.1 -1 validated p.W57G 0.999 345 0% 292 41.8% 18 38.8% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_MAM,HMMSmart_MAM IL7 3574 genome.wustl.edu 37 8 79710386 79710386 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_000880.2 -1 reviewed p.A23V 0.999 237 0% 180 41.7% 0 - benign(0.227) deleterious(0.03) neutral(0.387) NULL EXT1 2131 genome.wustl.edu 37 8 118847713 118847713 + Silent SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be ENST00000436216 -1 known p.R168C 1.000 150 0% 107 14% 12 25% - - - HMMPfam_Exostosin LOC100288108 100288108 genome.wustl.edu 37 8 140631011 140631011 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be XM_002342878.1 +1 model p.V252I 0.999 78 0% 51 47.1% 0 - - - - NULL KDM4C 23081 genome.wustl.edu 37 9 7174666 7174666 + Silent SNP C C T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_015061.3 +1 reviewed p.A1036 0.999 337 0% 226 45.1% 8 37.5% - - - NULL TAF1L 138474 genome.wustl.edu 37 9 32631370 32631370 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_153809.2 -1 provisional p.T1403M 0.984 619 0% 444 46.8% 0 - probably_damaging(1) deleterious(0.02) deleterious(0.883) HMMSmart_BROMO,superfamily_Bromodomain PTEN 5728 genome.wustl.edu 37 10 89685314 89685315 + Frame_Shift_Del DEL TG TG - rs121909226 TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 TG TG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be ENST00000371953 +1 known p.C71fs 1.000 - - - - - - - - - HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II PTEN 5728 genome.wustl.edu 37 10 89692904 89692904 + Missense_Mutation SNP C C G rs121909224 byCluster TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be ENST00000371953 +1 known p.R130G 1.000 348 0% 491 30.5% 80 25% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_DSPc,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II PGAP2 27315 genome.wustl.edu 37 11 3846853 3846855 + RNA DEL CTC CTC - rs3217617 byCluster;by1000genomes TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 CTC CTC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NR_027014.1 +1 validated NULL 0.231:0.226:0.001 - - - - - - - - - - FAT3 120114 genome.wustl.edu 37 11 92498155 92498155 + Silent SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001008781.2 +1 validated p.P1365 0.009 102 0% 115 47% 0 - - - - superfamily_Concanavalin A-like lectins/glucanases,superfamily_Cadherin-like CADM1 23705 genome.wustl.edu 37 11 115109307 115109307 + Missense_Mutation SNP T T C novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_014333.3 -1 validated p.N113D 1.000 122 0% 118 33.9% 71 43.6% probably_damaging(0.999) tolerated(0.84) deleterious(0.491) HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_V-set,superfamily_Immunoglobulin RERG 85004 genome.wustl.edu 37 12 15262109 15262109 + Nonsense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_032918.1 -1 provisional p.R179* 1.000 274 0% 110 51.8% 1 0% - - - superfamily_P-loop containing nucleoside triphosphate hydrolases COL4A1 1282 genome.wustl.edu 37 13 110864923 110864923 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001845.4 -1 reviewed p.P108S 1.000 108 0% 110 39.1% 20 5% unknown(0) tolerated(0.45) - HMMPfam_Collagen RNASE7 84659 genome.wustl.edu 37 14 21511572 21511572 + Missense_Mutation SNP G G T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_032572.3 +1 validated p.D141Y 0.002 562 0% 370 42.4% 0 - benign(0.055) deleterious(0) neutral(0.448) HMMPfam_RnaseA,HMMSmart_SM00092,superfamily_RNase A-like SLC8A3 6547 genome.wustl.edu 37 14 70634329 70634329 + Nonsense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_183002.1 -1 reviewed p.R271* 1.000 153 0.7% 130 40.8% 0 - - - - NULL GREM1 26585 genome.wustl.edu 37 15 33023162 33023162 + Nonsense_Mutation SNP C C T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_013372.5 +1 reviewed p.R91* 1.000 151 0% 32 46.9% 1 0% - - - HMMPfam_DAN PIGQ 9091 genome.wustl.edu 37 16 633130 633130 + Silent SNP T T C novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_148920.1 +1 reviewed p.A593 0.001 3 0.000 16 0.562 64 40.6% - - - NULL CYB5B 80777 genome.wustl.edu 37 16 69496358 69496358 + Missense_Mutation SNP A A G novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_030579.2 +1 validated p.I130V 0.998 94 0% 55 78.2% 98 95.9% benign(0.002) tolerated(0.72) neutral(0.002) NULL OR3A3 8392 genome.wustl.edu 37 17 3324433 3324433 + Missense_Mutation SNP C C A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_012373.2 +1 validated p.P191Q 0.585 287 0% 219 37.4% 0 - probably_damaging(0.988) tolerated(0.18) deleterious(0.493) HMMPfam_7tm_1,superfamily_SSF81321 TRPV3 162514 genome.wustl.edu 37 17 3436191 3436191 + Silent SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_145068.2 -1 reviewed p.P275 0.181 29 0% 25 40% 0 - - - - HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat KANSL1 284058 genome.wustl.edu 37 17 44249046 44249068 + Frame_Shift_Del DEL TTTACAGGTGCTTGTGGCAGAGC TTTACAGGTGCTTGTGGCAGAGC - novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 TTTACAGGTGCTTGTGGCAGAGC TTTACAGGTGCTTGTGGCAGAGC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_015443.2 -1 validated p.A148fs 1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.999:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000 - - - - - - - - - NULL ZNF700 90592 genome.wustl.edu 37 19 12059258 12059258 + Missense_Mutation SNP C C A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_144566.1 +1 provisional p.S140Y 0.012 178 0% 223 46.2% 2 100% probably_damaging(0.999) tolerated(0.06) deleterious(0.813) NULL NFKBIB 4793 genome.wustl.edu 37 19 39397877 39397877 + Silent SNP C C T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_002503.3 +1 validated p.H212 0.737 46 0% 30 46.7% 21 28.5% - - - HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat ARHGAP35 2909 genome.wustl.edu 37 19 47440623 47440623 + Missense_Mutation SNP C C A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_004491.4 +1 reviewed p.P1262T 1.000 211 0% 204 39.2% 16 37.5% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_RhoGAP,HMMSmart_SM00324,superfamily_GTPase activation domain GAP NCAM2 4685 genome.wustl.edu 37 21 22658642 22658642 + Missense_Mutation SNP G G C novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_004540.2 +1 reviewed p.D131H 0.872 64 0% 63 52.4% 0 - benign(0.343) deleterious(0.01) deleterious(0.514) HMMSmart_IGc2,HMMPfam_ig,superfamily_SSF48726 C22orf13 83606 genome.wustl.edu 37 22 24942937 24942937 + Missense_Mutation SNP G G A rs191716304 by1000genomes TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_031444.2 -1 validated p.R111W 1.000 66 0% 60 13.3% 26 23% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Guanylate_cyc_2 FOXP3 50943 genome.wustl.edu 37 X 49107964 49107964 + Missense_Mutation SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be ENST00000455775 -1 known p.P401L 0.001 19 0% 13 46.2% 0 - unknown(0) - - HMMPfam_Fork_head,HMMSmart_FH P2RY10 27334 genome.wustl.edu 37 X 78216335 78216335 + Silent SNP C C T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_014499.2 +1 reviewed p.C106 1.000 635 0.2% 584 46.1% 0 - - - - HMMPfam_7tm_1,superfamily_SSF81321 GUCY2F 2986 genome.wustl.edu 37 X 108652309 108652309 + Missense_Mutation SNP G G T novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001522.2 -1 reviewed p.S627Y 0.964 409 0.2% 310 11.3% 0 - probably_damaging(0.995) deleterious(0.01) deleterious(0.863) HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like) CT47B1 643311 genome.wustl.edu 37 X 120007855 120007855 + Silent SNP G G A novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_001145718.1 -1 validated p.P265 0.001 448 0.4% 338 40.8% 0 - - - - NULL ZNF75D 7626 genome.wustl.edu 37 X 134424989 134424989 + Missense_Mutation SNP T T G novel TCGA-AX-A05U-01A-11W-A027-09 TCGA-AX-A05U-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 705d3931-f13a-4e0f-a2d8-21f36aab2107 c9371786-a86f-46aa-9b4b-5b39016f33be NM_007131.3 -1 reviewed p.K257Q 0.869 457 0% 350 40% 0 - possibly_damaging(0.952) tolerated(0.17) neutral(0.455) HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box