Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain ENSG00000245549 0 genome.wustl.edu 37 1 16950252 16950252 + RNA DEL G G - rs140356375 byCluster;by1000genomes TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 ENST00000501442 +1 novel NULL 0.356 - - - - - - - - - - TMCO4 255104 genome.wustl.edu 37 1 20107210 20107210 + Silent SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_181719.4 -1 validated p.Q14 0.035 19 0% 18 55.6% 9 44.4% - - - NULL LCE2C 353140 genome.wustl.edu 37 1 152648586 152648586 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_178429.2 +1 validated p.C32F 0.001 549 0.2% 965 22.4% 0 - unknown(0) - - NULL KPRP 448834 genome.wustl.edu 37 1 152732998 152732998 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001025231.1 +1 provisional p.R312C 0.000 39 0% 61 23% 0 - possibly_damaging(0.703) tolerated(0.09) deleterious(0.549) NULL CD1C 911 genome.wustl.edu 37 1 158261109 158261109 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001765.2 +1 reviewed p.D83Y 0.000 237 0% 401 72.6% 0 - benign(0.003) deleterious(0.04) neutral(0.349) HMMPfam_MHC_I,superfamily_MHC_I/II-like_Ag-recog ADCY3 109 genome.wustl.edu 37 2 25042928 25042928 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_004036.3 -1 reviewed p.R1103Q 1.000 58 0% 73 46.6% 20 35% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Guanylate_cyc,superfamily_A/G_cyclase SERTAD2 9792 genome.wustl.edu 37 2 64863705 64863705 + Nonsense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_014755.2 -1 validated p.R101* 1.000 90 0% 102 50% 4 50% - - - NULL GPR39 2863 genome.wustl.edu 37 2 133402828 133402828 + Silent SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001508.2 +1 validated p.S337 0.135 114 0.9% 115 50.4% 43 44.1% - - - HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like FAP 2191 genome.wustl.edu 37 2 163070551 163070551 + Missense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_004460.2 -1 reviewed p.T300I 0.967 150 0% 167 50.3% 0 - possibly_damaging(0.772) deleterious(0) deleterious(0.732) HMMPfam_DPPIV_N,superfamily_SSF82171 ATG9A 79065 genome.wustl.edu 37 2 220088389 220088389 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001077198.1 -1 validated p.R506Q 1.000 114 0% 87 43.7% 21 38% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_APG9 HTR3C 170572 genome.wustl.edu 37 3 183772635 183772635 + Missense_Mutation SNP G G A rs183919204 by1000genomes TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_130770.2 +1 reviewed p.R65H 0.000 140 0.7% 133 49.6% 0 - benign(0.001) tolerated(0.57) neutral(0.006) HMMPfam_Neur_chan_LBD,superfamily_Neur_chan_LBD FBXW7 55294 genome.wustl.edu 37 4 153244092 153244092 + Missense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_033632.2 -1 reviewed p.R689W 1.000 490 0% 409 44% 8 12.5% probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00320 PCDHGB3 56102 genome.wustl.edu 37 5 140751467 140751467 + Silent SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_018924.2 +1 reviewed p.S502 0.002 18 0% 22 50% 0 - - - - HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like ENSG00000229119 0 genome.wustl.edu 37 5 165809567 165809567 + Silent SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 ENST00000449646 +1 known p.S86 1.000 134 0% 143 31.5% 1912 0% - - - HMMPfam_Ribosomal_60s ODZ2 57451 genome.wustl.edu 37 5 166802271 166802271 + Missense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001122679.1 +1 inferred p.D99N 1.000 61 0% 63 39.7% 0 - possibly_damaging(0.943) deleterious(0.01) deleterious(0.793) HMMPfam_Ten_N RIPK1 8737 genome.wustl.edu 37 6 3085631 3085631 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_003804.3 +1 validated p.P276L 0.998 125 0% 135 40.7% 6 66.6% probably_damaging(0.962) deleterious(0) deleterious(0.850) HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase PGBD1 84547 genome.wustl.edu 37 6 28269865 28269865 + Missense_Mutation SNP T T C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_032507.3 +1 reviewed p.I745T 0.904 280 0% 263 49.4% 0 - possibly_damaging(0.722) tolerated(0.07) deleterious(0.581) NULL COL12A1 1303 genome.wustl.edu 37 6 75814951 75814951 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_004370.5 -1 reviewed p.V2746I 0.945 158 0% 182 48.9% 11 18.1% unknown(0) - - NULL ENPP1 5167 genome.wustl.edu 37 6 132195422 132195422 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_006208.2 +1 reviewed p.R527M 0.004 344 0% 355 36.9% 1 100% benign(0.186) tolerated(0.14) neutral(0.267) HMMPfam_Phosphodiest,superfamily_Alkaline_phosphatase_core PPP1R3A 5506 genome.wustl.edu 37 7 113518304 113518304 + Missense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_002711.3 -1 reviewed p.T948M 0.004 177 0.6% 154 56.5% 0 - possibly_damaging(0.859) deleterious(0) deleterious(0.776) NULL AGPAT5 55326 genome.wustl.edu 37 8 6614840 6614840 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_018361.3 +1 reviewed p.R342S 1.000 316 0% 337 46.6% 17 64.7% probably_damaging(1) deleterious(0) deleterious(0.945) NULL SOX17 64321 genome.wustl.edu 37 8 55372518 55372518 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_022454.3 +1 reviewed p.S403I 1.000 32 0% 36 58.3% 532 46.2% probably_damaging(0.998) deleterious(0) deleterious(0.919) NULL FAM83H 286077 genome.wustl.edu 37 8 144808129 144808129 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_198488.3 -1 reviewed p.V1168M 1.000 18 0% 22 45.5% 25 36% benign(0) tolerated(0.48) neutral(0.011) NULL C9orf152 401546 genome.wustl.edu 37 9 112969712 112969712 + Missense_Mutation SNP T T C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001012993.2 -1 validated p.K50E 0.980 113 0.9% 112 35.7% 4 50% benign(0.401) deleterious(0.05) deleterious(0.474) NULL PTEN 5728 genome.wustl.edu 37 10 89720650 89720650 + Splice_Site SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 ENST00000371953 +1 known e8-1 1.000 141 0% 104 94.2% 0 - - - - - JAKMIP3 282973 genome.wustl.edu 37 10 133954024 133954024 + Missense_Mutation SNP T T A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001105521.2 +1 provisional p.S472T 1.000 96 0% 80 45% 0 - possibly_damaging(0.444) deleterious(0.01) deleterious(0.550) NULL MYBPC3 4607 genome.wustl.edu 37 11 47365114 47365114 + Silent SNP G G C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_000256.3 -1 reviewed p.T384 0.138 121 0% 121 47.1% 0 - - - - HMMSmart_IG,HMMPfam_I-set,superfamily_SSF48726 MS4A1 931 genome.wustl.edu 37 11 60233393 60233393 + Splice_Site SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_021950.3 +1 reviewed e4-1 1.000 195 0% 171 53.2% 0 - - - - - OTUB1 55611 genome.wustl.edu 37 11 63765247 63765247 + RNA SNP C C T rs55951521 byCluster;byFrequency;by1000genomes TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NR_003089.1 +1 reviewed NULL 0.000 1 0.000 4 1.000 69 63.7% - - - - CHD4 1108 genome.wustl.edu 37 12 6697106 6697106 + Missense_Mutation SNP T T C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001273.2 -1 reviewed p.R1159G 1.000 124 0% 134 44.8% 66 48.4% probably_damaging(0.998) deleterious(0) deleterious(0.919) HMMPfam_Helicase_C,HMMSmart_SM00490,superfamily_P-loop containing nucleoside triphosphate hydrolases ABCC9 10060 genome.wustl.edu 37 12 22015985 22015985 + Silent SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_005691.2 -1 reviewed p.R747 1.000 140 0% 158 41.8% 0 - - - - HMMPfam_ABC_tran,HMMSmart_SM00382,superfamily_P-loop containing nucleoside triphosphate hydrolases OTOGL 283310 genome.wustl.edu 37 12 80771812 80771812 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 XM_002343203.1 +1 model p.T2246M 0.999 192 0% 178 46.6% 0 - probably_damaging(0.999) tolerated(0.08) deleterious(0.790) HMMSmart_SM00041 SPTB 6710 genome.wustl.edu 37 14 65219006 65219007 + Frame_Shift_Ins INS - - CTCCT novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 ENST00000335612 -1 known p.E995fs 0.000:0.000 - - - - - - - - - HMMPfam_PH,HMMSmart_SM00233,HMMSmart_SM00150,superfamily_PH domain-like FAM98B 283742 genome.wustl.edu 37 15 38776549 38776549 + Missense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_173611.2 +1 validated p.G331S 0.997 53 0% 63 30.2% 18 55.5% unknown(0) tolerated(0.12) - HMMPfam_DUF2465 THBS1 7057 genome.wustl.edu 37 15 39881531 39881531 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 ENST00000397593 +1 known p.S68L 0.009 71 0% 91 16.5% 173 21.9% unknown(0) - - NULL USP8 9101 genome.wustl.edu 37 15 50769543 50769543 + Silent SNP T T C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001128610.1 +1 validated p.S355 0.464 151 0% 149 47% 8 25% - - - NULL MYH11 4629 genome.wustl.edu 37 16 15844130 15844130 + Silent SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001040114.1 -1 reviewed p.S648 0.670 123 0% 107 48.6% 6 0% - - - HMMPfam_Myosin_head,HMMSmart_MYSc,superfamily_SSF52540 CNOT1 23019 genome.wustl.edu 37 16 58610458 58610458 + Missense_Mutation SNP A A G novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_016284.3 -1 validated p.I538T 1.000 401 0% 362 46.1% 51 49% benign(0.025) tolerated(0.06) neutral(0.324) NULL FAM101B 359845 genome.wustl.edu 37 17 295704 295704 + Silent SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_182705.2 -1 validated p.P10L 0.000 61 0% 64 42.2% 4 50% - - - NULL MYH4 4622 genome.wustl.edu 37 17 10348573 10348573 + Missense_Mutation SNP G G C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_017533.2 -1 validated p.A1759G 1.000 614 0% 605 19% 0 - probably_damaging(1) tolerated(0.12) deleterious(0.760) HMMPfam_Myosin_tail_1 MYH4 4622 genome.wustl.edu 37 17 10363578 10363578 + Missense_Mutation SNP C C A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_017533.2 -1 validated p.C403F 1.000 248 0% 256 46.9% 0 - probably_damaging(0.998) deleterious(0.01) deleterious(0.880) HMMPfam_Myosin_head,HMMSmart_MYSc,superfamily_SSF52540 TMEM11 8834 genome.wustl.edu 37 17 21101964 21101964 + Silent SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_003876.2 -1 validated p.T84 1.000 37 0% 41 17.1% 40 35% - - - NULL FCGBP 8857 genome.wustl.edu 37 19 40395971 40395971 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_003890.2 -1 validated p.V2476M 0.378 172 0% 121 17.4% 6 0% unknown(0) tolerated(0.06) - HMMPfam_VWD,HMMSmart_VWD AXL 558 genome.wustl.edu 37 19 41745068 41745068 + Splice_Site SNP G G C novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_021913.3 +1 reviewed e9-1 1.000 147 0% 137 18.2% 0 - - - - - GPR4 2828 genome.wustl.edu 37 19 46094994 46094994 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_005282.2 -1 validated p.R44H 0.999 44 0% 42 38.1% 5 0% possibly_damaging(0.907) tolerated(0.12) deleterious(0.621) HMMPfam_7tm_1,superfamily_SSF81321 KLK6 5653 genome.wustl.edu 37 19 51466671 51466671 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001012964.1 -1 reviewed p.R111H 0.002 154 0% 145 48.3% 0 - benign(0.133) tolerated(0.18) neutral(0.067) HMMPfam_Trypsin,HMMSmart_SM00020,superfamily_Trypsin-like serine proteases ARVCF 421 genome.wustl.edu 37 22 19961187 19961187 + Missense_Mutation SNP G G A novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001670.1 -1 reviewed p.R740W 1.000 22 0% 27 25.9% 23 26% probably_damaging(0.982) deleterious(0.02) deleterious(0.809) superfamily_ARM repeat WWC3 55841 genome.wustl.edu 37 X 10093129 10093129 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_015691.3 +1 validated p.A631V 0.000 43 0% 49 46.9% 1 0% benign(0) tolerated(1) - superfamily_C2 domain (Calcium/lipid-binding domain CaLB) MAP7D2 256714 genome.wustl.edu 37 X 20071071 20071071 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_152780.3 -1 validated p.P174T 1.000 401 0% 436 41.7% 3 0% possibly_damaging(0.916) tolerated(0.6) neutral(0.371) NULL HNRNPH2 3188 genome.wustl.edu 37 X 100668007 100668007 + Frame_Shift_Del DEL C C - novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001032393.1 +1 reviewed p.A344fs 1.000 - - - - - - - - - HMMPfam_RRM_1,HMMSmart_SM00360,superfamily_RNA-binding domain RBD RHOXF1 158800 genome.wustl.edu 37 X 119249509 119249509 + Silent SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_139282.1 -1 provisional p.P88 0.000 39 0% 40 37.5% 0 - - - - superfamily_Homeodomain_like IGSF1 3547 genome.wustl.edu 37 X 130411977 130411977 + Missense_Mutation SNP G G T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_001555.4 -1 reviewed p.Q725K 1.000 375 0% 369 45.8% 0 - possibly_damaging(0.916) tolerated(0.35) neutral(0.388) HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_ig,superfamily_Immunoglobulin RAP2C 57826 genome.wustl.edu 37 X 131348375 131348375 + Missense_Mutation SNP C C T novel TCGA-BK-A13C-01A-11D-A122-09 TCGA-BK-A13C-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 22a09a9f-c249-4623-ab1b-e4b059d1dfec d8c5fada-ec4c-4add-ae51-99ccfbcadd61 NM_021183.3 -1 provisional p.E125K 1.000 302 0.7% 262 44.3% 7 85.7% possibly_damaging(0.92) tolerated(0.58) neutral(0.376) HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases