Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain MYOM3 127294 genome.wustl.edu 37 1 24432425 24432425 + Missense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_152372.3 -1 validated p.P182Q 0.878 28 0% 20 20% 0 - possibly_damaging(0.446) tolerated(0.57) neutral(0.152) HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin SZT2 23334 genome.wustl.edu 37 1 43868851 43868851 + Nonsense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001012961.1 +1 validated p.E11* 1.000 391 0% 588 15.5% 1 0% - - - NULL GLMN 11146 genome.wustl.edu 37 1 92712183 92712183 + Missense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_053274.2 -1 reviewed p.F563L 1.000 439 0% 631 40.7% 26 57.6% possibly_damaging(0.793) tolerated(0.66) neutral(0.300) HMMPfam_FKBP12 GLMN 11146 genome.wustl.edu 37 1 92712184 92712184 + Missense_Mutation SNP A A T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_053274.2 -1 reviewed p.F563Y 1.000 436 0% 618 39.8% 24 58.3% possibly_damaging(0.916) tolerated(1) neutral(0.367) HMMPfam_FKBP12 F5 2153 genome.wustl.edu 37 1 169524517 169524517 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_000130.4 -1 reviewed p.R341C 0.000 365 0% 508 41.9% 0 - probably_damaging(1) deleterious(0.01) deleterious(0.905) NULL QPCT 25797 genome.wustl.edu 37 2 37580047 37580047 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_012413.3 +1 reviewed p.P79L 1.000 209 0% 340 52.4% 7 14.2% probably_damaging(1) tolerated(0.22) deleterious(0.542) superfamily_Zn-dependent exopeptidases ERMN 57471 genome.wustl.edu 37 2 158178248 158178248 + Missense_Mutation SNP C C G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001009959.1 -1 validated p.Q143H 0.000 263 0% 326 39.9% 0 - possibly_damaging(0.76) deleterious(0) deleterious(0.726) NULL AGAP1 116987 genome.wustl.edu 37 2 237028848 237028848 + Silent SNP A A G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e ENST00000418654 +1 known p.T262A 0.965 38 0% 37 43.2% 5 60% - - - HMMPfam_ArfGap,HMMSmart_SM00105,superfamily_Pyk2-associated protein beta ARF-GAP domain LRRFIP1 9208 genome.wustl.edu 37 2 238626419 238626419 + Silent SNP G G C novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001137550.1 +1 validated p.L72 1.000 602 0% 712 36.1% 0 - - - - HMMPfam_DUF2051 ZNF717 100131827 genome.wustl.edu 37 3 75786971 75786971 + Silent SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001128223.1 -1 validated p.I601 0.000 401 0% 236 24.6% 0 - - - - HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers ILDR1 286676 genome.wustl.edu 37 3 121720691 121720691 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_175924.2 -1 provisional p.E134K 1.000 215 0% 220 61.4% 0 - probably_damaging(0.971) tolerated(0.12) deleterious(0.673) HMMSmart_IG,superfamily_SSF48726 GPR171 29909 genome.wustl.edu 37 3 150917053 150917053 + Missense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_013308.3 -1 validated p.Q41K 0.864 120 0% 192 41.1% 0 - benign(0.138) tolerated(0.19) neutral(0.061) HMMPfam_7tm_1,superfamily_SSF81321 PIK3CA 5290 genome.wustl.edu 37 3 178936083 178936083 + Missense_Mutation SNP A A C novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_006218.2 +1 reviewed p.E542A 1.000 368 0% 529 77.3% 3 100% probably_damaging(0.976) deleterious(0.03) deleterious(0.782) HMMPfam_PI3Ka,HMMSmart_PI3Ka,superfamily_ARM-type_fold C4orf27 54969 genome.wustl.edu 37 4 170669973 170669973 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_017867.2 -1 validated p.P140L 1.000 245 0% 179 47.5% 1 100% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_DUF2228 ODZ3 55714 genome.wustl.edu 37 4 183714097 183714097 + Frame_Shift_Del DEL A A - novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001080477.1 +1 provisional p.Q2091fs 1.000 - - - - - - - - - NULL PLEKHG4B 153478 genome.wustl.edu 37 5 174102 174102 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_052909.3 +1 validated p.R1075W 1.000 110 0% 136 35.3% 3 33.3% probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00233,superfamily_PH domain-like RIOK2 55781 genome.wustl.edu 37 5 96500768 96500768 + Nonsense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_018343.2 -1 validated p.S494* 1.000 353 0% 387 26.4% 15 26.6% - - - NULL PCDHB3 56132 genome.wustl.edu 37 5 140482454 140482454 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_018937.2 +1 reviewed p.G741S 0.000 185 0% 226 32.7% 7 0% benign(0.085) deleterious(0.03) neutral(0.370) NULL BTNL3 10917 genome.wustl.edu 37 5 180432415 180432415 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_197975.1 +1 validated p.P315L 0.000 311 0% 541 35.3% 0 - benign(0.403) tolerated(0.08) neutral(0.429) HMMSmart_PRY RANBP9 10048 genome.wustl.edu 37 6 13622615 13622615 + Silent SNP T T C novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_005493.2 -1 reviewed p.T723 0.998 128 0% 157 38.2% 25 60% - - - HMMPfam_RanBPM_CRA CYP21A2 1589 genome.wustl.edu 37 6 32006215 32006217 + In_Frame_Del DEL CTG CTG - rs138498156 by1000genomes TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 CTG CTG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_000500.5 +1 reviewed p.L9in_frame_del 0.286:0.956:0.978 - - - - - - - - - NULL VNN1 8876 genome.wustl.edu 37 6 133013590 133013590 + Silent SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_004666.2 -1 reviewed p.A320 0.031 258 0% 305 18.4% 0 - - - - NULL COX19 90639 genome.wustl.edu 37 7 975071 975071 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e ENST00000457254 -1 known p.P89S 1.000 46 0% 62 43.5% 12 25% benign(0.007) deleterious(0.03) neutral(0.364) NULL VWDE 221806 genome.wustl.edu 37 7 12412797 12412797 + Nonsense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001135924.1 -1 provisional p.Q465* 1.000 185 0% 324 17.9% 0 - - - - HMMSmart_SM00216 SEMA3C 10512 genome.wustl.edu 37 7 80374328 80374328 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_006379.2 -1 validated p.R713Q 0.998 323 0% 307 13% 1 100% benign(0.301) tolerated(0.33) neutral(0.117) NULL TMEM66 51669 genome.wustl.edu 37 8 29931531 29931531 + Silent SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_016127.4 -1 provisional p.H48 0.836 265 0% 220 68.6% 8 62.5% - - - HMMPfam_DUF1183 NOV 4856 genome.wustl.edu 37 8 120435253 120435253 + Nonsense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_002514.3 +1 reviewed p.Q319* 0.006 36 0% 59 37.3% 2 0% - - - HMMSmart_CT,PatternScan_CTCK_1,HMMPfam_Cys_knot SLC24A2 25769 genome.wustl.edu 37 9 19521031 19521031 + Missense_Mutation SNP C C G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_020344.1 -1 provisional p.E533Q 1.000 172 0% 135 69.6% 0 - probably_damaging(0.995) tolerated(0.14) deleterious(0.707) HMMPfam_Na_Ca_ex UCN3 114131 genome.wustl.edu 37 10 5415797 5415797 + Silent SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_053049.2 +1 reviewed p.T38 0.995 42 0% 56 39.3% 0 - - - - NULL CCAR1 55749 genome.wustl.edu 37 10 70507314 70507314 + Nonsense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_018237.2 +1 validated p.Q273* 1.000 239 0% 400 38.3% 1 0% - - - NULL ZRANB1 54764 genome.wustl.edu 37 10 126672204 126672204 + Missense_Mutation SNP C C G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_017580.2 +1 validated p.L619V 1.000 237 0% 307 38.1% 22 13.6% probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL GPR123 84435 genome.wustl.edu 37 10 134912161 134912161 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001083909.1 +1 validated p.R50H 0.867 23 0% 32 25% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_7tm_2 NAV2 89797 genome.wustl.edu 37 11 20072852 20072852 + Frame_Shift_Del DEL G G - novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_182964.5 +1 validated p.N1486fs 1.000 - - - - - - - - - NULL C1QTNF5 114902 genome.wustl.edu 37 11 119210202 119210202 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_015645.3 -1 reviewed p.L191F 0.998 79 0% 61 42.6% 14 14.2% probably_damaging(0.991) tolerated(0.16) deleterious(0.504) HMMPfam_C1q,HMMSmart_C1Q,superfamily_TNF_like RBP5 83758 genome.wustl.edu 37 12 7281367 7281367 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_031491.2 -1 provisional p.P2L 1.000 357 0% 303 11.9% 10 0% unknown(0) deleterious(0) - superfamily_Calycin FAM90A1 55138 genome.wustl.edu 37 12 8374781 8374782 + In_Frame_Ins INS - - ACG rs71265055 byCluster;by1000genomes TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_018088.3 -1 validated p.345in_frame_insV 0.003:0.001 - - - - - - - - - NULL SCN8A 6334 genome.wustl.edu 37 12 52200920 52200920 + Missense_Mutation SNP G G A rs147578087 by1000genomes TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_014191.2 +1 reviewed p.E1884K 1.000 47 0% 51 25.5% 4 50% probably_damaging(0.999) deleterious(0.03) deleterious(0.855) NULL COQ10A 93058 genome.wustl.edu 37 12 56662856 56662856 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_144576.3 +1 validated p.E99K 1.000 277 0% 307 47.6% 6 50% benign(0.108) tolerated(0.1) neutral(0.295) HMMPfam_Polyketide_cyc ZFC3H1 196441 genome.wustl.edu 37 12 72009091 72009091 + Missense_Mutation SNP A A G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_144982.4 -1 validated p.L1717P 1.000 243 0% 270 27.8% 1 0% probably_damaging(0.996) deleterious(0) deleterious(0.906) NULL LRFN5 145581 genome.wustl.edu 37 14 42357117 42357117 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_152447.3 +1 validated p.T430M 0.996 149 0% 158 11.4% 2 0% probably_damaging(0.987) deleterious(0) deleterious(0.881) HMMPfam_fn3,superfamily_FN_III-like BRD7 29117 genome.wustl.edu 37 16 50383999 50383999 + Missense_Mutation SNP T T C novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_013263.3 -1 validated p.M176V 1.000 777 0% 955 44.8% 5 60% probably_damaging(0.984) deleterious(0) deleterious(0.875) HMMPfam_Bromodomain,HMMSmart_SM00297,superfamily_Bromodomain TP53 7157 genome.wustl.edu 37 17 7577551 7577551 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_000546.4 -1 reviewed p.G244S 1.000 85 0% 73 68.5% 15 80% possibly_damaging(0.721) deleterious(0) deleterious(0.706) PatternScan_P53,superfamily_p53-like transcription factors,HMMPfam_P53 SLC47A1 55244 genome.wustl.edu 37 17 19445707 19445707 + Missense_Mutation SNP T T G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_018242.2 +1 validated p.F46C 0.998 227 0% 237 26.2% 0 - probably_damaging(0.998) deleterious(0.02) deleterious(0.857) HMMPfam_MatE MRI1 84245 genome.wustl.edu 37 19 13879242 13879242 + Silent SNP C C G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_032285.2 +1 validated p.P147 0.000 47 0% 123 78% 14 78.5% - - - superfamily_SSF100950 SIGLEC6 946 genome.wustl.edu 37 19 52033179 52033179 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001245.5 -1 validated p.R271W 0.001 383 0% 570 43.5% 0 - probably_damaging(0.999) deleterious(0.02) deleterious(0.873) HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin PPP2R1A 5518 genome.wustl.edu 37 19 52716323 52716323 + Missense_Mutation SNP C C A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_014225.5 +1 reviewed p.S256Y 1.000 33 0% 39 33.3% 108 41.6% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_HEAT,superfamily_ARM repeat CSNK2A1 1457 genome.wustl.edu 37 20 480518 480518 + Missense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001895.3 -1 reviewed p.P92T 1.000 382 0% 539 46.6% 2 50% benign(0.003) tolerated(0.17) neutral(0.059) HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase IFT52 51098 genome.wustl.edu 37 20 42232867 42232867 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_016004.2 +1 validated p.E128K 1.000 423 0.2% 657 49.3% 5 80% probably_damaging(0.998) deleterious(0.01) deleterious(0.880) NULL MMP11 4320 genome.wustl.edu 37 22 24121497 24121497 + Missense_Mutation SNP C C T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_005940.3 +1 reviewed p.P78S 0.985 4 0.000 9 0.667 52 46.1% unknown(0) tolerated(0.27) - PatternScan_CYSTEINE_SWITCH LIMK2 3985 genome.wustl.edu 37 22 31662113 31662113 + Missense_Mutation SNP A A G novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_001031801.1 +1 reviewed p.I325V 1.000 181 0% 252 66.3% 15 100% probably_damaging(0.987) tolerated(0.29) neutral(0.466) superfamily_Kinase_like,PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase CCNB3 85417 genome.wustl.edu 37 X 50053708 50053708 + Missense_Mutation SNP G G A novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_033031.2 +1 reviewed p.E847K 0.000 111 0% 104 26.9% 0 - possibly_damaging(0.875) deleterious(0) deleterious(0.784) NULL HAUS7 55559 genome.wustl.edu 37 X 152722109 152722109 + Missense_Mutation SNP G G T novel TCGA-D1-A16S-01A-11D-A12J-09 TCGA-D1-A16S-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5fd61ddd-c5fb-4627-8143-a2478fa5085c b57c8a4b-6c1b-45c8-9cdb-9e4513863d8e NM_017518.6 -1 reviewed p.S159R 0.083 39 0% 42 19% 61 19.6% probably_damaging(0.999) tolerated(0.25) deleterious(0.527) NULL