Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain MTOR 2475 genome.wustl.edu 37 1 11269454 11269454 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_004958.3 -1 reviewed p.S1239N 0.998 543 0% 463 61.8% 3 33.3% benign(0.006) tolerated(0.49) neutral(0.011) superfamily_ARM-type_fold SRRM1 10250 genome.wustl.edu 37 1 24998048 24998048 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_005839.3 +1 validated p.A858T 1.000 127 0% 81 53.1% 1 0% unknown(0) deleterious(0) - NULL AGL 178 genome.wustl.edu 37 1 100350142 100350142 + Missense_Mutation SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_000028.2 +1 reviewed p.H855R 0.995 131 0% 95 28.4% 1 0% benign(0.025) tolerated(0.44) neutral(0.014) NULL ENSG00000207321 0 genome.wustl.edu 37 1 153304141 153304141 + RNA DEL G G - rs10707075 byCluster TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000384591 +1 novel NULL 0.016 - - - - - - - - - - VANGL2 57216 genome.wustl.edu 37 1 160394931 160394931 + Silent SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_020335.1 +1 validated p.A443 0.077 161 0% 126 36.5% 3 33.3% - - - HMMPfam_Strabismus RC3H1 149041 genome.wustl.edu 37 1 173916554 173916554 + Missense_Mutation SNP T T C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_172071.2 -1 validated p.Q897R 1.000 66 0% 69 24.6% 1 0% probably_damaging(0.963) deleterious(0.01) deleterious(0.811) NULL NFASC 23114 genome.wustl.edu 37 1 204966474 204966474 + Missense_Mutation SNP G G A rs183209390 by1000genomes TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000367172 +1 known p.A1094T 0.816 17 0% 48 22.9% 0 - unknown(0) tolerated(0.52) - NULL GREB1 9687 genome.wustl.edu 37 2 11775464 11775464 + Missense_Mutation SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_014668.3 +1 reviewed p.N1760S 1.000 68 0% 43 39.5% 5 20% probably_damaging(0.998) deleterious(0) deleterious(0.919) NULL MYO1B 4430 genome.wustl.edu 37 2 192250757 192250757 + Missense_Mutation SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001130158.1 +1 validated p.N501D 1.000 407 0% 450 27.8% 8 25% benign(0.035) tolerated(0.68) neutral(0.004) HMMPfam_Myosin_head,HMMSmart_SM00242,superfamily_P-loop containing nucleoside triphosphate hydrolases GOLGA4 2803 genome.wustl.edu 37 3 37367662 37367662 + Missense_Mutation SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_002078.4 +1 reviewed p.I1429V 0.013 279 0.4% 256 31.2% 2 0% benign(0.002) tolerated(0.61) neutral(0.004) NULL DIRC2 84925 genome.wustl.edu 37 3 122591311 122591311 + Silent SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_032839.2 +1 reviewed p.S396 0.017 253 0% 165 34.5% 1 100% - - - superfamily_MFS general substrate transporter PIK3CA 5290 genome.wustl.edu 37 3 178936083 178936083 + Missense_Mutation SNP A A C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_006218.2 +1 reviewed p.E542A 1.000 120 0% 74 23% 2 50% probably_damaging(0.976) deleterious(0.03) deleterious(0.782) HMMPfam_PI3Ka,HMMSmart_PI3Ka,superfamily_ARM-type_fold DCUN1D1 54165 genome.wustl.edu 37 3 182683524 182683524 + Silent SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_020640.2 -1 validated p.S7 0.995 110 0% 108 32.4% 0 - - - - superfamily_UBA-like MUC20 200958 genome.wustl.edu 37 3 195453399 195453399 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_152673.2 +1 reviewed p.T471M 0.000 189 0% 118 23.7% 342 2.9% probably_damaging(0.999) deleterious(0.03) deleterious(0.855) NULL MUC4 4585 genome.wustl.edu 37 3 195515449 195515449 + Missense_Mutation SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_018406.5 -1 reviewed p.V1001A 0.027 13 0% 24 33.3% 4 0% benign(0.193) - - NULL TACR3 6870 genome.wustl.edu 37 4 104640323 104640323 + Silent SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001059.1 -1 reviewed p.F170 0.998 208 0% 130 30.8% 0 - - - - HMMPfam_7tm_1,superfamily_SSF81321 TNIP3 79931 genome.wustl.edu 37 4 122078351 122078351 + Missense_Mutation SNP G G T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001128843.1 -1 validated p.S87R 0.002 385 0% 230 30.9% 0 - benign(0.027) tolerated(0.07) neutral(0.321) NULL EMB 133418 genome.wustl.edu 37 5 49699177 49699177 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_198449.2 -1 reviewed p.R238C 0.927 231 0% 185 31.9% 4 0% probably_damaging(0.994) deleterious(0.02) deleterious(0.835) HMMSmart_SM00409,superfamily_Immunoglobulin ELL2 22936 genome.wustl.edu 37 5 95234255 95234255 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_012081.5 -1 validated p.R405Q 1.000 259 0% 191 34% 4 0% unknown(0) tolerated(0.41) - NULL PCDHGA11 56105 genome.wustl.edu 37 5 140802357 140802357 + Silent SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_018914.2 +1 reviewed p.F521 0.344 141 0% 117 29.9% 3 0% - - - HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like GRIA1 2890 genome.wustl.edu 37 5 153182043 153182043 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_000827.3 +1 reviewed p.R838Q 1.000 244 0% 275 29.5% 0 - probably_damaging(0.956) tolerated(0.09) deleterious(0.696) NULL OR2J1 442185 genome.wustl.edu 37 6 29069161 29069161 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000377171 +1 known p.A148T 0.001 499 0% 514 32.9% 0 - probably_damaging(0.997) tolerated(0.47) deleterious(0.477) HMMPfam_7tm_1,superfamily_SSF81321 TDRD6 221400 genome.wustl.edu 37 6 46659900 46659900 + Silent SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001010870.2 +1 validated p.P1345 0.000 322 0% 270 38.5% 0 - - - - HMMPfam_TUDOR GRM8 2918 genome.wustl.edu 37 7 126746621 126746621 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_000845.2 -1 reviewed p.S219L 1.000 113 0% 148 29.7% 0 - probably_damaging(0.988) deleterious(0) deleterious(0.882) HMMPfam_ANF_receptor,superfamily_Periplasmic binding protein-like I GLIS3 169792 genome.wustl.edu 37 9 3932433 3932433 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001042413.1 -1 reviewed p.R637H 1.000 192 0% 155 29% 1 0% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers FAM189A2 9413 genome.wustl.edu 37 9 72002911 72002912 + In_Frame_Ins INS - - GTTATA novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000377216 +1 known p.20in_frame_insYS 0.000:0.000 - - - - - - - - - NULL TRPM6 140803 genome.wustl.edu 37 9 77377340 77377340 + Missense_Mutation SNP C C A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_017662.4 -1 reviewed p.G1416V 0.000 290 0.3% 262 28.6% 0 - benign(0.039) tolerated(0.07) neutral(0.321) NULL TLE1 7088 genome.wustl.edu 37 9 84199402 84199404 + In_Frame_Del DEL GAG GAG - novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 GAG GAG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_005077.3 -1 provisional p.L722in_frame_del 1.000:1.000:1.000 - - - - - - - - - HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40 CTSL2 1515 genome.wustl.edu 37 9 99797060 99797060 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001333.2 -1 reviewed p.G285S 1.000 120 0% 97 32% 372 45.9% probably_damaging(1) deleterious(0) deleterious(0.945) PatternScan_THIOL_PROTEASE_HIS,HMMPfam_Peptidase_C1,HMMSmart_Pept_C1,superfamily_SSF54001 ZNF883 169834 genome.wustl.edu 37 9 115759419 115759419 + Missense_Mutation SNP T T C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001101338.1 -1 validated p.K374R 0.003 69 0% 75 30.7% 0 - - - - superfamily_C2H2 and C2HC zinc fingers STXBP1 6812 genome.wustl.edu 37 9 130425489 130425489 + Nonsense_Mutation SNP T T A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_003165.3 +1 reviewed p.Y145* 1.000 185 0% 168 26.2% 1 0% - - - HMMPfam_Sec1,superfamily_Sec1/munc18-like (SM) proteins ARID5B 84159 genome.wustl.edu 37 10 63850619 63850619 + Splice_Site SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_032199.2 +1 validated e10-2 1.000 227 0% 171 32.7% 1 100% - - - - NEUROG3 50674 genome.wustl.edu 37 10 71332419 71332419 + Silent SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_020999.3 -1 reviewed p.F127 0.978 37 0% 32 21.9% 0 - - - - HMMPfam_HLH,HMMSmart_HLH,superfamily_HLH_basic EIF5AL1 143244 genome.wustl.edu 37 10 81272543 81272543 + Silent SNP G G C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001099692.1 +1 validated p.S46 1.000 151 0% 120 28.3% 11 0% - - - superfamily_Transl_SH3_like PTEN 5728 genome.wustl.edu 37 10 89653857 89653857 + Frame_Shift_Del DEL A A - novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000371953 +1 known p.D52fs 1.000 - - - - - - - - - HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II NOC3L 64318 genome.wustl.edu 37 10 96101431 96101431 + Missense_Mutation SNP C C A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_022451.9 -1 provisional p.G548V 1.000 98 0% 55 34.5% 0 - probably_damaging(0.979) tolerated(0.28) neutral(0.454) NULL SH3PXD2A 9644 genome.wustl.edu 37 10 105363177 105363177 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_014631.2 -1 validated p.R572W 1.000 116 0% 75 28% 1 0% probably_damaging(0.995) deleterious(0.01) deleterious(0.863) NULL KBTBD4 55709 genome.wustl.edu 37 11 47594916 47594916 + Missense_Mutation SNP T T A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_018095.4 -1 validated p.N391Y 1.000 158 0% 78 23.1% 44 56.8% benign(0.081) deleterious(0.04) neutral(0.355) HMMPfam_Kelch_1,superfamily_Galactose oxidase central domain SPTBN2 6712 genome.wustl.edu 37 11 66460504 66460504 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_006946.2 -1 reviewed p.A1641V 1.000 134 0% 171 26.3% 21 28.5% probably_damaging(0.999) deleterious(0.01) deleterious(0.896) HMMPfam_Spectrin,HMMSmart_SM00150,superfamily_Spectrin repeat KRAS 3845 genome.wustl.edu 37 12 25398281 25398281 + Missense_Mutation SNP C C T rs112445441 byCluster TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_033360.2 -1 reviewed p.G13D 1.000 85 0% 24 20.8% 3 0% benign(0.184) deleterious(0) neutral(0.462) HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases LIMA1 51474 genome.wustl.edu 37 12 50594602 50594602 + Silent SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001113546.1 -1 validated p.P310 1.000 370 0% 326 27.6% 4 50% - - - NULL NR2C1 7181 genome.wustl.edu 37 12 95425249 95425249 + Missense_Mutation SNP T T C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_003297.2 -1 reviewed p.I423M 1.000 108 0% 119 26.1% 4 25% probably_damaging(0.961) tolerated(0.06) deleterious(0.727) HMMPfam_Hormone_recep,HMMSmart_SM00430,superfamily_Nuclear receptor ligand-binding domain BRAP 8315 genome.wustl.edu 37 12 112110570 112110570 + Silent SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_006768.3 -1 reviewed p.A214 0.562 67 0% 58 31% 4 50% - - - HMMPfam_BRAP2 XPO4 64328 genome.wustl.edu 37 13 21417926 21417926 + Missense_Mutation SNP A A G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_022459.4 -1 validated p.C186R 1.000 147 0% 101 32.7% 0 - benign(0.361) tolerated(0.06) neutral(0.437) superfamily_ARM-type_fold LOC643677 643677 genome.wustl.edu 37 13 103390701 103390701 + Missense_Mutation SNP A A T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba XM_002344085.1 -1 model p.Y4045N 0.000 6 0.000 14 0.286 0 - - - - NULL OR10G3 26533 genome.wustl.edu 37 14 22038134 22038134 + Missense_Mutation SNP C C A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001005465.1 -1 validated p.V248L 0.773 109 0% 85 30.6% 0 - benign(0.175) deleterious(0.01) neutral(0.422) HMMPfam_7tm_1,superfamily_SSF81321 MAGEL2 54551 genome.wustl.edu 37 15 23889144 23889144 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_019066.4 -1 reviewed p.R646H 0.037 25 0% 14 28.6% 2 0% benign(0.001) deleterious(0) neutral(0.445) NULL USP50 373509 genome.wustl.edu 37 15 50835873 50835873 + Silent SNP T T G rs60073047 byCluster;byFrequency;by1000genomes TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_203494.4 -1 validated p.A127 0.000 69 0% 46 32.6% 0 - - - - HMMPfam_UCH,superfamily_SSF54001 ZNF592 9640 genome.wustl.edu 37 15 85341940 85341940 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_014630.2 +1 validated p.A953V 0.004 37 0% 18 27.8% 9 55.5% benign(0.011) tolerated(0.27) neutral(0.034) NULL CTCF 10664 genome.wustl.edu 37 16 67654646 67654646 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_006565.2 +1 reviewed p.P378L 1.000 231 0% 254 28.7% 11 36.3% probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_C2H2 and C2HC zinc fingers RFWD3 55159 genome.wustl.edu 37 16 74694858 74694858 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_018124.3 -1 validated p.G164R 0.457 97 0% 142 27.5% 1 0% benign(0.041) tolerated(0.22) neutral(0.045) NULL SLC25A39 51629 genome.wustl.edu 37 17 42398525 42398525 + Frame_Shift_Del DEL C C - novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001143780.1 -1 validated p.E198fs 1.000 - - - - - - - - - superfamily_Mitoch_carrier,HMMPfam_Mito_carr MAP3K14 9020 genome.wustl.edu 37 17 43344806 43344806 + Missense_Mutation SNP C C G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000344686 -1 known p.V764L 0.431 12 0% 10 40% 3 33.3% benign(0) tolerated(1) - NULL ENSG00000188755 0 genome.wustl.edu 37 17 60351235 60351235 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba ENST00000339120 -1 known p.R27Q 0.180 165 0% 71 32.4% 0 - benign(0.09) tolerated(0.25) neutral(0.043) NULL ABCA10 10349 genome.wustl.edu 37 17 67215691 67215691 + Silent SNP T T C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_080282.3 -1 reviewed p.A175 0.998 173 0% 158 27.2% 0 - - - - NULL TUBB4A 10382 genome.wustl.edu 37 19 6495585 6495585 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_006087.2 -1 provisional p.R309C 1.000 145 0% 148 29.1% 0 - probably_damaging(1) - - superfamily_Tubulin C-terminal domain-like,HMMPfam_Tubulin_C CACNA1A 773 genome.wustl.edu 37 19 13428040 13428040 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_001127222.1 -1 reviewed p.R481C 1.000 92 0% 82 32.9% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_Voltage-gated potassium channels WIZ 58525 genome.wustl.edu 37 19 15537900 15537900 + Missense_Mutation SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_021241.2 -1 validated p.R325Q 1.000 50 0% 17 29.4% 4 25% unknown(0) tolerated(0.16) - NULL LOC388514 388514 genome.wustl.edu 37 19 15871673 15871673 + RNA SNP C C T novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba XR_017598.3 -1 model NULL 0.000 236 0% 176 30.7% 0 - - - - - ZNF229 7772 genome.wustl.edu 37 19 44933253 44933253 + Missense_Mutation SNP C C A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_014518.2 -1 validated p.G568V 0.816 200 0% 200 31% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_C2H2 and C2HC zinc fingers PLEKHA4 57664 genome.wustl.edu 37 19 49370850 49370850 + Missense_Mutation SNP G G C novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_020904.2 -1 validated p.L10V 1.000 13 0% 14 50% 19 26.3% possibly_damaging(0.938) tolerated(0.68) neutral(0.386) NULL ZNF337 26152 genome.wustl.edu 37 20 25657467 25657467 + Missense_Mutation SNP C C G novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_015655.2 -1 validated p.E153Q 0.000 487 0% 323 26.9% 3 33.3% possibly_damaging(0.497) tolerated(0.43) neutral(0.180) NULL PCK1 5105 genome.wustl.edu 37 20 56139404 56139404 + Missense_Mutation SNP G G A novel TCGA-BG-A0MC-01A-21W-A062-09 TCGA-BG-A0MC-10A-01W-A062-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 084092b4-2434-4735-b4bc-a99e8e82768e 602111a2-06a1-4674-9a16-436f572d86ba NM_002591.3 +1 reviewed p.V381I 0.720 79 0% 78 33.3% 5 60% benign(0.001) tolerated(0.23) neutral(0.042) HMMPfam_PEPCK,superfamily_SSF53795